http://togogenome.org/gene/400065:CKV83_RS07080 ^@ http://purl.uniprot.org/uniprot/A0A239SWM9 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/400065:CKV83_RS08765 ^@ http://purl.uniprot.org/uniprot/A0A239SX72 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/400065:CKV83_RS07180 ^@ http://purl.uniprot.org/uniprot/A0A239SUX4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS00475 ^@ http://purl.uniprot.org/uniprot/A0A239SMP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS01005 ^@ http://purl.uniprot.org/uniprot/A0A239SNB5 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/400065:CKV83_RS05005 ^@ http://purl.uniprot.org/uniprot/A0A239SST2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/400065:CKV83_RS02655 ^@ http://purl.uniprot.org/uniprot/A0A239SNX7 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/400065:CKV83_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A239SVJ9 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/400065:CKV83_RS01330 ^@ http://purl.uniprot.org/uniprot/A0A239SMB9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the KduI family.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. http://togogenome.org/gene/400065:CKV83_RS11095 ^@ http://purl.uniprot.org/uniprot/A0A239T2P7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/400065:CKV83_RS00345 ^@ http://purl.uniprot.org/uniprot/A0A239SLD5 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/400065:CKV83_RS01190 ^@ http://purl.uniprot.org/uniprot/A0A239SMK3 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/400065:CKV83_RS00055 ^@ http://purl.uniprot.org/uniprot/A0A239SKL9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS01505 ^@ http://purl.uniprot.org/uniprot/A0A239SMF3 ^@ Similarity ^@ Belongs to the UPF0346 family. http://togogenome.org/gene/400065:CKV83_RS09570 ^@ http://purl.uniprot.org/uniprot/A0A239SYG3 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/400065:CKV83_RS08405 ^@ http://purl.uniprot.org/uniprot/A0A239SXH8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS04500 ^@ http://purl.uniprot.org/uniprot/A0A239SS87 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS01570 ^@ http://purl.uniprot.org/uniprot/A0A239SMY0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS07625 ^@ http://purl.uniprot.org/uniprot/A0A239SY43 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS10740 ^@ http://purl.uniprot.org/uniprot/A0A239T073 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/400065:CKV83_RS04525 ^@ http://purl.uniprot.org/uniprot/A0A239SSA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A239ST77 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS00340 ^@ http://purl.uniprot.org/uniprot/A0A239SKZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/400065:CKV83_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A239SV24 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS08795 ^@ http://purl.uniprot.org/uniprot/A0A239SZZ7 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/400065:CKV83_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A239SXN2 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/400065:CKV83_RS08385 ^@ http://purl.uniprot.org/uniprot/A0A239SYI4 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/400065:CKV83_RS04965 ^@ http://purl.uniprot.org/uniprot/A0A239SST6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS03330 ^@ http://purl.uniprot.org/uniprot/A0A239SQE0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 'phage' integrase family. XerS subfamily.|||Cytoplasm|||FtsK is required for recombination.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. http://togogenome.org/gene/400065:CKV83_RS08665 ^@ http://purl.uniprot.org/uniprot/A0A239SX69 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/400065:CKV83_RS03345 ^@ http://purl.uniprot.org/uniprot/A0A239SQF6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/400065:CKV83_RS03885 ^@ http://purl.uniprot.org/uniprot/A0A239SRB9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/400065:CKV83_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A239SMT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS06550 ^@ http://purl.uniprot.org/uniprot/A0A239SUA1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SprT family.|||Binds 1 zinc ion.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS10680 ^@ http://purl.uniprot.org/uniprot/A0A239T0Q6 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS04855 ^@ http://purl.uniprot.org/uniprot/A0A239SSP4 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/400065:CKV83_RS08225 ^@ http://purl.uniprot.org/uniprot/A0A239SX88 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/400065:CKV83_RS07395 ^@ http://purl.uniprot.org/uniprot/A0A239SV99 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS01245 ^@ http://purl.uniprot.org/uniprot/A0A239SM32 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/400065:CKV83_RS07865 ^@ http://purl.uniprot.org/uniprot/A0A239SW21 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/400065:CKV83_RS02160 ^@ http://purl.uniprot.org/uniprot/A0A239SPY1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/400065:CKV83_RS11010 ^@ http://purl.uniprot.org/uniprot/A0A239T130 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/400065:CKV83_RS04260 ^@ http://purl.uniprot.org/uniprot/A0A239SRX1 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family. LacC subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/400065:CKV83_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A239SR67 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/400065:CKV83_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A239SQZ7 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/400065:CKV83_RS08885 ^@ http://purl.uniprot.org/uniprot/A0A239SXN3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/400065:CKV83_RS00255 ^@ http://purl.uniprot.org/uniprot/A0A239SKT2 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/400065:CKV83_RS03740 ^@ http://purl.uniprot.org/uniprot/A0A239SQR7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/400065:CKV83_RS03875 ^@ http://purl.uniprot.org/uniprot/A0A239SRA8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family.|||Homotrimer.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/400065:CKV83_RS04045 ^@ http://purl.uniprot.org/uniprot/A0A239SR44 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/400065:CKV83_RS09840 ^@ http://purl.uniprot.org/uniprot/A0A239SZQ8 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/400065:CKV83_RS09160 ^@ http://purl.uniprot.org/uniprot/A0A239T0K4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/400065:CKV83_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A239STK8 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/400065:CKV83_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A239SN56 ^@ Similarity ^@ Belongs to the TelA family. http://togogenome.org/gene/400065:CKV83_RS00305 ^@ http://purl.uniprot.org/uniprot/A0A239SN08 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS03065 ^@ http://purl.uniprot.org/uniprot/A0A239SRI2 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/400065:CKV83_RS04155 ^@ http://purl.uniprot.org/uniprot/A0A239SRD7 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. NagD family. http://togogenome.org/gene/400065:CKV83_RS05030 ^@ http://purl.uniprot.org/uniprot/A0A239SSU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/400065:CKV83_RS03660 ^@ http://purl.uniprot.org/uniprot/A0A239SQZ4 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. http://togogenome.org/gene/400065:CKV83_RS04665 ^@ http://purl.uniprot.org/uniprot/A0A239SS38 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/400065:CKV83_RS02445 ^@ http://purl.uniprot.org/uniprot/A0A239SQV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS03110 ^@ http://purl.uniprot.org/uniprot/A0A239SRT6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS03120 ^@ http://purl.uniprot.org/uniprot/A0A239SR86 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase family. ParE type 2 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/400065:CKV83_RS03135 ^@ http://purl.uniprot.org/uniprot/A0A239SR96 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/400065:CKV83_RS02615 ^@ http://purl.uniprot.org/uniprot/A0A239SR51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS10695 ^@ http://purl.uniprot.org/uniprot/A0A239T1U2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the rhamnose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the interconversion of L-rhamnose and L-rhamnulose.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS08775 ^@ http://purl.uniprot.org/uniprot/A0A239SXC6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/400065:CKV83_RS06140 ^@ http://purl.uniprot.org/uniprot/A0A239SVM9 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/400065:CKV83_RS07425 ^@ http://purl.uniprot.org/uniprot/A0A239SW35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/400065:CKV83_RS06115 ^@ http://purl.uniprot.org/uniprot/A0A239STF6 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/400065:CKV83_RS08660 ^@ http://purl.uniprot.org/uniprot/A0A239SYX4 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS01300 ^@ http://purl.uniprot.org/uniprot/A0A239SP60 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A239SY03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/400065:CKV83_RS07735 ^@ http://purl.uniprot.org/uniprot/A0A239SVP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS10700 ^@ http://purl.uniprot.org/uniprot/A0A239T013 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aldolase class II family. RhaD subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS10200 ^@ http://purl.uniprot.org/uniprot/A0A239T053 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS03785 ^@ http://purl.uniprot.org/uniprot/A0A239SR60 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS05765 ^@ http://purl.uniprot.org/uniprot/A0A239ST23 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/400065:CKV83_RS00060 ^@ http://purl.uniprot.org/uniprot/A0A239SM74 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS08770 ^@ http://purl.uniprot.org/uniprot/A0A239SZ29 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/400065:CKV83_RS06295 ^@ http://purl.uniprot.org/uniprot/A0A239SUG7 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/400065:CKV83_RS02385 ^@ http://purl.uniprot.org/uniprot/A0A239SP31 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. CshA subfamily.|||Cytoplasm|||DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.|||Oligomerizes, may be a member of the RNA degradosome. http://togogenome.org/gene/400065:CKV83_RS04920 ^@ http://purl.uniprot.org/uniprot/A0A239SS33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS02985 ^@ http://purl.uniprot.org/uniprot/A0A239SRD5 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/400065:CKV83_RS09225 ^@ http://purl.uniprot.org/uniprot/A0A239T0B2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/400065:CKV83_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A239SWJ5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/400065:CKV83_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A239SKJ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS08100 ^@ http://purl.uniprot.org/uniprot/A0A239SWR9 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/400065:CKV83_RS03010 ^@ http://purl.uniprot.org/uniprot/A0A239SPI5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS04460 ^@ http://purl.uniprot.org/uniprot/A0A239SRW1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. HMG-CoA synthase family. http://togogenome.org/gene/400065:CKV83_RS02790 ^@ http://purl.uniprot.org/uniprot/A0A239SP91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/400065:CKV83_RS09925 ^@ http://purl.uniprot.org/uniprot/A0A239SZV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS00330 ^@ http://purl.uniprot.org/uniprot/A0A239SLG6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/400065:CKV83_RS09590 ^@ http://purl.uniprot.org/uniprot/A0A239T0S9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RpoE family.|||Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.|||RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors. http://togogenome.org/gene/400065:CKV83_RS09510 ^@ http://purl.uniprot.org/uniprot/A0A239T074 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS06085 ^@ http://purl.uniprot.org/uniprot/A0A239STC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arginine deiminase family.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS08025 ^@ http://purl.uniprot.org/uniprot/A0A239SW65 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/400065:CKV83_RS01625 ^@ http://purl.uniprot.org/uniprot/A0A239SN48 ^@ Similarity ^@ Belongs to the EutP/PduV family. http://togogenome.org/gene/400065:CKV83_RS08185 ^@ http://purl.uniprot.org/uniprot/A0A239SX57 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/400065:CKV83_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A239SWD6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/400065:CKV83_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A239SLM0 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/400065:CKV83_RS09245 ^@ http://purl.uniprot.org/uniprot/A0A239SZV8 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/400065:CKV83_RS08605 ^@ http://purl.uniprot.org/uniprot/A0A239SX38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/400065:CKV83_RS11190 ^@ http://purl.uniprot.org/uniprot/A0A239T331 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS05370 ^@ http://purl.uniprot.org/uniprot/A0A239SSK3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/400065:CKV83_RS09445 ^@ http://purl.uniprot.org/uniprot/A0A239SYF7 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/400065:CKV83_RS03960 ^@ http://purl.uniprot.org/uniprot/A0A239SQZ1 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/400065:CKV83_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A239STP5 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/400065:CKV83_RS08075 ^@ http://purl.uniprot.org/uniprot/A0A239SWC1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/400065:CKV83_RS09845 ^@ http://purl.uniprot.org/uniprot/A0A239SZQ6 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/400065:CKV83_RS09890 ^@ http://purl.uniprot.org/uniprot/A0A239SZ45 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A239SRY7 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A239SZX6 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/400065:CKV83_RS05035 ^@ http://purl.uniprot.org/uniprot/A0A239SS80 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/400065:CKV83_RS02940 ^@ http://purl.uniprot.org/uniprot/A0A239SPG4 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/400065:CKV83_RS05855 ^@ http://purl.uniprot.org/uniprot/A0A239SV32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HPr family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.|||P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity. http://togogenome.org/gene/400065:CKV83_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A239ST79 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS08905 ^@ http://purl.uniprot.org/uniprot/A0A239SZA7 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/400065:CKV83_RS04865 ^@ http://purl.uniprot.org/uniprot/A0A239SS77 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS01950 ^@ http://purl.uniprot.org/uniprot/A0A239SNJ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/400065:CKV83_RS09555 ^@ http://purl.uniprot.org/uniprot/A0A239SYY9 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/400065:CKV83_RS08365 ^@ http://purl.uniprot.org/uniprot/A0A239SWV4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS07415 ^@ http://purl.uniprot.org/uniprot/A0A239SVR0 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/400065:CKV83_RS06910 ^@ http://purl.uniprot.org/uniprot/A0A239SUK3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.|||Cell membrane|||Membrane|||Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. http://togogenome.org/gene/400065:CKV83_RS10635 ^@ http://purl.uniprot.org/uniprot/A0A239T0D4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS00325 ^@ http://purl.uniprot.org/uniprot/A0A239SLC2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/400065:CKV83_RS05640 ^@ http://purl.uniprot.org/uniprot/A0A239ST36 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/400065:CKV83_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A239SPZ5 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/400065:CKV83_RS03230 ^@ http://purl.uniprot.org/uniprot/A0A239SPN3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A239SPG3 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/400065:CKV83_RS02270 ^@ http://purl.uniprot.org/uniprot/A0A239SQN3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS06560 ^@ http://purl.uniprot.org/uniprot/A0A239SW02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS07375 ^@ http://purl.uniprot.org/uniprot/A0A239SXU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS03695 ^@ http://purl.uniprot.org/uniprot/A0A239SQK1 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/400065:CKV83_RS05885 ^@ http://purl.uniprot.org/uniprot/A0A239ST73 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/400065:CKV83_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A239SR31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/400065:CKV83_RS08420 ^@ http://purl.uniprot.org/uniprot/A0A239SYK5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/400065:CKV83_RS05560 ^@ http://purl.uniprot.org/uniprot/A0A239SUP3 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS11055 ^@ http://purl.uniprot.org/uniprot/A0A239T0F0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/400065:CKV83_RS02045 ^@ http://purl.uniprot.org/uniprot/A0A239SN53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS00810 ^@ http://purl.uniprot.org/uniprot/A0A239SM15 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/400065:CKV83_RS03715 ^@ http://purl.uniprot.org/uniprot/A0A239SR26 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/400065:CKV83_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A239ST48 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS07995 ^@ http://purl.uniprot.org/uniprot/A0A239SYD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS08425 ^@ http://purl.uniprot.org/uniprot/A0A239SWV0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/400065:CKV83_RS02705 ^@ http://purl.uniprot.org/uniprot/A0A239SQN1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS02325 ^@ http://purl.uniprot.org/uniprot/A0A239SNG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS08670 ^@ http://purl.uniprot.org/uniprot/A0A239SZE1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/400065:CKV83_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A239SR95 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/400065:CKV83_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A239SRY9 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/400065:CKV83_RS02155 ^@ http://purl.uniprot.org/uniprot/A0A239SNF6 ^@ Function|||Similarity ^@ Belongs to the mannonate dehydratase family.|||Catalyzes the dehydration of D-mannonate. http://togogenome.org/gene/400065:CKV83_RS06285 ^@ http://purl.uniprot.org/uniprot/A0A239STZ0 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/400065:CKV83_RS09070 ^@ http://purl.uniprot.org/uniprot/A0A239SXY1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/400065:CKV83_RS02545 ^@ http://purl.uniprot.org/uniprot/A0A239SQY9 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/400065:CKV83_RS05235 ^@ http://purl.uniprot.org/uniprot/A0A239SSF3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/400065:CKV83_RS04850 ^@ http://purl.uniprot.org/uniprot/A0A239SSK8 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/400065:CKV83_RS06020 ^@ http://purl.uniprot.org/uniprot/A0A239STK0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.|||Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS03870 ^@ http://purl.uniprot.org/uniprot/A0A239SQY5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/400065:CKV83_RS01015 ^@ http://purl.uniprot.org/uniprot/A0A239SNY5 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/400065:CKV83_RS05470 ^@ http://purl.uniprot.org/uniprot/A0A239STD4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/400065:CKV83_RS02660 ^@ http://purl.uniprot.org/uniprot/A0A239SR76 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/400065:CKV83_RS01525 ^@ http://purl.uniprot.org/uniprot/A0A239SMV4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/400065:CKV83_RS08525 ^@ http://purl.uniprot.org/uniprot/A0A239SWU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/400065:CKV83_RS07710 ^@ http://purl.uniprot.org/uniprot/A0A239SXJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS10560 ^@ http://purl.uniprot.org/uniprot/A0A239T1P4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS01080 ^@ http://purl.uniprot.org/uniprot/A0A239SLX8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/400065:CKV83_RS06520 ^@ http://purl.uniprot.org/uniprot/A0A239SW79 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/400065:CKV83_RS08215 ^@ http://purl.uniprot.org/uniprot/A0A239SWE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS01870 ^@ http://purl.uniprot.org/uniprot/A0A239SMZ3 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/400065:CKV83_RS00270 ^@ http://purl.uniprot.org/uniprot/A0A239SKW9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/400065:CKV83_RS00950 ^@ http://purl.uniprot.org/uniprot/A0A239SN89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/400065:CKV83_RS09685 ^@ http://purl.uniprot.org/uniprot/A0A239T0J2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS06050 ^@ http://purl.uniprot.org/uniprot/A0A239STJ7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/400065:CKV83_RS10490 ^@ http://purl.uniprot.org/uniprot/A0A239T0J5 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS06995 ^@ http://purl.uniprot.org/uniprot/A0A239SV51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A239SRV3 ^@ Function|||Similarity ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. http://togogenome.org/gene/400065:CKV83_RS07815 ^@ http://purl.uniprot.org/uniprot/A0A239SWH9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/400065:CKV83_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A239SNU5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PPase class C family.|||Binds 2 manganese ions per subunit.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS04335 ^@ http://purl.uniprot.org/uniprot/A0A239SS10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS00390 ^@ http://purl.uniprot.org/uniprot/A0A239SL20 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS10180 ^@ http://purl.uniprot.org/uniprot/A0A239T061 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/400065:CKV83_RS10435 ^@ http://purl.uniprot.org/uniprot/A0A239SZR2 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/400065:CKV83_RS02925 ^@ http://purl.uniprot.org/uniprot/A0A239SPE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS08200 ^@ http://purl.uniprot.org/uniprot/A0A239SWW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS06195 ^@ http://purl.uniprot.org/uniprot/A0A239SVQ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS05010 ^@ http://purl.uniprot.org/uniprot/A0A239SSV8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/400065:CKV83_RS01045 ^@ http://purl.uniprot.org/uniprot/A0A239SLT1 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/400065:CKV83_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A239SMY1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/400065:CKV83_RS06065 ^@ http://purl.uniprot.org/uniprot/A0A239SU22 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/400065:CKV83_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A239STF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/400065:CKV83_RS08910 ^@ http://purl.uniprot.org/uniprot/A0A239SY96 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/400065:CKV83_RS04875 ^@ http://purl.uniprot.org/uniprot/A0A239SSQ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A239SU75 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/400065:CKV83_RS01240 ^@ http://purl.uniprot.org/uniprot/A0A239SNP1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/400065:CKV83_RS04320 ^@ http://purl.uniprot.org/uniprot/A0A239STF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/400065:CKV83_RS02935 ^@ http://purl.uniprot.org/uniprot/A0A239SRB3 ^@ Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family. http://togogenome.org/gene/400065:CKV83_RS02140 ^@ http://purl.uniprot.org/uniprot/A0A239SNE9 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/400065:CKV83_RS09075 ^@ http://purl.uniprot.org/uniprot/A0A239SXW0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GdpP/PdeA phosphodiesterase family.|||Cell membrane|||For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.|||Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP). http://togogenome.org/gene/400065:CKV83_RS11125 ^@ http://purl.uniprot.org/uniprot/A0A239T0W4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S15 family.|||Cytoplasm|||Homodimer.|||Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. http://togogenome.org/gene/400065:CKV83_RS01480 ^@ http://purl.uniprot.org/uniprot/A0A239SMF6 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS08550 ^@ http://purl.uniprot.org/uniprot/A0A239SXQ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/400065:CKV83_RS04010 ^@ http://purl.uniprot.org/uniprot/A0A239SR18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS00320 ^@ http://purl.uniprot.org/uniprot/A0A239SKY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/400065:CKV83_RS05020 ^@ http://purl.uniprot.org/uniprot/A0A239SS66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/400065:CKV83_RS10550 ^@ http://purl.uniprot.org/uniprot/A0A239T2D6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/400065:CKV83_RS08275 ^@ http://purl.uniprot.org/uniprot/A0A239SWQ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GpsB family.|||Cytoplasm|||Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.|||Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA. http://togogenome.org/gene/400065:CKV83_RS04925 ^@ http://purl.uniprot.org/uniprot/A0A239SUH5 ^@ Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.|||Dephosphorylates CpsD. Involved in the regulation of capsular polysaccharide biosynthesis. http://togogenome.org/gene/400065:CKV83_RS04280 ^@ http://purl.uniprot.org/uniprot/A0A239STL7 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/400065:CKV83_RS08175 ^@ http://purl.uniprot.org/uniprot/A0A239SZ14 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/400065:CKV83_RS03290 ^@ http://purl.uniprot.org/uniprot/A0A239SQC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS10780 ^@ http://purl.uniprot.org/uniprot/A0A239T2D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS06680 ^@ http://purl.uniprot.org/uniprot/A0A239SUI7 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/400065:CKV83_RS00995 ^@ http://purl.uniprot.org/uniprot/A0A239SNP2 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/400065:CKV83_RS02340 ^@ http://purl.uniprot.org/uniprot/A0A239SNH2 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/400065:CKV83_RS03465 ^@ http://purl.uniprot.org/uniprot/A0A239SSE5 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/400065:CKV83_RS07660 ^@ http://purl.uniprot.org/uniprot/A0A239SXG9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. PolC subfamily.|||Cytoplasm|||Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/400065:CKV83_RS01755 ^@ http://purl.uniprot.org/uniprot/A0A239SMR6 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/400065:CKV83_RS05780 ^@ http://purl.uniprot.org/uniprot/A0A239ST99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS04405 ^@ http://purl.uniprot.org/uniprot/A0A239STJ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS09135 ^@ http://purl.uniprot.org/uniprot/A0A239SZP5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/400065:CKV83_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A239SSF8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS06950 ^@ http://purl.uniprot.org/uniprot/A0A239SX56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS03180 ^@ http://purl.uniprot.org/uniprot/A0A239SQ59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS05970 ^@ http://purl.uniprot.org/uniprot/A0A239STY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS10340 ^@ http://purl.uniprot.org/uniprot/A0A239T1W2 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/400065:CKV83_RS02050 ^@ http://purl.uniprot.org/uniprot/A0A239SPT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A239SS05 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/400065:CKV83_RS02715 ^@ http://purl.uniprot.org/uniprot/A0A239SPJ3 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/400065:CKV83_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A239SWP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/400065:CKV83_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A239SXW2 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS01900 ^@ http://purl.uniprot.org/uniprot/A0A239SNH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS11015 ^@ http://purl.uniprot.org/uniprot/A0A239T2L9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS08545 ^@ http://purl.uniprot.org/uniprot/A0A239SXG1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/400065:CKV83_RS01050 ^@ http://purl.uniprot.org/uniprot/A0A239SMD2 ^@ Function ^@ PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/400065:CKV83_RS08565 ^@ http://purl.uniprot.org/uniprot/A0A239SYS8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/400065:CKV83_RS09835 ^@ http://purl.uniprot.org/uniprot/A0A239SZG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Ycf16 family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS03895 ^@ http://purl.uniprot.org/uniprot/A0A239SST5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/400065:CKV83_RS01430 ^@ http://purl.uniprot.org/uniprot/A0A239SMC9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS07325 ^@ http://purl.uniprot.org/uniprot/A0A239SXD3 ^@ Similarity ^@ Belongs to the UPF0177 family. http://togogenome.org/gene/400065:CKV83_RS08305 ^@ http://purl.uniprot.org/uniprot/A0A239SYU7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/400065:CKV83_RS06745 ^@ http://purl.uniprot.org/uniprot/A0A239SWZ1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/400065:CKV83_RS04110 ^@ http://purl.uniprot.org/uniprot/A0A239SR02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS10765 ^@ http://purl.uniprot.org/uniprot/A0A239T1W8 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/400065:CKV83_RS06945 ^@ http://purl.uniprot.org/uniprot/A0A239SVC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS04125 ^@ http://purl.uniprot.org/uniprot/A0A239SR11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/400065:CKV83_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A239SV12 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS03240 ^@ http://purl.uniprot.org/uniprot/A0A239SPU0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS04315 ^@ http://purl.uniprot.org/uniprot/A0A239SRH1 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/400065:CKV83_RS01750 ^@ http://purl.uniprot.org/uniprot/A0A239SN86 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/400065:CKV83_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A239SPK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/400065:CKV83_RS07895 ^@ http://purl.uniprot.org/uniprot/A0A239SY66 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS00035 ^@ http://purl.uniprot.org/uniprot/A0A239SKL0 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/400065:CKV83_RS08045 ^@ http://purl.uniprot.org/uniprot/A0A239SWY8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/400065:CKV83_RS10120 ^@ http://purl.uniprot.org/uniprot/A0A239T1L8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS02555 ^@ http://purl.uniprot.org/uniprot/A0A239SNW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS00515 ^@ http://purl.uniprot.org/uniprot/A0A239SL44 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS01185 ^@ http://purl.uniprot.org/uniprot/A0A239SM28 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/400065:CKV83_RS01235 ^@ http://purl.uniprot.org/uniprot/A0A239SM62 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/400065:CKV83_RS04400 ^@ http://purl.uniprot.org/uniprot/A0A239SRK4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/400065:CKV83_RS05900 ^@ http://purl.uniprot.org/uniprot/A0A239STM7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS10980 ^@ http://purl.uniprot.org/uniprot/A0A239T0C1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS02090 ^@ http://purl.uniprot.org/uniprot/A0A239SN70 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A239SRH9 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/400065:CKV83_RS00355 ^@ http://purl.uniprot.org/uniprot/A0A239SKX1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/400065:CKV83_RS10745 ^@ http://purl.uniprot.org/uniprot/A0A239T0R0 ^@ Cofactor ^@ Binds 2 magnesium ions per subunit. http://togogenome.org/gene/400065:CKV83_RS08830 ^@ http://purl.uniprot.org/uniprot/A0A239SZN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS04540 ^@ http://purl.uniprot.org/uniprot/A0A239STG0 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS11065 ^@ http://purl.uniprot.org/uniprot/A0A239T2X4 ^@ Function ^@ Required for transformation and DNA binding. http://togogenome.org/gene/400065:CKV83_RS04820 ^@ http://purl.uniprot.org/uniprot/A0A239SSA6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/400065:CKV83_RS08410 ^@ http://purl.uniprot.org/uniprot/A0A239SXI9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/400065:CKV83_RS07480 ^@ http://purl.uniprot.org/uniprot/A0A239SVE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS01845 ^@ http://purl.uniprot.org/uniprot/A0A239SMY2 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/400065:CKV83_RS00135 ^@ http://purl.uniprot.org/uniprot/A0A239SKQ6 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/400065:CKV83_RS07025 ^@ http://purl.uniprot.org/uniprot/A0A239SUP9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcAL family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS01675 ^@ http://purl.uniprot.org/uniprot/A0A239SMU0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutB family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/400065:CKV83_RS06000 ^@ http://purl.uniprot.org/uniprot/A0A239STH4 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A239SRQ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A239SS53 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/400065:CKV83_RS08340 ^@ http://purl.uniprot.org/uniprot/A0A239SZ93 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/400065:CKV83_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A239SUP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family. YeeN subfamily.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS09885 ^@ http://purl.uniprot.org/uniprot/A0A239T0X3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS07175 ^@ http://purl.uniprot.org/uniprot/A0A239SVP2 ^@ Caution|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family. AlsE subfamily.|||Catalyzes the reversible epimerization of D-allulose 6-phosphate to D-fructose 6-phosphate. Can also catalyze with lower efficiency the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A239SVX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS09485 ^@ http://purl.uniprot.org/uniprot/A0A239SZ18 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/400065:CKV83_RS08655 ^@ http://purl.uniprot.org/uniprot/A0A239SXM0 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A239SWD8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/400065:CKV83_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A239SMT8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/400065:CKV83_RS00760 ^@ http://purl.uniprot.org/uniprot/A0A239SLG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS04935 ^@ http://purl.uniprot.org/uniprot/A0A239SSP5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS08590 ^@ http://purl.uniprot.org/uniprot/A0A239SXT1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/400065:CKV83_RS08090 ^@ http://purl.uniprot.org/uniprot/A0A239SWD3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/400065:CKV83_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A239SWZ7 ^@ Function ^@ Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function. http://togogenome.org/gene/400065:CKV83_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A239SRV1 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/400065:CKV83_RS05110 ^@ http://purl.uniprot.org/uniprot/A0A239SSB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS01700 ^@ http://purl.uniprot.org/uniprot/A0A239SPB4 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/400065:CKV83_RS01760 ^@ http://purl.uniprot.org/uniprot/A0A239SQ20 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/400065:CKV83_RS10245 ^@ http://purl.uniprot.org/uniprot/A0A239SZZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/400065:CKV83_RS05895 ^@ http://purl.uniprot.org/uniprot/A0A239SVD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CitD family.|||Covalent carrier of the coenzyme of citrate lyase.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6. http://togogenome.org/gene/400065:CKV83_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A239SX75 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/400065:CKV83_RS06345 ^@ http://purl.uniprot.org/uniprot/A0A239STR8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/400065:CKV83_RS09580 ^@ http://purl.uniprot.org/uniprot/A0A239SYK9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/400065:CKV83_RS00540 ^@ http://purl.uniprot.org/uniprot/A0A239SN25 ^@ Similarity|||Subunit ^@ Belongs to the LacAB/RpiB family.|||Heteromultimeric protein consisting of LacA and LacB. http://togogenome.org/gene/400065:CKV83_RS01930 ^@ http://purl.uniprot.org/uniprot/A0A239SPM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/400065:CKV83_RS07795 ^@ http://purl.uniprot.org/uniprot/A0A239SVY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS05750 ^@ http://purl.uniprot.org/uniprot/A0A239STQ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS09815 ^@ http://purl.uniprot.org/uniprot/A0A239T183 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/400065:CKV83_RS06920 ^@ http://purl.uniprot.org/uniprot/A0A239SUS3 ^@ Similarity ^@ Belongs to the polysaccharide lyase 8 family. http://togogenome.org/gene/400065:CKV83_RS06540 ^@ http://purl.uniprot.org/uniprot/A0A239SU13 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS02265 ^@ http://purl.uniprot.org/uniprot/A0A239SNE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS05955 ^@ http://purl.uniprot.org/uniprot/A0A239SVF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS10775 ^@ http://purl.uniprot.org/uniprot/A0A239T0U6 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/400065:CKV83_RS06630 ^@ http://purl.uniprot.org/uniprot/A0A239SUG6 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/400065:CKV83_RS03070 ^@ http://purl.uniprot.org/uniprot/A0A239SPN2 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/400065:CKV83_RS00430 ^@ http://purl.uniprot.org/uniprot/A0A239SL35 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/400065:CKV83_RS07165 ^@ http://purl.uniprot.org/uniprot/A0A239SV30 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/400065:CKV83_RS02630 ^@ http://purl.uniprot.org/uniprot/A0A239SPF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS06585 ^@ http://purl.uniprot.org/uniprot/A0A239SWR0 ^@ Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family. http://togogenome.org/gene/400065:CKV83_RS05515 ^@ http://purl.uniprot.org/uniprot/A0A239STD3 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/400065:CKV83_RS06330 ^@ http://purl.uniprot.org/uniprot/A0A239SUF9 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/400065:CKV83_RS06075 ^@ http://purl.uniprot.org/uniprot/A0A239STD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. http://togogenome.org/gene/400065:CKV83_RS01475 ^@ http://purl.uniprot.org/uniprot/A0A239SNZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/400065:CKV83_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A239SPL1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/400065:CKV83_RS06490 ^@ http://purl.uniprot.org/uniprot/A0A239SUN7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/400065:CKV83_RS06280 ^@ http://purl.uniprot.org/uniprot/A0A239SVW4 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/400065:CKV83_RS06095 ^@ http://purl.uniprot.org/uniprot/A0A239STL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/400065:CKV83_RS08595 ^@ http://purl.uniprot.org/uniprot/A0A239SWY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/400065:CKV83_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A239SRU2 ^@ Caution|||Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS11200 ^@ http://purl.uniprot.org/uniprot/A0A239T2U0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A239SL83 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. LacC subfamily.|||Belongs to the carbohydrate kinase pfkB family. http://togogenome.org/gene/400065:CKV83_RS10485 ^@ http://purl.uniprot.org/uniprot/A0A239SZT6 ^@ Similarity|||Subunit ^@ Belongs to the UPF0237 family.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS03355 ^@ http://purl.uniprot.org/uniprot/A0A239SPV8 ^@ Similarity ^@ Belongs to the PRORSD1 family. http://togogenome.org/gene/400065:CKV83_RS11025 ^@ http://purl.uniprot.org/uniprot/A0A239T271 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/400065:CKV83_RS01515 ^@ http://purl.uniprot.org/uniprot/A0A239SMJ8 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/400065:CKV83_RS06445 ^@ http://purl.uniprot.org/uniprot/A0A239SWI4 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/400065:CKV83_RS02675 ^@ http://purl.uniprot.org/uniprot/A0A239SPH8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS08860 ^@ http://purl.uniprot.org/uniprot/A0A239SY72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/400065:CKV83_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A239SLL6 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/400065:CKV83_RS08475 ^@ http://purl.uniprot.org/uniprot/A0A239SX12 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/400065:CKV83_RS08495 ^@ http://purl.uniprot.org/uniprot/A0A239SXM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/400065:CKV83_RS08190 ^@ http://purl.uniprot.org/uniprot/A0A239SWF6 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/400065:CKV83_RS00660 ^@ http://purl.uniprot.org/uniprot/A0A239SLV5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/400065:CKV83_RS09695 ^@ http://purl.uniprot.org/uniprot/A0A239T102 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS00850 ^@ http://purl.uniprot.org/uniprot/A0A239SLX7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A239SX35 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. CshB subfamily.|||Cytoplasm|||Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. http://togogenome.org/gene/400065:CKV83_RS07330 ^@ http://purl.uniprot.org/uniprot/A0A239SVB6 ^@ Similarity ^@ Belongs to the UPF0177 family. http://togogenome.org/gene/400065:CKV83_RS04815 ^@ http://purl.uniprot.org/uniprot/A0A239SU27 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/400065:CKV83_RS08205 ^@ http://purl.uniprot.org/uniprot/A0A239SX70 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A239SRP2 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/400065:CKV83_RS10110 ^@ http://purl.uniprot.org/uniprot/A0A239SZE2 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/400065:CKV83_RS02130 ^@ http://purl.uniprot.org/uniprot/A0A239SNE5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS06405 ^@ http://purl.uniprot.org/uniprot/A0A239SWG7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A239SSX9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/400065:CKV83_RS03745 ^@ http://purl.uniprot.org/uniprot/A0A239SSA7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS08855 ^@ http://purl.uniprot.org/uniprot/A0A239SY74 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/400065:CKV83_RS05770 ^@ http://purl.uniprot.org/uniprot/A0A239SVM5 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/400065:CKV83_RS04940 ^@ http://purl.uniprot.org/uniprot/A0A239SS42 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/400065:CKV83_RS00820 ^@ http://purl.uniprot.org/uniprot/A0A239SLJ4 ^@ Similarity ^@ Belongs to the UPF0177 family. http://togogenome.org/gene/400065:CKV83_RS01830 ^@ http://purl.uniprot.org/uniprot/A0A239SMV7 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/400065:CKV83_RS02290 ^@ http://purl.uniprot.org/uniprot/A0A239SNF2 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/400065:CKV83_RS03410 ^@ http://purl.uniprot.org/uniprot/A0A239SSB2 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/400065:CKV83_RS05350 ^@ http://purl.uniprot.org/uniprot/A0A239SSR7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/400065:CKV83_RS09710 ^@ http://purl.uniprot.org/uniprot/A0A239SZH4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A239SST9 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/400065:CKV83_RS03680 ^@ http://purl.uniprot.org/uniprot/A0A239SQJ3 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/400065:CKV83_RS09500 ^@ http://purl.uniprot.org/uniprot/A0A239SYG2 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/400065:CKV83_RS07245 ^@ http://purl.uniprot.org/uniprot/A0A239SV20 ^@ Subcellular Location Annotation ^@ cell wall http://togogenome.org/gene/400065:CKV83_RS00225 ^@ http://purl.uniprot.org/uniprot/A0A239SKR2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS03690 ^@ http://purl.uniprot.org/uniprot/A0A239SQL3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/400065:CKV83_RS10035 ^@ http://purl.uniprot.org/uniprot/A0A239SZB1 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/400065:CKV83_RS02890 ^@ http://purl.uniprot.org/uniprot/A0A239SPS2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS08540 ^@ http://purl.uniprot.org/uniprot/A0A239SZK2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/400065:CKV83_RS08980 ^@ http://purl.uniprot.org/uniprot/A0A239SYD7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A239SXA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS00250 ^@ http://purl.uniprot.org/uniprot/A0A239SKV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/400065:CKV83_RS01215 ^@ http://purl.uniprot.org/uniprot/A0A239SM52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS02765 ^@ http://purl.uniprot.org/uniprot/A0A239SPM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArsC family. Spx subfamily.|||Cytoplasm|||Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.|||Interacts with the C-terminal domain of the alpha subunit of the RNAP. http://togogenome.org/gene/400065:CKV83_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A239ST63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/400065:CKV83_RS06160 ^@ http://purl.uniprot.org/uniprot/A0A239STG6 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/400065:CKV83_RS09210 ^@ http://purl.uniprot.org/uniprot/A0A239T0A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS02025 ^@ http://purl.uniprot.org/uniprot/A0A239SN95 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/400065:CKV83_RS07355 ^@ http://purl.uniprot.org/uniprot/A0A239SV75 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs.|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/400065:CKV83_RS00420 ^@ http://purl.uniprot.org/uniprot/A0A239SN79 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/400065:CKV83_RS00110 ^@ http://purl.uniprot.org/uniprot/A0A239SKP4 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/400065:CKV83_RS07495 ^@ http://purl.uniprot.org/uniprot/A0A239SY22 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS08580 ^@ http://purl.uniprot.org/uniprot/A0A239SXI0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/400065:CKV83_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A239SPG9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/400065:CKV83_RS02425 ^@ http://purl.uniprot.org/uniprot/A0A239SQK9 ^@ Similarity ^@ Belongs to the UPF0213 family. http://togogenome.org/gene/400065:CKV83_RS10580 ^@ http://purl.uniprot.org/uniprot/A0A239T0B7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS01060 ^@ http://purl.uniprot.org/uniprot/A0A239SLW0 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/400065:CKV83_RS04290 ^@ http://purl.uniprot.org/uniprot/A0A239SRW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS06580 ^@ http://purl.uniprot.org/uniprot/A0A239SUT1 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/400065:CKV83_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A239SW59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpA family.|||Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Cytoplasm|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/400065:CKV83_RS04530 ^@ http://purl.uniprot.org/uniprot/A0A239STQ5 ^@ Similarity ^@ Belongs to the cycloisomerase 2 family. http://togogenome.org/gene/400065:CKV83_RS06120 ^@ http://purl.uniprot.org/uniprot/A0A239SVM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS02415 ^@ http://purl.uniprot.org/uniprot/A0A239SNQ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.|||Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS09855 ^@ http://purl.uniprot.org/uniprot/A0A239T0V4 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/400065:CKV83_RS10205 ^@ http://purl.uniprot.org/uniprot/A0A239SZH9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/400065:CKV83_RS08945 ^@ http://purl.uniprot.org/uniprot/A0A239SZC6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 36 family. http://togogenome.org/gene/400065:CKV83_RS00400 ^@ http://purl.uniprot.org/uniprot/A0A239SKZ0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/400065:CKV83_RS09895 ^@ http://purl.uniprot.org/uniprot/A0A239T1C9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS01250 ^@ http://purl.uniprot.org/uniprot/A0A239SPB6 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/400065:CKV83_RS11545 ^@ http://purl.uniprot.org/uniprot/A0A239SS78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS07470 ^@ http://purl.uniprot.org/uniprot/A0A239SW31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS05850 ^@ http://purl.uniprot.org/uniprot/A0A239STL0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/400065:CKV83_RS03160 ^@ http://purl.uniprot.org/uniprot/A0A239SRB0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/400065:CKV83_RS03920 ^@ http://purl.uniprot.org/uniprot/A0A239SSJ5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/400065:CKV83_RS10170 ^@ http://purl.uniprot.org/uniprot/A0A239T187 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/400065:CKV83_RS01085 ^@ http://purl.uniprot.org/uniprot/A0A239SNG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS01715 ^@ http://purl.uniprot.org/uniprot/A0A239SPQ9 ^@ Function|||Similarity ^@ Belongs to the PduL family.|||Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. http://togogenome.org/gene/400065:CKV83_RS06135 ^@ http://purl.uniprot.org/uniprot/A0A239STG4 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/400065:CKV83_RS06965 ^@ http://purl.uniprot.org/uniprot/A0A239SVD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A239SQN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS06575 ^@ http://purl.uniprot.org/uniprot/A0A239SUE0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS05645 ^@ http://purl.uniprot.org/uniprot/A0A239STL3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/400065:CKV83_RS08110 ^@ http://purl.uniprot.org/uniprot/A0A239SX25 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/400065:CKV83_RS05595 ^@ http://purl.uniprot.org/uniprot/A0A239SVE4 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS05345 ^@ http://purl.uniprot.org/uniprot/A0A239SUG0 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A239ST76 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/400065:CKV83_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A239SN46 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/400065:CKV83_RS06665 ^@ http://purl.uniprot.org/uniprot/A0A239SUG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS03590 ^@ http://purl.uniprot.org/uniprot/A0A239SQ83 ^@ Similarity ^@ Belongs to the UPF0177 family. http://togogenome.org/gene/400065:CKV83_RS07740 ^@ http://purl.uniprot.org/uniprot/A0A239SXW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS05890 ^@ http://purl.uniprot.org/uniprot/A0A239STX8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6.|||Represents a citryl-ACP lyase. http://togogenome.org/gene/400065:CKV83_RS04255 ^@ http://purl.uniprot.org/uniprot/A0A239SRF0 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS05170 ^@ http://purl.uniprot.org/uniprot/A0A239SU93 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/400065:CKV83_RS00865 ^@ http://purl.uniprot.org/uniprot/A0A239SNQ5 ^@ Similarity ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. http://togogenome.org/gene/400065:CKV83_RS00470 ^@ http://purl.uniprot.org/uniprot/A0A239SL55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS00310 ^@ http://purl.uniprot.org/uniprot/A0A239SKV3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Homotetramer. http://togogenome.org/gene/400065:CKV83_RS10420 ^@ http://purl.uniprot.org/uniprot/A0A239SZK7 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/400065:CKV83_RS07635 ^@ http://purl.uniprot.org/uniprot/A0A239SVX6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/400065:CKV83_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A239SWM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/400065:CKV83_RS01630 ^@ http://purl.uniprot.org/uniprot/A0A239SMM5 ^@ Function ^@ Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/400065:CKV83_RS01945 ^@ http://purl.uniprot.org/uniprot/A0A239SN58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/400065:CKV83_RS10440 ^@ http://purl.uniprot.org/uniprot/A0A239T296 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/400065:CKV83_RS04565 ^@ http://purl.uniprot.org/uniprot/A0A239STG9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS07155 ^@ http://purl.uniprot.org/uniprot/A0A239SUW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS10280 ^@ http://purl.uniprot.org/uniprot/A0A239T1C8 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/400065:CKV83_RS01640 ^@ http://purl.uniprot.org/uniprot/A0A239SN55 ^@ Similarity ^@ Belongs to the CobT family. http://togogenome.org/gene/400065:CKV83_RS08235 ^@ http://purl.uniprot.org/uniprot/A0A239SYQ5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpB RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpA.|||Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS01025 ^@ http://purl.uniprot.org/uniprot/A0A239SLT9 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/400065:CKV83_RS01485 ^@ http://purl.uniprot.org/uniprot/A0A239SMZ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/400065:CKV83_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A239SPN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/400065:CKV83_RS04015 ^@ http://purl.uniprot.org/uniprot/A0A239SQV4 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/400065:CKV83_RS09290 ^@ http://purl.uniprot.org/uniprot/A0A239SYM4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/400065:CKV83_RS02420 ^@ http://purl.uniprot.org/uniprot/A0A239SP46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS10425 ^@ http://purl.uniprot.org/uniprot/A0A239SZK7 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/400065:CKV83_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A239SNL8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/400065:CKV83_RS06475 ^@ http://purl.uniprot.org/uniprot/A0A239SU01 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS09790 ^@ http://purl.uniprot.org/uniprot/A0A239SYY8 ^@ Similarity ^@ Belongs to the peptidase S1B family. http://togogenome.org/gene/400065:CKV83_RS10025 ^@ http://purl.uniprot.org/uniprot/A0A239SZZ9 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/400065:CKV83_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A239SSK6 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family.|||Homohexamer. http://togogenome.org/gene/400065:CKV83_RS06730 ^@ http://purl.uniprot.org/uniprot/A0A239SUB5 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/400065:CKV83_RS10040 ^@ http://purl.uniprot.org/uniprot/A0A239T1V0 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/400065:CKV83_RS09825 ^@ http://purl.uniprot.org/uniprot/A0A239SZ06 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the MecA family.|||Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.|||Homodimer.|||The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC. http://togogenome.org/gene/400065:CKV83_RS07690 ^@ http://purl.uniprot.org/uniprot/A0A239SW09 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/400065:CKV83_RS09090 ^@ http://purl.uniprot.org/uniprot/A0A239SXU0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS10285 ^@ http://purl.uniprot.org/uniprot/A0A239SZL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS08600 ^@ http://purl.uniprot.org/uniprot/A0A239SYU6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/400065:CKV83_RS01175 ^@ http://purl.uniprot.org/uniprot/A0A239SNY7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/400065:CKV83_RS05115 ^@ http://purl.uniprot.org/uniprot/A0A239SUR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS07475 ^@ http://purl.uniprot.org/uniprot/A0A239SVF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS04950 ^@ http://purl.uniprot.org/uniprot/A0A239SSH5 ^@ Similarity ^@ Belongs to the UPF0342 family. http://togogenome.org/gene/400065:CKV83_RS01855 ^@ http://purl.uniprot.org/uniprot/A0A239SPX6 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/400065:CKV83_RS06515 ^@ http://purl.uniprot.org/uniprot/A0A239SU20 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/400065:CKV83_RS03615 ^@ http://purl.uniprot.org/uniprot/A0A239SS29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS09100 ^@ http://purl.uniprot.org/uniprot/A0A239SXZ5 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/400065:CKV83_RS07125 ^@ http://purl.uniprot.org/uniprot/A0A239SX20 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS08930 ^@ http://purl.uniprot.org/uniprot/A0A239SXK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS07070 ^@ http://purl.uniprot.org/uniprot/A0A239SVI0 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/400065:CKV83_RS08630 ^@ http://purl.uniprot.org/uniprot/A0A239SXU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MrnC RNase family.|||Cytoplasm|||Homodimer.|||Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. http://togogenome.org/gene/400065:CKV83_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A239SLN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS08530 ^@ http://purl.uniprot.org/uniprot/A0A239SYR1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/400065:CKV83_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A239SMD9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/400065:CKV83_RS10925 ^@ http://purl.uniprot.org/uniprot/A0A239T099 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/400065:CKV83_RS10075 ^@ http://purl.uniprot.org/uniprot/A0A239SZH6 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/400065:CKV83_RS09095 ^@ http://purl.uniprot.org/uniprot/A0A239T035 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/400065:CKV83_RS07350 ^@ http://purl.uniprot.org/uniprot/A0A239SX39 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/400065:CKV83_RS00965 ^@ http://purl.uniprot.org/uniprot/A0A239SN99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/400065:CKV83_RS09960 ^@ http://purl.uniprot.org/uniprot/A0A239T1G4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/400065:CKV83_RS05000 ^@ http://purl.uniprot.org/uniprot/A0A239SSD6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/400065:CKV83_RS05465 ^@ http://purl.uniprot.org/uniprot/A0A239SSW2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/400065:CKV83_RS10620 ^@ http://purl.uniprot.org/uniprot/A0A239SZZ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS11035 ^@ http://purl.uniprot.org/uniprot/A0A239T140 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS00375 ^@ http://purl.uniprot.org/uniprot/A0A239SN59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS03305 ^@ http://purl.uniprot.org/uniprot/A0A239SRJ6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/400065:CKV83_RS10215 ^@ http://purl.uniprot.org/uniprot/A0A239T1P6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS09495 ^@ http://purl.uniprot.org/uniprot/A0A239T060 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS04785 ^@ http://purl.uniprot.org/uniprot/A0A239SRX5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS00650 ^@ http://purl.uniprot.org/uniprot/A0A239SLC7 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS06235 ^@ http://purl.uniprot.org/uniprot/A0A239STN4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/400065:CKV83_RS05615 ^@ http://purl.uniprot.org/uniprot/A0A239SSV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A239SLQ5 ^@ Similarity|||Subunit ^@ Belongs to the LacAB/RpiB family.|||Heteromultimeric protein consisting of LacA and LacB. http://togogenome.org/gene/400065:CKV83_RS01775 ^@ http://purl.uniprot.org/uniprot/A0A239SMU5 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/400065:CKV83_RS05880 ^@ http://purl.uniprot.org/uniprot/A0A239STV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:citrate (SCF) symporter family.|||Cell membrane http://togogenome.org/gene/400065:CKV83_RS08295 ^@ http://purl.uniprot.org/uniprot/A0A239SYE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0291 family.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS00460 ^@ http://purl.uniprot.org/uniprot/A0A239SL50 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/400065:CKV83_RS07860 ^@ http://purl.uniprot.org/uniprot/A0A239SVV0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/400065:CKV83_RS06725 ^@ http://purl.uniprot.org/uniprot/A0A239SV50 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/400065:CKV83_RS09420 ^@ http://purl.uniprot.org/uniprot/A0A239SYX8 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/400065:CKV83_RS01140 ^@ http://purl.uniprot.org/uniprot/A0A239SMB4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS01210 ^@ http://purl.uniprot.org/uniprot/A0A239SP05 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 32 family.|||Cytoplasm|||Enables the bacterium to metabolize sucrose as a sole carbon source. http://togogenome.org/gene/400065:CKV83_RS00955 ^@ http://purl.uniprot.org/uniprot/A0A239SLP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/400065:CKV83_RS07405 ^@ http://purl.uniprot.org/uniprot/A0A239SVA9 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/400065:CKV83_RS10070 ^@ http://purl.uniprot.org/uniprot/A0A239SZ89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A239SLC3 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/400065:CKV83_RS10210 ^@ http://purl.uniprot.org/uniprot/A0A239T072 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/400065:CKV83_RS01895 ^@ http://purl.uniprot.org/uniprot/A0A239SN03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS09130 ^@ http://purl.uniprot.org/uniprot/A0A239SXT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS07805 ^@ http://purl.uniprot.org/uniprot/A0A239SYF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A239SU28 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS08710 ^@ http://purl.uniprot.org/uniprot/A0A239SXQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS10885 ^@ http://purl.uniprot.org/uniprot/A0A239T029 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS05125 ^@ http://purl.uniprot.org/uniprot/A0A239SSP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS03980 ^@ http://purl.uniprot.org/uniprot/A0A239SQT3 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/400065:CKV83_RS08615 ^@ http://purl.uniprot.org/uniprot/A0A239SZP0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/400065:CKV83_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A239SNU1 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/400065:CKV83_RS05950 ^@ http://purl.uniprot.org/uniprot/A0A239SVV1 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS07055 ^@ http://purl.uniprot.org/uniprot/A0A239SUW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/400065:CKV83_RS00735 ^@ http://purl.uniprot.org/uniprot/A0A239SLF1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS04775 ^@ http://purl.uniprot.org/uniprot/A0A239SS40 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/400065:CKV83_RS03755 ^@ http://purl.uniprot.org/uniprot/A0A239SSU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS05675 ^@ http://purl.uniprot.org/uniprot/A0A239SV25 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/400065:CKV83_RS09215 ^@ http://purl.uniprot.org/uniprot/A0A239SZT5 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/400065:CKV83_RS03205 ^@ http://purl.uniprot.org/uniprot/A0A239SQ74 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/400065:CKV83_RS06525 ^@ http://purl.uniprot.org/uniprot/A0A239SUB1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/400065:CKV83_RS05210 ^@ http://purl.uniprot.org/uniprot/A0A239SUK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. AddA subfamily.|||Heterodimer of AddA and AddB/RexB.|||The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities. http://togogenome.org/gene/400065:CKV83_RS00890 ^@ http://purl.uniprot.org/uniprot/A0A239SNR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS08940 ^@ http://purl.uniprot.org/uniprot/A0A239SXH1 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/400065:CKV83_RS04985 ^@ http://purl.uniprot.org/uniprot/A0A239SS62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LTA synthase family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS10525 ^@ http://purl.uniprot.org/uniprot/A0A239T234 ^@ Similarity ^@ Belongs to the SIS family. AgaS subfamily. http://togogenome.org/gene/400065:CKV83_RS08480 ^@ http://purl.uniprot.org/uniprot/A0A239SWY0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/400065:CKV83_RS06175 ^@ http://purl.uniprot.org/uniprot/A0A239SW39 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS01920 ^@ http://purl.uniprot.org/uniprot/A0A239SMZ6 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/400065:CKV83_RS05830 ^@ http://purl.uniprot.org/uniprot/A0A239SV18 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/400065:CKV83_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A239SNW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS08975 ^@ http://purl.uniprot.org/uniprot/A0A239SY47 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS02750 ^@ http://purl.uniprot.org/uniprot/A0A239SP16 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS00640 ^@ http://purl.uniprot.org/uniprot/A0A239SL98 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS08685 ^@ http://purl.uniprot.org/uniprot/A0A239SZF2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/400065:CKV83_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A239SV62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS05525 ^@ http://purl.uniprot.org/uniprot/A0A239SUW4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS00945 ^@ http://purl.uniprot.org/uniprot/A0A239SLM9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/400065:CKV83_RS08370 ^@ http://purl.uniprot.org/uniprot/A0A239SWS0 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/400065:CKV83_RS01225 ^@ http://purl.uniprot.org/uniprot/A0A239SM33 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/400065:CKV83_RS03350 ^@ http://purl.uniprot.org/uniprot/A0A239SQF5 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/400065:CKV83_RS07140 ^@ http://purl.uniprot.org/uniprot/A0A239SVM4 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS05330 ^@ http://purl.uniprot.org/uniprot/A0A239SSK2 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/400065:CKV83_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A239SPB0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/400065:CKV83_RS09525 ^@ http://purl.uniprot.org/uniprot/A0A239SYK8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS10520 ^@ http://purl.uniprot.org/uniprot/A0A239T0J8 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/400065:CKV83_RS03060 ^@ http://purl.uniprot.org/uniprot/A0A239SQ04 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/400065:CKV83_RS00755 ^@ http://purl.uniprot.org/uniprot/A0A239SLU1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EzrA family.|||Cell membrane|||Membrane|||Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization. http://togogenome.org/gene/400065:CKV83_RS03420 ^@ http://purl.uniprot.org/uniprot/A0A239SQL2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS07115 ^@ http://purl.uniprot.org/uniprot/A0A239SVH9 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/400065:CKV83_RS04285 ^@ http://purl.uniprot.org/uniprot/A0A239SRL5 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/400065:CKV83_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A239SQ07 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS07280 ^@ http://purl.uniprot.org/uniprot/A0A239SV35 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/400065:CKV83_RS10515 ^@ http://purl.uniprot.org/uniprot/A0A239SZU0 ^@ Similarity ^@ Belongs to the aldolase LacD family. http://togogenome.org/gene/400065:CKV83_RS05255 ^@ http://purl.uniprot.org/uniprot/A0A239ST60 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS00125 ^@ http://purl.uniprot.org/uniprot/A0A239SMS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/400065:CKV83_RS10480 ^@ http://purl.uniprot.org/uniprot/A0A239T0F8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS01470 ^@ http://purl.uniprot.org/uniprot/A0A239SMD1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/400065:CKV83_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A239SSL5 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/400065:CKV83_RS08635 ^@ http://purl.uniprot.org/uniprot/A0A239SX05 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/400065:CKV83_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A239SLN9 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/400065:CKV83_RS05180 ^@ http://purl.uniprot.org/uniprot/A0A239SUW6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/400065:CKV83_RS10325 ^@ http://purl.uniprot.org/uniprot/A0A239SZQ9 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/400065:CKV83_RS06220 ^@ http://purl.uniprot.org/uniprot/A0A239STJ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 'phage' integrase family. XerD-like subfamily.|||Cytoplasm|||Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site. http://togogenome.org/gene/400065:CKV83_RS03515 ^@ http://purl.uniprot.org/uniprot/A0A239SQA7 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/400065:CKV83_RS00405 ^@ http://purl.uniprot.org/uniprot/A0A239SMM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS08740 ^@ http://purl.uniprot.org/uniprot/A0A239SY04 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/400065:CKV83_RS01935 ^@ http://purl.uniprot.org/uniprot/A0A239SN57 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/400065:CKV83_RS08390 ^@ http://purl.uniprot.org/uniprot/A0A239SWR6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/400065:CKV83_RS06125 ^@ http://purl.uniprot.org/uniprot/A0A239STP7 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS03530 ^@ http://purl.uniprot.org/uniprot/A0A239SQS4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/400065:CKV83_RS06035 ^@ http://purl.uniprot.org/uniprot/A0A239SVI1 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS06545 ^@ http://purl.uniprot.org/uniprot/A0A239SUB9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS04615 ^@ http://purl.uniprot.org/uniprot/A0A239SRP3 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/400065:CKV83_RS06690 ^@ http://purl.uniprot.org/uniprot/A0A239SV26 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/400065:CKV83_RS06435 ^@ http://purl.uniprot.org/uniprot/A0A239SU62 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/400065:CKV83_RS00360 ^@ http://purl.uniprot.org/uniprot/A0A239SL07 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/400065:CKV83_RS03190 ^@ http://purl.uniprot.org/uniprot/A0A239SRQ1 ^@ Subcellular Location Annotation ^@ Cell surface http://togogenome.org/gene/400065:CKV83_RS10845 ^@ http://purl.uniprot.org/uniprot/A0A239T063 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/400065:CKV83_RS04340 ^@ http://purl.uniprot.org/uniprot/A0A239STG8 ^@ Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone. http://togogenome.org/gene/400065:CKV83_RS03775 ^@ http://purl.uniprot.org/uniprot/A0A239SSV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS02920 ^@ http://purl.uniprot.org/uniprot/A0A239SPE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS09250 ^@ http://purl.uniprot.org/uniprot/A0A239SY30 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/400065:CKV83_RS04620 ^@ http://purl.uniprot.org/uniprot/A0A239SRW0 ^@ Function|||Similarity|||Subunit ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Homodimer and homohexamer; in equilibrium.|||Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. http://togogenome.org/gene/400065:CKV83_RS09120 ^@ http://purl.uniprot.org/uniprot/A0A239SYL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the energy-coupling factor EcfT family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).|||Membrane|||Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. http://togogenome.org/gene/400065:CKV83_RS10860 ^@ http://purl.uniprot.org/uniprot/A0A239T0L4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS06275 ^@ http://purl.uniprot.org/uniprot/A0A239SUF8 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/400065:CKV83_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A239SPX3 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/400065:CKV83_RS05300 ^@ http://purl.uniprot.org/uniprot/A0A239SSQ7 ^@ Function|||Similarity|||Subunit ^@ Associates with stalled 50S ribosomal subunits.|||Belongs to the NEMF family.|||Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. http://togogenome.org/gene/400065:CKV83_RS08750 ^@ http://purl.uniprot.org/uniprot/A0A239SXF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS01690 ^@ http://purl.uniprot.org/uniprot/A0A239SN77 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/400065:CKV83_RS09425 ^@ http://purl.uniprot.org/uniprot/A0A239SY61 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/400065:CKV83_RS01805 ^@ http://purl.uniprot.org/uniprot/A0A239SMZ1 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/400065:CKV83_RS07990 ^@ http://purl.uniprot.org/uniprot/A0A239SW49 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/400065:CKV83_RS07000 ^@ http://purl.uniprot.org/uniprot/A0A239SWI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS07380 ^@ http://purl.uniprot.org/uniprot/A0A239SVP1 ^@ Similarity ^@ Belongs to the UPF0340 family. http://togogenome.org/gene/400065:CKV83_RS03115 ^@ http://purl.uniprot.org/uniprot/A0A239SPQ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/400065:CKV83_RS03195 ^@ http://purl.uniprot.org/uniprot/A0A239SPS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-C family. DnaE subfamily.|||Cytoplasm|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase. http://togogenome.org/gene/400065:CKV83_RS06925 ^@ http://purl.uniprot.org/uniprot/A0A239SUQ0 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/400065:CKV83_RS08325 ^@ http://purl.uniprot.org/uniprot/A0A239SZ85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/400065:CKV83_RS03540 ^@ http://purl.uniprot.org/uniprot/A0A239SSI7 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/400065:CKV83_RS01925 ^@ http://purl.uniprot.org/uniprot/A0A239SN34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS00435 ^@ http://purl.uniprot.org/uniprot/A0A239SLG9 ^@ Function|||Similarity|||Subunit ^@ In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.|||Monomer.|||Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine. http://togogenome.org/gene/400065:CKV83_RS07490 ^@ http://purl.uniprot.org/uniprot/A0A239SVI3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/400065:CKV83_RS07290 ^@ http://purl.uniprot.org/uniprot/A0A239SV96 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS02795 ^@ http://purl.uniprot.org/uniprot/A0A239SPN0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/400065:CKV83_RS03995 ^@ http://purl.uniprot.org/uniprot/A0A239SRG9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS00675 ^@ http://purl.uniprot.org/uniprot/A0A239SLR4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/400065:CKV83_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A239SMP2 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS05680 ^@ http://purl.uniprot.org/uniprot/A0A239STC3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS04200 ^@ http://purl.uniprot.org/uniprot/A0A239SRC1 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/400065:CKV83_RS09165 ^@ http://purl.uniprot.org/uniprot/A0A239SYE4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/400065:CKV83_RS06060 ^@ http://purl.uniprot.org/uniprot/A0A239STT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS10950 ^@ http://purl.uniprot.org/uniprot/A0A239T0E3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS06395 ^@ http://purl.uniprot.org/uniprot/A0A239SUI9 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/400065:CKV83_RS03860 ^@ http://purl.uniprot.org/uniprot/A0A239SQL7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS09080 ^@ http://purl.uniprot.org/uniprot/A0A239T0F7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/400065:CKV83_RS10045 ^@ http://purl.uniprot.org/uniprot/A0A239SZ79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/400065:CKV83_RS07130 ^@ http://purl.uniprot.org/uniprot/A0A239SV05 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/400065:CKV83_RS04630 ^@ http://purl.uniprot.org/uniprot/A0A239SRQ8 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/400065:CKV83_RS08570 ^@ http://purl.uniprot.org/uniprot/A0A239SX17 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/400065:CKV83_RS10330 ^@ http://purl.uniprot.org/uniprot/A0A239SZM9 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/400065:CKV83_RS08250 ^@ http://purl.uniprot.org/uniprot/A0A239SX99 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/400065:CKV83_RS08050 ^@ http://purl.uniprot.org/uniprot/A0A239SW60 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/400065:CKV83_RS02260 ^@ http://purl.uniprot.org/uniprot/A0A239SNY1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/400065:CKV83_RS02295 ^@ http://purl.uniprot.org/uniprot/A0A239SQP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0397 family.|||Cell membrane http://togogenome.org/gene/400065:CKV83_RS08065 ^@ http://purl.uniprot.org/uniprot/A0A239SYG7 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/400065:CKV83_RS01095 ^@ http://purl.uniprot.org/uniprot/A0A239SLU8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS04225 ^@ http://purl.uniprot.org/uniprot/A0A239STJ0 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/400065:CKV83_RS09725 ^@ http://purl.uniprot.org/uniprot/A0A239SYU8 ^@ Similarity ^@ Belongs to the peptidase S1B family. http://togogenome.org/gene/400065:CKV83_RS01685 ^@ http://purl.uniprot.org/uniprot/A0A239SMR4 ^@ Subcellular Location Annotation ^@ Bacterial microcompartment http://togogenome.org/gene/400065:CKV83_RS00365 ^@ http://purl.uniprot.org/uniprot/A0A239SLE4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/400065:CKV83_RS08395 ^@ http://purl.uniprot.org/uniprot/A0A239SZ01 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/400065:CKV83_RS03965 ^@ http://purl.uniprot.org/uniprot/A0A239ST58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/400065:CKV83_RS06930 ^@ http://purl.uniprot.org/uniprot/A0A239SX44 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/400065:CKV83_RS09440 ^@ http://purl.uniprot.org/uniprot/A0A239T0J6 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS01135 ^@ http://purl.uniprot.org/uniprot/A0A239SLW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS07945 ^@ http://purl.uniprot.org/uniprot/A0A239SYA7 ^@ Similarity ^@ Belongs to the UPF0374 family. http://togogenome.org/gene/400065:CKV83_RS02280 ^@ http://purl.uniprot.org/uniprot/A0A239SNL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS01745 ^@ http://purl.uniprot.org/uniprot/A0A239SMU3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/400065:CKV83_RS07240 ^@ http://purl.uniprot.org/uniprot/A0A239SWX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS03380 ^@ http://purl.uniprot.org/uniprot/A0A239SPW0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS01200 ^@ http://purl.uniprot.org/uniprot/A0A239SMF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS04975 ^@ http://purl.uniprot.org/uniprot/A0A239SSI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-I 3-dehydroquinase family.|||Homodimer.|||Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. http://togogenome.org/gene/400065:CKV83_RS05575 ^@ http://purl.uniprot.org/uniprot/A0A239SST4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS00750 ^@ http://purl.uniprot.org/uniprot/A0A239SLG2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/400065:CKV83_RS11170 ^@ http://purl.uniprot.org/uniprot/A0A239T2T0 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS01990 ^@ http://purl.uniprot.org/uniprot/A0A239SNL9 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/400065:CKV83_RS02885 ^@ http://purl.uniprot.org/uniprot/A0A239SPS3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/400065:CKV83_RS05545 ^@ http://purl.uniprot.org/uniprot/A0A239STG7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/400065:CKV83_RS10730 ^@ http://purl.uniprot.org/uniprot/A0A239T2B2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/400065:CKV83_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A239SXR1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/400065:CKV83_RS00620 ^@ http://purl.uniprot.org/uniprot/A0A239SLT5 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/400065:CKV83_RS08725 ^@ http://purl.uniprot.org/uniprot/A0A239SX51 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/400065:CKV83_RS04550 ^@ http://purl.uniprot.org/uniprot/A0A239SSA9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/400065:CKV83_RS02735 ^@ http://purl.uniprot.org/uniprot/A0A239SRA3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/400065:CKV83_RS02245 ^@ http://purl.uniprot.org/uniprot/A0A239SNY0 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/400065:CKV83_RS00565 ^@ http://purl.uniprot.org/uniprot/A0A239SL94 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS07285 ^@ http://purl.uniprot.org/uniprot/A0A239SXB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/400065:CKV83_RS08470 ^@ http://purl.uniprot.org/uniprot/A0A239SZ36 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/400065:CKV83_RS05755 ^@ http://purl.uniprot.org/uniprot/A0A239SV58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS03890 ^@ http://purl.uniprot.org/uniprot/A0A239SQN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS04040 ^@ http://purl.uniprot.org/uniprot/A0A239ST97 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a set of proteins in which some residues (ACT_SITE, NP_BIND, REGION and BINDING) are not conserved. http://togogenome.org/gene/400065:CKV83_RS01965 ^@ http://purl.uniprot.org/uniprot/A0A239SNK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/400065:CKV83_RS05190 ^@ http://purl.uniprot.org/uniprot/A0A239SSL3 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/400065:CKV83_RS03780 ^@ http://purl.uniprot.org/uniprot/A0A239SQT8 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/400065:CKV83_RS01500 ^@ http://purl.uniprot.org/uniprot/A0A239SMU4 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/400065:CKV83_RS03655 ^@ http://purl.uniprot.org/uniprot/A0A239SQH6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS06320 ^@ http://purl.uniprot.org/uniprot/A0A239SU78 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/400065:CKV83_RS05130 ^@ http://purl.uniprot.org/uniprot/A0A239SU68 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A239SP35 ^@ Similarity ^@ Belongs to the diacylglycerol/lipid kinase family. http://togogenome.org/gene/400065:CKV83_RS01850 ^@ http://purl.uniprot.org/uniprot/A0A239SNF1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/400065:CKV83_RS08535 ^@ http://purl.uniprot.org/uniprot/A0A239SX10 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/400065:CKV83_RS05500 ^@ http://purl.uniprot.org/uniprot/A0A239SV92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/400065:CKV83_RS08095 ^@ http://purl.uniprot.org/uniprot/A0A239SYX5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/400065:CKV83_RS01535 ^@ http://purl.uniprot.org/uniprot/A0A239SPG6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/400065:CKV83_RS07950 ^@ http://purl.uniprot.org/uniprot/A0A239SWJ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/400065:CKV83_RS04635 ^@ http://purl.uniprot.org/uniprot/A0A239SU32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell membrane|||Component of the transport system for branched-chain amino acids.|||Membrane http://togogenome.org/gene/400065:CKV83_RS10905 ^@ http://purl.uniprot.org/uniprot/A0A239T080 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/400065:CKV83_RS06350 ^@ http://purl.uniprot.org/uniprot/A0A239SVP9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CobB/CobQ family. GatD subfamily.|||Forms a heterodimer with MurT.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT. http://togogenome.org/gene/400065:CKV83_RS09170 ^@ http://purl.uniprot.org/uniprot/A0A239SYP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS10265 ^@ http://purl.uniprot.org/uniprot/A0A239T1S2 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/400065:CKV83_RS10555 ^@ http://purl.uniprot.org/uniprot/A0A239T0A8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS01740 ^@ http://purl.uniprot.org/uniprot/A0A239SMR7 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/400065:CKV83_RS04095 ^@ http://purl.uniprot.org/uniprot/A0A239SRN0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/400065:CKV83_RS08960 ^@ http://purl.uniprot.org/uniprot/A0A239SXS2 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS04120 ^@ http://purl.uniprot.org/uniprot/A0A239SSV3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/400065:CKV83_RS08575 ^@ http://purl.uniprot.org/uniprot/A0A239SZ97 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/400065:CKV83_RS00550 ^@ http://purl.uniprot.org/uniprot/A0A239SLL7 ^@ Similarity ^@ Belongs to the aldolase LacD family. http://togogenome.org/gene/400065:CKV83_RS06245 ^@ http://purl.uniprot.org/uniprot/A0A239STX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0154 family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A239SZG2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS01465 ^@ http://purl.uniprot.org/uniprot/A0A239SPM2 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/400065:CKV83_RS00610 ^@ http://purl.uniprot.org/uniprot/A0A239SL85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS07650 ^@ http://purl.uniprot.org/uniprot/A0A239SW98 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/400065:CKV83_RS00300 ^@ http://purl.uniprot.org/uniprot/A0A239SKY1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS01960 ^@ http://purl.uniprot.org/uniprot/A0A239SN63 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/400065:CKV83_RS04075 ^@ http://purl.uniprot.org/uniprot/A0A239STB8 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/400065:CKV83_RS09830 ^@ http://purl.uniprot.org/uniprot/A0A239T1L4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS07390 ^@ http://purl.uniprot.org/uniprot/A0A239SW14 ^@ Similarity ^@ Belongs to the ThiD family. http://togogenome.org/gene/400065:CKV83_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A239SPI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane|||Part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/400065:CKV83_RS06430 ^@ http://purl.uniprot.org/uniprot/A0A239SW27 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS08055 ^@ http://purl.uniprot.org/uniprot/A0A239SY42 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/400065:CKV83_RS00030 ^@ http://purl.uniprot.org/uniprot/A0A239SMM8 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/400065:CKV83_RS03675 ^@ http://purl.uniprot.org/uniprot/A0A239SS67 ^@ Function|||Similarity ^@ Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.|||Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. http://togogenome.org/gene/400065:CKV83_RS00560 ^@ http://purl.uniprot.org/uniprot/A0A239SND5 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/400065:CKV83_RS03945 ^@ http://purl.uniprot.org/uniprot/A0A239SRE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS07785 ^@ http://purl.uniprot.org/uniprot/A0A239SWI2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS06645 ^@ http://purl.uniprot.org/uniprot/A0A239SWU1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/400065:CKV83_RS00705 ^@ http://purl.uniprot.org/uniprot/A0A239SLS0 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/400065:CKV83_RS00205 ^@ http://purl.uniprot.org/uniprot/A0A239SKT9 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/400065:CKV83_RS11100 ^@ http://purl.uniprot.org/uniprot/A0A239T0V3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS02080 ^@ http://purl.uniprot.org/uniprot/A0A239SN61 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS00040 ^@ http://purl.uniprot.org/uniprot/A0A239SM66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS10190 ^@ http://purl.uniprot.org/uniprot/A0A239SZC7 ^@ Similarity ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/400065:CKV83_RS02970 ^@ http://purl.uniprot.org/uniprot/A0A239SPG7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS03105 ^@ http://purl.uniprot.org/uniprot/A0A239SPM5 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/400065:CKV83_RS06255 ^@ http://purl.uniprot.org/uniprot/A0A239SWA1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/400065:CKV83_RS07980 ^@ http://purl.uniprot.org/uniprot/A0A239SW24 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/400065:CKV83_RS07880 ^@ http://purl.uniprot.org/uniprot/A0A239SWD2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/400065:CKV83_RS10055 ^@ http://purl.uniprot.org/uniprot/A0A239T006 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/400065:CKV83_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A239SPJ8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/400065:CKV83_RS04915 ^@ http://purl.uniprot.org/uniprot/A0A239SSN4 ^@ Function|||Similarity ^@ Belongs to the CpsD/CapB family.|||Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide. http://togogenome.org/gene/400065:CKV83_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A239SY07 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/400065:CKV83_RS00835 ^@ http://purl.uniprot.org/uniprot/A0A239SM25 ^@ Similarity ^@ Belongs to the DCK/DGK family. http://togogenome.org/gene/400065:CKV83_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A239SWL7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/400065:CKV83_RS06870 ^@ http://purl.uniprot.org/uniprot/A0A239SV43 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/400065:CKV83_RS04005 ^@ http://purl.uniprot.org/uniprot/A0A239SSY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS08355 ^@ http://purl.uniprot.org/uniprot/A0A239SWP7 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS08180 ^@ http://purl.uniprot.org/uniprot/A0A239SWV9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS08935 ^@ http://purl.uniprot.org/uniprot/A0A239SZU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS09575 ^@ http://purl.uniprot.org/uniprot/A0A239T0B9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/400065:CKV83_RS00575 ^@ http://purl.uniprot.org/uniprot/A0A239SL75 ^@ Activity Regulation|||Function|||PTM|||Similarity|||Subunit ^@ Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme. http://togogenome.org/gene/400065:CKV83_RS03820 ^@ http://purl.uniprot.org/uniprot/A0A239SR79 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A239SVV8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS00165 ^@ http://purl.uniprot.org/uniprot/A0A239SKP8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/400065:CKV83_RS03685 ^@ http://purl.uniprot.org/uniprot/A0A239SSR2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/400065:CKV83_RS00380 ^@ http://purl.uniprot.org/uniprot/A0A239SL17 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/400065:CKV83_RS09900 ^@ http://purl.uniprot.org/uniprot/A0A239SZA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS00045 ^@ http://purl.uniprot.org/uniprot/A0A239SKM3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family. RnhC subfamily.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/400065:CKV83_RS02535 ^@ http://purl.uniprot.org/uniprot/A0A239SP90 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/400065:CKV83_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A239SQ41 ^@ Similarity ^@ Belongs to the diacylglycerol/lipid kinase family. http://togogenome.org/gene/400065:CKV83_RS09935 ^@ http://purl.uniprot.org/uniprot/A0A239T101 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 36 family. http://togogenome.org/gene/400065:CKV83_RS11750 ^@ http://purl.uniprot.org/uniprot/A0A239T0C7 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/400065:CKV83_RS08915 ^@ http://purl.uniprot.org/uniprot/A0A239SXF8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/400065:CKV83_RS02360 ^@ http://purl.uniprot.org/uniprot/A0A239SP21 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A239SPG5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiM family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Membrane|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/400065:CKV83_RS06495 ^@ http://purl.uniprot.org/uniprot/A0A239SUR5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/400065:CKV83_RS02665 ^@ http://purl.uniprot.org/uniprot/A0A239SNY2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/400065:CKV83_RS05870 ^@ http://purl.uniprot.org/uniprot/A0A239ST55 ^@ Function|||Similarity ^@ Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.|||Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS01875 ^@ http://purl.uniprot.org/uniprot/A0A239SNG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/400065:CKV83_RS05835 ^@ http://purl.uniprot.org/uniprot/A0A239STC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS11115 ^@ http://purl.uniprot.org/uniprot/A0A239T167 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/400065:CKV83_RS09415 ^@ http://purl.uniprot.org/uniprot/A0A239SYA6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS04355 ^@ http://purl.uniprot.org/uniprot/A0A239SRI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/400065:CKV83_RS02990 ^@ http://purl.uniprot.org/uniprot/A0A239SPI4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/400065:CKV83_RS00075 ^@ http://purl.uniprot.org/uniprot/A0A239SKM8 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/400065:CKV83_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A239SSM1 ^@ Caution|||Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Belongs to the MsrB Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.|||In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.|||In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS01705 ^@ http://purl.uniprot.org/uniprot/A0A239SMS4 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/400065:CKV83_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A239SMF1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Cell membrane|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/400065:CKV83_RS08560 ^@ http://purl.uniprot.org/uniprot/A0A239SWW2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/400065:CKV83_RS01020 ^@ http://purl.uniprot.org/uniprot/A0A239SLR6 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/400065:CKV83_RS05455 ^@ http://purl.uniprot.org/uniprot/A0A239SSN2 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/400065:CKV83_RS01230 ^@ http://purl.uniprot.org/uniprot/A0A239SP18 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/400065:CKV83_RS09720 ^@ http://purl.uniprot.org/uniprot/A0A239T0L5 ^@ Similarity ^@ Belongs to the UPF0177 family. http://togogenome.org/gene/400065:CKV83_RS04160 ^@ http://purl.uniprot.org/uniprot/A0A239SRQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-ACP thioesterase family.|||Belongs to the thioester dehydratase family. FabZ subfamily.|||chloroplast http://togogenome.org/gene/400065:CKV83_RS05150 ^@ http://purl.uniprot.org/uniprot/A0A239SSI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS04610 ^@ http://purl.uniprot.org/uniprot/A0A239SU23 ^@ Caution|||Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS10445 ^@ http://purl.uniprot.org/uniprot/A0A239T203 ^@ Function|||Similarity|||Subunit ^@ A non-essential component of RNA polymerase (RNAP).|||Belongs to the RNA polymerase subunit epsilon family.|||RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/400065:CKV83_RS10615 ^@ http://purl.uniprot.org/uniprot/A0A239T1S3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS08705 ^@ http://purl.uniprot.org/uniprot/A0A239SZU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS05715 ^@ http://purl.uniprot.org/uniprot/A0A239STL9 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/400065:CKV83_RS07615 ^@ http://purl.uniprot.org/uniprot/A0A239SXE9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/400065:CKV83_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A239SQS9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS03155 ^@ http://purl.uniprot.org/uniprot/A0A239SPJ4 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/400065:CKV83_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A239SN76 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/400065:CKV83_RS01645 ^@ http://purl.uniprot.org/uniprot/A0A239SMN3 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/400065:CKV83_RS01835 ^@ http://purl.uniprot.org/uniprot/A0A239SMW9 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/400065:CKV83_RS00145 ^@ http://purl.uniprot.org/uniprot/A0A239SL91 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/400065:CKV83_RS07830 ^@ http://purl.uniprot.org/uniprot/A0A239SXR7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/400065:CKV83_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A239SLJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 32 family.|||Cytoplasm|||Enables the bacterium to metabolize sucrose as a sole carbon source. http://togogenome.org/gene/400065:CKV83_RS10545 ^@ http://purl.uniprot.org/uniprot/A0A239SZV0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/400065:CKV83_RS06695 ^@ http://purl.uniprot.org/uniprot/A0A239SWH0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/400065:CKV83_RS01495 ^@ http://purl.uniprot.org/uniprot/A0A239SMI8 ^@ Similarity ^@ Belongs to the CvfB family. http://togogenome.org/gene/400065:CKV83_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A239ST46 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/400065:CKV83_RS06400 ^@ http://purl.uniprot.org/uniprot/A0A239STW2 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/400065:CKV83_RS10250 ^@ http://purl.uniprot.org/uniprot/A0A239T1B7 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/400065:CKV83_RS02875 ^@ http://purl.uniprot.org/uniprot/A0A239SP68 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/400065:CKV83_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A239SWN4 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/400065:CKV83_RS08505 ^@ http://purl.uniprot.org/uniprot/A0A239SZI4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/400065:CKV83_RS03315 ^@ http://purl.uniprot.org/uniprot/A0A239SS51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS06260 ^@ http://purl.uniprot.org/uniprot/A0A239SVV4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/400065:CKV83_RS00265 ^@ http://purl.uniprot.org/uniprot/A0A239SMQ4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/400065:CKV83_RS03455 ^@ http://purl.uniprot.org/uniprot/A0A239SRT9 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/400065:CKV83_RS10165 ^@ http://purl.uniprot.org/uniprot/A0A239SZW5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/400065:CKV83_RS04270 ^@ http://purl.uniprot.org/uniprot/A0A239ST28 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/400065:CKV83_RS04970 ^@ http://purl.uniprot.org/uniprot/A0A239SU96 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS04710 ^@ http://purl.uniprot.org/uniprot/A0A239STM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/400065:CKV83_RS09410 ^@ http://purl.uniprot.org/uniprot/A0A239SYD6 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/400065:CKV83_RS06705 ^@ http://purl.uniprot.org/uniprot/A0A239SUH4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS10310 ^@ http://purl.uniprot.org/uniprot/A0A239SZK9 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/400065:CKV83_RS04805 ^@ http://purl.uniprot.org/uniprot/A0A239SSI8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/400065:CKV83_RS05650 ^@ http://purl.uniprot.org/uniprot/A0A239SV15 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/400065:CKV83_RS10065 ^@ http://purl.uniprot.org/uniprot/A0A239T1V7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS00335 ^@ http://purl.uniprot.org/uniprot/A0A239SMT5 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/400065:CKV83_RS01360 ^@ http://purl.uniprot.org/uniprot/A0A239SMN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS06535 ^@ http://purl.uniprot.org/uniprot/A0A239SWN2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/400065:CKV83_RS07120 ^@ http://purl.uniprot.org/uniprot/A0A239SVL5 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/400065:CKV83_RS10230 ^@ http://purl.uniprot.org/uniprot/A0A239SZJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ribonuclease M5 family.|||Cytoplasm|||Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. http://togogenome.org/gene/400065:CKV83_RS03460 ^@ http://purl.uniprot.org/uniprot/A0A239SQ75 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS08845 ^@ http://purl.uniprot.org/uniprot/A0A239T022 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS08850 ^@ http://purl.uniprot.org/uniprot/A0A239SXY2 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/400065:CKV83_RS08245 ^@ http://purl.uniprot.org/uniprot/A0A239SX86 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/400065:CKV83_RS00170 ^@ http://purl.uniprot.org/uniprot/A0A239SLA0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS06105 ^@ http://purl.uniprot.org/uniprot/A0A239STV6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the YabA family.|||Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.|||Involved in initiation control of chromosome replication. http://togogenome.org/gene/400065:CKV83_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A239SXE0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/400065:CKV83_RS02645 ^@ http://purl.uniprot.org/uniprot/A0A239SP39 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS06290 ^@ http://purl.uniprot.org/uniprot/A0A239STX7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/400065:CKV83_RS09125 ^@ http://purl.uniprot.org/uniprot/A0A239SYK7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.|||Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).|||Membrane http://togogenome.org/gene/400065:CKV83_RS06230 ^@ http://purl.uniprot.org/uniprot/A0A239SUB7 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/400065:CKV83_RS08380 ^@ http://purl.uniprot.org/uniprot/A0A239SWM4 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/400065:CKV83_RS05285 ^@ http://purl.uniprot.org/uniprot/A0A239ST70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS05320 ^@ http://purl.uniprot.org/uniprot/A0A239SSY4 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/400065:CKV83_RS01065 ^@ http://purl.uniprot.org/uniprot/A0A239SM85 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/400065:CKV83_RS05975 ^@ http://purl.uniprot.org/uniprot/A0A239STH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS03645 ^@ http://purl.uniprot.org/uniprot/A0A239SSF5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/400065:CKV83_RS00070 ^@ http://purl.uniprot.org/uniprot/A0A239SMG7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/400065:CKV83_RS05240 ^@ http://purl.uniprot.org/uniprot/A0A239SSN9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/400065:CKV83_RS00285 ^@ http://purl.uniprot.org/uniprot/A0A239SMR5 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/400065:CKV83_RS05790 ^@ http://purl.uniprot.org/uniprot/A0A239SV81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS09905 ^@ http://purl.uniprot.org/uniprot/A0A239SZ61 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/400065:CKV83_RS10715 ^@ http://purl.uniprot.org/uniprot/A0A239T1V3 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/400065:CKV83_RS02960 ^@ http://purl.uniprot.org/uniprot/A0A239SPV3 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/400065:CKV83_RS09065 ^@ http://purl.uniprot.org/uniprot/A0A239SY92 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/400065:CKV83_RS08810 ^@ http://purl.uniprot.org/uniprot/A0A239SY46 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/400065:CKV83_RS02905 ^@ http://purl.uniprot.org/uniprot/A0A239SPT2 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/400065:CKV83_RS10415 ^@ http://purl.uniprot.org/uniprot/A0A239T285 ^@ Function|||Similarity ^@ Belongs to the PduL family.|||Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. http://togogenome.org/gene/400065:CKV83_RS00130 ^@ http://purl.uniprot.org/uniprot/A0A239SKM5 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS07085 ^@ http://purl.uniprot.org/uniprot/A0A239SUT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS05605 ^@ http://purl.uniprot.org/uniprot/A0A239ST29 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit.|||Cleaves the N-terminal amino acid of tripeptides.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS03200 ^@ http://purl.uniprot.org/uniprot/A0A239SQ70 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS02955 ^@ http://purl.uniprot.org/uniprot/A0A239SPG1 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/400065:CKV83_RS08925 ^@ http://purl.uniprot.org/uniprot/A0A239SZB6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily. http://togogenome.org/gene/400065:CKV83_RS04510 ^@ http://purl.uniprot.org/uniprot/A0A239SRY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0298 family.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS09550 ^@ http://purl.uniprot.org/uniprot/A0A239SZ66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS10920 ^@ http://purl.uniprot.org/uniprot/A0A239T0D5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS08240 ^@ http://purl.uniprot.org/uniprot/A0A239SWY2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.|||Cell membrane|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. http://togogenome.org/gene/400065:CKV83_RS01680 ^@ http://purl.uniprot.org/uniprot/A0A239SPA5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutC family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/400065:CKV83_RS01270 ^@ http://purl.uniprot.org/uniprot/A0A239SPC7 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/400065:CKV83_RS02780 ^@ http://purl.uniprot.org/uniprot/A0A239SP98 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS06820 ^@ http://purl.uniprot.org/uniprot/A0A239SUW0 ^@ Cofactor|||Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Binds 1 FAD per subunit.|||Binds 1 FMN covalently per subunit. http://togogenome.org/gene/400065:CKV83_RS01795 ^@ http://purl.uniprot.org/uniprot/A0A239SMU1 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/400065:CKV83_RS02910 ^@ http://purl.uniprot.org/uniprot/A0A239SPT3 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/400065:CKV83_RS09700 ^@ http://purl.uniprot.org/uniprot/A0A239SYX0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS10645 ^@ http://purl.uniprot.org/uniprot/A0A239T002 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS08490 ^@ http://purl.uniprot.org/uniprot/A0A239SXC7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/400065:CKV83_RS08520 ^@ http://purl.uniprot.org/uniprot/A0A239SXP1 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/400065:CKV83_RS08720 ^@ http://purl.uniprot.org/uniprot/A0A239SXZ4 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/400065:CKV83_RS10135 ^@ http://purl.uniprot.org/uniprot/A0A239SZJ0 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/400065:CKV83_RS03700 ^@ http://purl.uniprot.org/uniprot/A0A239SSS2 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/400065:CKV83_RS03495 ^@ http://purl.uniprot.org/uniprot/A0A239SQQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS03520 ^@ http://purl.uniprot.org/uniprot/A0A239SSH6 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/400065:CKV83_RS06370 ^@ http://purl.uniprot.org/uniprot/A0A239STS8 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/400065:CKV83_RS04450 ^@ http://purl.uniprot.org/uniprot/A0A239SRI9 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/400065:CKV83_RS03770 ^@ http://purl.uniprot.org/uniprot/A0A239SQH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS09920 ^@ http://purl.uniprot.org/uniprot/A0A239SZV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS06500 ^@ http://purl.uniprot.org/uniprot/A0A239STZ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/400065:CKV83_RS08585 ^@ http://purl.uniprot.org/uniprot/A0A239SXS5 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/400065:CKV83_RS08500 ^@ http://purl.uniprot.org/uniprot/A0A239SWX5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/400065:CKV83_RS06205 ^@ http://purl.uniprot.org/uniprot/A0A239STT4 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/400065:CKV83_RS00665 ^@ http://purl.uniprot.org/uniprot/A0A239SN87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A239SMF5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/400065:CKV83_RS11000 ^@ http://purl.uniprot.org/uniprot/A0A239T262 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS00490 ^@ http://purl.uniprot.org/uniprot/A0A239SN10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS05340 ^@ http://purl.uniprot.org/uniprot/A0A239SSJ2 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/400065:CKV83_RS04595 ^@ http://purl.uniprot.org/uniprot/A0A239STI2 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/400065:CKV83_RS04910 ^@ http://purl.uniprot.org/uniprot/A0A239SSA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS06015 ^@ http://purl.uniprot.org/uniprot/A0A239STA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PrsA family.|||Cell membrane|||Membrane|||Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. http://togogenome.org/gene/400065:CKV83_RS10995 ^@ http://purl.uniprot.org/uniprot/A0A239T0R5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/400065:CKV83_RS05050 ^@ http://purl.uniprot.org/uniprot/A0A239SS76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS04430 ^@ http://purl.uniprot.org/uniprot/A0A239STU8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS09755 ^@ http://purl.uniprot.org/uniprot/A0A239SZL0 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/400065:CKV83_RS06505 ^@ http://purl.uniprot.org/uniprot/A0A239SU98 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/400065:CKV83_RS06900 ^@ http://purl.uniprot.org/uniprot/A0A239SUR8 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS07940 ^@ http://purl.uniprot.org/uniprot/A0A239SW26 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS03480 ^@ http://purl.uniprot.org/uniprot/A0A239SQ18 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/400065:CKV83_RS05550 ^@ http://purl.uniprot.org/uniprot/A0A239SUX7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/400065:CKV83_RS10085 ^@ http://purl.uniprot.org/uniprot/A0A239SZ98 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/400065:CKV83_RS03335 ^@ http://purl.uniprot.org/uniprot/A0A239SRZ1 ^@ Function|||Similarity ^@ Belongs to the peptidase S8 family.|||This virulence factor of S.pyogenes specifically cleaves the human serum chemotaxin C5a at '68-Lys-|-Asp-69' bond near its C-terminus, destroying its ability to serve as a chemoattractant. http://togogenome.org/gene/400065:CKV83_RS01575 ^@ http://purl.uniprot.org/uniprot/A0A239SPI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS03760 ^@ http://purl.uniprot.org/uniprot/A0A239SQI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS05775 ^@ http://purl.uniprot.org/uniprot/A0A239ST08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS04020 ^@ http://purl.uniprot.org/uniprot/A0A239ST85 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/400065:CKV83_RS07420 ^@ http://purl.uniprot.org/uniprot/A0A239SW00 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS00005 ^@ http://purl.uniprot.org/uniprot/A0A239SKG8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/400065:CKV83_RS02105 ^@ http://purl.uniprot.org/uniprot/A0A239SN80 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/400065:CKV83_RS06610 ^@ http://purl.uniprot.org/uniprot/A0A239SUG3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS10625 ^@ http://purl.uniprot.org/uniprot/A0A239T0N6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. http://togogenome.org/gene/400065:CKV83_RS03950 ^@ http://purl.uniprot.org/uniprot/A0A239SQS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS01865 ^@ http://purl.uniprot.org/uniprot/A0A239SPK0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/400065:CKV83_RS01820 ^@ http://purl.uniprot.org/uniprot/A0A239SQ47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS10355 ^@ http://purl.uniprot.org/uniprot/A0A239SZM8 ^@ Function|||PTM|||Similarity ^@ Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.|||Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.|||Requires the activating protein CutD to generate the key active site glycyl radical on Gly-823 that is involved in catalysis. http://togogenome.org/gene/400065:CKV83_RS04750 ^@ http://purl.uniprot.org/uniprot/A0A239SS27 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/400065:CKV83_RS10770 ^@ http://purl.uniprot.org/uniprot/A0A239T055 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS04180 ^@ http://purl.uniprot.org/uniprot/A0A239SRB2 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/400065:CKV83_RS01320 ^@ http://purl.uniprot.org/uniprot/A0A239SMS0 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/400065:CKV83_RS10220 ^@ http://purl.uniprot.org/uniprot/A0A239SZY8 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/400065:CKV83_RS10385 ^@ http://purl.uniprot.org/uniprot/A0A239T275 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/400065:CKV83_RS00625 ^@ http://purl.uniprot.org/uniprot/A0A239SNF7 ^@ Function ^@ Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions. http://togogenome.org/gene/400065:CKV83_RS10570 ^@ http://purl.uniprot.org/uniprot/A0A239T0L7 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/400065:CKV83_RS00090 ^@ http://purl.uniprot.org/uniprot/A0A239SMI0 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/400065:CKV83_RS08030 ^@ http://purl.uniprot.org/uniprot/A0A239SYF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/400065:CKV83_RS02300 ^@ http://purl.uniprot.org/uniprot/A0A239SNF9 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/400065:CKV83_RS00975 ^@ http://purl.uniprot.org/uniprot/A0A239SM92 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/400065:CKV83_RS01490 ^@ http://purl.uniprot.org/uniprot/A0A239SPF1 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS09255 ^@ http://purl.uniprot.org/uniprot/A0A239T0P8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/400065:CKV83_RS04960 ^@ http://purl.uniprot.org/uniprot/A0A239SS94 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/400065:CKV83_RS07370 ^@ http://purl.uniprot.org/uniprot/A0A239SVB0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/400065:CKV83_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A239SM55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS09595 ^@ http://purl.uniprot.org/uniprot/A0A239T0D1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/400065:CKV83_RS03990 ^@ http://purl.uniprot.org/uniprot/A0A239SR10 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/400065:CKV83_RS07750 ^@ http://purl.uniprot.org/uniprot/A0A239SVS3 ^@ Function|||Similarity ^@ Belongs to the NanE family.|||Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). http://togogenome.org/gene/400065:CKV83_RS08285 ^@ http://purl.uniprot.org/uniprot/A0A239SZ63 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecU family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation. http://togogenome.org/gene/400065:CKV83_RS02515 ^@ http://purl.uniprot.org/uniprot/A0A239SNP3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/400065:CKV83_RS05075 ^@ http://purl.uniprot.org/uniprot/A0A239SSM6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. http://togogenome.org/gene/400065:CKV83_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A239SLM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CodY family.|||Cytoplasm|||DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion. http://togogenome.org/gene/400065:CKV83_RS03470 ^@ http://purl.uniprot.org/uniprot/A0A239SQ28 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/400065:CKV83_RS00220 ^@ http://purl.uniprot.org/uniprot/A0A239SLC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/400065:CKV83_RS00235 ^@ http://purl.uniprot.org/uniprot/A0A239SKS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/400065:CKV83_RS03485 ^@ http://purl.uniprot.org/uniprot/A0A239SS73 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/400065:CKV83_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A239SV56 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/400065:CKV83_RS05495 ^@ http://purl.uniprot.org/uniprot/A0A239SSQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/400065:CKV83_RS04100 ^@ http://purl.uniprot.org/uniprot/A0A239SR07 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by fructose 1,6-bisphosphate (FBP).|||Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/400065:CKV83_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A239SNM1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/400065:CKV83_RS03125 ^@ http://purl.uniprot.org/uniprot/A0A239SPI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/400065:CKV83_RS10345 ^@ http://purl.uniprot.org/uniprot/A0A239T034 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/400065:CKV83_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A239SVU6 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/400065:CKV83_RS01860 ^@ http://purl.uniprot.org/uniprot/A0A239SN22 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/400065:CKV83_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A239SZH1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/400065:CKV83_RS01815 ^@ http://purl.uniprot.org/uniprot/A0A239SMW4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiN family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/400065:CKV83_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A239SQR3 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/400065:CKV83_RS08890 ^@ http://purl.uniprot.org/uniprot/A0A239SXK5 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/400065:CKV83_RS08020 ^@ http://purl.uniprot.org/uniprot/A0A239SWW6 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/400065:CKV83_RS00230 ^@ http://purl.uniprot.org/uniprot/A0A239SME8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsQ/DivIB family. DivIB subfamily.|||Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.|||Cell membrane http://togogenome.org/gene/400065:CKV83_RS08970 ^@ http://purl.uniprot.org/uniprot/A0A239T097 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/400065:CKV83_RS09910 ^@ http://purl.uniprot.org/uniprot/A0A239T1R2 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/400065:CKV83_RS09705 ^@ http://purl.uniprot.org/uniprot/A0A239SYT6 ^@ Subcellular Location Annotation ^@ Membrane