http://togogenome.org/gene/401053:ACIPR4_RS16010 ^@ http://purl.uniprot.org/uniprot/E8V7K0 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/401053:ACIPR4_RS15105 ^@ http://purl.uniprot.org/uniprot/E8V5Y0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/401053:ACIPR4_RS20160 ^@ http://purl.uniprot.org/uniprot/E8V4G3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS12660 ^@ http://purl.uniprot.org/uniprot/E8V0A4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS05060 ^@ http://purl.uniprot.org/uniprot/E8V8E3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/401053:ACIPR4_RS14180 ^@ http://purl.uniprot.org/uniprot/E8V3K6 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS06965 ^@ http://purl.uniprot.org/uniprot/E8V0S6 ^@ Function|||Subcellular Location Annotation ^@ Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.|||Cell inner membrane http://togogenome.org/gene/401053:ACIPR4_RS06205 ^@ http://purl.uniprot.org/uniprot/E8UYH9 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS07150 ^@ http://purl.uniprot.org/uniprot/E8V0W5 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/401053:ACIPR4_RS02135 ^@ http://purl.uniprot.org/uniprot/E8V2D4 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/401053:ACIPR4_RS05860 ^@ http://purl.uniprot.org/uniprot/E8UYB6 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/401053:ACIPR4_RS19230 ^@ http://purl.uniprot.org/uniprot/E8V250 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/401053:ACIPR4_RS12890 ^@ http://purl.uniprot.org/uniprot/E8V119 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS10605 ^@ http://purl.uniprot.org/uniprot/E8V8F2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS19505 ^@ http://purl.uniprot.org/uniprot/E8V2W3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS17320 ^@ http://purl.uniprot.org/uniprot/E8UXZ9 ^@ Function|||Similarity ^@ Belongs to the uricase family.|||Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. http://togogenome.org/gene/401053:ACIPR4_RS15460 ^@ http://purl.uniprot.org/uniprot/E8V6R8 ^@ Similarity ^@ Belongs to the aldolase LacD family. http://togogenome.org/gene/401053:ACIPR4_RS04540 ^@ http://purl.uniprot.org/uniprot/E8V7P4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS06295 ^@ http://purl.uniprot.org/uniprot/E8UZ67 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/401053:ACIPR4_RS17500 ^@ http://purl.uniprot.org/uniprot/E8UY33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS09575 ^@ http://purl.uniprot.org/uniprot/E8V6I8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS17715 ^@ http://purl.uniprot.org/uniprot/E8UYU3 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily. http://togogenome.org/gene/401053:ACIPR4_RS20375 ^@ http://purl.uniprot.org/uniprot/E8V4K7 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/401053:ACIPR4_RS14240 ^@ http://purl.uniprot.org/uniprot/E8V481 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS07290 ^@ http://purl.uniprot.org/uniprot/E8V0Z1 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 Fe cation per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/401053:ACIPR4_RS09785 ^@ http://purl.uniprot.org/uniprot/E8V6M9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS07945 ^@ http://purl.uniprot.org/uniprot/E8V2J4 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/401053:ACIPR4_RS19955 ^@ http://purl.uniprot.org/uniprot/E8V3R0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS08745 ^@ http://purl.uniprot.org/uniprot/E8V475 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/401053:ACIPR4_RS06650 ^@ http://purl.uniprot.org/uniprot/E8UZZ9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 30 family. http://togogenome.org/gene/401053:ACIPR4_RS00040 ^@ http://purl.uniprot.org/uniprot/E8UY39 ^@ Similarity ^@ Belongs to the ALAD family. http://togogenome.org/gene/401053:ACIPR4_RS19750 ^@ http://purl.uniprot.org/uniprot/E8V3L9 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/401053:ACIPR4_RS16230 ^@ http://purl.uniprot.org/uniprot/E8V839 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/401053:ACIPR4_RS05300 ^@ http://purl.uniprot.org/uniprot/E8UX06 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS05070 ^@ http://purl.uniprot.org/uniprot/E8V8E5 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/401053:ACIPR4_RS10985 ^@ http://purl.uniprot.org/uniprot/E8UX44 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS06925 ^@ http://purl.uniprot.org/uniprot/E8V054 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/401053:ACIPR4_RS04345 ^@ http://purl.uniprot.org/uniprot/E8V763 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS21240 ^@ http://purl.uniprot.org/uniprot/E8V6Y3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS09655 ^@ http://purl.uniprot.org/uniprot/E8V6K4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS10285 ^@ http://purl.uniprot.org/uniprot/E8V7U4 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS18835 ^@ http://purl.uniprot.org/uniprot/E8V1B4 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/401053:ACIPR4_RS04440 ^@ http://purl.uniprot.org/uniprot/E8V7M4 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/401053:ACIPR4_RS10930 ^@ http://purl.uniprot.org/uniprot/E8V8L7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/401053:ACIPR4_RS06395 ^@ http://purl.uniprot.org/uniprot/E8UZ84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS06385 ^@ http://purl.uniprot.org/uniprot/E8UZ82 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/401053:ACIPR4_RS01380 ^@ http://purl.uniprot.org/uniprot/E8V0Q9 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/401053:ACIPR4_RS13085 ^@ http://purl.uniprot.org/uniprot/E8V159 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS20230 ^@ http://purl.uniprot.org/uniprot/E8V4H8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/401053:ACIPR4_RS15625 ^@ http://purl.uniprot.org/uniprot/E8V6V2 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/401053:ACIPR4_RS10815 ^@ http://purl.uniprot.org/uniprot/E8V8J4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/401053:ACIPR4_RS04110 ^@ http://purl.uniprot.org/uniprot/E8V714 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS16015 ^@ http://purl.uniprot.org/uniprot/E8V7K1 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/401053:ACIPR4_RS17625 ^@ http://purl.uniprot.org/uniprot/E8UYS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS10345 ^@ http://purl.uniprot.org/uniprot/E8V7V6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/401053:ACIPR4_RS06835 ^@ http://purl.uniprot.org/uniprot/E8V035 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS15870 ^@ http://purl.uniprot.org/uniprot/E8V7H3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/401053:ACIPR4_RS04375 ^@ http://purl.uniprot.org/uniprot/E8V769 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell inner membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS05775 ^@ http://purl.uniprot.org/uniprot/E8UXP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/401053:ACIPR4_RS12380 ^@ http://purl.uniprot.org/uniprot/E8UZI9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS04385 ^@ http://purl.uniprot.org/uniprot/E8V7L3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/401053:ACIPR4_RS07680 ^@ http://purl.uniprot.org/uniprot/E8V1T0 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS08295 ^@ http://purl.uniprot.org/uniprot/E8V3B9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/401053:ACIPR4_RS08325 ^@ http://purl.uniprot.org/uniprot/E8V3C5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS06050 ^@ http://purl.uniprot.org/uniprot/E8UYE8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS06950 ^@ http://purl.uniprot.org/uniprot/E8V059 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.|||Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.|||Homodimer.|||In the C-terminal section; belongs to the cytidylyltransferase family.|||In the N-terminal section; belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/401053:ACIPR4_RS15965 ^@ http://purl.uniprot.org/uniprot/E8V7J1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/401053:ACIPR4_RS17165 ^@ http://purl.uniprot.org/uniprot/E8UXW9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/401053:ACIPR4_RS18035 ^@ http://purl.uniprot.org/uniprot/E8UZN1 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS11240 ^@ http://purl.uniprot.org/uniprot/E8UX95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GRP transporter (TC 2.A.7.5) family.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS05225 ^@ http://purl.uniprot.org/uniprot/E8UWZ1 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/401053:ACIPR4_RS02400 ^@ http://purl.uniprot.org/uniprot/E8V344 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS13405 ^@ http://purl.uniprot.org/uniprot/E8V1Y2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS17855 ^@ http://purl.uniprot.org/uniprot/E8UYX2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/401053:ACIPR4_RS12695 ^@ http://purl.uniprot.org/uniprot/E8V0B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS10150 ^@ http://purl.uniprot.org/uniprot/E8V7C8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS16460 ^@ http://purl.uniprot.org/uniprot/E8V8M7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS10705 ^@ http://purl.uniprot.org/uniprot/E8V8H2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/401053:ACIPR4_RS01080 ^@ http://purl.uniprot.org/uniprot/E8UZY3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS00060 ^@ http://purl.uniprot.org/uniprot/E8UY43 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/401053:ACIPR4_RS07215 ^@ http://purl.uniprot.org/uniprot/E8V0X8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS18095 ^@ http://purl.uniprot.org/uniprot/E8UZP3 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS14355 ^@ http://purl.uniprot.org/uniprot/E8V4A2 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/401053:ACIPR4_RS20490 ^@ http://purl.uniprot.org/uniprot/E8V595 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/401053:ACIPR4_RS05520 ^@ http://purl.uniprot.org/uniprot/E8UXJ1 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/401053:ACIPR4_RS15110 ^@ http://purl.uniprot.org/uniprot/E8V5Y1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS14155 ^@ http://purl.uniprot.org/uniprot/E8V3K1 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS10970 ^@ http://purl.uniprot.org/uniprot/E8UX41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS04550 ^@ http://purl.uniprot.org/uniprot/E8V7P6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/401053:ACIPR4_RS19385 ^@ http://purl.uniprot.org/uniprot/E8V2T9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/401053:ACIPR4_RS07100 ^@ http://purl.uniprot.org/uniprot/E8V0V5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS06160 ^@ http://purl.uniprot.org/uniprot/E8UYH0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 4 family. http://togogenome.org/gene/401053:ACIPR4_RS13095 ^@ http://purl.uniprot.org/uniprot/E8V161 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS14820 ^@ http://purl.uniprot.org/uniprot/E8V553 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/401053:ACIPR4_RS01905 ^@ http://purl.uniprot.org/uniprot/E8V288 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/401053:ACIPR4_RS17455 ^@ http://purl.uniprot.org/uniprot/E8UY26 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/401053:ACIPR4_RS15160 ^@ http://purl.uniprot.org/uniprot/E8V5Z0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/401053:ACIPR4_RS10910 ^@ http://purl.uniprot.org/uniprot/E8V8L3 ^@ Caution|||Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/401053:ACIPR4_RS16140 ^@ http://purl.uniprot.org/uniprot/E8V819 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/401053:ACIPR4_RS03760 ^@ http://purl.uniprot.org/uniprot/E8V6C0 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/401053:ACIPR4_RS20000 ^@ http://purl.uniprot.org/uniprot/E8V3R9 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/401053:ACIPR4_RS04210 ^@ http://purl.uniprot.org/uniprot/E8V735 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS15985 ^@ http://purl.uniprot.org/uniprot/E8V7J5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/401053:ACIPR4_RS05315 ^@ http://purl.uniprot.org/uniprot/E8UX09 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/401053:ACIPR4_RS17580 ^@ http://purl.uniprot.org/uniprot/E8UYR7 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/401053:ACIPR4_RS02550 ^@ http://purl.uniprot.org/uniprot/E8V3T6 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS05080 ^@ http://purl.uniprot.org/uniprot/E8V8E7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS02295 ^@ http://purl.uniprot.org/uniprot/E8V323 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/401053:ACIPR4_RS10870 ^@ http://purl.uniprot.org/uniprot/E8V8K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS05230 ^@ http://purl.uniprot.org/uniprot/E8UWZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/401053:ACIPR4_RS19565 ^@ http://purl.uniprot.org/uniprot/E8V2X4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS12315 ^@ http://purl.uniprot.org/uniprot/E8UZH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell inner membrane|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/401053:ACIPR4_RS00675 ^@ http://purl.uniprot.org/uniprot/E8UZ35 ^@ Function ^@ Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA. http://togogenome.org/gene/401053:ACIPR4_RS02685 ^@ http://purl.uniprot.org/uniprot/E8V3W3 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/401053:ACIPR4_RS08780 ^@ http://purl.uniprot.org/uniprot/E8V4U3 ^@ Similarity ^@ Belongs to the peptidase M28 family. M28B subfamily. http://togogenome.org/gene/401053:ACIPR4_RS08910 ^@ http://purl.uniprot.org/uniprot/E8V4W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/401053:ACIPR4_RS15580 ^@ http://purl.uniprot.org/uniprot/E8V6U3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell inner membrane|||Probably interacts with PlsX. http://togogenome.org/gene/401053:ACIPR4_RS00650 ^@ http://purl.uniprot.org/uniprot/E8UZ30 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/401053:ACIPR4_RS00715 ^@ http://purl.uniprot.org/uniprot/E8UZ42 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/401053:ACIPR4_RS02500 ^@ http://purl.uniprot.org/uniprot/E8V364 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/401053:ACIPR4_RS20155 ^@ http://purl.uniprot.org/uniprot/E8V4G2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS07610 ^@ http://purl.uniprot.org/uniprot/E8V1R4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS06890 ^@ http://purl.uniprot.org/uniprot/E8V046 ^@ Caution|||Similarity ^@ Belongs to the peptidase S8 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS02240 ^@ http://purl.uniprot.org/uniprot/E8V312 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/401053:ACIPR4_RS03595 ^@ http://purl.uniprot.org/uniprot/E8V5M0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS16060 ^@ http://purl.uniprot.org/uniprot/E8V7L0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/401053:ACIPR4_RS14440 ^@ http://purl.uniprot.org/uniprot/E8V4B7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS07595 ^@ http://purl.uniprot.org/uniprot/E8V1R1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS10220 ^@ http://purl.uniprot.org/uniprot/E8V7E2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/401053:ACIPR4_RS08315 ^@ http://purl.uniprot.org/uniprot/E8V3C3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS06200 ^@ http://purl.uniprot.org/uniprot/E8UYH8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/401053:ACIPR4_RS12810 ^@ http://purl.uniprot.org/uniprot/E8V103 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/401053:ACIPR4_RS05700 ^@ http://purl.uniprot.org/uniprot/E8UXM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/401053:ACIPR4_RS06110 ^@ http://purl.uniprot.org/uniprot/E8UYG0 ^@ Similarity ^@ Belongs to the ice-binding protein family. http://togogenome.org/gene/401053:ACIPR4_RS10305 ^@ http://purl.uniprot.org/uniprot/E8V7U8 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/401053:ACIPR4_RS04750 ^@ http://purl.uniprot.org/uniprot/E8V880 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS09700 ^@ http://purl.uniprot.org/uniprot/E8V6L3 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS04600 ^@ http://purl.uniprot.org/uniprot/E8V7Q5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. http://togogenome.org/gene/401053:ACIPR4_RS05720 ^@ http://purl.uniprot.org/uniprot/E8UXN1 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS10785 ^@ http://purl.uniprot.org/uniprot/E8V8I8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS01015 ^@ http://purl.uniprot.org/uniprot/E8UZX0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS08870 ^@ http://purl.uniprot.org/uniprot/E8V4W1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS12420 ^@ http://purl.uniprot.org/uniprot/E8UZJ7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/401053:ACIPR4_RS02385 ^@ http://purl.uniprot.org/uniprot/E8V341 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/401053:ACIPR4_RS17660 ^@ http://purl.uniprot.org/uniprot/E8UYT3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS11400 ^@ http://purl.uniprot.org/uniprot/E8UXS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS02085 ^@ http://purl.uniprot.org/uniprot/E8V2C4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/401053:ACIPR4_RS09980 ^@ http://purl.uniprot.org/uniprot/E8V795 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS10180 ^@ http://purl.uniprot.org/uniprot/E8V7D4 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/401053:ACIPR4_RS10120 ^@ http://purl.uniprot.org/uniprot/E8V7C2 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS00900 ^@ http://purl.uniprot.org/uniprot/E8UZU6 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS05075 ^@ http://purl.uniprot.org/uniprot/E8V8E6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/401053:ACIPR4_RS21310 ^@ http://purl.uniprot.org/uniprot/E8V6Z8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/401053:ACIPR4_RS00410 ^@ http://purl.uniprot.org/uniprot/E8UYX7 ^@ Function|||Similarity ^@ Belongs to the transposase IS30 family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/401053:ACIPR4_RS19865 ^@ http://purl.uniprot.org/uniprot/E8V3P2 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/401053:ACIPR4_RS00405 ^@ http://purl.uniprot.org/uniprot/E8UYX6 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/401053:ACIPR4_RS17955 ^@ http://purl.uniprot.org/uniprot/E8UZL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS12040 ^@ http://purl.uniprot.org/uniprot/E8UYQ1 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS04075 ^@ http://purl.uniprot.org/uniprot/E8V707 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS04900 ^@ http://purl.uniprot.org/uniprot/E8V8B3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/401053:ACIPR4_RS18470 ^@ http://purl.uniprot.org/uniprot/E8V0H6 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/401053:ACIPR4_RS12340 ^@ http://purl.uniprot.org/uniprot/E8UZI1 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/401053:ACIPR4_RS19720 ^@ http://purl.uniprot.org/uniprot/E8V3L3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/401053:ACIPR4_RS02575 ^@ http://purl.uniprot.org/uniprot/E8V3U1 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/401053:ACIPR4_RS07605 ^@ http://purl.uniprot.org/uniprot/E8V1R3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS08630 ^@ http://purl.uniprot.org/uniprot/E8V452 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS09225 ^@ http://purl.uniprot.org/uniprot/E8V5Q1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS06300 ^@ http://purl.uniprot.org/uniprot/E8UZ68 ^@ Similarity ^@ Belongs to the HSP15 family. http://togogenome.org/gene/401053:ACIPR4_RS20770 ^@ http://purl.uniprot.org/uniprot/E8V5F4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.|||Belongs to the aromatic-ring hydroxylase family. TetX subfamily.|||Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS18130 ^@ http://purl.uniprot.org/uniprot/E8UZP9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS04635 ^@ http://purl.uniprot.org/uniprot/E8V7R2 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/401053:ACIPR4_RS03605 ^@ http://purl.uniprot.org/uniprot/E8V5M2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS08470 ^@ http://purl.uniprot.org/uniprot/E8V420 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/401053:ACIPR4_RS02455 ^@ http://purl.uniprot.org/uniprot/E8V355 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS01335 ^@ http://purl.uniprot.org/uniprot/E8V0Q0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS09850 ^@ http://purl.uniprot.org/uniprot/E8V6P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS04415 ^@ http://purl.uniprot.org/uniprot/E8V7L9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/401053:ACIPR4_RS20810 ^@ http://purl.uniprot.org/uniprot/E8V631 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS17805 ^@ http://purl.uniprot.org/uniprot/E8UYW1 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/401053:ACIPR4_RS16205 ^@ http://purl.uniprot.org/uniprot/E8V834 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/401053:ACIPR4_RS09855 ^@ http://purl.uniprot.org/uniprot/E8V6P3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS06690 ^@ http://purl.uniprot.org/uniprot/E8V007 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/401053:ACIPR4_RS17190 ^@ http://purl.uniprot.org/uniprot/E8UXX4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/401053:ACIPR4_RS15370 ^@ http://purl.uniprot.org/uniprot/E8V6P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta sliding clamp family.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS13130 ^@ http://purl.uniprot.org/uniprot/E8V168 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/401053:ACIPR4_RS04820 ^@ http://purl.uniprot.org/uniprot/E8V894 ^@ Cofactor|||Similarity ^@ Belongs to the ApbE family.|||Magnesium. Can also use manganese. http://togogenome.org/gene/401053:ACIPR4_RS13580 ^@ http://purl.uniprot.org/uniprot/E8V2M8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS09835 ^@ http://purl.uniprot.org/uniprot/E8V6N9 ^@ Similarity ^@ Belongs to the PdxS/SNZ family. http://togogenome.org/gene/401053:ACIPR4_RS11265 ^@ http://purl.uniprot.org/uniprot/E8UXA0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS03720 ^@ http://purl.uniprot.org/uniprot/E8V6B2 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/401053:ACIPR4_RS17620 ^@ http://purl.uniprot.org/uniprot/E8UYS5 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/401053:ACIPR4_RS20250 ^@ http://purl.uniprot.org/uniprot/E8V4I2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS09280 ^@ http://purl.uniprot.org/uniprot/E8V5R2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS21190 ^@ http://purl.uniprot.org/uniprot/E8V6X2 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/401053:ACIPR4_RS08625 ^@ http://purl.uniprot.org/uniprot/E8V451 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS12865 ^@ http://purl.uniprot.org/uniprot/E8V114 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/401053:ACIPR4_RS18260 ^@ http://purl.uniprot.org/uniprot/E8V0D5 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/401053:ACIPR4_RS05035 ^@ http://purl.uniprot.org/uniprot/E8V8E0 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/401053:ACIPR4_RS12335 ^@ http://purl.uniprot.org/uniprot/E8UZI0 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/401053:ACIPR4_RS02415 ^@ http://purl.uniprot.org/uniprot/E8V347 ^@ Similarity ^@ Belongs to the XFP family. http://togogenome.org/gene/401053:ACIPR4_RS15970 ^@ http://purl.uniprot.org/uniprot/E8V7J2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/401053:ACIPR4_RS06935 ^@ http://purl.uniprot.org/uniprot/E8V056 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/401053:ACIPR4_RS18045 ^@ http://purl.uniprot.org/uniprot/E8UZN3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS16215 ^@ http://purl.uniprot.org/uniprot/E8V836 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/401053:ACIPR4_RS01535 ^@ http://purl.uniprot.org/uniprot/E8V1F6 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/401053:ACIPR4_RS10245 ^@ http://purl.uniprot.org/uniprot/E8V7T6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/401053:ACIPR4_RS19630 ^@ http://purl.uniprot.org/uniprot/E8V2Y6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS16970 ^@ http://purl.uniprot.org/uniprot/E8UXE6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/401053:ACIPR4_RS17195 ^@ http://purl.uniprot.org/uniprot/E8UXX5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/401053:ACIPR4_RS12375 ^@ http://purl.uniprot.org/uniprot/E8UZI8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/401053:ACIPR4_RS16955 ^@ http://purl.uniprot.org/uniprot/E8UXE3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family. http://togogenome.org/gene/401053:ACIPR4_RS20745 ^@ http://purl.uniprot.org/uniprot/E8V5E9 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/401053:ACIPR4_RS12280 ^@ http://purl.uniprot.org/uniprot/E8UZG9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/401053:ACIPR4_RS06025 ^@ http://purl.uniprot.org/uniprot/E8UYE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS08585 ^@ http://purl.uniprot.org/uniprot/E8V443 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/401053:ACIPR4_RS18815 ^@ http://purl.uniprot.org/uniprot/E8V1B1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/401053:ACIPR4_RS13820 ^@ http://purl.uniprot.org/uniprot/E8V2S5 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/401053:ACIPR4_RS18055 ^@ http://purl.uniprot.org/uniprot/E8UZN5 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS08560 ^@ http://purl.uniprot.org/uniprot/E8V438 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS10215 ^@ http://purl.uniprot.org/uniprot/E8V7E1 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/401053:ACIPR4_RS11670 ^@ http://purl.uniprot.org/uniprot/E8UXW6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS21180 ^@ http://purl.uniprot.org/uniprot/E8V6X0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS20960 ^@ http://purl.uniprot.org/uniprot/E8V660 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/401053:ACIPR4_RS00885 ^@ http://purl.uniprot.org/uniprot/E8UZU3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS17740 ^@ http://purl.uniprot.org/uniprot/E8UYU8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/401053:ACIPR4_RS01915 ^@ http://purl.uniprot.org/uniprot/E8V290 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/401053:ACIPR4_RS04890 ^@ http://purl.uniprot.org/uniprot/E8V8B1 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/401053:ACIPR4_RS10145 ^@ http://purl.uniprot.org/uniprot/E8V7C7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS03885 ^@ http://purl.uniprot.org/uniprot/E8V6E5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS12925 ^@ http://purl.uniprot.org/uniprot/E8V126 ^@ Similarity ^@ Belongs to the peptidase M42 family. http://togogenome.org/gene/401053:ACIPR4_RS06435 ^@ http://purl.uniprot.org/uniprot/E8UZ92 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS13985 ^@ http://purl.uniprot.org/uniprot/E8V3H0 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/401053:ACIPR4_RS04530 ^@ http://purl.uniprot.org/uniprot/E8V7P2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS06405 ^@ http://purl.uniprot.org/uniprot/E8UZ86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS13915 ^@ http://purl.uniprot.org/uniprot/E8V3F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS05355 ^@ http://purl.uniprot.org/uniprot/E8UX17 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS03985 ^@ http://purl.uniprot.org/uniprot/E8V6G4 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/401053:ACIPR4_RS03280 ^@ http://purl.uniprot.org/uniprot/E8V4T9 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/401053:ACIPR4_RS15890 ^@ http://purl.uniprot.org/uniprot/E8V7H7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/401053:ACIPR4_RS12545 ^@ http://purl.uniprot.org/uniprot/E8V081 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS04895 ^@ http://purl.uniprot.org/uniprot/E8V8B2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/401053:ACIPR4_RS14835 ^@ http://purl.uniprot.org/uniprot/E8V556 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/401053:ACIPR4_RS01010 ^@ http://purl.uniprot.org/uniprot/E8UZW9 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS14860 ^@ http://purl.uniprot.org/uniprot/E8V561 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS18305 ^@ http://purl.uniprot.org/uniprot/E8V0E5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/401053:ACIPR4_RS13290 ^@ http://purl.uniprot.org/uniprot/E8V1V9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS10230 ^@ http://purl.uniprot.org/uniprot/E8V7T3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS17765 ^@ http://purl.uniprot.org/uniprot/E8UYV3 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/401053:ACIPR4_RS01845 ^@ http://purl.uniprot.org/uniprot/E8V276 ^@ Similarity ^@ Belongs to the pseudouridine synthase RluA family. http://togogenome.org/gene/401053:ACIPR4_RS17060 ^@ http://purl.uniprot.org/uniprot/E8UXG5 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/401053:ACIPR4_RS06625 ^@ http://purl.uniprot.org/uniprot/E8UZZ4 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/401053:ACIPR4_RS03575 ^@ http://purl.uniprot.org/uniprot/E8V5L6 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/401053:ACIPR4_RS07825 ^@ http://purl.uniprot.org/uniprot/E8V2H1 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS17960 ^@ http://purl.uniprot.org/uniprot/E8UZL6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS18135 ^@ http://purl.uniprot.org/uniprot/E8UZQ0 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/401053:ACIPR4_RS02545 ^@ http://purl.uniprot.org/uniprot/E8V374 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS16115 ^@ http://purl.uniprot.org/uniprot/E8V813 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS05705 ^@ http://purl.uniprot.org/uniprot/E8UXM8 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS02705 ^@ http://purl.uniprot.org/uniprot/E8V3W7 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/401053:ACIPR4_RS02140 ^@ http://purl.uniprot.org/uniprot/E8V2D5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/401053:ACIPR4_RS21095 ^@ http://purl.uniprot.org/uniprot/E8V687 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS17570 ^@ http://purl.uniprot.org/uniprot/E8UYR5 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/401053:ACIPR4_RS01065 ^@ http://purl.uniprot.org/uniprot/E8UZY0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/401053:ACIPR4_RS19910 ^@ http://purl.uniprot.org/uniprot/E8V3Q1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS16610 ^@ http://purl.uniprot.org/uniprot/E8V8Q9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS11940 ^@ http://purl.uniprot.org/uniprot/E8UYN1 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/401053:ACIPR4_RS02260 ^@ http://purl.uniprot.org/uniprot/E8V317 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS06620 ^@ http://purl.uniprot.org/uniprot/E8UZZ3 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/401053:ACIPR4_RS21555 ^@ http://purl.uniprot.org/uniprot/E8V2G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/401053:ACIPR4_RS08950 ^@ http://purl.uniprot.org/uniprot/E8V4X7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/401053:ACIPR4_RS00990 ^@ http://purl.uniprot.org/uniprot/E8UZW5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS03070 ^@ http://purl.uniprot.org/uniprot/E8V4P8 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/401053:ACIPR4_RS04005 ^@ http://purl.uniprot.org/uniprot/E8V6G8 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/401053:ACIPR4_RS18245 ^@ http://purl.uniprot.org/uniprot/E8V0D2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS11665 ^@ http://purl.uniprot.org/uniprot/E8UXW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS12305 ^@ http://purl.uniprot.org/uniprot/E8UZH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS09805 ^@ http://purl.uniprot.org/uniprot/E8V6N3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer.|||In the N-terminal section; belongs to the DHBP synthase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS04760 ^@ http://purl.uniprot.org/uniprot/E8V882 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS03120 ^@ http://purl.uniprot.org/uniprot/E8V4Q7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS14590 ^@ http://purl.uniprot.org/uniprot/E8V4E6 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/401053:ACIPR4_RS05235 ^@ http://purl.uniprot.org/uniprot/E8UWZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/401053:ACIPR4_RS15515 ^@ http://purl.uniprot.org/uniprot/E8V6T0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/401053:ACIPR4_RS06245 ^@ http://purl.uniprot.org/uniprot/E8UZ57 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/401053:ACIPR4_RS09245 ^@ http://purl.uniprot.org/uniprot/E8V5Q5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS03365 ^@ http://purl.uniprot.org/uniprot/E8V5H6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/401053:ACIPR4_RS16530 ^@ http://purl.uniprot.org/uniprot/E8V8P3 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/401053:ACIPR4_RS06355 ^@ http://purl.uniprot.org/uniprot/E8UZ76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/401053:ACIPR4_RS08375 ^@ http://purl.uniprot.org/uniprot/E8V3D5 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/401053:ACIPR4_RS02565 ^@ http://purl.uniprot.org/uniprot/E8V3T9 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/401053:ACIPR4_RS01360 ^@ http://purl.uniprot.org/uniprot/E8V0Q5 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/401053:ACIPR4_RS15290 ^@ http://purl.uniprot.org/uniprot/E8V615 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/401053:ACIPR4_RS16165 ^@ http://purl.uniprot.org/uniprot/E8V826 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS10690 ^@ http://purl.uniprot.org/uniprot/E8V8G9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/401053:ACIPR4_RS05640 ^@ http://purl.uniprot.org/uniprot/E8UXL5 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/401053:ACIPR4_RS08430 ^@ http://purl.uniprot.org/uniprot/E8V412 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/401053:ACIPR4_RS18165 ^@ http://purl.uniprot.org/uniprot/E8UZQ6 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/401053:ACIPR4_RS18545 ^@ http://purl.uniprot.org/uniprot/E8V0J1 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell inner membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/401053:ACIPR4_RS03745 ^@ http://purl.uniprot.org/uniprot/E8V6B7 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/401053:ACIPR4_RS06345 ^@ http://purl.uniprot.org/uniprot/E8UZ74 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/401053:ACIPR4_RS03795 ^@ http://purl.uniprot.org/uniprot/E8V6C7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS12360 ^@ http://purl.uniprot.org/uniprot/E8UZI5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/401053:ACIPR4_RS19705 ^@ http://purl.uniprot.org/uniprot/E8V300 ^@ Caution|||Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS03220 ^@ http://purl.uniprot.org/uniprot/E8V4S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS21320 ^@ http://purl.uniprot.org/uniprot/E8UY92 ^@ Similarity ^@ Belongs to the cysteine dioxygenase family. http://togogenome.org/gene/401053:ACIPR4_RS16020 ^@ http://purl.uniprot.org/uniprot/E8V7K2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/401053:ACIPR4_RS13100 ^@ http://purl.uniprot.org/uniprot/E8V162 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS13835 ^@ http://purl.uniprot.org/uniprot/E8V2S8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/401053:ACIPR4_RS04040 ^@ http://purl.uniprot.org/uniprot/E8V700 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS05100 ^@ http://purl.uniprot.org/uniprot/E8UWW7 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/401053:ACIPR4_RS04770 ^@ http://purl.uniprot.org/uniprot/E8V884 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/401053:ACIPR4_RS21165 ^@ http://purl.uniprot.org/uniprot/E8V6W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS15255 ^@ http://purl.uniprot.org/uniprot/E8V608 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/401053:ACIPR4_RS20015 ^@ http://purl.uniprot.org/uniprot/E8V3S2 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/401053:ACIPR4_RS15185 ^@ http://purl.uniprot.org/uniprot/E8V5Z4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/401053:ACIPR4_RS03095 ^@ http://purl.uniprot.org/uniprot/E8V4Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS08740 ^@ http://purl.uniprot.org/uniprot/E8V474 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS02770 ^@ http://purl.uniprot.org/uniprot/E8V3Y0 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS11955 ^@ http://purl.uniprot.org/uniprot/E8UYN4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/401053:ACIPR4_RS21600 ^@ http://purl.uniprot.org/uniprot/E8V6K1 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/401053:ACIPR4_RS16315 ^@ http://purl.uniprot.org/uniprot/E8V855 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS04990 ^@ http://purl.uniprot.org/uniprot/E8V8D1 ^@ Similarity ^@ Belongs to the MQO family. http://togogenome.org/gene/401053:ACIPR4_RS09590 ^@ http://purl.uniprot.org/uniprot/E8V6J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS13930 ^@ http://purl.uniprot.org/uniprot/E8V3F9 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/401053:ACIPR4_RS13060 ^@ http://purl.uniprot.org/uniprot/E8V155 ^@ Similarity ^@ Belongs to the helicase family. RecG subfamily. http://togogenome.org/gene/401053:ACIPR4_RS16985 ^@ http://purl.uniprot.org/uniprot/E8UXE9 ^@ Function|||Similarity ^@ Belongs to the transposase IS30 family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/401053:ACIPR4_RS11165 ^@ http://purl.uniprot.org/uniprot/E8UX80 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS05040 ^@ http://purl.uniprot.org/uniprot/E8V8E1 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/401053:ACIPR4_RS16075 ^@ http://purl.uniprot.org/uniprot/E8V805 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/401053:ACIPR4_RS08160 ^@ http://purl.uniprot.org/uniprot/E8V396 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/401053:ACIPR4_RS12485 ^@ http://purl.uniprot.org/uniprot/E8V069 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS19645 ^@ http://purl.uniprot.org/uniprot/E8V2Y9 ^@ Function|||Similarity ^@ Belongs to the catalase family. HPII subfamily.|||Serves to protect cells from the toxic effects of hydrogen peroxide. http://togogenome.org/gene/401053:ACIPR4_RS00290 ^@ http://purl.uniprot.org/uniprot/E8UY88 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/401053:ACIPR4_RS04780 ^@ http://purl.uniprot.org/uniprot/E8V886 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/401053:ACIPR4_RS03015 ^@ http://purl.uniprot.org/uniprot/E8V4N7 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/401053:ACIPR4_RS21205 ^@ http://purl.uniprot.org/uniprot/E8V6X5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell inner membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/401053:ACIPR4_RS16240 ^@ http://purl.uniprot.org/uniprot/E8V841 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS17110 ^@ http://purl.uniprot.org/uniprot/E8UXH3 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/401053:ACIPR4_RS09630 ^@ http://purl.uniprot.org/uniprot/E8V6J9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/401053:ACIPR4_RS15175 ^@ http://purl.uniprot.org/uniprot/E8V5Z2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS12655 ^@ http://purl.uniprot.org/uniprot/E8V0A3 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/401053:ACIPR4_RS17115 ^@ http://purl.uniprot.org/uniprot/E8UXH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/401053:ACIPR4_RS10470 ^@ http://purl.uniprot.org/uniprot/E8V7Y0 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS17050 ^@ http://purl.uniprot.org/uniprot/E8UXG3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS00245 ^@ http://purl.uniprot.org/uniprot/E8UY79 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS16515 ^@ http://purl.uniprot.org/uniprot/E8V8N9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/401053:ACIPR4_RS04320 ^@ http://purl.uniprot.org/uniprot/E8V757 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS20805 ^@ http://purl.uniprot.org/uniprot/E8V630 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/401053:ACIPR4_RS06995 ^@ http://purl.uniprot.org/uniprot/E8V0T3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS10240 ^@ http://purl.uniprot.org/uniprot/E8V7T5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS05735 ^@ http://purl.uniprot.org/uniprot/E8UXN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS07010 ^@ http://purl.uniprot.org/uniprot/E8V0T6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/401053:ACIPR4_RS17370 ^@ http://purl.uniprot.org/uniprot/E8UY09 ^@ Similarity ^@ Belongs to the aminoglycoside phosphotransferase family.|||Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/401053:ACIPR4_RS13075 ^@ http://purl.uniprot.org/uniprot/E8V158 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily. http://togogenome.org/gene/401053:ACIPR4_RS12260 ^@ http://purl.uniprot.org/uniprot/E8UZG5 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/401053:ACIPR4_RS04435 ^@ http://purl.uniprot.org/uniprot/E8V7M3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.|||Cell inner membrane|||Intake of glucose and galactose.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS03480 ^@ http://purl.uniprot.org/uniprot/E8V5J8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/401053:ACIPR4_RS09165 ^@ http://purl.uniprot.org/uniprot/E8V5N9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 10 (cellulase F) family. http://togogenome.org/gene/401053:ACIPR4_RS15150 ^@ http://purl.uniprot.org/uniprot/E8V5Y8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/401053:ACIPR4_RS20520 ^@ http://purl.uniprot.org/uniprot/E8V5A1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/401053:ACIPR4_RS19040 ^@ http://purl.uniprot.org/uniprot/E8V213 ^@ Similarity ^@ Belongs to the aconitase/IPM isomerase family. http://togogenome.org/gene/401053:ACIPR4_RS00730 ^@ http://purl.uniprot.org/uniprot/E8UZ45 ^@ Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family. http://togogenome.org/gene/401053:ACIPR4_RS05740 ^@ http://purl.uniprot.org/uniprot/E8UXN5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS15770 ^@ http://purl.uniprot.org/uniprot/E8V7F2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS02505 ^@ http://purl.uniprot.org/uniprot/E8V365 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS14780 ^@ http://purl.uniprot.org/uniprot/E8V545 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS09470 ^@ http://purl.uniprot.org/uniprot/E8V5V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YtcA family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS03455 ^@ http://purl.uniprot.org/uniprot/E8V5J3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/401053:ACIPR4_RS09620 ^@ http://purl.uniprot.org/uniprot/E8V6J7 ^@ Similarity ^@ Belongs to the DNase II family. http://togogenome.org/gene/401053:ACIPR4_RS16280 ^@ http://purl.uniprot.org/uniprot/E8V849 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/401053:ACIPR4_RS21100 ^@ http://purl.uniprot.org/uniprot/E8V688 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/401053:ACIPR4_RS12240 ^@ http://purl.uniprot.org/uniprot/E8UZG1 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS07785 ^@ http://purl.uniprot.org/uniprot/E8V2G3 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/401053:ACIPR4_RS15240 ^@ http://purl.uniprot.org/uniprot/E8V605 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS15245 ^@ http://purl.uniprot.org/uniprot/E8V606 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS00630 ^@ http://purl.uniprot.org/uniprot/E8UZ26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS03900 ^@ http://purl.uniprot.org/uniprot/E8V6E7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/401053:ACIPR4_RS03290 ^@ http://purl.uniprot.org/uniprot/E8V5G1 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/401053:ACIPR4_RS20705 ^@ http://purl.uniprot.org/uniprot/E8V5E2 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/401053:ACIPR4_RS04350 ^@ http://purl.uniprot.org/uniprot/E8V764 ^@ Similarity ^@ Belongs to the MreC family. http://togogenome.org/gene/401053:ACIPR4_RS15955 ^@ http://purl.uniprot.org/uniprot/E8V7I9 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/401053:ACIPR4_RS08245 ^@ http://purl.uniprot.org/uniprot/E8V3A8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/401053:ACIPR4_RS05875 ^@ http://purl.uniprot.org/uniprot/E8UYB9 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/401053:ACIPR4_RS15980 ^@ http://purl.uniprot.org/uniprot/E8V7J4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/401053:ACIPR4_RS00755 ^@ http://purl.uniprot.org/uniprot/E8UZ50 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/401053:ACIPR4_RS01805 ^@ http://purl.uniprot.org/uniprot/E8V1K6 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS05210 ^@ http://purl.uniprot.org/uniprot/E8UWY8 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS00205 ^@ http://purl.uniprot.org/uniprot/E8UY72 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/401053:ACIPR4_RS13750 ^@ http://purl.uniprot.org/uniprot/E8V2R2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 39 family. http://togogenome.org/gene/401053:ACIPR4_RS07425 ^@ http://purl.uniprot.org/uniprot/E8V1M8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS19485 ^@ http://purl.uniprot.org/uniprot/E8V2V9 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS16265 ^@ http://purl.uniprot.org/uniprot/E8V846 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS03990 ^@ http://purl.uniprot.org/uniprot/E8V6G5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/401053:ACIPR4_RS06775 ^@ http://purl.uniprot.org/uniprot/E8V023 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS20615 ^@ http://purl.uniprot.org/uniprot/E8V5C3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/401053:ACIPR4_RS08795 ^@ http://purl.uniprot.org/uniprot/E8V4U6 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/401053:ACIPR4_RS12285 ^@ http://purl.uniprot.org/uniprot/E8UZH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/401053:ACIPR4_RS21300 ^@ http://purl.uniprot.org/uniprot/E8V6Z6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell inner membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/401053:ACIPR4_RS19205 ^@ http://purl.uniprot.org/uniprot/E8V246 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS15235 ^@ http://purl.uniprot.org/uniprot/E8V604 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/401053:ACIPR4_RS01790 ^@ http://purl.uniprot.org/uniprot/E8V1K3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/401053:ACIPR4_RS10360 ^@ http://purl.uniprot.org/uniprot/E8V7W0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS04910 ^@ http://purl.uniprot.org/uniprot/E8V8B5 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family. http://togogenome.org/gene/401053:ACIPR4_RS15990 ^@ http://purl.uniprot.org/uniprot/E8V7J6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/401053:ACIPR4_RS05635 ^@ http://purl.uniprot.org/uniprot/E8UXL4 ^@ Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Dimer of large and small chains. http://togogenome.org/gene/401053:ACIPR4_RS18870 ^@ http://purl.uniprot.org/uniprot/E8V1C1 ^@ Function|||Similarity ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. http://togogenome.org/gene/401053:ACIPR4_RS15330 ^@ http://purl.uniprot.org/uniprot/E8V624 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/401053:ACIPR4_RS17745 ^@ http://purl.uniprot.org/uniprot/E8UYU9 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/401053:ACIPR4_RS08885 ^@ http://purl.uniprot.org/uniprot/E8V4W4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS08455 ^@ http://purl.uniprot.org/uniprot/E8V417 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS22980 ^@ http://purl.uniprot.org/uniprot/E8V6Q0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/401053:ACIPR4_RS06840 ^@ http://purl.uniprot.org/uniprot/E8V036 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/401053:ACIPR4_RS16935 ^@ http://purl.uniprot.org/uniprot/E8UXD8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/401053:ACIPR4_RS08775 ^@ http://purl.uniprot.org/uniprot/E8V4U2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. http://togogenome.org/gene/401053:ACIPR4_RS05810 ^@ http://purl.uniprot.org/uniprot/E8UXP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS06760 ^@ http://purl.uniprot.org/uniprot/E8V020 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS18615 ^@ http://purl.uniprot.org/uniprot/E8V173 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/401053:ACIPR4_RS05000 ^@ http://purl.uniprot.org/uniprot/E8V8D3 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/401053:ACIPR4_RS07855 ^@ http://purl.uniprot.org/uniprot/E8V2H7 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/401053:ACIPR4_RS05560 ^@ http://purl.uniprot.org/uniprot/E8UXJ9 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/401053:ACIPR4_RS06540 ^@ http://purl.uniprot.org/uniprot/E8UZB2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS02020 ^@ http://purl.uniprot.org/uniprot/E8V2B1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. http://togogenome.org/gene/401053:ACIPR4_RS19690 ^@ http://purl.uniprot.org/uniprot/E8V2Z8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/401053:ACIPR4_RS19315 ^@ http://purl.uniprot.org/uniprot/E8V267 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/401053:ACIPR4_RS17755 ^@ http://purl.uniprot.org/uniprot/E8UYV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS05790 ^@ http://purl.uniprot.org/uniprot/E8UXP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS18905 ^@ http://purl.uniprot.org/uniprot/E8V1C8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS09010 ^@ http://purl.uniprot.org/uniprot/E8V4Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/401053:ACIPR4_RS03035 ^@ http://purl.uniprot.org/uniprot/E8V4P1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell inner membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/401053:ACIPR4_RS15340 ^@ http://purl.uniprot.org/uniprot/E8V626 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. C-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/401053:ACIPR4_RS07275 ^@ http://purl.uniprot.org/uniprot/E8V0Y8 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/401053:ACIPR4_RS02635 ^@ http://purl.uniprot.org/uniprot/E8V3V3 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/401053:ACIPR4_RS08725 ^@ http://purl.uniprot.org/uniprot/E8V470 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS03130 ^@ http://purl.uniprot.org/uniprot/E8V4Q9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/401053:ACIPR4_RS15635 ^@ http://purl.uniprot.org/uniprot/E8V6V4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/401053:ACIPR4_RS12470 ^@ http://purl.uniprot.org/uniprot/E8V066 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily. http://togogenome.org/gene/401053:ACIPR4_RS13385 ^@ http://purl.uniprot.org/uniprot/E8V1X8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS21020 ^@ http://purl.uniprot.org/uniprot/E8V672 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS03010 ^@ http://purl.uniprot.org/uniprot/E8V4N6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS01995 ^@ http://purl.uniprot.org/uniprot/E8V2A6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/401053:ACIPR4_RS04055 ^@ http://purl.uniprot.org/uniprot/E8V703 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS06825 ^@ http://purl.uniprot.org/uniprot/E8V033 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/401053:ACIPR4_RS04395 ^@ http://purl.uniprot.org/uniprot/E8V7L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS20245 ^@ http://purl.uniprot.org/uniprot/E8V4I1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS21895 ^@ http://purl.uniprot.org/uniprot/E8V0J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS19960 ^@ http://purl.uniprot.org/uniprot/E8V3R1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS10650 ^@ http://purl.uniprot.org/uniprot/E8V8G1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/401053:ACIPR4_RS05870 ^@ http://purl.uniprot.org/uniprot/E8UYB8 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/401053:ACIPR4_RS01260 ^@ http://purl.uniprot.org/uniprot/E8V0N4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS12325 ^@ http://purl.uniprot.org/uniprot/E8UZH8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/401053:ACIPR4_RS16770 ^@ http://purl.uniprot.org/uniprot/E8V8U1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS01205 ^@ http://purl.uniprot.org/uniprot/E8V0M3 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/401053:ACIPR4_RS04270 ^@ http://purl.uniprot.org/uniprot/E8V747 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM175 family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS15740 ^@ http://purl.uniprot.org/uniprot/E8V7E6 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/401053:ACIPR4_RS15585 ^@ http://purl.uniprot.org/uniprot/E8V6U4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS00010 ^@ http://purl.uniprot.org/uniprot/E8UXH9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/401053:ACIPR4_RS19085 ^@ http://purl.uniprot.org/uniprot/E8V223 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. http://togogenome.org/gene/401053:ACIPR4_RS10515 ^@ http://purl.uniprot.org/uniprot/E8V7Y9 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/401053:ACIPR4_RS20030 ^@ http://purl.uniprot.org/uniprot/E8V3S5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/401053:ACIPR4_RS04935 ^@ http://purl.uniprot.org/uniprot/E8V8C0 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/401053:ACIPR4_RS19970 ^@ http://purl.uniprot.org/uniprot/E8V3R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/401053:ACIPR4_RS03545 ^@ http://purl.uniprot.org/uniprot/E8V5L0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/401053:ACIPR4_RS20010 ^@ http://purl.uniprot.org/uniprot/E8V3S1 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/401053:ACIPR4_RS01235 ^@ http://purl.uniprot.org/uniprot/E8V0M9 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/401053:ACIPR4_RS07510 ^@ http://purl.uniprot.org/uniprot/E8V1P5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/401053:ACIPR4_RS04665 ^@ http://purl.uniprot.org/uniprot/E8V7R8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/401053:ACIPR4_RS06700 ^@ http://purl.uniprot.org/uniprot/E8V009 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS09125 ^@ http://purl.uniprot.org/uniprot/E8V5N1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family. http://togogenome.org/gene/401053:ACIPR4_RS10865 ^@ http://purl.uniprot.org/uniprot/E8V8K4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS12295 ^@ http://purl.uniprot.org/uniprot/E8UZH2 ^@ Similarity ^@ Belongs to the OprB family. http://togogenome.org/gene/401053:ACIPR4_RS11285 ^@ http://purl.uniprot.org/uniprot/E8UXA4 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS12430 ^@ http://purl.uniprot.org/uniprot/E8V061 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS10875 ^@ http://purl.uniprot.org/uniprot/E8V8K6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/401053:ACIPR4_RS05310 ^@ http://purl.uniprot.org/uniprot/E8UX08 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/401053:ACIPR4_RS16105 ^@ http://purl.uniprot.org/uniprot/E8V811 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/401053:ACIPR4_RS21065 ^@ http://purl.uniprot.org/uniprot/E8V681 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum|||Golgi apparatus|||Lysosome http://togogenome.org/gene/401053:ACIPR4_RS18220 ^@ http://purl.uniprot.org/uniprot/E8UZR7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS15500 ^@ http://purl.uniprot.org/uniprot/E8V6S7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/401053:ACIPR4_RS01785 ^@ http://purl.uniprot.org/uniprot/E8V1K2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/401053:ACIPR4_RS16625 ^@ http://purl.uniprot.org/uniprot/E8V8R2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/401053:ACIPR4_RS03585 ^@ http://purl.uniprot.org/uniprot/E8V5L8 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/401053:ACIPR4_RS17225 ^@ http://purl.uniprot.org/uniprot/E8UXY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS19810 ^@ http://purl.uniprot.org/uniprot/E8V3N1 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/401053:ACIPR4_RS18150 ^@ http://purl.uniprot.org/uniprot/E8UZQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS17355 ^@ http://purl.uniprot.org/uniprot/E8UY06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS05930 ^@ http://purl.uniprot.org/uniprot/E8UYD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS03785 ^@ http://purl.uniprot.org/uniprot/E8V6C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS05675 ^@ http://purl.uniprot.org/uniprot/E8UXM2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/401053:ACIPR4_RS03315 ^@ http://purl.uniprot.org/uniprot/E8V5G6 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS06615 ^@ http://purl.uniprot.org/uniprot/E8UZZ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/401053:ACIPR4_RS14865 ^@ http://purl.uniprot.org/uniprot/E8V562 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/401053:ACIPR4_RS20515 ^@ http://purl.uniprot.org/uniprot/E8V5A0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/401053:ACIPR4_RS03445 ^@ http://purl.uniprot.org/uniprot/E8V5J1 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/401053:ACIPR4_RS12795 ^@ http://purl.uniprot.org/uniprot/E8V100 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS12770 ^@ http://purl.uniprot.org/uniprot/E8V0C5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/401053:ACIPR4_RS20495 ^@ http://purl.uniprot.org/uniprot/E8V596 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS09685 ^@ http://purl.uniprot.org/uniprot/E8V6L0 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/401053:ACIPR4_RS09090 ^@ http://purl.uniprot.org/uniprot/E8V505 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/401053:ACIPR4_RS21835 ^@ http://purl.uniprot.org/uniprot/E8V8N7 ^@ Similarity ^@ In the N-terminal section; belongs to the phytochrome family. http://togogenome.org/gene/401053:ACIPR4_RS06015 ^@ http://purl.uniprot.org/uniprot/E8UYE2 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/401053:ACIPR4_RS04650 ^@ http://purl.uniprot.org/uniprot/E8V7R5 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/401053:ACIPR4_RS05920 ^@ http://purl.uniprot.org/uniprot/E8UYC8 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/401053:ACIPR4_RS04720 ^@ http://purl.uniprot.org/uniprot/E8V7S9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/401053:ACIPR4_RS04065 ^@ http://purl.uniprot.org/uniprot/E8V705 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GRP transporter (TC 2.A.7.5) family.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS18850 ^@ http://purl.uniprot.org/uniprot/E8V1B7 ^@ Function|||Similarity ^@ Belongs to the transposase IS30 family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/401053:ACIPR4_RS16030 ^@ http://purl.uniprot.org/uniprot/E8V7K4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/401053:ACIPR4_RS07155 ^@ http://purl.uniprot.org/uniprot/E8V0W6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS04470 ^@ http://purl.uniprot.org/uniprot/E8V7N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS04985 ^@ http://purl.uniprot.org/uniprot/E8V8D0 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/401053:ACIPR4_RS19990 ^@ http://purl.uniprot.org/uniprot/E8V3R7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/401053:ACIPR4_RS00930 ^@ http://purl.uniprot.org/uniprot/E8UZV2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS15250 ^@ http://purl.uniprot.org/uniprot/E8V607 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/401053:ACIPR4_RS11205 ^@ http://purl.uniprot.org/uniprot/E8UX88 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS02490 ^@ http://purl.uniprot.org/uniprot/E8V362 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS02605 ^@ http://purl.uniprot.org/uniprot/E8V3U7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/401053:ACIPR4_RS00855 ^@ http://purl.uniprot.org/uniprot/E8UZT7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutC family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/401053:ACIPR4_RS01385 ^@ http://purl.uniprot.org/uniprot/E8V0R0 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/401053:ACIPR4_RS10295 ^@ http://purl.uniprot.org/uniprot/E8V7U6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/401053:ACIPR4_RS03565 ^@ http://purl.uniprot.org/uniprot/E8V5L4 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/401053:ACIPR4_RS08750 ^@ http://purl.uniprot.org/uniprot/E8V476 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/401053:ACIPR4_RS07845 ^@ http://purl.uniprot.org/uniprot/E8V2H5 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/401053:ACIPR4_RS14920 ^@ http://purl.uniprot.org/uniprot/E8V573 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS00705 ^@ http://purl.uniprot.org/uniprot/E8UZ40 ^@ Similarity ^@ Belongs to the ClpX chaperone family. HslU subfamily. http://togogenome.org/gene/401053:ACIPR4_RS07000 ^@ http://purl.uniprot.org/uniprot/E8V0T4 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/401053:ACIPR4_RS21295 ^@ http://purl.uniprot.org/uniprot/E8V6Z5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell inner membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/401053:ACIPR4_RS12905 ^@ http://purl.uniprot.org/uniprot/E8V122 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/401053:ACIPR4_RS12385 ^@ http://purl.uniprot.org/uniprot/E8UZJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell inner membrane|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS02800 ^@ http://purl.uniprot.org/uniprot/E8V3Y5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS00170 ^@ http://purl.uniprot.org/uniprot/E8UY65 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/401053:ACIPR4_RS09555 ^@ http://purl.uniprot.org/uniprot/E8V6I4 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/401053:ACIPR4_RS00155 ^@ http://purl.uniprot.org/uniprot/E8UY62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS10445 ^@ http://purl.uniprot.org/uniprot/E8V7X5 ^@ Function|||Similarity ^@ Belongs to the PqqB family.|||May be involved in the transport of PQQ or its precursor to the periplasm. http://togogenome.org/gene/401053:ACIPR4_RS16400 ^@ http://purl.uniprot.org/uniprot/E8V870 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS00370 ^@ http://purl.uniprot.org/uniprot/E8UYA4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/401053:ACIPR4_RS12365 ^@ http://purl.uniprot.org/uniprot/E8UZI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 5 family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS10750 ^@ http://purl.uniprot.org/uniprot/E8V8I1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS19770 ^@ http://purl.uniprot.org/uniprot/E8V3M3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/401053:ACIPR4_RS20870 ^@ http://purl.uniprot.org/uniprot/E8V642 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS06640 ^@ http://purl.uniprot.org/uniprot/E8UZZ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS08355 ^@ http://purl.uniprot.org/uniprot/E8V3D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS09270 ^@ http://purl.uniprot.org/uniprot/E8V5R0 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/401053:ACIPR4_RS12980 ^@ http://purl.uniprot.org/uniprot/E8V139 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS05925 ^@ http://purl.uniprot.org/uniprot/E8UYC9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS04630 ^@ http://purl.uniprot.org/uniprot/E8V7R1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS01610 ^@ http://purl.uniprot.org/uniprot/E8V1G9 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/401053:ACIPR4_RS06665 ^@ http://purl.uniprot.org/uniprot/E8V002 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS03080 ^@ http://purl.uniprot.org/uniprot/E8V4Q0 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/401053:ACIPR4_RS04405 ^@ http://purl.uniprot.org/uniprot/E8V7L7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/401053:ACIPR4_RS03050 ^@ http://purl.uniprot.org/uniprot/E8V4P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS15975 ^@ http://purl.uniprot.org/uniprot/E8V7J3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/401053:ACIPR4_RS09150 ^@ http://purl.uniprot.org/uniprot/E8V5N6 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/401053:ACIPR4_RS03970 ^@ http://purl.uniprot.org/uniprot/E8V6G1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS13720 ^@ http://purl.uniprot.org/uniprot/E8V2Q6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/401053:ACIPR4_RS19265 ^@ http://purl.uniprot.org/uniprot/E8V257 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/401053:ACIPR4_RS09365 ^@ http://purl.uniprot.org/uniprot/E8V5S8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS15895 ^@ http://purl.uniprot.org/uniprot/E8V7H8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/401053:ACIPR4_RS14585 ^@ http://purl.uniprot.org/uniprot/E8V4E5 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/401053:ACIPR4_RS09945 ^@ http://purl.uniprot.org/uniprot/E8V788 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS20410 ^@ http://purl.uniprot.org/uniprot/E8V4L4 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS10840 ^@ http://purl.uniprot.org/uniprot/E8V8J9 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS04565 ^@ http://purl.uniprot.org/uniprot/E8V7P9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS11795 ^@ http://purl.uniprot.org/uniprot/E8UYK3 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/401053:ACIPR4_RS11485 ^@ http://purl.uniprot.org/uniprot/E8UXT5 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS02485 ^@ http://purl.uniprot.org/uniprot/E8V361 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS19830 ^@ http://purl.uniprot.org/uniprot/E8V3N5 ^@ Function|||Similarity ^@ Belongs to the transposase IS30 family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/401053:ACIPR4_RS10895 ^@ http://purl.uniprot.org/uniprot/E8V8L0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS00685 ^@ http://purl.uniprot.org/uniprot/E8UZ37 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/401053:ACIPR4_RS12265 ^@ http://purl.uniprot.org/uniprot/E8UZG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/401053:ACIPR4_RS17550 ^@ http://purl.uniprot.org/uniprot/E8UYR1 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/401053:ACIPR4_RS00200 ^@ http://purl.uniprot.org/uniprot/E8UY71 ^@ Cofactor ^@ Binds 2 manganese ions per subunit. http://togogenome.org/gene/401053:ACIPR4_RS19435 ^@ http://purl.uniprot.org/uniprot/E8V2U9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/401053:ACIPR4_RS13435 ^@ http://purl.uniprot.org/uniprot/E8V1Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS19685 ^@ http://purl.uniprot.org/uniprot/E8V2Z7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/401053:ACIPR4_RS18010 ^@ http://purl.uniprot.org/uniprot/E8UZM7 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/401053:ACIPR4_RS09360 ^@ http://purl.uniprot.org/uniprot/E8V5S7 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/401053:ACIPR4_RS16025 ^@ http://purl.uniprot.org/uniprot/E8V7K3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/401053:ACIPR4_RS13825 ^@ http://purl.uniprot.org/uniprot/E8V2S6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS09455 ^@ http://purl.uniprot.org/uniprot/E8V5U7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS10210 ^@ http://purl.uniprot.org/uniprot/E8V7E0 ^@ Function|||Similarity ^@ Belongs to the transposase IS30 family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/401053:ACIPR4_RS03180 ^@ http://purl.uniprot.org/uniprot/E8V4R9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS06545 ^@ http://purl.uniprot.org/uniprot/E8UZB3 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/401053:ACIPR4_RS19095 ^@ http://purl.uniprot.org/uniprot/E8V225 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/401053:ACIPR4_RS05440 ^@ http://purl.uniprot.org/uniprot/E8UX34 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/401053:ACIPR4_RS16090 ^@ http://purl.uniprot.org/uniprot/E8V808 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/401053:ACIPR4_RS10835 ^@ http://purl.uniprot.org/uniprot/E8V8J8 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/401053:ACIPR4_RS11750 ^@ http://purl.uniprot.org/uniprot/E8UYJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS02105 ^@ http://purl.uniprot.org/uniprot/E8V2C8 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/401053:ACIPR4_RS06265 ^@ http://purl.uniprot.org/uniprot/E8UZ61 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS04485 ^@ http://purl.uniprot.org/uniprot/E8V7N3 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/401053:ACIPR4_RS04170 ^@ http://purl.uniprot.org/uniprot/E8V726 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/401053:ACIPR4_RS04595 ^@ http://purl.uniprot.org/uniprot/E8V7Q4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS18750 ^@ http://purl.uniprot.org/uniprot/E8V198 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/401053:ACIPR4_RS08360 ^@ http://purl.uniprot.org/uniprot/E8V3D2 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/401053:ACIPR4_RS14765 ^@ http://purl.uniprot.org/uniprot/E8V542 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/401053:ACIPR4_RS09375 ^@ http://purl.uniprot.org/uniprot/E8V5T0 ^@ Similarity ^@ Belongs to the Lgt family. http://togogenome.org/gene/401053:ACIPR4_RS21235 ^@ http://purl.uniprot.org/uniprot/E8V6Y2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS06880 ^@ http://purl.uniprot.org/uniprot/E8V044 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/401053:ACIPR4_RS19445 ^@ http://purl.uniprot.org/uniprot/E8V2V1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS20580 ^@ http://purl.uniprot.org/uniprot/E8V5B4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS09005 ^@ http://purl.uniprot.org/uniprot/E8V4Y8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/401053:ACIPR4_RS03775 ^@ http://purl.uniprot.org/uniprot/E8V6C3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS16190 ^@ http://purl.uniprot.org/uniprot/E8V831 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/401053:ACIPR4_RS12705 ^@ http://purl.uniprot.org/uniprot/E8V0B2 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS12370 ^@ http://purl.uniprot.org/uniprot/E8UZI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS21050 ^@ http://purl.uniprot.org/uniprot/E8V677 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/401053:ACIPR4_RS07555 ^@ http://purl.uniprot.org/uniprot/E8V1Q3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/401053:ACIPR4_RS14085 ^@ http://purl.uniprot.org/uniprot/E8V3I8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/401053:ACIPR4_RS05665 ^@ http://purl.uniprot.org/uniprot/E8UXM0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS04360 ^@ http://purl.uniprot.org/uniprot/E8V766 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/401053:ACIPR4_RS15260 ^@ http://purl.uniprot.org/uniprot/E8V609 ^@ Similarity ^@ Belongs to the HisA/HisF family. http://togogenome.org/gene/401053:ACIPR4_RS17920 ^@ http://purl.uniprot.org/uniprot/E8UZK8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS13945 ^@ http://purl.uniprot.org/uniprot/E8V3G2 ^@ Similarity ^@ Belongs to the tannase family. http://togogenome.org/gene/401053:ACIPR4_RS04520 ^@ http://purl.uniprot.org/uniprot/E8V7P0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell inner membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS15465 ^@ http://purl.uniprot.org/uniprot/E8V6R9 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/401053:ACIPR4_RS10315 ^@ http://purl.uniprot.org/uniprot/E8V7V0 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/401053:ACIPR4_RS09680 ^@ http://purl.uniprot.org/uniprot/E8V6K9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS03335 ^@ http://purl.uniprot.org/uniprot/E8V5H0 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/401053:ACIPR4_RS10775 ^@ http://purl.uniprot.org/uniprot/E8V8I6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS19755 ^@ http://purl.uniprot.org/uniprot/E8V3M0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/401053:ACIPR4_RS09020 ^@ http://purl.uniprot.org/uniprot/E8V4Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS17025 ^@ http://purl.uniprot.org/uniprot/E8UXF8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/401053:ACIPR4_RS12910 ^@ http://purl.uniprot.org/uniprot/E8V123 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS15300 ^@ http://purl.uniprot.org/uniprot/E8V617 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/401053:ACIPR4_RS07400 ^@ http://purl.uniprot.org/uniprot/E8V1M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS08345 ^@ http://purl.uniprot.org/uniprot/E8V3C9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS13220 ^@ http://purl.uniprot.org/uniprot/E8V1U6 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/401053:ACIPR4_RS11930 ^@ http://purl.uniprot.org/uniprot/E8UYM9 ^@ Similarity ^@ Belongs to the TrbI/VirB10 family. http://togogenome.org/gene/401053:ACIPR4_RS19480 ^@ http://purl.uniprot.org/uniprot/E8V2V8 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS01275 ^@ http://purl.uniprot.org/uniprot/E8V0N7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Cdh family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS07840 ^@ http://purl.uniprot.org/uniprot/E8V2H4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS04195 ^@ http://purl.uniprot.org/uniprot/E8V731 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/401053:ACIPR4_RS10080 ^@ http://purl.uniprot.org/uniprot/E8V7B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS03625 ^@ http://purl.uniprot.org/uniprot/E8V5M5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS06565 ^@ http://purl.uniprot.org/uniprot/E8UZB7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/401053:ACIPR4_RS20605 ^@ http://purl.uniprot.org/uniprot/E8V5C1 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/401053:ACIPR4_RS20655 ^@ http://purl.uniprot.org/uniprot/E8V5D1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/401053:ACIPR4_RS02760 ^@ http://purl.uniprot.org/uniprot/E8V3X8 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/401053:ACIPR4_RS07940 ^@ http://purl.uniprot.org/uniprot/E8V2J3 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS13500 ^@ http://purl.uniprot.org/uniprot/E8V1Z9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/401053:ACIPR4_RS09330 ^@ http://purl.uniprot.org/uniprot/E8V5S1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS07675 ^@ http://purl.uniprot.org/uniprot/E8V1S9 ^@ Similarity ^@ Belongs to the class A bacterial acid phosphatase family. http://togogenome.org/gene/401053:ACIPR4_RS00890 ^@ http://purl.uniprot.org/uniprot/E8UZU4 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/401053:ACIPR4_RS12790 ^@ http://purl.uniprot.org/uniprot/E8V0C9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS18895 ^@ http://purl.uniprot.org/uniprot/E8V1C6 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/401053:ACIPR4_RS11700 ^@ http://purl.uniprot.org/uniprot/E8UYI5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/401053:ACIPR4_RS15055 ^@ http://purl.uniprot.org/uniprot/E8V5W9 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/401053:ACIPR4_RS17015 ^@ http://purl.uniprot.org/uniprot/E8UXF6 ^@ Similarity|||Subunit ^@ Belongs to the FPG family.|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS08690 ^@ http://purl.uniprot.org/uniprot/E8V464 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS04200 ^@ http://purl.uniprot.org/uniprot/E8V732 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS09055 ^@ http://purl.uniprot.org/uniprot/E8V4Z8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS14475 ^@ http://purl.uniprot.org/uniprot/E8V4C4 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS01320 ^@ http://purl.uniprot.org/uniprot/E8V0P7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS17670 ^@ http://purl.uniprot.org/uniprot/E8UYT5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS05495 ^@ http://purl.uniprot.org/uniprot/E8UXI7 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS20735 ^@ http://purl.uniprot.org/uniprot/E8V5E8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS15815 ^@ http://purl.uniprot.org/uniprot/E8V7G1 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS07455 ^@ http://purl.uniprot.org/uniprot/E8V1N4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS11220 ^@ http://purl.uniprot.org/uniprot/E8UX91 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/401053:ACIPR4_RS15800 ^@ http://purl.uniprot.org/uniprot/E8V7F8 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/401053:ACIPR4_RS09830 ^@ http://purl.uniprot.org/uniprot/E8V6N8 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/401053:ACIPR4_RS07565 ^@ http://purl.uniprot.org/uniprot/E8V1Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS04245 ^@ http://purl.uniprot.org/uniprot/E8V742 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS20530 ^@ http://purl.uniprot.org/uniprot/E8V5A3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS05105 ^@ http://purl.uniprot.org/uniprot/E8UWW8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/401053:ACIPR4_RS05915 ^@ http://purl.uniprot.org/uniprot/E8UYC7 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/401053:ACIPR4_RS13470 ^@ http://purl.uniprot.org/uniprot/E8V1Z3 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/401053:ACIPR4_RS04290 ^@ http://purl.uniprot.org/uniprot/E8V751 ^@ Similarity ^@ Belongs to the DapB family. http://togogenome.org/gene/401053:ACIPR4_RS09780 ^@ http://purl.uniprot.org/uniprot/E8V6M8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS09950 ^@ http://purl.uniprot.org/uniprot/E8V789 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS01825 ^@ http://purl.uniprot.org/uniprot/E8V272 ^@ Similarity ^@ In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/401053:ACIPR4_RS14995 ^@ http://purl.uniprot.org/uniprot/E8V5V7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/401053:ACIPR4_RS01795 ^@ http://purl.uniprot.org/uniprot/E8V1K4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS10225 ^@ http://purl.uniprot.org/uniprot/E8V7E3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS20110 ^@ http://purl.uniprot.org/uniprot/E8V4F3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnC family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/401053:ACIPR4_RS16360 ^@ http://purl.uniprot.org/uniprot/E8V864 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/401053:ACIPR4_RS13115 ^@ http://purl.uniprot.org/uniprot/E8V165 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS07805 ^@ http://purl.uniprot.org/uniprot/E8V2G7 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/401053:ACIPR4_RS17555 ^@ http://purl.uniprot.org/uniprot/E8UYR2 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/401053:ACIPR4_RS06460 ^@ http://purl.uniprot.org/uniprot/E8UZ96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS18410 ^@ http://purl.uniprot.org/uniprot/E8V0G4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/401053:ACIPR4_RS18640 ^@ http://purl.uniprot.org/uniprot/E8V178 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/401053:ACIPR4_RS08340 ^@ http://purl.uniprot.org/uniprot/E8V3C8 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/401053:ACIPR4_RS10450 ^@ http://purl.uniprot.org/uniprot/E8V7X6 ^@ Function|||Similarity ^@ Belongs to the PqqC family.|||Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ. http://togogenome.org/gene/401053:ACIPR4_RS14650 ^@ http://purl.uniprot.org/uniprot/E8V520 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS18800 ^@ http://purl.uniprot.org/uniprot/E8V1A8 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/401053:ACIPR4_RS12670 ^@ http://purl.uniprot.org/uniprot/E8V0A6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS05340 ^@ http://purl.uniprot.org/uniprot/E8UX14 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS21210 ^@ http://purl.uniprot.org/uniprot/E8V6X6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell inner membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/401053:ACIPR4_RS09050 ^@ http://purl.uniprot.org/uniprot/E8V4Z7 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/401053:ACIPR4_RS05090 ^@ http://purl.uniprot.org/uniprot/E8UWW5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS12035 ^@ http://purl.uniprot.org/uniprot/E8UYQ0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/401053:ACIPR4_RS19880 ^@ http://purl.uniprot.org/uniprot/E8V3P5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/401053:ACIPR4_RS12765 ^@ http://purl.uniprot.org/uniprot/E8V0C4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/401053:ACIPR4_RS04865 ^@ http://purl.uniprot.org/uniprot/E8V8A4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/401053:ACIPR4_RS17605 ^@ http://purl.uniprot.org/uniprot/E8UYS2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS18295 ^@ http://purl.uniprot.org/uniprot/E8V0E3 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/401053:ACIPR4_RS12620 ^@ http://purl.uniprot.org/uniprot/E8V096 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS15645 ^@ http://purl.uniprot.org/uniprot/E8V6V6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/401053:ACIPR4_RS05550 ^@ http://purl.uniprot.org/uniprot/E8UXJ7 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/401053:ACIPR4_RS14950 ^@ http://purl.uniprot.org/uniprot/E8V579 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/401053:ACIPR4_RS12425 ^@ http://purl.uniprot.org/uniprot/E8UZJ8 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/401053:ACIPR4_RS03955 ^@ http://purl.uniprot.org/uniprot/E8V6F8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS16045 ^@ http://purl.uniprot.org/uniprot/E8V7K7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/401053:ACIPR4_RS08655 ^@ http://purl.uniprot.org/uniprot/E8V457 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS19320 ^@ http://purl.uniprot.org/uniprot/E8V268 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/401053:ACIPR4_RS15155 ^@ http://purl.uniprot.org/uniprot/E8V5Y9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/401053:ACIPR4_RS17695 ^@ http://purl.uniprot.org/uniprot/E8UYT9 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit. http://togogenome.org/gene/401053:ACIPR4_RS04315 ^@ http://purl.uniprot.org/uniprot/E8V756 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/401053:ACIPR4_RS06575 ^@ http://purl.uniprot.org/uniprot/E8UZB9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS09940 ^@ http://purl.uniprot.org/uniprot/E8V787 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/401053:ACIPR4_RS02050 ^@ http://purl.uniprot.org/uniprot/E8V2B7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/401053:ACIPR4_RS00660 ^@ http://purl.uniprot.org/uniprot/E8UZ32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS14740 ^@ http://purl.uniprot.org/uniprot/E8V537 ^@ Similarity ^@ Belongs to the glycosyltransferase 2 family. http://togogenome.org/gene/401053:ACIPR4_RS04125 ^@ http://purl.uniprot.org/uniprot/E8V717 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS14800 ^@ http://purl.uniprot.org/uniprot/E8V549 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS12155 ^@ http://purl.uniprot.org/uniprot/E8UZE6 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/401053:ACIPR4_RS13555 ^@ http://purl.uniprot.org/uniprot/E8V2M3 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS20950 ^@ http://purl.uniprot.org/uniprot/E8V658 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS16080 ^@ http://purl.uniprot.org/uniprot/E8V806 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/401053:ACIPR4_RS14725 ^@ http://purl.uniprot.org/uniprot/E8V534 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS07255 ^@ http://purl.uniprot.org/uniprot/E8V0Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS03490 ^@ http://purl.uniprot.org/uniprot/E8V5K0 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/401053:ACIPR4_RS07820 ^@ http://purl.uniprot.org/uniprot/E8V2H0 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS07735 ^@ http://purl.uniprot.org/uniprot/E8V2F3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS06260 ^@ http://purl.uniprot.org/uniprot/E8UZ60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS02010 ^@ http://purl.uniprot.org/uniprot/E8V2A9 ^@ Function|||Similarity ^@ Belongs to the UxaE family.|||Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA). http://togogenome.org/gene/401053:ACIPR4_RS09210 ^@ http://purl.uniprot.org/uniprot/E8V5P8 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/401053:ACIPR4_RS01180 ^@ http://purl.uniprot.org/uniprot/E8V0L8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS12855 ^@ http://purl.uniprot.org/uniprot/E8V112 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS04400 ^@ http://purl.uniprot.org/uniprot/E8V7L6 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS05795 ^@ http://purl.uniprot.org/uniprot/E8UXP6 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS20165 ^@ http://purl.uniprot.org/uniprot/E8V4G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS16040 ^@ http://purl.uniprot.org/uniprot/E8V7K6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/401053:ACIPR4_RS16210 ^@ http://purl.uniprot.org/uniprot/E8V835 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/401053:ACIPR4_RS04090 ^@ http://purl.uniprot.org/uniprot/E8V710 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/401053:ACIPR4_RS02560 ^@ http://purl.uniprot.org/uniprot/E8V3T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial glucokinase family.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS16235 ^@ http://purl.uniprot.org/uniprot/E8V840 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS21695 ^@ http://purl.uniprot.org/uniprot/E8V0B5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/401053:ACIPR4_RS02670 ^@ http://purl.uniprot.org/uniprot/E8V3W0 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/401053:ACIPR4_RS06500 ^@ http://purl.uniprot.org/uniprot/E8UZA4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/401053:ACIPR4_RS01040 ^@ http://purl.uniprot.org/uniprot/E8UZX5 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS17105 ^@ http://purl.uniprot.org/uniprot/E8UXH2 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/401053:ACIPR4_RS06380 ^@ http://purl.uniprot.org/uniprot/E8UZ81 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/401053:ACIPR4_RS20480 ^@ http://purl.uniprot.org/uniprot/E8V593 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/401053:ACIPR4_RS20980 ^@ http://purl.uniprot.org/uniprot/E8V664 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/401053:ACIPR4_RS09000 ^@ http://purl.uniprot.org/uniprot/E8V4Y7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/401053:ACIPR4_RS09250 ^@ http://purl.uniprot.org/uniprot/E8V5Q6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS15640 ^@ http://purl.uniprot.org/uniprot/E8V6V5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/401053:ACIPR4_RS18125 ^@ http://purl.uniprot.org/uniprot/E8UZP8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/401053:ACIPR4_RS06900 ^@ http://purl.uniprot.org/uniprot/E8V048 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/401053:ACIPR4_RS03350 ^@ http://purl.uniprot.org/uniprot/E8V5H3 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/401053:ACIPR4_RS20025 ^@ http://purl.uniprot.org/uniprot/E8V3S4 ^@ Similarity ^@ Belongs to the glucose-6-phosphate 1-epimerase family. http://togogenome.org/gene/401053:ACIPR4_RS18550 ^@ http://purl.uniprot.org/uniprot/E8V0J2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/401053:ACIPR4_RS16680 ^@ http://purl.uniprot.org/uniprot/E8V8S4 ^@ Function|||Subcellular Location Annotation ^@ Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.|||Cell inner membrane http://togogenome.org/gene/401053:ACIPR4_RS04570 ^@ http://purl.uniprot.org/uniprot/E8V7Q0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS18940 ^@ http://purl.uniprot.org/uniprot/E8V1D5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS15320 ^@ http://purl.uniprot.org/uniprot/E8V622 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/401053:ACIPR4_RS18930 ^@ http://purl.uniprot.org/uniprot/E8V1D3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/401053:ACIPR4_RS16120 ^@ http://purl.uniprot.org/uniprot/E8V814 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/401053:ACIPR4_RS11895 ^@ http://purl.uniprot.org/uniprot/E8UYM2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS08305 ^@ http://purl.uniprot.org/uniprot/E8V3C1 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/401053:ACIPR4_RS04920 ^@ http://purl.uniprot.org/uniprot/E8V8B7 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/401053:ACIPR4_RS04015 ^@ http://purl.uniprot.org/uniprot/E8V6H0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS11095 ^@ http://purl.uniprot.org/uniprot/E8UX66 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS14230 ^@ http://purl.uniprot.org/uniprot/E8V479 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS11135 ^@ http://purl.uniprot.org/uniprot/E8UX74 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS20200 ^@ http://purl.uniprot.org/uniprot/E8V4H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS21160 ^@ http://purl.uniprot.org/uniprot/E8V6W6 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/401053:ACIPR4_RS10320 ^@ http://purl.uniprot.org/uniprot/E8V7V1 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/401053:ACIPR4_RS02130 ^@ http://purl.uniprot.org/uniprot/E8V2D3 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/401053:ACIPR4_RS05600 ^@ http://purl.uniprot.org/uniprot/E8UXK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/401053:ACIPR4_RS02515 ^@ http://purl.uniprot.org/uniprot/E8V367 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/401053:ACIPR4_RS17055 ^@ http://purl.uniprot.org/uniprot/E8UXG4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/401053:ACIPR4_RS11880 ^@ http://purl.uniprot.org/uniprot/E8UYL9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/401053:ACIPR4_RS05780 ^@ http://purl.uniprot.org/uniprot/E8UXP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS05655 ^@ http://purl.uniprot.org/uniprot/E8UXL8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/401053:ACIPR4_RS04240 ^@ http://purl.uniprot.org/uniprot/E8V741 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/401053:ACIPR4_RS16915 ^@ http://purl.uniprot.org/uniprot/E8UXD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS17445 ^@ http://purl.uniprot.org/uniprot/E8UY24 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/401053:ACIPR4_RS10820 ^@ http://purl.uniprot.org/uniprot/E8V8J5 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/401053:ACIPR4_RS12355 ^@ http://purl.uniprot.org/uniprot/E8UZI4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/401053:ACIPR4_RS05770 ^@ http://purl.uniprot.org/uniprot/E8UXP1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/401053:ACIPR4_RS09075 ^@ http://purl.uniprot.org/uniprot/E8V502 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliQ/MopD/SpaQ family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS19715 ^@ http://purl.uniprot.org/uniprot/E8V302 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/401053:ACIPR4_RS21185 ^@ http://purl.uniprot.org/uniprot/E8V6X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/401053:ACIPR4_RS05320 ^@ http://purl.uniprot.org/uniprot/E8UX10 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/401053:ACIPR4_RS21670 ^@ http://purl.uniprot.org/uniprot/E8UZF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS13230 ^@ http://purl.uniprot.org/uniprot/E8V1U7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/401053:ACIPR4_RS16535 ^@ http://purl.uniprot.org/uniprot/E8V8P4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/401053:ACIPR4_RS18855 ^@ http://purl.uniprot.org/uniprot/E8V1B8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III. http://togogenome.org/gene/401053:ACIPR4_RS10310 ^@ http://purl.uniprot.org/uniprot/E8V7U9 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/401053:ACIPR4_RS19055 ^@ http://purl.uniprot.org/uniprot/E8V216 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/401053:ACIPR4_RS08925 ^@ http://purl.uniprot.org/uniprot/E8V4X2 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/401053:ACIPR4_RS06140 ^@ http://purl.uniprot.org/uniprot/E8UYG6 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/401053:ACIPR4_RS05515 ^@ http://purl.uniprot.org/uniprot/E8UXJ0 ^@ Function|||Similarity ^@ Belongs to the anhydro-N-acetylmuramic acid kinase family.|||Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/401053:ACIPR4_RS09115 ^@ http://purl.uniprot.org/uniprot/E8V510 ^@ Similarity|||Subunit ^@ Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/401053:ACIPR4_RS05660 ^@ http://purl.uniprot.org/uniprot/E8UXL9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/401053:ACIPR4_RS05555 ^@ http://purl.uniprot.org/uniprot/E8UXJ8 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/401053:ACIPR4_RS05620 ^@ http://purl.uniprot.org/uniprot/E8UXL1 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/401053:ACIPR4_RS02420 ^@ http://purl.uniprot.org/uniprot/E8V348 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/401053:ACIPR4_RS19835 ^@ http://purl.uniprot.org/uniprot/E8V3N6 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/401053:ACIPR4_RS21285 ^@ http://purl.uniprot.org/uniprot/E8V6Z3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS05750 ^@ http://purl.uniprot.org/uniprot/E8UXN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS15935 ^@ http://purl.uniprot.org/uniprot/E8V7I5 ^@ Similarity ^@ Belongs to the DAMOX/DASOX family. http://togogenome.org/gene/401053:ACIPR4_RS02855 ^@ http://purl.uniprot.org/uniprot/E8V3Z6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS03275 ^@ http://purl.uniprot.org/uniprot/E8V4T8 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS21255 ^@ http://purl.uniprot.org/uniprot/E8V6Y7 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS05670 ^@ http://purl.uniprot.org/uniprot/E8UXM1 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/401053:ACIPR4_RS09345 ^@ http://purl.uniprot.org/uniprot/E8V5S4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS20695 ^@ http://purl.uniprot.org/uniprot/E8V5E0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/401053:ACIPR4_RS20115 ^@ http://purl.uniprot.org/uniprot/E8V4F4 ^@ Caution|||Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS14365 ^@ http://purl.uniprot.org/uniprot/E8V4A4 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/401053:ACIPR4_RS20710 ^@ http://purl.uniprot.org/uniprot/E8V5E3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS10300 ^@ http://purl.uniprot.org/uniprot/E8V7U7 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/401053:ACIPR4_RS15170 ^@ http://purl.uniprot.org/uniprot/E8V5Z1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS06495 ^@ http://purl.uniprot.org/uniprot/E8UZA3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/401053:ACIPR4_RS16250 ^@ http://purl.uniprot.org/uniprot/E8V843 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/401053:ACIPR4_RS10725 ^@ http://purl.uniprot.org/uniprot/E8V8H6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/401053:ACIPR4_RS12830 ^@ http://purl.uniprot.org/uniprot/E8V107 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/401053:ACIPR4_RS20565 ^@ http://purl.uniprot.org/uniprot/E8V5B1 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/401053:ACIPR4_RS17305 ^@ http://purl.uniprot.org/uniprot/E8UXZ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homotetramer. http://togogenome.org/gene/401053:ACIPR4_RS02595 ^@ http://purl.uniprot.org/uniprot/E8V3U5 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/401053:ACIPR4_RS13715 ^@ http://purl.uniprot.org/uniprot/E8V2Q5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/401053:ACIPR4_RS14900 ^@ http://purl.uniprot.org/uniprot/E8V569 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS17125 ^@ http://purl.uniprot.org/uniprot/E8UXH5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/401053:ACIPR4_RS07070 ^@ http://purl.uniprot.org/uniprot/E8V0U8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS04615 ^@ http://purl.uniprot.org/uniprot/E8V7Q8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/401053:ACIPR4_RS03345 ^@ http://purl.uniprot.org/uniprot/E8V5H2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS19420 ^@ http://purl.uniprot.org/uniprot/E8V2U6 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS10250 ^@ http://purl.uniprot.org/uniprot/E8V7T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS07235 ^@ http://purl.uniprot.org/uniprot/E8V0Y2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS16225 ^@ http://purl.uniprot.org/uniprot/E8V838 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/401053:ACIPR4_RS07250 ^@ http://purl.uniprot.org/uniprot/E8V0Y5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS00365 ^@ http://purl.uniprot.org/uniprot/E8UYA3 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/401053:ACIPR4_RS00640 ^@ http://purl.uniprot.org/uniprot/E8UZ28 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/401053:ACIPR4_RS10085 ^@ http://purl.uniprot.org/uniprot/E8V7B6 ^@ Caution|||Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS01990 ^@ http://purl.uniprot.org/uniprot/E8V2A5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/401053:ACIPR4_RS14795 ^@ http://purl.uniprot.org/uniprot/E8V548 ^@ Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/401053:ACIPR4_RS15885 ^@ http://purl.uniprot.org/uniprot/E8V7H6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/401053:ACIPR4_RS09220 ^@ http://purl.uniprot.org/uniprot/E8V5Q0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS09015 ^@ http://purl.uniprot.org/uniprot/E8V4Z0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/401053:ACIPR4_RS09190 ^@ http://purl.uniprot.org/uniprot/E8V5P4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/401053:ACIPR4_RS14025 ^@ http://purl.uniprot.org/uniprot/E8V3H8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS15785 ^@ http://purl.uniprot.org/uniprot/E8V7F5 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS02510 ^@ http://purl.uniprot.org/uniprot/E8V366 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS13235 ^@ http://purl.uniprot.org/uniprot/E8V1U8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 42 family. http://togogenome.org/gene/401053:ACIPR4_RS06570 ^@ http://purl.uniprot.org/uniprot/E8UZB8 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/401053:ACIPR4_RS02245 ^@ http://purl.uniprot.org/uniprot/E8V313 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/401053:ACIPR4_RS13935 ^@ http://purl.uniprot.org/uniprot/E8V3G0 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/401053:ACIPR4_RS02555 ^@ http://purl.uniprot.org/uniprot/E8V3T7 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/401053:ACIPR4_RS08975 ^@ http://purl.uniprot.org/uniprot/E8V4Y2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS05840 ^@ http://purl.uniprot.org/uniprot/E8UYB2 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/401053:ACIPR4_RS09875 ^@ http://purl.uniprot.org/uniprot/E8V773 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/401053:ACIPR4_RS02180 ^@ http://purl.uniprot.org/uniprot/E8V2E2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS12050 ^@ http://purl.uniprot.org/uniprot/E8UYQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS20125 ^@ http://purl.uniprot.org/uniprot/E8V4F6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/401053:ACIPR4_RS20310 ^@ http://purl.uniprot.org/uniprot/E8V4J3 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/401053:ACIPR4_RS11310 ^@ http://purl.uniprot.org/uniprot/E8UXQ7 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/401053:ACIPR4_RS18980 ^@ http://purl.uniprot.org/uniprot/E8V201 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/401053:ACIPR4_RS21200 ^@ http://purl.uniprot.org/uniprot/E8V6X4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 3 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS10555 ^@ http://purl.uniprot.org/uniprot/E8V7Z7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS02890 ^@ http://purl.uniprot.org/uniprot/E8V403 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS15665 ^@ http://purl.uniprot.org/uniprot/E8V6W0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS18380 ^@ http://purl.uniprot.org/uniprot/E8V0F9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS18755 ^@ http://purl.uniprot.org/uniprot/E8V199 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS00400 ^@ http://purl.uniprot.org/uniprot/E8UYB0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS02325 ^@ http://purl.uniprot.org/uniprot/E8V329 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/401053:ACIPR4_RS08590 ^@ http://purl.uniprot.org/uniprot/E8V444 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS09080 ^@ http://purl.uniprot.org/uniprot/E8V503 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliR/MopE/SpaR family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS16150 ^@ http://purl.uniprot.org/uniprot/E8V821 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/401053:ACIPR4_RS14825 ^@ http://purl.uniprot.org/uniprot/E8V554 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase S45 family.|||Binds 1 Ca(2+) ion per dimer. http://togogenome.org/gene/401053:ACIPR4_RS08785 ^@ http://purl.uniprot.org/uniprot/E8V4U4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS19855 ^@ http://purl.uniprot.org/uniprot/E8V3P0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS11140 ^@ http://purl.uniprot.org/uniprot/E8UX75 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/401053:ACIPR4_RS15045 ^@ http://purl.uniprot.org/uniprot/E8V5W7 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/401053:ACIPR4_RS16260 ^@ http://purl.uniprot.org/uniprot/E8V845 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS16850 ^@ http://purl.uniprot.org/uniprot/E8UXC0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS19240 ^@ http://purl.uniprot.org/uniprot/E8V252 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS08265 ^@ http://purl.uniprot.org/uniprot/E8V3B3 ^@ Similarity ^@ Belongs to the malate synthase family. http://togogenome.org/gene/401053:ACIPR4_RS20830 ^@ http://purl.uniprot.org/uniprot/E8V635 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum|||Golgi apparatus|||Lysosome http://togogenome.org/gene/401053:ACIPR4_RS06745 ^@ http://purl.uniprot.org/uniprot/E8V017 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/401053:ACIPR4_RS08280 ^@ http://purl.uniprot.org/uniprot/E8V3B6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MsrQ family.|||Binds 1 FMN per subunit.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Cell inner membrane|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain. http://togogenome.org/gene/401053:ACIPR4_RS04080 ^@ http://purl.uniprot.org/uniprot/E8V708 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS20145 ^@ http://purl.uniprot.org/uniprot/E8V4G0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell inner membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/401053:ACIPR4_RS04575 ^@ http://purl.uniprot.org/uniprot/E8V7Q1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS03020 ^@ http://purl.uniprot.org/uniprot/E8V4N8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS05900 ^@ http://purl.uniprot.org/uniprot/E8UYC4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS02475 ^@ http://purl.uniprot.org/uniprot/E8V359 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS04165 ^@ http://purl.uniprot.org/uniprot/E8V725 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS00905 ^@ http://purl.uniprot.org/uniprot/E8UZU7 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum|||Golgi apparatus|||Lysosome http://togogenome.org/gene/401053:ACIPR4_RS02960 ^@ http://purl.uniprot.org/uniprot/E8V4M6 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/401053:ACIPR4_RS02535 ^@ http://purl.uniprot.org/uniprot/E8V372 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/401053:ACIPR4_RS17315 ^@ http://purl.uniprot.org/uniprot/E8UXZ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/401053:ACIPR4_RS18920 ^@ http://purl.uniprot.org/uniprot/E8V1D1 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/401053:ACIPR4_RS02990 ^@ http://purl.uniprot.org/uniprot/E8V4N2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/401053:ACIPR4_RS03025 ^@ http://purl.uniprot.org/uniprot/E8V4N9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS15040 ^@ http://purl.uniprot.org/uniprot/E8V5W6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/401053:ACIPR4_RS02410 ^@ http://purl.uniprot.org/uniprot/E8V346 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/401053:ACIPR4_RS10000 ^@ http://purl.uniprot.org/uniprot/E8V799 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS03270 ^@ http://purl.uniprot.org/uniprot/E8V4T7 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/401053:ACIPR4_RS11050 ^@ http://purl.uniprot.org/uniprot/E8UX57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS19010 ^@ http://purl.uniprot.org/uniprot/E8V207 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/401053:ACIPR4_RS02985 ^@ http://purl.uniprot.org/uniprot/E8V4N1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/401053:ACIPR4_RS00785 ^@ http://purl.uniprot.org/uniprot/E8UZS4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/401053:ACIPR4_RS17830 ^@ http://purl.uniprot.org/uniprot/E8UYW7 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS08275 ^@ http://purl.uniprot.org/uniprot/E8V3B5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MsrP family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.|||Periplasm http://togogenome.org/gene/401053:ACIPR4_RS09985 ^@ http://purl.uniprot.org/uniprot/E8V796 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/401053:ACIPR4_RS07475 ^@ http://purl.uniprot.org/uniprot/E8V1N8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS19680 ^@ http://purl.uniprot.org/uniprot/E8V2Z6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/401053:ACIPR4_RS15605 ^@ http://purl.uniprot.org/uniprot/E8V6U8 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/401053:ACIPR4_RS03000 ^@ http://purl.uniprot.org/uniprot/E8V4N4 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/401053:ACIPR4_RS09110 ^@ http://purl.uniprot.org/uniprot/E8V509 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/401053:ACIPR4_RS16005 ^@ http://purl.uniprot.org/uniprot/E8V7J9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/401053:ACIPR4_RS00995 ^@ http://purl.uniprot.org/uniprot/E8UZW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS13145 ^@ http://purl.uniprot.org/uniprot/E8V171 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily. http://togogenome.org/gene/401053:ACIPR4_RS03835 ^@ http://purl.uniprot.org/uniprot/E8V6D5 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/401053:ACIPR4_RS20765 ^@ http://purl.uniprot.org/uniprot/E8V5F3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/401053:ACIPR4_RS21045 ^@ http://purl.uniprot.org/uniprot/E8V676 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS06735 ^@ http://purl.uniprot.org/uniprot/E8V016 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS11465 ^@ http://purl.uniprot.org/uniprot/E8UXT1 ^@ Similarity ^@ Belongs to the neutral ceramidase family. http://togogenome.org/gene/401053:ACIPR4_RS08850 ^@ http://purl.uniprot.org/uniprot/E8V4V7 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS07365 ^@ http://purl.uniprot.org/uniprot/E8V1L6 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/401053:ACIPR4_RS06970 ^@ http://purl.uniprot.org/uniprot/E8V0S7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 8 (cellulase D) family. http://togogenome.org/gene/401053:ACIPR4_RS14260 ^@ http://purl.uniprot.org/uniprot/E8V486 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS00860 ^@ http://purl.uniprot.org/uniprot/E8UZT8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutB family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/401053:ACIPR4_RS14885 ^@ http://purl.uniprot.org/uniprot/E8V566 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/401053:ACIPR4_RS13705 ^@ http://purl.uniprot.org/uniprot/E8V2Q3 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS02720 ^@ http://purl.uniprot.org/uniprot/E8V3X0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/401053:ACIPR4_RS01055 ^@ http://purl.uniprot.org/uniprot/E8UZX8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/401053:ACIPR4_RS16545 ^@ http://purl.uniprot.org/uniprot/E8V8P6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/401053:ACIPR4_RS15840 ^@ http://purl.uniprot.org/uniprot/E8V7G6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS02570 ^@ http://purl.uniprot.org/uniprot/E8V3U0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS03965 ^@ http://purl.uniprot.org/uniprot/E8V6G0 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/401053:ACIPR4_RS10695 ^@ http://purl.uniprot.org/uniprot/E8V8H0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/401053:ACIPR4_RS20150 ^@ http://purl.uniprot.org/uniprot/E8V4G1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell inner membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/401053:ACIPR4_RS01410 ^@ http://purl.uniprot.org/uniprot/E8V0R5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS16110 ^@ http://purl.uniprot.org/uniprot/E8UXH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/401053:ACIPR4_RS08180 ^@ http://purl.uniprot.org/uniprot/E8V3A0 ^@ Function|||Similarity ^@ Belongs to the threonine aldolase family.|||Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. http://togogenome.org/gene/401053:ACIPR4_RS18955 ^@ http://purl.uniprot.org/uniprot/E8V1D8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/401053:ACIPR4_RS10995 ^@ http://purl.uniprot.org/uniprot/E8UX46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS12930 ^@ http://purl.uniprot.org/uniprot/E8V127 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS01060 ^@ http://purl.uniprot.org/uniprot/E8UZX9 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS06290 ^@ http://purl.uniprot.org/uniprot/E8UZ66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/401053:ACIPR4_RS10755 ^@ http://purl.uniprot.org/uniprot/E8V8I2 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/401053:ACIPR4_RS14940 ^@ http://purl.uniprot.org/uniprot/E8V577 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/401053:ACIPR4_RS02530 ^@ http://purl.uniprot.org/uniprot/E8V371 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/401053:ACIPR4_RS03465 ^@ http://purl.uniprot.org/uniprot/E8V5J5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS02040 ^@ http://purl.uniprot.org/uniprot/E8V2B5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/401053:ACIPR4_RS16065 ^@ http://purl.uniprot.org/uniprot/E8V7L1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/401053:ACIPR4_RS18885 ^@ http://purl.uniprot.org/uniprot/E8V1C4 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS16780 ^@ http://purl.uniprot.org/uniprot/E8V8U3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/401053:ACIPR4_RS02470 ^@ http://purl.uniprot.org/uniprot/E8V358 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/401053:ACIPR4_RS09775 ^@ http://purl.uniprot.org/uniprot/E8V6M7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS05645 ^@ http://purl.uniprot.org/uniprot/E8UXL6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS05200 ^@ http://purl.uniprot.org/uniprot/E8UWY6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS17295 ^@ http://purl.uniprot.org/uniprot/E8UXZ4 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS13045 ^@ http://purl.uniprot.org/uniprot/E8V152 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. http://togogenome.org/gene/401053:ACIPR4_RS13520 ^@ http://purl.uniprot.org/uniprot/E8V2L6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/401053:ACIPR4_RS03225 ^@ http://purl.uniprot.org/uniprot/E8V4S8 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/401053:ACIPR4_RS16585 ^@ http://purl.uniprot.org/uniprot/E8V8Q4 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/401053:ACIPR4_RS06550 ^@ http://purl.uniprot.org/uniprot/E8UZB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/401053:ACIPR4_RS09410 ^@ http://purl.uniprot.org/uniprot/E8V5T7 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS17885 ^@ http://purl.uniprot.org/uniprot/E8UZK1 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/401053:ACIPR4_RS02185 ^@ http://purl.uniprot.org/uniprot/E8V2E3 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/401053:ACIPR4_RS17700 ^@ http://purl.uniprot.org/uniprot/E8UYU0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS19510 ^@ http://purl.uniprot.org/uniprot/E8V2W4 ^@ Similarity ^@ Belongs to the UPF0502 family. http://togogenome.org/gene/401053:ACIPR4_RS12255 ^@ http://purl.uniprot.org/uniprot/E8UZG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS12640 ^@ http://purl.uniprot.org/uniprot/E8V0A0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS17630 ^@ http://purl.uniprot.org/uniprot/E8UYS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS08450 ^@ http://purl.uniprot.org/uniprot/E8V416 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 27 family. http://togogenome.org/gene/401053:ACIPR4_RS09285 ^@ http://purl.uniprot.org/uniprot/E8V5R3 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/401053:ACIPR4_RS01895 ^@ http://purl.uniprot.org/uniprot/E8V286 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/401053:ACIPR4_RS20485 ^@ http://purl.uniprot.org/uniprot/E8V594 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/401053:ACIPR4_RS16430 ^@ http://purl.uniprot.org/uniprot/E8V876 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS09960 ^@ http://purl.uniprot.org/uniprot/E8V791 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TolB family.|||Periplasm http://togogenome.org/gene/401053:ACIPR4_RS04940 ^@ http://purl.uniprot.org/uniprot/E8V8C1 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/401053:ACIPR4_RS02995 ^@ http://purl.uniprot.org/uniprot/E8V4N3 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/401053:ACIPR4_RS09890 ^@ http://purl.uniprot.org/uniprot/E8V776 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS12950 ^@ http://purl.uniprot.org/uniprot/E8V131 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS17340 ^@ http://purl.uniprot.org/uniprot/E8UY03 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS02750 ^@ http://purl.uniprot.org/uniprot/E8V3X6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS16775 ^@ http://purl.uniprot.org/uniprot/E8V8U2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS06560 ^@ http://purl.uniprot.org/uniprot/E8UZB6 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/401053:ACIPR4_RS04280 ^@ http://purl.uniprot.org/uniprot/E8V749 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/401053:ACIPR4_RS07490 ^@ http://purl.uniprot.org/uniprot/E8V1P1 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/401053:ACIPR4_RS15755 ^@ http://purl.uniprot.org/uniprot/E8V7E9 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS02205 ^@ http://purl.uniprot.org/uniprot/E8V305 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS09140 ^@ http://purl.uniprot.org/uniprot/E8V5N4 ^@ Similarity ^@ Belongs to the FlgM family. http://togogenome.org/gene/401053:ACIPR4_RS02765 ^@ http://purl.uniprot.org/uniprot/E8V3X9 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/401053:ACIPR4_RS19965 ^@ http://purl.uniprot.org/uniprot/E8V3R2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS20370 ^@ http://purl.uniprot.org/uniprot/E8V4K6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/401053:ACIPR4_RS14050 ^@ http://purl.uniprot.org/uniprot/E8V3I3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS01920 ^@ http://purl.uniprot.org/uniprot/E8V291 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/401053:ACIPR4_RS13955 ^@ http://purl.uniprot.org/uniprot/E8V3G4 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/401053:ACIPR4_RS11755 ^@ http://purl.uniprot.org/uniprot/E8UYJ5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS06470 ^@ http://purl.uniprot.org/uniprot/E8UZ98 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS12000 ^@ http://purl.uniprot.org/uniprot/E8UYP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS03705 ^@ http://purl.uniprot.org/uniprot/E8V6A9 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS10915 ^@ http://purl.uniprot.org/uniprot/E8V8L4 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family. http://togogenome.org/gene/401053:ACIPR4_RS01395 ^@ http://purl.uniprot.org/uniprot/E8V0R2 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS13565 ^@ http://purl.uniprot.org/uniprot/E8V2M5 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS19780 ^@ http://purl.uniprot.org/uniprot/E8V3M5 ^@ Similarity ^@ Belongs to the ATP-dependent DNA ligase family. http://togogenome.org/gene/401053:ACIPR4_RS06075 ^@ http://purl.uniprot.org/uniprot/E8UYF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS15795 ^@ http://purl.uniprot.org/uniprot/E8V7F7 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/401053:ACIPR4_RS01740 ^@ http://purl.uniprot.org/uniprot/E8V1J3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS16645 ^@ http://purl.uniprot.org/uniprot/E8V8R6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/401053:ACIPR4_RS02920 ^@ http://purl.uniprot.org/uniprot/E8V409 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS17130 ^@ http://purl.uniprot.org/uniprot/E8UXH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/401053:ACIPR4_RS14360 ^@ http://purl.uniprot.org/uniprot/E8V4A3 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/401053:ACIPR4_RS03995 ^@ http://purl.uniprot.org/uniprot/E8V6G6 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/401053:ACIPR4_RS18845 ^@ http://purl.uniprot.org/uniprot/E8V1B6 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/401053:ACIPR4_RS10155 ^@ http://purl.uniprot.org/uniprot/E8V7C9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/401053:ACIPR4_RS08935 ^@ http://purl.uniprot.org/uniprot/E8V4X4 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/401053:ACIPR4_RS05630 ^@ http://purl.uniprot.org/uniprot/E8UXL3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS06400 ^@ http://purl.uniprot.org/uniprot/E8UZ85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gas vesicle GvpF/GvpL family.|||Gas vesicle|||Vesicle http://togogenome.org/gene/401053:ACIPR4_RS03475 ^@ http://purl.uniprot.org/uniprot/E8V5J7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/401053:ACIPR4_RS04875 ^@ http://purl.uniprot.org/uniprot/E8V8A6 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/401053:ACIPR4_RS07495 ^@ http://purl.uniprot.org/uniprot/E8V1P2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS00875 ^@ http://purl.uniprot.org/uniprot/E8UZU1 ^@ Similarity ^@ Belongs to the bacterial phospholipase C family. http://togogenome.org/gene/401053:ACIPR4_RS16050 ^@ http://purl.uniprot.org/uniprot/E8V7K8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/401053:ACIPR4_RS12350 ^@ http://purl.uniprot.org/uniprot/E8UZI3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell inner membrane|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/401053:ACIPR4_RS05910 ^@ http://purl.uniprot.org/uniprot/E8UYC6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/401053:ACIPR4_RS07745 ^@ http://purl.uniprot.org/uniprot/E8V2F5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/401053:ACIPR4_RS08505 ^@ http://purl.uniprot.org/uniprot/E8V427 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS21145 ^@ http://purl.uniprot.org/uniprot/E8V696 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS06555 ^@ http://purl.uniprot.org/uniprot/E8UZB5 ^@ Similarity ^@ Belongs to the RNA polymerase subunit omega family. http://togogenome.org/gene/401053:ACIPR4_RS13480 ^@ http://purl.uniprot.org/uniprot/E8V1Z5 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/401053:ACIPR4_RS02660 ^@ http://purl.uniprot.org/uniprot/E8V3V8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/401053:ACIPR4_RS13315 ^@ http://purl.uniprot.org/uniprot/E8V1W4 ^@ Caution|||Similarity ^@ Belongs to the peptidase S8 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS15145 ^@ http://purl.uniprot.org/uniprot/E8V5Y7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS08420 ^@ http://purl.uniprot.org/uniprot/E8V410 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the KduI family.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. http://togogenome.org/gene/401053:ACIPR4_RS13560 ^@ http://purl.uniprot.org/uniprot/E8V2M4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase. http://togogenome.org/gene/401053:ACIPR4_RS08120 ^@ http://purl.uniprot.org/uniprot/E8V389 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/401053:ACIPR4_RS20360 ^@ http://purl.uniprot.org/uniprot/E8V4K4 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/401053:ACIPR4_RS03690 ^@ http://purl.uniprot.org/uniprot/E8V6A7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS13275 ^@ http://purl.uniprot.org/uniprot/E8V1V6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS10025 ^@ http://purl.uniprot.org/uniprot/E8V7A4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS08365 ^@ http://purl.uniprot.org/uniprot/E8V3D3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/401053:ACIPR4_RS12190 ^@ http://purl.uniprot.org/uniprot/E8UZF2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/401053:ACIPR4_RS06715 ^@ http://purl.uniprot.org/uniprot/E8V012 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS14645 ^@ http://purl.uniprot.org/uniprot/E8V519 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/401053:ACIPR4_RS15490 ^@ http://purl.uniprot.org/uniprot/E8V6S5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS14915 ^@ http://purl.uniprot.org/uniprot/E8V572 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS13105 ^@ http://purl.uniprot.org/uniprot/E8V163 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS15230 ^@ http://purl.uniprot.org/uniprot/E8V603 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/401053:ACIPR4_RS15070 ^@ http://purl.uniprot.org/uniprot/E8V5X3 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/401053:ACIPR4_RS18345 ^@ http://purl.uniprot.org/uniprot/E8V0F3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/401053:ACIPR4_RS02680 ^@ http://purl.uniprot.org/uniprot/E8V3W2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/401053:ACIPR4_RS18205 ^@ http://purl.uniprot.org/uniprot/E8UZR4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS01700 ^@ http://purl.uniprot.org/uniprot/E8V1I6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/401053:ACIPR4_RS06750 ^@ http://purl.uniprot.org/uniprot/E8V018 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS16085 ^@ http://purl.uniprot.org/uniprot/E8V807 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/401053:ACIPR4_RS10890 ^@ http://purl.uniprot.org/uniprot/E8V8K9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS20175 ^@ http://purl.uniprot.org/uniprot/E8V4G6 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/401053:ACIPR4_RS17640 ^@ http://purl.uniprot.org/uniprot/E8UYS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS16525 ^@ http://purl.uniprot.org/uniprot/E8V8P1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/401053:ACIPR4_RS17800 ^@ http://purl.uniprot.org/uniprot/E8UYW0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS03520 ^@ http://purl.uniprot.org/uniprot/E8V5K5 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/401053:ACIPR4_RS16310 ^@ http://purl.uniprot.org/uniprot/E8V854 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS16510 ^@ http://purl.uniprot.org/uniprot/E8V8N8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/401053:ACIPR4_RS13415 ^@ http://purl.uniprot.org/uniprot/E8V1Y4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS19490 ^@ http://purl.uniprot.org/uniprot/E8V2W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS12680 ^@ http://purl.uniprot.org/uniprot/E8V0A8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS19280 ^@ http://purl.uniprot.org/uniprot/E8V260 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/401053:ACIPR4_RS03430 ^@ http://purl.uniprot.org/uniprot/E8V5I8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/401053:ACIPR4_RS14955 ^@ http://purl.uniprot.org/uniprot/E8V580 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS07440 ^@ http://purl.uniprot.org/uniprot/E8V1N1 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/401053:ACIPR4_RS13595 ^@ http://purl.uniprot.org/uniprot/E8V2N1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS01195 ^@ http://purl.uniprot.org/uniprot/E8V0M1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS15960 ^@ http://purl.uniprot.org/uniprot/E8V7J0 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/401053:ACIPR4_RS20315 ^@ http://purl.uniprot.org/uniprot/E8V4J4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS18790 ^@ http://purl.uniprot.org/uniprot/E8V1A6 ^@ Similarity ^@ Belongs to the TrbI/VirB10 family. http://togogenome.org/gene/401053:ACIPR4_RS21195 ^@ http://purl.uniprot.org/uniprot/E8V6X3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS20170 ^@ http://purl.uniprot.org/uniprot/E8V4G5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Binds a copper A center.|||Cell membrane|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/401053:ACIPR4_RS02640 ^@ http://purl.uniprot.org/uniprot/E8V3V4 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/401053:ACIPR4_RS05565 ^@ http://purl.uniprot.org/uniprot/E8UXK0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/401053:ACIPR4_RS07225 ^@ http://purl.uniprot.org/uniprot/E8V0Y0 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/401053:ACIPR4_RS06815 ^@ http://purl.uniprot.org/uniprot/E8V031 ^@ Subunit ^@ Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/401053:ACIPR4_RS20415 ^@ http://purl.uniprot.org/uniprot/E8V4L5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS07410 ^@ http://purl.uniprot.org/uniprot/E8V1M5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS16745 ^@ http://purl.uniprot.org/uniprot/E8V8T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS12780 ^@ http://purl.uniprot.org/uniprot/E8V0C7 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/401053:ACIPR4_RS16070 ^@ http://purl.uniprot.org/uniprot/E8V804 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/401053:ACIPR4_RS16655 ^@ http://purl.uniprot.org/uniprot/E8V8R8 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS15575 ^@ http://purl.uniprot.org/uniprot/E8V6U2 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/401053:ACIPR4_RS15210 ^@ http://purl.uniprot.org/uniprot/E8V5Z9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/401053:ACIPR4_RS17880 ^@ http://purl.uniprot.org/uniprot/E8UZK0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/401053:ACIPR4_RS19365 ^@ http://purl.uniprot.org/uniprot/E8V2T5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/401053:ACIPR4_RS18690 ^@ http://purl.uniprot.org/uniprot/E8V186 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/401053:ACIPR4_RS02625 ^@ http://purl.uniprot.org/uniprot/E8V3V1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/401053:ACIPR4_RS08510 ^@ http://purl.uniprot.org/uniprot/E8V428 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/401053:ACIPR4_RS17795 ^@ http://purl.uniprot.org/uniprot/E8UYV9 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/401053:ACIPR4_RS02525 ^@ http://purl.uniprot.org/uniprot/E8V369 ^@ Similarity ^@ Belongs to the transketolase family. http://togogenome.org/gene/401053:ACIPR4_RS08980 ^@ http://purl.uniprot.org/uniprot/E8V4Y3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/401053:ACIPR4_RS03645 ^@ http://purl.uniprot.org/uniprot/E8V5M9 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/401053:ACIPR4_RS14760 ^@ http://purl.uniprot.org/uniprot/E8V541 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/401053:ACIPR4_RS20440 ^@ http://purl.uniprot.org/uniprot/E8V585 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/401053:ACIPR4_RS11680 ^@ http://purl.uniprot.org/uniprot/E8UXW8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS03975 ^@ http://purl.uniprot.org/uniprot/E8V6G2 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/401053:ACIPR4_RS13540 ^@ http://purl.uniprot.org/uniprot/E8V2M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS16035 ^@ http://purl.uniprot.org/uniprot/E8V7K5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/401053:ACIPR4_RS06080 ^@ http://purl.uniprot.org/uniprot/E8UYF4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/401053:ACIPR4_RS04230 ^@ http://purl.uniprot.org/uniprot/E8V739 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/401053:ACIPR4_RS16875 ^@ http://purl.uniprot.org/uniprot/E8UXC5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/401053:ACIPR4_RS07185 ^@ http://purl.uniprot.org/uniprot/E8V0X2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/401053:ACIPR4_RS09185 ^@ http://purl.uniprot.org/uniprot/E8V5P3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/401053:ACIPR4_RS12800 ^@ http://purl.uniprot.org/uniprot/E8V101 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/401053:ACIPR4_RS14785 ^@ http://purl.uniprot.org/uniprot/E8V546 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS14850 ^@ http://purl.uniprot.org/uniprot/E8V559 ^@ Similarity ^@ Belongs to the BshC family. http://togogenome.org/gene/401053:ACIPR4_RS15630 ^@ http://purl.uniprot.org/uniprot/E8V6V3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS08865 ^@ http://purl.uniprot.org/uniprot/E8V4W0 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/401053:ACIPR4_RS20630 ^@ http://purl.uniprot.org/uniprot/E8V5C6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/401053:ACIPR4_RS01285 ^@ http://purl.uniprot.org/uniprot/E8V0N9 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/401053:ACIPR4_RS17335 ^@ http://purl.uniprot.org/uniprot/E8UY02 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/401053:ACIPR4_RS19070 ^@ http://purl.uniprot.org/uniprot/E8V220 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/401053:ACIPR4_RS04095 ^@ http://purl.uniprot.org/uniprot/E8V711 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/401053:ACIPR4_RS09405 ^@ http://purl.uniprot.org/uniprot/E8V5T6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/401053:ACIPR4_RS13510 ^@ http://purl.uniprot.org/uniprot/E8V2L4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/401053:ACIPR4_RS16810 ^@ http://purl.uniprot.org/uniprot/E8UXB2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS09425 ^@ http://purl.uniprot.org/uniprot/E8V5U1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/401053:ACIPR4_RS14675 ^@ http://purl.uniprot.org/uniprot/E8V526 ^@ Similarity ^@ Belongs to the TrbI/VirB10 family. http://togogenome.org/gene/401053:ACIPR4_RS10685 ^@ http://purl.uniprot.org/uniprot/E8V8G8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/401053:ACIPR4_RS03620 ^@ http://purl.uniprot.org/uniprot/E8V5M4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/401053:ACIPR4_RS16095 ^@ http://purl.uniprot.org/uniprot/E8V809 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/401053:ACIPR4_RS06845 ^@ http://purl.uniprot.org/uniprot/E8V037 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/401053:ACIPR4_RS04605 ^@ http://purl.uniprot.org/uniprot/E8V7Q6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell inner membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/401053:ACIPR4_RS07585 ^@ http://purl.uniprot.org/uniprot/E8V1Q9 ^@ Function|||Similarity ^@ Belongs to the transposase IS30 family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/401053:ACIPR4_RS19170 ^@ http://purl.uniprot.org/uniprot/E8V239 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/401053:ACIPR4_RS03190 ^@ http://purl.uniprot.org/uniprot/E8V4S1 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/401053:ACIPR4_RS19000 ^@ http://purl.uniprot.org/uniprot/E8V205 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS01070 ^@ http://purl.uniprot.org/uniprot/E8UZY1 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS03560 ^@ http://purl.uniprot.org/uniprot/E8V5L3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/401053:ACIPR4_RS04025 ^@ http://purl.uniprot.org/uniprot/E8V6H2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS10325 ^@ http://purl.uniprot.org/uniprot/E8V7V2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/401053:ACIPR4_RS16100 ^@ http://purl.uniprot.org/uniprot/E8V810 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/401053:ACIPR4_RS06915 ^@ http://purl.uniprot.org/uniprot/E8V052 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS01680 ^@ http://purl.uniprot.org/uniprot/E8V1I2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/401053:ACIPR4_RS10185 ^@ http://purl.uniprot.org/uniprot/E8V7D5 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/401053:ACIPR4_RS11970 ^@ http://purl.uniprot.org/uniprot/E8UYN7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/401053:ACIPR4_RS09045 ^@ http://purl.uniprot.org/uniprot/E8V4Z6 ^@ Similarity ^@ Belongs to the FlgD family. http://togogenome.org/gene/401053:ACIPR4_RS03450 ^@ http://purl.uniprot.org/uniprot/E8V5J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/401053:ACIPR4_RS12755 ^@ http://purl.uniprot.org/uniprot/E8V0C2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/401053:ACIPR4_RS17895 ^@ http://purl.uniprot.org/uniprot/E8UZK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS03330 ^@ http://purl.uniprot.org/uniprot/E8V5G9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/401053:ACIPR4_RS16125 ^@ http://purl.uniprot.org/uniprot/E8V815 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/401053:ACIPR4_RS15315 ^@ http://purl.uniprot.org/uniprot/E8V621 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/401053:ACIPR4_RS01900 ^@ http://purl.uniprot.org/uniprot/E8V287 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/401053:ACIPR4_RS16000 ^@ http://purl.uniprot.org/uniprot/E8V7J8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/401053:ACIPR4_RS10600 ^@ http://purl.uniprot.org/uniprot/E8V8F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/401053:ACIPR4_RS21215 ^@ http://purl.uniprot.org/uniprot/E8V6X7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell inner membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/401053:ACIPR4_RS11235 ^@ http://purl.uniprot.org/uniprot/E8UX94 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/401053:ACIPR4_RS03500 ^@ http://purl.uniprot.org/uniprot/E8V5K2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm