http://togogenome.org/gene/42253:NITMOv2_RS07620 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBV1 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/42253:NITMOv2_RS09970 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD82 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS13655 ^@ http://purl.uniprot.org/uniprot/A0A0K2GET3 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/42253:NITMOv2_RS09500 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD12 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/42253:NITMOv2_RS21430 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJK2 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/42253:NITMOv2_RS14890 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFB6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS17645 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS00125 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS10135 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/42253:NITMOv2_RS02415 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7N7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS15230 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFI8 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/42253:NITMOv2_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9C3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. PqqE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).|||Interacts with PqqD. The interaction is necessary for activity of PqqE. http://togogenome.org/gene/42253:NITMOv2_RS07450 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB07 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/42253:NITMOv2_RS15355 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGJ1 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/42253:NITMOv2_RS16590 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGD3 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/42253:NITMOv2_RS11395 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD46 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-69 and Arg-72) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. http://togogenome.org/gene/42253:NITMOv2_RS07510 ^@ http://purl.uniprot.org/uniprot/A0A088NAA0 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/42253:NITMOv2_RS13705 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEJ2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/42253:NITMOv2_RS00020 ^@ http://purl.uniprot.org/uniprot/A0A0K2G694 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/42253:NITMOv2_RS00230 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7D1 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/42253:NITMOv2_RS10075 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family.|||Cell outer membrane|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/42253:NITMOv2_RS06860 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS13755 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEL2 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/42253:NITMOv2_RS17530 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGX4 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Short' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Non-allosteric. http://togogenome.org/gene/42253:NITMOv2_RS06785 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBF3 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/42253:NITMOv2_RS20585 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/42253:NITMOv2_RS11610 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDA4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS02935 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS08825 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBI9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS06530 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAD7 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/42253:NITMOv2_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A0K2G972 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS19095 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI53 ^@ Similarity ^@ Belongs to the UPF0276 family. http://togogenome.org/gene/42253:NITMOv2_RS04300 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8V5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS19975 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIC6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS15175 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS18550 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHM4 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/42253:NITMOv2_RS15105 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFQ7 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/42253:NITMOv2_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9D0 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/42253:NITMOv2_RS15760 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFV1 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/42253:NITMOv2_RS09615 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC22 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/42253:NITMOv2_RS02920 ^@ http://purl.uniprot.org/uniprot/A0A0K2G888 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS01215 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial glucokinase family.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS09145 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC32 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS21230 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJG0 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/42253:NITMOv2_RS00780 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7N3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS12685 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEW4 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/42253:NITMOv2_RS15215 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFI0 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/42253:NITMOv2_RS21735 ^@ http://purl.uniprot.org/uniprot/A0A0K2GKF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane http://togogenome.org/gene/42253:NITMOv2_RS00890 ^@ http://purl.uniprot.org/uniprot/A0A0K2G706 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/42253:NITMOv2_RS05840 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9Q9 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/42253:NITMOv2_RS10805 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDS1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/42253:NITMOv2_RS18855 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS05935 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9T1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9L2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/42253:NITMOv2_RS20595 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIZ8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/42253:NITMOv2_RS01560 ^@ http://purl.uniprot.org/uniprot/A0A0K2G854 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/42253:NITMOv2_RS16375 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG95 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/42253:NITMOv2_RS02075 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7F8 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/42253:NITMOv2_RS09245 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC51 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/42253:NITMOv2_RS11065 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD70 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/42253:NITMOv2_RS09850 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD71 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/42253:NITMOv2_RS16695 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGR1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/42253:NITMOv2_RS09670 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/42253:NITMOv2_RS04000 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8W5 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/42253:NITMOv2_RS09640 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC20 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/42253:NITMOv2_RS19570 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS24735 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGE2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/42253:NITMOv2_RS13780 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEL7 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/42253:NITMOv2_RS19805 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIC4 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/42253:NITMOv2_RS04090 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8N7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/42253:NITMOv2_RS18430 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHG3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS05110 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS01285 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6Z8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/42253:NITMOv2_RS01710 ^@ http://purl.uniprot.org/uniprot/A0A0K2G759 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/42253:NITMOv2_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9M3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS20220 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS24570 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJJ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/42253:NITMOv2_RS11725 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDM8 ^@ Similarity ^@ Belongs to the XFP family. http://togogenome.org/gene/42253:NITMOv2_RS17525 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH77 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/42253:NITMOv2_RS19770 ^@ http://purl.uniprot.org/uniprot/A0A0K2GII3 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/42253:NITMOv2_RS11965 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS20915 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ00 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/42253:NITMOv2_RS15720 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFT4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/42253:NITMOv2_RS08690 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCI1 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/42253:NITMOv2_RS19890 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ89 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/42253:NITMOv2_RS10885 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS00035 ^@ http://purl.uniprot.org/uniprot/A0A0K2G668 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/42253:NITMOv2_RS05300 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9E4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS05830 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9Q4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/42253:NITMOv2_RS15870 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFX8 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/42253:NITMOv2_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7J8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/42253:NITMOv2_RS21425 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS19220 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI75 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS15170 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFH0 ^@ Activity Regulation|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer. http://togogenome.org/gene/42253:NITMOv2_RS04475 ^@ http://purl.uniprot.org/uniprot/A0A0K2G904 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/42253:NITMOv2_RS20395 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIQ0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/42253:NITMOv2_RS05525 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9S8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/42253:NITMOv2_RS08450 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBC6 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/42253:NITMOv2_RS09635 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC26 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/42253:NITMOv2_RS20565 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIR2 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/42253:NITMOv2_RS19125 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI56 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS02965 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Z5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/42253:NITMOv2_RS19745 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIH9 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/42253:NITMOv2_RS18720 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHQ6 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/42253:NITMOv2_RS14670 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFH4 ^@ Similarity|||Subunit ^@ Belongs to the multicopper oxidase family.|||Homotrimer. http://togogenome.org/gene/42253:NITMOv2_RS16540 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGC5 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/42253:NITMOv2_RS20755 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ41 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/42253:NITMOv2_RS12745 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE79 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/42253:NITMOv2_RS07780 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAZ3 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/42253:NITMOv2_RS04190 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS18705 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHM2 ^@ Function|||Similarity ^@ Belongs to the ferredoxin thioredoxin reductase beta subunit family.|||Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin. http://togogenome.org/gene/42253:NITMOv2_RS06595 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA86 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/42253:NITMOv2_RS09420 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC83 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS15035 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFD6 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/42253:NITMOv2_RS16385 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG81 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/42253:NITMOv2_RS15735 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFU3 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/42253:NITMOv2_RS03870 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8I8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/42253:NITMOv2_RS17025 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS21375 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS09465 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBZ8 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/42253:NITMOv2_RS08585 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCF5 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/42253:NITMOv2_RS21290 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ84 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/42253:NITMOv2_RS01510 ^@ http://purl.uniprot.org/uniprot/A0A0K2G762 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/42253:NITMOv2_RS17350 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGS4 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/42253:NITMOv2_RS09530 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS21970 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS08250 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB96 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/42253:NITMOv2_RS03980 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8N3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/42253:NITMOv2_RS02840 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7X0 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS15835 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFW6 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/42253:NITMOv2_RS14640 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF60 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/42253:NITMOv2_RS01310 ^@ http://purl.uniprot.org/uniprot/A0A0K2G703 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS07155 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAL1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer.|||Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). http://togogenome.org/gene/42253:NITMOv2_RS17855 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHE8 ^@ Similarity ^@ Belongs to the XFP family. http://togogenome.org/gene/42253:NITMOv2_RS12620 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS21660 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJR8 ^@ Function|||Similarity ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane. http://togogenome.org/gene/42253:NITMOv2_RS11495 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE94 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS07310 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAX8 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/42253:NITMOv2_RS00050 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6I5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS16345 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG72 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/42253:NITMOv2_RS01455 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7B9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/42253:NITMOv2_RS02790 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7W0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/42253:NITMOv2_RS00150 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS01685 ^@ http://purl.uniprot.org/uniprot/A0A0K2G754 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/42253:NITMOv2_RS06225 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA72 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS02875 ^@ http://purl.uniprot.org/uniprot/A0A0K2G802 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS08565 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBF1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS03645 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8G0 ^@ Function|||Similarity ^@ Belongs to the PemK/MazF family.|||Toxic component of a type II toxin-antitoxin (TA) system. http://togogenome.org/gene/42253:NITMOv2_RS20315 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIU9 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/42253:NITMOv2_RS08130 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB73 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/42253:NITMOv2_RS21260 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ75 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/42253:NITMOv2_RS07845 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB06 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/42253:NITMOv2_RS08380 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCB0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS03770 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9H3 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/42253:NITMOv2_RS09930 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCI5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/42253:NITMOv2_RS10090 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCC9 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/42253:NITMOv2_RS05295 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAE1 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/42253:NITMOv2_RS00595 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6U9 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/42253:NITMOv2_RS02050 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7F5 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/42253:NITMOv2_RS01025 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6S1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/42253:NITMOv2_RS18220 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHB2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS20550 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIS6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family. http://togogenome.org/gene/42253:NITMOv2_RS04375 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8T8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/42253:NITMOv2_RS20960 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJA6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS04355 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8T3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the THI4 family.|||Homooctamer; tetramer of dimers.|||Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS03930 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8M2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS03395 ^@ http://purl.uniprot.org/uniprot/A0A0K2G884 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS08155 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB77 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/42253:NITMOv2_RS04030 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8P4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/42253:NITMOv2_RS16200 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG44 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/42253:NITMOv2_RS03100 ^@ http://purl.uniprot.org/uniprot/A0A0K2G916 ^@ Function|||Similarity ^@ Belongs to the Ap4A hydrolase family.|||Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP. http://togogenome.org/gene/42253:NITMOv2_RS22020 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the kinesin light chain family.|||cytoskeleton http://togogenome.org/gene/42253:NITMOv2_RS06565 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB93 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/42253:NITMOv2_RS06210 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9X3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/42253:NITMOv2_RS18865 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIQ3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/42253:NITMOv2_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAG0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS15945 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFZ5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/42253:NITMOv2_RS00765 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6Y2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/42253:NITMOv2_RS01190 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6V5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS20340 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIL4 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/42253:NITMOv2_RS05105 ^@ http://purl.uniprot.org/uniprot/A0A0K2G989 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS16985 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGW8 ^@ Similarity ^@ Belongs to the TolB family. http://togogenome.org/gene/42253:NITMOv2_RS07395 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAR5 ^@ Caution|||Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS05500 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9J8 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/42253:NITMOv2_RS12835 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE14 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/42253:NITMOv2_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9W5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/42253:NITMOv2_RS05605 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9L7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/42253:NITMOv2_RS07960 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB33 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/42253:NITMOv2_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A0K2G721 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS06720 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBC3 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/42253:NITMOv2_RS00675 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6P3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS09870 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CheZ family.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS04545 ^@ http://purl.uniprot.org/uniprot/A0A0K2G919 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueG family.|||Binds 2 [4Fe-4S] clusters per monomer.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/42253:NITMOv2_RS11520 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE99 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/42253:NITMOv2_RS03925 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8V2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/42253:NITMOv2_RS22255 ^@ http://purl.uniprot.org/uniprot/A0A0K2GK39 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.|||Cell membrane|||Forms a complex with DabB.|||Part of an energy-coupled inorganic carbon pump. http://togogenome.org/gene/42253:NITMOv2_RS17790 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHD2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/42253:NITMOv2_RS13775 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEK8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS00705 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6K9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS19860 ^@ http://purl.uniprot.org/uniprot/A0A0K2GID4 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/42253:NITMOv2_RS11410 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDE5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/42253:NITMOv2_RS08080 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC42 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/42253:NITMOv2_RS20590 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIR7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/42253:NITMOv2_RS13430 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFD8 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/42253:NITMOv2_RS08550 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBE5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/42253:NITMOv2_RS01495 ^@ http://purl.uniprot.org/uniprot/A0A0K2G838 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/42253:NITMOv2_RS21680 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/42253:NITMOv2_RS04560 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA22 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS21875 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJL2 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/42253:NITMOv2_RS02490 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Q1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS21200 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ65 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/42253:NITMOv2_RS05630 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9M2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/42253:NITMOv2_RS02900 ^@ http://purl.uniprot.org/uniprot/A0A0K2G808 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/42253:NITMOv2_RS17200 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH10 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/42253:NITMOv2_RS03885 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8I1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/42253:NITMOv2_RS22290 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJW2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS20660 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJR7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Cell membrane|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS14925 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFB8 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/42253:NITMOv2_RS20520 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIY5 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/42253:NITMOv2_RS01900 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7A0 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/42253:NITMOv2_RS20665 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIT0 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/42253:NITMOv2_RS11435 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDF1 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/42253:NITMOv2_RS04525 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8Y1 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/42253:NITMOv2_RS16380 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH73 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/42253:NITMOv2_RS15335 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFK3 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/42253:NITMOv2_RS21340 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS10810 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GmhB family.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS13840 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.|||Cell membrane|||Forms a complex with DabB.|||Part of an energy-coupled inorganic carbon pump. http://togogenome.org/gene/42253:NITMOv2_RS13115 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE66 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. http://togogenome.org/gene/42253:NITMOv2_RS11415 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD52 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/42253:NITMOv2_RS13030 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF41 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS10165 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliN/MopA/SpaO family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS03220 ^@ http://purl.uniprot.org/uniprot/A0A0K2G945 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/42253:NITMOv2_RS15340 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS02590 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Q8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the transcriptional regulatory CopG/NikR family.|||Binds 1 nickel ion per subunit.|||Transcriptional regulator. http://togogenome.org/gene/42253:NITMOv2_RS17115 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGQ0 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/42253:NITMOv2_RS21150 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS13040 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEE1 ^@ Similarity ^@ Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family. http://togogenome.org/gene/42253:NITMOv2_RS10350 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS21900 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJL7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS08200 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB86 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS11670 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDC1 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/42253:NITMOv2_RS14790 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/42253:NITMOv2_RS10025 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCK4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/42253:NITMOv2_RS21015 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ33 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS20620 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ05 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/42253:NITMOv2_RS19870 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIA3 ^@ Function ^@ Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA. http://togogenome.org/gene/42253:NITMOv2_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8B0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/42253:NITMOv2_RS00470 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8N0 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/42253:NITMOv2_RS08180 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS20120 ^@ http://purl.uniprot.org/uniprot/A0A0K2GII2 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/42253:NITMOv2_RS01620 ^@ http://purl.uniprot.org/uniprot/A0A0K2G866 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/42253:NITMOv2_RS24605 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/42253:NITMOv2_RS11665 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEC6 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/42253:NITMOv2_RS00620 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6V4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS01210 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6W0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS07735 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB62 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/42253:NITMOv2_RS10480 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TOP6A family.|||Homodimer. Heterotetramer of two Top6A and two Top6B chains.|||Relaxes both positive and negative superturns and exhibits a strong decatenase activity. http://togogenome.org/gene/42253:NITMOv2_RS12970 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEC3 ^@ Similarity ^@ Belongs to the iron/manganese superoxide dismutase family. http://togogenome.org/gene/42253:NITMOv2_RS15480 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS09660 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC24 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/42253:NITMOv2_RS09625 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC27 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS01270 ^@ http://purl.uniprot.org/uniprot/A0A0K2G780 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/42253:NITMOv2_RS09480 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC03 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/42253:NITMOv2_RS01570 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7E4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/42253:NITMOv2_RS13280 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFA3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/42253:NITMOv2_RS19230 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS17745 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH17 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/42253:NITMOv2_RS20470 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/42253:NITMOv2_RS17240 ^@ http://purl.uniprot.org/uniprot/A0A088NNS3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS10465 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCU1 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/42253:NITMOv2_RS06085 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAX0 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/42253:NITMOv2_RS15080 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFE6 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/42253:NITMOv2_RS21210 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ57 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS15880 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFX0 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS03795 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9H8 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/42253:NITMOv2_RS16365 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGJ5 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/42253:NITMOv2_RS06605 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAF4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/42253:NITMOv2_RS06765 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAB9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/42253:NITMOv2_RS01320 ^@ http://purl.uniprot.org/uniprot/A0A0K2G725 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/42253:NITMOv2_RS17650 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH19 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Arsenite methyltransferase family. http://togogenome.org/gene/42253:NITMOv2_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A0K2G663 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/42253:NITMOv2_RS02505 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Q5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/42253:NITMOv2_RS07375 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAN4 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/42253:NITMOv2_RS11110 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCZ5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/42253:NITMOv2_RS21325 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS15600 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFQ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS02805 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS17295 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGT9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS17940 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS03260 ^@ http://purl.uniprot.org/uniprot/A0A0K2G842 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9U3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/42253:NITMOv2_RS03040 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8B4 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/42253:NITMOv2_RS04155 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8Q0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/42253:NITMOv2_RS05595 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9K4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/42253:NITMOv2_RS21585 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8N0 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/42253:NITMOv2_RS01480 ^@ http://purl.uniprot.org/uniprot/A0A0K2G735 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/42253:NITMOv2_RS15635 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFQ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS10140 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDB7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/42253:NITMOv2_RS07585 ^@ http://purl.uniprot.org/uniprot/A0A088NAA9 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/42253:NITMOv2_RS00895 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6T8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/42253:NITMOv2_RS03890 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9K6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/42253:NITMOv2_RS02860 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8X2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS20265 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OmpP1/FadL family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS19390 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIB4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer.|||Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). http://togogenome.org/gene/42253:NITMOv2_RS03935 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8J0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/42253:NITMOv2_RS05280 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9F4 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/42253:NITMOv2_RS13465 ^@ http://purl.uniprot.org/uniprot/A0A0K2GED4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS12185 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEL6 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/42253:NITMOv2_RS01010 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6U2 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/42253:NITMOv2_RS04025 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8W8 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/42253:NITMOv2_RS06310 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8N0 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/42253:NITMOv2_RS11330 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD31 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/42253:NITMOv2_RS08475 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBD4 ^@ Function ^@ Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/42253:NITMOv2_RS19705 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS21250 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ66 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/42253:NITMOv2_RS07575 ^@ http://purl.uniprot.org/uniprot/A0A088NNR9 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/42253:NITMOv2_RS10525 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCV3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS22150 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJT5 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS13910 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS20365 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIN5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS09150 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBT7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS16515 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGC1 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/42253:NITMOv2_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8L9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS22170 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJS4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS15985 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG89 ^@ Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family. http://togogenome.org/gene/42253:NITMOv2_RS05420 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9R1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS19410 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI05 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/42253:NITMOv2_RS07410 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS15250 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFI1 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/42253:NITMOv2_RS20330 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/42253:NITMOv2_RS06935 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/42253:NITMOv2_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAL7 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/42253:NITMOv2_RS05615 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/42253:NITMOv2_RS16105 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG40 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS19885 ^@ http://purl.uniprot.org/uniprot/A0A0K2GID9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS14460 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFD0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/42253:NITMOv2_RS16330 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH65 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/42253:NITMOv2_RS07390 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAZ4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/42253:NITMOv2_RS03810 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8J1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCD3 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/42253:NITMOv2_RS18160 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS18055 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI74 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/42253:NITMOv2_RS10035 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCA1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/42253:NITMOv2_RS05645 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9L5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/42253:NITMOv2_RS08005 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8N0 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/42253:NITMOv2_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFE8 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/42253:NITMOv2_RS08170 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB58 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/42253:NITMOv2_RS15920 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFY9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS16560 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGB6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/42253:NITMOv2_RS02440 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS15710 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFT7 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/42253:NITMOv2_RS00290 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7D8 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/42253:NITMOv2_RS08560 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCE9 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/42253:NITMOv2_RS03955 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8M7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS04405 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8X1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS21745 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJT6 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/42253:NITMOv2_RS02285 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8M8 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/42253:NITMOv2_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS10660 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCN9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/42253:NITMOv2_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6K8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS16215 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS12285 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDP2 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/42253:NITMOv2_RS02450 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7R5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS20310 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIK2 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS21070 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ43 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS08820 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/42253:NITMOv2_RS18725 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIM7 ^@ Similarity ^@ Belongs to the CbbQ/NirQ/NorQ/GpvN family. http://togogenome.org/gene/42253:NITMOv2_RS22190 ^@ http://purl.uniprot.org/uniprot/A0A0K2GK24 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/42253:NITMOv2_RS05580 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9L3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/42253:NITMOv2_RS19855 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/42253:NITMOv2_RS12475 ^@ http://purl.uniprot.org/uniprot/A0A0K2GER4 ^@ Similarity ^@ In the N-terminal section; belongs to the phytochrome family. http://togogenome.org/gene/42253:NITMOv2_RS12415 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE13 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/42253:NITMOv2_RS10820 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCS6 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/42253:NITMOv2_RS09175 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBU2 ^@ Cofactor|||Similarity ^@ Belongs to the truncated hemoglobin family. Group I subfamily.|||Binds 1 heme group per subunit. http://togogenome.org/gene/42253:NITMOv2_RS16955 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHH8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/42253:NITMOv2_RS01345 ^@ http://purl.uniprot.org/uniprot/A0A0K2G730 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/42253:NITMOv2_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6U5 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/42253:NITMOv2_RS05710 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9K7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/42253:NITMOv2_RS10030 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCA7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/42253:NITMOv2_RS11660 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDB4 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/42253:NITMOv2_RS06945 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8N0 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/42253:NITMOv2_RS15390 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFL2 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/42253:NITMOv2_RS17825 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH55 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/42253:NITMOv2_RS02640 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8U0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/42253:NITMOv2_RS22070 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJQ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/42253:NITMOv2_RS02495 ^@ http://purl.uniprot.org/uniprot/A0A0K2G801 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS12345 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDP6 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/42253:NITMOv2_RS12865 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEA1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS01380 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7A3 ^@ Function|||Similarity ^@ Belongs to the anhydro-N-acetylmuramic acid kinase family.|||Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/42253:NITMOv2_RS14120 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS05625 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9U8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/42253:NITMOv2_RS01800 ^@ http://purl.uniprot.org/uniprot/A0A0K2G776 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS20615 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/42253:NITMOv2_RS16265 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGH6 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/42253:NITMOv2_RS16995 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/42253:NITMOv2_RS05530 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9K3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/42253:NITMOv2_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAR7 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/42253:NITMOv2_RS00870 ^@ http://purl.uniprot.org/uniprot/A0A0K2G702 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS09010 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBX8 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/42253:NITMOv2_RS06010 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9V5 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS11840 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDE8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS04380 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9W9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS17030 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHJ2 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/42253:NITMOv2_RS19070 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS21380 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJJ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS02390 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7N2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/42253:NITMOv2_RS02475 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7R9 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/42253:NITMOv2_RS20390 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/42253:NITMOv2_RS03940 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9L6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS15975 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGY4 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/42253:NITMOv2_RS00685 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7L4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS06735 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA96 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HsdR family.|||Subunit R is required for both nuclease and ATPase activities, but not for modification.|||The type I restriction/modification system is composed of three polypeptides R, M and S. http://togogenome.org/gene/42253:NITMOv2_RS17820 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS11940 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS10170 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCE3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS09505 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC06 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS15225 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFH7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS00120 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6A9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/42253:NITMOv2_RS08840 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS14255 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS12880 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF08 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS00515 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6T1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/42253:NITMOv2_RS03085 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8C4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS21650 ^@ http://purl.uniprot.org/uniprot/A0A0K2GKD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS03025 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Z2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/42253:NITMOv2_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9G1 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/42253:NITMOv2_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8W6 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/42253:NITMOv2_RS09400 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBY3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/42253:NITMOv2_RS04220 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9S9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M32 family.|||Binds 1 zinc ion per subunit.|||Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. http://togogenome.org/gene/42253:NITMOv2_RS06440 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS00835 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6R0 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/42253:NITMOv2_RS14875 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFA8 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/42253:NITMOv2_RS10055 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCB3 ^@ Similarity ^@ Belongs to the FlgM family. http://togogenome.org/gene/42253:NITMOv2_RS08465 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS09990 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC91 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/42253:NITMOv2_RS12105 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OmpP1/FadL family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS07485 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6Q1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS05575 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9T8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/42253:NITMOv2_RS10045 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCB9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/42253:NITMOv2_RS05990 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9S5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/42253:NITMOv2_RS03965 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9M1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS15545 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGN6 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/42253:NITMOv2_RS21370 ^@ http://purl.uniprot.org/uniprot/A0A0K2GK87 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/42253:NITMOv2_RS10320 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCH9 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/42253:NITMOv2_RS08065 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBD1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/42253:NITMOv2_RS13890 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEP7 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS06460 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA55 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/42253:NITMOv2_RS15970 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG00 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/42253:NITMOv2_RS17550 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH83 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/42253:NITMOv2_RS05675 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9V7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/42253:NITMOv2_RS11485 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD80 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS04530 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA17 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS06650 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA97 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/42253:NITMOv2_RS01275 ^@ http://purl.uniprot.org/uniprot/A0A0K2G715 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS10595 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCN8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/42253:NITMOv2_RS16900 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGI3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/42253:NITMOv2_RS10890 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDU1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/42253:NITMOv2_RS16745 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS18675 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIL7 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/42253:NITMOv2_RS20625 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIU1 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS18165 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS12905 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF14 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/42253:NITMOv2_RS07755 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAY8 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/42253:NITMOv2_RS07475 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAT3 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/42253:NITMOv2_RS02915 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Y5 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/42253:NITMOv2_RS05650 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9V3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/42253:NITMOv2_RS19730 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIB1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS02850 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Z7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS15030 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFP1 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/42253:NITMOv2_RS08400 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBB7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS21995 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJN9 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/42253:NITMOv2_RS03255 ^@ http://purl.uniprot.org/uniprot/A0A0K2G880 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/42253:NITMOv2_RS05360 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAF6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS14905 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.|||Cell membrane|||Forms a complex with DabB.|||Part of an energy-coupled inorganic carbon pump. http://togogenome.org/gene/42253:NITMOv2_RS18025 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHA0 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/42253:NITMOv2_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7T2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/42253:NITMOv2_RS22145 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJR9 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS12395 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDQ6 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/42253:NITMOv2_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A0K2G879 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/42253:NITMOv2_RS00325 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6N4 ^@ Similarity ^@ Belongs to the beta-eliminating lyase family. http://togogenome.org/gene/42253:NITMOv2_RS04490 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8Y6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/42253:NITMOv2_RS03325 ^@ http://purl.uniprot.org/uniprot/A0A0K2G895 ^@ Similarity ^@ Belongs to the terpene cyclase/mutase family. http://togogenome.org/gene/42253:NITMOv2_RS04935 ^@ http://purl.uniprot.org/uniprot/A0A0K2G986 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS14160 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF67 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/42253:NITMOv2_RS13435 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS08415 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS16240 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGH0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/42253:NITMOv2_RS04365 ^@ http://purl.uniprot.org/uniprot/A0A0K2G935 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 3 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS06045 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/42253:NITMOv2_RS19415 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS18175 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS08810 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBK5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/42253:NITMOv2_RS17275 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHP4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/42253:NITMOv2_RS04875 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA77 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/42253:NITMOv2_RS09815 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC64 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/42253:NITMOv2_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9N7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/42253:NITMOv2_RS04095 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8Y0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS19240 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI80 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/42253:NITMOv2_RS11960 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS21120 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJD6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/42253:NITMOv2_RS00225 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6A2 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/42253:NITMOv2_RS05585 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9I2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS16435 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGL0 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/42253:NITMOv2_RS14845 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF97 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/42253:NITMOv2_RS17305 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGR5 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/42253:NITMOv2_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8T7 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A0K2G982 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/42253:NITMOv2_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A0K2G792 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/42253:NITMOv2_RS02270 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7V8 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/42253:NITMOv2_RS19115 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIU5 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Arsenite methyltransferase family. http://togogenome.org/gene/42253:NITMOv2_RS05715 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAM5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/42253:NITMOv2_RS01445 ^@ http://purl.uniprot.org/uniprot/A0A0K2G826 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/42253:NITMOv2_RS13665 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEJ0 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/42253:NITMOv2_RS05880 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9Q0 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/42253:NITMOv2_RS11810 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEE9 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/42253:NITMOv2_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAM2 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/42253:NITMOv2_RS04370 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8W7 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/42253:NITMOv2_RS20765 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIX5 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/42253:NITMOv2_RS04665 ^@ http://purl.uniprot.org/uniprot/A0A0K2G917 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/42253:NITMOv2_RS07760 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB65 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS09960 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC92 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/42253:NITMOv2_RS10710 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCP9 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/42253:NITMOv2_RS10610 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS01540 ^@ http://purl.uniprot.org/uniprot/A0A0K2G849 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/42253:NITMOv2_RS05885 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAR8 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/42253:NITMOv2_RS09440 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBZ2 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/42253:NITMOv2_RS07885 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB89 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family. http://togogenome.org/gene/42253:NITMOv2_RS04615 ^@ http://purl.uniprot.org/uniprot/A0A0K2G907 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS22110 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJR1 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/42253:NITMOv2_RS04485 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/42253:NITMOv2_RS18600 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIK6 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/42253:NITMOv2_RS20955 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ10 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/42253:NITMOv2_RS17750 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH40 ^@ Similarity ^@ Belongs to the aminoglycoside phosphotransferase family. http://togogenome.org/gene/42253:NITMOv2_RS18525 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS15765 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGT3 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS00130 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/42253:NITMOv2_RS16980 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHI3 ^@ Similarity ^@ Belongs to the Pal lipoprotein family. http://togogenome.org/gene/42253:NITMOv2_RS00950 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6U8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS18965 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHR7 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/42253:NITMOv2_RS17540 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHV6 ^@ Similarity ^@ In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/42253:NITMOv2_RS02830 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7V2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS09560 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCB2 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/42253:NITMOv2_RS01295 ^@ http://purl.uniprot.org/uniprot/A0A0K2G720 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/42253:NITMOv2_RS15500 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS01335 ^@ http://purl.uniprot.org/uniprot/A0A0K2G708 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/42253:NITMOv2_RS05730 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9P3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/42253:NITMOv2_RS15520 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGN1 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/42253:NITMOv2_RS08470 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBL2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS00525 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6G8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/42253:NITMOv2_RS13760 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS10645 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS21350 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ86 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/42253:NITMOv2_RS03010 ^@ http://purl.uniprot.org/uniprot/A0A0K2G806 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS03205 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8E9 ^@ Cofactor|||Similarity ^@ Belongs to the monomeric-type IDH family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS13825 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFP7 ^@ Similarity ^@ In the N-terminal section; belongs to the phytochrome family. http://togogenome.org/gene/42253:NITMOv2_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB79 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/42253:NITMOv2_RS09645 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD35 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/42253:NITMOv2_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBD2 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS16460 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGL5 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/42253:NITMOv2_RS20295 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIL6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/42253:NITMOv2_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A0K2G736 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS11715 ^@ http://purl.uniprot.org/uniprot/A0A0K2GED2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/42253:NITMOv2_RS00845 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6S9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/42253:NITMOv2_RS15065 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGC7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.|||Cell membrane|||Forms a complex with DabB.|||Part of an energy-coupled inorganic carbon pump. http://togogenome.org/gene/42253:NITMOv2_RS16925 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGI8 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/42253:NITMOv2_RS18610 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHL2 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/42253:NITMOv2_RS15910 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG70 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/42253:NITMOv2_RS04015 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9N1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/42253:NITMOv2_RS03090 ^@ http://purl.uniprot.org/uniprot/A0A0K2G846 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/42253:NITMOv2_RS11140 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD78 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/42253:NITMOv2_RS05590 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9S8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/42253:NITMOv2_RS17255 ^@ http://purl.uniprot.org/uniprot/A0A088ND37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS21820 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJL8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS21295 ^@ http://purl.uniprot.org/uniprot/A0A0K2GK69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/42253:NITMOv2_RS19680 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIA1 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/42253:NITMOv2_RS13955 ^@ http://purl.uniprot.org/uniprot/A0A0K2GER1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/42253:NITMOv2_RS15470 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGM0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS08505 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBC4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/42253:NITMOv2_RS18465 ^@ http://purl.uniprot.org/uniprot/A0A0K2GII0 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/42253:NITMOv2_RS05150 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS19675 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI87 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/42253:NITMOv2_RS10180 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCD6 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/42253:NITMOv2_RS16890 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGH8 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/42253:NITMOv2_RS05550 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9T3 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/42253:NITMOv2_RS20035 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIN3 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/42253:NITMOv2_RS12200 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDL7 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/42253:NITMOv2_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS06050 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9V6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/42253:NITMOv2_RS21240 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS03225 ^@ http://purl.uniprot.org/uniprot/A0A0K2G850 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/42253:NITMOv2_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A088NA13 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/42253:NITMOv2_RS20900 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ09 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/42253:NITMOv2_RS02205 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7U4 ^@ Similarity ^@ Belongs to the LarC family. http://togogenome.org/gene/42253:NITMOv2_RS01440 ^@ http://purl.uniprot.org/uniprot/A0A0K2G709 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/42253:NITMOv2_RS22100 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJS5 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/42253:NITMOv2_RS01260 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Y2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/42253:NITMOv2_RS12850 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE10 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/42253:NITMOv2_RS02595 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8T2 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS03920 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8J7 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/42253:NITMOv2_RS20535 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJN8 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/42253:NITMOv2_RS02430 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7M5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS00360 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8N0 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/42253:NITMOv2_RS01080 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7T9 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/42253:NITMOv2_RS06835 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS08055 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC36 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS06775 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAE0 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/42253:NITMOv2_RS07560 ^@ http://purl.uniprot.org/uniprot/A0A088NAA6 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/42253:NITMOv2_RS04520 ^@ http://purl.uniprot.org/uniprot/A0A0K2G913 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/42253:NITMOv2_RS19875 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIK4 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/42253:NITMOv2_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A0K2G987 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/42253:NITMOv2_RS19130 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHW4 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/42253:NITMOv2_RS11465 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD63 ^@ Similarity ^@ Belongs to the phosphopentomutase family. http://togogenome.org/gene/42253:NITMOv2_RS11145 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCZ6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS00680 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6K4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS01600 ^@ http://purl.uniprot.org/uniprot/A0A0K2G758 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS15995 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG05 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS15930 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFY0 ^@ Similarity ^@ Belongs to the ycf81 family. http://togogenome.org/gene/42253:NITMOv2_RS14525 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF34 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit. http://togogenome.org/gene/42253:NITMOv2_RS17205 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGP8 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS01255 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6X0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/42253:NITMOv2_RS05890 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9R8 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/42253:NITMOv2_RS07020 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBJ9 ^@ Similarity ^@ Belongs to the peptidase S24 family. http://togogenome.org/gene/42253:NITMOv2_RS15590 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFR0 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/42253:NITMOv2_RS00425 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6E5 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/42253:NITMOv2_RS15235 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGG2 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/42253:NITMOv2_RS05655 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9M7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/42253:NITMOv2_RS08575 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBE9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS18410 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHH5 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/42253:NITMOv2_RS02455 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7N0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS01730 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane http://togogenome.org/gene/42253:NITMOv2_RS10150 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCM7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/42253:NITMOv2_RS21050 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ42 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS08460 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCC8 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/42253:NITMOv2_RS20870 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ87 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS15195 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFS8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS05820 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9N5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/42253:NITMOv2_RS15755 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFT2 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/42253:NITMOv2_RS17365 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGV6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS22250 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS03190 ^@ http://purl.uniprot.org/uniprot/A0A0K2G827 ^@ Similarity ^@ In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.|||In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. http://togogenome.org/gene/42253:NITMOv2_RS04200 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/42253:NITMOv2_RS03250 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8F8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/42253:NITMOv2_RS10980 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCV7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/42253:NITMOv2_RS24075 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH90 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/42253:NITMOv2_RS19775 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIA7 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/42253:NITMOv2_RS17935 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS02955 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7X7 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/42253:NITMOv2_RS05045 ^@ http://purl.uniprot.org/uniprot/A0A0K2G993 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/42253:NITMOv2_RS18630 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHK8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/42253:NITMOv2_RS08620 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS01955 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7D6 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/42253:NITMOv2_RS04390 ^@ http://purl.uniprot.org/uniprot/A0A0K2G941 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/42253:NITMOv2_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7V7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS09760 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP K family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS12005 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS04070 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8N1 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/42253:NITMOv2_RS09565 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC14 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/42253:NITMOv2_RS11470 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS09720 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell inner membrane|||Cell membrane|||Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS10040 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD96 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/42253:NITMOv2_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAK0 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/42253:NITMOv2_RS20350 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIP0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS00005 ^@ http://purl.uniprot.org/uniprot/A0A0K2G696 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/42253:NITMOv2_RS02910 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8X8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS22135 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJR6 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/42253:NITMOv2_RS18065 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH84 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/42253:NITMOv2_RS02240 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7I9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6P5 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/42253:NITMOv2_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A0K2G782 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family. http://togogenome.org/gene/42253:NITMOv2_RS06485 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA60 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS14815 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/42253:NITMOv2_RS09225 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBV0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 65 family. http://togogenome.org/gene/42253:NITMOv2_RS17725 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS00245 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6E1 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/42253:NITMOv2_RS05695 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9M5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/42253:NITMOv2_RS01220 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6Y4 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/42253:NITMOv2_RS12650 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDV9 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/42253:NITMOv2_RS05460 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9I0 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/42253:NITMOv2_RS10130 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Cell membrane|||Membrane|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/42253:NITMOv2_RS03030 ^@ http://purl.uniprot.org/uniprot/A0A0K2G901 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/42253:NITMOv2_RS06570 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA81 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/42253:NITMOv2_RS04105 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9Q1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/42253:NITMOv2_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A0K2G929 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS06465 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAC6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS01060 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6V2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS19280 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS00840 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6Z7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/42253:NITMOv2_RS12840 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE96 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/42253:NITMOv2_RS20275 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIL8 ^@ Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/42253:NITMOv2_RS01050 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6S5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/42253:NITMOv2_RS18735 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS17685 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHZ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS19845 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI98 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/42253:NITMOv2_RS18905 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHU0 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent DNA ligase family.|||DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. http://togogenome.org/gene/42253:NITMOv2_RS00665 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A0K2G973 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS15420 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFM8 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/42253:NITMOv2_RS20225 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS05545 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9J3 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/42253:NITMOv2_RS04710 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA48 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/42253:NITMOv2_RS01500 ^@ http://purl.uniprot.org/uniprot/A0A0K2G739 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS11345 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD37 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/42253:NITMOv2_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9M0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/42253:NITMOv2_RS02380 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7L5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/42253:NITMOv2_RS21520 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6E5 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/42253:NITMOv2_RS04565 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8Z8 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS03200 ^@ http://purl.uniprot.org/uniprot/A0A0K2G845 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aconitase/IPM isomerase family.|||Mitochondrion http://togogenome.org/gene/42253:NITMOv2_RS21085 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ36 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/42253:NITMOv2_RS16065 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG12 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS15790 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGT8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS03055 ^@ http://purl.uniprot.org/uniprot/A0A0K2G906 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/42253:NITMOv2_RS09620 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD33 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/42253:NITMOv2_RS09135 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCU7 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/42253:NITMOv2_RS15805 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS04040 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9N6 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/42253:NITMOv2_RS02940 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Z0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS19160 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHY8 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/42253:NITMOv2_RS10175 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCN2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS01615 ^@ http://purl.uniprot.org/uniprot/A0A0K2G741 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/42253:NITMOv2_RS14405 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF05 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/42253:NITMOv2_RS13205 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEH9 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/42253:NITMOv2_RS11105 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDZ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS20270 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIL1 ^@ Similarity ^@ Belongs to the 2-oxoadipate dioxygenase/decarboxylase family. http://togogenome.org/gene/42253:NITMOv2_RS16220 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG48 ^@ Function ^@ Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/42253:NITMOv2_RS16020 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG11 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/42253:NITMOv2_RS14650 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS08050 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB29 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS12150 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDK7 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/42253:NITMOv2_RS05760 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9L8 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/42253:NITMOv2_RS06140 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9Y6 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/42253:NITMOv2_RS11560 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD92 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/42253:NITMOv2_RS12845 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE01 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS05855 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9P5 ^@ Similarity ^@ Belongs to the UreD family. http://togogenome.org/gene/42253:NITMOv2_RS04775 ^@ http://purl.uniprot.org/uniprot/A0A0K2G923 ^@ Similarity ^@ Belongs to the UPF0677 family. http://togogenome.org/gene/42253:NITMOv2_RS01805 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8A9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/42253:NITMOv2_RS02445 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Z1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS18360 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHG8 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/42253:NITMOv2_RS12855 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF03 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS02975 ^@ http://purl.uniprot.org/uniprot/A0A0K2G823 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/42253:NITMOv2_RS15595 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGP6 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/42253:NITMOv2_RS16395 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG99 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/42253:NITMOv2_RS17625 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH14 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/42253:NITMOv2_RS08345 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB92 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/42253:NITMOv2_RS16595 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHB5 ^@ Similarity ^@ Belongs to the prokaryotic ubiquitin-like protein family. http://togogenome.org/gene/42253:NITMOv2_RS06230 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA01 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/42253:NITMOv2_RS06455 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB66 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/42253:NITMOv2_RS20115 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIH3 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/42253:NITMOv2_RS02780 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7U2 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||In the C-terminal section; belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||In the N-terminal section; belongs to the MobA family. http://togogenome.org/gene/42253:NITMOv2_RS10770 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCR5 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily. http://togogenome.org/gene/42253:NITMOv2_RS16960 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGJ2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/42253:NITMOv2_RS15450 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGL3 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/42253:NITMOv2_RS13745 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEV7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/42253:NITMOv2_RS16355 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS12860 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE19 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS17635 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGZ2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS08070 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS00655 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6J7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS17375 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGS9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/42253:NITMOv2_RS17580 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGY3 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/42253:NITMOv2_RS03320 ^@ http://purl.uniprot.org/uniprot/A0A0K2G869 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/42253:NITMOv2_RS21055 ^@ http://purl.uniprot.org/uniprot/A0A0K2GK23 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/42253:NITMOv2_RS16235 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG54 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/42253:NITMOv2_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6R6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/42253:NITMOv2_RS21475 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8N0 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/42253:NITMOv2_RS08280 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBH5 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/42253:NITMOv2_RS12250 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS17740 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHC2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/42253:NITMOv2_RS10570 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCN3 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/42253:NITMOv2_RS04150 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9R4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/42253:NITMOv2_RS17755 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI06 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.|||Homodimer.|||Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. http://togogenome.org/gene/42253:NITMOv2_RS05245 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9D3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS16260 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG59 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/42253:NITMOv2_RS20750 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJT8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/42253:NITMOv2_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6Y5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/42253:NITMOv2_RS04140 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8S1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS05310 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9F9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/42253:NITMOv2_RS20245 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIK5 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/42253:NITMOv2_RS03005 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8Z5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/42253:NITMOv2_RS09470 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC93 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/42253:NITMOv2_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8G8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS00175 ^@ http://purl.uniprot.org/uniprot/A0A0K2G692 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/42253:NITMOv2_RS12870 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE07 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS07555 ^@ http://purl.uniprot.org/uniprot/A0A088NA18 ^@ Similarity ^@ Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/42253:NITMOv2_RS09830 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC74 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/42253:NITMOv2_RS13735 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEK7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS05910 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAS4 ^@ Function|||Similarity ^@ Belongs to the cyanase family.|||Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. http://togogenome.org/gene/42253:NITMOv2_RS16585 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGB9 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/42253:NITMOv2_RS12245 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS02970 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8A0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/42253:NITMOv2_RS20580 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIT6 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/42253:NITMOv2_RS13095 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE60 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/42253:NITMOv2_RS09575 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/42253:NITMOv2_RS09600 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD28 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/42253:NITMOv2_RS09415 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS06475 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA35 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS15070 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFF0 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/42253:NITMOv2_RS04455 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8X3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS18795 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHR8 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/42253:NITMOv2_RS15190 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGF0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/42253:NITMOv2_RS11425 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE61 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS20610 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJQ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/42253:NITMOv2_RS03295 ^@ http://purl.uniprot.org/uniprot/A0A0K2G864 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/42253:NITMOv2_RS16325 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG85 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS03580 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8E7 ^@ Function|||Similarity ^@ Belongs to the PqqB family.|||May be involved in the transport of PQQ or its precursor to the periplasm. http://togogenome.org/gene/42253:NITMOv2_RS12895 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE12 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/42253:NITMOv2_RS11120 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS04590 ^@ http://purl.uniprot.org/uniprot/A0A0K2G902 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 63 family. http://togogenome.org/gene/42253:NITMOv2_RS09570 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/42253:NITMOv2_RS09130 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBS7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS05685 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9K2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/42253:NITMOv2_RS03800 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8H1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS11355 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE44 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS03865 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS01470 ^@ http://purl.uniprot.org/uniprot/A0A0K2G831 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS08215 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB68 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS20145 ^@ http://purl.uniprot.org/uniprot/A0A0K2GII7 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/42253:NITMOv2_RS03035 ^@ http://purl.uniprot.org/uniprot/A0A0K2G811 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/42253:NITMOv2_RS06740 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBC9 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/42253:NITMOv2_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/42253:NITMOv2_RS09810 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCG2 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/42253:NITMOv2_RS02845 ^@ http://purl.uniprot.org/uniprot/A0A0K2G873 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/42253:NITMOv2_RS14860 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS04480 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8X7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS01460 ^@ http://purl.uniprot.org/uniprot/A0A0K2G751 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/42253:NITMOv2_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7A4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS05390 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9G5 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/42253:NITMOv2_RS08895 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9J2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/42253:NITMOv2_RS07815 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS22065 ^@ http://purl.uniprot.org/uniprot/A0A0K2GK01 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/42253:NITMOv2_RS03045 ^@ http://purl.uniprot.org/uniprot/A0A0K2G836 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/42253:NITMOv2_RS19315 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MerT family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS21160 ^@ http://purl.uniprot.org/uniprot/A0A0K2GK42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS10615 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDM7 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/42253:NITMOv2_RS15730 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFS9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/42253:NITMOv2_RS19835 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIC9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/42253:NITMOv2_RS04815 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9E5 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/42253:NITMOv2_RS07765 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAZ1 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/42253:NITMOv2_RS17310 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS05445 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9I9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS11445 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/42253:NITMOv2_RS22235 ^@ http://purl.uniprot.org/uniprot/A0A0K2GK34 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/42253:NITMOv2_RS01830 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8B5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/42253:NITMOv2_RS13035 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE53 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/42253:NITMOv2_RS09445 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC88 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/42253:NITMOv2_RS01795 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7C3 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/42253:NITMOv2_RS20445 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIQ2 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/42253:NITMOv2_RS08165 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB75 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/42253:NITMOv2_RS02470 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Z6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS10760 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD04 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/42253:NITMOv2_RS16710 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHD8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6S8 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/42253:NITMOv2_RS12790 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS03915 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8I6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/42253:NITMOv2_RS15565 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFQ5 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/42253:NITMOv2_RS13120 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF63 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS09835 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS19815 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIJ3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/42253:NITMOv2_RS01575 ^@ http://purl.uniprot.org/uniprot/A0A0K2G777 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS12960 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF25 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS17615 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGY5 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/42253:NITMOv2_RS11955 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDR9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/42253:NITMOv2_RS17565 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHW2 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/42253:NITMOv2_RS02515 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/42253:NITMOv2_RS06080 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9U4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/42253:NITMOv2_RS08060 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB56 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/42253:NITMOv2_RS04420 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8V8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/42253:NITMOv2_RS10580 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCM6 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/42253:NITMOv2_RS08145 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB49 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/42253:NITMOv2_RS12045 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS16825 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGT7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS00105 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6B4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/42253:NITMOv2_RS08075 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB35 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/42253:NITMOv2_RS19750 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIA2 ^@ Similarity ^@ Belongs to the pyruvoyl-dependent arginine decarboxylase family. http://togogenome.org/gene/42253:NITMOv2_RS06925 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBH8 ^@ Function ^@ CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/42253:NITMOv2_RS15750 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG32 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/42253:NITMOv2_RS21755 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJK1 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA12 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/42253:NITMOv2_RS08370 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBB3 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/42253:NITMOv2_RS16700 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGE0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/42253:NITMOv2_RS08320 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCA0 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/42253:NITMOv2_RS05620 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9L0 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/42253:NITMOv2_RS15580 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG08 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/42253:NITMOv2_RS03785 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8I7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/42253:NITMOv2_RS16965 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGW3 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/42253:NITMOv2_RS03680 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8E6 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/42253:NITMOv2_RS17595 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH92 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/42253:NITMOv2_RS17370 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHR5 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/42253:NITMOv2_RS22180 ^@ http://purl.uniprot.org/uniprot/A0A0K2GKQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS14205 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8N0 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/42253:NITMOv2_RS03815 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS21640 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJG8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/42253:NITMOv2_RS02500 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7S4 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/42253:NITMOv2_RS10630 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCN6 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/42253:NITMOv2_RS17715 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH07 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/42253:NITMOv2_RS20905 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ14 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS09915 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/42253:NITMOv2_RS07180 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/42253:NITMOv2_RS10185 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCD2 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/42253:NITMOv2_RS11730 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDC4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/42253:NITMOv2_RS10085 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDA7 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/42253:NITMOv2_RS05900 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/42253:NITMOv2_RS06625 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA92 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS01555 ^@ http://purl.uniprot.org/uniprot/A0A0K2G732 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS20530 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIS5 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/42253:NITMOv2_RS05845 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9Z2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreF family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/42253:NITMOv2_RS12040 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDI4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS16405 ^@ http://purl.uniprot.org/uniprot/A0A0K2GG86 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/42253:NITMOv2_RS06355 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB41 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/42253:NITMOv2_RS20545 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIY9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/42253:NITMOv2_RS07400 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS18605 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHK3 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/42253:NITMOv2_RS10120 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCD4 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/42253:NITMOv2_RS11195 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD87 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/42253:NITMOv2_RS01850 ^@ http://purl.uniprot.org/uniprot/A0A0K2G788 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/42253:NITMOv2_RS07010 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/42253:NITMOv2_RS18595 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHN4 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/42253:NITMOv2_RS21655 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/42253:NITMOv2_RS15245 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFT9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/42253:NITMOv2_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Y1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9N0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/42253:NITMOv2_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAJ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/42253:NITMOv2_RS01330 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Z8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/42253:NITMOv2_RS09525 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD16 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS00305 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6F0 ^@ Similarity ^@ Belongs to the homogentisate dioxygenase family. http://togogenome.org/gene/42253:NITMOv2_RS19165 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIV3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/42253:NITMOv2_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB03 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS08910 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBV3 ^@ Similarity ^@ Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/42253:NITMOv2_RS17865 ^@ http://purl.uniprot.org/uniprot/A0A0K2GH66 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS08365 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBJ0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/42253:NITMOv2_RS01280 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6X5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/42253:NITMOv2_RS15955 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFY5 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/42253:NITMOv2_RS01650 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7F7 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/42253:NITMOv2_RS03265 ^@ http://purl.uniprot.org/uniprot/A0A0K2G955 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS14115 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/42253:NITMOv2_RS04035 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8K8 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/42253:NITMOv2_RS22140 ^@ http://purl.uniprot.org/uniprot/A0A0K2GK14 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/42253:NITMOv2_RS05865 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9R3 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS16390 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGK0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/42253:NITMOv2_RS19535 ^@ http://purl.uniprot.org/uniprot/A0A0K2GI70 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/42253:NITMOv2_RS08045 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/42253:NITMOv2_RS14900 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.|||Cell membrane|||Forms a complex with DabA.|||Membrane|||Part of an energy-coupled inorganic carbon pump. http://togogenome.org/gene/42253:NITMOv2_RS07600 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/42253:NITMOv2_RS02960 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8Y7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/42253:NITMOv2_RS13075 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE56 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/42253:NITMOv2_RS15220 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFT3 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS02985 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8Z1 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/42253:NITMOv2_RS05995 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/42253:NITMOv2_RS16690 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB87 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS00235 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6C8 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/42253:NITMOv2_RS15810 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFW2 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/42253:NITMOv2_RS07150 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBM0 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/42253:NITMOv2_RS18820 ^@ http://purl.uniprot.org/uniprot/A0A0K2GIP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS21095 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ48 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/42253:NITMOv2_RS03240 ^@ http://purl.uniprot.org/uniprot/A0A0K2G951 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBS9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/42253:NITMOv2_RS07380 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBR3 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/42253:NITMOv2_RS11600 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDA8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS15255 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFJ4 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/42253:NITMOv2_RS07570 ^@ http://purl.uniprot.org/uniprot/A0A088N9K3 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/42253:NITMOv2_RS02785 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8W2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS07340 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAQ3 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/42253:NITMOv2_RS12610 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEU8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7M1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS18690 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHM5 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/42253:NITMOv2_RS19200 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHY1 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/42253:NITMOv2_RS14770 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFJ1 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/42253:NITMOv2_RS08000 ^@ http://purl.uniprot.org/uniprot/A0A0K2GB19 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/42253:NITMOv2_RS01835 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7A9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/42253:NITMOv2_RS11440 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD60 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/42253:NITMOv2_RS13750 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS03050 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7Z9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS08430 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBA6 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/42253:NITMOv2_RS21315 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJ88 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS05555 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9K8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/42253:NITMOv2_RS02865 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7X5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS03995 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8L5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A0K2G731 ^@ Similarity ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily. http://togogenome.org/gene/42253:NITMOv2_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAX5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/42253:NITMOv2_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A0K2G781 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/42253:NITMOv2_RS12830 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEZ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||In the C-terminal section; belongs to the complex I 49 kDa subunit family.|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS08355 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/42253:NITMOv2_RS11230 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CitM (TC 2.A.11) transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS04185 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/42253:NITMOv2_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6Q3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/42253:NITMOv2_RS03095 ^@ http://purl.uniprot.org/uniprot/A0A0K2G807 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/42253:NITMOv2_RS02435 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8Q3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/42253:NITMOv2_RS15205 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS14605 ^@ http://purl.uniprot.org/uniprot/A0A0K2GF56 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS09590 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC18 ^@ Similarity ^@ Belongs to the RNA polymerase subunit omega family. http://togogenome.org/gene/42253:NITMOv2_RS22115 ^@ http://purl.uniprot.org/uniprot/A0A0K2GK10 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/42253:NITMOv2_RS09920 ^@ http://purl.uniprot.org/uniprot/A0A0K2GD77 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/42253:NITMOv2_RS13600 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEH8 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/42253:NITMOv2_RS03855 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8K5 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/42253:NITMOv2_RS00760 ^@ http://purl.uniprot.org/uniprot/A0A0K2G6P4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS12815 ^@ http://purl.uniprot.org/uniprot/A0A0K2GE91 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS13850 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFQ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS14880 ^@ http://purl.uniprot.org/uniprot/A0A0K2GFL6 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/42253:NITMOv2_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A0K2G883 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/42253:NITMOv2_RS06005 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS21395 ^@ http://purl.uniprot.org/uniprot/A0A0K2GK91 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/42253:NITMOv2_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7R0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/42253:NITMOv2_RS12080 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS03690 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8G9 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/42253:NITMOv2_RS08040 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBC5 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/42253:NITMOv2_RS04460 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA04 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS08110 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBE1 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/42253:NITMOv2_RS21840 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJK7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/42253:NITMOv2_RS15900 ^@ http://purl.uniprot.org/uniprot/A0A0K2GGW5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/42253:NITMOv2_RS17905 ^@ http://purl.uniprot.org/uniprot/A0A0K2GHF8 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/42253:NITMOv2_RS03290 ^@ http://purl.uniprot.org/uniprot/A0A0K2G958 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. FabH family. http://togogenome.org/gene/42253:NITMOv2_RS01740 ^@ http://purl.uniprot.org/uniprot/A0A0K2G787 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/42253:NITMOv2_RS20510 ^@ http://purl.uniprot.org/uniprot/A0A0K2GJN3 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/42253:NITMOv2_RS06615 ^@ http://purl.uniprot.org/uniprot/A0A0K2GA69 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/42253:NITMOv2_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A0K2G9B4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A0K2GAK4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/42253:NITMOv2_RS12805 ^@ http://purl.uniprot.org/uniprot/A0A0K2GEZ0 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/42253:NITMOv2_RS10145 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCD9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/42253:NITMOv2_RS03620 ^@ http://purl.uniprot.org/uniprot/A0A0K2G8N0 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/42253:NITMOv2_RS08195 ^@ http://purl.uniprot.org/uniprot/A0A0K2GC71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/42253:NITMOv2_RS04890 ^@ http://purl.uniprot.org/uniprot/A0A0K2G976 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/42253:NITMOv2_RS11390 ^@ http://purl.uniprot.org/uniprot/A0A0K2GDD7 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/42253:NITMOv2_RS01665 ^@ http://purl.uniprot.org/uniprot/A0A0K2G876 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/42253:NITMOv2_RS10535 ^@ http://purl.uniprot.org/uniprot/A0A0K2GCL3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/42253:NITMOv2_RS08135 ^@ http://purl.uniprot.org/uniprot/A0A0K2GBE6 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/42253:NITMOv2_RS00710 ^@ http://purl.uniprot.org/uniprot/A0A0K2G7L9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.