http://togogenome.org/gene/457570:NTHER_RS09175 ^@ http://purl.uniprot.org/uniprot/B2A5N4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/457570:NTHER_RS00640 ^@ http://purl.uniprot.org/uniprot/B2A3T9 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/457570:NTHER_RS01245 ^@ http://purl.uniprot.org/uniprot/B2A4Q1 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/457570:NTHER_RS00090 ^@ http://purl.uniprot.org/uniprot/B2A2Z8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/457570:NTHER_RS04925 ^@ http://purl.uniprot.org/uniprot/B2A0I5 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/457570:NTHER_RS00310 ^@ http://purl.uniprot.org/uniprot/B2A3M5 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/457570:NTHER_RS02315 ^@ http://purl.uniprot.org/uniprot/B2A5T8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS00230 ^@ http://purl.uniprot.org/uniprot/B2A323 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS02565 ^@ http://purl.uniprot.org/uniprot/B2A668 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/457570:NTHER_RS01185 ^@ http://purl.uniprot.org/uniprot/B2A4F7 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/457570:NTHER_RS05835 ^@ http://purl.uniprot.org/uniprot/B2A168 ^@ Similarity ^@ Belongs to the UPF0236 family. http://togogenome.org/gene/457570:NTHER_RS00205 ^@ http://purl.uniprot.org/uniprot/B2A318 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/457570:NTHER_RS09365 ^@ http://purl.uniprot.org/uniprot/B2A608 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS08935 ^@ http://purl.uniprot.org/uniprot/B2A5I6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS16005 ^@ http://purl.uniprot.org/uniprot/B2A2D8 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. LacC subfamily.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/457570:NTHER_RS01545 ^@ http://purl.uniprot.org/uniprot/B2A4V8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/457570:NTHER_RS14605 ^@ http://purl.uniprot.org/uniprot/B2A3L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS09685 ^@ http://purl.uniprot.org/uniprot/B2A663 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS06460 ^@ http://purl.uniprot.org/uniprot/B2A252 ^@ Function|||Similarity ^@ Belongs to the BshC family.|||Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH. http://togogenome.org/gene/457570:NTHER_RS06545 ^@ http://purl.uniprot.org/uniprot/B2A2F9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS07000 ^@ http://purl.uniprot.org/uniprot/B2A335 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/457570:NTHER_RS08655 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS14510 ^@ http://purl.uniprot.org/uniprot/B2A3J4 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/457570:NTHER_RS11100 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS15440 ^@ http://purl.uniprot.org/uniprot/B2A1U0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS09610 ^@ http://purl.uniprot.org/uniprot/B2A652 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS05015 ^@ http://purl.uniprot.org/uniprot/B2A0K2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PstS family.|||Cell membrane|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Membrane|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/457570:NTHER_RS09545 ^@ http://purl.uniprot.org/uniprot/B2A640 ^@ Similarity ^@ Belongs to the radical SAM superfamily. KamA family. http://togogenome.org/gene/457570:NTHER_RS09775 ^@ http://purl.uniprot.org/uniprot/B2A6G7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS14010 ^@ http://purl.uniprot.org/uniprot/B2A2V8 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/457570:NTHER_RS05400 ^@ http://purl.uniprot.org/uniprot/B2A0U4 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/457570:NTHER_RS11930 ^@ http://purl.uniprot.org/uniprot/B2A8M8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS11355 ^@ http://purl.uniprot.org/uniprot/B2A833 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/457570:NTHER_RS01025 ^@ http://purl.uniprot.org/uniprot/B2A4C5 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/457570:NTHER_RS02900 ^@ http://purl.uniprot.org/uniprot/B2A6D5 ^@ Similarity ^@ Belongs to the pyruvate kinase family.|||In the C-terminal section; belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/457570:NTHER_RS14030 ^@ http://purl.uniprot.org/uniprot/B2A2W2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LPG synthase family.|||Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS09960 ^@ http://purl.uniprot.org/uniprot/B2A6J5 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/457570:NTHER_RS09925 ^@ http://purl.uniprot.org/uniprot/B2A6I8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/457570:NTHER_RS13325 ^@ http://purl.uniprot.org/uniprot/B2A0V7 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/457570:NTHER_RS02755 ^@ http://purl.uniprot.org/uniprot/B2A6A7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/457570:NTHER_RS13755 ^@ http://purl.uniprot.org/uniprot/B2A2Q9 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/457570:NTHER_RS02600 ^@ http://purl.uniprot.org/uniprot/B2A675 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/457570:NTHER_RS11360 ^@ http://purl.uniprot.org/uniprot/B2A834 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/457570:NTHER_RS04390 ^@ http://purl.uniprot.org/uniprot/B2A873 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS00080 ^@ http://purl.uniprot.org/uniprot/B2A2Z6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS02260 ^@ http://purl.uniprot.org/uniprot/B2A5S7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS07110 ^@ http://purl.uniprot.org/uniprot/B2A357 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/457570:NTHER_RS00005 ^@ http://purl.uniprot.org/uniprot/B2A2Y6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/457570:NTHER_RS02625 ^@ http://purl.uniprot.org/uniprot/B2A680 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS12380 ^@ http://purl.uniprot.org/uniprot/B2A168 ^@ Similarity ^@ Belongs to the UPF0236 family. http://togogenome.org/gene/457570:NTHER_RS08990 ^@ http://purl.uniprot.org/uniprot/B2A5J7 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS01330 ^@ http://purl.uniprot.org/uniprot/B2A4R7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/457570:NTHER_RS13630 ^@ http://purl.uniprot.org/uniprot/B2A2E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS03235 ^@ http://purl.uniprot.org/uniprot/B2A6T1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS01840 ^@ http://purl.uniprot.org/uniprot/B2A5A0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS12055 ^@ http://purl.uniprot.org/uniprot/B2A0R1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS01180 ^@ http://purl.uniprot.org/uniprot/B2A4F6 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/457570:NTHER_RS09620 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS08870 ^@ http://purl.uniprot.org/uniprot/B2A5H3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS05855 ^@ http://purl.uniprot.org/uniprot/B2A1J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS04770 ^@ http://purl.uniprot.org/uniprot/B2A0F4 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/457570:NTHER_RS09845 ^@ http://purl.uniprot.org/uniprot/B2A0V7 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/457570:NTHER_RS00775 ^@ http://purl.uniprot.org/uniprot/B2A482 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/457570:NTHER_RS12365 ^@ http://purl.uniprot.org/uniprot/B2A0X4 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/457570:NTHER_RS12095 ^@ http://purl.uniprot.org/uniprot/B2A0R9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS11935 ^@ http://purl.uniprot.org/uniprot/B2A0N7 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/457570:NTHER_RS11395 ^@ http://purl.uniprot.org/uniprot/B2A0U4 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/457570:NTHER_RS07995 ^@ http://purl.uniprot.org/uniprot/B2A4I1 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/457570:NTHER_RS14345 ^@ http://purl.uniprot.org/uniprot/B2A3G2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/457570:NTHER_RS13150 ^@ http://purl.uniprot.org/uniprot/B2A1W3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/457570:NTHER_RS01890 ^@ http://purl.uniprot.org/uniprot/B2A5B0 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/457570:NTHER_RS10590 ^@ http://purl.uniprot.org/uniprot/B2A755 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS07025 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS12450 ^@ http://purl.uniprot.org/uniprot/B2A182 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/457570:NTHER_RS08550 ^@ http://purl.uniprot.org/uniprot/B2A525 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/457570:NTHER_RS04805 ^@ http://purl.uniprot.org/uniprot/B2A0G1 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/457570:NTHER_RS04820 ^@ http://purl.uniprot.org/uniprot/B2A0G4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Membrane http://togogenome.org/gene/457570:NTHER_RS09325 ^@ http://purl.uniprot.org/uniprot/B2A600 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/457570:NTHER_RS13475 ^@ http://purl.uniprot.org/uniprot/B2A2B8 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/457570:NTHER_RS07200 ^@ http://purl.uniprot.org/uniprot/B2A375 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/457570:NTHER_RS09270 ^@ http://purl.uniprot.org/uniprot/B2A5Y9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS14295 ^@ http://purl.uniprot.org/uniprot/B2A3F2 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/457570:NTHER_RS04035 ^@ http://purl.uniprot.org/uniprot/B2A7R5 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M38 family.|||Binds 2 Zn(2+) ions per subunit.|||Carboxylation allows a single lysine to coordinate two zinc ions.|||Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS11110 ^@ http://purl.uniprot.org/uniprot/B2A7Y0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS03170 ^@ http://purl.uniprot.org/uniprot/B2A6R6 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/457570:NTHER_RS09395 ^@ http://purl.uniprot.org/uniprot/B2A615 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS02710 ^@ http://purl.uniprot.org/uniprot/B2A698 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/457570:NTHER_RS00455 ^@ http://purl.uniprot.org/uniprot/B2A3Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS03600 ^@ http://purl.uniprot.org/uniprot/B2A790 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS12810 ^@ http://purl.uniprot.org/uniprot/B2A1P6 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/457570:NTHER_RS00715 ^@ http://purl.uniprot.org/uniprot/B2A3U8 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/457570:NTHER_RS02730 ^@ http://purl.uniprot.org/uniprot/B2A6A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS12435 ^@ http://purl.uniprot.org/uniprot/B2A179 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily. http://togogenome.org/gene/457570:NTHER_RS03190 ^@ http://purl.uniprot.org/uniprot/B2A6S2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS02935 ^@ http://purl.uniprot.org/uniprot/B2A6E2 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/457570:NTHER_RS12160 ^@ http://purl.uniprot.org/uniprot/B2A0T2 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/457570:NTHER_RS02130 ^@ http://purl.uniprot.org/uniprot/B2A5P5 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/457570:NTHER_RS05790 ^@ http://purl.uniprot.org/uniprot/B2A1I6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/457570:NTHER_RS11340 ^@ http://purl.uniprot.org/uniprot/B2A826 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/457570:NTHER_RS03410 ^@ http://purl.uniprot.org/uniprot/B2A6W5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS09070 ^@ http://purl.uniprot.org/uniprot/B2A5L6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/457570:NTHER_RS02660 ^@ http://purl.uniprot.org/uniprot/B2A687 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS00305 ^@ http://purl.uniprot.org/uniprot/B2A3M4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/457570:NTHER_RS05970 ^@ http://purl.uniprot.org/uniprot/B2A1M6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/457570:NTHER_RS12360 ^@ http://purl.uniprot.org/uniprot/B2A0X3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS09110 ^@ http://purl.uniprot.org/uniprot/B2A5M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0291 family.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS07610 ^@ http://purl.uniprot.org/uniprot/B2A3Y4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/457570:NTHER_RS08345 ^@ http://purl.uniprot.org/uniprot/B2A4Y4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpA family.|||Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Cytoplasm|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/457570:NTHER_RS07330 ^@ http://purl.uniprot.org/uniprot/B2A3A1 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/457570:NTHER_RS06985 ^@ http://purl.uniprot.org/uniprot/B2A332 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/457570:NTHER_RS02420 ^@ http://purl.uniprot.org/uniprot/B2A5V9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS02835 ^@ http://purl.uniprot.org/uniprot/B2A6C3 ^@ Cofactor ^@ Binds 4 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/457570:NTHER_RS03400 ^@ http://purl.uniprot.org/uniprot/B2A6W3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS14360 ^@ http://purl.uniprot.org/uniprot/B2A3G5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/457570:NTHER_RS12490 ^@ http://purl.uniprot.org/uniprot/B2A190 ^@ Cofactor|||Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Binds 1 FAD per subunit.|||Binds 1 FMN covalently per subunit. http://togogenome.org/gene/457570:NTHER_RS05885 ^@ http://purl.uniprot.org/uniprot/B2A1K6 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/457570:NTHER_RS13395 ^@ http://purl.uniprot.org/uniprot/B2A2A2 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/457570:NTHER_RS13885 ^@ http://purl.uniprot.org/uniprot/B2A2T3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/457570:NTHER_RS12470 ^@ http://purl.uniprot.org/uniprot/B2A186 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/457570:NTHER_RS03765 ^@ http://purl.uniprot.org/uniprot/B2A7C2 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/457570:NTHER_RS01725 ^@ http://purl.uniprot.org/uniprot/B2A578 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS04735 ^@ http://purl.uniprot.org/uniprot/B2A8E4 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS03610 ^@ http://purl.uniprot.org/uniprot/B2A792 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/457570:NTHER_RS06095 ^@ http://purl.uniprot.org/uniprot/B2A1Y4 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/457570:NTHER_RS06590 ^@ http://purl.uniprot.org/uniprot/B2A2G9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS10005 ^@ http://purl.uniprot.org/uniprot/B2A6K4 ^@ Similarity ^@ Belongs to the peptidase S9A family. http://togogenome.org/gene/457570:NTHER_RS02685 ^@ http://purl.uniprot.org/uniprot/B2A693 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS01115 ^@ http://purl.uniprot.org/uniprot/B2A4E3 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/457570:NTHER_RS08215 ^@ http://purl.uniprot.org/uniprot/B2A4M5 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/457570:NTHER_RS08425 ^@ http://purl.uniprot.org/uniprot/B2A500 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/457570:NTHER_RS14515 ^@ http://purl.uniprot.org/uniprot/B2A3J5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/457570:NTHER_RS09385 ^@ http://purl.uniprot.org/uniprot/B2A612 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/457570:NTHER_RS00960 ^@ http://purl.uniprot.org/uniprot/B2A4B7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MrnC RNase family.|||Cytoplasm|||Homodimer.|||Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. http://togogenome.org/gene/457570:NTHER_RS14365 ^@ http://purl.uniprot.org/uniprot/B2A3G6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains. http://togogenome.org/gene/457570:NTHER_RS07225 ^@ http://purl.uniprot.org/uniprot/B2A380 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/457570:NTHER_RS12305 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS03300 ^@ http://purl.uniprot.org/uniprot/B2A6U3 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/457570:NTHER_RS09850 ^@ http://purl.uniprot.org/uniprot/B2A6I3 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/457570:NTHER_RS00735 ^@ http://purl.uniprot.org/uniprot/B2A3V3 ^@ Similarity ^@ Belongs to the ETF-QO/FixC family. http://togogenome.org/gene/457570:NTHER_RS02840 ^@ http://purl.uniprot.org/uniprot/B2A6C4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS05770 ^@ http://purl.uniprot.org/uniprot/B2A1I2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS02460 ^@ http://purl.uniprot.org/uniprot/B2A5W7 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/457570:NTHER_RS00315 ^@ http://purl.uniprot.org/uniprot/B2A3M6 ^@ Similarity ^@ Belongs to the NadC/ModD family. http://togogenome.org/gene/457570:NTHER_RS06950 ^@ http://purl.uniprot.org/uniprot/B2A2P3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/457570:NTHER_RS00195 ^@ http://purl.uniprot.org/uniprot/B2A316 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/457570:NTHER_RS11570 ^@ http://purl.uniprot.org/uniprot/B2A8G1 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/457570:NTHER_RS13415 ^@ http://purl.uniprot.org/uniprot/B2A2A6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS13830 ^@ http://purl.uniprot.org/uniprot/B2A2S2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS01035 ^@ http://purl.uniprot.org/uniprot/B2A4C7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/457570:NTHER_RS07570 ^@ http://purl.uniprot.org/uniprot/B2A3X7 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/457570:NTHER_RS05890 ^@ http://purl.uniprot.org/uniprot/B2A1K7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS03385 ^@ http://purl.uniprot.org/uniprot/B2A6W0 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/457570:NTHER_RS09770 ^@ http://purl.uniprot.org/uniprot/B2A6G6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS08585 ^@ http://purl.uniprot.org/uniprot/B2A532 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS09320 ^@ http://purl.uniprot.org/uniprot/B2A5Z9 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/457570:NTHER_RS02805 ^@ http://purl.uniprot.org/uniprot/B2A6B7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/457570:NTHER_RS02860 ^@ http://purl.uniprot.org/uniprot/B2A6C8 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/457570:NTHER_RS10260 ^@ http://purl.uniprot.org/uniprot/B2A6Z2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/457570:NTHER_RS14545 ^@ http://purl.uniprot.org/uniprot/B2A3K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS07565 ^@ http://purl.uniprot.org/uniprot/B2A3X6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/457570:NTHER_RS09495 ^@ http://purl.uniprot.org/uniprot/B2A631 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/457570:NTHER_RS05995 ^@ http://purl.uniprot.org/uniprot/B2A1N1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/457570:NTHER_RS00740 ^@ http://purl.uniprot.org/uniprot/B2A3V0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/457570:NTHER_RS09615 ^@ http://purl.uniprot.org/uniprot/B2A653 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/457570:NTHER_RS13295 ^@ http://purl.uniprot.org/uniprot/B2A168 ^@ Similarity ^@ Belongs to the UPF0236 family. http://togogenome.org/gene/457570:NTHER_RS11505 ^@ http://purl.uniprot.org/uniprot/B2A8E7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LPG synthase family.|||Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS04230 ^@ http://purl.uniprot.org/uniprot/B2A7V9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS00375 ^@ http://purl.uniprot.org/uniprot/B2A3N8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/457570:NTHER_RS10025 ^@ http://purl.uniprot.org/uniprot/B2A6K8 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/457570:NTHER_RS01205 ^@ http://purl.uniprot.org/uniprot/B2A4G3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/457570:NTHER_RS11755 ^@ http://purl.uniprot.org/uniprot/B2A8J8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS11955 ^@ http://purl.uniprot.org/uniprot/B2A0P0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/457570:NTHER_RS14500 ^@ http://purl.uniprot.org/uniprot/B2A3J2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/457570:NTHER_RS14520 ^@ http://purl.uniprot.org/uniprot/B2A3J6 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/457570:NTHER_RS08985 ^@ http://purl.uniprot.org/uniprot/B2A5J6 ^@ Similarity ^@ Belongs to the UPF0297 family. http://togogenome.org/gene/457570:NTHER_RS07105 ^@ http://purl.uniprot.org/uniprot/B2A356 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/457570:NTHER_RS08825 ^@ http://purl.uniprot.org/uniprot/B2A5G6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS04915 ^@ http://purl.uniprot.org/uniprot/B2A0I3 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/457570:NTHER_RS05545 ^@ http://purl.uniprot.org/uniprot/B2A155 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/457570:NTHER_RS04170 ^@ http://purl.uniprot.org/uniprot/B2A7U7 ^@ Similarity ^@ Belongs to the peptidase S24 family. http://togogenome.org/gene/457570:NTHER_RS08355 ^@ http://purl.uniprot.org/uniprot/B2A4Y6 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/457570:NTHER_RS08540 ^@ http://purl.uniprot.org/uniprot/B2A523 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/457570:NTHER_RS01600 ^@ http://purl.uniprot.org/uniprot/B2A4W9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/457570:NTHER_RS13485 ^@ http://purl.uniprot.org/uniprot/B2A2C0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS08745 ^@ http://purl.uniprot.org/uniprot/B2A563 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/457570:NTHER_RS00710 ^@ http://purl.uniprot.org/uniprot/B2A3U7 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/457570:NTHER_RS01755 ^@ http://purl.uniprot.org/uniprot/B2A583 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/457570:NTHER_RS10970 ^@ http://purl.uniprot.org/uniprot/B2A7L5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/457570:NTHER_RS11845 ^@ http://purl.uniprot.org/uniprot/B2A8L6 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/457570:NTHER_RS09785 ^@ http://purl.uniprot.org/uniprot/B2A6G9 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS13610 ^@ http://purl.uniprot.org/uniprot/B2A2E4 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/457570:NTHER_RS00750 ^@ http://purl.uniprot.org/uniprot/B2A477 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/457570:NTHER_RS06600 ^@ http://purl.uniprot.org/uniprot/B2A2H1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS06455 ^@ http://purl.uniprot.org/uniprot/B2A251 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS03510 ^@ http://purl.uniprot.org/uniprot/B2A772 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/457570:NTHER_RS15260 ^@ http://purl.uniprot.org/uniprot/B2A647 ^@ Similarity ^@ Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family. http://togogenome.org/gene/457570:NTHER_RS07985 ^@ http://purl.uniprot.org/uniprot/B2A4H9 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/457570:NTHER_RS02920 ^@ http://purl.uniprot.org/uniprot/B2A6D9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/457570:NTHER_RS14425 ^@ http://purl.uniprot.org/uniprot/B2A3H7 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/457570:NTHER_RS15355 ^@ http://purl.uniprot.org/uniprot/B2A8H8 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/457570:NTHER_RS05035 ^@ http://purl.uniprot.org/uniprot/B2A0K6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/457570:NTHER_RS09300 ^@ http://purl.uniprot.org/uniprot/B2A5Z5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS13950 ^@ http://purl.uniprot.org/uniprot/B2A2U6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/457570:NTHER_RS02905 ^@ http://purl.uniprot.org/uniprot/B2A6D6 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/457570:NTHER_RS08815 ^@ http://purl.uniprot.org/uniprot/B2A5G4 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/457570:NTHER_RS11775 ^@ http://purl.uniprot.org/uniprot/B2A8K2 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/457570:NTHER_RS14580 ^@ http://purl.uniprot.org/uniprot/B2A3K8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/457570:NTHER_RS14705 ^@ http://purl.uniprot.org/uniprot/B2A451 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/457570:NTHER_RS11830 ^@ http://purl.uniprot.org/uniprot/B2A8L3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/457570:NTHER_RS01195 ^@ http://purl.uniprot.org/uniprot/B2A4F9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/457570:NTHER_RS09485 ^@ http://purl.uniprot.org/uniprot/B2A629 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. http://togogenome.org/gene/457570:NTHER_RS06495 ^@ http://purl.uniprot.org/uniprot/B2A259 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS04545 ^@ http://purl.uniprot.org/uniprot/B2A8A5 ^@ Similarity ^@ Belongs to the pyruvoyl-dependent arginine decarboxylase family. http://togogenome.org/gene/457570:NTHER_RS02690 ^@ http://purl.uniprot.org/uniprot/B2A694 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.|||Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS09500 ^@ http://purl.uniprot.org/uniprot/B2A632 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/457570:NTHER_RS05510 ^@ http://purl.uniprot.org/uniprot/B2A147 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS02865 ^@ http://purl.uniprot.org/uniprot/B2A6C9 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/457570:NTHER_RS13335 ^@ http://purl.uniprot.org/uniprot/B2A291 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS09520 ^@ http://purl.uniprot.org/uniprot/B2A636 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/457570:NTHER_RS07195 ^@ http://purl.uniprot.org/uniprot/B2A374 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/457570:NTHER_RS08405 ^@ http://purl.uniprot.org/uniprot/B2A4Z6 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/457570:NTHER_RS13745 ^@ http://purl.uniprot.org/uniprot/B2A2Q7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS07380 ^@ http://purl.uniprot.org/uniprot/B2A3B1 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/457570:NTHER_RS09825 ^@ http://purl.uniprot.org/uniprot/B2A6H7 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/457570:NTHER_RS14405 ^@ http://purl.uniprot.org/uniprot/B2A3H3 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/457570:NTHER_RS09090 ^@ http://purl.uniprot.org/uniprot/B2A5M0 ^@ Similarity|||Subunit ^@ Belongs to the beta-eliminating lyase family.|||Homotetramer. http://togogenome.org/gene/457570:NTHER_RS12735 ^@ http://purl.uniprot.org/uniprot/B2A1E1 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/457570:NTHER_RS14560 ^@ http://purl.uniprot.org/uniprot/B2A3K4 ^@ Similarity ^@ Belongs to the radical SAM superfamily. KamA family. http://togogenome.org/gene/457570:NTHER_RS12190 ^@ http://purl.uniprot.org/uniprot/B2A0T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS14420 ^@ http://purl.uniprot.org/uniprot/B2A3H6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS08570 ^@ http://purl.uniprot.org/uniprot/B2A529 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/457570:NTHER_RS09935 ^@ http://purl.uniprot.org/uniprot/B2A6J0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS10165 ^@ http://purl.uniprot.org/uniprot/B2A6X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS07310 ^@ http://purl.uniprot.org/uniprot/B2A397 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/457570:NTHER_RS14185 ^@ http://purl.uniprot.org/uniprot/B2A3D0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/457570:NTHER_RS02605 ^@ http://purl.uniprot.org/uniprot/B2A676 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS07600 ^@ http://purl.uniprot.org/uniprot/B2A3Y2 ^@ Similarity ^@ Belongs to the CbxX/CfxQ family. http://togogenome.org/gene/457570:NTHER_RS15435 ^@ http://purl.uniprot.org/uniprot/B2A1T9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS00765 ^@ http://purl.uniprot.org/uniprot/B2A480 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS09510 ^@ http://purl.uniprot.org/uniprot/B2A634 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/457570:NTHER_RS09670 ^@ http://purl.uniprot.org/uniprot/B2A660 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/457570:NTHER_RS08285 ^@ http://purl.uniprot.org/uniprot/B2A4N9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS01350 ^@ http://purl.uniprot.org/uniprot/B2A4S1 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS12985 ^@ http://purl.uniprot.org/uniprot/B2A1T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS09035 ^@ http://purl.uniprot.org/uniprot/B2A5K8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/457570:NTHER_RS02795 ^@ http://purl.uniprot.org/uniprot/B2A6B5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/457570:NTHER_RS07270 ^@ http://purl.uniprot.org/uniprot/B2A389 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS06140 ^@ http://purl.uniprot.org/uniprot/B2A1Z3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/457570:NTHER_RS09155 ^@ http://purl.uniprot.org/uniprot/B2A5N0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell membrane|||Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS13890 ^@ http://purl.uniprot.org/uniprot/B2A2T4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/457570:NTHER_RS08415 ^@ http://purl.uniprot.org/uniprot/B2A4Z8 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/457570:NTHER_RS07295 ^@ http://purl.uniprot.org/uniprot/B2A394 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/457570:NTHER_RS14730 ^@ http://purl.uniprot.org/uniprot/B2A456 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/457570:NTHER_RS01070 ^@ http://purl.uniprot.org/uniprot/B2A4D4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/457570:NTHER_RS00685 ^@ http://purl.uniprot.org/uniprot/B2A3U2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/457570:NTHER_RS10170 ^@ http://purl.uniprot.org/uniprot/B2A6X2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/457570:NTHER_RS06980 ^@ http://purl.uniprot.org/uniprot/B2A331 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/457570:NTHER_RS08495 ^@ http://purl.uniprot.org/uniprot/B2A514 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/457570:NTHER_RS00265 ^@ http://purl.uniprot.org/uniprot/B2A307 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS01155 ^@ http://purl.uniprot.org/uniprot/B2A4F1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/457570:NTHER_RS05495 ^@ http://purl.uniprot.org/uniprot/B2A144 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS06330 ^@ http://purl.uniprot.org/uniprot/B2A226 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/457570:NTHER_RS13100 ^@ http://purl.uniprot.org/uniprot/B2A1V3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS06920 ^@ http://purl.uniprot.org/uniprot/B2A2N5 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/457570:NTHER_RS02080 ^@ http://purl.uniprot.org/uniprot/B2A5E8 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/457570:NTHER_RS00690 ^@ http://purl.uniprot.org/uniprot/B2A3U3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS04340 ^@ http://purl.uniprot.org/uniprot/B2A863 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/457570:NTHER_RS14355 ^@ http://purl.uniprot.org/uniprot/B2A3G4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/457570:NTHER_RS02785 ^@ http://purl.uniprot.org/uniprot/B2A6B3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/457570:NTHER_RS10035 ^@ http://purl.uniprot.org/uniprot/B2A6L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS15430 ^@ http://purl.uniprot.org/uniprot/B2A1T0 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/457570:NTHER_RS10325 ^@ http://purl.uniprot.org/uniprot/B2A705 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/457570:NTHER_RS11510 ^@ http://purl.uniprot.org/uniprot/B2A8E8 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/457570:NTHER_RS05025 ^@ http://purl.uniprot.org/uniprot/B2A0K4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/457570:NTHER_RS07315 ^@ http://purl.uniprot.org/uniprot/B2A398 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/457570:NTHER_RS00680 ^@ http://purl.uniprot.org/uniprot/B2A3U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS12385 ^@ http://purl.uniprot.org/uniprot/B2A169 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/457570:NTHER_RS10695 ^@ http://purl.uniprot.org/uniprot/B2A7G1 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/457570:NTHER_RS06450 ^@ http://purl.uniprot.org/uniprot/B2A250 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.|||Homodimer.|||Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate. http://togogenome.org/gene/457570:NTHER_RS07145 ^@ http://purl.uniprot.org/uniprot/B2A364 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/457570:NTHER_RS14380 ^@ http://purl.uniprot.org/uniprot/B2A3G9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/457570:NTHER_RS14810 ^@ http://purl.uniprot.org/uniprot/B2A472 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS09790 ^@ http://purl.uniprot.org/uniprot/B2A6H0 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/457570:NTHER_RS12510 ^@ http://purl.uniprot.org/uniprot/B2A195 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/457570:NTHER_RS07045 ^@ http://purl.uniprot.org/uniprot/B2A343 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/457570:NTHER_RS08890 ^@ http://purl.uniprot.org/uniprot/B2A5H7 ^@ Similarity ^@ Belongs to the thymidine kinase family. http://togogenome.org/gene/457570:NTHER_RS14555 ^@ http://purl.uniprot.org/uniprot/B2A3K3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell membrane|||Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS05050 ^@ http://purl.uniprot.org/uniprot/B2A0L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS11840 ^@ http://purl.uniprot.org/uniprot/B2A8L5 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/457570:NTHER_RS07355 ^@ http://purl.uniprot.org/uniprot/B2A3A6 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/457570:NTHER_RS13915 ^@ http://purl.uniprot.org/uniprot/B2A2T9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS06945 ^@ http://purl.uniprot.org/uniprot/B2A2P2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/457570:NTHER_RS05220 ^@ http://purl.uniprot.org/uniprot/B2A0Y3 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/457570:NTHER_RS08350 ^@ http://purl.uniprot.org/uniprot/B2A4Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS09245 ^@ http://purl.uniprot.org/uniprot/B2A5Y4 ^@ Similarity ^@ Belongs to the GbsR family. http://togogenome.org/gene/457570:NTHER_RS06640 ^@ http://purl.uniprot.org/uniprot/B2A2H9 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/457570:NTHER_RS08980 ^@ http://purl.uniprot.org/uniprot/B2A5J5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF nuclease family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS04350 ^@ http://purl.uniprot.org/uniprot/B2A865 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA (By similarity).|||Cytoplasm|||In the C-terminal section; belongs to the AccA family.|||In the N-terminal section; belongs to the AccD/PCCB family. http://togogenome.org/gene/457570:NTHER_RS10335 ^@ http://purl.uniprot.org/uniprot/B2A707 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/457570:NTHER_RS05490 ^@ http://purl.uniprot.org/uniprot/B2A143 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS13545 ^@ http://purl.uniprot.org/uniprot/B2A2D2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/457570:NTHER_RS12640 ^@ http://purl.uniprot.org/uniprot/B2A1C2 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/457570:NTHER_RS01085 ^@ http://purl.uniprot.org/uniprot/B2A4C2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/457570:NTHER_RS12165 ^@ http://purl.uniprot.org/uniprot/B2A0T3 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/457570:NTHER_RS10770 ^@ http://purl.uniprot.org/uniprot/B2A7H6 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/457570:NTHER_RS06885 ^@ http://purl.uniprot.org/uniprot/B2A2M8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/457570:NTHER_RS15200 ^@ http://purl.uniprot.org/uniprot/B2A2F5 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/457570:NTHER_RS02720 ^@ http://purl.uniprot.org/uniprot/B2A6A0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/457570:NTHER_RS13960 ^@ http://purl.uniprot.org/uniprot/B2A2U8 ^@ Function|||Similarity|||Subunit ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Homodimer and homohexamer; in equilibrium.|||Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. http://togogenome.org/gene/457570:NTHER_RS08740 ^@ http://purl.uniprot.org/uniprot/B2A562 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS01160 ^@ http://purl.uniprot.org/uniprot/B2A4F2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/457570:NTHER_RS00855 ^@ http://purl.uniprot.org/uniprot/B2A497 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/457570:NTHER_RS01220 ^@ http://purl.uniprot.org/uniprot/B2A4G1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/457570:NTHER_RS00280 ^@ http://purl.uniprot.org/uniprot/B2A3L9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/457570:NTHER_RS12060 ^@ http://purl.uniprot.org/uniprot/B2A0R2 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/457570:NTHER_RS00865 ^@ http://purl.uniprot.org/uniprot/B2A499 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/457570:NTHER_RS01055 ^@ http://purl.uniprot.org/uniprot/B2A4D1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/457570:NTHER_RS08695 ^@ http://purl.uniprot.org/uniprot/B2A553 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/457570:NTHER_RS05475 ^@ http://purl.uniprot.org/uniprot/B2A140 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/457570:NTHER_RS08555 ^@ http://purl.uniprot.org/uniprot/B2A526 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS06925 ^@ http://purl.uniprot.org/uniprot/B2A2N6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/457570:NTHER_RS13385 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS14145 ^@ http://purl.uniprot.org/uniprot/B2A2Y3 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/457570:NTHER_RS13380 ^@ http://purl.uniprot.org/uniprot/B2A2A0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS07175 ^@ http://purl.uniprot.org/uniprot/B2A370 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/457570:NTHER_RS07040 ^@ http://purl.uniprot.org/uniprot/B2A342 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/457570:NTHER_RS00805 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS10815 ^@ http://purl.uniprot.org/uniprot/B2A7I5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS12040 ^@ http://purl.uniprot.org/uniprot/B2A0Q8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/457570:NTHER_RS09200 ^@ http://purl.uniprot.org/uniprot/B2A5N9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/457570:NTHER_RS09840 ^@ http://purl.uniprot.org/uniprot/B2A6I1 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/457570:NTHER_RS06210 ^@ http://purl.uniprot.org/uniprot/B2A203 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/457570:NTHER_RS06485 ^@ http://purl.uniprot.org/uniprot/B2A257 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/457570:NTHER_RS08235 ^@ http://purl.uniprot.org/uniprot/B2A4M9 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/457570:NTHER_RS07265 ^@ http://purl.uniprot.org/uniprot/B2A388 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS04490 ^@ http://purl.uniprot.org/uniprot/B2A894 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/457570:NTHER_RS10040 ^@ http://purl.uniprot.org/uniprot/B2A6L1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS06670 ^@ http://purl.uniprot.org/uniprot/B2A2I5 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/457570:NTHER_RS12240 ^@ http://purl.uniprot.org/uniprot/B2A0U8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS06870 ^@ http://purl.uniprot.org/uniprot/B2A2M5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/457570:NTHER_RS09765 ^@ http://purl.uniprot.org/uniprot/B2A6G5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS03185 ^@ http://purl.uniprot.org/uniprot/B2A6S1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.|||Cell membrane|||Membrane|||Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. http://togogenome.org/gene/457570:NTHER_RS13440 ^@ http://purl.uniprot.org/uniprot/B2A2B1 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/457570:NTHER_RS05595 ^@ http://purl.uniprot.org/uniprot/B2A1E7 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/457570:NTHER_RS01260 ^@ http://purl.uniprot.org/uniprot/B2A4Q4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the energy-coupling factor EcfT family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).|||Membrane|||Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. http://togogenome.org/gene/457570:NTHER_RS06035 ^@ http://purl.uniprot.org/uniprot/B2A1P0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the flotillin-like FloA family.|||Cell membrane|||Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.|||Homooligomerizes.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane raft http://togogenome.org/gene/457570:NTHER_RS10285 ^@ http://purl.uniprot.org/uniprot/B2A6Z7 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/457570:NTHER_RS14415 ^@ http://purl.uniprot.org/uniprot/B2A3H5 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/457570:NTHER_RS02990 ^@ http://purl.uniprot.org/uniprot/B2A6N0 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. http://togogenome.org/gene/457570:NTHER_RS03900 ^@ http://purl.uniprot.org/uniprot/B2A7P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS08300 ^@ http://purl.uniprot.org/uniprot/B2A4P2 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/457570:NTHER_RS00250 ^@ http://purl.uniprot.org/uniprot/B2A327 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS00470 ^@ http://purl.uniprot.org/uniprot/B2A3Q6 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/457570:NTHER_RS05180 ^@ http://purl.uniprot.org/uniprot/B2A0X5 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/457570:NTHER_RS03450 ^@ http://purl.uniprot.org/uniprot/B2A761 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. SigI subfamily.|||Cytoplasm|||Interacts with RsgI.|||Negatively regulated by the anti-sigma-I factor RsgI.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/457570:NTHER_RS08810 ^@ http://purl.uniprot.org/uniprot/B2A5G3 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/457570:NTHER_RS11800 ^@ http://purl.uniprot.org/uniprot/B2A8K7 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/457570:NTHER_RS06580 ^@ http://purl.uniprot.org/uniprot/B2A2G7 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS11140 ^@ http://purl.uniprot.org/uniprot/B2A7Y5 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family. http://togogenome.org/gene/457570:NTHER_RS09580 ^@ http://purl.uniprot.org/uniprot/B2A646 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/457570:NTHER_RS00355 ^@ http://purl.uniprot.org/uniprot/B2A3N4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS14325 ^@ http://purl.uniprot.org/uniprot/B2A3F8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS00980 ^@ http://purl.uniprot.org/uniprot/B2A4C1 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival. http://togogenome.org/gene/457570:NTHER_RS14200 ^@ http://purl.uniprot.org/uniprot/B2A3D3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS04555 ^@ http://purl.uniprot.org/uniprot/B2A140 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/457570:NTHER_RS08760 ^@ http://purl.uniprot.org/uniprot/B2A567 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/457570:NTHER_RS09080 ^@ http://purl.uniprot.org/uniprot/B2A5L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS09575 ^@ http://purl.uniprot.org/uniprot/B2A645 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/457570:NTHER_RS06990 ^@ http://purl.uniprot.org/uniprot/B2A333 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/457570:NTHER_RS11405 ^@ http://purl.uniprot.org/uniprot/B2A843 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily. http://togogenome.org/gene/457570:NTHER_RS07810 ^@ http://purl.uniprot.org/uniprot/B2A422 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS07235 ^@ http://purl.uniprot.org/uniprot/B2A382 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS11915 ^@ http://purl.uniprot.org/uniprot/B2A8N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS12250 ^@ http://purl.uniprot.org/uniprot/B2A0V0 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/457570:NTHER_RS02390 ^@ http://purl.uniprot.org/uniprot/B2A5V3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/457570:NTHER_RS13850 ^@ http://purl.uniprot.org/uniprot/B2A2S6 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/457570:NTHER_RS06740 ^@ http://purl.uniprot.org/uniprot/B2A2J9 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS14410 ^@ http://purl.uniprot.org/uniprot/B2A3H4 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/457570:NTHER_RS01270 ^@ http://purl.uniprot.org/uniprot/B2A4Q6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/457570:NTHER_RS14485 ^@ http://purl.uniprot.org/uniprot/B2A3I9 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/457570:NTHER_RS10560 ^@ http://purl.uniprot.org/uniprot/B2A749 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS15000 ^@ http://purl.uniprot.org/uniprot/B2A691 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS07575 ^@ http://purl.uniprot.org/uniprot/B2A3X8 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/457570:NTHER_RS10160 ^@ http://purl.uniprot.org/uniprot/B2A6X0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/457570:NTHER_RS04105 ^@ http://purl.uniprot.org/uniprot/B2A7T1 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/457570:NTHER_RS05085 ^@ http://purl.uniprot.org/uniprot/B2A0L7 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/457570:NTHER_RS14735 ^@ http://purl.uniprot.org/uniprot/B2A457 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/457570:NTHER_RS05950 ^@ http://purl.uniprot.org/uniprot/B2A1L9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/457570:NTHER_RS02985 ^@ http://purl.uniprot.org/uniprot/B2A6E8 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/457570:NTHER_RS07135 ^@ http://purl.uniprot.org/uniprot/B2A362 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/457570:NTHER_RS15215 ^@ http://purl.uniprot.org/uniprot/B2A353 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/457570:NTHER_RS07335 ^@ http://purl.uniprot.org/uniprot/B2A3A2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/457570:NTHER_RS10230 ^@ http://purl.uniprot.org/uniprot/B2A6Y6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS11175 ^@ http://purl.uniprot.org/uniprot/B2A7Z2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS14480 ^@ http://purl.uniprot.org/uniprot/B2A3I8 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/457570:NTHER_RS13235 ^@ http://purl.uniprot.org/uniprot/B2A269 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS13940 ^@ http://purl.uniprot.org/uniprot/B2A2U4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.|||Cytoplasm|||Heterotetramer of 2 PyrK and 2 PyrD type B subunits. http://togogenome.org/gene/457570:NTHER_RS14250 ^@ http://purl.uniprot.org/uniprot/B2A3E3 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/457570:NTHER_RS04485 ^@ http://purl.uniprot.org/uniprot/B2A892 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/457570:NTHER_RS08950 ^@ http://purl.uniprot.org/uniprot/B2A5I9 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/457570:NTHER_RS10190 ^@ http://purl.uniprot.org/uniprot/B2A6X9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS06770 ^@ http://purl.uniprot.org/uniprot/B2A2K5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/457570:NTHER_RS06440 ^@ http://purl.uniprot.org/uniprot/B2A248 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/457570:NTHER_RS11245 ^@ http://purl.uniprot.org/uniprot/B2A806 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/457570:NTHER_RS11670 ^@ http://purl.uniprot.org/uniprot/B2A8I1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/457570:NTHER_RS00880 ^@ http://purl.uniprot.org/uniprot/B2A4A2 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/457570:NTHER_RS13625 ^@ http://purl.uniprot.org/uniprot/B2A2E7 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/457570:NTHER_RS12660 ^@ http://purl.uniprot.org/uniprot/B2A1C6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS05020 ^@ http://purl.uniprot.org/uniprot/B2A0K3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/457570:NTHER_RS01235 ^@ http://purl.uniprot.org/uniprot/B2A4P9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/457570:NTHER_RS07430 ^@ http://purl.uniprot.org/uniprot/B2A3C1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/457570:NTHER_RS03675 ^@ http://purl.uniprot.org/uniprot/B2A7A5 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/457570:NTHER_RS05090 ^@ http://purl.uniprot.org/uniprot/B2A0L8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/457570:NTHER_RS09060 ^@ http://purl.uniprot.org/uniprot/B2A5L4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/457570:NTHER_RS11960 ^@ http://purl.uniprot.org/uniprot/B2A0P2 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/457570:NTHER_RS11305 ^@ http://purl.uniprot.org/uniprot/B2A819 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/457570:NTHER_RS13515 ^@ http://purl.uniprot.org/uniprot/B2A2C6 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily. http://togogenome.org/gene/457570:NTHER_RS11325 ^@ http://purl.uniprot.org/uniprot/B2A823 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/457570:NTHER_RS13945 ^@ http://purl.uniprot.org/uniprot/B2A2U5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit.|||Heterotetramer of 2 PyrK and 2 PyrD type B subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). http://togogenome.org/gene/457570:NTHER_RS06685 ^@ http://purl.uniprot.org/uniprot/B2A2I8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/457570:NTHER_RS03395 ^@ http://purl.uniprot.org/uniprot/B2A6W2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS05040 ^@ http://purl.uniprot.org/uniprot/B2A0K7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS06105 ^@ http://purl.uniprot.org/uniprot/B2A1Y6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/457570:NTHER_RS07290 ^@ http://purl.uniprot.org/uniprot/B2A393 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/457570:NTHER_RS12220 ^@ http://purl.uniprot.org/uniprot/B2A0U4 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/457570:NTHER_RS05580 ^@ http://purl.uniprot.org/uniprot/B2A157 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/457570:NTHER_RS10185 ^@ http://purl.uniprot.org/uniprot/B2A6X8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.|||This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. http://togogenome.org/gene/457570:NTHER_RS07125 ^@ http://purl.uniprot.org/uniprot/B2A360 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS12005 ^@ http://purl.uniprot.org/uniprot/B2A0Q1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/457570:NTHER_RS01975 ^@ http://purl.uniprot.org/uniprot/B2A5C7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/457570:NTHER_RS12570 ^@ http://purl.uniprot.org/uniprot/B2A1A7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TenA family.|||Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.|||Homotetramer. http://togogenome.org/gene/457570:NTHER_RS00550 ^@ http://purl.uniprot.org/uniprot/B2A3S2 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/457570:NTHER_RS00450 ^@ http://purl.uniprot.org/uniprot/B2A3Q2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/457570:NTHER_RS08675 ^@ http://purl.uniprot.org/uniprot/B2A549 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/457570:NTHER_RS06125 ^@ http://purl.uniprot.org/uniprot/B2A1Z0 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/457570:NTHER_RS11560 ^@ http://purl.uniprot.org/uniprot/B2A8F9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/457570:NTHER_RS08435 ^@ http://purl.uniprot.org/uniprot/B2A502 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/457570:NTHER_RS02375 ^@ http://purl.uniprot.org/uniprot/B2A5V0 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/457570:NTHER_RS10855 ^@ http://purl.uniprot.org/uniprot/B2A7J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS04955 ^@ http://purl.uniprot.org/uniprot/B2A0J1 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/457570:NTHER_RS01340 ^@ http://purl.uniprot.org/uniprot/B2A4R9 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/457570:NTHER_RS01080 ^@ http://purl.uniprot.org/uniprot/B2A4D6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS02410 ^@ http://purl.uniprot.org/uniprot/B2A5V7 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/457570:NTHER_RS01045 ^@ http://purl.uniprot.org/uniprot/B2A4C9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/457570:NTHER_RS05765 ^@ http://purl.uniprot.org/uniprot/B2A1I1 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/457570:NTHER_RS07340 ^@ http://purl.uniprot.org/uniprot/B2A3A3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/457570:NTHER_RS03355 ^@ http://purl.uniprot.org/uniprot/B2A6V4 ^@ Function|||Similarity ^@ Belongs to the THEP1 NTPase family.|||Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency. http://togogenome.org/gene/457570:NTHER_RS10500 ^@ http://purl.uniprot.org/uniprot/B2A738 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/457570:NTHER_RS13740 ^@ http://purl.uniprot.org/uniprot/B2A2Q6 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the FBP aldolase/phosphatase family.|||Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).|||Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.|||Homooctamer; dimer of tetramers. http://togogenome.org/gene/457570:NTHER_RS11005 ^@ http://purl.uniprot.org/uniprot/B2A7M2 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/457570:NTHER_RS12325 ^@ http://purl.uniprot.org/uniprot/B2A0W4 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/457570:NTHER_RS12390 ^@ http://purl.uniprot.org/uniprot/B2A170 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/457570:NTHER_RS16270 ^@ http://purl.uniprot.org/uniprot/B2A6Z3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/457570:NTHER_RS09735 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS06325 ^@ http://purl.uniprot.org/uniprot/B2A225 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/457570:NTHER_RS08000 ^@ http://purl.uniprot.org/uniprot/B2A4I2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/457570:NTHER_RS12545 ^@ http://purl.uniprot.org/uniprot/B2A1A2 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/457570:NTHER_RS07260 ^@ http://purl.uniprot.org/uniprot/B2A387 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS10685 ^@ http://purl.uniprot.org/uniprot/B2A7F9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS08995 ^@ http://purl.uniprot.org/uniprot/B2A5J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS12395 ^@ http://purl.uniprot.org/uniprot/B2A171 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/457570:NTHER_RS02945 ^@ http://purl.uniprot.org/uniprot/B2A6E4 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/457570:NTHER_RS04190 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS03655 ^@ http://purl.uniprot.org/uniprot/B2A7A1 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/457570:NTHER_RS14400 ^@ http://purl.uniprot.org/uniprot/B2A3H2 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/457570:NTHER_RS00020 ^@ http://purl.uniprot.org/uniprot/B2A2Y9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/457570:NTHER_RS07530 ^@ http://purl.uniprot.org/uniprot/B2A3W9 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/457570:NTHER_RS08060 ^@ http://purl.uniprot.org/uniprot/B2A4J4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS09795 ^@ http://purl.uniprot.org/uniprot/B2A6H1 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/457570:NTHER_RS00420 ^@ http://purl.uniprot.org/uniprot/B2A3P7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsL family.|||Cell membrane|||Essential cell division protein.|||Membrane http://togogenome.org/gene/457570:NTHER_RS07100 ^@ http://purl.uniprot.org/uniprot/B2A355 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS00110 ^@ http://purl.uniprot.org/uniprot/B2A2Z9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS01655 ^@ http://purl.uniprot.org/uniprot/B2A4X6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/457570:NTHER_RS06020 ^@ http://purl.uniprot.org/uniprot/B2A1N7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/457570:NTHER_RS06900 ^@ http://purl.uniprot.org/uniprot/B2A2N1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS08150 ^@ http://purl.uniprot.org/uniprot/B2A4L0 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/457570:NTHER_RS13510 ^@ http://purl.uniprot.org/uniprot/B2A2C5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS14505 ^@ http://purl.uniprot.org/uniprot/B2A3J3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS05200 ^@ http://purl.uniprot.org/uniprot/B2A0X9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.|||Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS05785 ^@ http://purl.uniprot.org/uniprot/B2A1I5 ^@ Similarity ^@ Belongs to the D-glutamate cyclase family. http://togogenome.org/gene/457570:NTHER_RS09470 ^@ http://purl.uniprot.org/uniprot/B2A626 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/457570:NTHER_RS12200 ^@ http://purl.uniprot.org/uniprot/B2A0U0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/457570:NTHER_RS01550 ^@ http://purl.uniprot.org/uniprot/B2A4V9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/457570:NTHER_RS03490 ^@ http://purl.uniprot.org/uniprot/B2A768 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/457570:NTHER_RS14370 ^@ http://purl.uniprot.org/uniprot/B2A3G7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits. http://togogenome.org/gene/457570:NTHER_RS09190 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS12825 ^@ http://purl.uniprot.org/uniprot/B2A1P9 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/457570:NTHER_RS01690 ^@ http://purl.uniprot.org/uniprot/B2A571 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/457570:NTHER_RS10475 ^@ http://purl.uniprot.org/uniprot/B2A733 ^@ Similarity ^@ Belongs to the GbsR family. http://togogenome.org/gene/457570:NTHER_RS09680 ^@ http://purl.uniprot.org/uniprot/B2A0U4 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/457570:NTHER_RS10175 ^@ http://purl.uniprot.org/uniprot/B2A6X3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS09700 ^@ http://purl.uniprot.org/uniprot/B2A6F4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/457570:NTHER_RS11795 ^@ http://purl.uniprot.org/uniprot/B2A8K6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS00925 ^@ http://purl.uniprot.org/uniprot/B2A4B0 ^@ Similarity ^@ Belongs to the ycf81 family. http://togogenome.org/gene/457570:NTHER_RS09455 ^@ http://purl.uniprot.org/uniprot/B2A623 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/457570:NTHER_RS09380 ^@ http://purl.uniprot.org/uniprot/B2A611 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the helicase family. AddB/RexB type 1 subfamily.|||Binds 1 [4Fe-4S] cluster.|||Heterodimer of AddA and AddB.|||The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. http://togogenome.org/gene/457570:NTHER_RS13470 ^@ http://purl.uniprot.org/uniprot/B2A2B7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS05115 ^@ http://purl.uniprot.org/uniprot/B2A0M6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS07065 ^@ http://purl.uniprot.org/uniprot/B2A347 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS07425 ^@ http://purl.uniprot.org/uniprot/B2A3C0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS02630 ^@ http://purl.uniprot.org/uniprot/B2A681 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS04475 ^@ http://purl.uniprot.org/uniprot/B2A890 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/457570:NTHER_RS11370 ^@ http://purl.uniprot.org/uniprot/B2A836 ^@ Similarity ^@ Belongs to the FlgM family. http://togogenome.org/gene/457570:NTHER_RS05455 ^@ http://purl.uniprot.org/uniprot/B2A136 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/457570:NTHER_RS14080 ^@ http://purl.uniprot.org/uniprot/B2A2W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS12440 ^@ http://purl.uniprot.org/uniprot/B2A180 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/457570:NTHER_RS00135 ^@ http://purl.uniprot.org/uniprot/B2A302 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/457570:NTHER_RS12445 ^@ http://purl.uniprot.org/uniprot/B2A181 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/457570:NTHER_RS01190 ^@ http://purl.uniprot.org/uniprot/B2A4F8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/457570:NTHER_RS12575 ^@ http://purl.uniprot.org/uniprot/B2A1A8 ^@ Function|||Similarity ^@ Belongs to the Thz kinase family.|||Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). http://togogenome.org/gene/457570:NTHER_RS12830 ^@ http://purl.uniprot.org/uniprot/B2A1Q0 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/457570:NTHER_RS05600 ^@ http://purl.uniprot.org/uniprot/B2A1E8 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/457570:NTHER_RS03555 ^@ http://purl.uniprot.org/uniprot/B2A781 ^@ Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. http://togogenome.org/gene/457570:NTHER_RS14340 ^@ http://purl.uniprot.org/uniprot/B2A3G1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/457570:NTHER_RS06755 ^@ http://purl.uniprot.org/uniprot/B2A2K2 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/457570:NTHER_RS07550 ^@ http://purl.uniprot.org/uniprot/B2A3X3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS04640 ^@ http://purl.uniprot.org/uniprot/B2A8C4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Cell membrane|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Lacks the conserved Asp active site. http://togogenome.org/gene/457570:NTHER_RS08605 ^@ http://purl.uniprot.org/uniprot/B2A536 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/457570:NTHER_RS06135 ^@ http://purl.uniprot.org/uniprot/B2A1Z2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/457570:NTHER_RS03630 ^@ http://purl.uniprot.org/uniprot/B2A796 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS13600 ^@ http://purl.uniprot.org/uniprot/B2A2E2 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/457570:NTHER_RS08065 ^@ http://purl.uniprot.org/uniprot/B2A4J5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/457570:NTHER_RS11075 ^@ http://purl.uniprot.org/uniprot/B2A7X4 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/457570:NTHER_RS12125 ^@ http://purl.uniprot.org/uniprot/B2A0S5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS03345 ^@ http://purl.uniprot.org/uniprot/B2A6V2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily.|||Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS03565 ^@ http://purl.uniprot.org/uniprot/B2A783 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably interacts with PlsX. http://togogenome.org/gene/457570:NTHER_RS03980 ^@ http://purl.uniprot.org/uniprot/B2A7Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS06840 ^@ http://purl.uniprot.org/uniprot/B2A2L9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS05150 ^@ http://purl.uniprot.org/uniprot/B2A0N4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS02140 ^@ http://purl.uniprot.org/uniprot/B2A5P7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS09205 ^@ http://purl.uniprot.org/uniprot/B2A5P0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/457570:NTHER_RS06550 ^@ http://purl.uniprot.org/uniprot/B2A2G0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS05955 ^@ http://purl.uniprot.org/uniprot/B2A1M0 ^@ Function|||PTM|||Similarity|||Subunit ^@ Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.|||Belongs to the peptidase A25 family.|||Homotetramer.|||Initiates the rapid degradation of small, acid-soluble proteins during spore germination. http://togogenome.org/gene/457570:NTHER_RS00825 ^@ http://purl.uniprot.org/uniprot/B2A491 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/457570:NTHER_RS10280 ^@ http://purl.uniprot.org/uniprot/B2A6Z6 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/457570:NTHER_RS04385 ^@ http://purl.uniprot.org/uniprot/B2A872 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/457570:NTHER_RS14430 ^@ http://purl.uniprot.org/uniprot/B2A3H8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS11910 ^@ http://purl.uniprot.org/uniprot/B2A8M9 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/457570:NTHER_RS02480 ^@ http://purl.uniprot.org/uniprot/B2A5X1 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/457570:NTHER_RS13770 ^@ http://purl.uniprot.org/uniprot/B2A2R2 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/457570:NTHER_RS00930 ^@ http://purl.uniprot.org/uniprot/B2A4B1 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/457570:NTHER_RS01705 ^@ http://purl.uniprot.org/uniprot/B2A574 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/457570:NTHER_RS06850 ^@ http://purl.uniprot.org/uniprot/B2A2M1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcAL family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS12155 ^@ http://purl.uniprot.org/uniprot/B2A0T1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/457570:NTHER_RS01100 ^@ http://purl.uniprot.org/uniprot/B2A4E0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/457570:NTHER_RS06535 ^@ http://purl.uniprot.org/uniprot/B2A2F7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS05505 ^@ http://purl.uniprot.org/uniprot/B2A146 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS04345 ^@ http://purl.uniprot.org/uniprot/B2A864 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/457570:NTHER_RS09595 ^@ http://purl.uniprot.org/uniprot/B2A649 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/457570:NTHER_RS09550 ^@ http://purl.uniprot.org/uniprot/B2A641 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS01675 ^@ http://purl.uniprot.org/uniprot/B2A4Y0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS09215 ^@ http://purl.uniprot.org/uniprot/B2A5P2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS13420 ^@ http://purl.uniprot.org/uniprot/B2A2A7 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/457570:NTHER_RS10840 ^@ http://purl.uniprot.org/uniprot/B2A7I9 ^@ Cofactor|||Similarity ^@ Belongs to the UPF0313 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/457570:NTHER_RS02725 ^@ http://purl.uniprot.org/uniprot/B2A6A1 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/457570:NTHER_RS06635 ^@ http://purl.uniprot.org/uniprot/B2A2H8 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/457570:NTHER_RS08945 ^@ http://purl.uniprot.org/uniprot/B2A5I8 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/457570:NTHER_RS03455 ^@ http://purl.uniprot.org/uniprot/B2A762 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS01175 ^@ http://purl.uniprot.org/uniprot/B2A4F5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/457570:NTHER_RS02435 ^@ http://purl.uniprot.org/uniprot/B2A5W2 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/457570:NTHER_RS02415 ^@ http://purl.uniprot.org/uniprot/B2A5V8 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/457570:NTHER_RS10255 ^@ http://purl.uniprot.org/uniprot/B2A6Z1 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/457570:NTHER_RS10550 ^@ http://purl.uniprot.org/uniprot/B2A747 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C15 family.|||Cytoplasm|||Removes 5-oxoproline from various penultimate amino acid residues except L-proline. http://togogenome.org/gene/457570:NTHER_RS05010 ^@ http://purl.uniprot.org/uniprot/B2A0K1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS10130 ^@ http://purl.uniprot.org/uniprot/B2A6M8 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/457570:NTHER_RS03195 ^@ http://purl.uniprot.org/uniprot/B2A6S3 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/457570:NTHER_RS08775 ^@ http://purl.uniprot.org/uniprot/B2A566 ^@ Similarity ^@ Belongs to the sigma-70 factor family. http://togogenome.org/gene/457570:NTHER_RS02160 ^@ http://purl.uniprot.org/uniprot/B2A5Q1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS06185 ^@ http://purl.uniprot.org/uniprot/B2A1Z8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS07440 ^@ http://purl.uniprot.org/uniprot/B2A3C3 ^@ Similarity ^@ Belongs to the AAA ATPase family.|||In the C-terminal section; belongs to the peptidase M41 family. http://togogenome.org/gene/457570:NTHER_RS08885 ^@ http://purl.uniprot.org/uniprot/B2A5H6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. http://togogenome.org/gene/457570:NTHER_RS10300 ^@ http://purl.uniprot.org/uniprot/B2A700 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/457570:NTHER_RS02455 ^@ http://purl.uniprot.org/uniprot/B2A5W6 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/457570:NTHER_RS12345 ^@ http://purl.uniprot.org/uniprot/B2A0W8 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/457570:NTHER_RS08165 ^@ http://purl.uniprot.org/uniprot/B2A4L3 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/457570:NTHER_RS13505 ^@ http://purl.uniprot.org/uniprot/B2A2C4 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/457570:NTHER_RS07945 ^@ http://purl.uniprot.org/uniprot/B2A4H1 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS06515 ^@ http://purl.uniprot.org/uniprot/B2A263 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/457570:NTHER_RS10360 ^@ http://purl.uniprot.org/uniprot/B2A712 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/457570:NTHER_RS06130 ^@ http://purl.uniprot.org/uniprot/B2A1Z1 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/457570:NTHER_RS01230 ^@ http://purl.uniprot.org/uniprot/B2A4P8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/457570:NTHER_RS06880 ^@ http://purl.uniprot.org/uniprot/B2A2M7 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/457570:NTHER_RS00155 ^@ http://purl.uniprot.org/uniprot/B2A308 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/457570:NTHER_RS02830 ^@ http://purl.uniprot.org/uniprot/B2A6C2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS05965 ^@ http://purl.uniprot.org/uniprot/B2A1M2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/457570:NTHER_RS03245 ^@ http://purl.uniprot.org/uniprot/B2A6T3 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/457570:NTHER_RS06610 ^@ http://purl.uniprot.org/uniprot/B2A2H3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS06930 ^@ http://purl.uniprot.org/uniprot/B2A2N7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/457570:NTHER_RS02745 ^@ http://purl.uniprot.org/uniprot/B2A6A5 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/457570:NTHER_RS06345 ^@ http://purl.uniprot.org/uniprot/B2A229 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/457570:NTHER_RS05125 ^@ http://purl.uniprot.org/uniprot/B2A0M9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS02125 ^@ http://purl.uniprot.org/uniprot/B2A5P4 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/457570:NTHER_RS05675 ^@ http://purl.uniprot.org/uniprot/B2A1G2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS00940 ^@ http://purl.uniprot.org/uniprot/B2A4B3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/457570:NTHER_RS12460 ^@ http://purl.uniprot.org/uniprot/B2A184 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/457570:NTHER_RS11715 ^@ http://purl.uniprot.org/uniprot/B2A8J1 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/457570:NTHER_RS02155 ^@ http://purl.uniprot.org/uniprot/B2A5Q0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/457570:NTHER_RS07585 ^@ http://purl.uniprot.org/uniprot/B2A3Y0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/457570:NTHER_RS05935 ^@ http://purl.uniprot.org/uniprot/B2A1L6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS14540 ^@ http://purl.uniprot.org/uniprot/B2A3K0 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/457570:NTHER_RS01795 ^@ http://purl.uniprot.org/uniprot/B2A591 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS07160 ^@ http://purl.uniprot.org/uniprot/B2A367 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Cell membrane|||Membrane|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/457570:NTHER_RS09660 ^@ http://purl.uniprot.org/uniprot/B2A666 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/457570:NTHER_RS09370 ^@ http://purl.uniprot.org/uniprot/B2A609 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/457570:NTHER_RS12945 ^@ http://purl.uniprot.org/uniprot/B2A1S3 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/457570:NTHER_RS05690 ^@ http://purl.uniprot.org/uniprot/B2A1G5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS04865 ^@ http://purl.uniprot.org/uniprot/B2A0H3 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/457570:NTHER_RS13825 ^@ http://purl.uniprot.org/uniprot/B2A2S1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS04930 ^@ http://purl.uniprot.org/uniprot/B2A0I6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS04765 ^@ http://purl.uniprot.org/uniprot/B2A0F3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS13620 ^@ http://purl.uniprot.org/uniprot/B2A2E6 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/457570:NTHER_RS13210 ^@ http://purl.uniprot.org/uniprot/B2A1X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/457570:NTHER_RS00235 ^@ http://purl.uniprot.org/uniprot/B2A0U4 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/457570:NTHER_RS14190 ^@ http://purl.uniprot.org/uniprot/B2A3D1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS07915 ^@ http://purl.uniprot.org/uniprot/B2A4G5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS15190 ^@ http://purl.uniprot.org/uniprot/B2A1X9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/457570:NTHER_RS00595 ^@ http://purl.uniprot.org/uniprot/B2A3T0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.|||Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS04090 ^@ http://purl.uniprot.org/uniprot/B2A7S7 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/457570:NTHER_RS13570 ^@ http://purl.uniprot.org/uniprot/B2A2D7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbsD / FucU family. RbsD subfamily.|||Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.|||Cytoplasm|||Homodecamer. http://togogenome.org/gene/457570:NTHER_RS05130 ^@ http://purl.uniprot.org/uniprot/B2A0N0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M38 family.|||Binds 2 Zn(2+) ions per subunit.|||Carboxylation allows a single lysine to coordinate two zinc ions.|||Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS00935 ^@ http://purl.uniprot.org/uniprot/B2A4B2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/457570:NTHER_RS11320 ^@ http://purl.uniprot.org/uniprot/B2A822 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/457570:NTHER_RS11690 ^@ http://purl.uniprot.org/uniprot/B2A8I5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/457570:NTHER_RS01170 ^@ http://purl.uniprot.org/uniprot/B2A4F4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/457570:NTHER_RS08420 ^@ http://purl.uniprot.org/uniprot/B2A4Z9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/457570:NTHER_RS06090 ^@ http://purl.uniprot.org/uniprot/B2A1Y3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/457570:NTHER_RS02635 ^@ http://purl.uniprot.org/uniprot/B2A682 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS04885 ^@ http://purl.uniprot.org/uniprot/B2A0H6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS05585 ^@ http://purl.uniprot.org/uniprot/B2A158 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/457570:NTHER_RS10450 ^@ http://purl.uniprot.org/uniprot/B2A728 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/457570:NTHER_RS10290 ^@ http://purl.uniprot.org/uniprot/B2A6Z8 ^@ Similarity ^@ Belongs to the beta-eliminating lyase family. http://togogenome.org/gene/457570:NTHER_RS06080 ^@ http://purl.uniprot.org/uniprot/B2A1Y1 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/457570:NTHER_RS07410 ^@ http://purl.uniprot.org/uniprot/B2A3B7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS09030 ^@ http://purl.uniprot.org/uniprot/B2A5K7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS12150 ^@ http://purl.uniprot.org/uniprot/B2A0T0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/457570:NTHER_RS08120 ^@ http://purl.uniprot.org/uniprot/B2A4K5 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/457570:NTHER_RS11920 ^@ http://purl.uniprot.org/uniprot/B2A8N1 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/457570:NTHER_RS12400 ^@ http://purl.uniprot.org/uniprot/B2A172 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS06490 ^@ http://purl.uniprot.org/uniprot/B2A258 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/457570:NTHER_RS08070 ^@ http://purl.uniprot.org/uniprot/B2A4J6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS14075 ^@ http://purl.uniprot.org/uniprot/B2A2W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS01125 ^@ http://purl.uniprot.org/uniprot/B2A4E5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/457570:NTHER_RS10295 ^@ http://purl.uniprot.org/uniprot/B2A6Z9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/457570:NTHER_RS01700 ^@ http://purl.uniprot.org/uniprot/B2A573 ^@ Function|||Similarity ^@ Belongs to the PemK/MazF family.|||Toxic component of a type II toxin-antitoxin (TA) system. http://togogenome.org/gene/457570:NTHER_RS08225 ^@ http://purl.uniprot.org/uniprot/B2A4M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS05825 ^@ http://purl.uniprot.org/uniprot/B2A1J3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.|||Catalyzes the interconversion of ornithine to glutamate semialdehyde.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS06820 ^@ http://purl.uniprot.org/uniprot/B2A2L5 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/457570:NTHER_RS10365 ^@ http://purl.uniprot.org/uniprot/B2A713 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/457570:NTHER_RS05185 ^@ http://purl.uniprot.org/uniprot/B2A0X6 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/457570:NTHER_RS01830 ^@ http://purl.uniprot.org/uniprot/B2A598 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS02255 ^@ http://purl.uniprot.org/uniprot/B2A5S6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS14575 ^@ http://purl.uniprot.org/uniprot/B2A3K7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS14385 ^@ http://purl.uniprot.org/uniprot/B2A3H0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS00085 ^@ http://purl.uniprot.org/uniprot/B2A2Z7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/457570:NTHER_RS06625 ^@ http://purl.uniprot.org/uniprot/B2A2H6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/457570:NTHER_RS05715 ^@ http://purl.uniprot.org/uniprot/B2A1H0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ALAD family.|||Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.|||Homooctamer. http://togogenome.org/gene/457570:NTHER_RS08595 ^@ http://purl.uniprot.org/uniprot/B2A534 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/457570:NTHER_RS13845 ^@ http://purl.uniprot.org/uniprot/B2A2S5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/457570:NTHER_RS05590 ^@ http://purl.uniprot.org/uniprot/B2A159 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/457570:NTHER_RS14155 ^@ http://purl.uniprot.org/uniprot/B2A2Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS09980 ^@ http://purl.uniprot.org/uniprot/B2A6J9 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/457570:NTHER_RS02750 ^@ http://purl.uniprot.org/uniprot/B2A6A6 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/457570:NTHER_RS12100 ^@ http://purl.uniprot.org/uniprot/B2A0S0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS01595 ^@ http://purl.uniprot.org/uniprot/B2A4W8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS09820 ^@ http://purl.uniprot.org/uniprot/B2A6H6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/457570:NTHER_RS02490 ^@ http://purl.uniprot.org/uniprot/B2A5X3 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS10195 ^@ http://purl.uniprot.org/uniprot/B2A6Y0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/457570:NTHER_RS05760 ^@ http://purl.uniprot.org/uniprot/B2A1I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS14165 ^@ http://purl.uniprot.org/uniprot/B2A3C5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS03275 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS05240 ^@ http://purl.uniprot.org/uniprot/B2A0Y7 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/457570:NTHER_RS08575 ^@ http://purl.uniprot.org/uniprot/B2A530 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/457570:NTHER_RS11295 ^@ http://purl.uniprot.org/uniprot/B2A817 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/457570:NTHER_RS04590 ^@ http://purl.uniprot.org/uniprot/B2A8B4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/457570:NTHER_RS05500 ^@ http://purl.uniprot.org/uniprot/B2A145 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS00895 ^@ http://purl.uniprot.org/uniprot/B2A4A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS01250 ^@ http://purl.uniprot.org/uniprot/B2A4Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS08895 ^@ http://purl.uniprot.org/uniprot/B2A5H8 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/457570:NTHER_RS07460 ^@ http://purl.uniprot.org/uniprot/B2A3V5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/457570:NTHER_RS13910 ^@ http://purl.uniprot.org/uniprot/B2A2T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS06605 ^@ http://purl.uniprot.org/uniprot/B2A2H2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). http://togogenome.org/gene/457570:NTHER_RS01665 ^@ http://purl.uniprot.org/uniprot/B2A4X8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/457570:NTHER_RS06745 ^@ http://purl.uniprot.org/uniprot/B2A2K0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/457570:NTHER_RS07030 ^@ http://purl.uniprot.org/uniprot/B2A340 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/457570:NTHER_RS02695 ^@ http://purl.uniprot.org/uniprot/B2A695 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ApbE family.|||Cell inner membrane|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/457570:NTHER_RS01835 ^@ http://purl.uniprot.org/uniprot/B2A599 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS04470 ^@ http://purl.uniprot.org/uniprot/B2A889 ^@ Similarity ^@ Belongs to the AAE transporter (TC 2.A.81) family. http://togogenome.org/gene/457570:NTHER_RS07515 ^@ http://purl.uniprot.org/uniprot/B2A3W6 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/457570:NTHER_RS03165 ^@ http://purl.uniprot.org/uniprot/B2A6R5 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/457570:NTHER_RS00575 ^@ http://purl.uniprot.org/uniprot/B2A3S6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS03690 ^@ http://purl.uniprot.org/uniprot/B2A7A9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS01885 ^@ http://purl.uniprot.org/uniprot/B2A5A9 ^@ Similarity ^@ Belongs to the UPF0751 family. http://togogenome.org/gene/457570:NTHER_RS02955 ^@ http://purl.uniprot.org/uniprot/B2A6E9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/457570:NTHER_RS12195 ^@ http://purl.uniprot.org/uniprot/B2A0T9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS00040 ^@ http://purl.uniprot.org/uniprot/B2A2Z3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/457570:NTHER_RS10925 ^@ http://purl.uniprot.org/uniprot/B2A7K6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS08410 ^@ http://purl.uniprot.org/uniprot/B2A4Z7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS10275 ^@ http://purl.uniprot.org/uniprot/B2A6Z5 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/457570:NTHER_RS00255 ^@ http://purl.uniprot.org/uniprot/B2A328 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS13635 ^@ http://purl.uniprot.org/uniprot/B2A2E9 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/457570:NTHER_RS13955 ^@ http://purl.uniprot.org/uniprot/B2A2U7 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/457570:NTHER_RS02665 ^@ http://purl.uniprot.org/uniprot/B2A688 ^@ Similarity ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family. http://togogenome.org/gene/457570:NTHER_RS02655 ^@ http://purl.uniprot.org/uniprot/B2A686 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS05815 ^@ http://purl.uniprot.org/uniprot/B2A1J1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS09275 ^@ http://purl.uniprot.org/uniprot/B2A5Z0 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/457570:NTHER_RS07010 ^@ http://purl.uniprot.org/uniprot/B2A337 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS14775 ^@ http://purl.uniprot.org/uniprot/B2A465 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/457570:NTHER_RS14645 ^@ http://purl.uniprot.org/uniprot/B2A444 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS05515 ^@ http://purl.uniprot.org/uniprot/B2A149 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/457570:NTHER_RS04670 ^@ http://purl.uniprot.org/uniprot/B2A8D0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily.|||Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS02195 ^@ http://purl.uniprot.org/uniprot/B2A5Q8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS00795 ^@ http://purl.uniprot.org/uniprot/B2A486 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS09260 ^@ http://purl.uniprot.org/uniprot/B2A5Y7 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/457570:NTHER_RS03605 ^@ http://purl.uniprot.org/uniprot/B2A791 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/457570:NTHER_RS00330 ^@ http://purl.uniprot.org/uniprot/B2A3M9 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/457570:NTHER_RS11925 ^@ http://purl.uniprot.org/uniprot/B2A8N2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/457570:NTHER_RS03550 ^@ http://purl.uniprot.org/uniprot/B2A780 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/457570:NTHER_RS14600 ^@ http://purl.uniprot.org/uniprot/B2A3L2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/457570:NTHER_RS10465 ^@ http://purl.uniprot.org/uniprot/B2A731 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/457570:NTHER_RS01165 ^@ http://purl.uniprot.org/uniprot/B2A4F3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/457570:NTHER_RS05155 ^@ http://purl.uniprot.org/uniprot/B2A0N5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS02950 ^@ http://purl.uniprot.org/uniprot/B2A6E5 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/457570:NTHER_RS01720 ^@ http://purl.uniprot.org/uniprot/B2A577 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/457570:NTHER_RS02650 ^@ http://purl.uniprot.org/uniprot/B2A685 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/457570:NTHER_RS01060 ^@ http://purl.uniprot.org/uniprot/B2A4D2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/457570:NTHER_RS04395 ^@ http://purl.uniprot.org/uniprot/B2A874 ^@ Similarity ^@ Belongs to the ThrE exporter (TC 2.A.79) family. http://togogenome.org/gene/457570:NTHER_RS02640 ^@ http://purl.uniprot.org/uniprot/B2A683 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS06575 ^@ http://purl.uniprot.org/uniprot/B2A2G6 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/457570:NTHER_RS14565 ^@ http://purl.uniprot.org/uniprot/B2A3K5 ^@ Activity Regulation|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer. http://togogenome.org/gene/457570:NTHER_RS14945 ^@ http://purl.uniprot.org/uniprot/B2A8Q5 ^@ Similarity ^@ Belongs to the PemK/MazF family. http://togogenome.org/gene/457570:NTHER_RS03575 ^@ http://purl.uniprot.org/uniprot/B2A785 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS12245 ^@ http://purl.uniprot.org/uniprot/B2A0U9 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily. http://togogenome.org/gene/457570:NTHER_RS10435 ^@ http://purl.uniprot.org/uniprot/B2A725 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS13260 ^@ http://purl.uniprot.org/uniprot/B2A273 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS09955 ^@ http://purl.uniprot.org/uniprot/B2A6J4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0756 family.|||Cell membrane http://togogenome.org/gene/457570:NTHER_RS05225 ^@ http://purl.uniprot.org/uniprot/B2A0Y4 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/457570:NTHER_RS08210 ^@ http://purl.uniprot.org/uniprot/B2A4M4 ^@ Function|||Subcellular Location Annotation ^@ ATPase. Has a role at an early stage in the morphogenesis of the spore coat.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS10425 ^@ http://purl.uniprot.org/uniprot/B2A723 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS10625 ^@ http://purl.uniprot.org/uniprot/B2A7E5 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/457570:NTHER_RS12175 ^@ http://purl.uniprot.org/uniprot/B2A0T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS15255 ^@ http://purl.uniprot.org/uniprot/B2A617 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/457570:NTHER_RS12580 ^@ http://purl.uniprot.org/uniprot/B2A1A9 ^@ Similarity ^@ Belongs to the ThiD family. http://togogenome.org/gene/457570:NTHER_RS06195 ^@ http://purl.uniprot.org/uniprot/B2A200 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/457570:NTHER_RS14695 ^@ http://purl.uniprot.org/uniprot/B2A449 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/457570:NTHER_RS10735 ^@ http://purl.uniprot.org/uniprot/B2A7G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS10355 ^@ http://purl.uniprot.org/uniprot/B2A711 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/457570:NTHER_RS06710 ^@ http://purl.uniprot.org/uniprot/B2A2J3 ^@ Function|||Similarity|||Subunit ^@ Associates with stalled 50S ribosomal subunits.|||Belongs to the NEMF family.|||Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. http://togogenome.org/gene/457570:NTHER_RS08685 ^@ http://purl.uniprot.org/uniprot/B2A551 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/457570:NTHER_RS12430 ^@ http://purl.uniprot.org/uniprot/B2A178 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS02645 ^@ http://purl.uniprot.org/uniprot/B2A684 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS09690 ^@ http://purl.uniprot.org/uniprot/B2A6F2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/457570:NTHER_RS03515 ^@ http://purl.uniprot.org/uniprot/B2A0V7 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/457570:NTHER_RS05530 ^@ http://purl.uniprot.org/uniprot/B2A152 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/457570:NTHER_RS11870 ^@ http://purl.uniprot.org/uniprot/B2A8M0 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/457570:NTHER_RS05880 ^@ http://purl.uniprot.org/uniprot/B2A1K5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS15330 ^@ http://purl.uniprot.org/uniprot/B2A7X6 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/457570:NTHER_RS16410 ^@ http://purl.uniprot.org/uniprot/B2A0Q5 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/457570:NTHER_RS04725 ^@ http://purl.uniprot.org/uniprot/B2A8E0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS13975 ^@ http://purl.uniprot.org/uniprot/B2A2V1 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/457570:NTHER_RS03915 ^@ http://purl.uniprot.org/uniprot/B2A7P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS02495 ^@ http://purl.uniprot.org/uniprot/B2A5X4 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/457570:NTHER_RS05105 ^@ http://purl.uniprot.org/uniprot/B2A0M4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS07255 ^@ http://purl.uniprot.org/uniprot/B2A386 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS02320 ^@ http://purl.uniprot.org/uniprot/B2A5T9 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/457570:NTHER_RS05725 ^@ http://purl.uniprot.org/uniprot/B2A1H2 ^@ Similarity ^@ Belongs to the Ahb/Nir family. http://togogenome.org/gene/457570:NTHER_RS13370 ^@ http://purl.uniprot.org/uniprot/B2A298 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS02360 ^@ http://purl.uniprot.org/uniprot/B2A5U7 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/457570:NTHER_RS14015 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS05930 ^@ http://purl.uniprot.org/uniprot/B2A1L5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/457570:NTHER_RS08545 ^@ http://purl.uniprot.org/uniprot/B2A524 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. http://togogenome.org/gene/457570:NTHER_RS06965 ^@ http://purl.uniprot.org/uniprot/B2A2P1 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/457570:NTHER_RS09375 ^@ http://purl.uniprot.org/uniprot/B2A610 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. AddA subfamily.|||Heterodimer of AddA and AddB/RexB.|||The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities. http://togogenome.org/gene/457570:NTHER_RS09710 ^@ http://purl.uniprot.org/uniprot/B2A6F6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/457570:NTHER_RS04255 ^@ http://purl.uniprot.org/uniprot/B2A7W4 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/457570:NTHER_RS04730 ^@ http://purl.uniprot.org/uniprot/B2A8E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS05625 ^@ http://purl.uniprot.org/uniprot/B2A1F2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/457570:NTHER_RS05985 ^@ http://purl.uniprot.org/uniprot/B2A1M9 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/457570:NTHER_RS13680 ^@ http://purl.uniprot.org/uniprot/B2A2P6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS12285 ^@ http://purl.uniprot.org/uniprot/B2A0V7 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/457570:NTHER_RS07150 ^@ http://purl.uniprot.org/uniprot/B2A365 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/457570:NTHER_RS07230 ^@ http://purl.uniprot.org/uniprot/B2A381 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS13965 ^@ http://purl.uniprot.org/uniprot/B2A2U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS08275 ^@ http://purl.uniprot.org/uniprot/B2A4N7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/457570:NTHER_RS12065 ^@ http://purl.uniprot.org/uniprot/B2A0R3 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/457570:NTHER_RS02475 ^@ http://purl.uniprot.org/uniprot/B2A5X0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/457570:NTHER_RS11885 ^@ http://purl.uniprot.org/uniprot/B2A8M3 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/457570:NTHER_RS08970 ^@ http://purl.uniprot.org/uniprot/B2A5J3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/457570:NTHER_RS09475 ^@ http://purl.uniprot.org/uniprot/B2A627 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/457570:NTHER_RS05655 ^@ http://purl.uniprot.org/uniprot/B2A1F7 ^@ Function ^@ Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. http://togogenome.org/gene/457570:NTHER_RS10865 ^@ http://purl.uniprot.org/uniprot/B2A7J4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/457570:NTHER_RS01095 ^@ http://purl.uniprot.org/uniprot/B2A4D9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/457570:NTHER_RS01120 ^@ http://purl.uniprot.org/uniprot/B2A4E4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). http://togogenome.org/gene/457570:NTHER_RS06660 ^@ http://purl.uniprot.org/uniprot/B2A2I3 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/457570:NTHER_RS02290 ^@ http://purl.uniprot.org/uniprot/B2A5T3 ^@ Similarity ^@ Belongs to the diacylglycerol/lipid kinase family. http://togogenome.org/gene/457570:NTHER_RS02400 ^@ http://purl.uniprot.org/uniprot/B2A5V5 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS06730 ^@ http://purl.uniprot.org/uniprot/B2A2J7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/457570:NTHER_RS03685 ^@ http://purl.uniprot.org/uniprot/B2A7A8 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/457570:NTHER_RS01200 ^@ http://purl.uniprot.org/uniprot/B2A4G2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/457570:NTHER_RS02620 ^@ http://purl.uniprot.org/uniprot/B2A679 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS04480 ^@ http://purl.uniprot.org/uniprot/B2A891 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS03830 ^@ http://purl.uniprot.org/uniprot/B2A7D5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell membrane|||Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS01145 ^@ http://purl.uniprot.org/uniprot/B2A4E9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/457570:NTHER_RS11160 ^@ http://purl.uniprot.org/uniprot/B2A7Y9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. http://togogenome.org/gene/457570:NTHER_RS00125 ^@ http://purl.uniprot.org/uniprot/B2A300 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/457570:NTHER_RS09915 ^@ http://purl.uniprot.org/uniprot/B2A6I6 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/457570:NTHER_RS10845 ^@ http://purl.uniprot.org/uniprot/B2A7J0 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/457570:NTHER_RS01265 ^@ http://purl.uniprot.org/uniprot/B2A4Q5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS07115 ^@ http://purl.uniprot.org/uniprot/B2A358 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS12530 ^@ http://purl.uniprot.org/uniprot/B2A199 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS02895 ^@ http://purl.uniprot.org/uniprot/B2A6D4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-C family. DnaE subfamily.|||Cytoplasm|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase. http://togogenome.org/gene/457570:NTHER_RS10245 ^@ http://purl.uniprot.org/uniprot/B2A6Y9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Requires K(+) for maximal activity.|||Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. http://togogenome.org/gene/457570:NTHER_RS12650 ^@ http://purl.uniprot.org/uniprot/B2A1C4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS09990 ^@ http://purl.uniprot.org/uniprot/B2A6K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CotF family.|||Spore coat http://togogenome.org/gene/457570:NTHER_RS01505 ^@ http://purl.uniprot.org/uniprot/B2A4V0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS03305 ^@ http://purl.uniprot.org/uniprot/B2A6U4 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/457570:NTHER_RS02425 ^@ http://purl.uniprot.org/uniprot/B2A5W0 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS09160 ^@ http://purl.uniprot.org/uniprot/B2A5N1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS07325 ^@ http://purl.uniprot.org/uniprot/B2A3A0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/457570:NTHER_RS14525 ^@ http://purl.uniprot.org/uniprot/B2A3J7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS00035 ^@ http://purl.uniprot.org/uniprot/B2A2Z2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/457570:NTHER_RS10155 ^@ http://purl.uniprot.org/uniprot/B2A6W9 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/457570:NTHER_RS01075 ^@ http://purl.uniprot.org/uniprot/B2A4D5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/457570:NTHER_RS06665 ^@ http://purl.uniprot.org/uniprot/B2A2I4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/457570:NTHER_RS00770 ^@ http://purl.uniprot.org/uniprot/B2A481 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/457570:NTHER_RS00320 ^@ http://purl.uniprot.org/uniprot/B2A3M7 ^@ Function|||Similarity ^@ Belongs to the peptidase S51 family.|||Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides. http://togogenome.org/gene/457570:NTHER_RS11415 ^@ http://purl.uniprot.org/uniprot/B2A845 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/457570:NTHER_RS00010 ^@ http://purl.uniprot.org/uniprot/B2A2Y7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/457570:NTHER_RS14215 ^@ http://purl.uniprot.org/uniprot/B2A3D6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS00950 ^@ http://purl.uniprot.org/uniprot/B2A4B5 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/457570:NTHER_RS01030 ^@ http://purl.uniprot.org/uniprot/B2A4C6 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/457570:NTHER_RS11855 ^@ http://purl.uniprot.org/uniprot/B2A8L8 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/457570:NTHER_RS01240 ^@ http://purl.uniprot.org/uniprot/B2A4Q0 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/457570:NTHER_RS06115 ^@ http://purl.uniprot.org/uniprot/B2A1Y8 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/457570:NTHER_RS06410 ^@ http://purl.uniprot.org/uniprot/B2A242 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/457570:NTHER_RS14440 ^@ http://purl.uniprot.org/uniprot/B2A3I0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/457570:NTHER_RS12520 ^@ http://purl.uniprot.org/uniprot/B2A197 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane|||Part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/457570:NTHER_RS06565 ^@ http://purl.uniprot.org/uniprot/B2A2G4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/457570:NTHER_RS05975 ^@ http://purl.uniprot.org/uniprot/B2A1M7 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/457570:NTHER_RS13375 ^@ http://purl.uniprot.org/uniprot/B2A299 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/457570:NTHER_RS05990 ^@ http://purl.uniprot.org/uniprot/B2A1N0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/457570:NTHER_RS06620 ^@ http://purl.uniprot.org/uniprot/B2A2H5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/457570:NTHER_RS14490 ^@ http://purl.uniprot.org/uniprot/B2A3J0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/457570:NTHER_RS13310 ^@ http://purl.uniprot.org/uniprot/B2A283 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS00215 ^@ http://purl.uniprot.org/uniprot/B2A320 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/457570:NTHER_RS11410 ^@ http://purl.uniprot.org/uniprot/B2A844 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS07140 ^@ http://purl.uniprot.org/uniprot/B2A363 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/457570:NTHER_RS02680 ^@ http://purl.uniprot.org/uniprot/B2A692 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS00590 ^@ http://purl.uniprot.org/uniprot/B2A3S9 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/457570:NTHER_RS01310 ^@ http://purl.uniprot.org/uniprot/B2A4R3 ^@ Cofactor|||Similarity ^@ Belongs to the arginase family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/457570:NTHER_RS00535 ^@ http://purl.uniprot.org/uniprot/B2A3R9 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/457570:NTHER_RS01325 ^@ http://purl.uniprot.org/uniprot/B2A4R6 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/457570:NTHER_RS12590 ^@ http://purl.uniprot.org/uniprot/B2A1B1 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/457570:NTHER_RS14795 ^@ http://purl.uniprot.org/uniprot/B2A469 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/457570:NTHER_RS12815 ^@ http://purl.uniprot.org/uniprot/B2A1P7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/457570:NTHER_RS04645 ^@ http://purl.uniprot.org/uniprot/B2A8C5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/457570:NTHER_RS12260 ^@ http://purl.uniprot.org/uniprot/B2A0V2 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/457570:NTHER_RS14175 ^@ http://purl.uniprot.org/uniprot/B2A3C7 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/457570:NTHER_RS09665 ^@ http://purl.uniprot.org/uniprot/B2A667 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/457570:NTHER_RS15250 ^@ http://purl.uniprot.org/uniprot/B2A5Z3 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/457570:NTHER_RS05870 ^@ http://purl.uniprot.org/uniprot/B2A1K3 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/457570:NTHER_RS05065 ^@ http://purl.uniprot.org/uniprot/B2A0L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS03405 ^@ http://purl.uniprot.org/uniprot/B2A6W4 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/457570:NTHER_RS01345 ^@ http://purl.uniprot.org/uniprot/B2A0U4 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/457570:NTHER_RS07080 ^@ http://purl.uniprot.org/uniprot/B2A350 ^@ Similarity ^@ Belongs to the FlgD family. http://togogenome.org/gene/457570:NTHER_RS06750 ^@ http://purl.uniprot.org/uniprot/B2A2K1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/457570:NTHER_RS07445 ^@ http://purl.uniprot.org/uniprot/B2A3C4 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/457570:NTHER_RS03815 ^@ http://purl.uniprot.org/uniprot/B2A7D2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS06830 ^@ http://purl.uniprot.org/uniprot/B2A2L7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/457570:NTHER_RS04985 ^@ http://purl.uniprot.org/uniprot/B2A0J7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/457570:NTHER_RS14820 ^@ http://purl.uniprot.org/uniprot/B2A475 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/457570:NTHER_RS12805 ^@ http://purl.uniprot.org/uniprot/B2A1P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS00645 ^@ http://purl.uniprot.org/uniprot/B2A3U0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/457570:NTHER_RS14120 ^@ http://purl.uniprot.org/uniprot/B2A2X7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS06205 ^@ http://purl.uniprot.org/uniprot/B2A202 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/457570:NTHER_RS06430 ^@ http://purl.uniprot.org/uniprot/B2A246 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/457570:NTHER_RS07840 ^@ http://purl.uniprot.org/uniprot/B2A427 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS16080 ^@ http://purl.uniprot.org/uniprot/B2A3L8 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/457570:NTHER_RS11535 ^@ http://purl.uniprot.org/uniprot/B2A8F2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/457570:NTHER_RS14290 ^@ http://purl.uniprot.org/uniprot/B2A3F1 ^@ Similarity|||Subunit ^@ Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/457570:NTHER_RS03075 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS12495 ^@ http://purl.uniprot.org/uniprot/B2A194 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS01135 ^@ http://purl.uniprot.org/uniprot/B2A4E7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/457570:NTHER_RS01255 ^@ http://purl.uniprot.org/uniprot/B2A4Q3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.|||Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).|||Membrane http://togogenome.org/gene/457570:NTHER_RS11270 ^@ http://purl.uniprot.org/uniprot/B2A812 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/457570:NTHER_RS07680 ^@ http://purl.uniprot.org/uniprot/B2A3Z7 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/457570:NTHER_RS04880 ^@ http://purl.uniprot.org/uniprot/B2A0H5 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/457570:NTHER_RS14350 ^@ http://purl.uniprot.org/uniprot/B2A3G3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/457570:NTHER_RS05520 ^@ http://purl.uniprot.org/uniprot/B2A150 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS00200 ^@ http://purl.uniprot.org/uniprot/B2A317 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS14585 ^@ http://purl.uniprot.org/uniprot/B2A3K9 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/457570:NTHER_RS05555 ^@ http://purl.uniprot.org/uniprot/B2A160 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS06725 ^@ http://purl.uniprot.org/uniprot/B2A2J6 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/457570:NTHER_RS01010 ^@ http://purl.uniprot.org/uniprot/B2A4C2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/457570:NTHER_RS00840 ^@ http://purl.uniprot.org/uniprot/B2A494 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/457570:NTHER_RS06595 ^@ http://purl.uniprot.org/uniprot/B2A2H0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS07035 ^@ http://purl.uniprot.org/uniprot/B2A341 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/457570:NTHER_RS09180 ^@ http://purl.uniprot.org/uniprot/B2A5N5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/457570:NTHER_RS01105 ^@ http://purl.uniprot.org/uniprot/B2A4E1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/457570:NTHER_RS04755 ^@ http://purl.uniprot.org/uniprot/B2A0F1 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/457570:NTHER_RS14280 ^@ http://purl.uniprot.org/uniprot/B2A3E9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/457570:NTHER_RS13615 ^@ http://purl.uniprot.org/uniprot/B2A2E5 ^@ Function|||Subunit ^@ Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/457570:NTHER_RS09435 ^@ http://purl.uniprot.org/uniprot/B2A619 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/457570:NTHER_RS10605 ^@ http://purl.uniprot.org/uniprot/B2A6X4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/457570:NTHER_RS04785 ^@ http://purl.uniprot.org/uniprot/B2A0F7 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/457570:NTHER_RS09780 ^@ http://purl.uniprot.org/uniprot/B2A6G8 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/457570:NTHER_RS14300 ^@ http://purl.uniprot.org/uniprot/B2A3F3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS09745 ^@ http://purl.uniprot.org/uniprot/B2A6G2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS07950 ^@ http://purl.uniprot.org/uniprot/B2A4H2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS01650 ^@ http://purl.uniprot.org/uniprot/B2A4X5 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/457570:NTHER_RS00360 ^@ http://purl.uniprot.org/uniprot/B2A3N5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/457570:NTHER_RS09330 ^@ http://purl.uniprot.org/uniprot/B2A601 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/457570:NTHER_RS06775 ^@ http://purl.uniprot.org/uniprot/B2A2K6 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/457570:NTHER_RS06415 ^@ http://purl.uniprot.org/uniprot/B2A243 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/457570:NTHER_RS11150 ^@ http://purl.uniprot.org/uniprot/B2A7Y7 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/457570:NTHER_RS00760 ^@ http://purl.uniprot.org/uniprot/B2A479 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/457570:NTHER_RS10995 ^@ http://purl.uniprot.org/uniprot/B2A7M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS13525 ^@ http://purl.uniprot.org/uniprot/B2A2C8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS02740 ^@ http://purl.uniprot.org/uniprot/B2A6A4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/457570:NTHER_RS11740 ^@ http://purl.uniprot.org/uniprot/B2A8J6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS13775 ^@ http://purl.uniprot.org/uniprot/B2A2R3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS05685 ^@ http://purl.uniprot.org/uniprot/B2A1G4 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/457570:NTHER_RS07050 ^@ http://purl.uniprot.org/uniprot/B2A344 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS02825 ^@ http://purl.uniprot.org/uniprot/B2A6C1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/457570:NTHER_RS03535 ^@ http://purl.uniprot.org/uniprot/B2A777 ^@ Similarity ^@ Belongs to the DCK/DGK family. http://togogenome.org/gene/457570:NTHER_RS06225 ^@ http://purl.uniprot.org/uniprot/B2A205 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/457570:NTHER_RS07155 ^@ http://purl.uniprot.org/uniprot/B2A366 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/457570:NTHER_RS05435 ^@ http://purl.uniprot.org/uniprot/B2A133 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. http://togogenome.org/gene/457570:NTHER_RS01385 ^@ http://purl.uniprot.org/uniprot/B2A4S8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS14800 ^@ http://purl.uniprot.org/uniprot/B2A470 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits. http://togogenome.org/gene/457570:NTHER_RS02385 ^@ http://purl.uniprot.org/uniprot/B2A5V2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/457570:NTHER_RS09565 ^@ http://purl.uniprot.org/uniprot/B2A643 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS08115 ^@ http://purl.uniprot.org/uniprot/B2A4K4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/457570:NTHER_RS01130 ^@ http://purl.uniprot.org/uniprot/B2A4E6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/457570:NTHER_RS05485 ^@ http://purl.uniprot.org/uniprot/B2A142 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS02405 ^@ http://purl.uniprot.org/uniprot/B2A5V6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS08485 ^@ http://purl.uniprot.org/uniprot/B2A512 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS10960 ^@ http://purl.uniprot.org/uniprot/B2A7L3 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/457570:NTHER_RS04450 ^@ http://purl.uniprot.org/uniprot/B2A885 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS05630 ^@ http://purl.uniprot.org/uniprot/B2A1F3 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/457570:NTHER_RS13720 ^@ http://purl.uniprot.org/uniprot/B2A2Q3 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/457570:NTHER_RS07285 ^@ http://purl.uniprot.org/uniprot/B2A392 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. PolC subfamily.|||Cytoplasm|||Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/457570:NTHER_RS09430 ^@ http://purl.uniprot.org/uniprot/B2A618 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/457570:NTHER_RS06860 ^@ http://purl.uniprot.org/uniprot/B2A2M3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/457570:NTHER_RS06650 ^@ http://purl.uniprot.org/uniprot/B2A2I1 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/457570:NTHER_RS05235 ^@ http://purl.uniprot.org/uniprot/B2A0Y6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/457570:NTHER_RS12425 ^@ http://purl.uniprot.org/uniprot/B2A177 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS06170 ^@ http://purl.uniprot.org/uniprot/B2A1Z5 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/457570:NTHER_RS04110 ^@ http://purl.uniprot.org/uniprot/B2A7T2 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/457570:NTHER_RS11600 ^@ http://purl.uniprot.org/uniprot/B2A8G7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS06735 ^@ http://purl.uniprot.org/uniprot/B2A2J8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/457570:NTHER_RS13870 ^@ http://purl.uniprot.org/uniprot/B2A2T0 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/457570:NTHER_RS06995 ^@ http://purl.uniprot.org/uniprot/B2A334 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS06910 ^@ http://purl.uniprot.org/uniprot/B2A2N3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/457570:NTHER_RS08010 ^@ http://purl.uniprot.org/uniprot/B2A4I5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/457570:NTHER_RS03495 ^@ http://purl.uniprot.org/uniprot/B2A769 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS11345 ^@ http://purl.uniprot.org/uniprot/B2A827 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/457570:NTHER_RS01020 ^@ http://purl.uniprot.org/uniprot/B2A4C4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/457570:NTHER_RS04700 ^@ http://purl.uniprot.org/uniprot/B2A8D5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS06970 ^@ http://purl.uniprot.org/uniprot/B2A329 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/457570:NTHER_RS11335 ^@ http://purl.uniprot.org/uniprot/B2A825 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/457570:NTHER_RS00075 ^@ http://purl.uniprot.org/uniprot/B2A2Z5 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/457570:NTHER_RS11820 ^@ http://purl.uniprot.org/uniprot/B2A8L1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/457570:NTHER_RS02810 ^@ http://purl.uniprot.org/uniprot/B2A6B8 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/457570:NTHER_RS01760 ^@ http://purl.uniprot.org/uniprot/B2A584 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS07455 ^@ http://purl.uniprot.org/uniprot/B2A3V4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS14395 ^@ http://purl.uniprot.org/uniprot/B2A3H1 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/457570:NTHER_RS08340 ^@ http://purl.uniprot.org/uniprot/B2A4Y3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpB family.|||Cytoplasm|||Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/457570:NTHER_RS03330 ^@ http://purl.uniprot.org/uniprot/B2A6U9 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/457570:NTHER_RS04655 ^@ http://purl.uniprot.org/uniprot/B2A8C7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0182 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS00460 ^@ http://purl.uniprot.org/uniprot/B2A3Q4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/457570:NTHER_RS09345 ^@ http://purl.uniprot.org/uniprot/B2A604 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/457570:NTHER_RS01110 ^@ http://purl.uniprot.org/uniprot/B2A4E2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/457570:NTHER_RS00480 ^@ http://purl.uniprot.org/uniprot/B2A3Q8 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/457570:NTHER_RS13090 ^@ http://purl.uniprot.org/uniprot/B2A1V1 ^@ Cofactor ^@ Binds 4 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/457570:NTHER_RS14805 ^@ http://purl.uniprot.org/uniprot/B2A471 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpB RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpA.|||Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H). http://togogenome.org/gene/457570:NTHER_RS05135 ^@ http://purl.uniprot.org/uniprot/B2A0N1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS08230 ^@ http://purl.uniprot.org/uniprot/B2A4M8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably interacts with PlsX. http://togogenome.org/gene/457570:NTHER_RS13875 ^@ http://purl.uniprot.org/uniprot/B2A2T1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. C-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/457570:NTHER_RS03160 ^@ http://purl.uniprot.org/uniprot/B2A6R4 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/457570:NTHER_RS13925 ^@ http://purl.uniprot.org/uniprot/B2A2U1 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/457570:NTHER_RS10505 ^@ http://purl.uniprot.org/uniprot/B2A739 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS01090 ^@ http://purl.uniprot.org/uniprot/B2A4D8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/457570:NTHER_RS15105 ^@ http://purl.uniprot.org/uniprot/B2A881 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS14725 ^@ http://purl.uniprot.org/uniprot/B2A455 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS06940 ^@ http://purl.uniprot.org/uniprot/B2A2N9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/457570:NTHER_RS08690 ^@ http://purl.uniprot.org/uniprot/B2A552 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/457570:NTHER_RS04400 ^@ http://purl.uniprot.org/uniprot/B2A875 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/457570:NTHER_RS05110 ^@ http://purl.uniprot.org/uniprot/B2A0M5 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/457570:NTHER_RS00565 ^@ http://purl.uniprot.org/uniprot/B2A3S4 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/457570:NTHER_RS09920 ^@ http://purl.uniprot.org/uniprot/B2A6I7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/457570:NTHER_RS10890 ^@ http://purl.uniprot.org/uniprot/B2A7J9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS06790 ^@ http://purl.uniprot.org/uniprot/B2A2K9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/457570:NTHER_RS11420 ^@ http://purl.uniprot.org/uniprot/B2A846 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/457570:NTHER_RS13530 ^@ http://purl.uniprot.org/uniprot/B2A2C9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS08400 ^@ http://purl.uniprot.org/uniprot/B2A4Z5 ^@ Function|||Similarity ^@ Belongs to the anti-sigma-factor antagonist family.|||In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition. http://togogenome.org/gene/457570:NTHER_RS02465 ^@ http://purl.uniprot.org/uniprot/B2A5W8 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/457570:NTHER_RS06700 ^@ http://purl.uniprot.org/uniprot/B2A2J1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/457570:NTHER_RS08925 ^@ http://purl.uniprot.org/uniprot/B2A5I4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS00700 ^@ http://purl.uniprot.org/uniprot/B2A3U5 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/457570:NTHER_RS08325 ^@ http://purl.uniprot.org/uniprot/B2A4K0 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/457570:NTHER_RS12975 ^@ http://purl.uniprot.org/uniprot/B2A1S9 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/457570:NTHER_RS08490 ^@ http://purl.uniprot.org/uniprot/B2A513 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/457570:NTHER_RS01280 ^@ http://purl.uniprot.org/uniprot/B2A4Q8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/457570:NTHER_RS09350 ^@ http://purl.uniprot.org/uniprot/B2A605 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/457570:NTHER_RS06915 ^@ http://purl.uniprot.org/uniprot/B2A2N4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/457570:NTHER_RS16310 ^@ http://purl.uniprot.org/uniprot/B2A3G8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/457570:NTHER_RS08395 ^@ http://purl.uniprot.org/uniprot/B2A4Z4 ^@ Function|||Similarity ^@ Belongs to the anti-sigma-factor family.|||Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. http://togogenome.org/gene/457570:NTHER_RS06360 ^@ http://purl.uniprot.org/uniprot/B2A232 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/457570:NTHER_RS11825 ^@ http://purl.uniprot.org/uniprot/B2A8L2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/457570:NTHER_RS06890 ^@ http://purl.uniprot.org/uniprot/B2A2M9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/457570:NTHER_RS05000 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS06805 ^@ http://purl.uniprot.org/uniprot/B2A2L2 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/457570:NTHER_RS01225 ^@ http://purl.uniprot.org/uniprot/B2A4P7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/457570:NTHER_RS13125 ^@ http://purl.uniprot.org/uniprot/B2A1V8 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase family. http://togogenome.org/gene/457570:NTHER_RS04495 ^@ http://purl.uniprot.org/uniprot/B2A895 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/457570:NTHER_RS09280 ^@ http://purl.uniprot.org/uniprot/B2A5Z1 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/457570:NTHER_RS07015 ^@ http://purl.uniprot.org/uniprot/B2A338 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CodY family.|||Cytoplasm|||DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion. http://togogenome.org/gene/457570:NTHER_RS13930 ^@ http://purl.uniprot.org/uniprot/B2A2U2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS12330 ^@ http://purl.uniprot.org/uniprot/B2A0W5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/457570:NTHER_RS04945 ^@ http://purl.uniprot.org/uniprot/B2A0I9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS03800 ^@ http://purl.uniprot.org/uniprot/B2A7C9 ^@ Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family. http://togogenome.org/gene/457570:NTHER_RS13780 ^@ http://purl.uniprot.org/uniprot/B2A2R4 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/457570:NTHER_RS05290 ^@ http://purl.uniprot.org/uniprot/B2A0Z8 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/457570:NTHER_RS00385 ^@ http://purl.uniprot.org/uniprot/B2A3P0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/457570:NTHER_RS00325 ^@ http://purl.uniprot.org/uniprot/B2A3M8 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).|||Homodimer.|||In the C-terminal section; belongs to the MurCDEF family. http://togogenome.org/gene/457570:NTHER_RS01895 ^@ http://purl.uniprot.org/uniprot/B2A5B1 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/457570:NTHER_RS08005 ^@ http://purl.uniprot.org/uniprot/B2A4I3 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/457570:NTHER_RS05160 ^@ http://purl.uniprot.org/uniprot/B2A0N6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/457570:NTHER_RS11260 ^@ http://purl.uniprot.org/uniprot/B2A809 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS06800 ^@ http://purl.uniprot.org/uniprot/B2A2L1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/457570:NTHER_RS06215 ^@ http://purl.uniprot.org/uniprot/B2A204 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/457570:NTHER_RS07005 ^@ http://purl.uniprot.org/uniprot/B2A336 ^@ Similarity ^@ Belongs to the peptidase T1B family. HslV subfamily. http://togogenome.org/gene/457570:NTHER_RS12995 ^@ http://purl.uniprot.org/uniprot/B2A1T3 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/457570:NTHER_RS04825 ^@ http://purl.uniprot.org/uniprot/B2A0G5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/457570:NTHER_RS05740 ^@ http://purl.uniprot.org/uniprot/B2A1H5 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/457570:NTHER_RS00400 ^@ http://purl.uniprot.org/uniprot/B2A3P3 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/457570:NTHER_RS05460 ^@ http://purl.uniprot.org/uniprot/B2A137 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell membrane|||Component of the transport system for branched-chain amino acids.|||Membrane http://togogenome.org/gene/457570:NTHER_RS06935 ^@ http://purl.uniprot.org/uniprot/B2A2N8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/457570:NTHER_RS14815 ^@ http://purl.uniprot.org/uniprot/B2A474 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/457570:NTHER_RS10525 ^@ http://purl.uniprot.org/uniprot/B2A0J9 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/457570:NTHER_RS02445 ^@ http://purl.uniprot.org/uniprot/B2A5W4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/457570:NTHER_RS09045 ^@ http://purl.uniprot.org/uniprot/B2A5L1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/457570:NTHER_RS00720 ^@ http://purl.uniprot.org/uniprot/B2A3U9 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/457570:NTHER_RS07390 ^@ http://purl.uniprot.org/uniprot/B2A3B3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/457570:NTHER_RS10895 ^@ http://purl.uniprot.org/uniprot/B2A7K0 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/457570:NTHER_RS02670 ^@ http://purl.uniprot.org/uniprot/B2A689 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/457570:NTHER_RS11070 ^@ http://purl.uniprot.org/uniprot/B2A0U4 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/457570:NTHER_RS15150 ^@ http://purl.uniprot.org/uniprot/B2A0J0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0182 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/457570:NTHER_RS13095 ^@ http://purl.uniprot.org/uniprot/B2A1V2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/457570:NTHER_RS13660 ^@ http://purl.uniprot.org/uniprot/B2A2F4 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/457570:NTHER_RS03870 ^@ http://purl.uniprot.org/uniprot/B2A7N5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/457570:NTHER_RS14465 ^@ http://purl.uniprot.org/uniprot/B2A3I5 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/457570:NTHER_RS07275 ^@ http://purl.uniprot.org/uniprot/B2A390 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.