http://togogenome.org/gene/470934:EGO56_RS15250 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5C1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/470934:EGO56_RS18895 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q373 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/470934:EGO56_RS13525 ^@ http://purl.uniprot.org/uniprot/A0A7U4TAU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/470934:EGO56_RS05750 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbE subfamily.|||Cell inner membrane http://togogenome.org/gene/470934:EGO56_RS02320 ^@ http://purl.uniprot.org/uniprot/A0A1W9EMQ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/470934:EGO56_RS17300 ^@ http://purl.uniprot.org/uniprot/A0A120LNU8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/470934:EGO56_RS07130 ^@ http://purl.uniprot.org/uniprot/A0A7U4TC90 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS10715 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3R4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/470934:EGO56_RS06570 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y292 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS17160 ^@ http://purl.uniprot.org/uniprot/A0A109YAA6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/470934:EGO56_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2I1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/470934:EGO56_RS07585 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2C6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/470934:EGO56_RS15825 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q5V6 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/470934:EGO56_RS18510 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3Z0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. WecA subfamily.|||Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS04450 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1B0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/470934:EGO56_RS17260 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q5H0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RapZ-like family. RapZ subfamily.|||Homotrimer.|||Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS. http://togogenome.org/gene/470934:EGO56_RS01500 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AYD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS12880 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q6R0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/470934:EGO56_RS15985 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y598 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/470934:EGO56_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1B4 ^@ Function|||Similarity ^@ Belongs to the arginase family. Agmatinase subfamily.|||Catalyzes the formation of putrescine from agmatine. http://togogenome.org/gene/470934:EGO56_RS15790 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0U1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.|||Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS00310 ^@ http://purl.uniprot.org/uniprot/A0A7U4T9X8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS10150 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y396 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS06255 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y288 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/470934:EGO56_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q4K5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS08910 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B259 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS01595 ^@ http://purl.uniprot.org/uniprot/A0A7U4QAV0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/470934:EGO56_RS17295 ^@ http://purl.uniprot.org/uniprot/A0A2R4J497 ^@ Similarity ^@ Belongs to the GST superfamily. HSP26 family. http://togogenome.org/gene/470934:EGO56_RS10565 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4E7 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/470934:EGO56_RS06590 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q8Y0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BexD/CtrA/VexA family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS04105 ^@ http://purl.uniprot.org/uniprot/A0A501SAU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS18675 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS21310 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B210 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/470934:EGO56_RS02235 ^@ http://purl.uniprot.org/uniprot/A0A7U4TC51 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/470934:EGO56_RS10265 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3C7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.|||Cell inner membrane|||Membrane|||Proton-dependent permease that transports di- and tripeptides. http://togogenome.org/gene/470934:EGO56_RS05550 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1L1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NRAMP family.|||Cell membrane|||H(+)-stimulated, divalent metal cation uptake system. http://togogenome.org/gene/470934:EGO56_RS11720 ^@ http://purl.uniprot.org/uniprot/A0A120LP58 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS13645 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q6P8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/470934:EGO56_RS18305 ^@ http://purl.uniprot.org/uniprot/A0A7U4TAH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LysR transcriptional regulatory family.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS14365 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4U0 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively. http://togogenome.org/gene/470934:EGO56_RS04235 ^@ http://purl.uniprot.org/uniprot/A0A2R4JB98 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1K1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/470934:EGO56_RS18865 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS03040 ^@ http://purl.uniprot.org/uniprot/A0A7U4QAA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS03610 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0Z7 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/470934:EGO56_RS13535 ^@ http://purl.uniprot.org/uniprot/A0A7U5Z4Q8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.|||Belongs to the AcrZ family.|||Cell membrane|||Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB. http://togogenome.org/gene/470934:EGO56_RS07885 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6E0 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/470934:EGO56_RS05730 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1P2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/470934:EGO56_RS15895 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5A4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/470934:EGO56_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2Q7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmD/CycX/HelD family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/470934:EGO56_RS00710 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y063 ^@ Similarity ^@ Belongs to the UPF0758 family. YicR subfamily. http://togogenome.org/gene/470934:EGO56_RS00695 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nucleoid occlusion factor SlmA family.|||Homodimer. Interacts with FtsZ.|||Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.|||nucleoid http://togogenome.org/gene/470934:EGO56_RS00565 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y014 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS15385 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2A4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/470934:EGO56_RS15910 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5N1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/470934:EGO56_RS14025 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS08165 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2W6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/470934:EGO56_RS08155 ^@ http://purl.uniprot.org/uniprot/A0A1W9EW16 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/470934:EGO56_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AYA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS01345 ^@ http://purl.uniprot.org/uniprot/A0A2R4J2U5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0114 family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS12815 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y467 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS13095 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q6Z9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS17920 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y698 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS16775 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2I5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/470934:EGO56_RS03135 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0Z1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/470934:EGO56_RS07460 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS03225 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B5C6 ^@ Function|||Similarity|||Subunit ^@ Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.|||Belongs to the Nudix hydrolase family. NudF subfamily.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS04500 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2B1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. http://togogenome.org/gene/470934:EGO56_RS13155 ^@ http://purl.uniprot.org/uniprot/A0A7U4TBG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS01685 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0B0 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/470934:EGO56_RS01620 ^@ http://purl.uniprot.org/uniprot/A0A5K5A8S4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS02770 ^@ http://purl.uniprot.org/uniprot/A0A7U4TC21 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PriB family.|||Binds single-stranded DNA at the primosome assembly site (PAS).|||Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome. http://togogenome.org/gene/470934:EGO56_RS01560 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2D1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sulfur carrier protein TusA family.|||Cytoplasm|||Interacts with IscS.|||Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. http://togogenome.org/gene/470934:EGO56_RS07900 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2M0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/470934:EGO56_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q3Q0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/470934:EGO56_RS06205 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q931 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/470934:EGO56_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A7U4TCC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS09310 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B285 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y207 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/470934:EGO56_RS08765 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q728 ^@ Similarity ^@ Belongs to the UPF0263 family. http://togogenome.org/gene/470934:EGO56_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6K9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the cytochrome b562 family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.|||Electron-transport protein of unknown function. http://togogenome.org/gene/470934:EGO56_RS14320 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4K4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS12970 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y492 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS14020 ^@ http://purl.uniprot.org/uniprot/A0A501SIE7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TatA/E family. TatE subfamily.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA. http://togogenome.org/gene/470934:EGO56_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q8F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS03325 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1E4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Cell membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/470934:EGO56_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A7U4TD66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/470934:EGO56_RS04470 ^@ http://purl.uniprot.org/uniprot/A0A109YBW0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/470934:EGO56_RS17345 ^@ http://purl.uniprot.org/uniprot/A0A1W9ER90 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/470934:EGO56_RS16055 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5F3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS07595 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q7K1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Flagellar protein that affects chemotactic events.|||Membrane http://togogenome.org/gene/470934:EGO56_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0P6 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase. http://togogenome.org/gene/470934:EGO56_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q487 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapB family.|||Cytoplasm|||Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.|||Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. http://togogenome.org/gene/470934:EGO56_RS02000 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0H0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/470934:EGO56_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0L4 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/470934:EGO56_RS16955 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5P4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase U32 family. UbiU subfamily.|||Forms an heterodimer with UbiV.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway. http://togogenome.org/gene/470934:EGO56_RS01095 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0U5 ^@ Similarity ^@ Belongs to the UPF0438 family. http://togogenome.org/gene/470934:EGO56_RS12985 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4E3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/470934:EGO56_RS15695 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3I1 ^@ Similarity ^@ Belongs to the UPF0231 family. http://togogenome.org/gene/470934:EGO56_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0Q2 ^@ Similarity ^@ Belongs to the UPF0307 family. http://togogenome.org/gene/470934:EGO56_RS04815 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q9L0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamE family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/470934:EGO56_RS12635 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1T7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapC family.|||Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.|||Cytoplasm|||Interacts directly with FtsZ. http://togogenome.org/gene/470934:EGO56_RS17340 ^@ http://purl.uniprot.org/uniprot/A0A109YCB3 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/470934:EGO56_RS02790 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0P5 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/470934:EGO56_RS15775 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the N-Me-Phe pilin family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS00825 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y086 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/470934:EGO56_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A7U4TCN4 ^@ Similarity ^@ Belongs to the UPF0125 (RnfH) family. http://togogenome.org/gene/470934:EGO56_RS21480 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7I2 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/470934:EGO56_RS12665 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y461 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the SsuD family.|||Catalyzes the desulfonation of aliphatic sulfonates.|||FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS16100 ^@ http://purl.uniprot.org/uniprot/A0A7U4TAN6 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/470934:EGO56_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0J5 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/470934:EGO56_RS01605 ^@ http://purl.uniprot.org/uniprot/A0A2R4J2Q0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/470934:EGO56_RS14720 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q698 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS05835 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1S3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/470934:EGO56_RS04100 ^@ http://purl.uniprot.org/uniprot/A0A1W9ERT9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS15395 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q621 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/470934:EGO56_RS15440 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4R7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/470934:EGO56_RS16990 ^@ http://purl.uniprot.org/uniprot/A0A5K4Z8C6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cell membrane|||Homodimer.|||May be involved in cell division. http://togogenome.org/gene/470934:EGO56_RS10075 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y475 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/470934:EGO56_RS17915 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5Z6 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS02945 ^@ http://purl.uniprot.org/uniprot/A0A2R4JC48 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SIS family. DiaA subfamily.|||Homotetramer; dimer of dimers.|||Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. http://togogenome.org/gene/470934:EGO56_RS06115 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZ52 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RcsD family.|||Cell inner membrane|||Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.|||Interacts with RcsC and RcsB.|||Phosphorylated by RcsC. http://togogenome.org/gene/470934:EGO56_RS01980 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9U3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/470934:EGO56_RS03200 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0U4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS05480 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0I8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS04425 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2A0 ^@ Similarity ^@ Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. http://togogenome.org/gene/470934:EGO56_RS00490 ^@ http://purl.uniprot.org/uniprot/A0A7Z1XZY1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/470934:EGO56_RS15805 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q5Y8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/470934:EGO56_RS03245 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B184 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/470934:EGO56_RS06100 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B352 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/470934:EGO56_RS03160 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2M7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.|||Homooctamer. http://togogenome.org/gene/470934:EGO56_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A2R4J987 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/470934:EGO56_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1H5 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/470934:EGO56_RS01140 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y088 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS17015 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3P9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/470934:EGO56_RS18115 ^@ http://purl.uniprot.org/uniprot/A0A7U4TA32 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NusG family.|||Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.|||Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination. http://togogenome.org/gene/470934:EGO56_RS15610 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3D2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS18290 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6E2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS05005 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q9N1 ^@ Cofactor|||Function ^@ Binds 1 [2Fe-2S] cluster.|||Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. http://togogenome.org/gene/470934:EGO56_RS01175 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0Z3 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/470934:EGO56_RS13595 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4M3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane|||Required for nicotinamide riboside transport across the inner membrane. http://togogenome.org/gene/470934:EGO56_RS11750 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4U7 ^@ Function|||Similarity ^@ Belongs to the DUF177 domain family.|||Plays a role in synthesis, processing and/or stability of 23S rRNA. http://togogenome.org/gene/470934:EGO56_RS05815 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2R2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS02735 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y135 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.|||Cytoplasm|||Homodimer.|||Specifically methylates the ribose of guanosine 2251 in 23S rRNA. http://togogenome.org/gene/470934:EGO56_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y194 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/470934:EGO56_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A7U4QAB4 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/470934:EGO56_RS15375 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3H1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS19865 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y700 ^@ Similarity ^@ Belongs to the HAM1 NTPase family. http://togogenome.org/gene/470934:EGO56_RS03665 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y111 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS20305 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B5S4 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/470934:EGO56_RS18890 ^@ http://purl.uniprot.org/uniprot/A0A1W9EQG4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/470934:EGO56_RS16010 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3F8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/470934:EGO56_RS17990 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y615 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. http://togogenome.org/gene/470934:EGO56_RS12390 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B085 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Cell inner membrane|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/470934:EGO56_RS01005 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y026 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS21955 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7Q3 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the SsuD family.|||Catalyzes the desulfonation of aliphatic sulfonates.|||FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS02155 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0P9 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/470934:EGO56_RS07550 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZE1 ^@ Function|||Similarity ^@ Belongs to the RcsA family.|||Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes. http://togogenome.org/gene/470934:EGO56_RS17880 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B166 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiC family.|||Cytoplasm|||Monomer.|||Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. http://togogenome.org/gene/470934:EGO56_RS06370 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2X9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm|||The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/470934:EGO56_RS18265 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y626 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC1 family. UbiB subfamily.|||Cell membrane|||Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS14570 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3C3 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/470934:EGO56_RS09420 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7G3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the rhamnose mutarotase family.|||Cytoplasm|||Homodimer.|||Involved in the anomeric conversion of L-rhamnose. http://togogenome.org/gene/470934:EGO56_RS18240 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q542 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RfaH family.|||Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.|||Interacts with both the nontemplate DNA and the RNA polymerase (RNAP). http://togogenome.org/gene/470934:EGO56_RS02485 ^@ http://purl.uniprot.org/uniprot/A0A0U3U6B1 ^@ Function|||Similarity|||Subunit ^@ Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.|||Belongs to the transcriptional regulatory Fis family.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS13125 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4D7 ^@ Function|||Similarity ^@ Belongs to the DtxR/MntR family.|||In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP. http://togogenome.org/gene/470934:EGO56_RS00380 ^@ http://purl.uniprot.org/uniprot/A0A7U5TYS7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS08375 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q7I9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS13935 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS03890 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1H8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbC subfamily.|||Periplasm|||Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. http://togogenome.org/gene/470934:EGO56_RS09940 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3H1 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/470934:EGO56_RS14060 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q555 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/470934:EGO56_RS13540 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4G2 ^@ Similarity ^@ Belongs to the ModE family. http://togogenome.org/gene/470934:EGO56_RS13065 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS19595 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B355 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS02310 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9G4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/470934:EGO56_RS04000 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2V6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS16135 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5B7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS06335 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y296 ^@ Function|||Similarity ^@ Belongs to the esterase D family.|||Serine hydrolase involved in the detoxification of formaldehyde. http://togogenome.org/gene/470934:EGO56_RS02115 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS13795 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4H7 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/470934:EGO56_RS15870 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2D5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS13050 ^@ http://purl.uniprot.org/uniprot/A0A7U4TB59 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/470934:EGO56_RS10570 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3F4 ^@ Function ^@ Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil. http://togogenome.org/gene/470934:EGO56_RS02085 ^@ http://purl.uniprot.org/uniprot/A0A7U4QAL1 ^@ Similarity ^@ Belongs to the UPF0270 family. http://togogenome.org/gene/470934:EGO56_RS17930 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6C9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).|||Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Cell membrane|||Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/470934:EGO56_RS18035 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q449 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/470934:EGO56_RS05435 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1M9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/470934:EGO56_RS14565 ^@ http://purl.uniprot.org/uniprot/A0A2R4J5R3 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/470934:EGO56_RS18900 ^@ http://purl.uniprot.org/uniprot/A0A1W9EQI4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/470934:EGO56_RS09305 ^@ http://purl.uniprot.org/uniprot/A0A2R4J8P4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS03190 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1W4 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.|||Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.|||Homodimer.|||In the C-terminal section; belongs to the cytidylyltransferase family.|||In the N-terminal section; belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/470934:EGO56_RS15185 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS08730 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A501SDS9 ^@ Similarity ^@ Belongs to the acetyltransferase family. YpeA subfamily. http://togogenome.org/gene/470934:EGO56_RS09480 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B183 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS07620 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1X7 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/470934:EGO56_RS00005 ^@ http://purl.uniprot.org/uniprot/A0A7Z1XZX2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/470934:EGO56_RS15645 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y599 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/470934:EGO56_RS15325 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y512 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RcsF family.|||Cell outer membrane|||Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects. http://togogenome.org/gene/470934:EGO56_RS20455 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7I3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS01570 ^@ http://purl.uniprot.org/uniprot/A0A7U4QAT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS17080 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y618 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/470934:EGO56_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B360 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS18100 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q442 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/470934:EGO56_RS13690 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4H6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/470934:EGO56_RS04440 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y192 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS05270 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1I8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/470934:EGO56_RS01830 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0C4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S54 family.|||Cell membrane|||Membrane|||Rhomboid-type serine protease that catalyzes intramembrane proteolysis. http://togogenome.org/gene/470934:EGO56_RS13010 ^@ http://purl.uniprot.org/uniprot/A0A2R4J6I7 ^@ Similarity|||Subunit ^@ Belongs to the glutaredoxin family.|||Monomer. http://togogenome.org/gene/470934:EGO56_RS16960 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7L2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase U32 family. UbiV subfamily.|||Forms an heterodimer with UbiU.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway. http://togogenome.org/gene/470934:EGO56_RS14000 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0H8 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/470934:EGO56_RS17820 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6Y3 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/470934:EGO56_RS14005 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B220 ^@ Similarity ^@ Belongs to the UPF0250 family. http://togogenome.org/gene/470934:EGO56_RS02340 ^@ http://purl.uniprot.org/uniprot/A0A0U3UMG4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/470934:EGO56_RS03295 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0Y0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS08945 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2Z3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapB family.|||Cell inner membrane|||Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane. http://togogenome.org/gene/470934:EGO56_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y181 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Monomer. http://togogenome.org/gene/470934:EGO56_RS02250 ^@ http://purl.uniprot.org/uniprot/A0A2R4J2D9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/470934:EGO56_RS02280 ^@ http://purl.uniprot.org/uniprot/A0A109YC55 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/470934:EGO56_RS01785 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0L2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS14630 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y563 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/470934:EGO56_RS08535 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3P7 ^@ Similarity ^@ Belongs to the UPF0260 family. http://togogenome.org/gene/470934:EGO56_RS02240 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9I3 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/470934:EGO56_RS06585 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1R0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS00690 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AY83 ^@ Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS11830 ^@ http://purl.uniprot.org/uniprot/A0A7U4TBB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FlgA family.|||Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.|||Periplasm http://togogenome.org/gene/470934:EGO56_RS10855 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Gram-negative porin family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS15455 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2Z0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/470934:EGO56_RS13920 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q6J3 ^@ Similarity ^@ Belongs to the UPF0053 family. http://togogenome.org/gene/470934:EGO56_RS15565 ^@ http://purl.uniprot.org/uniprot/A0A2R4J572 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. http://togogenome.org/gene/470934:EGO56_RS17005 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3M6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/470934:EGO56_RS02405 ^@ http://purl.uniprot.org/uniprot/A0A7U4QAG8 ^@ Similarity ^@ Belongs to the Smg family. http://togogenome.org/gene/470934:EGO56_RS15475 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y624 ^@ Similarity ^@ Belongs to the UPF0325 family. http://togogenome.org/gene/470934:EGO56_RS03615 ^@ http://purl.uniprot.org/uniprot/A0A109YBZ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.|||Monomer. http://togogenome.org/gene/470934:EGO56_RS15175 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5G8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS13800 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B323 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SeqA family.|||Cytoplasm|||Homodimer. Polymerizes to form helical filaments.|||Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. http://togogenome.org/gene/470934:EGO56_RS11800 ^@ http://purl.uniprot.org/uniprot/A0A120LP56 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/470934:EGO56_RS00555 ^@ http://purl.uniprot.org/uniprot/A0A7Z1XZW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/470934:EGO56_RS10215 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2E0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/470934:EGO56_RS00020 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B237 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/470934:EGO56_RS06325 ^@ http://purl.uniprot.org/uniprot/A0A501SG75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/470934:EGO56_RS05310 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B310 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M20A family. DapE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS08365 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B115 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ProQ family.|||Cytoplasm|||RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. http://togogenome.org/gene/470934:EGO56_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0G3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.|||Cell inner membrane|||Interacts with the regulatory subunit KefG.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. http://togogenome.org/gene/470934:EGO56_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2V0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/470934:EGO56_RS18320 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3V6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS10785 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3I6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS03870 ^@ http://purl.uniprot.org/uniprot/A0A7U4TBU2 ^@ Similarity ^@ Belongs to the SdhE FAD assembly factor family. http://togogenome.org/gene/470934:EGO56_RS02220 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9R4 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/470934:EGO56_RS05160 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1Q8 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/470934:EGO56_RS05800 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZ32 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.|||Methylates ribosomal protein uL3 on a specific glutamine residue. http://togogenome.org/gene/470934:EGO56_RS15680 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS08615 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2T3 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/470934:EGO56_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y169 ^@ Function|||Similarity ^@ Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.|||Catalyzes the reduction of tatronate semialdehyde to D-glycerate. http://togogenome.org/gene/470934:EGO56_RS07830 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2L8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyltransferase 20 family.|||Homotetramer.|||Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor. http://togogenome.org/gene/470934:EGO56_RS13350 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4D4 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/470934:EGO56_RS14390 ^@ http://purl.uniprot.org/uniprot/A0A2R4J5P2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/470934:EGO56_RS01815 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0C2 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/470934:EGO56_RS13910 ^@ http://purl.uniprot.org/uniprot/A0A2R4J5Y9 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/470934:EGO56_RS10550 ^@ http://purl.uniprot.org/uniprot/A0A7U4TB94 ^@ Domain|||Function|||Subunit ^@ Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.|||Homodimer.|||Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. http://togogenome.org/gene/470934:EGO56_RS14370 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4Q9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2B2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS18580 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B598 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Cell membrane|||Membrane|||Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. http://togogenome.org/gene/470934:EGO56_RS05405 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q9D2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/470934:EGO56_RS15860 ^@ http://purl.uniprot.org/uniprot/A0A2R4J521 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. FtsW subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Peptidoglycan polymerase that is essential for cell division. http://togogenome.org/gene/470934:EGO56_RS14140 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4Z0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS09190 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y325 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TtcA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.|||Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.|||Cytoplasm|||Homodimer.|||The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster. http://togogenome.org/gene/470934:EGO56_RS12515 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q5S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS16705 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6K4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/470934:EGO56_RS13975 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4Y6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/470934:EGO56_RS04460 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q9Q3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/470934:EGO56_RS04310 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q9Q9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoS subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. http://togogenome.org/gene/470934:EGO56_RS18245 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3V1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.|||Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/470934:EGO56_RS08680 ^@ http://purl.uniprot.org/uniprot/A0A109YBD1 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/470934:EGO56_RS02695 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0N9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/470934:EGO56_RS13740 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B201 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase C15 family.|||Cytoplasm|||Homotetramer.|||Removes 5-oxoproline from various penultimate amino acid residues except L-proline. http://togogenome.org/gene/470934:EGO56_RS02540 ^@ http://purl.uniprot.org/uniprot/A0A2R4J291 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/470934:EGO56_RS04875 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1L7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/470934:EGO56_RS12755 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q5P2 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/470934:EGO56_RS02800 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0U6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol monophosphatase superfamily. CysQ family.|||Cell inner membrane|||Converts adenosine-3',5'-bisphosphate (PAP) to AMP. http://togogenome.org/gene/470934:EGO56_RS03920 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y140 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS00685 ^@ http://purl.uniprot.org/uniprot/A0A501RY07 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/470934:EGO56_RS12875 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1V3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/470934:EGO56_RS02060 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0F3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||Involved in both the arginine and lysine biosynthetic pathways. http://togogenome.org/gene/470934:EGO56_RS11745 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q601 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/470934:EGO56_RS02335 ^@ http://purl.uniprot.org/uniprot/A0A109YC68 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/470934:EGO56_RS03330 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AYP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS04835 ^@ http://purl.uniprot.org/uniprot/A0A7U4TCT2 ^@ Function ^@ Acts as a radical domain for damaged PFL and possibly other radical proteins. http://togogenome.org/gene/470934:EGO56_RS04375 ^@ http://purl.uniprot.org/uniprot/A0A7U4TC74 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS02110 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AYH7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS15005 ^@ http://purl.uniprot.org/uniprot/A0A109YAJ1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/470934:EGO56_RS05935 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y223 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2N8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhC family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers. http://togogenome.org/gene/470934:EGO56_RS16750 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B501 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraB family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.|||Interacts with the C-terminal region of Rne. http://togogenome.org/gene/470934:EGO56_RS04885 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1D1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS20580 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7K0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/470934:EGO56_RS05995 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q948 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/470934:EGO56_RS18485 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6E4 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/470934:EGO56_RS11095 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4K9 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/470934:EGO56_RS05450 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1Y2 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/470934:EGO56_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0L0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/470934:EGO56_RS00590 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B275 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.|||Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(acyl)-lipid IV(A).|||Cell inner membrane http://togogenome.org/gene/470934:EGO56_RS17020 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B110 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/470934:EGO56_RS14345 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6R4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS11805 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2P6 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/470934:EGO56_RS05740 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1V7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/470934:EGO56_RS15430 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5E3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS03410 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AYQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/470934:EGO56_RS05195 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B5D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS16930 ^@ http://purl.uniprot.org/uniprot/A0A7U4TA98 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/470934:EGO56_RS12800 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1U6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS04830 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1U4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/470934:EGO56_RS15055 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y507 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Gram-negative porin family.|||Cell outer membrane|||Homotrimer.|||Membrane http://togogenome.org/gene/470934:EGO56_RS13185 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS10610 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3Q2 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/470934:EGO56_RS15935 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3F3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/470934:EGO56_RS14710 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q6A3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/470934:EGO56_RS05795 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1T9 ^@ Similarity ^@ Belongs to the UPF0115 family. http://togogenome.org/gene/470934:EGO56_RS05925 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1R1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS02765 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9B2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/470934:EGO56_RS10615 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6G2 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/470934:EGO56_RS17850 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6C1 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/470934:EGO56_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0R1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS14475 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q506 ^@ Similarity ^@ Belongs to the Hha/YmoA/Cnu family. http://togogenome.org/gene/470934:EGO56_RS13635 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q6M3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CpoB family.|||Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.|||Periplasm http://togogenome.org/gene/470934:EGO56_RS11790 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y439 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/470934:EGO56_RS20005 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y702 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS15410 ^@ http://purl.uniprot.org/uniprot/A0A2R4J5A1 ^@ Similarity ^@ Belongs to the skp family. http://togogenome.org/gene/470934:EGO56_RS18570 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6N7 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/470934:EGO56_RS06195 ^@ http://purl.uniprot.org/uniprot/A0A109YCD8 ^@ Similarity ^@ Belongs to the UPF0352 family. http://togogenome.org/gene/470934:EGO56_RS11030 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q7I8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS00300 ^@ http://purl.uniprot.org/uniprot/A0A0U3V4W4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/470934:EGO56_RS00780 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0Z5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer. http://togogenome.org/gene/470934:EGO56_RS02875 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0V9 ^@ Function|||Similarity ^@ Belongs to the peptidase U62 family.|||Probable metalloprotease. http://togogenome.org/gene/470934:EGO56_RS11410 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2S8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS17235 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y611 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptA family.|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.|||Periplasm http://togogenome.org/gene/470934:EGO56_RS03710 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1F7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/470934:EGO56_RS04630 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q9P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS07560 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q7U4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/470934:EGO56_RS18525 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y662 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. RhlB subfamily.|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA. http://togogenome.org/gene/470934:EGO56_RS06270 ^@ http://purl.uniprot.org/uniprot/A0A2R4JA97 ^@ Similarity ^@ Belongs to the elongation factor P family. http://togogenome.org/gene/470934:EGO56_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A7U4TCZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/470934:EGO56_RS10060 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZU3 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/470934:EGO56_RS18845 ^@ http://purl.uniprot.org/uniprot/A0A2R4J3I6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/470934:EGO56_RS02710 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0N3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease.|||Membrane http://togogenome.org/gene/470934:EGO56_RS10625 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3R0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/470934:EGO56_RS16710 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5I4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/470934:EGO56_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y005 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic sulfate-binding protein family.|||Periplasm http://togogenome.org/gene/470934:EGO56_RS15890 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q4U4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Membrane|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/470934:EGO56_RS08930 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2U9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS11760 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3Y7 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/470934:EGO56_RS14500 ^@ http://purl.uniprot.org/uniprot/A0A7U4TA26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS07565 ^@ http://purl.uniprot.org/uniprot/A0A2R4JCI1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/470934:EGO56_RS05905 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q931 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS08215 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2Q5 ^@ Similarity|||Subunit ^@ Belongs to the KHG/KDPG aldolase family.|||Homotrimer. http://togogenome.org/gene/470934:EGO56_RS10210 ^@ http://purl.uniprot.org/uniprot/A0A1W9EX85 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/470934:EGO56_RS01555 ^@ http://purl.uniprot.org/uniprot/A0A501S2E7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/470934:EGO56_RS04390 ^@ http://purl.uniprot.org/uniprot/A0A1W9ERQ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/470934:EGO56_RS13555 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0F3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q8C7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0259 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS00045 ^@ http://purl.uniprot.org/uniprot/A0A501S3B6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.|||Belongs to the small heat shock protein (HSP20) family.|||Cytoplasm|||Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations. http://togogenome.org/gene/470934:EGO56_RS18710 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y667 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/470934:EGO56_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q4V5 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q8D9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/470934:EGO56_RS02350 ^@ http://purl.uniprot.org/uniprot/A0A1W9EMP0 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/470934:EGO56_RS02285 ^@ http://purl.uniprot.org/uniprot/A0A0X8QAF9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/470934:EGO56_RS06135 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1Z9 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/470934:EGO56_RS02230 ^@ http://purl.uniprot.org/uniprot/A0A501S4A4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/470934:EGO56_RS18685 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y679 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/470934:EGO56_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q3M0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/470934:EGO56_RS15480 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y533 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/470934:EGO56_RS15470 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y556 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/470934:EGO56_RS08125 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3I8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.|||Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS04110 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1A5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.|||Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.|||Cytoplasm|||Monomer. http://togogenome.org/gene/470934:EGO56_RS13020 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B331 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS09995 ^@ http://purl.uniprot.org/uniprot/A0A1W9EZN9 ^@ Function|||Similarity ^@ Belongs to the PqqA family.|||Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide. http://togogenome.org/gene/470934:EGO56_RS07535 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3D9 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/470934:EGO56_RS03620 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y118 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/470934:EGO56_RS00480 ^@ http://purl.uniprot.org/uniprot/A0A5K4Z0Q8 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. http://togogenome.org/gene/470934:EGO56_RS02690 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZZ1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/470934:EGO56_RS02215 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9W2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/470934:EGO56_RS02700 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1R3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/470934:EGO56_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3L6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS12790 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B317 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS14415 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0K4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS02275 ^@ http://purl.uniprot.org/uniprot/A0A0U3TEH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/470934:EGO56_RS05345 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1R6 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/470934:EGO56_RS00460 ^@ http://purl.uniprot.org/uniprot/A0A7Z1XZV4 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/470934:EGO56_RS15315 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q5X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS06200 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0N9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/470934:EGO56_RS05770 ^@ http://purl.uniprot.org/uniprot/A0A7U4TCD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OmpP1/FadL family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS05275 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q9K3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamC family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/470934:EGO56_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0T5 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/470934:EGO56_RS10825 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1G3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/470934:EGO56_RS12725 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1U2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MukE family.|||Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.|||Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.|||nucleoid http://togogenome.org/gene/470934:EGO56_RS13570 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5H6 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/470934:EGO56_RS03650 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1G2 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/470934:EGO56_RS10340 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3H0 ^@ Similarity ^@ Belongs to the peptidase S24 family. http://togogenome.org/gene/470934:EGO56_RS10600 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3K3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.|||Belongs to the Lpp family.|||Cell outer membrane|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||cell wall http://togogenome.org/gene/470934:EGO56_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1T1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS15085 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4Y8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS06565 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y275 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS07895 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2K3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CheZ family.|||Cytoplasm|||Homodimer.|||Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). http://togogenome.org/gene/470934:EGO56_RS12575 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y443 ^@ Caution|||Function|||Induction|||PTM|||Similarity|||Subunit ^@ Belongs to the SulA family.|||By DNA damage, as part of the SOS response.|||Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.|||Interacts with FtsZ.|||Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS12840 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q5R9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolA family.|||Monomer.|||Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).|||Periplasm http://togogenome.org/gene/470934:EGO56_RS17305 ^@ http://purl.uniprot.org/uniprot/A0A109YA98 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/470934:EGO56_RS17225 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5Q5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the KdsC family.|||Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS06770 ^@ http://purl.uniprot.org/uniprot/A0A501SGG0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.|||Feedback inhibited by histidine. http://togogenome.org/gene/470934:EGO56_RS18250 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3X5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/470934:EGO56_RS11825 ^@ http://purl.uniprot.org/uniprot/A0A501SHX5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/470934:EGO56_RS15835 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5M3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/470934:EGO56_RS17215 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5Q6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS00350 ^@ http://purl.uniprot.org/uniprot/A0A7Z1XZU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell membrane|||Membrane|||Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter. http://togogenome.org/gene/470934:EGO56_RS04905 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1S9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/470934:EGO56_RS07835 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2G2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhD family.|||Cytoplasm|||Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.|||The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA. http://togogenome.org/gene/470934:EGO56_RS09125 ^@ http://purl.uniprot.org/uniprot/A0A7U4TBW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS14770 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y591 ^@ Function ^@ Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals. http://togogenome.org/gene/470934:EGO56_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2P3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/470934:EGO56_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A1W9ES74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0391 family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS16065 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5P7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/470934:EGO56_RS11740 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1M8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/470934:EGO56_RS17365 ^@ http://purl.uniprot.org/uniprot/A0A2R4J4A3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/470934:EGO56_RS02720 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0T3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/470934:EGO56_RS12885 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y595 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/470934:EGO56_RS08425 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3J2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y012 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraA family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.|||Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB. http://togogenome.org/gene/470934:EGO56_RS13985 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B332 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. MrdA subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall.|||Cell inner membrane http://togogenome.org/gene/470934:EGO56_RS21180 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7E3 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/470934:EGO56_RS15620 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0T0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm|||Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine. http://togogenome.org/gene/470934:EGO56_RS05360 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1M1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS04005 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y149 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS05190 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1H9 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/470934:EGO56_RS01020 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y028 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS00235 ^@ http://purl.uniprot.org/uniprot/A0A7Z1XZZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. http://togogenome.org/gene/470934:EGO56_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A2R4J924 ^@ Function|||Similarity|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ. http://togogenome.org/gene/470934:EGO56_RS08700 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q896 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/470934:EGO56_RS15840 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q5T5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/470934:EGO56_RS17760 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y682 ^@ Similarity ^@ Belongs to the transposase 8 family. http://togogenome.org/gene/470934:EGO56_RS00305 ^@ http://purl.uniprot.org/uniprot/A0A2R4J3B7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/470934:EGO56_RS04075 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AYU9 ^@ Function ^@ Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. http://togogenome.org/gene/470934:EGO56_RS17060 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5M6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS06005 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1S1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cell membrane|||In the C-terminal section; belongs to the complex I 49 kDa subunit family.|||In the N-terminal section; belongs to the complex I 30 kDa subunit family.|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/470934:EGO56_RS20540 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7R4 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS03145 ^@ http://purl.uniprot.org/uniprot/A0A109YC35 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/470934:EGO56_RS08120 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2J5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.|||Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS18085 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y623 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/470934:EGO56_RS02010 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS18400 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B589 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS06285 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1X2 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/470934:EGO56_RS16130 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5G7 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/470934:EGO56_RS07500 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2H0 ^@ Function|||Similarity ^@ Belongs to the vsr family.|||May nick specific sequences that contain T:G mispairs resulting from m5C-deamination. http://togogenome.org/gene/470934:EGO56_RS06055 ^@ http://purl.uniprot.org/uniprot/A0A501SEH2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/470934:EGO56_RS14680 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4V5 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/470934:EGO56_RS15405 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y569 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/470934:EGO56_RS13820 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4K4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS07365 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2L7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1I8 ^@ Similarity ^@ Belongs to the GppA/Ppx family. http://togogenome.org/gene/470934:EGO56_RS11795 ^@ http://purl.uniprot.org/uniprot/A0A7U4TBN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family.|||Cell outer membrane|||Membrane|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/470934:EGO56_RS01405 ^@ http://purl.uniprot.org/uniprot/A0A501S7E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS04285 ^@ http://purl.uniprot.org/uniprot/A0A2R4JCG8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/470934:EGO56_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0W5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/470934:EGO56_RS09030 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2V6 ^@ Function|||Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.|||Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis. http://togogenome.org/gene/470934:EGO56_RS15155 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y555 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS15725 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6I6 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/470934:EGO56_RS02990 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS15110 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3A0 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/470934:EGO56_RS20145 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4D9 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/470934:EGO56_RS15265 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4Q9 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/470934:EGO56_RS11650 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2U3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.|||Cytoplasm|||Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. http://togogenome.org/gene/470934:EGO56_RS02180 ^@ http://purl.uniprot.org/uniprot/A0A120LPQ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/470934:EGO56_RS05545 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q9A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS17885 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PsiE family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS01895 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1B7 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/470934:EGO56_RS02930 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0R7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y282 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily. http://togogenome.org/gene/470934:EGO56_RS20895 ^@ http://purl.uniprot.org/uniprot/A0A7U4T9D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS02490 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y107 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusB subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/470934:EGO56_RS06070 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1V8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS13850 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q6M0 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/470934:EGO56_RS06035 ^@ http://purl.uniprot.org/uniprot/A0A2R4JAA2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/470934:EGO56_RS02295 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9V2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/470934:EGO56_RS18110 ^@ http://purl.uniprot.org/uniprot/A0A1W9EMM2 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/470934:EGO56_RS12595 ^@ http://purl.uniprot.org/uniprot/A0A2R4J6M4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thioester dehydratase family. FabA subfamily.|||Cytoplasm|||Homodimer.|||Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. http://togogenome.org/gene/470934:EGO56_RS01695 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0C8 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/470934:EGO56_RS11835 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q763 ^@ Function|||Similarity ^@ Belongs to the FlgM family.|||Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. http://togogenome.org/gene/470934:EGO56_RS05990 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1R4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS17245 ^@ http://purl.uniprot.org/uniprot/A0A7U4T9J6 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/470934:EGO56_RS12600 ^@ http://purl.uniprot.org/uniprot/A0A1W9EYQ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ribosome modulation factor family.|||Cytoplasm|||During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes). http://togogenome.org/gene/470934:EGO56_RS14725 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0M2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/470934:EGO56_RS04855 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q9I7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/470934:EGO56_RS05810 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1P7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M74 family.|||Binds 2 Zn(2+) ions per subunit. Zn(2+) ion 1 is bound in the active site. Zn(2+) ion 2 is bound at the dimer interface by residues from both subunits.|||Dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.|||Periplasm http://togogenome.org/gene/470934:EGO56_RS13700 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4I0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/470934:EGO56_RS02835 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9A2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/470934:EGO56_RS03525 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS07730 ^@ http://purl.uniprot.org/uniprot/A0A2R4J9E9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sigma-70 factor family. FliA subfamily.|||Cytoplasm|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. http://togogenome.org/gene/470934:EGO56_RS06090 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y250 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/470934:EGO56_RS14835 ^@ http://purl.uniprot.org/uniprot/A0A7U4TAW6 ^@ Function|||Similarity ^@ Belongs to the nucleoside phosphorylase PpnP family.|||Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. http://togogenome.org/gene/470934:EGO56_RS13640 ^@ http://purl.uniprot.org/uniprot/A0A2R4J665 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/470934:EGO56_RS04930 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AYY3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase Slt family.|||Cell outer membrane|||In the C-terminal section; belongs to the transglycosylase Slt family.|||In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.|||The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain. http://togogenome.org/gene/470934:EGO56_RS17075 ^@ http://purl.uniprot.org/uniprot/A0A5K4YWI4 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/470934:EGO56_RS17935 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y680 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/470934:EGO56_RS05950 ^@ http://purl.uniprot.org/uniprot/A0A2R4JAD0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/470934:EGO56_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A109YC81 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/470934:EGO56_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A7U4TBX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS02080 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0N7 ^@ Similarity ^@ Belongs to the phosphoribulokinase family. http://togogenome.org/gene/470934:EGO56_RS04050 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1D5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetyltransferase family. ArgA subfamily.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/470934:EGO56_RS10665 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1F3 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/470934:EGO56_RS08860 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3T3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/470934:EGO56_RS07165 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y281 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS10525 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3P2 ^@ Cofactor|||Similarity ^@ Belongs to the glyoxalase I family.|||Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits. http://togogenome.org/gene/470934:EGO56_RS10475 ^@ http://purl.uniprot.org/uniprot/A0A5K4YYB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SlyA family.|||Homodimer.|||Transcription regulator that can specifically activate or repress expression of target genes. http://togogenome.org/gene/470934:EGO56_RS18275 ^@ http://purl.uniprot.org/uniprot/A0A120LNS4 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/470934:EGO56_RS15850 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4U4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS14270 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5N2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/470934:EGO56_RS02305 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9T7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/470934:EGO56_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0K5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GlpE family.|||Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS12675 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4A2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS18515 ^@ http://purl.uniprot.org/uniprot/A0A2R4J3N9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure. http://togogenome.org/gene/470934:EGO56_RS16290 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5F7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein bS18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS08840 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2B7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/470934:EGO56_RS05910 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1Q3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS00250 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B252 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/470934:EGO56_RS04965 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1D9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS04675 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0E0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS15990 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5N8 ^@ Domain|||Function|||Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Homodimer.|||Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.|||The transmembrane domain is a dimerization domain. http://togogenome.org/gene/470934:EGO56_RS10575 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3J1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Multidrug efflux pump that functions probably as a Na(+)/drug antiporter. http://togogenome.org/gene/470934:EGO56_RS20605 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y781 ^@ Similarity ^@ Belongs to the sterol desaturase family. http://togogenome.org/gene/470934:EGO56_RS08755 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B251 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS04995 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2Z3 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/470934:EGO56_RS00445 ^@ http://purl.uniprot.org/uniprot/A0A7U4TA03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbA subfamily.|||Periplasm http://togogenome.org/gene/470934:EGO56_RS01030 ^@ http://purl.uniprot.org/uniprot/A0A7U4TA97 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. http://togogenome.org/gene/470934:EGO56_RS00245 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y009 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS15800 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y592 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapD family.|||Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.|||Cytoplasm|||Interacts with FtsZ. http://togogenome.org/gene/470934:EGO56_RS13660 ^@ http://purl.uniprot.org/uniprot/A0A2R4J618 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbB/TolQ family.|||Cell inner membrane|||Membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/470934:EGO56_RS19855 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y701 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS16030 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5B8 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/470934:EGO56_RS05960 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZ39 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/470934:EGO56_RS12560 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1S9 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/470934:EGO56_RS09515 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y374 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/470934:EGO56_RS09255 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3Y3 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/470934:EGO56_RS08940 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q878 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapA family.|||Cell inner membrane|||Involved in the assembly of lipopolysaccharide (LPS).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS14360 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4P4 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. http://togogenome.org/gene/470934:EGO56_RS16270 ^@ http://purl.uniprot.org/uniprot/A0A2R4J4Q8 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/470934:EGO56_RS15400 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q4Z7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/470934:EGO56_RS09165 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B162 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/470934:EGO56_RS05280 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1L2 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/470934:EGO56_RS01135 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y038 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS12020 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3Y6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS00995 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AYA5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS11580 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1L9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/470934:EGO56_RS10705 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q7G9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/470934:EGO56_RS06000 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1T9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/470934:EGO56_RS16000 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5U8 ^@ Domain|||Function|||Subcellular Location Annotation ^@ Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.|||Periplasm|||The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition. http://togogenome.org/gene/470934:EGO56_RS16815 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5J2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.|||Cell inner membrane http://togogenome.org/gene/470934:EGO56_RS19585 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS03925 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y141 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS13655 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7J2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/470934:EGO56_RS14315 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y519 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the band 7/mec-2 family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS13855 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4X6 ^@ Cofactor ^@ Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/470934:EGO56_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A2R4J308 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/470934:EGO56_RS11060 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3V8 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/470934:EGO56_RS10595 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3F9 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/470934:EGO56_RS06355 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZ68 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/470934:EGO56_RS17780 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6E8 ^@ Function|||Subunit ^@ Homotetramer.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/470934:EGO56_RS17800 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q566 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/470934:EGO56_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A501SE15 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/470934:EGO56_RS10695 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3G9 ^@ Function|||Similarity ^@ Belongs to the glutathione peroxidase family. BtuE subfamily.|||Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. http://togogenome.org/gene/470934:EGO56_RS21635 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7L7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2P2 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS17240 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y678 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/470934:EGO56_RS06010 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y217 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/470934:EGO56_RS17185 ^@ http://purl.uniprot.org/uniprot/A0A2R4J4F9 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/470934:EGO56_RS11725 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2N9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS10965 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3U5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS14575 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0L3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/470934:EGO56_RS01880 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AYG1 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/470934:EGO56_RS15445 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3C0 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS02775 ^@ http://purl.uniprot.org/uniprot/A0A0U3U4B5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/470934:EGO56_RS06110 ^@ http://purl.uniprot.org/uniprot/A0A5K4ZPF6 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the RcsB family.|||Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.|||Interacts with RcsD.|||Phosphorylated and activated by RcsD. http://togogenome.org/gene/470934:EGO56_RS11035 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3Q7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS11820 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1N4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/470934:EGO56_RS06040 ^@ http://purl.uniprot.org/uniprot/A0A120LPH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/470934:EGO56_RS03790 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1G9 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/470934:EGO56_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0U4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS14605 ^@ http://purl.uniprot.org/uniprot/A0A7U4TB84 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane|||The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains. http://togogenome.org/gene/470934:EGO56_RS01910 ^@ http://purl.uniprot.org/uniprot/A0A7U4QAM8 ^@ Similarity ^@ Belongs to the HSP15 family. http://togogenome.org/gene/470934:EGO56_RS06740 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1S0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/470934:EGO56_RS15330 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y557 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/470934:EGO56_RS02475 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS12470 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B091 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS12625 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B306 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RlmKL family.|||Cytoplasm|||Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. http://togogenome.org/gene/470934:EGO56_RS18200 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y616 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TrkH potassium transport family.|||Cell inner membrane|||Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.|||Membrane http://togogenome.org/gene/470934:EGO56_RS00870 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q3J6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS07880 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2G3 ^@ Function ^@ Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. http://togogenome.org/gene/470934:EGO56_RS17180 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3Q9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS08175 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B213 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS10280 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3L9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS02150 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0I6 ^@ Similarity ^@ Belongs to the SlyX family. http://togogenome.org/gene/470934:EGO56_RS13195 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5C8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS18210 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y629 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.|||Binds 2 manganese ions per subunit.|||Splits dipeptides with a prolyl residue in the C-terminal position. http://togogenome.org/gene/470934:EGO56_RS02205 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0Q6 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/470934:EGO56_RS17865 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B570 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/470934:EGO56_RS12430 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y476 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS03510 ^@ http://purl.uniprot.org/uniprot/A0A7U4QA11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyl hydrolase 37 family.|||Cytoplasm|||Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.|||Monomer. http://togogenome.org/gene/470934:EGO56_RS13110 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4B6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS15940 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3J6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/470934:EGO56_RS06485 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y267 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS03285 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0W1 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/470934:EGO56_RS02510 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B198 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/470934:EGO56_RS11605 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/470934:EGO56_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZ11 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/470934:EGO56_RS14445 ^@ http://purl.uniprot.org/uniprot/A0A7U5TXD9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/470934:EGO56_RS02600 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZY5 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/470934:EGO56_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1D3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.|||Homohexamer; trimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS09240 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q877 ^@ Similarity ^@ Belongs to the peptidase S1B family. http://togogenome.org/gene/470934:EGO56_RS13990 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6G8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/470934:EGO56_RS03720 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2R6 ^@ Function|||Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.|||Catalyzes the biosynthesis of agmatine from arginine. http://togogenome.org/gene/470934:EGO56_RS05980 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2T2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 5DNU family.|||Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS00080 ^@ http://purl.uniprot.org/uniprot/A0A7U4TA27 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/470934:EGO56_RS11840 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y400 ^@ Function|||Similarity ^@ Belongs to the FlgN family.|||Required for the efficient initiation of filament assembly. http://togogenome.org/gene/470934:EGO56_RS16700 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5K0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/470934:EGO56_RS00835 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0S9 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/470934:EGO56_RS01550 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0P1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcrB family.|||Cell membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered. http://togogenome.org/gene/470934:EGO56_RS04300 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q9V8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS10830 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3I3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.|||Binds 1 zinc ion per subunit.|||Transforms N(2)-succinylglutamate into succinate and glutamate. http://togogenome.org/gene/470934:EGO56_RS17010 ^@ http://purl.uniprot.org/uniprot/A0A2R4J4D9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/470934:EGO56_RS04615 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1B5 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/470934:EGO56_RS10960 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3T9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS09200 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y337 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS01850 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0K4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NfuA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.|||Homodimer.|||Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. http://togogenome.org/gene/470934:EGO56_RS02300 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0K9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/470934:EGO56_RS07570 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3C1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliO/MopB family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS12780 ^@ http://purl.uniprot.org/uniprot/A0A120LP41 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/470934:EGO56_RS18670 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3Z8 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS14560 ^@ http://purl.uniprot.org/uniprot/A0A2R4J5L3 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/470934:EGO56_RS16225 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5R7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS19825 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1Q7 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/470934:EGO56_RS12925 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4J2 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/470934:EGO56_RS18780 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y691 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/470934:EGO56_RS13160 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS07605 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2M3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliH family.|||Cytoplasm|||Needed for flagellar regrowth and assembly. http://togogenome.org/gene/470934:EGO56_RS06330 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y273 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS01600 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0H9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell inner membrane|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/470934:EGO56_RS11375 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q7D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS09990 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q7V4 ^@ Function|||Similarity ^@ Belongs to the PqqB family.|||May be involved in the transport of PQQ or its precursor to the periplasm. http://togogenome.org/gene/470934:EGO56_RS03530 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y139 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS18155 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B178 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS18090 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y617 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/470934:EGO56_RS11530 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q7C9 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/470934:EGO56_RS17380 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y658 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. http://togogenome.org/gene/470934:EGO56_RS15595 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5F8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/470934:EGO56_RS18875 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y685 ^@ Function|||Similarity ^@ Belongs to the nitroreductase family. HadB/RutE subfamily.|||May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted. http://togogenome.org/gene/470934:EGO56_RS07745 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2K9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/470934:EGO56_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B298 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/470934:EGO56_RS02330 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B190 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/470934:EGO56_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y109 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS16410 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS18500 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3W8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family.|||Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS13900 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4X1 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/470934:EGO56_RS17165 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q520 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/470934:EGO56_RS16260 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0X2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/470934:EGO56_RS14250 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3A4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS15885 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y587 ^@ Function|||Similarity ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. http://togogenome.org/gene/470934:EGO56_RS15495 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y593 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.|||Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS18050 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3U1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS11040 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q7H8 ^@ Similarity ^@ Belongs to the UPF0162 family. http://togogenome.org/gene/470934:EGO56_RS15590 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5J1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/470934:EGO56_RS17845 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5Y5 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/470934:EGO56_RS01410 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B120 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein B family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS01390 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0M2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/470934:EGO56_RS08795 ^@ http://purl.uniprot.org/uniprot/A0A2R4J8X3 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/470934:EGO56_RS14995 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y534 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/470934:EGO56_RS05530 ^@ http://purl.uniprot.org/uniprot/A0A7U4TC19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS17315 ^@ http://purl.uniprot.org/uniprot/A0A109YA93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZapG family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS18410 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3Y4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-1 family.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS16080 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q4C7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/470934:EGO56_RS02245 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9J1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/470934:EGO56_RS01725 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B146 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS16040 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5A6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/470934:EGO56_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1K4 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/470934:EGO56_RS13940 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4J7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS06095 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y269 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/470934:EGO56_RS03835 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y243 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/470934:EGO56_RS13815 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B208 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/470934:EGO56_RS15450 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3H2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A7U4QAK1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/470934:EGO56_RS03305 ^@ http://purl.uniprot.org/uniprot/A0A7U4TCD5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/470934:EGO56_RS12945 ^@ http://purl.uniprot.org/uniprot/A0A501SET4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS15070 ^@ http://purl.uniprot.org/uniprot/A0A2R4J5C9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.|||Cell membrane|||Homotetramer.|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine. http://togogenome.org/gene/470934:EGO56_RS13460 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4S6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/470934:EGO56_RS05440 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q8J5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/470934:EGO56_RS14295 ^@ http://purl.uniprot.org/uniprot/A0A501SK94 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS18045 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B575 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/470934:EGO56_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AYP2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS03765 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y116 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LysE/ArgO transporter (TC 2.A.75) family.|||Cell membrane|||Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.|||Membrane http://togogenome.org/gene/470934:EGO56_RS04955 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q8F5 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/470934:EGO56_RS17025 ^@ http://purl.uniprot.org/uniprot/A0A501S7N5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/470934:EGO56_RS22260 ^@ http://purl.uniprot.org/uniprot/A0A501SD93 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/470934:EGO56_RS08470 ^@ http://purl.uniprot.org/uniprot/A0A501SJD1 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/470934:EGO56_RS07040 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y270 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS11540 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3S2 ^@ Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudJ subfamily.|||Monomer. http://togogenome.org/gene/470934:EGO56_RS15320 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q632 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS04205 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1L9 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS13145 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4M6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Dps family.|||Cytoplasm|||During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.|||Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited. http://togogenome.org/gene/470934:EGO56_RS06145 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1W5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/470934:EGO56_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A2R4JAB0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/470934:EGO56_RS13715 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4U8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. http://togogenome.org/gene/470934:EGO56_RS02260 ^@ http://purl.uniprot.org/uniprot/A0A120LPP9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/470934:EGO56_RS02815 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y147 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS14675 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4X8 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/470934:EGO56_RS04490 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0D2 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS20310 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4F0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/470934:EGO56_RS13665 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1Z8 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/470934:EGO56_RS04465 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1N9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/470934:EGO56_RS17715 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3U2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS20510 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y762 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS08770 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B137 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.|||Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS17000 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q4N5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/470934:EGO56_RS17725 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/470934:EGO56_RS08200 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3J8 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/470934:EGO56_RS06220 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS04670 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AYW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS09210 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y379 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/470934:EGO56_RS09985 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y465 ^@ Function|||Similarity ^@ Belongs to the PqqC family.|||Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ. http://togogenome.org/gene/470934:EGO56_RS03470 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y175 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/470934:EGO56_RS11645 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2N4 ^@ Similarity ^@ Belongs to the UPF0227 family. http://togogenome.org/gene/470934:EGO56_RS22185 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4U0 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/470934:EGO56_RS10725 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q6N0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/470934:EGO56_RS03670 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y222 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/470934:EGO56_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B294 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS04220 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1K1 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/470934:EGO56_RS15030 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4P7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 24 family. http://togogenome.org/gene/470934:EGO56_RS13710 ^@ http://purl.uniprot.org/uniprot/A0A7U4TAT1 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/470934:EGO56_RS10275 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3L5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the pyridoxine kinase family. PdxY subfamily.|||Homodimer.|||Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. http://togogenome.org/gene/470934:EGO56_RS07580 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2I0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/470934:EGO56_RS18520 ^@ http://purl.uniprot.org/uniprot/A0A109YA48 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/470934:EGO56_RS14625 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q6E0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS14755 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q6A1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell inner membrane|||Component of the transport system for branched-chain amino acids.|||Membrane http://togogenome.org/gene/470934:EGO56_RS13060 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4F2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS13100 ^@ http://purl.uniprot.org/uniprot/A0A109YAT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/470934:EGO56_RS06390 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y200 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese.|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS07125 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2F2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/470934:EGO56_RS09440 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y321 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.|||Cell membrane|||Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.|||Membrane http://togogenome.org/gene/470934:EGO56_RS17350 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6S8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.|||May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA. http://togogenome.org/gene/470934:EGO56_RS09035 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q8A1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS06645 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2A6 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/470934:EGO56_RS10685 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3G7 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/470934:EGO56_RS08580 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3K2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.|||Cell membrane|||K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels. http://togogenome.org/gene/470934:EGO56_RS13565 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q5B6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS02290 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9H2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/470934:EGO56_RS15270 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0294 family.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS00285 ^@ http://purl.uniprot.org/uniprot/A0A2R4J3C5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/470934:EGO56_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q765 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/470934:EGO56_RS16120 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5G1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/470934:EGO56_RS11785 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y448 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.|||In the C-terminal section; belongs to the glycosyl hydrolase 73 family.|||In the N-terminal section; belongs to the FlgJ family.|||Periplasm http://togogenome.org/gene/470934:EGO56_RS14495 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3B8 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/470934:EGO56_RS03990 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y266 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/470934:EGO56_RS14600 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4W8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/470934:EGO56_RS18475 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y646 ^@ Function|||Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family.|||Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate. http://togogenome.org/gene/470934:EGO56_RS01210 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q4F4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/470934:EGO56_RS00280 ^@ http://purl.uniprot.org/uniprot/A0A2R4J3B9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/470934:EGO56_RS12520 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y442 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dsrC/tusE family.|||Cytoplasm|||Interacts with the TusBCD complex. Interacts with MnmA.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD. http://togogenome.org/gene/470934:EGO56_RS14830 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y500 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/470934:EGO56_RS00390 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0A6 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/470934:EGO56_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y031 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/470934:EGO56_RS15605 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4S8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS13445 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4E2 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/470934:EGO56_RS15490 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y560 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dGTPase family. Type 1 subfamily.|||Homotetramer.|||dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs. http://togogenome.org/gene/470934:EGO56_RS02325 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9H8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/470934:EGO56_RS14340 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B235 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/470934:EGO56_RS14875 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B438 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/470934:EGO56_RS17220 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5W3 ^@ Similarity|||Subunit ^@ Belongs to the SIS family. GutQ/KpsF subfamily.|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS12980 ^@ http://purl.uniprot.org/uniprot/A0A7U4TB97 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/470934:EGO56_RS04800 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1C3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/470934:EGO56_RS16170 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3L1 ^@ Caution|||Similarity ^@ Belongs to the phosphoglycerate mutase family. GpmB subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS15925 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5T6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS14440 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4U9 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/470934:EGO56_RS12895 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q6W2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/470934:EGO56_RS18365 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y644 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q382 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/470934:EGO56_RS10200 ^@ http://purl.uniprot.org/uniprot/A0A7U4TBB3 ^@ Similarity ^@ Belongs to the Hha/YmoA/Cnu family. http://togogenome.org/gene/470934:EGO56_RS12580 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y482 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.|||Cell outer membrane|||Membrane|||Monomer and homodimer.|||The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.|||With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. http://togogenome.org/gene/470934:EGO56_RS14800 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0M8 ^@ Function|||Similarity ^@ Belongs to the CsgG family.|||May be involved in the biogenesis of curli organelles. http://togogenome.org/gene/470934:EGO56_RS16145 ^@ http://purl.uniprot.org/uniprot/A0A7U5TZ73 ^@ Function|||Similarity ^@ Belongs to the thr operon leader peptide family.|||This protein is involved in control of the biosynthesis of threonine. http://togogenome.org/gene/470934:EGO56_RS01145 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y051 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS13840 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4J6 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).|||Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS06025 ^@ http://purl.uniprot.org/uniprot/A0A1W9EVA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/470934:EGO56_RS05060 ^@ http://purl.uniprot.org/uniprot/A0A109YBT1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/470934:EGO56_RS02480 ^@ http://purl.uniprot.org/uniprot/A0A7U4TCZ4 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/470934:EGO56_RS04825 ^@ http://purl.uniprot.org/uniprot/A0A2R4JAY4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/470934:EGO56_RS03705 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y189 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS05580 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1D6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS08570 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS02500 ^@ http://purl.uniprot.org/uniprot/A0A7U4QAG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS06865 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q7Q3 ^@ Similarity ^@ Belongs to the UPF0265 family. http://togogenome.org/gene/470934:EGO56_RS18105 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6F3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/470934:EGO56_RS04805 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1G6 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/470934:EGO56_RS16175 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0W4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the YjjX NTPase family.|||Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).|||Homodimer.|||Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/470934:EGO56_RS05970 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6D2 ^@ Similarity ^@ Belongs to the UPF0304 family. http://togogenome.org/gene/470934:EGO56_RS09980 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y372 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PqqD family.|||Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.|||Monomer. Interacts with PqqE. http://togogenome.org/gene/470934:EGO56_RS16300 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5D5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methyltransferase superfamily. RsmC family.|||Cytoplasm|||Monomer.|||Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle. http://togogenome.org/gene/470934:EGO56_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y059 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/470934:EGO56_RS15050 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B282 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS03005 ^@ http://purl.uniprot.org/uniprot/A0A2R4JC38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS18230 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6B7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiD family.|||Binds 1 prenylated FMN (prenyl-FMN) per subunit.|||Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.|||Cell membrane|||Homohexamer. http://togogenome.org/gene/470934:EGO56_RS11480 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B444 ^@ Function|||Similarity ^@ Belongs to the FumD family.|||In vitro catalyzes the addition of water to fumarate, forming malate. Cannot catalyze the reverse reaction. Cannot use the cis-isomer maleate as substrate. http://togogenome.org/gene/470934:EGO56_RS06415 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B371 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS11065 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B421 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolB family.|||Cell outer membrane|||Membrane|||Monomer.|||Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. http://togogenome.org/gene/470934:EGO56_RS09945 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3H3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS05890 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0L5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS03215 ^@ http://purl.uniprot.org/uniprot/A0A7U4QA47 ^@ Similarity ^@ Belongs to the UPF0441 family. http://togogenome.org/gene/470934:EGO56_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9G3 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/470934:EGO56_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A7U4QAR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PanZ/PanM family.|||Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.|||Interacts with PanD in the presence of CoA. http://togogenome.org/gene/470934:EGO56_RS14650 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0L8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/470934:EGO56_RS04255 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y178 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/470934:EGO56_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0V5 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/470934:EGO56_RS14610 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4Z4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/470934:EGO56_RS02465 ^@ http://purl.uniprot.org/uniprot/A0A7U4QAG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS08705 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3R6 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/470934:EGO56_RS13695 ^@ http://purl.uniprot.org/uniprot/A0A120LP23 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/470934:EGO56_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1K6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/470934:EGO56_RS08970 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y336 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KdgT transporter family.|||Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS03780 ^@ http://purl.uniprot.org/uniprot/A0A5K4Z3V2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LysR transcriptional regulatory family.|||Controls the transcription of genes involved in arginine and lysine metabolism.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS17230 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y639 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptC family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.|||Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/470934:EGO56_RS02520 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6B2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/470934:EGO56_RS12860 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2W3 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0M8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.|||Monomer.|||Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. http://togogenome.org/gene/470934:EGO56_RS01800 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B151 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MdcC family.|||Covalently binds the prosthetic group of malonate decarboxylase.|||Cytoplasm|||Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism. http://togogenome.org/gene/470934:EGO56_RS00550 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q312 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/470934:EGO56_RS00840 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0X1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/470934:EGO56_RS08170 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS00275 ^@ http://purl.uniprot.org/uniprot/A0A2R4J3D3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/470934:EGO56_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9U7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/470934:EGO56_RS05965 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0208 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS09185 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2Z8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Cell inner membrane|||Membrane|||Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake. http://togogenome.org/gene/470934:EGO56_RS03995 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1C0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS05045 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1I6 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/470934:EGO56_RS00725 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y037 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/470934:EGO56_RS08835 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B256 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/470934:EGO56_RS02035 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AYG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TsgA family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS15420 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y529 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS00270 ^@ http://purl.uniprot.org/uniprot/A0A2R4J3F3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/470934:EGO56_RS09285 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y300 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Heterodimer of an alpha and a beta chain.|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/470934:EGO56_RS02265 ^@ http://purl.uniprot.org/uniprot/A0A109YC61 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/470934:EGO56_RS06050 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1T7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4 family.|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||Membrane http://togogenome.org/gene/470934:EGO56_RS16720 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5K5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/470934:EGO56_RS17720 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q579 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/470934:EGO56_RS09045 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y353 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS20210 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7A7 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/470934:EGO56_RS05410 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1L5 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS02570 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y117 ^@ Function|||Similarity ^@ Belongs to the peptidase U62 family.|||Probable metalloprotease. http://togogenome.org/gene/470934:EGO56_RS08410 ^@ http://purl.uniprot.org/uniprot/A0A109YBE4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/470934:EGO56_RS17925 ^@ http://purl.uniprot.org/uniprot/A0A2R4J3Y1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS07575 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q8P5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliN/MopA/SpaO family.|||Cell membrane|||FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/470934:EGO56_RS02705 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0W2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/470934:EGO56_RS16150 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5M8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS00715 ^@ http://purl.uniprot.org/uniprot/A0A7Z1XZY4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/470934:EGO56_RS00965 ^@ http://purl.uniprot.org/uniprot/A0A501RXD5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MetJ family.|||Cytoplasm|||Does not bind DNA by a helix-turn-helix motif.|||Homodimer.|||This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. http://togogenome.org/gene/470934:EGO56_RS03275 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y128 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/470934:EGO56_RS00820 ^@ http://purl.uniprot.org/uniprot/A0A2R4J393 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/470934:EGO56_RS20460 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7E1 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/470934:EGO56_RS09475 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZR0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS12785 ^@ http://purl.uniprot.org/uniprot/A0A501SLQ2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/470934:EGO56_RS18740 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6H6 ^@ Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Homodimer.|||Membrane http://togogenome.org/gene/470934:EGO56_RS06595 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZ82 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/470934:EGO56_RS18745 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6Q5 ^@ Similarity ^@ Belongs to the mannitol dehydrogenase family. http://togogenome.org/gene/470934:EGO56_RS18060 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B175 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Rsd/AlgQ family.|||Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.|||Cytoplasm|||Interacts with RpoD. http://togogenome.org/gene/470934:EGO56_RS07555 ^@ http://purl.uniprot.org/uniprot/A0A7U4TCD8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/470934:EGO56_RS18380 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y637 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/470934:EGO56_RS13235 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4Q0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS13725 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B318 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b560 family.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/470934:EGO56_RS05885 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q980 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS04455 ^@ http://purl.uniprot.org/uniprot/A0A8X8DQJ9 ^@ Caution|||Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/470934:EGO56_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y334 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS15345 ^@ http://purl.uniprot.org/uniprot/A0A2R4J5B5 ^@ Similarity ^@ Belongs to the UPF0253 family. http://togogenome.org/gene/470934:EGO56_RS17465 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y671 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB). http://togogenome.org/gene/470934:EGO56_RS08520 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q8C0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/470934:EGO56_RS04180 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y164 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/470934:EGO56_RS17205 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5Q1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD). http://togogenome.org/gene/470934:EGO56_RS13730 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B375 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/470934:EGO56_RS05285 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q9D6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS02580 ^@ http://purl.uniprot.org/uniprot/A0A2R4J267 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AaeX family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS10900 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2P8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS07810 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3F1 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/470934:EGO56_RS02130 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0Q0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.|||Cell inner membrane|||Interacts with KefB.|||Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. http://togogenome.org/gene/470934:EGO56_RS18885 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6A7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/470934:EGO56_RS00290 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q3S4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/470934:EGO56_RS01040 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0A1 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.|||Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). http://togogenome.org/gene/470934:EGO56_RS18125 ^@ http://purl.uniprot.org/uniprot/A0A2R4J3T8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/470934:EGO56_RS14865 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B4N8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/470934:EGO56_RS09510 ^@ http://purl.uniprot.org/uniprot/A0A7U4QB24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS18260 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2R4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/470934:EGO56_RS14615 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q636 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/470934:EGO56_RS10810 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B2H7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS01455 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0C6 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/470934:EGO56_RS15425 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS14100 ^@ http://purl.uniprot.org/uniprot/A0A7U4QB04 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS12975 ^@ http://purl.uniprot.org/uniprot/A0A2R4J6I8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS18375 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6E9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/470934:EGO56_RS03755 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y186 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/470934:EGO56_RS02255 ^@ http://purl.uniprot.org/uniprot/A0A120LPQ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/470934:EGO56_RS10730 ^@ http://purl.uniprot.org/uniprot/A0A2R4J7S1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/470934:EGO56_RS10115 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3J5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/470934:EGO56_RS17325 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q5C5 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/470934:EGO56_RS14585 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4V0 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/470934:EGO56_RS18095 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6C4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/470934:EGO56_RS14715 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B373 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/470934:EGO56_RS12890 ^@ http://purl.uniprot.org/uniprot/A0A2R4J6G3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/470934:EGO56_RS08720 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2S0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS18220 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y620 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. Thiolase family.|||Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.|||Cytoplasm|||Heterotetramer of two alpha chains (FadB) and two beta chains (FadA). http://togogenome.org/gene/470934:EGO56_RS14430 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5Q3 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/470934:EGO56_RS07875 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0Z2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS17285 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5T7 ^@ Cofactor|||Function|||Subunit ^@ Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.|||Binds 1 FAD per subunit.|||Binds 1 FMN per subunit.|||Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. http://togogenome.org/gene/470934:EGO56_RS13980 ^@ http://purl.uniprot.org/uniprot/A0A0U3UGY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/470934:EGO56_RS00845 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AY95 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/470934:EGO56_RS03735 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AYS6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/470934:EGO56_RS20240 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q2F0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/470934:EGO56_RS14775 ^@ http://purl.uniprot.org/uniprot/A0A109YAJ9 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/470934:EGO56_RS03000 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B169 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MzrA family.|||Cell inner membrane|||Interacts with EnvZ.|||Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. http://togogenome.org/gene/470934:EGO56_RS12820 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4A7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS04840 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B1H6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. SrmB subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.|||Interacts with the 50S ribosomal subunit. http://togogenome.org/gene/470934:EGO56_RS14385 ^@ http://purl.uniprot.org/uniprot/A0A7U4TAX4 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/470934:EGO56_RS14505 ^@ http://purl.uniprot.org/uniprot/A0A109YAN8 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/470934:EGO56_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B179 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS15750 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y567 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:galactoside symporter (TC 2.A.2) family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS15830 ^@ http://purl.uniprot.org/uniprot/A0A2R4J4Z5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/470934:EGO56_RS14730 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B265 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/470934:EGO56_RS07035 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS04130 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1L0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Syd family.|||Cell inner membrane|||Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. http://togogenome.org/gene/470934:EGO56_RS17065 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6K6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/470934:EGO56_RS17330 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q5C9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.|||Homodimer.|||With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P. http://togogenome.org/gene/470934:EGO56_RS17860 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6F8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/470934:EGO56_RS18430 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y748 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Involved in a late step of protoheme IX synthesis.|||Membrane http://togogenome.org/gene/470934:EGO56_RS06750 ^@ http://purl.uniprot.org/uniprot/A0A7Z2AZ92 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/470934:EGO56_RS11355 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q7D3 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the PHP family.|||Binds 3 Zn(2+) ions per subunit.|||Homotrimer. http://togogenome.org/gene/470934:EGO56_RS01630 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0Q1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family. http://togogenome.org/gene/470934:EGO56_RS02315 ^@ http://purl.uniprot.org/uniprot/A0A0X8Q9G5 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/470934:EGO56_RS19945 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y710 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS04275 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y6A4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsB family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/470934:EGO56_RS04900 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1N3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/470934:EGO56_RS15510 ^@ http://purl.uniprot.org/uniprot/A0A2R4J582 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 1 iron-sulfur cluster per subunit.|||Homodimer.|||Required for insertion of 4Fe-4S clusters for at least IspG. http://togogenome.org/gene/470934:EGO56_RS15370 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3B5 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/470934:EGO56_RS07845 ^@ http://purl.uniprot.org/uniprot/A0A2R4J9D3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/470934:EGO56_RS20530 ^@ http://purl.uniprot.org/uniprot/A0A2R4JDW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GhoT/OrtT toxin family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/470934:EGO56_RS08545 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2U4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||Multifunctional regulator of fatty acid metabolism. http://togogenome.org/gene/470934:EGO56_RS20295 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y7B8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/470934:EGO56_RS14880 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B3E2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/470934:EGO56_RS12690 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4G1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/470934:EGO56_RS02550 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y0L3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Cell inner membrane|||Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.|||Membrane http://togogenome.org/gene/470934:EGO56_RS00885 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y024 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/470934:EGO56_RS11735 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B042 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/470934:EGO56_RS04195 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1F5 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/470934:EGO56_RS16020 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0V6 ^@ Function|||Similarity ^@ Belongs to the Ap4A hydrolase family.|||Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP. http://togogenome.org/gene/470934:EGO56_RS09690 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3F5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/470934:EGO56_RS15435 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5L6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/470934:EGO56_RS08610 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y3Q6 ^@ Function|||Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. http://togogenome.org/gene/470934:EGO56_RS15245 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y5F4 ^@ Function|||Subunit ^@ DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.|||The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau. http://togogenome.org/gene/470934:EGO56_RS01090 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q4I6 ^@ Function|||Similarity ^@ Belongs to the LysR transcriptional regulatory family.|||Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon. http://togogenome.org/gene/470934:EGO56_RS06280 ^@ http://purl.uniprot.org/uniprot/A0A7Z2B0P5 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport. http://togogenome.org/gene/470934:EGO56_RS14685 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y501 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers. http://togogenome.org/gene/470934:EGO56_RS20425 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y752 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/470934:EGO56_RS10155 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y484 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm http://togogenome.org/gene/470934:EGO56_RS06375 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q8Z4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.|||Cell inner membrane|||Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system. http://togogenome.org/gene/470934:EGO56_RS14695 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y586 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/470934:EGO56_RS05615 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q9F2 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/470934:EGO56_RS09010 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y2V7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/470934:EGO56_RS13705 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4V4 ^@ Function|||Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/470934:EGO56_RS08695 ^@ http://purl.uniprot.org/uniprot/A0A7U4Q895 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the RssB family.|||Binds to RpoS.|||Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.|||Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. http://togogenome.org/gene/470934:EGO56_RS14375 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y4W0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/470934:EGO56_RS14750 ^@ http://purl.uniprot.org/uniprot/A0A7U4TAX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/470934:EGO56_RS05765 ^@ http://purl.uniprot.org/uniprot/A0A7Z1Y1P0 ^@ Similarity ^@ Belongs to the MlaA family.