http://togogenome.org/gene/50390:LOC114335229 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8Q9 ^@ Similarity ^@ Belongs to the vir family. http://togogenome.org/gene/50390:LOC114328249 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB94|||http://purl.uniprot.org/uniprot/A0A6P7FIE1 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/50390:LOC114326593 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB93 ^@ Similarity ^@ Belongs to the TACO1 family. http://togogenome.org/gene/50390:LOC114340355 ^@ http://purl.uniprot.org/uniprot/A0A6P7GC63 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family. http://togogenome.org/gene/50390:LOC114326874 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5Y6|||http://purl.uniprot.org/uniprot/A0A6P7FCL2|||http://purl.uniprot.org/uniprot/A0A6P7FCM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF4 family.|||Nucleus http://togogenome.org/gene/50390:LOC114341884 ^@ http://purl.uniprot.org/uniprot/A0A6P7GR28 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRS1 family.|||Involved in ribosomal large subunit assembly.|||Nucleus http://togogenome.org/gene/50390:LOC114342900 ^@ http://purl.uniprot.org/uniprot/A0A6P7GVT9 ^@ Similarity ^@ Belongs to the HARBI1 family. http://togogenome.org/gene/50390:LOC114326997 ^@ http://purl.uniprot.org/uniprot/A0A6P7FD40 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114344233 ^@ http://purl.uniprot.org/uniprot/A0A6P7H4F4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/50390:LOC114332955 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0F4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL5 family. http://togogenome.org/gene/50390:LOC114330903 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJ71 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/50390:LOC114328502 ^@ http://purl.uniprot.org/uniprot/A0A6P7FC27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/50390:LOC114325106 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0P6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UTP11 family.|||Component of the ribosomal small subunit (SSU) processome.|||Involved in nucleolar processing of pre-18S ribosomal RNA.|||nucleolus http://togogenome.org/gene/50390:LOC114329344 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.|||GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.|||nucleolus http://togogenome.org/gene/50390:LOC114324746 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYS5|||http://purl.uniprot.org/uniprot/A0A6P7F0I8|||http://purl.uniprot.org/uniprot/A0A6P7F4J2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114327030 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6F7|||http://purl.uniprot.org/uniprot/A0A6P7FD88 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I family. http://togogenome.org/gene/50390:LOC114335094 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8A8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114342869 ^@ http://purl.uniprot.org/uniprot/A0A6P7GIR1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOTCH family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Nucleus http://togogenome.org/gene/50390:LOC114328448 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJA8 ^@ Similarity ^@ Belongs to the complex I 23 kDa subunit family. http://togogenome.org/gene/50390:LOC114329296 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114344555 ^@ http://purl.uniprot.org/uniprot/A0A6P7GYJ1 ^@ Similarity ^@ Belongs to the strictosidine synthase family. http://togogenome.org/gene/50390:LOC114325378 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0X8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/50390:LOC114333656 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2Z4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114327464 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEW9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114331309 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M67A family. CSN6 subfamily.|||Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.|||Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114324963 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZH8 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/50390:LOC114330321 ^@ http://purl.uniprot.org/uniprot/A0A6P7FR42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/50390:LOC114325966 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4W8 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/50390:LOC114337055 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2R6|||http://purl.uniprot.org/uniprot/A0A6P7GE72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/50390:LOC114338799 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7W6 ^@ Similarity ^@ Belongs to the splicing factor SR family. http://togogenome.org/gene/50390:LOC114333162 ^@ http://purl.uniprot.org/uniprot/A0A6P7FR31|||http://purl.uniprot.org/uniprot/A0A6P7FRA4|||http://purl.uniprot.org/uniprot/A0A6P7FRB4|||http://purl.uniprot.org/uniprot/A0A6P7FVN3|||http://purl.uniprot.org/uniprot/A0A6P7FVN8|||http://purl.uniprot.org/uniprot/A0A6P7G151|||http://purl.uniprot.org/uniprot/A0A6P7G2H0|||http://purl.uniprot.org/uniprot/A0A6P7G2H6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.|||Peroxisome http://togogenome.org/gene/50390:LOC114335162 ^@ http://purl.uniprot.org/uniprot/A0A6P7G298 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114334866 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8A7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114331340 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKY1 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/50390:LOC114334271 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUJ5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/50390:LOC114340841 ^@ http://purl.uniprot.org/uniprot/A0A6P7GN48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS3 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114342748 ^@ http://purl.uniprot.org/uniprot/A0A6P7GHQ3 ^@ Similarity ^@ Belongs to the IUNH family. http://togogenome.org/gene/50390:LOC114339051 ^@ http://purl.uniprot.org/uniprot/A0A6P7GJU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MPP10 family.|||Involved in nucleolar processing of pre-18S ribosomal RNA.|||nucleolus http://togogenome.org/gene/50390:LOC114329903 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 2 family.|||Golgi apparatus membrane http://togogenome.org/gene/50390:LOC114328451 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBW4 ^@ Similarity ^@ Belongs to the MTFP1 family. http://togogenome.org/gene/50390:LOC114325038 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5N9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/50390:LOC114336193 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0I2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114326449 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4K5 ^@ Subcellular Location Annotation ^@ cytosol http://togogenome.org/gene/50390:LOC114327291 ^@ http://purl.uniprot.org/uniprot/A0A6P7F824 ^@ Similarity ^@ Belongs to the complex I 49 kDa subunit family. http://togogenome.org/gene/50390:LOC114325912 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/50390:LOC114339938 ^@ http://purl.uniprot.org/uniprot/A0A6P7GML3 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 2 family.|||Homotetramer.|||Inhibited by L-aspartic acid.|||Plays an important role in the degradation of dermatan and keratan sulfates. http://togogenome.org/gene/50390:LOC114325624 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7V3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114326368 ^@ http://purl.uniprot.org/uniprot/A0A6P7F501 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ENY2 family.|||Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).|||Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.|||nucleoplasm http://togogenome.org/gene/50390:LOC114329758 ^@ http://purl.uniprot.org/uniprot/A0A6P7FG00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Membrane http://togogenome.org/gene/50390:LOC114327176 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7N6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114348462 ^@ http://purl.uniprot.org/uniprot/A0A6P7GZQ1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114331430 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLB4 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/50390:LOC114325393 ^@ http://purl.uniprot.org/uniprot/A0A6P7F302 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruB family. http://togogenome.org/gene/50390:LOC114330875 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJ30|||http://purl.uniprot.org/uniprot/A0A6P7FJF7|||http://purl.uniprot.org/uniprot/A0A6P7FT16 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114331355 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF12 family.|||Nucleus http://togogenome.org/gene/50390:LOC114343227 ^@ http://purl.uniprot.org/uniprot/A0A6P7H1D0 ^@ Similarity ^@ Belongs to the FAM91 family. http://togogenome.org/gene/50390:LOC114335300 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXN1|||http://purl.uniprot.org/uniprot/A0A6P7GA41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.|||Membrane http://togogenome.org/gene/50390:LOC114338616 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7C6|||http://purl.uniprot.org/uniprot/A0A6P7GFV5 ^@ Similarity ^@ Belongs to the eukaryotic mitochondrial porin family. http://togogenome.org/gene/50390:LOC114349409 ^@ http://purl.uniprot.org/uniprot/A0A6P7H0R9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Endosome membrane|||Membrane http://togogenome.org/gene/50390:LOC114324610 ^@ http://purl.uniprot.org/uniprot/A0A6P7F328 ^@ Cofactor|||Similarity ^@ Belongs to the transglutaminase superfamily. Transglutaminase family.|||Binds 1 Ca(2+) ion per subunit. http://togogenome.org/gene/50390:LOC114334235 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ30 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114329511 ^@ http://purl.uniprot.org/uniprot/A0A6P7FN67 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/50390:LOC114327935 ^@ http://purl.uniprot.org/uniprot/A0A6P7FH36 ^@ Similarity ^@ Belongs to the HARBI1 family. http://togogenome.org/gene/50390:LOC114324757 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYR0|||http://purl.uniprot.org/uniprot/A0A6P7F3F4|||http://purl.uniprot.org/uniprot/A0A6P7F4K2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Protein transport. Probably involved in vesicular traffic. http://togogenome.org/gene/50390:LOC114333885 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXX6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114325445 ^@ http://purl.uniprot.org/uniprot/A0A6P7F152|||http://purl.uniprot.org/uniprot/A0A6P7F7B3 ^@ Function|||Similarity ^@ Belongs to the ataxin-10 family.|||Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. http://togogenome.org/gene/50390:LOC114333654 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Nucleus http://togogenome.org/gene/50390:LOC114325680 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1W3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114325845 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/50390:LOC114349349 ^@ http://purl.uniprot.org/uniprot/A0A6P7H1U2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114335270 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXX4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DDOST 48 kDa subunit family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). http://togogenome.org/gene/50390:LOC114328909 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKL1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114324427 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYK6|||http://purl.uniprot.org/uniprot/A0A6P7EZP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114334717 ^@ http://purl.uniprot.org/uniprot/A0A6P7FW34 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. http://togogenome.org/gene/50390:LOC114324223 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXU1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114333631 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSS9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Mitochondrion|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.|||nucleolus|||nucleoplasm http://togogenome.org/gene/50390:LOC114341245 ^@ http://purl.uniprot.org/uniprot/A0A6P7GEB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SVP26 family.|||Membrane http://togogenome.org/gene/50390:LOC114333727 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSS6|||http://purl.uniprot.org/uniprot/A0A6P7FST0|||http://purl.uniprot.org/uniprot/A0A6P7FST6|||http://purl.uniprot.org/uniprot/A0A6P7FSU1|||http://purl.uniprot.org/uniprot/A0A6P7FSU6|||http://purl.uniprot.org/uniprot/A0A6P7FSV1|||http://purl.uniprot.org/uniprot/A0A6P7FSV7|||http://purl.uniprot.org/uniprot/A0A6P7FSW6|||http://purl.uniprot.org/uniprot/A0A6P7FT41|||http://purl.uniprot.org/uniprot/A0A6P7FT45|||http://purl.uniprot.org/uniprot/A0A6P7FT50|||http://purl.uniprot.org/uniprot/A0A6P7FT54|||http://purl.uniprot.org/uniprot/A0A6P7FT58|||http://purl.uniprot.org/uniprot/A0A6P7FT78|||http://purl.uniprot.org/uniprot/A0A6P7FXE1|||http://purl.uniprot.org/uniprot/A0A6P7FXF0|||http://purl.uniprot.org/uniprot/A0A6P7FXF5|||http://purl.uniprot.org/uniprot/A0A6P7FXG0|||http://purl.uniprot.org/uniprot/A0A6P7FXH2|||http://purl.uniprot.org/uniprot/A0A6P7G383|||http://purl.uniprot.org/uniprot/A0A6P7G387|||http://purl.uniprot.org/uniprot/A0A6P7G391|||http://purl.uniprot.org/uniprot/A0A6P7G396|||http://purl.uniprot.org/uniprot/A0A6P7G3A1|||http://purl.uniprot.org/uniprot/A0A6P7G3A5|||http://purl.uniprot.org/uniprot/A0A6P7G3B5|||http://purl.uniprot.org/uniprot/A0A6P7G4L3|||http://purl.uniprot.org/uniprot/A0A6P7G4L8|||http://purl.uniprot.org/uniprot/A0A6P7G4M5|||http://purl.uniprot.org/uniprot/A0A6P7G4N0|||http://purl.uniprot.org/uniprot/A0A6P7G4N9|||http://purl.uniprot.org/uniprot/A0A6P7G4Q0|||http://purl.uniprot.org/uniprot/A0A6P7G4Q4 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/50390:LOC114337108 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2W5|||http://purl.uniprot.org/uniprot/A0A6P7G314|||http://purl.uniprot.org/uniprot/A0A6P7G8V2|||http://purl.uniprot.org/uniprot/A0A6P7G8V5|||http://purl.uniprot.org/uniprot/A0A6P7GED1|||http://purl.uniprot.org/uniprot/A0A6P7GHI8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114328619 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCG0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the protein prenyltransferase subunit beta family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.|||Heterodimer of an alpha and a beta subunit. http://togogenome.org/gene/50390:LOC114327929 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGT5 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/50390:LOC114334291 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6I5 ^@ Function|||Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.|||Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. http://togogenome.org/gene/50390:LOC114332689 ^@ http://purl.uniprot.org/uniprot/A0A6P7FU30 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/50390:LOC114328951 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDJ2|||http://purl.uniprot.org/uniprot/A0A6P7FFR0 ^@ Similarity ^@ Belongs to the lin-52 family. http://togogenome.org/gene/50390:LOC114329274 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEG1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114346824 ^@ http://purl.uniprot.org/uniprot/A0A6P7HC92 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/50390:LOC114338187 ^@ http://purl.uniprot.org/uniprot/A0A6P7G683 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NSE4 family.|||Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.|||Component of the SMC5-SMC6 complex.|||Nucleus http://togogenome.org/gene/50390:LOC114344080 ^@ http://purl.uniprot.org/uniprot/A0A6P7GLD9|||http://purl.uniprot.org/uniprot/A0A6P7GM70 ^@ Similarity ^@ Belongs to the TPR family. http://togogenome.org/gene/50390:LOC114325249 ^@ http://purl.uniprot.org/uniprot/A0A6P7F160 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lin-7 family.|||Cell junction|||Cell membrane|||Membrane|||Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. http://togogenome.org/gene/50390:LOC114331432 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLC6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114339537 ^@ http://purl.uniprot.org/uniprot/A0A6P7GL91 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114333360 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRN7|||http://purl.uniprot.org/uniprot/A0A6P7G344 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114336386 ^@ http://purl.uniprot.org/uniprot/A0A6P7G114 ^@ Similarity ^@ Belongs to the peptidase M67A family. BRCC36 subfamily. http://togogenome.org/gene/50390:LOC114332260 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SWEET sugar transporter family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/50390:LOC114331303 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/50390:LOC114331368 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RuvB family.|||Nucleus|||Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. http://togogenome.org/gene/50390:LOC114326217 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0G7|||http://purl.uniprot.org/uniprot/A0A6P7F3Q3|||http://purl.uniprot.org/uniprot/A0A6P7FA12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114342300 ^@ http://purl.uniprot.org/uniprot/A0A6P7GYP8 ^@ Similarity ^@ Belongs to the CDI family. http://togogenome.org/gene/50390:LOC114334821 ^@ http://purl.uniprot.org/uniprot/A0A6P7G848 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114337211 ^@ http://purl.uniprot.org/uniprot/A0A6P7G388|||http://purl.uniprot.org/uniprot/A0A6P7G3E6|||http://purl.uniprot.org/uniprot/A0A6P7G977|||http://purl.uniprot.org/uniprot/A0A6P7G9A9|||http://purl.uniprot.org/uniprot/A0A6P7GEP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP-25 family.|||synaptosome http://togogenome.org/gene/50390:LOC114324850 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3V2 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/50390:LOC114336133 ^@ http://purl.uniprot.org/uniprot/A0A6P7G048|||http://purl.uniprot.org/uniprot/A0A6P7G0C5|||http://purl.uniprot.org/uniprot/A0A6P7GBP9 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/50390:LOC114334633 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7M5 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/50390:LOC114349355 ^@ http://purl.uniprot.org/uniprot/A0A6P7HD09 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/50390:LOC114325338 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0T7|||http://purl.uniprot.org/uniprot/A0A6P7F1I6|||http://purl.uniprot.org/uniprot/A0A6P7F2U1|||http://purl.uniprot.org/uniprot/A0A6P7F5Z9|||http://purl.uniprot.org/uniprot/A0A6P7F6Y4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FMO family.|||Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.|||Endoplasmic reticulum membrane|||Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114325045 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5P4 ^@ Function|||Similarity ^@ Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).|||Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.|||Essential arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins SmD1 and SmD3. http://togogenome.org/gene/50390:LOC114324443 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYM7|||http://purl.uniprot.org/uniprot/A0A6P7EZS3|||http://purl.uniprot.org/uniprot/A0A6P7F2H4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ninjurin family.|||Membrane http://togogenome.org/gene/50390:LOC114327468 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114329724 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIB7|||http://purl.uniprot.org/uniprot/A0A6P7FNZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FCHO family.|||clathrin-coated pit http://togogenome.org/gene/50390:LOC114330888 ^@ http://purl.uniprot.org/uniprot/A0A6P7FT31 ^@ Similarity ^@ Belongs to the SINA (Seven in absentia) family. http://togogenome.org/gene/50390:LOC114331299 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKF0|||http://purl.uniprot.org/uniprot/A0A6P7FKS9|||http://purl.uniprot.org/uniprot/A0A6P7FV63 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. http://togogenome.org/gene/50390:LOC114332956 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQF4 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/50390:LOC114349464 ^@ http://purl.uniprot.org/uniprot/A0A6P7HJ70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0220 family.|||Membrane http://togogenome.org/gene/50390:LOC114326337 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4V1|||http://purl.uniprot.org/uniprot/A0A6P7F6K7 ^@ Similarity ^@ Belongs to the AAA ATPase family. PCH2 subfamily. http://togogenome.org/gene/50390:LOC114328897 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCI2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Belongs to the scoloptoxin-05 family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/50390:LOC114325292 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6P7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/50390:LOC114327916 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9C3|||http://purl.uniprot.org/uniprot/A0A6P7FA64 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the clathrin light chain family.|||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.|||Cytoplasmic vesicle membrane|||coated pit http://togogenome.org/gene/50390:LOC114336778 ^@ http://purl.uniprot.org/uniprot/A0A6P7G239 ^@ Similarity|||Subunit ^@ Belongs to the peptidase C78 family. ZUFSP subfamily.|||Interacts with RPA1 and RPA2. http://togogenome.org/gene/50390:LOC114332106 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Membrane http://togogenome.org/gene/50390:LOC114334629 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVI7|||http://purl.uniprot.org/uniprot/A0A6P7G6M3 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114332814 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPZ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114334463 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5W2|||http://purl.uniprot.org/uniprot/A0A6P7G712 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/50390:LOC114324611 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM231 family.|||Membrane|||Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.|||cilium membrane http://togogenome.org/gene/50390:LOC114331954 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL53 family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114326452 ^@ http://purl.uniprot.org/uniprot/A0A6P7F711 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/50390:LOC114330029 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQ47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM132 family.|||Membrane http://togogenome.org/gene/50390:LOC114339820 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP SmB/SmN family.|||Nucleus http://togogenome.org/gene/50390:LOC114329650 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNV2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.|||Belongs to the carbohydrate kinase PfkB family.|||Binds 3 Mg(2+) ions per subunit.|||Monomer.|||Nucleus http://togogenome.org/gene/50390:LOC114333875 ^@ http://purl.uniprot.org/uniprot/A0A6P7G570 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114326776 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6A0 ^@ Similarity ^@ Belongs to the NADP-dependent oxidoreductase L4BD family. http://togogenome.org/gene/50390:LOC114334606 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6I9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Golgi pH regulator (TC 1.A.38) family.|||Membrane http://togogenome.org/gene/50390:LOC114327551 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB50 ^@ Similarity ^@ Belongs to the FAM114 family. http://togogenome.org/gene/50390:LOC114333874 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXW6|||http://purl.uniprot.org/uniprot/A0A6P7G580 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM120 family.|||Membrane http://togogenome.org/gene/50390:LOC114343207 ^@ http://purl.uniprot.org/uniprot/A0A6P7GJJ2 ^@ Similarity ^@ Belongs to the apyrase family. http://togogenome.org/gene/50390:LOC114341351 ^@ http://purl.uniprot.org/uniprot/A0A6P7GEE1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114341247 ^@ http://purl.uniprot.org/uniprot/A0A6P7GRG0 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/50390:LOC114326246 ^@ http://purl.uniprot.org/uniprot/A0A6P7F697 ^@ Domain|||Function|||PTM|||Subcellular Location Annotation ^@ E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.|||The WWE domain mediates non-covalent poly(ADP-ribose)-binding.|||Ubiquitinated; autoubiquitinated.|||cytosol http://togogenome.org/gene/50390:LOC114326498 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4T1|||http://purl.uniprot.org/uniprot/A0A6P7FB63 ^@ Similarity ^@ Belongs to the acyl-CoA oxidase family. http://togogenome.org/gene/50390:LOC114324462 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYP7|||http://purl.uniprot.org/uniprot/A0A6P7F2K5 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/50390:LOC114325992 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2U5 ^@ Similarity ^@ Belongs to the major royal jelly protein family. http://togogenome.org/gene/50390:LOC114341438 ^@ http://purl.uniprot.org/uniprot/A0A6P7GEP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FIP1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114342483 ^@ http://purl.uniprot.org/uniprot/A0A6P7GH21|||http://purl.uniprot.org/uniprot/A0A6P7GSQ6|||http://purl.uniprot.org/uniprot/A0A6P7GUM1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/50390:LOC114335453 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3A4|||http://purl.uniprot.org/uniprot/A0A6P7GAQ8 ^@ Similarity ^@ Belongs to the peptidase S8 family. Furin subfamily. http://togogenome.org/gene/50390:LOC114328871 ^@ http://purl.uniprot.org/uniprot/A0A2I6PIY3 ^@ Similarity ^@ Belongs to the argonaute family. http://togogenome.org/gene/50390:LOC114334085 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUA9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114337261 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3B6|||http://purl.uniprot.org/uniprot/A0A6P7GES6 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/50390:LOC114328431 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJ87 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/50390:LOC114334656 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DUOXA family.|||Membrane http://togogenome.org/gene/50390:LOC114329113 ^@ http://purl.uniprot.org/uniprot/A0A6P7FG87|||http://purl.uniprot.org/uniprot/A0A6P7FLF3|||http://purl.uniprot.org/uniprot/A0A6P7FLS9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/50390:LOC114331100 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M13 family.|||Cell membrane http://togogenome.org/gene/50390:LOC114335158 ^@ http://purl.uniprot.org/uniprot/A0A6P7FX57 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/50390:LOC114333215 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1F1 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/50390:LOC114324941 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4B1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114343248 ^@ http://purl.uniprot.org/uniprot/A0A290WID3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.|||Vacuole membrane http://togogenome.org/gene/50390:LOC114327178 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDQ0 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114330624 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLM3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation. http://togogenome.org/gene/50390:LOC114329555 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFC9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114332532 ^@ http://purl.uniprot.org/uniprot/A0A6P7FP67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL51 family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114324152 ^@ http://purl.uniprot.org/uniprot/A0A6P7EX40|||http://purl.uniprot.org/uniprot/A0A6P7F182|||http://purl.uniprot.org/uniprot/A0A6P7F2E9 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/50390:LOC114327399 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7R7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/50390:LOC114325457 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1Y9 ^@ Similarity ^@ Belongs to the peptidase S28 family. http://togogenome.org/gene/50390:LOC114328525 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP11 family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114329869 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFV2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/50390:LOC114331037 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJZ3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/50390:LOC114324374 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114334081 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4J4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATOS family.|||Nucleus http://togogenome.org/gene/50390:LOC114329310 ^@ http://purl.uniprot.org/uniprot/A0A6P7FM70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM170 family.|||Membrane http://togogenome.org/gene/50390:LOC114325112 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4Y1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Late endosome membrane|||Membrane http://togogenome.org/gene/50390:LOC114326775 ^@ http://purl.uniprot.org/uniprot/A0A6P7F857|||http://purl.uniprot.org/uniprot/A0A6P7FC10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad21 family.|||Nucleus http://togogenome.org/gene/50390:LOC114336314 ^@ http://purl.uniprot.org/uniprot/A0A6P7H5R5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114336403 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6C6 ^@ Function|||Similarity ^@ Belongs to the MGR2 family.|||Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.|||Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation. http://togogenome.org/gene/50390:LOC114331161 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNS8|||http://purl.uniprot.org/uniprot/A0A6P7FU01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.|||Belongs to the sulfotransferase 6 family.|||Membrane http://togogenome.org/gene/50390:LOC114326835 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5T0|||http://purl.uniprot.org/uniprot/A0A6P7FCA9|||http://purl.uniprot.org/uniprot/A0A6P7FCG2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114331337 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKH9 ^@ Similarity ^@ Belongs to the lin-9 family. http://togogenome.org/gene/50390:LOC114326855 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8J0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyl hydrolase 27 family.|||Homodimer.|||Lysosome http://togogenome.org/gene/50390:LOC114330951 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTC0 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/50390:LOC114331074 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUD1 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/50390:LOC114331876 ^@ http://purl.uniprot.org/uniprot/A0A6P7FM91|||http://purl.uniprot.org/uniprot/A0A6P7FWV5|||http://purl.uniprot.org/uniprot/A0A6P7FXS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MLF family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114342350 ^@ http://purl.uniprot.org/uniprot/A0A6P7GSD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyadenylate-binding protein type-1 family.|||Binds the poly(A) tail of mRNA.|||Cytoplasm http://togogenome.org/gene/50390:LOC114338396 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6U8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114326524 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4Z5 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/50390:LOC114327919 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9C8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.|||Belongs to the arsA ATPase family.|||Cytoplasm|||Endoplasmic reticulum|||Homodimer. http://togogenome.org/gene/50390:LOC114329818 ^@ http://purl.uniprot.org/uniprot/A0A6P7FG78|||http://purl.uniprot.org/uniprot/A0A6P7FIQ7|||http://purl.uniprot.org/uniprot/A0A6P7FPE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114324215 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS25 family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114326427 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4H4|||http://purl.uniprot.org/uniprot/A0A6P7FAH2|||http://purl.uniprot.org/uniprot/A0A6P7FAH6 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/50390:LOC114331282 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKD4|||http://purl.uniprot.org/uniprot/A0A6P7FP89|||http://purl.uniprot.org/uniprot/A0A6P7FUG8|||http://purl.uniprot.org/uniprot/A0A6P7FV42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114342154 ^@ http://purl.uniprot.org/uniprot/A0A6P7GRR0 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/50390:LOC114329379 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMJ5 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/50390:LOC114331208 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRIM/RBCC family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114327375 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8C4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL38 family. http://togogenome.org/gene/50390:LOC114334819 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0Z6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114327699 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9G2|||http://purl.uniprot.org/uniprot/A0A6P7FG19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrimidine 5'-nucleotidase family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114333481 ^@ http://purl.uniprot.org/uniprot/A0A6P7G295 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).|||Nucleus http://togogenome.org/gene/50390:LOC114331336 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV99 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/50390:LOC114324509 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2Q0 ^@ Function|||Similarity ^@ Belongs to the tubulin family.|||Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. http://togogenome.org/gene/50390:LOC114327391 ^@ http://purl.uniprot.org/uniprot/A0A6P7FF82 ^@ Similarity ^@ Belongs to the HARBI1 family. http://togogenome.org/gene/50390:LOC114326345 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4W1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom20 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/50390:LOC114328004 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHD4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/50390:LOC114326476 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial ribosomal protein bL35 family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114328578 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114328948 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCN1|||http://purl.uniprot.org/uniprot/A0A6P7FDI2|||http://purl.uniprot.org/uniprot/A0A6P7FFQ1|||http://purl.uniprot.org/uniprot/A0A6P7FKR5|||http://purl.uniprot.org/uniprot/A0A6P7FL91 ^@ Similarity ^@ Belongs to the WD repeat EMAP family. http://togogenome.org/gene/50390:LOC114326968 ^@ http://purl.uniprot.org/uniprot/A0A6P7F916 ^@ Similarity ^@ Belongs to the RNase T2 family. http://togogenome.org/gene/50390:LOC114338420 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6W2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UQCRQ/QCR8 family.|||Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114335714 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ07 ^@ Similarity ^@ Belongs to the Toll-like receptor family. http://togogenome.org/gene/50390:LOC114326690 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5Z5 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/50390:LOC114328261 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 26 family.|||Nucleus http://togogenome.org/gene/50390:LOC114330125 ^@ http://purl.uniprot.org/uniprot/A0A6P7FH70 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/50390:LOC114345104 ^@ http://purl.uniprot.org/uniprot/A0A6P7H207 ^@ Function|||Similarity|||Subunit ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.|||Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site. http://togogenome.org/gene/50390:LOC114329891 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQ37 ^@ Similarity ^@ Belongs to the ubiquitin family. http://togogenome.org/gene/50390:LOC114327058 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C26 family.|||extracellular space http://togogenome.org/gene/50390:LOC114347270 ^@ http://purl.uniprot.org/uniprot/A0A6P7HDF3 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114327513 ^@ http://purl.uniprot.org/uniprot/A0A6P7F836 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Nucleus membrane|||Rough endoplasmic reticulum membrane http://togogenome.org/gene/50390:LOC114329522 ^@ http://purl.uniprot.org/uniprot/A0A6P7FN65 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114328482 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB66 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/50390:LOC114329340 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMC4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. http://togogenome.org/gene/50390:LOC114336237 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0F2|||http://purl.uniprot.org/uniprot/A0A6P7G5R9|||http://purl.uniprot.org/uniprot/A0A6P7GBY9|||http://purl.uniprot.org/uniprot/A0A6P7GDZ9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family.|||Binds 2 Zn(2+) ions per subunit.|||Cytoplasm http://togogenome.org/gene/50390:LOC114330979 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJS4 ^@ Similarity ^@ Belongs to the NPC2 family. http://togogenome.org/gene/50390:LOC114339958 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAV3|||http://purl.uniprot.org/uniprot/A0A6P7GAV6|||http://purl.uniprot.org/uniprot/A0A6P7GKG1|||http://purl.uniprot.org/uniprot/A0A6P7GRL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NRF1/Ewg family.|||Nucleus http://togogenome.org/gene/50390:LOC114347120 ^@ http://purl.uniprot.org/uniprot/A0A6P7GVX5 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114329718 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114325846 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2D1 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/50390:LOC114334950 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/50390:LOC114335796 ^@ http://purl.uniprot.org/uniprot/A0A6P7GC54 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/50390:LOC114324701 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZK4 ^@ Subcellular Location Annotation ^@ centrosome|||perinuclear region http://togogenome.org/gene/50390:LOC114342864 ^@ http://purl.uniprot.org/uniprot/A0A6P7GIA6 ^@ Similarity ^@ Belongs to the TAF9 family. CENP-S/MHF1 subfamily. http://togogenome.org/gene/50390:LOC114338552 ^@ http://purl.uniprot.org/uniprot/A0A6P7G770 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/50390:LOC114334783 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVY0 ^@ Similarity ^@ Belongs to the GLI C2H2-type zinc-finger protein family. http://togogenome.org/gene/50390:LOC114331205 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKI1 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/50390:LOC114337485 ^@ http://purl.uniprot.org/uniprot/A0A6P7GFF5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/50390:LOC114335787 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4D9 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/50390:LOC114343546 ^@ http://purl.uniprot.org/uniprot/A0A6P7H286 ^@ Function|||Similarity ^@ Belongs to the TSR2 family.|||May be involved in 20S pre-rRNA processing. http://togogenome.org/gene/50390:LOC114325801 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8E2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/50390:LOC114333205 ^@ http://purl.uniprot.org/uniprot/A0A6P7FR88|||http://purl.uniprot.org/uniprot/A0A6P7G1E6|||http://purl.uniprot.org/uniprot/A0A6P7G1G0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114342404 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGX4|||http://purl.uniprot.org/uniprot/A0A6P7GUE8|||http://purl.uniprot.org/uniprot/A0A6P7GUG2|||http://purl.uniprot.org/uniprot/A0A6P7GZ03 ^@ Similarity ^@ Belongs to the PDGF/VEGF growth factor family. http://togogenome.org/gene/50390:LOC114324409 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3F6 ^@ Similarity ^@ Belongs to the ACTMAP family. http://togogenome.org/gene/50390:LOC114325949 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3F5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNF10 family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114325462 ^@ http://purl.uniprot.org/uniprot/A0A6P7F175 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/50390:LOC114326753 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBY3 ^@ Function ^@ Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA. http://togogenome.org/gene/50390:LOC114327335 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7F8|||http://purl.uniprot.org/uniprot/A0A6P7FEE1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114347933 ^@ http://purl.uniprot.org/uniprot/A0A6P7GY77 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/50390:LOC114328846 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKB3|||http://purl.uniprot.org/uniprot/A0A6P7FKZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 3 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/50390:LOC114333155 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2G0 ^@ Similarity ^@ Belongs to the homogentisate dioxygenase family. http://togogenome.org/gene/50390:LOC114330224 ^@ http://purl.uniprot.org/uniprot/A0A6P7FH11 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.|||Cell membrane|||Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. http://togogenome.org/gene/50390:LOC114329510 ^@ http://purl.uniprot.org/uniprot/A0A6P7FF86 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/50390:LOC114324472 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYR6 ^@ Similarity ^@ Belongs to the proteasome subunit S3 family. http://togogenome.org/gene/50390:LOC114330041 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQB4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114330245 ^@ http://purl.uniprot.org/uniprot/A0A6P7FH27 ^@ Similarity ^@ Belongs to the peptidase S1 family. CLIP subfamily. http://togogenome.org/gene/50390:LOC114325617 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2G7 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/50390:LOC114347809 ^@ http://purl.uniprot.org/uniprot/A0A6P7H9F6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114326198 ^@ http://purl.uniprot.org/uniprot/A0A6P7F605 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicastrin family.|||Membrane http://togogenome.org/gene/50390:LOC114326552 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBC0 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/50390:LOC114335851 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAS5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/50390:LOC114340553 ^@ http://purl.uniprot.org/uniprot/A0A6P7GTJ4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS1 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).|||Cytoplasm http://togogenome.org/gene/50390:LOC114338332 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6P0 ^@ Similarity ^@ Belongs to the G protein gamma family. http://togogenome.org/gene/50390:LOC114335594 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3P5|||http://purl.uniprot.org/uniprot/A0A6P7GB50 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/50390:LOC114327458 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7X4|||http://purl.uniprot.org/uniprot/A0A6P7F8M9|||http://purl.uniprot.org/uniprot/A0A6P7FAR2|||http://purl.uniprot.org/uniprot/A0A6P7FEV9|||http://purl.uniprot.org/uniprot/A0A6P7FF48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TDE1 family.|||Membrane http://togogenome.org/gene/50390:LOC114329377 ^@ http://purl.uniprot.org/uniprot/A0A6P7FET4 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/50390:LOC114332110 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMW2|||http://purl.uniprot.org/uniprot/A0A6P7FNB7 ^@ Similarity ^@ Belongs to the sulfiredoxin family. http://togogenome.org/gene/50390:LOC114327569 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFK2 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/50390:LOC114341660 ^@ http://purl.uniprot.org/uniprot/A0A6P7GF91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 11 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/50390:LOC114332273 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FBXO45/Fsn family.|||Synapse http://togogenome.org/gene/50390:LOC114332736 ^@ http://purl.uniprot.org/uniprot/A0A6P7G132 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM59 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/50390:LOC114342825 ^@ http://purl.uniprot.org/uniprot/A0A6P7GHU7|||http://purl.uniprot.org/uniprot/A0A6P7H075 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Mitochondrion http://togogenome.org/gene/50390:LOC114337347 ^@ http://purl.uniprot.org/uniprot/A0A6P7GIE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Membrane http://togogenome.org/gene/50390:LOC114332701 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPU2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114327917 ^@ http://purl.uniprot.org/uniprot/A0A6P7FC90 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/50390:LOC114349340 ^@ http://purl.uniprot.org/uniprot/A0A6P7HA02 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the protein prenyltransferase subunit beta family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX. http://togogenome.org/gene/50390:LOC114325672 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1U6|||http://purl.uniprot.org/uniprot/A0A6P7F414 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114332663 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQ05|||http://purl.uniprot.org/uniprot/A0A6P7FU09 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114331986 ^@ http://purl.uniprot.org/uniprot/A0A6P7FY45 ^@ Similarity ^@ Belongs to the TENT family. http://togogenome.org/gene/50390:LOC114324346 ^@ http://purl.uniprot.org/uniprot/A0A6P7F366 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/50390:LOC114331204 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUS3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphatidyl serine synthase family.|||Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114332833 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUD2 ^@ Similarity ^@ Belongs to the eIF-2-alpha family. http://togogenome.org/gene/50390:LOC114326207 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4D7|||http://purl.uniprot.org/uniprot/A0A6P7F9Y5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114335492 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9M8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/50390:LOC114327845 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9Y3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/50390:LOC114335226 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXE4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/50390:LOC114337044 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8J3 ^@ Similarity ^@ Belongs to the tubulin family. http://togogenome.org/gene/50390:LOC114327272 ^@ http://purl.uniprot.org/uniprot/A0A6P7FA37|||http://purl.uniprot.org/uniprot/A0A6P7FE48 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/50390:LOC114330132 ^@ http://purl.uniprot.org/uniprot/A0A6P7FH44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mago nashi family.|||Nucleus http://togogenome.org/gene/50390:LOC114336467 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1A0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SNF8 family.|||Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.|||Component of the endosomal sorting complex required for transport II (ESCRT-II). http://togogenome.org/gene/50390:LOC114327160 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6S6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TBCC family.|||Cytoplasm|||Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state. http://togogenome.org/gene/50390:LOC114332066 ^@ http://purl.uniprot.org/uniprot/A0A6P7FN66 ^@ Similarity ^@ Belongs to the Ntn-hydrolase family. http://togogenome.org/gene/50390:LOC114326876 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCK0 ^@ Similarity ^@ Belongs to the carnosine N-methyltransferase family. http://togogenome.org/gene/50390:LOC114325900 ^@ http://purl.uniprot.org/uniprot/A0A6P7F399|||http://purl.uniprot.org/uniprot/A0A6P7F4P5|||http://purl.uniprot.org/uniprot/A0A6P7F840 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. http://togogenome.org/gene/50390:LOC114340704 ^@ http://purl.uniprot.org/uniprot/A0A6P7GTW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPEG family.|||Membrane http://togogenome.org/gene/50390:LOC114349497 ^@ http://purl.uniprot.org/uniprot/A0A6P7H121|||http://purl.uniprot.org/uniprot/A0A6P7HAI3|||http://purl.uniprot.org/uniprot/A0A6P7HDK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114336425 ^@ http://purl.uniprot.org/uniprot/A0A6P7GET5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114340457 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 47 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/50390:LOC114332919 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQB1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/50390:LOC114327223 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7T2|||http://purl.uniprot.org/uniprot/A0A6P7FDY4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ITPK1 family.|||Binds 2 magnesium ions per subunit.|||Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.|||Monomer. http://togogenome.org/gene/50390:LOC114328621 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEQ9 ^@ Similarity ^@ Belongs to the KXD1 family. http://togogenome.org/gene/50390:LOC114329649 ^@ http://purl.uniprot.org/uniprot/A0A6P7FF27 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.|||Belongs to the carbohydrate kinase PfkB family.|||Binds 3 Mg(2+) ions per subunit.|||Monomer.|||Nucleus http://togogenome.org/gene/50390:LOC114334307 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZE6 ^@ Similarity ^@ Belongs to the complex I 30 kDa subunit family. http://togogenome.org/gene/50390:LOC114335847 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZC4 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/50390:LOC114331136 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/50390:LOC114329002 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114327208 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDW4 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/50390:LOC114335313 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-gamma family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/50390:LOC114326773 ^@ http://purl.uniprot.org/uniprot/A0A6P7FC68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ACDP family.|||Membrane http://togogenome.org/gene/50390:LOC114332605 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZG1 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/50390:LOC114325772 ^@ http://purl.uniprot.org/uniprot/A0A6P7F250 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114331668 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLJ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.|||Nucleus http://togogenome.org/gene/50390:LOC114335810 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AXUD1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114335315 ^@ http://purl.uniprot.org/uniprot/A0A6P7G925 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/50390:LOC114325149 ^@ http://purl.uniprot.org/uniprot/A0A6P7F640 ^@ Similarity ^@ Belongs to the centrin family. http://togogenome.org/gene/50390:LOC114336064 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5A2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DDB1 family.|||Cytoplasm|||Nucleus|||Plays a role in DNA repair. May be a component of an E3 ubiquitin-protein ligase which promotes histone ubiquitination in response to UV irradiation. Histone ubiquitination may be important for subsequent DNA repair. http://togogenome.org/gene/50390:LOC114327550 ^@ http://purl.uniprot.org/uniprot/A0A6P7F904 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Apical cell membrane|||Belongs to the WWC family. KIBRA subfamily.|||Forms a complex with Mer and Ex. Interacts (via domain WW 1) with Ex (via RXPPXY motif). Interacts with Mer, Sav, Hpo and Wts.|||Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. Kibra acts synergistically along with Ex and Mer to regulate the Hippo signaling pathway. http://togogenome.org/gene/50390:LOC114332823 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUC3 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/50390:LOC114328184 ^@ http://purl.uniprot.org/uniprot/A0A6P7FD85 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/50390:LOC114333429 ^@ http://purl.uniprot.org/uniprot/A0A6P7FS31 ^@ Similarity ^@ Belongs to the pseudouridine synthase Pus10 family. http://togogenome.org/gene/50390:LOC114332504 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ45|||http://purl.uniprot.org/uniprot/A0A6P7G096 ^@ Similarity ^@ Belongs to the RRM IMP/VICKZ family. http://togogenome.org/gene/50390:LOC114331422 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVS2 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/50390:LOC114347258 ^@ http://purl.uniprot.org/uniprot/A0A6P7GVL8 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114333158 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2G5 ^@ Similarity ^@ Belongs to the GHMP kinase family. GalK subfamily. http://togogenome.org/gene/50390:LOC114346158 ^@ http://purl.uniprot.org/uniprot/A0A6P7H5N9 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/50390:LOC114334526 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV89|||http://purl.uniprot.org/uniprot/A0A6P7G012|||http://purl.uniprot.org/uniprot/A0A6P7G692 ^@ Similarity ^@ Belongs to the UPL family. TOM1/PTR1 subfamily. http://togogenome.org/gene/50390:LOC114325882 ^@ http://purl.uniprot.org/uniprot/A0A6P7F811 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114342777 ^@ http://purl.uniprot.org/uniprot/A0A6P7GHQ0 ^@ Similarity ^@ Belongs to the SERF family. http://togogenome.org/gene/50390:LOC114333422 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3E8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS1/PSF1 family.|||Component of the GINS complex.|||Nucleus|||Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. http://togogenome.org/gene/50390:LOC114326518 ^@ http://purl.uniprot.org/uniprot/A0A6P7F788 ^@ Similarity ^@ Belongs to the NOP10 family. http://togogenome.org/gene/50390:LOC114330260 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114325293 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1B8|||http://purl.uniprot.org/uniprot/A0A6P7F2K8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PUR DNA-binding protein family.|||Nucleus http://togogenome.org/gene/50390:LOC114330450 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRV2 ^@ Similarity ^@ Belongs to the Toll-like receptor family. http://togogenome.org/gene/50390:LOC114349445 ^@ http://purl.uniprot.org/uniprot/A0A6P7H283 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/50390:LOC114331431 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPW7 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/50390:LOC114331338 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVA4 ^@ Subcellular Location Annotation ^@ nuclear pore complex http://togogenome.org/gene/50390:LOC114334359 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV17 ^@ Similarity ^@ Belongs to the glycosyltransferase 32 family. http://togogenome.org/gene/50390:LOC114339212 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8Z0|||http://purl.uniprot.org/uniprot/A0A6P7G954|||http://purl.uniprot.org/uniprot/A0A6P7G9H7|||http://purl.uniprot.org/uniprot/A0A6P7GA26|||http://purl.uniprot.org/uniprot/A0A6P7GL38 ^@ Similarity ^@ Belongs to the formin homology family. Diaphanous subfamily. http://togogenome.org/gene/50390:LOC114337260 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9C8|||http://purl.uniprot.org/uniprot/A0A6P7GI55 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/50390:LOC114349424 ^@ http://purl.uniprot.org/uniprot/A0A6P7HAA0 ^@ Similarity ^@ Belongs to the GLI C2H2-type zinc-finger protein family. http://togogenome.org/gene/50390:LOC114331278 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PER33/POM33 family.|||Membrane http://togogenome.org/gene/50390:LOC114340604 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. GCN5 subfamily.|||centrosome http://togogenome.org/gene/50390:LOC114337484 ^@ http://purl.uniprot.org/uniprot/A0A6P7G466 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. http://togogenome.org/gene/50390:LOC114326956 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8X0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 47 family. http://togogenome.org/gene/50390:LOC114334516 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV81 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/50390:LOC114325113 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5Y8 ^@ Similarity ^@ Belongs to the PDCD4 family. http://togogenome.org/gene/50390:LOC114327612 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8F7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/50390:LOC114339105 ^@ http://purl.uniprot.org/uniprot/A0A6P7GI41 ^@ Similarity|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Monomer. http://togogenome.org/gene/50390:LOC114331048 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTN6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.|||Cell membrane|||Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. http://togogenome.org/gene/50390:LOC114329988 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQ56 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/50390:LOC114332216 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ25 ^@ Function ^@ Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA. http://togogenome.org/gene/50390:LOC114339948 ^@ http://purl.uniprot.org/uniprot/A0A6P7GKF7|||http://purl.uniprot.org/uniprot/A0A6P7GRK7 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 2 family.|||Homotetramer.|||Inhibited by L-aspartic acid.|||Plays an important role in the degradation of dermatan and keratan sulfates. http://togogenome.org/gene/50390:LOC114327129 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDH0 ^@ Similarity ^@ Belongs to the peptidase S1 family. CLIP subfamily. http://togogenome.org/gene/50390:LOC114330333 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHT4 ^@ Similarity ^@ Belongs to the SMP-30/CGR1 family. http://togogenome.org/gene/50390:LOC114329469 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMY9|||http://purl.uniprot.org/uniprot/A0A6P7FN24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP-dependent AMP-binding enzyme family.|||Peroxisome http://togogenome.org/gene/50390:LOC114336065 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZY2|||http://purl.uniprot.org/uniprot/A0A6P7GBG5|||http://purl.uniprot.org/uniprot/A0A6P7GDC5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation.|||Belongs to the AAA ATPase family. Spastin subfamily.|||Homohexamer. The homohexamer is stabilized by ATP-binding. The homohexamer may adopt a ring conformation through which microtubules pass prior to being severed. Interacts with microtubules.|||Membrane|||centrosome|||cytoskeleton http://togogenome.org/gene/50390:LOC114335112 ^@ http://purl.uniprot.org/uniprot/A0A6P7G246 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/50390:LOC114337173 ^@ http://purl.uniprot.org/uniprot/A0A6P7G333|||http://purl.uniprot.org/uniprot/A0A6P7GEJ6 ^@ Similarity ^@ Belongs to the RPAP1 family. http://togogenome.org/gene/50390:LOC114335020 ^@ http://purl.uniprot.org/uniprot/A0A6P7G913 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/50390:LOC114324914 ^@ http://purl.uniprot.org/uniprot/A0A6P7F191 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UQCRQ/QCR8 family.|||Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114347380 ^@ http://purl.uniprot.org/uniprot/A0A6P7GWP6|||http://purl.uniprot.org/uniprot/A0A6P7GWQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C19 family.|||Belongs to the peptidase C19 family. USP20/USP33 subfamily.|||centrosome|||perinuclear region http://togogenome.org/gene/50390:LOC114332057 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYE1 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 38 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/50390:LOC114334530 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV93 ^@ Similarity ^@ Belongs to the CBP3 family. http://togogenome.org/gene/50390:LOC114349359 ^@ http://purl.uniprot.org/uniprot/A0A6P7H1V6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/50390:LOC114325832 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7W2|||http://purl.uniprot.org/uniprot/A0A6P7F8I1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PGAP3 family.|||Golgi apparatus membrane|||Involved in the lipid remodeling steps of GPI-anchor maturation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114342231 ^@ http://purl.uniprot.org/uniprot/A0A6P7GTX8 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114345361 ^@ http://purl.uniprot.org/uniprot/A0A6P7H7S3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/50390:LOC114340775 ^@ http://purl.uniprot.org/uniprot/A0A6P7GD58|||http://purl.uniprot.org/uniprot/A0A6P7GMY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/50390:LOC114330105 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGQ6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114329726 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFV6|||http://purl.uniprot.org/uniprot/A0A6P7FIC2 ^@ Function|||Similarity ^@ Belongs to the hyi family.|||Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde). http://togogenome.org/gene/50390:LOC114338247 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6G5 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114340256 ^@ http://purl.uniprot.org/uniprot/A0A6P7GBP1|||http://purl.uniprot.org/uniprot/A0A6P7GBX0|||http://purl.uniprot.org/uniprot/A0A6P7GNL7|||http://purl.uniprot.org/uniprot/A0A6P7GSJ2 ^@ Similarity ^@ Belongs to the SOGA family. http://togogenome.org/gene/50390:LOC114330326 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHA4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPC7 RNA polymerase subunit family.|||Component of the RNA polymerase III (Pol III) complex.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.|||Nucleus http://togogenome.org/gene/50390:LOC114329922 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJ28 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GcvP family.|||Mitochondrion|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/50390:LOC114325996 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2T0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114324910 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZB1|||http://purl.uniprot.org/uniprot/A0A6P7F452|||http://purl.uniprot.org/uniprot/A0A6P7F592 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the THOC2 family.|||Component of the THO complex, which is composed of THOC1, THOC2, THOC3, THOC5, THOC6 and THOC7; together with at least ALYREF/THOC4, DDX39B, SARNP/CIP29 and CHTOP, THO forms the transcription/export (TREX) complex which seems to have a dynamic structure involving ATP-dependent remodeling. Interacts with THOC1, POLDIP3 and ZC3H11A.|||Nucleus http://togogenome.org/gene/50390:LOC114327117 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7E7 ^@ Subcellular Location Annotation ^@ Synapse|||axon|||dendritic spine http://togogenome.org/gene/50390:LOC114342301 ^@ http://purl.uniprot.org/uniprot/A0A6P7GU39 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily. http://togogenome.org/gene/50390:LOC114330085 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGM4|||http://purl.uniprot.org/uniprot/A0A6P7FQB8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114332620 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells. In non-neuronal cells wls directs wg secretion. The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26). In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exosome-like vesicles. Postsynaptic wls is required for the trafficking of fz2 through the fz2-interacting protein Grip.|||Belongs to the wntless family.|||Endoplasmic reticulum membrane|||Endosome membrane|||Golgi apparatus membrane|||Interacts with wg; in the Golgi. Interacts with Vps35, a component of the retromer complex; wls stability is regulated by Vps35.|||Membrane|||Postsynaptic cell membrane|||Presynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/50390:LOC114326751 ^@ http://purl.uniprot.org/uniprot/A0A6P7F830 ^@ Similarity ^@ Belongs to the ANP32 family. http://togogenome.org/gene/50390:LOC114324240 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXE0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the insulin family.|||Heterodimer of a B chain and an A chain linked by two disulfide bonds.|||Secreted http://togogenome.org/gene/50390:LOC114329755 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFF6 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/50390:LOC114330340 ^@ http://purl.uniprot.org/uniprot/A0A6P7FR62 ^@ Similarity ^@ Belongs to the SMP-30/CGR1 family. http://togogenome.org/gene/50390:LOC114333166 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VTI1 family.|||Membrane http://togogenome.org/gene/50390:LOC114325270 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6L3 ^@ Subunit ^@ Bindings to phosphatidylinositol 3-kinase and SHP2. http://togogenome.org/gene/50390:LOC114338867 ^@ http://purl.uniprot.org/uniprot/A0A6P7G839|||http://purl.uniprot.org/uniprot/A0A6P7GJC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the taffazin family.|||Mitochondrion inner membrane|||Mitochondrion outer membrane http://togogenome.org/gene/50390:LOC114326559 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB27 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114331841 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXN5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114327347 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7H1 ^@ Similarity|||Subunit ^@ Belongs to the LDH/MDH superfamily. MDH type 1 family.|||Homodimer. http://togogenome.org/gene/50390:LOC114341906 ^@ http://purl.uniprot.org/uniprot/A0A6P7GR42 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mitochondrion inner membrane|||Probably involved in the biogenesis of the COX complex. http://togogenome.org/gene/50390:LOC114329916 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SGF11 family.|||Component of some SAGA transcription coactivator-HAT complexes.|||Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.|||Nucleus http://togogenome.org/gene/50390:LOC114324544 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 3 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/50390:LOC114327332 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAA8 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/50390:LOC114331297 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKS4 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. http://togogenome.org/gene/50390:LOC114324410 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYH9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/50390:LOC114340817 ^@ http://purl.uniprot.org/uniprot/A0A6P7GD78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SWD2 family.|||Nucleus http://togogenome.org/gene/50390:LOC114325253 ^@ http://purl.uniprot.org/uniprot/A0A6P7F164 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 58 family.|||Membrane http://togogenome.org/gene/50390:LOC114325207 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5H4 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruB family. http://togogenome.org/gene/50390:LOC114327564 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FRG1 family.|||Cajal body|||nucleolus http://togogenome.org/gene/50390:LOC114335011 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7Z5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114336295 ^@ http://purl.uniprot.org/uniprot/A0A6P7GC56 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114333378 ^@ http://purl.uniprot.org/uniprot/A0A6P7FS12|||http://purl.uniprot.org/uniprot/A0A6P7FWH2 ^@ Similarity ^@ Belongs to the complexin/synaphin family. http://togogenome.org/gene/50390:LOC114335017 ^@ http://purl.uniprot.org/uniprot/A0A6P7G806 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL43 family. http://togogenome.org/gene/50390:LOC114330499 ^@ http://purl.uniprot.org/uniprot/A0A6P7FS68 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/50390:LOC114347636 ^@ http://purl.uniprot.org/uniprot/A0A6P7H6C7 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/50390:LOC114334481 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVF6 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/50390:LOC114331726 ^@ http://purl.uniprot.org/uniprot/A0A6P7FX53|||http://purl.uniprot.org/uniprot/A0A6P7FX60 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMP family.|||Endosome membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114324671 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4E6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XK family.|||Membrane http://togogenome.org/gene/50390:LOC114348849 ^@ http://purl.uniprot.org/uniprot/A0A6P7H0L9 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/50390:LOC114324276 ^@ http://purl.uniprot.org/uniprot/A0A6P7EY06 ^@ Similarity ^@ Belongs to the WD repeat EBI family. http://togogenome.org/gene/50390:LOC114340218 ^@ http://purl.uniprot.org/uniprot/A0A6P7GBT6 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/50390:LOC114346093 ^@ http://purl.uniprot.org/uniprot/A0A6P7GT48 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/50390:LOC114326917 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8Q9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Cytoplasm|||LSm subunits form a heteromer with a donut shape.|||P-body|||Probably involved with other LSm subunits in the general process of degradation of mRNAs. http://togogenome.org/gene/50390:LOC114329315 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 3 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/50390:LOC114333437 ^@ http://purl.uniprot.org/uniprot/A0A6P7FS36|||http://purl.uniprot.org/uniprot/A0A6P7FWD5|||http://purl.uniprot.org/uniprot/A0A6P7G231 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF5 family.|||Nucleus http://togogenome.org/gene/50390:LOC114333219 ^@ http://purl.uniprot.org/uniprot/A0A6P7FR97|||http://purl.uniprot.org/uniprot/A0A6P7FRI2|||http://purl.uniprot.org/uniprot/A0A6P7G2Q8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family.|||Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. http://togogenome.org/gene/50390:LOC114332427 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTB6 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/50390:LOC114334239 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NFX1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114335565 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYM8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/50390:LOC114336926 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2D6|||http://purl.uniprot.org/uniprot/A0A6P7G2I1|||http://purl.uniprot.org/uniprot/A0A6P7G852|||http://purl.uniprot.org/uniprot/A0A6P7GGT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPOT14 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114328761 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114329720 ^@ http://purl.uniprot.org/uniprot/A0A6P7FP26 ^@ Similarity|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Homodimer. http://togogenome.org/gene/50390:LOC114338534 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7A4 ^@ Similarity ^@ Belongs to the adenomatous polyposis coli (APC) family. http://togogenome.org/gene/50390:LOC114336774 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7K9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114332401 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP12 family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114325659 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the non-repetitive/WGA-negative nucleoporin family.|||nuclear pore complex http://togogenome.org/gene/50390:LOC114349482 ^@ http://purl.uniprot.org/uniprot/A0A6P7HJ97 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/50390:LOC114337170 ^@ http://purl.uniprot.org/uniprot/A0A6P7G329|||http://purl.uniprot.org/uniprot/A0A6P7G368|||http://purl.uniprot.org/uniprot/A0A6P7G376|||http://purl.uniprot.org/uniprot/A0A6P7G912|||http://purl.uniprot.org/uniprot/A0A6P7G916|||http://purl.uniprot.org/uniprot/A0A6P7GEI8|||http://purl.uniprot.org/uniprot/A0A6P7GEJ3|||http://purl.uniprot.org/uniprot/A0A6P7GHS0 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/50390:LOC114333357 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRW2|||http://purl.uniprot.org/uniprot/A0A6P7FW57 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/50390:LOC114337182 ^@ http://purl.uniprot.org/uniprot/A0A6P7G350 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.|||Secreted http://togogenome.org/gene/50390:LOC114327097 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDD7 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/50390:LOC114336856 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2B8 ^@ Similarity ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. http://togogenome.org/gene/50390:LOC114329981 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJA1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114328035 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAJ6 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/50390:LOC114343821 ^@ http://purl.uniprot.org/uniprot/A0A6P7GKW3|||http://purl.uniprot.org/uniprot/A0A6P7GL30|||http://purl.uniprot.org/uniprot/A0A6P7GWQ4|||http://purl.uniprot.org/uniprot/A0A6P7GXG8|||http://purl.uniprot.org/uniprot/A0A6P7GZ34 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/50390:LOC114329674 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNR4 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/50390:LOC114332539 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ91 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. http://togogenome.org/gene/50390:LOC114339446 ^@ http://purl.uniprot.org/uniprot/A0A6P7GIY0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DIM1 family.|||Nucleus|||Plays role in pre-mRNA splicing. http://togogenome.org/gene/50390:LOC114332673 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZN5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/50390:LOC114328984 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLE2 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/50390:LOC114326679 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5X9 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114331101 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJU4|||http://purl.uniprot.org/uniprot/A0A6P7FNK1|||http://purl.uniprot.org/uniprot/A0A6P7FTT2 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/50390:LOC114336009 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZZ3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.|||Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114332915 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQA0|||http://purl.uniprot.org/uniprot/A0A6P7FQH9|||http://purl.uniprot.org/uniprot/A0A6P7G091|||http://purl.uniprot.org/uniprot/A0A6P7G1I9 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/50390:LOC114340496 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCE8 ^@ Similarity ^@ Belongs to the SMP-30/CGR1 family. http://togogenome.org/gene/50390:LOC114341915 ^@ http://purl.uniprot.org/uniprot/A0A6P7GT52 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/50390:LOC114325087 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZU5 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/50390:LOC114328295 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. http://togogenome.org/gene/50390:LOC114340609 ^@ http://purl.uniprot.org/uniprot/A0A6P7GMH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. GCN5 subfamily.|||centrosome http://togogenome.org/gene/50390:LOC114335830 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4I1 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/50390:LOC114327733 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBP7|||http://purl.uniprot.org/uniprot/A0A6P7FGA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114339763 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAF3|||http://purl.uniprot.org/uniprot/A0A6P7GAQ9|||http://purl.uniprot.org/uniprot/A0A6P7GJV7|||http://purl.uniprot.org/uniprot/A0A6P7GLZ2|||http://purl.uniprot.org/uniprot/A0A6P7GR35 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anoctamin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114330295 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHQ4|||http://purl.uniprot.org/uniprot/A0A6P7FK73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transcription factor STAT family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114330837 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIY4|||http://purl.uniprot.org/uniprot/A0A6P7FSW7 ^@ Function|||Similarity ^@ Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis. http://togogenome.org/gene/50390:LOC114325142 ^@ http://purl.uniprot.org/uniprot/A0A6P7F009|||http://purl.uniprot.org/uniprot/A0A6P7F629 ^@ Similarity ^@ Belongs to the ABITRAM family.|||Belongs to the scoloptoxin-05 family. http://togogenome.org/gene/50390:LOC114338208 ^@ http://purl.uniprot.org/uniprot/A0A6P7GDR3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114332214 ^@ http://purl.uniprot.org/uniprot/A0A6P7FY79 ^@ Function ^@ Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA. http://togogenome.org/gene/50390:LOC114324352 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZD3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/50390:LOC114331412 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the patched family.|||Membrane http://togogenome.org/gene/50390:LOC114325444 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6D7 ^@ Similarity ^@ Belongs to the DRC1 family. http://togogenome.org/gene/50390:LOC114336494 ^@ http://purl.uniprot.org/uniprot/A0A6P7G174 ^@ Similarity ^@ Belongs to the LCA5 family. http://togogenome.org/gene/50390:LOC114333204 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRG5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114341395 ^@ http://purl.uniprot.org/uniprot/A0A6P7GRT2 ^@ Similarity ^@ Belongs to the SMAUG family. http://togogenome.org/gene/50390:LOC114332780 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQ57 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase e subunit family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114335795 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.|||Mitochondrion http://togogenome.org/gene/50390:LOC114345253 ^@ http://purl.uniprot.org/uniprot/A0A6P7GPP0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/50390:LOC114344373 ^@ http://purl.uniprot.org/uniprot/A0A6P7GM90 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP9 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.|||Cytoplasm http://togogenome.org/gene/50390:LOC114337224 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3D7 ^@ Function|||Subcellular Location Annotation ^@ Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.|||cell cortex|||perinuclear region http://togogenome.org/gene/50390:LOC114324962 ^@ http://purl.uniprot.org/uniprot/A0A6P7F098|||http://purl.uniprot.org/uniprot/A0A6P7F4G1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.|||Cell membrane|||Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114343732 ^@ http://purl.uniprot.org/uniprot/A0A6P7GWE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF4 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114337277 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9E8 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/50390:LOC114327151 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDK6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase g subunit family.|||Membrane|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.|||Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.|||Mitochondrion http://togogenome.org/gene/50390:LOC114331133 ^@ http://purl.uniprot.org/uniprot/A0A6P7FK93 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/50390:LOC114328878 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFG6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS12 family. http://togogenome.org/gene/50390:LOC114329240 ^@ http://purl.uniprot.org/uniprot/A0A6P7FED0|||http://purl.uniprot.org/uniprot/A0A6P7FGQ4 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114331151 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUK8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS14 family. http://togogenome.org/gene/50390:LOC114327200 ^@ http://purl.uniprot.org/uniprot/A0A088BZ29 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/50390:LOC114329569 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFE4 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/50390:LOC114334974 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8T8 ^@ Similarity ^@ Belongs to the LovG family. http://togogenome.org/gene/50390:LOC114342445 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGZ9 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family. http://togogenome.org/gene/50390:LOC114325382 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I NDUFB11 subunit family.|||Membrane http://togogenome.org/gene/50390:LOC114329393 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEV6|||http://purl.uniprot.org/uniprot/A0A6P7FH79 ^@ Similarity ^@ Belongs to the perilipin family. http://togogenome.org/gene/50390:LOC114330318 ^@ http://purl.uniprot.org/uniprot/A0A6P7FR37 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RPB8 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/50390:LOC114328197 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAA4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114327066 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDA6|||http://purl.uniprot.org/uniprot/A0A6P7FDD4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114329273 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGS7|||http://purl.uniprot.org/uniprot/A0A6P7FM97 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114341849 ^@ http://purl.uniprot.org/uniprot/A0A6P7GFN1|||http://purl.uniprot.org/uniprot/A0A6P7GQZ9 ^@ Similarity ^@ Belongs to the GPSM family. http://togogenome.org/gene/50390:LOC114326353 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAJ1 ^@ Similarity|||Subunit ^@ Belongs to the cyclin-dependent kinase 5 activator family.|||Heterodimer of a catalytic subunit and a regulatory subunit. http://togogenome.org/gene/50390:LOC114327544 ^@ http://purl.uniprot.org/uniprot/A0A6P7F889 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/50390:LOC114328491 ^@ http://purl.uniprot.org/uniprot/A0A6P7FC07 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/50390:LOC114329918 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPR4 ^@ Similarity ^@ Belongs to the synapsin family. http://togogenome.org/gene/50390:LOC114327214 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDV7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM11 family.|||Membrane|||Plays a role in mitochondrial morphogenesis. http://togogenome.org/gene/50390:LOC114329796 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPE2 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/50390:LOC114328950 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKS1|||http://purl.uniprot.org/uniprot/A0A6P7FL96 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/50390:LOC114330164 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/50390:LOC114331366 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/50390:LOC114324531 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYX8 ^@ Similarity ^@ Belongs to the WD repeat TAF5 family. http://togogenome.org/gene/50390:LOC114327879 ^@ http://purl.uniprot.org/uniprot/A0A6P7FA25|||http://purl.uniprot.org/uniprot/A0A6P7FGN5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/50390:LOC114327148 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6R9 ^@ Similarity ^@ Belongs to the PICALM/SNAP91 family. http://togogenome.org/gene/50390:LOC114325954 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2N6 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/50390:LOC114340217 ^@ http://purl.uniprot.org/uniprot/A0A6P7GNH3 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/50390:LOC114341642 ^@ http://purl.uniprot.org/uniprot/A0A6P7GF61 ^@ Subcellular Location Annotation ^@ lamellipodium http://togogenome.org/gene/50390:LOC114339586 ^@ http://purl.uniprot.org/uniprot/A0A6P7GA76 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/50390:LOC114346500 ^@ http://purl.uniprot.org/uniprot/A0A6P7GU50 ^@ Similarity ^@ Belongs to the replication factor A protein 2 family. http://togogenome.org/gene/50390:LOC114327060 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6J7|||http://purl.uniprot.org/uniprot/A0A6P7F6L7|||http://purl.uniprot.org/uniprot/A0A6P7F794|||http://purl.uniprot.org/uniprot/A0A6P7F9D9|||http://purl.uniprot.org/uniprot/A0A6P7FDC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M13 family.|||Cell membrane http://togogenome.org/gene/50390:LOC114334648 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6P8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114329558 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFD2|||http://purl.uniprot.org/uniprot/A0A6P7FHS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NIP3 family.|||Membrane http://togogenome.org/gene/50390:LOC114334820 ^@ http://purl.uniprot.org/uniprot/A0A6P7G784 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114324814 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3Q4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS13 family. http://togogenome.org/gene/50390:LOC114326909 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCP1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/50390:LOC114334043 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYE4 ^@ Similarity ^@ Belongs to the RRP15 family. http://togogenome.org/gene/50390:LOC114325995 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8E0 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/50390:LOC114331135 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJV7|||http://purl.uniprot.org/uniprot/A0A6P7FUJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/50390:LOC114330133 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJQ6 ^@ Similarity ^@ Belongs to the UPF0415 family. http://togogenome.org/gene/50390:LOC114340713 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCZ1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS26 family. http://togogenome.org/gene/50390:LOC114329224 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGN6 ^@ Similarity ^@ Belongs to the UPF0728 family. http://togogenome.org/gene/50390:LOC114328956 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDJ7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114326211 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3P8|||http://purl.uniprot.org/uniprot/A0A6P7F4E7|||http://purl.uniprot.org/uniprot/A0A6P7F4F1|||http://purl.uniprot.org/uniprot/A0A6P7F641|||http://purl.uniprot.org/uniprot/A0A6P7F647|||http://purl.uniprot.org/uniprot/A0A6P7F9K8|||http://purl.uniprot.org/uniprot/A0A6P7F9L6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nucleus http://togogenome.org/gene/50390:LOC114331370 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUW6 ^@ Similarity ^@ Belongs to the CFAP144 family. http://togogenome.org/gene/50390:LOC114324522 ^@ http://purl.uniprot.org/uniprot/A0A6P7F005|||http://purl.uniprot.org/uniprot/A0A6P7F2R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/50390:LOC114325155 ^@ http://purl.uniprot.org/uniprot/A0A6P7F025 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).|||Cytoplasm|||Homodimer.|||Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. http://togogenome.org/gene/50390:LOC114329588 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHX1 ^@ Similarity ^@ Belongs to the MAP65/ASE1 family. http://togogenome.org/gene/50390:LOC114335063 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWU9 ^@ Similarity ^@ Belongs to the MGMT family. http://togogenome.org/gene/50390:LOC114324817 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type-B carboxylesterase/lipase family.|||Synapse http://togogenome.org/gene/50390:LOC114332470 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPE3 ^@ Function|||Similarity ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. http://togogenome.org/gene/50390:LOC114327381 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7N3|||http://purl.uniprot.org/uniprot/A0A6P7FER7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114334386 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUU2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL30 family. http://togogenome.org/gene/50390:LOC114329487 ^@ http://purl.uniprot.org/uniprot/A0A6P7FN34 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114325785 ^@ http://purl.uniprot.org/uniprot/A0A6P7F261 ^@ Similarity ^@ Belongs to the NEMF family. http://togogenome.org/gene/50390:LOC114339512 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9R5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the C1D family.|||Cytoplasm|||Monomer and homodimer.|||Nucleus|||Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.|||nucleolus http://togogenome.org/gene/50390:LOC114349333 ^@ http://purl.uniprot.org/uniprot/A0A6P7H1S2 ^@ Similarity ^@ Belongs to the ZFTRAF1 family. http://togogenome.org/gene/50390:LOC114333873 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tollip family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114330031 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COA8 family.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114330227 ^@ http://purl.uniprot.org/uniprot/A0A6P7FK06 ^@ Similarity ^@ Belongs to the peptidase S28 family. http://togogenome.org/gene/50390:LOC114329665 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFQ4 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/50390:LOC114325852 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/50390:LOC114324852 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4Z3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114343504 ^@ http://purl.uniprot.org/uniprot/A0A6P7GVU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tektin family.|||flagellum http://togogenome.org/gene/50390:LOC114336732 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.|||cytoskeleton http://togogenome.org/gene/50390:LOC114338673 ^@ http://purl.uniprot.org/uniprot/A0A6P7GIP2 ^@ Function|||Similarity ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB1 subunit family. http://togogenome.org/gene/50390:LOC114326864 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5V9 ^@ Similarity ^@ Belongs to the SNAPIN family. http://togogenome.org/gene/50390:LOC114334595 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7H0 ^@ Similarity ^@ Belongs to the WD repeat THOC6 family. http://togogenome.org/gene/50390:LOC114334619 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVH2|||http://purl.uniprot.org/uniprot/A0A6P7G6L0 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/50390:LOC114325913 ^@ http://purl.uniprot.org/uniprot/A0A6P7F855 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM43 family.|||Membrane http://togogenome.org/gene/50390:LOC114332811 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Membrane http://togogenome.org/gene/50390:LOC114324579 ^@ http://purl.uniprot.org/uniprot/A0A6P7F424 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/50390:LOC114328923 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKP2|||http://purl.uniprot.org/uniprot/A0A6P7FL70 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114334398 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV56 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/50390:LOC114326749 ^@ http://purl.uniprot.org/uniprot/A0A6P7F670 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/50390:LOC114327068 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7A3|||http://purl.uniprot.org/uniprot/A0A6P7F9D4|||http://purl.uniprot.org/uniprot/A0A6P7FDB2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114326018 ^@ http://purl.uniprot.org/uniprot/A0A6P7F537|||http://purl.uniprot.org/uniprot/A0A6P7F8J1|||http://purl.uniprot.org/uniprot/A0A6P7F947 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/50390:LOC114338146 ^@ http://purl.uniprot.org/uniprot/A0A6P7G651 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL20 family. http://togogenome.org/gene/50390:LOC114331899 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMB2 ^@ Function ^@ E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates. http://togogenome.org/gene/50390:LOC114339319 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9F8 ^@ Similarity ^@ Belongs to the SZRD1 family. http://togogenome.org/gene/50390:LOC114347302 ^@ http://purl.uniprot.org/uniprot/A0A6P7HDI4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIA subunit 2 family.|||Nucleus|||TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. http://togogenome.org/gene/50390:LOC114328289 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM134/TMEM230 family.|||Membrane http://togogenome.org/gene/50390:LOC114327196 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7Q0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114326683 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7R2|||http://purl.uniprot.org/uniprot/A0A6P7FBJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Nucleus http://togogenome.org/gene/50390:LOC114328598 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBK4 ^@ Similarity ^@ Belongs to the centrin family. http://togogenome.org/gene/50390:LOC114343397 ^@ http://purl.uniprot.org/uniprot/A0A6P7GJL4|||http://purl.uniprot.org/uniprot/A0A6P7GK76|||http://purl.uniprot.org/uniprot/A0A6P7GK95|||http://purl.uniprot.org/uniprot/A0A6P7GKB5|||http://purl.uniprot.org/uniprot/A0A6P7GXH2|||http://purl.uniprot.org/uniprot/A0A6P7H205 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mical family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114324479 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYS6 ^@ Caution|||Subcellular Location Annotation|||Subunit ^@ Heterodimer of burs and pburs.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/50390:LOC114328111 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0239 family.|||Membrane http://togogenome.org/gene/50390:LOC114334157 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4U1 ^@ Similarity ^@ Belongs to the SLX4 family. http://togogenome.org/gene/50390:LOC114341488 ^@ http://purl.uniprot.org/uniprot/A0A6P7GW91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Mitochondrion intermembrane space|||Mitochondrion membrane|||Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Can antagonize antiapoptotic activity of th/Diap1 by directly inducing the degradation of th/Diap1. http://togogenome.org/gene/50390:LOC114345731 ^@ http://purl.uniprot.org/uniprot/A0A6P7H1I0 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/50390:LOC114338405 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6U1 ^@ Similarity ^@ In the C-terminal section; belongs to the MoaC family.|||In the N-terminal section; belongs to the radical SAM superfamily. MoaA family. http://togogenome.org/gene/50390:LOC114346022 ^@ http://purl.uniprot.org/uniprot/A0A6P7GSX9 ^@ Similarity ^@ Belongs to the alpha-carbonic anhydrase family. http://togogenome.org/gene/50390:LOC114337107 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the maelstrom family.|||Nucleus http://togogenome.org/gene/50390:LOC114325262 ^@ http://purl.uniprot.org/uniprot/A0A6P7F174 ^@ Similarity ^@ Belongs to the ZNF277 family. http://togogenome.org/gene/50390:LOC114329076 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDW8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/50390:LOC114331492 ^@ http://purl.uniprot.org/uniprot/A0A6P7FW69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EAF7 family.|||Nucleus http://togogenome.org/gene/50390:LOC114339180 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8U4|||http://purl.uniprot.org/uniprot/A0A6P7GI78 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/50390:LOC114326708 ^@ http://purl.uniprot.org/uniprot/A0A6P7F623 ^@ Similarity ^@ Belongs to the CFAP91 family. http://togogenome.org/gene/50390:LOC114349516 ^@ http://purl.uniprot.org/uniprot/A0A6P7H2Q5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114331413 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPV3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/50390:LOC114333245 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSC1 (TC 1.A.17) family.|||Membrane http://togogenome.org/gene/50390:LOC114336377 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/50390:LOC114340589 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glypican family.|||Cell membrane|||Cell surface proteoglycan. http://togogenome.org/gene/50390:LOC114337702 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4X5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 22 family. http://togogenome.org/gene/50390:LOC114324520 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYW2|||http://purl.uniprot.org/uniprot/A0A6P7F3V5 ^@ Caution|||Similarity ^@ Belongs to the neurexin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114326870 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.|||Nucleus http://togogenome.org/gene/50390:LOC114329300 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGV8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 22 family. http://togogenome.org/gene/50390:LOC114324851 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZ29 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/50390:LOC114329647 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFN5|||http://purl.uniprot.org/uniprot/A0A6P7FI36 ^@ Similarity ^@ Belongs to the WD repeat CDC20/Fizzy family. http://togogenome.org/gene/50390:LOC114332810 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/50390:LOC114329653 ^@ http://purl.uniprot.org/uniprot/A0A6P7FI41 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/50390:LOC114326454 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4L3 ^@ Similarity ^@ Belongs to the BicC family. http://togogenome.org/gene/50390:LOC114334512 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV69|||http://purl.uniprot.org/uniprot/A0A6P7G769 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/50390:LOC114327549 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB45 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1 family. CLIP subfamily.|||Secreted|||The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure. http://togogenome.org/gene/50390:LOC114333886 ^@ http://purl.uniprot.org/uniprot/A0A6P7G587 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114326036 ^@ http://purl.uniprot.org/uniprot/A0A6P7F346|||http://purl.uniprot.org/uniprot/A0A6P7F3A2|||http://purl.uniprot.org/uniprot/A0A6P7F3D0|||http://purl.uniprot.org/uniprot/A0A6P7F3H2|||http://purl.uniprot.org/uniprot/A0A6P7F3H6|||http://purl.uniprot.org/uniprot/A0A6P7F3I5|||http://purl.uniprot.org/uniprot/A0A6P7F3K9|||http://purl.uniprot.org/uniprot/A0A6P7F3Q8|||http://purl.uniprot.org/uniprot/A0A6P7F3S3|||http://purl.uniprot.org/uniprot/A0A6P7F3U6|||http://purl.uniprot.org/uniprot/A0A6P7F3Y9|||http://purl.uniprot.org/uniprot/A0A6P7F402|||http://purl.uniprot.org/uniprot/A0A6P7F415|||http://purl.uniprot.org/uniprot/A0A6P7F426|||http://purl.uniprot.org/uniprot/A0A6P7F475|||http://purl.uniprot.org/uniprot/A0A6P7F478|||http://purl.uniprot.org/uniprot/A0A6P7F4A7|||http://purl.uniprot.org/uniprot/A0A6P7F4F4|||http://purl.uniprot.org/uniprot/A0A6P7F4I3|||http://purl.uniprot.org/uniprot/A0A6P7F588|||http://purl.uniprot.org/uniprot/A0A6P7F5S2|||http://purl.uniprot.org/uniprot/A0A6P7F5T8|||http://purl.uniprot.org/uniprot/A0A6P7F5U8|||http://purl.uniprot.org/uniprot/A0A6P7F621|||http://purl.uniprot.org/uniprot/A0A6P7F667|||http://purl.uniprot.org/uniprot/A0A6P7F8N3|||http://purl.uniprot.org/uniprot/A0A6P7F8U9|||http://purl.uniprot.org/uniprot/A0A6P7F8W8|||http://purl.uniprot.org/uniprot/A0A6P7F9G5|||http://purl.uniprot.org/uniprot/A0A6P7F9N6|||http://purl.uniprot.org/uniprot/A0A6P7F9W0|||http://purl.uniprot.org/uniprot/A0A6P7F9Z1|||http://purl.uniprot.org/uniprot/A0A6P7FA03|||http://purl.uniprot.org/uniprot/A0A6P7FA33 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/50390:LOC114328742 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJZ6|||http://purl.uniprot.org/uniprot/A0A6P7FKK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BLOC1S5 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114327884 ^@ http://purl.uniprot.org/uniprot/A0A6P7FC56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.|||In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.|||Nucleus http://togogenome.org/gene/50390:LOC114324517 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYV6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114341815 ^@ http://purl.uniprot.org/uniprot/A0A6P7GX80 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/50390:LOC114332308 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleoporin interacting component (NIC) family.|||nuclear pore complex http://togogenome.org/gene/50390:LOC114336371 ^@ http://purl.uniprot.org/uniprot/A0A6P7G690 ^@ Function|||Similarity ^@ Belongs to the diphosphomevalonate decarboxylase family.|||Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis. http://togogenome.org/gene/50390:LOC114349491 ^@ http://purl.uniprot.org/uniprot/A0A6P7HJB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELOF1 family.|||Nucleus|||Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. http://togogenome.org/gene/50390:LOC114333683 ^@ http://purl.uniprot.org/uniprot/A0A6P7G331 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 14 family. XylT subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/50390:LOC114328091 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCW2 ^@ Similarity ^@ Belongs to the calreticulin family. http://togogenome.org/gene/50390:LOC114338766 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7Y5 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/50390:LOC114335983 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZP6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL13 family. http://togogenome.org/gene/50390:LOC114324524 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3V9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114333043 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVC3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. http://togogenome.org/gene/50390:LOC114324619 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYH4|||http://purl.uniprot.org/uniprot/A0A6P7F345 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ninjurin family.|||Membrane http://togogenome.org/gene/50390:LOC114327885 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPF27 family.|||Nucleus http://togogenome.org/gene/50390:LOC114332948 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQE8 ^@ Similarity ^@ Belongs to the DDIT4 family. http://togogenome.org/gene/50390:LOC114327016 ^@ http://purl.uniprot.org/uniprot/A0A6P7F970 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/50390:LOC114327220 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9U4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114326400 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114335543 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the NDC80/HEC1 family.|||Component of the NDC80 complex.|||Nucleus|||kinetochore http://togogenome.org/gene/50390:LOC114338791 ^@ http://purl.uniprot.org/uniprot/A0A6P7GH06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/50390:LOC114336132 ^@ http://purl.uniprot.org/uniprot/A0A6P7GDL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GRINL1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114332092 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMS9 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1 family. CLIP subfamily.|||Secreted|||The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure. http://togogenome.org/gene/50390:LOC114338141 ^@ http://purl.uniprot.org/uniprot/A0A6P7G655 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/50390:LOC114331766 ^@ http://purl.uniprot.org/uniprot/A0A6P7FR09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS33 family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114326998 ^@ http://purl.uniprot.org/uniprot/A0A6P7F732|||http://purl.uniprot.org/uniprot/A0A6P7FD28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIG1 family.|||Membrane http://togogenome.org/gene/50390:LOC114339334 ^@ http://purl.uniprot.org/uniprot/A0A6P7GPT0 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/50390:LOC114330783 ^@ http://purl.uniprot.org/uniprot/A0A6P7FM65 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the hook family.|||Endosome|||Homodimer. Interacts with microtubules via its N-terminus.|||cytoskeleton http://togogenome.org/gene/50390:LOC114324882 ^@ http://purl.uniprot.org/uniprot/A0A6P7F546 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/50390:LOC114331671 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.|||Membrane http://togogenome.org/gene/50390:LOC114330887 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJH4 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/50390:LOC114330123 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGR8|||http://purl.uniprot.org/uniprot/A0A6P7FQQ5 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/50390:LOC114326905 ^@ http://purl.uniprot.org/uniprot/A0A6P7F600 ^@ Similarity ^@ Belongs to the peptidase M24 family. http://togogenome.org/gene/50390:LOC114349365 ^@ http://purl.uniprot.org/uniprot/A0A6P7HA34 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114325637 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3X3 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/50390:LOC114330409 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRU1 ^@ Function|||Similarity ^@ Belongs to the SPSB family.|||May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. http://togogenome.org/gene/50390:LOC114329435 ^@ http://purl.uniprot.org/uniprot/A0A6P7FE99|||http://purl.uniprot.org/uniprot/A0A6P7FF01|||http://purl.uniprot.org/uniprot/A0A6P7FHD2|||http://purl.uniprot.org/uniprot/A0A6P7FMT4|||http://purl.uniprot.org/uniprot/A0A6P7FMT9|||http://purl.uniprot.org/uniprot/A0A6P7FMW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/50390:LOC114327175 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6U9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TADA1 family.|||Nucleus|||Probably involved in transcriptional regulation. http://togogenome.org/gene/50390:LOC114341439 ^@ http://purl.uniprot.org/uniprot/A0A6P7GPR3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS8 family. http://togogenome.org/gene/50390:LOC114344341 ^@ http://purl.uniprot.org/uniprot/A0A6P7GMZ4 ^@ Similarity ^@ Belongs to the small GTPase superfamily. SAR1 family. http://togogenome.org/gene/50390:LOC114327092 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 8 family.|||Endoplasmic reticulum lumen http://togogenome.org/gene/50390:LOC114324565 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZ12|||http://purl.uniprot.org/uniprot/A0A6P7F412 ^@ Similarity ^@ Belongs to the MAGUK family. http://togogenome.org/gene/50390:LOC114329663 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNW5 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/50390:LOC114327433 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8K4|||http://purl.uniprot.org/uniprot/A0A6P7FAP2 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114349434 ^@ http://purl.uniprot.org/uniprot/A0A6P7H262 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/50390:LOC114332920 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1N7 ^@ Function|||Similarity ^@ Belongs to the BLOC1S6 family.|||Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis. http://togogenome.org/gene/50390:LOC114334795 ^@ http://purl.uniprot.org/uniprot/A0A6P7G820 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the timeless family.|||Nucleus http://togogenome.org/gene/50390:LOC114330889 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJ43 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/50390:LOC114329716 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Membrane http://togogenome.org/gene/50390:LOC114334040 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5P4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS3/PSF3 family.|||Component of the GINS complex.|||Nucleus|||The GINS complex plays an essential role in the initiation of DNA replication. http://togogenome.org/gene/50390:LOC114327509 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFB8 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/50390:LOC114338955 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BCL9 family.|||Nucleus http://togogenome.org/gene/50390:LOC114330121 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HDGF family.|||Nucleus http://togogenome.org/gene/50390:LOC114335560 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYM2 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114324934 ^@ http://purl.uniprot.org/uniprot/A0A6P7F058 ^@ Similarity ^@ Belongs to the GCF family. http://togogenome.org/gene/50390:LOC114333700 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSQ3 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/50390:LOC114338019 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5U8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMCO4 family.|||Membrane http://togogenome.org/gene/50390:LOC114333216 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2P5 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/50390:LOC114331959 ^@ http://purl.uniprot.org/uniprot/A0A6P7FX46 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114336067 ^@ http://purl.uniprot.org/uniprot/A0A6P7G063 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the enhancer of polycomb family.|||Nucleus http://togogenome.org/gene/50390:LOC114325906 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2J1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CSN7/EIF3M family. CSN7 subfamily.|||Belongs to the eIF-3 subunit M family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/50390:LOC114331034 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJY9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114342623 ^@ http://purl.uniprot.org/uniprot/A0A6P7GHD2|||http://purl.uniprot.org/uniprot/A0A6P7GHF5|||http://purl.uniprot.org/uniprot/A0A6P7GT95 ^@ Function|||Similarity ^@ Belongs to the 5'-AMP-activated protein kinase beta subunit family.|||Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). http://togogenome.org/gene/50390:LOC114338967 ^@ http://purl.uniprot.org/uniprot/A0A4D6Q5Y3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 45 (cellulase K) family. http://togogenome.org/gene/50390:LOC114339390 ^@ http://purl.uniprot.org/uniprot/A0A6P7GKU0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114325848 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/50390:LOC114332264 ^@ http://purl.uniprot.org/uniprot/A0A6P7FND9 ^@ Similarity ^@ Belongs to the MIF family. http://togogenome.org/gene/50390:LOC114341282 ^@ http://purl.uniprot.org/uniprot/A0A6P7GPC3 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).|||Endosome membrane|||Late endosome membrane|||Lysosome membrane|||Membrane http://togogenome.org/gene/50390:LOC114325250 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2F4 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. http://togogenome.org/gene/50390:LOC114338379 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6S9|||http://purl.uniprot.org/uniprot/A0A6P7GHY3 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily. http://togogenome.org/gene/50390:LOC114349465 ^@ http://purl.uniprot.org/uniprot/A0A6P7HAE7 ^@ Similarity ^@ Belongs to the FAM136 family. http://togogenome.org/gene/50390:LOC114342408 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM201 family.|||Membrane|||Nucleus inner membrane http://togogenome.org/gene/50390:LOC114343773 ^@ http://purl.uniprot.org/uniprot/A0A6P7GYA8 ^@ Similarity ^@ Belongs to the vacuolar ATPase subunit S1 family. http://togogenome.org/gene/50390:LOC114332574 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTQ9 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114329083 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MESD family.|||Endoplasmic reticulum http://togogenome.org/gene/50390:LOC114325774 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2Y8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114330690 ^@ http://purl.uniprot.org/uniprot/A0A6P7FII0|||http://purl.uniprot.org/uniprot/A0A6P7FIZ4|||http://purl.uniprot.org/uniprot/A0A6P7FLV1|||http://purl.uniprot.org/uniprot/A0A6P7FSE1 ^@ Similarity ^@ Belongs to the SERBP1-HABP4 family. http://togogenome.org/gene/50390:LOC114324840 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4X7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nucleoporin Nup85 family.|||Component of the nuclear pore complex (NPC).|||Functions as a component of the nuclear pore complex (NPC).|||Nucleus membrane|||nuclear pore complex http://togogenome.org/gene/50390:LOC114324638 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0C1 ^@ Similarity ^@ Belongs to the formin homology family. http://togogenome.org/gene/50390:LOC114327770 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8Z6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX16 family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114326327 ^@ http://purl.uniprot.org/uniprot/A0A6P7FA26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBP family.|||Nucleus http://togogenome.org/gene/50390:LOC114349453 ^@ http://purl.uniprot.org/uniprot/A0A6P7HJ57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114332675 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPR5|||http://purl.uniprot.org/uniprot/A0A6P7G0Z4 ^@ Similarity ^@ Belongs to the TECPR1 family. http://togogenome.org/gene/50390:LOC114328577 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJ90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat fritz family.|||Cell membrane|||Membrane|||cilium axoneme http://togogenome.org/gene/50390:LOC114331372 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKN1|||http://purl.uniprot.org/uniprot/A0A6P7FKP7|||http://purl.uniprot.org/uniprot/A0A6P7FL17|||http://purl.uniprot.org/uniprot/A0A6P7FL27|||http://purl.uniprot.org/uniprot/A0A6P7FL36|||http://purl.uniprot.org/uniprot/A0A6P7FPN7|||http://purl.uniprot.org/uniprot/A0A6P7FPP2|||http://purl.uniprot.org/uniprot/A0A6P7FUY2|||http://purl.uniprot.org/uniprot/A0A6P7FVG4|||http://purl.uniprot.org/uniprot/A0A6P7FVH0|||http://purl.uniprot.org/uniprot/A0A6P7FVH5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/50390:LOC114326399 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6U2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS12 family. http://togogenome.org/gene/50390:LOC114326464 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5A4|||http://purl.uniprot.org/uniprot/A0A6P7FAM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the pex2/pex10/pex12 family.|||Membrane|||Peroxisome membrane http://togogenome.org/gene/50390:LOC114347281 ^@ http://purl.uniprot.org/uniprot/A0A6P7GWC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114334175 ^@ http://purl.uniprot.org/uniprot/A0A6P7FU94|||http://purl.uniprot.org/uniprot/A0A6P7G676 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/50390:LOC114332829 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQ38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family.|||Nucleus http://togogenome.org/gene/50390:LOC114343906 ^@ http://purl.uniprot.org/uniprot/A0A6P7GYN8|||http://purl.uniprot.org/uniprot/A0A6P7H3F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 16 (GT16) protein family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/50390:LOC114325608 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2C3 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/50390:LOC114336375 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/50390:LOC114324613 ^@ http://purl.uniprot.org/uniprot/A0A6P7F096 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Cytoplasmic vesicle membrane|||Golgi apparatus membrane|||Membrane|||Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity. http://togogenome.org/gene/50390:LOC114331351 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPJ8 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase family. http://togogenome.org/gene/50390:LOC114329058 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDV4 ^@ Similarity|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/50390:LOC114334375 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c-type heme lyase family.|||Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114324781 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4N4 ^@ Caution|||Function|||Similarity ^@ Belongs to the acetyltransferase ATAT1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. http://togogenome.org/gene/50390:LOC114342097 ^@ http://purl.uniprot.org/uniprot/A0A6P7GG61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fascin family.|||cytoskeleton http://togogenome.org/gene/50390:LOC114330884 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJG8|||http://purl.uniprot.org/uniprot/A0A6P7FTL6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114348305 ^@ http://purl.uniprot.org/uniprot/A0A6P7HG53 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114326180 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5Y0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM47 family.|||Membrane http://togogenome.org/gene/50390:LOC114325509 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1A3 ^@ Similarity ^@ Belongs to the TBP family. http://togogenome.org/gene/50390:LOC114333010 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0L5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/50390:LOC114338224 ^@ http://purl.uniprot.org/uniprot/A0A6P7GLG5 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/50390:LOC114325274 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114333827 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXR9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cytoplasmic vesicle membrane|||Membrane|||Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. http://togogenome.org/gene/50390:LOC114333239 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/50390:LOC114330618 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIR4|||http://purl.uniprot.org/uniprot/A0A6P7FSP8 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B family. http://togogenome.org/gene/50390:LOC114347312 ^@ http://purl.uniprot.org/uniprot/A0A6P7HDJ4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. http://togogenome.org/gene/50390:LOC114332606 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPT8 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX41 subfamily. http://togogenome.org/gene/50390:LOC114331035 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Belongs to the scoloptoxin-05 family.|||Membrane http://togogenome.org/gene/50390:LOC114338498 ^@ http://purl.uniprot.org/uniprot/A0A6P7GF67 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/50390:LOC114329241 ^@ http://purl.uniprot.org/uniprot/A0A6P7FM68 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114326142 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114325838 ^@ http://purl.uniprot.org/uniprot/A0A6P7F344 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/50390:LOC114342875 ^@ http://purl.uniprot.org/uniprot/A0A6P7GIC1|||http://purl.uniprot.org/uniprot/A0A6P7H0B6 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. Torsin subfamily. http://togogenome.org/gene/50390:LOC114343072 ^@ http://purl.uniprot.org/uniprot/A0A6P7GUJ2|||http://purl.uniprot.org/uniprot/A0A6P7GWB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Early endosome membrane|||Endosome|||phagosome|||trans-Golgi network membrane http://togogenome.org/gene/50390:LOC114330885 ^@ http://purl.uniprot.org/uniprot/A0A6P7FML3 ^@ Similarity ^@ Belongs to the peptidase S8 family. Furin subfamily. http://togogenome.org/gene/50390:LOC114331009 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/50390:LOC114324252 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZ39 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme c group covalently per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114328538 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJ34 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/50390:LOC114340706 ^@ http://purl.uniprot.org/uniprot/A0A6P7GQ06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPEG family.|||Membrane http://togogenome.org/gene/50390:LOC114347339 ^@ http://purl.uniprot.org/uniprot/A0A6P7HDL8 ^@ Subcellular Location Annotation ^@ Chromosome|||Nucleus http://togogenome.org/gene/50390:LOC114329861 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPN9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL28 family. http://togogenome.org/gene/50390:LOC114340343 ^@ http://purl.uniprot.org/uniprot/A0A6P7GLR4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114325857 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7Y5 ^@ Similarity ^@ Belongs to the D-glucuronyl C5-epimerase family. http://togogenome.org/gene/50390:LOC114344260 ^@ http://purl.uniprot.org/uniprot/A0A6P7GMP1|||http://purl.uniprot.org/uniprot/A0A6P7H4I5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the protein kinase superfamily. PAN3 family.|||Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.|||Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein (via PABC domain), conferring substrate specificity of the enzyme complex.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||P-body|||Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.|||The N-terminal zinc finger binds to poly(A) RNA.|||The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2. http://togogenome.org/gene/50390:LOC114331032 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJM4 ^@ Similarity ^@ Belongs to the canopy family. http://togogenome.org/gene/50390:LOC114339453 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9L4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ATPase B chain family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114327392 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZFPL1 family.|||Membrane http://togogenome.org/gene/50390:LOC114327676 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBH7|||http://purl.uniprot.org/uniprot/A0A6P7FG21 ^@ Caution|||Similarity ^@ Belongs to the peptidase C2 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114338457 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6Z4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/50390:LOC114336734 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1Y6 ^@ Function|||Similarity ^@ Belongs to the EAF family.|||Promotes transcriptional elongation by Su(Tpl)/ELL. Essential for development. http://togogenome.org/gene/50390:LOC114324527 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2R9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114330084 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJL2 ^@ Similarity ^@ Belongs to the tektin family. http://togogenome.org/gene/50390:LOC114332559 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZC6 ^@ Similarity ^@ Belongs to the NSRP1 family. http://togogenome.org/gene/50390:LOC114338180 ^@ http://purl.uniprot.org/uniprot/A0A6P7GDK4 ^@ Similarity|||Subunit ^@ Belongs to the complex I NDUFB5 subunit family.|||Complex I is composed of 45 different subunits. http://togogenome.org/gene/50390:LOC114328991 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKX9 ^@ Similarity ^@ Belongs to the SEN15 family. http://togogenome.org/gene/50390:LOC114342112 ^@ http://purl.uniprot.org/uniprot/A0A6P7GY39 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/50390:LOC114332576 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPC1 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114327125 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9I2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCDC47 family.|||Rough endoplasmic reticulum membrane http://togogenome.org/gene/50390:LOC114336364 ^@ http://purl.uniprot.org/uniprot/A0A6P7GEJ1 ^@ Similarity ^@ Belongs to the eIF4E-binding protein family. http://togogenome.org/gene/50390:LOC114327221 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDX2|||http://purl.uniprot.org/uniprot/A0A6P7FDX8 ^@ Similarity ^@ Belongs to the SMG9 family. http://togogenome.org/gene/50390:LOC114326913 ^@ http://purl.uniprot.org/uniprot/A0A6P7F607 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114326302 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAB7|||http://purl.uniprot.org/uniprot/A0A6P7FAC5 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/50390:LOC114330523 ^@ http://purl.uniprot.org/uniprot/A0A6P7FID1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Endosome membrane|||Membrane http://togogenome.org/gene/50390:LOC114332571 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZD1 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114325105 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5X8 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/50390:LOC114326553 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7C7 ^@ Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/50390:LOC114326916 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6Q6 ^@ Function|||Similarity ^@ Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.|||Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8. http://togogenome.org/gene/50390:LOC114329085 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SDHAF2 family.|||Interacts with the flavoprotein subunit within the SDH catalytic dimer.|||Mitochondrion matrix|||Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. http://togogenome.org/gene/50390:LOC114325110 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0P9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC3 family.|||Membrane http://togogenome.org/gene/50390:LOC114334796 ^@ http://purl.uniprot.org/uniprot/A0A6P7FW93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA10 subunit family.|||Mitochondrion matrix http://togogenome.org/gene/50390:LOC114343564 ^@ http://purl.uniprot.org/uniprot/A0A6P7GJW4|||http://purl.uniprot.org/uniprot/A0A6P7GVZ8|||http://purl.uniprot.org/uniprot/A0A6P7GXR7|||http://purl.uniprot.org/uniprot/A0A6P7H2D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM CPSF6/7 family.|||Nucleus http://togogenome.org/gene/50390:LOC114349374 ^@ http://purl.uniprot.org/uniprot/A0A6P7H214 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.|||Nucleus http://togogenome.org/gene/50390:LOC114327316 ^@ http://purl.uniprot.org/uniprot/A0A6P7FA87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GAPVD1 family.|||Membrane http://togogenome.org/gene/50390:LOC114337761 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4Y0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 9 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/50390:LOC114333957 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTW7 ^@ Similarity ^@ Belongs to the SINA (Seven in absentia) family. http://togogenome.org/gene/50390:LOC114348551 ^@ http://purl.uniprot.org/uniprot/A0A6P7HGV0|||http://purl.uniprot.org/uniprot/A0A6P7HGV5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114333550 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3U5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114338388 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6S6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase A22A family.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Homodimer.|||Membrane|||Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.|||The PAL motif is required for normal active site conformation. http://togogenome.org/gene/50390:LOC114333246 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRC7|||http://purl.uniprot.org/uniprot/A0A6P7G1J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114324807 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZN6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dolichyldiphosphatase family.|||Membrane|||Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate. http://togogenome.org/gene/50390:LOC114333784 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/50390:LOC114327095 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114326139 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAPT1 family.|||Membrane http://togogenome.org/gene/50390:LOC114348372 ^@ http://purl.uniprot.org/uniprot/A0A6P7HAQ2|||http://purl.uniprot.org/uniprot/A0A6P7HGH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPL family. K-HECT subfamily.|||nucleoplasm http://togogenome.org/gene/50390:LOC114332918 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1L0 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/50390:LOC114326243 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9S1 ^@ Similarity ^@ Belongs to the acetyltransferase family. NAA60 subfamily. http://togogenome.org/gene/50390:LOC114340208 ^@ http://purl.uniprot.org/uniprot/A0A6P7GLB6 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/50390:LOC114332268 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNE9|||http://purl.uniprot.org/uniprot/A0A6P7FNV5|||http://purl.uniprot.org/uniprot/A0A6P7FYF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/50390:LOC114333250 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2U0 ^@ Subcellular Location Annotation ^@ Peroxisome http://togogenome.org/gene/50390:LOC114328576 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEL6 ^@ Similarity ^@ Belongs to the CCDC53 family. http://togogenome.org/gene/50390:LOC114330141 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQI3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114335299 ^@ http://purl.uniprot.org/uniprot/A0A6P7G921 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114333105 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0Y7 ^@ Similarity ^@ Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. http://togogenome.org/gene/50390:LOC114328918 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKM4 ^@ Similarity ^@ Belongs to the EMC8/EMC9 family. http://togogenome.org/gene/50390:LOC114345661 ^@ http://purl.uniprot.org/uniprot/A0A6P7GRV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/50390:LOC114330836 ^@ http://purl.uniprot.org/uniprot/A0A6P7FME2 ^@ Similarity ^@ Belongs to the vasopressin/oxytocin family. http://togogenome.org/gene/50390:LOC114331044 ^@ http://purl.uniprot.org/uniprot/A0A6P7FK03|||http://purl.uniprot.org/uniprot/A0A6P7FNE1|||http://purl.uniprot.org/uniprot/A0A6P7FU96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114335671 ^@ http://purl.uniprot.org/uniprot/A0A6P7GBM3 ^@ Similarity ^@ Belongs to the TTC27 family. http://togogenome.org/gene/50390:LOC114324458 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2J9 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/50390:LOC114325138 ^@ http://purl.uniprot.org/uniprot/A0A6P7F619 ^@ Function|||Similarity ^@ Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.|||E1-like enzyme which activates UFM1. http://togogenome.org/gene/50390:LOC114328732 ^@ http://purl.uniprot.org/uniprot/A0A6P7FC09|||http://purl.uniprot.org/uniprot/A0A6P7FCT9|||http://purl.uniprot.org/uniprot/A0A6P7FF33|||http://purl.uniprot.org/uniprot/A0A6P7FJY0|||http://purl.uniprot.org/uniprot/A0A6P7FKI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114333021 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1Z0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits. http://togogenome.org/gene/50390:LOC114335282 ^@ http://purl.uniprot.org/uniprot/A0A6P7GA22 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/50390:LOC114330533 ^@ http://purl.uniprot.org/uniprot/A0A6P7FI07|||http://purl.uniprot.org/uniprot/A0A6P7FIJ0|||http://purl.uniprot.org/uniprot/A0A6P7FL75|||http://purl.uniprot.org/uniprot/A0A6P7FRU5|||http://purl.uniprot.org/uniprot/A0A6P7FSI2|||http://purl.uniprot.org/uniprot/A0A6P7FSI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.|||Cell membrane http://togogenome.org/gene/50390:LOC114342409 ^@ http://purl.uniprot.org/uniprot/A0A6P7GYZ8 ^@ Function ^@ Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. http://togogenome.org/gene/50390:LOC114339528 ^@ http://purl.uniprot.org/uniprot/A0A6P7GQD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin beta chain family.|||Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114324411 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2C6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 13 family.|||Golgi apparatus membrane|||Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.|||Membrane|||The cofactor is mostly bound to the substrate. http://togogenome.org/gene/50390:LOC114329298 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEI3 ^@ Similarity|||Subunit ^@ Belongs to the DapA family.|||Homotetramer. http://togogenome.org/gene/50390:LOC114332205 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNN0 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/50390:LOC114335598 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3Q0|||http://purl.uniprot.org/uniprot/A0A6P7GA07|||http://purl.uniprot.org/uniprot/A0A6P7GB54 ^@ Similarity ^@ Belongs to the IAP family. http://togogenome.org/gene/50390:LOC114331493 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVC0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. http://togogenome.org/gene/50390:LOC114326880 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6M0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114337757 ^@ http://purl.uniprot.org/uniprot/A0A6P7GBH6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NADP-dependent oxidoreductase L4BD family.|||Cytoplasm|||Monomer or homodimer. http://togogenome.org/gene/50390:LOC114334618 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0A7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114347204 ^@ http://purl.uniprot.org/uniprot/A0A6P7GVG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114333234 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2S7 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114326710 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBZ2 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/50390:LOC114333628 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSS4|||http://purl.uniprot.org/uniprot/A0A6P7G461 ^@ Similarity ^@ Belongs to the UPF0585 family. http://togogenome.org/gene/50390:LOC114334497 ^@ http://purl.uniprot.org/uniprot/A0A6P7G751 ^@ Similarity ^@ Belongs to the SAP30 family. http://togogenome.org/gene/50390:LOC114335762 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ94 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NIP7 family.|||Interacts with pre-ribosome complex.|||Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.|||nucleolus http://togogenome.org/gene/50390:LOC114329117 ^@ http://purl.uniprot.org/uniprot/A0A6P7FE02 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/50390:LOC114329048 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/50390:LOC114331547 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLN2 ^@ Similarity ^@ Belongs to the SPT20 family. http://togogenome.org/gene/50390:LOC114349447 ^@ http://purl.uniprot.org/uniprot/A0A6P7HDD7 ^@ Similarity ^@ Belongs to the RRP7 family. http://togogenome.org/gene/50390:LOC114328548 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEH6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the proteasome subunit S1 family.|||Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).|||Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. http://togogenome.org/gene/50390:LOC114339977 ^@ http://purl.uniprot.org/uniprot/A0A6P7GKI2 ^@ Caution|||Cofactor ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114334292 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZC9 ^@ Function|||Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.|||Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. http://togogenome.org/gene/50390:LOC114325271 ^@ http://purl.uniprot.org/uniprot/A0A6P7F188 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family.|||Secreted http://togogenome.org/gene/50390:LOC114333617 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSQ0 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114329934 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPY1 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/50390:LOC114326245 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4J6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.|||Cytoplasm|||Heterodimer of a catalytic subunit and an accessory subunit. http://togogenome.org/gene/50390:LOC114331104 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJT5 ^@ Similarity ^@ Belongs to the HAT1 family. http://togogenome.org/gene/50390:LOC114326340 ^@ http://purl.uniprot.org/uniprot/A0A6P7F471 ^@ Function|||Similarity ^@ Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.|||Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. http://togogenome.org/gene/50390:LOC114329727 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIC8|||http://purl.uniprot.org/uniprot/A0A6P7FP34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114335290 ^@ http://purl.uniprot.org/uniprot/A0A6P7G921 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114327362 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8A3|||http://purl.uniprot.org/uniprot/A0A6P7FAD8|||http://purl.uniprot.org/uniprot/A0A6P7FEK3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/50390:LOC114338337 ^@ http://purl.uniprot.org/uniprot/A0A6P7GEE9 ^@ Similarity ^@ In the N-terminal section; belongs to the FGAMS family. http://togogenome.org/gene/50390:LOC114331148 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/50390:LOC114335710 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAE2 ^@ Similarity ^@ Belongs to the glucose-6-phosphate 1-epimerase family. http://togogenome.org/gene/50390:LOC114343505 ^@ http://purl.uniprot.org/uniprot/A0A6P7GXJ8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114334525 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVK4 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/50390:LOC114330791 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJ69 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles.|||Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type and beta-type subunits), a medium adaptin (mu-type subunit) and a small adaptin (sigma-type subunit).|||Belongs to the adaptor complexes large subunit family.|||coated pit http://togogenome.org/gene/50390:LOC114347323 ^@ http://purl.uniprot.org/uniprot/A0A6P7GWJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/50390:LOC114344090 ^@ http://purl.uniprot.org/uniprot/A0A6P7H409 ^@ Similarity ^@ Belongs to the TRM112 family. http://togogenome.org/gene/50390:LOC114336051 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZW2 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/50390:LOC114325226 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6F5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uL18 family.|||Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.|||Cytoplasm http://togogenome.org/gene/50390:LOC114329052 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCZ0|||http://purl.uniprot.org/uniprot/A0A6P7FG30|||http://purl.uniprot.org/uniprot/A0A6P7FLK8 ^@ Similarity ^@ Belongs to the ZC3H12 family. http://togogenome.org/gene/50390:LOC114328026 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9P2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/50390:LOC114333165 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2I9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114325847 ^@ http://purl.uniprot.org/uniprot/A0A6P7F350 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/50390:LOC114333902 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTE2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/50390:LOC114330604 ^@ http://purl.uniprot.org/uniprot/A0A6P7FI83|||http://purl.uniprot.org/uniprot/A0A6P7FI88|||http://purl.uniprot.org/uniprot/A0A6P7FIQ9|||http://purl.uniprot.org/uniprot/A0A6P7FS44|||http://purl.uniprot.org/uniprot/A0A6P7FSN7 ^@ Similarity ^@ Belongs to the NAD kinase family. http://togogenome.org/gene/50390:LOC114325280 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5Q3 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/50390:LOC114324616 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYG9 ^@ Similarity ^@ Belongs to the dus family. Dus3 subfamily. http://togogenome.org/gene/50390:LOC114330510 ^@ http://purl.uniprot.org/uniprot/A0A6P7FS80 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114339950 ^@ http://purl.uniprot.org/uniprot/A0A6P7GMM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GFRP family.|||Membrane|||Nucleus membrane|||cytosol http://togogenome.org/gene/50390:LOC114329652 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFN8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.|||Belongs to the carbohydrate kinase PfkB family.|||Binds 3 Mg(2+) ions per subunit.|||Monomer.|||Nucleus http://togogenome.org/gene/50390:LOC114328037 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9P9|||http://purl.uniprot.org/uniprot/A0A6P7FCQ7|||http://purl.uniprot.org/uniprot/A0A6P7FH93 ^@ Subcellular Location Annotation ^@ P-body http://togogenome.org/gene/50390:LOC114335514 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYI6 ^@ Similarity ^@ Belongs to the RANBP9/10 family. http://togogenome.org/gene/50390:LOC114329793 ^@ http://purl.uniprot.org/uniprot/A0A6P7FG41 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COQ9 family.|||Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.|||Mitochondrion http://togogenome.org/gene/50390:LOC114327798 ^@ http://purl.uniprot.org/uniprot/A0A6P7F923 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/50390:LOC114335815 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ93 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114330174 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQM8 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Fibrillarin family. http://togogenome.org/gene/50390:LOC114336648 ^@ http://purl.uniprot.org/uniprot/A0A6P7GFL1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM208 family.|||Endoplasmic reticulum membrane|||May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.|||Membrane http://togogenome.org/gene/50390:LOC114328136 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHZ2 ^@ Similarity ^@ Belongs to the TCTP family. http://togogenome.org/gene/50390:LOC114329073 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLN1 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/50390:LOC114327254 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9X7 ^@ Similarity ^@ Belongs to the CDK5RAP3 family. http://togogenome.org/gene/50390:LOC114324187 ^@ http://purl.uniprot.org/uniprot/A0A6P7EX79 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the APP family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114341628 ^@ http://purl.uniprot.org/uniprot/A0A6P7GSH7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114337471 ^@ http://purl.uniprot.org/uniprot/A0A6P7GFD7 ^@ Similarity ^@ Belongs to the alpha-carbonic anhydrase family. http://togogenome.org/gene/50390:LOC114324912 ^@ http://purl.uniprot.org/uniprot/A0A6P7F035 ^@ Similarity ^@ Belongs to the SEC2 family. http://togogenome.org/gene/50390:LOC114328971 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDL6 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/50390:LOC114327489 ^@ http://purl.uniprot.org/uniprot/A0A6P7FF08 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/50390:LOC114330886 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTM4 ^@ Similarity ^@ Belongs to the AATF family. http://togogenome.org/gene/50390:LOC114330201 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/50390:LOC114333785 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTE9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS12 family. http://togogenome.org/gene/50390:LOC114325844 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2C7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/50390:LOC114334465 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. Jun subfamily.|||Nucleus http://togogenome.org/gene/50390:LOC114337663 ^@ http://purl.uniprot.org/uniprot/A0A6P7GJM1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114324241 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2U0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the insulin family.|||Heterodimer of a B chain and an A chain linked by two disulfide bonds.|||Secreted http://togogenome.org/gene/50390:LOC114327414 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SID1 family.|||Membrane http://togogenome.org/gene/50390:LOC114333423 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRU9|||http://purl.uniprot.org/uniprot/A0A6P7G216 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/50390:LOC114328066 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114328288 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBE9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114324349 ^@ http://purl.uniprot.org/uniprot/A0A6P7F212 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/50390:LOC114333418 ^@ http://purl.uniprot.org/uniprot/A0A6P7G212|||http://purl.uniprot.org/uniprot/A0A6P7G3E3 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/50390:LOC114330974 ^@ http://purl.uniprot.org/uniprot/A0A6P7FN49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCTS1 family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114338020 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glypican family.|||Cell membrane|||Cell surface proteoglycan. http://togogenome.org/gene/50390:LOC114340033 ^@ http://purl.uniprot.org/uniprot/A0A6P7GRV5 ^@ Similarity ^@ Belongs to the SAS10 family. http://togogenome.org/gene/50390:LOC114334385 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5L2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/50390:LOC114326990 ^@ http://purl.uniprot.org/uniprot/A0A6P7FD18 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/50390:LOC114327395 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7R1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes small subunit family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. http://togogenome.org/gene/50390:LOC114334549 ^@ http://purl.uniprot.org/uniprot/A0A6P7G037|||http://purl.uniprot.org/uniprot/A0A6P7G7B2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endophilin family.|||Membrane|||Required presynaptically at the neuromuscular junction. Implicated in synaptic vesicle endocytosis. http://togogenome.org/gene/50390:LOC114344036 ^@ http://purl.uniprot.org/uniprot/A0A6P7GL82 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/50390:LOC114338617 ^@ http://purl.uniprot.org/uniprot/A0A6P7GIJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lin-54 family.|||Nucleus http://togogenome.org/gene/50390:LOC114344529 ^@ http://purl.uniprot.org/uniprot/A0A6P7GYG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEN-2 family.|||Membrane http://togogenome.org/gene/50390:LOC114325296 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1C8 ^@ Similarity|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Homodimer. http://togogenome.org/gene/50390:LOC114336400 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6C1|||http://purl.uniprot.org/uniprot/A0A6P7GCH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERGIC family.|||Endoplasmic reticulum-Golgi intermediate compartment membrane http://togogenome.org/gene/50390:LOC114344759 ^@ http://purl.uniprot.org/uniprot/A0A6P7GNB6 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/50390:LOC114331837 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMJ6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|||Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).|||Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.|||Membrane http://togogenome.org/gene/50390:LOC114327111 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9K0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit K family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/50390:LOC114333619 ^@ http://purl.uniprot.org/uniprot/A0A6P7G444 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114331575 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114344084 ^@ http://purl.uniprot.org/uniprot/A0A6P7H400 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/50390:LOC114332643 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0U7 ^@ Similarity ^@ In the C-terminal section; belongs to the OMP decarboxylase family.|||In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/50390:LOC114324182 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXM3 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114335836 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP23/FCF1 family. FCF1 subfamily.|||nucleolus http://togogenome.org/gene/50390:LOC114328362 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBM3|||http://purl.uniprot.org/uniprot/A0A6P7FDU5|||http://purl.uniprot.org/uniprot/A0A6P7FIF8|||http://purl.uniprot.org/uniprot/A0A6P7FIY3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. http://togogenome.org/gene/50390:LOC114338440 ^@ http://purl.uniprot.org/uniprot/A0A6P7GM45 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/50390:LOC114324297 ^@ http://purl.uniprot.org/uniprot/A0A6P7EY27 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/50390:LOC114328110 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MICOS complex subunit Mic10 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114332953 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0E9|||http://purl.uniprot.org/uniprot/A0A6P7G1P6 ^@ Similarity ^@ Belongs to the PTEN phosphatase protein family. http://togogenome.org/gene/50390:LOC114333485 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3M9 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/50390:LOC114325647 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3Y2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/50390:LOC114345953 ^@ http://purl.uniprot.org/uniprot/A0A6P7H4F6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/50390:LOC114324193 ^@ http://purl.uniprot.org/uniprot/A0A6P7EX94|||http://purl.uniprot.org/uniprot/A0A6P7EXQ0|||http://purl.uniprot.org/uniprot/A0A6P7EYU0|||http://purl.uniprot.org/uniprot/A0A6P7F1F9|||http://purl.uniprot.org/uniprot/A0A6P7F2L4 ^@ Similarity ^@ In the C-terminal section; belongs to the trehalose phosphatase family.|||In the N-terminal section; belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/50390:LOC114335308 ^@ http://purl.uniprot.org/uniprot/A0A6P7G921 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114325153 ^@ http://purl.uniprot.org/uniprot/A0A6P7F227 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DONSON family.|||Nucleus http://togogenome.org/gene/50390:LOC114338629 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7D6|||http://purl.uniprot.org/uniprot/A0A6P7GFW3|||http://purl.uniprot.org/uniprot/A0A6P7GIK3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114328527 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJ10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114332540 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPM3 ^@ Similarity ^@ Belongs to the glycosyltransferase 32 family. http://togogenome.org/gene/50390:LOC114325324 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5X4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/50390:LOC114327877 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/50390:LOC114326387 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAC6 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/50390:LOC114329623 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEZ3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114326330 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAF0 ^@ Similarity ^@ Belongs to the WD repeat ATG16 family. http://togogenome.org/gene/50390:LOC114325577 ^@ http://purl.uniprot.org/uniprot/A0A6P7F293|||http://purl.uniprot.org/uniprot/A0A6P7F6Y8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114329490 ^@ http://purl.uniprot.org/uniprot/A0A6P7FF66 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family. http://togogenome.org/gene/50390:LOC114329668 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNW9 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/50390:LOC114327978 ^@ http://purl.uniprot.org/uniprot/A0A6P7FH96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114331347 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKY7 ^@ Similarity ^@ Belongs to the zygin family. http://togogenome.org/gene/50390:LOC114327533 ^@ http://purl.uniprot.org/uniprot/A0A6P7F881 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/50390:LOC114335357 ^@ http://purl.uniprot.org/uniprot/A0A6P7FY29 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/50390:LOC114325205 ^@ http://purl.uniprot.org/uniprot/A0A6P7F115 ^@ Function|||Similarity ^@ Belongs to the calponin family.|||Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. http://togogenome.org/gene/50390:LOC114325884 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8P0 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/50390:LOC114341277 ^@ http://purl.uniprot.org/uniprot/A0A6P7GF36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/50390:LOC114336355 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114335745 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ41 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFS4 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114325448 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3A0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/50390:LOC114324239 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1N1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the insulin family.|||Heterodimer of a B chain and an A chain linked by two disulfide bonds.|||Secreted http://togogenome.org/gene/50390:LOC114328064 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCT7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/50390:LOC126878435 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6C4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIG1 family.|||Membrane http://togogenome.org/gene/50390:LOC114338102 ^@ http://purl.uniprot.org/uniprot/A0A6P7G620 ^@ Function|||Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.|||Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. http://togogenome.org/gene/50390:LOC114328828 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFB4 ^@ Function|||Similarity|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB4 subunit family.|||Complex I is composed of 45 different subunits. http://togogenome.org/gene/50390:LOC114328597 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCD6|||http://purl.uniprot.org/uniprot/A0A6P7FEN0|||http://purl.uniprot.org/uniprot/A0A6P7FJZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114332993 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.|||Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.|||Homotetramer. http://togogenome.org/gene/50390:LOC114327979 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ARL6IP4 family.|||Nucleus speckle|||nucleolus http://togogenome.org/gene/50390:LOC114327436 ^@ http://purl.uniprot.org/uniprot/A0A6P7FET3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114332557 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0I6 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/50390:LOC114345421 ^@ http://purl.uniprot.org/uniprot/A0A6P7GRA1|||http://purl.uniprot.org/uniprot/A0A6P7GRB2|||http://purl.uniprot.org/uniprot/A0A6P7H0S7|||http://purl.uniprot.org/uniprot/A0A6P7H2Z8|||http://purl.uniprot.org/uniprot/A0A6P7H812 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nucleus http://togogenome.org/gene/50390:LOC114329084 ^@ http://purl.uniprot.org/uniprot/A0A6P7FG59 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase F subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex (By similarity). The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H (By similarity). The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits VhaAC45 and ATP6AP2. http://togogenome.org/gene/50390:LOC114328231 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAE2|||http://purl.uniprot.org/uniprot/A0A6P7FB70|||http://purl.uniprot.org/uniprot/A0A6P7FDC5|||http://purl.uniprot.org/uniprot/A0A6P7FIB6 ^@ Similarity ^@ Belongs to the aldolase class II family. Adducin subfamily. http://togogenome.org/gene/50390:LOC114336361 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0Y6 ^@ Similarity ^@ Belongs to the HARBI1 family. http://togogenome.org/gene/50390:LOC114343861 ^@ http://purl.uniprot.org/uniprot/A0A6P7GKR3|||http://purl.uniprot.org/uniprot/A0A6P7GYJ2|||http://purl.uniprot.org/uniprot/A0A6P7GYK8 ^@ Similarity ^@ Belongs to the MAGUK family. http://togogenome.org/gene/50390:LOC114326671 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBI5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114328457 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIS3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114328232 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHY9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SNUT3 family.|||May play a role in mRNA splicing.|||Nucleus|||Part of a tri-snRNP complex. http://togogenome.org/gene/50390:LOC114349392 ^@ http://purl.uniprot.org/uniprot/A0A6P7H1Z8 ^@ Similarity ^@ Belongs to the scoloptoxin-05 family. http://togogenome.org/gene/50390:LOC114330524 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKZ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lipase maturation factor family.|||Endoplasmic reticulum membrane|||Involved in the maturation of specific proteins in the endoplasmic reticulum.|||Membrane http://togogenome.org/gene/50390:LOC114330621 ^@ http://purl.uniprot.org/uniprot/A0A6P7FI98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114331544 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQA1 ^@ Similarity ^@ Belongs to the TCP11 family. http://togogenome.org/gene/50390:LOC114336306 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0T4|||http://purl.uniprot.org/uniprot/A0A6P7G630 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/50390:LOC114343398 ^@ http://purl.uniprot.org/uniprot/A0A6P7H1R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KIF-binding protein family.|||cytoskeleton http://togogenome.org/gene/50390:LOC114332038 ^@ http://purl.uniprot.org/uniprot/A0A6P7FN35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/50390:LOC114326344 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAH9 ^@ Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/50390:LOC114326801 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6D1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS11 family. http://togogenome.org/gene/50390:LOC114335744 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAI5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/50390:LOC114333390 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I LYR family. SDHAF3 subfamily.|||Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.|||Mitochondrion matrix|||Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1. http://togogenome.org/gene/50390:LOC114332259 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/50390:LOC114335732 ^@ http://purl.uniprot.org/uniprot/A0A6P7G477 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG4/ERG24 family.|||Membrane http://togogenome.org/gene/50390:LOC114336871 ^@ http://purl.uniprot.org/uniprot/A0A6P7GDP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 20 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/50390:LOC114324621 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZ69|||http://purl.uniprot.org/uniprot/A0A6P7F469 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114328483 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIU6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/50390:LOC114327149 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OST3/OST6 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114337354 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3L4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114330498 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHQ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DSS1/SEM1 family.|||Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.|||Nucleus http://togogenome.org/gene/50390:LOC114336139 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0D2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114333736 ^@ http://purl.uniprot.org/uniprot/A0A6P7FT87|||http://purl.uniprot.org/uniprot/A0A6P7G4R5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the dihydropyrimidine dehydrogenase family.|||Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.|||Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. http://togogenome.org/gene/50390:LOC114333341 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRL8|||http://purl.uniprot.org/uniprot/A0A6P7FRU7|||http://purl.uniprot.org/uniprot/A0A6P7FW42|||http://purl.uniprot.org/uniprot/A0A6P7G1S5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sestrin family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114330829 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMC8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Nudix hydrolase family. CPSF5 subfamily.|||Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.|||Cytoplasm|||Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.|||Nucleus http://togogenome.org/gene/50390:LOC114328161 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin conjugation factor E4 family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114329404 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMS3 ^@ Similarity ^@ Belongs to the acetyltransferase family. ARD1 subfamily. http://togogenome.org/gene/50390:LOC114334059 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYG8 ^@ Similarity|||Subunit ^@ Belongs to the casein kinase 2 subunit beta family.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/50390:LOC114334447 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUZ9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114330258 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114326020 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3Q1 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/50390:LOC114337868 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5F8|||http://purl.uniprot.org/uniprot/A0A6P7GGP1 ^@ Similarity ^@ Belongs to the PAR3 family. http://togogenome.org/gene/50390:LOC114328551 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJ49|||http://purl.uniprot.org/uniprot/A0A6P7FJQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114325255 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114340243 ^@ http://purl.uniprot.org/uniprot/A0A6P7GBS1 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/50390:LOC114324908 ^@ http://purl.uniprot.org/uniprot/A0A6P7F587 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/50390:LOC114329938 ^@ http://purl.uniprot.org/uniprot/A0A6P7FG42|||http://purl.uniprot.org/uniprot/A0A6P7FPZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the kinesin light chain family.|||Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.|||Oligomeric complex composed of two heavy chains and two light chains.|||cytoskeleton http://togogenome.org/gene/50390:LOC114335230 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9R7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit.|||Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. http://togogenome.org/gene/50390:LOC114331929 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I NDUFA13 subunit family.|||Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114329807 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFM3|||http://purl.uniprot.org/uniprot/A0A6P7FG66|||http://purl.uniprot.org/uniprot/A0A6P7FIP3|||http://purl.uniprot.org/uniprot/A0A6P7FPC9|||http://purl.uniprot.org/uniprot/A0A6P7FPD2|||http://purl.uniprot.org/uniprot/A0A6P7FPG6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114342276 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/50390:LOC114331357 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114329380 ^@ http://purl.uniprot.org/uniprot/A0A6P7FET9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114339306 ^@ http://purl.uniprot.org/uniprot/A0A6P7GPQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC62 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114331378 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUZ5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114330878 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STT3 family.|||Membrane http://togogenome.org/gene/50390:LOC114327311 ^@ http://purl.uniprot.org/uniprot/A0A6P7FA78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114330501 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKW9 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/50390:LOC114326907 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6P6|||http://purl.uniprot.org/uniprot/A0A6P7FCN8 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. http://togogenome.org/gene/50390:LOC114332686 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPS5 ^@ Similarity ^@ Belongs to the ABI family. http://togogenome.org/gene/50390:LOC114333147 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/50390:LOC114332621 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells. In non-neuronal cells wls directs wg secretion. The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26). In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exosome-like vesicles. Postsynaptic wls is required for the trafficking of fz2 through the fz2-interacting protein Grip.|||Belongs to the wntless family.|||Endoplasmic reticulum membrane|||Endosome membrane|||Golgi apparatus membrane|||Interacts with wg; in the Golgi. Interacts with Vps35, a component of the retromer complex; wls stability is regulated by Vps35.|||Membrane|||Postsynaptic cell membrane|||Presynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/50390:LOC114332566 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0J2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114324742 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4I6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114325143 ^@ http://purl.uniprot.org/uniprot/A0A6P7F215|||http://purl.uniprot.org/uniprot/A0A6P7F564 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114328036 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHK0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/50390:LOC114334047 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYE9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SYS1 family.|||Golgi apparatus membrane|||Involved in protein trafficking.|||Membrane http://togogenome.org/gene/50390:LOC114325282 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1A2 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/50390:LOC114324208 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYW9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114335823 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZA2|||http://purl.uniprot.org/uniprot/A0A6P7GAP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EROs family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/50390:LOC114334860 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7E4 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/50390:LOC114329705 ^@ http://purl.uniprot.org/uniprot/A0A6P7FF91 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. http://togogenome.org/gene/50390:LOC114327113 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7E4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/50390:LOC114335491 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3D9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.|||Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.|||nucleolus http://togogenome.org/gene/50390:LOC114335867 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCC8 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/50390:LOC114326560 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB31|||http://purl.uniprot.org/uniprot/Q70EX2 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114339834 ^@ http://purl.uniprot.org/uniprot/A0A6P7GM74 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RMI1 family.|||Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.|||Nucleus http://togogenome.org/gene/50390:LOC114337531 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAE3|||http://purl.uniprot.org/uniprot/A0A6P7GJ54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.|||Cell membrane http://togogenome.org/gene/50390:LOC114331132 ^@ http://purl.uniprot.org/uniprot/A0A6P7FK89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm http://togogenome.org/gene/50390:LOC114333186 ^@ http://purl.uniprot.org/uniprot/A0A6P7FR67 ^@ Function|||Similarity|||Subunit ^@ Belongs to the proteasome subunit S2 family.|||Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.|||Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).|||Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. http://togogenome.org/gene/50390:LOC114330257 ^@ http://purl.uniprot.org/uniprot/A0A6P7FK33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114335190 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2E1|||http://purl.uniprot.org/uniprot/A0A6P7G8L7 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. http://togogenome.org/gene/50390:LOC114327820 ^@ http://purl.uniprot.org/uniprot/A0A6P7F938 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat COPB2 family.|||COPI-coated vesicle membrane|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/50390:LOC114334076 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYJ2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114332013 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRV4 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/50390:LOC114324174 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nudC family.|||Midbody|||spindle http://togogenome.org/gene/50390:LOC114349455 ^@ http://purl.uniprot.org/uniprot/A0A6P7H0X3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Nucleus http://togogenome.org/gene/50390:LOC114324883 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZZ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.|||Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/50390:LOC114334056 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4E8 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/50390:LOC114329797 ^@ http://purl.uniprot.org/uniprot/A0A6P7FG45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-6 family.|||Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.|||Cytoplasm|||Monomer. Associates with the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/50390:LOC114346721 ^@ http://purl.uniprot.org/uniprot/A0A6P7H459 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/50390:LOC114324935 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1B0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIF beta subunit family.|||Nucleus|||TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. http://togogenome.org/gene/50390:LOC114333232 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVV0 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114331259 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKA8|||http://purl.uniprot.org/uniprot/A0A6P7FKN4 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/50390:LOC114335680 ^@ http://purl.uniprot.org/uniprot/A0A6P7GBN9 ^@ Similarity ^@ Belongs to the FHIP family. http://togogenome.org/gene/50390:LOC114332702 ^@ http://purl.uniprot.org/uniprot/A0A6P7G123 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114343279 ^@ http://purl.uniprot.org/uniprot/A0A6P7GIZ5 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/50390:LOC114327870 ^@ http://purl.uniprot.org/uniprot/A0A6P7F984 ^@ Similarity ^@ Belongs to the selenium-binding protein family. http://togogenome.org/gene/50390:LOC114334545 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVM6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114329378 ^@ http://purl.uniprot.org/uniprot/A0A6P7FH56 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/50390:LOC114327994 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCH2 ^@ Similarity ^@ Belongs to the CWF19 family. http://togogenome.org/gene/50390:LOC114327302 ^@ http://purl.uniprot.org/uniprot/A0A6P7FE94|||http://purl.uniprot.org/uniprot/A0A6P7FED8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/50390:LOC114341162 ^@ http://purl.uniprot.org/uniprot/A0A6P7GE20 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||Transcription repressor. http://togogenome.org/gene/50390:LOC114325948 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2M9 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/50390:LOC114339097 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8U2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114324144 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 15 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/50390:LOC114325085 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0M3|||http://purl.uniprot.org/uniprot/A0A6P7F1R5 ^@ Similarity ^@ Belongs to the RAPGEF2 family. http://togogenome.org/gene/50390:LOC114331672 ^@ http://purl.uniprot.org/uniprot/A0A6P7FW08 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/50390:LOC114333506 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWK8 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/50390:LOC114333249 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRL1|||http://purl.uniprot.org/uniprot/A0A6P7G1J7 ^@ Similarity ^@ Belongs to the nucleoplasmin family. http://togogenome.org/gene/50390:LOC114328863 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFF0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS37 family.|||Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.|||Late endosome membrane http://togogenome.org/gene/50390:LOC114332914 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUP1 ^@ Similarity ^@ Belongs to the GET4 family. http://togogenome.org/gene/50390:LOC114328235 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIC0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114326955 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6X3 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/50390:LOC114326335 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4U6|||http://purl.uniprot.org/uniprot/A0A6P7F6K2 ^@ Function ^@ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. http://togogenome.org/gene/50390:LOC114341931 ^@ http://purl.uniprot.org/uniprot/A0A6P7GR56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCDC124 family.|||Midbody http://togogenome.org/gene/50390:LOC114340847 ^@ http://purl.uniprot.org/uniprot/A0A6P7GDB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase d subunit family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114338956 ^@ http://purl.uniprot.org/uniprot/A0A6P7GNL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Deltex family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114336343 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0Z9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RuvB family.|||Nucleus|||Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. http://togogenome.org/gene/50390:LOC114326174 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eS21 family.|||Endoplasmic reticulum|||Rough endoplasmic reticulum|||cytosol http://togogenome.org/gene/50390:LOC114324460 ^@ http://purl.uniprot.org/uniprot/A0A6P7EY46 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/50390:LOC114325519 ^@ http://purl.uniprot.org/uniprot/A0A6P7F228 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114343399 ^@ http://purl.uniprot.org/uniprot/A0A6P7GVH2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/50390:LOC114340801 ^@ http://purl.uniprot.org/uniprot/A0A6P7GQ97 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Monomer. http://togogenome.org/gene/50390:LOC114337398 ^@ http://purl.uniprot.org/uniprot/A0A6P7GF46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/50390:LOC114349332 ^@ http://purl.uniprot.org/uniprot/A0A6P7H9Z2|||http://purl.uniprot.org/uniprot/A0A6P7HCX9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114327141 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6R7 ^@ Similarity ^@ Belongs to the pym family. http://togogenome.org/gene/50390:LOC114341404 ^@ http://purl.uniprot.org/uniprot/A0A6P7GPN0|||http://purl.uniprot.org/uniprot/A0A6P7GRU3|||http://purl.uniprot.org/uniprot/A0A6P7GW00 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114335163 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2A3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS19 family. http://togogenome.org/gene/50390:LOC114326908 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8Q0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114334649 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COPG family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/50390:LOC114334799 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVZ1|||http://purl.uniprot.org/uniprot/A0A6P7G0W1 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/50390:LOC114331041 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJZ9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS10 family. http://togogenome.org/gene/50390:LOC114337969 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5S1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114329386 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEU9|||http://purl.uniprot.org/uniprot/A0A6P7FMK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRI3 family.|||Membrane|||perinuclear region http://togogenome.org/gene/50390:LOC114330337 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHB5|||http://purl.uniprot.org/uniprot/A0A6P7FRG3 ^@ Similarity ^@ Belongs to the SMP-30/CGR1 family. http://togogenome.org/gene/50390:LOC114327144 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDJ6 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/50390:LOC114327799 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGE7 ^@ Similarity|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Homodimer. http://togogenome.org/gene/50390:LOC114333308 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/50390:LOC114327974 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCE9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/50390:LOC114324903 ^@ http://purl.uniprot.org/uniprot/A0A6P7F581 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL15 family. http://togogenome.org/gene/50390:LOC114325120 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1Y7 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. http://togogenome.org/gene/50390:LOC114335354 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2Z6 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114337264 ^@ http://purl.uniprot.org/uniprot/A0A6P7GI65 ^@ Function|||Similarity ^@ Belongs to the WD repeat EMAP family.|||May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic. http://togogenome.org/gene/50390:LOC114328962 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLA9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114326085 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5H3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114327488 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAU9 ^@ Similarity ^@ Belongs to the eukaryotic-type N-acetylglucosamine kinase family. http://togogenome.org/gene/50390:LOC114329112 ^@ http://purl.uniprot.org/uniprot/A0A6P7FD35 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/50390:LOC114331774 ^@ http://purl.uniprot.org/uniprot/A0A6P7FR26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS26 family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114338583 ^@ http://purl.uniprot.org/uniprot/A0A6P7GMG1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/50390:LOC114342894 ^@ http://purl.uniprot.org/uniprot/A0A6P7H0F8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC41A transporter family.|||Membrane http://togogenome.org/gene/50390:LOC114336351 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCC2 ^@ Similarity ^@ Belongs to the enolase family. http://togogenome.org/gene/50390:LOC114329133 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 28 family.|||Nucleus http://togogenome.org/gene/50390:LOC114336477 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6N1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transcriptional coactivator PC4 family.|||Nucleus http://togogenome.org/gene/50390:LOC114332687 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQ25 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/50390:LOC114345720 ^@ http://purl.uniprot.org/uniprot/A0A6P7H1H0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/50390:LOC114325819 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8G4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114329050 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLK3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SCAR/WAVE family.|||Binds actin and the Arp2/3 complex.|||Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.|||cytoskeleton http://togogenome.org/gene/50390:LOC114330487 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKV4 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/50390:LOC114347531 ^@ http://purl.uniprot.org/uniprot/A0A6P7GWB0|||http://purl.uniprot.org/uniprot/A0A6P7H8L6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.|||Component of a multi-subunit COQ enzyme complex.|||Mitochondrion inner membrane|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/50390:LOC114325663 ^@ http://purl.uniprot.org/uniprot/A0A6P7F401|||http://purl.uniprot.org/uniprot/A0A6P7F7Z9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xanthine dehydrogenase family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Binds 2 [2Fe-2S] clusters.|||Homodimer.|||Peroxisome http://togogenome.org/gene/50390:LOC114326734 ^@ http://purl.uniprot.org/uniprot/A0A6P7F810 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0456 family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114325414 ^@ http://purl.uniprot.org/uniprot/A0A6P7F777 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.|||Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/50390:LOC114331159 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OSTC family.|||Component of the oligosaccharyltransferase (OST) complex.|||Membrane|||Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/50390:LOC114334509 ^@ http://purl.uniprot.org/uniprot/A0A6P7G633|||http://purl.uniprot.org/uniprot/A0A6P7G643 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BBS5 family.|||Membrane|||centriolar satellite|||cilium membrane http://togogenome.org/gene/50390:LOC114327922 ^@ http://purl.uniprot.org/uniprot/A0A6P7FC94 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/50390:LOC114325241 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2E3|||http://purl.uniprot.org/uniprot/A0A6P7F5K2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114328298 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBF6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RAD23 family.|||Cytoplasm|||Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.|||Nucleus http://togogenome.org/gene/50390:LOC114325974 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3I4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114332282 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZB0 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/50390:LOC114330091 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQD0 ^@ Similarity ^@ Belongs to the PHF5 family. http://togogenome.org/gene/50390:LOC114332128 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/50390:LOC114336535 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1A5 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/50390:LOC114330984 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJH6 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4G family. http://togogenome.org/gene/50390:LOC114328265 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAJ4|||http://purl.uniprot.org/uniprot/A0A6P7FBB4|||http://purl.uniprot.org/uniprot/A0A6P7FBB7|||http://purl.uniprot.org/uniprot/A0A6P7FDH8|||http://purl.uniprot.org/uniprot/A0A6P7FI38|||http://purl.uniprot.org/uniprot/A0A6P7FIH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Membrane|||trans-Golgi network membrane http://togogenome.org/gene/50390:LOC114329003 ^@ http://purl.uniprot.org/uniprot/A0A6P7FL42 ^@ Subcellular Location Annotation|||Subunit ^@ Endoplasmic reticulum|||Golgi apparatus|||Homodimer. The monomeric form is inactive while the homodimer is active.|||Lysosome http://togogenome.org/gene/50390:LOC114330460 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyltransferase 2 family.|||Component of the dolichol-phosphate mannose (DPM) synthase complex.|||Endoplasmic reticulum|||Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. http://togogenome.org/gene/50390:LOC114331776 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELP4 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114339268 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9A2 ^@ Function|||Subcellular Location Annotation ^@ Endosome|||Late endosome|||Membrane|||Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. http://togogenome.org/gene/50390:LOC114330882 ^@ http://purl.uniprot.org/uniprot/A0A6P7FT26 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/50390:LOC114327672 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8M4|||http://purl.uniprot.org/uniprot/A0A6P7F9C7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|||Membrane http://togogenome.org/gene/50390:LOC114325513 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1B7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Su(H) family.|||Nucleus http://togogenome.org/gene/50390:LOC114337073 ^@ http://purl.uniprot.org/uniprot/A0A6P7GHC9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SCC4/mau-2 family.|||Required for association of the cohesin complex with chromatin during interphase. Plays a role in sister chromatid cohesion and normal progression through prometaphase.|||nucleoplasm http://togogenome.org/gene/50390:LOC114349513 ^@ http://purl.uniprot.org/uniprot/A0A6P7H145 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Caudal homeobox family.|||Nucleus http://togogenome.org/gene/50390:LOC114325227 ^@ http://purl.uniprot.org/uniprot/A0A6P7F134 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/50390:LOC114324887 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZZ9 ^@ Similarity ^@ Belongs to the MIX23 family. http://togogenome.org/gene/50390:LOC114330058 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGI1|||http://purl.uniprot.org/uniprot/A0A6P7FQ91|||http://purl.uniprot.org/uniprot/A0A6P7FQH8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114336033 ^@ http://purl.uniprot.org/uniprot/A0A6P7GBC5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114327247 ^@ http://purl.uniprot.org/uniprot/A0A6P7F726 ^@ Similarity ^@ Belongs to the Toll-like receptor family. http://togogenome.org/gene/50390:LOC114327601 ^@ http://purl.uniprot.org/uniprot/A0A6P7F940|||http://purl.uniprot.org/uniprot/A0A6P7FFN3 ^@ Similarity ^@ Belongs to the GKAP1 family. http://togogenome.org/gene/50390:LOC114332556 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.|||Belongs to the low molecular weight phosphotyrosine protein phosphatase family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114328034 ^@ http://purl.uniprot.org/uniprot/A0A6P7FH87 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/50390:LOC114337283 ^@ http://purl.uniprot.org/uniprot/A0A6P7GI83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/50390:LOC114347247 ^@ http://purl.uniprot.org/uniprot/A0A6P7GVL8 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114328033 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9P6 ^@ Similarity ^@ Belongs to the prefoldin subunit alpha family. http://togogenome.org/gene/50390:LOC114330172 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQM1|||http://purl.uniprot.org/uniprot/A0A6P7FQX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMC family.|||Membrane http://togogenome.org/gene/50390:LOC114337302 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9H5 ^@ Similarity ^@ Belongs to the EIF1AD family. http://togogenome.org/gene/50390:LOC114332236 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ54 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with the pre-60S ribosomal particle.|||Belongs to the universal ribosomal protein uL10 family.|||Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.|||Cytoplasm|||nucleolus http://togogenome.org/gene/50390:LOC114335311 ^@ http://purl.uniprot.org/uniprot/A0A6P7GA53 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/50390:LOC114328673 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AMY1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114334920 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWG5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||Mitochondrion|||The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/50390:LOC114330383 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHZ6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114332949 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQM7|||http://purl.uniprot.org/uniprot/A0A6P7G1P1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.|||Cytoplasm|||Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity. http://togogenome.org/gene/50390:LOC114327396 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEM5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes small subunit family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. http://togogenome.org/gene/50390:LOC114335895 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZF8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114324202 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXU6|||http://purl.uniprot.org/uniprot/A0A6P7F2Z0 ^@ Similarity ^@ Belongs to the CC2D1 family. http://togogenome.org/gene/50390:LOC114334057 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTV6|||http://purl.uniprot.org/uniprot/A0A6P7FU65|||http://purl.uniprot.org/uniprot/A0A6P7G5R3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CTL (choline transporter-like) family.|||Cell membrane|||Choline transporter.|||Membrane http://togogenome.org/gene/50390:LOC114329666 ^@ http://purl.uniprot.org/uniprot/A0A6P7FF49|||http://purl.uniprot.org/uniprot/A0A6P7FNQ3 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/50390:LOC114341930 ^@ http://purl.uniprot.org/uniprot/A0A6P7GT60 ^@ Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. http://togogenome.org/gene/50390:LOC114348350 ^@ http://purl.uniprot.org/uniprot/A0A6P7HGD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM134/TMEM230 family.|||Early endosome|||Endosome|||Involved in trafficking and recycling of synaptic vesicles.|||Late endosome|||Membrane|||autophagosome|||synaptic vesicle|||trans-Golgi network http://togogenome.org/gene/50390:LOC114324294 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/50390:LOC114326967 ^@ http://purl.uniprot.org/uniprot/A0A6P7FD09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS5 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/50390:LOC114335583 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYQ3 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/50390:LOC114337179 ^@ http://purl.uniprot.org/uniprot/A0A6P7G932|||http://purl.uniprot.org/uniprot/A0A6P7GEK4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat PRP19 family.|||Homotetramer.|||Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.|||nucleoplasm http://togogenome.org/gene/50390:LOC114334968 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8T3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family. Pelota subfamily.|||Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.|||Cytoplasm http://togogenome.org/gene/50390:LOC114335681 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ10 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SCOC family.|||Positive regulator of amino acid starvation-induced autophagy.|||trans-Golgi network http://togogenome.org/gene/50390:LOC114337662 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4L9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase epsilon subunit B family.|||Nucleus http://togogenome.org/gene/50390:LOC114344883 ^@ http://purl.uniprot.org/uniprot/A0A6P7GZD2 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/50390:LOC114336349 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0X3|||http://purl.uniprot.org/uniprot/A0A6P7G664 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114332469 ^@ http://purl.uniprot.org/uniprot/A0A6P7G035 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114325813 ^@ http://purl.uniprot.org/uniprot/A0A6P7F319|||http://purl.uniprot.org/uniprot/A0A6P7F7S0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114336851 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGI8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Belongs to the scoloptoxin-05 family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/50390:LOC114326626 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7M5|||http://purl.uniprot.org/uniprot/A0A6P7FBR5 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114339593 ^@ http://purl.uniprot.org/uniprot/A0A6P7GJC0 ^@ Similarity ^@ Belongs to the UPF0390 family. http://togogenome.org/gene/50390:LOC114327154 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7J3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114330286 ^@ http://purl.uniprot.org/uniprot/A0A6P7FK64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/50390:LOC114335170 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9I3 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/50390:LOC114327293 ^@ http://purl.uniprot.org/uniprot/A0A6P7FE81 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/50390:LOC114326872 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HEXIM family.|||Nucleus http://togogenome.org/gene/50390:LOC114338982 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8D9|||http://purl.uniprot.org/uniprot/A0A6P7GNP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNU66/SART1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114342687 ^@ http://purl.uniprot.org/uniprot/A0A6P7GHI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Ras family.|||Endosome membrane|||Membrane|||Recycling endosome membrane http://togogenome.org/gene/50390:LOC114337606 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAT8 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114325405 ^@ http://purl.uniprot.org/uniprot/A0A6P7F111 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cell membrane|||coated pit http://togogenome.org/gene/50390:LOC114332528 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0E0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/50390:LOC114333004 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQJ8|||http://purl.uniprot.org/uniprot/A0A6P7FV06|||http://purl.uniprot.org/uniprot/A0A6P7FV11 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114333005 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV43|||http://purl.uniprot.org/uniprot/A0A6P7G0X1 ^@ Similarity ^@ Belongs to the WD repeat WDR91 family. http://togogenome.org/gene/50390:LOC114345651 ^@ http://purl.uniprot.org/uniprot/A0A6P7GQT1 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family. http://togogenome.org/gene/50390:LOC114332516 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPL0|||http://purl.uniprot.org/uniprot/A0A6P7FZ66 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/50390:LOC114332090 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114325117 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0Q6 ^@ Cofactor|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/50390:LOC114349441 ^@ http://purl.uniprot.org/uniprot/A0A6P7H276 ^@ Similarity ^@ Belongs to the SH3BGR family. http://togogenome.org/gene/50390:LOC114339157 ^@ http://purl.uniprot.org/uniprot/A0A6P7GP91 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion matrix|||The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/50390:LOC114333163 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVP2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL34 family. http://togogenome.org/gene/50390:LOC114338297 ^@ http://purl.uniprot.org/uniprot/A0A6P7GHQ5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/50390:LOC114325266 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC3 subfamily.|||Nucleus http://togogenome.org/gene/50390:LOC114347039 ^@ http://purl.uniprot.org/uniprot/A0A6P7GV01|||http://purl.uniprot.org/uniprot/A0A6P7GV12|||http://purl.uniprot.org/uniprot/A0A6P7GVQ4|||http://purl.uniprot.org/uniprot/A0A6P7GVR7|||http://purl.uniprot.org/uniprot/A0A6P7GVR8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114330188 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQZ0 ^@ Similarity|||Subunit ^@ Belongs to the insulin family.|||Heterodimer of a B chain and an A chain linked by two disulfide bonds. http://togogenome.org/gene/50390:LOC114327327 ^@ http://purl.uniprot.org/uniprot/A0A6P7FED6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114336456 ^@ http://purl.uniprot.org/uniprot/A0A6P7G187|||http://purl.uniprot.org/uniprot/A0A6P7G6K4|||http://purl.uniprot.org/uniprot/A0A6P7GCN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Endoplasmic reticulum membrane|||May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.|||Membrane|||Microsome membrane http://togogenome.org/gene/50390:LOC114337759 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4X6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NADP-dependent oxidoreductase L4BD family.|||Cytoplasm|||Monomer or homodimer. http://togogenome.org/gene/50390:LOC114326130 ^@ http://purl.uniprot.org/uniprot/A0A6P7F952 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. http://togogenome.org/gene/50390:LOC114329634 ^@ http://purl.uniprot.org/uniprot/A0A6P7FI21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the clarin family.|||Membrane http://togogenome.org/gene/50390:LOC114345922 ^@ http://purl.uniprot.org/uniprot/A0A6P7H9E6 ^@ Similarity ^@ Belongs to the alpha-carbonic anhydrase family. http://togogenome.org/gene/50390:LOC114338374 ^@ http://purl.uniprot.org/uniprot/A0A6P7GHX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114332937 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114331258 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKA0 ^@ Subcellular Location Annotation ^@ cytosol http://togogenome.org/gene/50390:LOC114331214 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNZ3 ^@ Subcellular Location Annotation ^@ Mitochondrion matrix http://togogenome.org/gene/50390:LOC114324813 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0R7 ^@ Similarity ^@ Belongs to the VPS52 family. http://togogenome.org/gene/50390:LOC114332404 ^@ http://purl.uniprot.org/uniprot/A0A6P7FT96 ^@ Similarity ^@ Belongs to the mTERF family. http://togogenome.org/gene/50390:LOC114328987 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCS8 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/50390:LOC114345870 ^@ http://purl.uniprot.org/uniprot/A0A6P7H483|||http://purl.uniprot.org/uniprot/A0A6P7H9A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/50390:LOC114333797 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTF8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/50390:LOC114336194 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NDC1 family.|||Membrane|||Nucleus membrane|||nuclear pore complex http://togogenome.org/gene/50390:LOC114324379 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXU0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. http://togogenome.org/gene/50390:LOC114326421 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAG9 ^@ Similarity ^@ Belongs to the CDC26 family. http://togogenome.org/gene/50390:LOC114327195 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7P7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114332267 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNE5 ^@ Similarity ^@ Belongs to the multicopper oxidase family. http://togogenome.org/gene/50390:LOC114330659 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/IRO homeobox family.|||Nucleus http://togogenome.org/gene/50390:LOC114329648 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNN7 ^@ Similarity ^@ Belongs to the GTR/RAG GTP-binding protein family. http://togogenome.org/gene/50390:LOC114329911 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGG7 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/50390:LOC114336731 ^@ http://purl.uniprot.org/uniprot/A0A6P7GDA4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DPM3 family.|||Component of the dolichol-phosphate mannose (DPM) synthase complex.|||Endoplasmic reticulum membrane|||Membrane|||Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. http://togogenome.org/gene/50390:LOC114347841 ^@ http://purl.uniprot.org/uniprot/A0A6P7GX44 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS4 family. http://togogenome.org/gene/50390:LOC114324196 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2M4 ^@ Similarity ^@ Belongs to the SMP-30/CGR1 family. http://togogenome.org/gene/50390:LOC114332798 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/50390:LOC114327233 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7U0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.|||Membrane http://togogenome.org/gene/50390:LOC114339116 ^@ http://purl.uniprot.org/uniprot/A0A6P7GK11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Membrane http://togogenome.org/gene/50390:LOC114328047 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9R6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/50390:LOC114330500 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the malectin family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114329626 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNL9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/50390:LOC114324618 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZ65 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TIM21 family.|||Component of the TIM23 complex.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114335030 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWS6 ^@ Similarity ^@ Belongs to the acetyltransferase family. GNAT subfamily. http://togogenome.org/gene/50390:LOC114341240 ^@ http://purl.uniprot.org/uniprot/A0A6P7GE76|||http://purl.uniprot.org/uniprot/A0A6P7GVE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat striatin family.|||Membrane http://togogenome.org/gene/50390:LOC114336848 ^@ http://purl.uniprot.org/uniprot/A0A6P7GDM8 ^@ Similarity ^@ Belongs to the peptidase M67A family. http://togogenome.org/gene/50390:LOC114326247 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9S6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CCDC25 family.|||Endomembrane system|||Interacts (via cytoplasmic region) with ILK. http://togogenome.org/gene/50390:LOC114331404 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKU6|||http://purl.uniprot.org/uniprot/A0A6P7FL90|||http://purl.uniprot.org/uniprot/A0A6P7FL95|||http://purl.uniprot.org/uniprot/A0A6P7FPU0 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/50390:LOC114325251 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0G6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.|||Belongs to the dynein light intermediate chain family.|||Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).|||cytoskeleton http://togogenome.org/gene/50390:LOC114326412 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAF2 ^@ Similarity ^@ Belongs to the IPI1/TEX10 family. http://togogenome.org/gene/50390:LOC114324413 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/50390:LOC114325791 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8D0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM256 family.|||Membrane http://togogenome.org/gene/50390:LOC114336446 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6I7|||http://purl.uniprot.org/uniprot/A0A6P7GCM5 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/50390:LOC114327137 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDK9 ^@ Similarity ^@ Belongs to the SUA5 family. http://togogenome.org/gene/50390:LOC114326713 ^@ http://purl.uniprot.org/uniprot/A0A6P7F628|||http://purl.uniprot.org/uniprot/A0A6P7F7Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC12A transporter family.|||Membrane http://togogenome.org/gene/50390:LOC114341620 ^@ http://purl.uniprot.org/uniprot/A0A6P7GWP3 ^@ Similarity ^@ Belongs to the TCF25 family. http://togogenome.org/gene/50390:LOC114331169 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUN4 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/50390:LOC114326642 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBH8 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114338380 ^@ http://purl.uniprot.org/uniprot/A0A6P7GEN4 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/50390:LOC114332478 ^@ http://purl.uniprot.org/uniprot/A0A6P7G061 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sarcoglycan beta/delta/gamma/zeta family.|||Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.|||Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated with the other sarcoglycans.|||cytoskeleton|||sarcolemma http://togogenome.org/gene/50390:LOC114333803 ^@ http://purl.uniprot.org/uniprot/A0A6P7FT59 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114341865 ^@ http://purl.uniprot.org/uniprot/A0A6P7GT21 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114327442 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7V5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP68 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.|||Cytoplasm|||nucleolus http://togogenome.org/gene/50390:LOC114328450 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/50390:LOC114324612 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZ60|||http://purl.uniprot.org/uniprot/A0A6P7F459 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/50390:LOC114340791 ^@ http://purl.uniprot.org/uniprot/A0A6P7GD54|||http://purl.uniprot.org/uniprot/A0A6P7GD73|||http://purl.uniprot.org/uniprot/A0A6P7GN05|||http://purl.uniprot.org/uniprot/A0A6P7GQ85|||http://purl.uniprot.org/uniprot/A0A6P7GU49 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/50390:LOC114325343 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1J7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGX family.|||Endoplasmic reticulum membrane|||Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. http://togogenome.org/gene/50390:LOC114330234 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQT2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/50390:LOC114337214 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3B9|||http://purl.uniprot.org/uniprot/A0A6P7GHZ5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acid sphingomyelinase family.|||Binds 2 Zn(2+) ions per subunit.|||Converts sphingomyelin to ceramide.|||Secreted http://togogenome.org/gene/50390:LOC114329279 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM120 family.|||Membrane http://togogenome.org/gene/50390:LOC114336018 ^@ http://purl.uniprot.org/uniprot/A0A6P7G004 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits. http://togogenome.org/gene/50390:LOC114349416 ^@ http://purl.uniprot.org/uniprot/A0A6P7H0S4|||http://purl.uniprot.org/uniprot/A0A6P7HA92|||http://purl.uniprot.org/uniprot/A0A6P7HD95|||http://purl.uniprot.org/uniprot/A0A6P7HJ01 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114325466 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114331040 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJN5 ^@ Function|||Similarity ^@ Belongs to the APC10 family.|||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. http://togogenome.org/gene/50390:LOC114329635 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SNAPC3/SRD2 family.|||Nucleus|||Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.|||Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. http://togogenome.org/gene/50390:LOC114329719 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFA5 ^@ Cofactor|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily.|||Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/50390:LOC114340311 ^@ http://purl.uniprot.org/uniprot/A0A6P7GLN5 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. http://togogenome.org/gene/50390:LOC114347214 ^@ http://purl.uniprot.org/uniprot/A0A6P7H5D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114330622 ^@ http://purl.uniprot.org/uniprot/A0A6P7FS61 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/50390:LOC114326240 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9R2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114336404 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCH7 ^@ Similarity ^@ Belongs to the chaperonin (HSP60) family. http://togogenome.org/gene/50390:LOC114336850 ^@ http://purl.uniprot.org/uniprot/A0A6P7G258 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.|||Nucleus http://togogenome.org/gene/50390:LOC114328915 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCK4 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/50390:LOC114327851 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC6/cdc18 family.|||Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.|||Nucleus http://togogenome.org/gene/50390:LOC114326083 ^@ http://purl.uniprot.org/uniprot/A0A6P7F359|||http://purl.uniprot.org/uniprot/A0A6P7F3Z4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/50390:LOC114336353 ^@ http://purl.uniprot.org/uniprot/A0A6P7GEH1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114335301 ^@ http://purl.uniprot.org/uniprot/A0A6P7G911 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZCCHC4 family.|||Cytoplasm|||nucleolus http://togogenome.org/gene/50390:LOC114329051 ^@ http://purl.uniprot.org/uniprot/A0A6P7FL94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP14 family.|||nucleolus http://togogenome.org/gene/50390:LOC114334364 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114337742 ^@ http://purl.uniprot.org/uniprot/A0A6P7G510 ^@ Subcellular Location Annotation ^@ Cytoplasmic vesicle|||Vesicle http://togogenome.org/gene/50390:LOC114325915 ^@ http://purl.uniprot.org/uniprot/A0A6P7F862 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/50390:LOC114328160 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHR0|||http://purl.uniprot.org/uniprot/A0A6P7FI30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAM family.|||Membrane http://togogenome.org/gene/50390:LOC114332051 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYE6 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/50390:LOC114345681 ^@ http://purl.uniprot.org/uniprot/A0A6P7GRW8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COQ7 family.|||Binds 2 iron ions per subunit.|||Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.|||Component of a multi-subunit COQ enzyme complex.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114334622 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVH7|||http://purl.uniprot.org/uniprot/A0A6P7FVU3|||http://purl.uniprot.org/uniprot/A0A6P7G0B3 ^@ Similarity ^@ Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. http://togogenome.org/gene/50390:LOC114326848 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8I6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK3 subfamily.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.|||Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.|||Mitochondrion matrix|||Monomer. http://togogenome.org/gene/50390:LOC114331783 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXD5 ^@ Similarity ^@ Belongs to the prefoldin subunit alpha family. http://togogenome.org/gene/50390:LOC114328474 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114324938 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/50390:LOC114329229 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLU9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114336005 ^@ http://purl.uniprot.org/uniprot/A0A6P7GD09 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL37 family.|||Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. http://togogenome.org/gene/50390:LOC114339831 ^@ http://purl.uniprot.org/uniprot/A0A6P7GK42 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114330625 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIA1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114329196 ^@ http://purl.uniprot.org/uniprot/A0A6P7FM16 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114335731 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114336537 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114333588 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSK9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114327015 ^@ http://purl.uniprot.org/uniprot/A0A6P7FD67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. MFSD6 family.|||Membrane http://togogenome.org/gene/50390:LOC114331005 ^@ http://purl.uniprot.org/uniprot/A0A6P7FU67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TM2 family.|||May function as a co-chaperone.|||Membrane http://togogenome.org/gene/50390:LOC114330231 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/50390:LOC114332249 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNT6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114326389 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM198 family.|||Membrane http://togogenome.org/gene/50390:LOC114326309 ^@ http://purl.uniprot.org/uniprot/A0A6P7F418|||http://purl.uniprot.org/uniprot/A0A6P7F6G4|||http://purl.uniprot.org/uniprot/A0A6P7F6G8|||http://purl.uniprot.org/uniprot/A0A6P7F9Z6 ^@ Similarity ^@ Belongs to the formin homology family. Cappuccino subfamily. http://togogenome.org/gene/50390:LOC114327892 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/50390:LOC114330589 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIN9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/50390:LOC114338189 ^@ http://purl.uniprot.org/uniprot/A0A6P7GHF1 ^@ Similarity ^@ Belongs to the DNAJC25 family. http://togogenome.org/gene/50390:LOC114329651 ^@ http://purl.uniprot.org/uniprot/A0A6P7FF32 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/50390:LOC114345891 ^@ http://purl.uniprot.org/uniprot/A0A6P7H497 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/50390:LOC114328120 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAV5|||http://purl.uniprot.org/uniprot/A0A6P7FHK4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114348805 ^@ http://purl.uniprot.org/uniprot/A0A6P7H0H5|||http://purl.uniprot.org/uniprot/A0A6P7H8Z4|||http://purl.uniprot.org/uniprot/A0A6P7H8Z8 ^@ Similarity ^@ Belongs to the liprin family. Liprin-alpha subfamily. http://togogenome.org/gene/50390:LOC114339809 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAV5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Tim44 family.|||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114324286 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXJ9|||http://purl.uniprot.org/uniprot/A0A6P7F2Z9 ^@ Similarity ^@ Belongs to the RBR family. http://togogenome.org/gene/50390:LOC114333354 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRV8|||http://purl.uniprot.org/uniprot/A0A6P7FW54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA mismatch repair MutS family.|||Component of the post-replicative DNA mismatch repair system (MMR).|||Nucleus http://togogenome.org/gene/50390:LOC114336910 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SRP14 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.|||Cytoplasm|||Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. http://togogenome.org/gene/50390:LOC114330339 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHU4 ^@ Similarity ^@ Belongs to the SMP-30/CGR1 family. http://togogenome.org/gene/50390:LOC114325204 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6D3 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/50390:LOC114326521 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB89 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 5A family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114343163 ^@ http://purl.uniprot.org/uniprot/A0A6P7GJF8|||http://purl.uniprot.org/uniprot/A0A6P7GUW4|||http://purl.uniprot.org/uniprot/A0A6P7GUW9 ^@ Similarity ^@ Belongs to the pellino family. http://togogenome.org/gene/50390:LOC114328471 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBY6|||http://purl.uniprot.org/uniprot/A0A6P7FE96|||http://purl.uniprot.org/uniprot/A0A6P7FIT6|||http://purl.uniprot.org/uniprot/A0A6P7FJD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thymosin beta family.|||cytoskeleton http://togogenome.org/gene/50390:LOC114326959 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCZ5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. http://togogenome.org/gene/50390:LOC114349368 ^@ http://purl.uniprot.org/uniprot/A0A6P7HD27 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114338973 ^@ http://purl.uniprot.org/uniprot/A0A6P7GHQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/50390:LOC114333287 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2W1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAB family.|||Nucleus http://togogenome.org/gene/50390:LOC114331110 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJU1 ^@ Similarity ^@ Belongs to the proteasome subunit S9 family. http://togogenome.org/gene/50390:LOC114327507 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFA9 ^@ Similarity ^@ Belongs to the sepiapterin reductase family. http://togogenome.org/gene/50390:LOC114327447 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAQ9|||http://purl.uniprot.org/uniprot/A0A6P7FEU6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114327184 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7P0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Hyccin family.|||Cell membrane|||Membrane|||cytosol http://togogenome.org/gene/50390:LOC114327882 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGP0 ^@ Function|||Similarity ^@ Belongs to the SMG8 family.|||Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. http://togogenome.org/gene/50390:LOC114325281 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0K5 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/50390:LOC114342274 ^@ http://purl.uniprot.org/uniprot/A0A6P7GU10 ^@ Similarity ^@ Belongs to the TIP41 family. http://togogenome.org/gene/50390:LOC114327968 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCE3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAP-alpha family.|||Endoplasmic reticulum membrane|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins. http://togogenome.org/gene/50390:LOC114332080 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXJ9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114331099 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTS8 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/50390:LOC114329570 ^@ http://purl.uniprot.org/uniprot/A0A6P7FES0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/50390:LOC114327682 ^@ http://purl.uniprot.org/uniprot/A0A6P7FG26 ^@ Similarity ^@ Belongs to the PPase class C family. Prune subfamily. http://togogenome.org/gene/50390:LOC114338456 ^@ http://purl.uniprot.org/uniprot/A0A6P7GM60 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/50390:LOC114329360 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEQ8 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/50390:LOC114326101 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5K1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.|||Belongs to the peptidase S16 family.|||Homohexamer or homoheptamer. Organized in a ring with a central cavity.|||Mitochondrion matrix http://togogenome.org/gene/50390:LOC114331339 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKX6 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||basement membrane http://togogenome.org/gene/50390:LOC114335831 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAQ7 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/50390:LOC114324300 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1W5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/50390:LOC114333851 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTJ6|||http://purl.uniprot.org/uniprot/A0A6P7G548 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/50390:LOC114339615 ^@ http://purl.uniprot.org/uniprot/A0A6P7GB32|||http://purl.uniprot.org/uniprot/A0A6P7GMN9|||http://purl.uniprot.org/uniprot/A0A6P7GQX7 ^@ Similarity|||Subunit ^@ Belongs to the protein kinase superfamily.|||Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin. http://togogenome.org/gene/50390:LOC114328686 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/50390:LOC114332353 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYQ0 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/50390:LOC114333877 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecE/SEC61-gamma family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114324642 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4B9 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114332391 ^@ http://purl.uniprot.org/uniprot/A0A6P7FP68|||http://purl.uniprot.org/uniprot/A0A6P7FT69|||http://purl.uniprot.org/uniprot/A0A6P7FYS8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114338423 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6Y9 ^@ Similarity ^@ Belongs to the SMC family. RAD50 subfamily. http://togogenome.org/gene/50390:LOC114331809 ^@ http://purl.uniprot.org/uniprot/A0A6P7FR74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRP17 family.|||nucleolus http://togogenome.org/gene/50390:LOC114330267 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHN3|||http://purl.uniprot.org/uniprot/A0A6P7FR98 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114334106 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUD8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Clp1 family. Clp1 subfamily.|||Nucleus|||Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation. http://togogenome.org/gene/50390:LOC114338387 ^@ http://purl.uniprot.org/uniprot/A0A6P7GLY5 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||Component of the post-replicative DNA mismatch repair system (MMR). http://togogenome.org/gene/50390:LOC114332822 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQ97 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/50390:LOC114330108 ^@ http://purl.uniprot.org/uniprot/A0A6P7FH25 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114326322 ^@ http://purl.uniprot.org/uniprot/A0A6P7F446 ^@ Similarity ^@ Belongs to the complex I NDUFA12 subunit family. http://togogenome.org/gene/50390:LOC114334039 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTT7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the F-actin-capping protein alpha subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit. http://togogenome.org/gene/50390:LOC114330653 ^@ http://purl.uniprot.org/uniprot/A0A6P7FST4 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/50390:LOC114324554 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2U2 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. HMG-CoA synthase family.|||Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. http://togogenome.org/gene/50390:LOC114345024 ^@ http://purl.uniprot.org/uniprot/A0A6P7GPX0 ^@ Function|||Similarity ^@ Belongs to the MOZART1 family.|||Required for gamma-tubulin complex recruitment to the centrosome. http://togogenome.org/gene/50390:LOC114340327 ^@ http://purl.uniprot.org/uniprot/A0A6P7GLP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ECSIT family.|||Cytoplasm|||Mitochondrion|||Nucleus http://togogenome.org/gene/50390:LOC114329115 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLF8 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/50390:LOC114330657 ^@ http://purl.uniprot.org/uniprot/A0A6P7FID3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RAMP4 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/50390:LOC114325447 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the shootin family.|||Perikaryon|||axon|||cytoskeleton|||lamellipodium http://togogenome.org/gene/50390:LOC114327890 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGP9 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/50390:LOC114325286 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0L3 ^@ Similarity ^@ Belongs to the TTC4 family. http://togogenome.org/gene/50390:LOC114332091 ^@ http://purl.uniprot.org/uniprot/A0A6P7FN85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114337282 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3D1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NSE1 family.|||Component of the Smc5-Smc6 complex.|||Nucleus http://togogenome.org/gene/50390:LOC114326319 ^@ http://purl.uniprot.org/uniprot/A0A6P7F440|||http://purl.uniprot.org/uniprot/A0A6P7F4S4|||http://purl.uniprot.org/uniprot/A0A6P7FA16 ^@ Similarity ^@ Belongs to the calcium channel beta subunit family. http://togogenome.org/gene/50390:LOC114334630 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7L0 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114330842 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMF9 ^@ Caution|||Similarity ^@ Belongs to the cytochrome b5 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114337301 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3K8 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/50390:LOC114326191 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5Z8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MND1 family.|||Nucleus|||Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. http://togogenome.org/gene/50390:LOC114334238 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUQ1 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/50390:LOC114329314 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEJ5|||http://purl.uniprot.org/uniprot/A0A6P7FGY2 ^@ Similarity ^@ Belongs to the VPS8 family. http://togogenome.org/gene/50390:LOC114326712 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5E8|||http://purl.uniprot.org/uniprot/A0A6P7F7Y4|||http://purl.uniprot.org/uniprot/A0A6P7FBZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/50390:LOC114333355 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRN2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/50390:LOC114340255 ^@ http://purl.uniprot.org/uniprot/A0A6P7GSI8 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/50390:LOC114330475 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114332206 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSJ1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S26B family.|||Component of the signal peptidase complex.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114340454 ^@ http://purl.uniprot.org/uniprot/A0A6P7GC99|||http://purl.uniprot.org/uniprot/A0A6P7GCF5 ^@ Function|||Similarity ^@ Belongs to the troponin T family.|||Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. http://togogenome.org/gene/50390:LOC114330199 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114325395 ^@ http://purl.uniprot.org/uniprot/A0A6P7F308 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/50390:LOC114327290 ^@ http://purl.uniprot.org/uniprot/A0A6P7F791|||http://purl.uniprot.org/uniprot/A0A6P7F795|||http://purl.uniprot.org/uniprot/A0A6P7F813|||http://purl.uniprot.org/uniprot/A0A6P7F818|||http://purl.uniprot.org/uniprot/A0A6P7FE69|||http://purl.uniprot.org/uniprot/A0A6P7FE76 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/50390:LOC114325580 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6Z4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114327003 ^@ http://purl.uniprot.org/uniprot/A0A6P7FD37 ^@ Similarity ^@ Belongs to the WD repeat PRL1/PRL2 family. http://togogenome.org/gene/50390:LOC114327191 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7P2|||http://purl.uniprot.org/uniprot/A0A6P7F9Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M13 family.|||Cell membrane http://togogenome.org/gene/50390:LOC114324228 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXE5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.|||Cell membrane|||Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114348113 ^@ http://purl.uniprot.org/uniprot/A0A6P7H7J7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114326730 ^@ http://purl.uniprot.org/uniprot/A0A6P7F805 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the deoxyhypusine hydroxylase family.|||Binds 2 Fe(2+) ions per subunit.|||Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. http://togogenome.org/gene/50390:LOC114330642 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIB8 ^@ Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. http://togogenome.org/gene/50390:LOC114327415 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7T3|||http://purl.uniprot.org/uniprot/A0A6P7FEV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/50390:LOC114332575 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZD6 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114331167 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKD5 ^@ Similarity ^@ Belongs to the GTR/RAG GTP-binding protein family. http://togogenome.org/gene/50390:LOC114333632 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSJ3|||http://purl.uniprot.org/uniprot/A0A6P7FX32 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/50390:LOC114325134 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0S1 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Putative Notch ligand involved in the mediation of Notch signaling. http://togogenome.org/gene/50390:LOC114326947 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/50390:LOC114333289 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRG6|||http://purl.uniprot.org/uniprot/A0A6P7G1M8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyadenylate-binding protein type-1 family.|||Binds the poly(A) tail of mRNA.|||Cytoplasm http://togogenome.org/gene/50390:LOC114327878 ^@ http://purl.uniprot.org/uniprot/A0A6P7F992 ^@ Similarity ^@ Belongs to the DDI1 family. http://togogenome.org/gene/50390:LOC114344361 ^@ http://purl.uniprot.org/uniprot/A0A6P7GY17 ^@ Similarity ^@ Belongs to the selenoprotein M/F family. http://togogenome.org/gene/50390:LOC114342412 ^@ http://purl.uniprot.org/uniprot/A0A6P7GSG8 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/50390:LOC114327277 ^@ http://purl.uniprot.org/uniprot/A0A6P7F771 ^@ Similarity ^@ Belongs to the dynein heavy chain family. http://togogenome.org/gene/50390:LOC114335797 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZB9 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/50390:LOC114334623 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0B8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114328973 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLD0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/50390:LOC114327289 ^@ http://purl.uniprot.org/uniprot/A0A6P7F808|||http://purl.uniprot.org/uniprot/A0A6P7FE70 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/50390:LOC114334075 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUA0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114338165 ^@ http://purl.uniprot.org/uniprot/A0A6P7GHC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MRE11/RAD32 family.|||Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.|||Nucleus http://togogenome.org/gene/50390:LOC114335572 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3L9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114335929 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCJ9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114329362 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMG2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/50390:LOC114324833 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3T0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114327485 ^@ http://purl.uniprot.org/uniprot/A0A6P7F807|||http://purl.uniprot.org/uniprot/A0A6P7FF02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/50390:LOC114332958 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGS family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114326365 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4A3|||http://purl.uniprot.org/uniprot/A0A6P7F4Z4|||http://purl.uniprot.org/uniprot/A0A6P7F6P0|||http://purl.uniprot.org/uniprot/A0A6P7F6P4|||http://purl.uniprot.org/uniprot/A0A6P7FA93|||http://purl.uniprot.org/uniprot/A0A6P7FAM0 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/50390:LOC114336199 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5N8|||http://purl.uniprot.org/uniprot/A0A6P7GDV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/50390:LOC114325413 ^@ http://purl.uniprot.org/uniprot/A0A6P7F322|||http://purl.uniprot.org/uniprot/A0A6P7F691 ^@ Similarity ^@ Belongs to the SGT family. http://togogenome.org/gene/50390:LOC114336206 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0C8 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphoglycerate mutase family. http://togogenome.org/gene/50390:LOC114336430 ^@ http://purl.uniprot.org/uniprot/A0A6P7G115|||http://purl.uniprot.org/uniprot/A0A6P7G120|||http://purl.uniprot.org/uniprot/A0A6P7G162 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114335233 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8R4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCRIP family.|||Nucleus|||Stress granule http://togogenome.org/gene/50390:LOC114337027 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2T2 ^@ Similarity ^@ Belongs to the Toll-like receptor family. http://togogenome.org/gene/50390:LOC114324805 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYW0|||http://purl.uniprot.org/uniprot/A0A6P7EYW4|||http://purl.uniprot.org/uniprot/A0A6P7EYW8|||http://purl.uniprot.org/uniprot/A0A6P7EYX2|||http://purl.uniprot.org/uniprot/A0A6P7EZM1|||http://purl.uniprot.org/uniprot/A0A6P7EZN0|||http://purl.uniprot.org/uniprot/A0A6P7F0P7|||http://purl.uniprot.org/uniprot/A0A6P7F0Q5|||http://purl.uniprot.org/uniprot/A0A6P7F0Q8|||http://purl.uniprot.org/uniprot/A0A6P7F3L7|||http://purl.uniprot.org/uniprot/A0A6P7F3M8|||http://purl.uniprot.org/uniprot/A0A6P7F3N6|||http://purl.uniprot.org/uniprot/A0A6P7F4R2|||http://purl.uniprot.org/uniprot/A0A6P7F4R7|||http://purl.uniprot.org/uniprot/A0A6P7F4S2|||http://purl.uniprot.org/uniprot/A0A6P7F4S9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIEZO (TC 1.A.75) family.|||Membrane http://togogenome.org/gene/50390:LOC114329238 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGQ1 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114331211 ^@ http://purl.uniprot.org/uniprot/A0A6P7FK47|||http://purl.uniprot.org/uniprot/A0A6P7FNY7|||http://purl.uniprot.org/uniprot/A0A6P7FU59 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114337535 ^@ http://purl.uniprot.org/uniprot/A0A6P7GJ64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AUP1 family.|||Membrane http://togogenome.org/gene/50390:LOC114329704 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNT8 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/50390:LOC114336359 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFB5 family.|||Component of the 7-subunit TFIIH core complex.|||In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.|||Nucleus http://togogenome.org/gene/50390:LOC114338298 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6K3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase G subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/50390:LOC114326704 ^@ http://purl.uniprot.org/uniprot/A0A6P7FC22 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMCO1 family.|||Calcium-selective channel required to prevent calcium stores from overfilling.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114325707 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1Y4|||http://purl.uniprot.org/uniprot/A0A6P7F7G5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114324439 ^@ http://purl.uniprot.org/uniprot/A0A6P7EY28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114337586 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA1 family.|||Membrane http://togogenome.org/gene/50390:LOC114332461 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPD3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/50390:LOC114334384 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/50390:LOC114326964 ^@ http://purl.uniprot.org/uniprot/A0A6P7F683 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG9 family.|||Membrane|||Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.|||Preautophagosomal structure membrane http://togogenome.org/gene/50390:LOC114324766 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYS9 ^@ Similarity ^@ Belongs to the EMC7 family. http://togogenome.org/gene/50390:LOC114325926 ^@ http://purl.uniprot.org/uniprot/A0A6P7F868 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNAAF3 family.|||Cytoplasm|||Dynein axonemal particle http://togogenome.org/gene/50390:LOC114325775 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4A6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114325264 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2H0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits. http://togogenome.org/gene/50390:LOC114333231 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRJ2 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114326523 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4V7|||http://purl.uniprot.org/uniprot/A0A6P7F5G6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114349454 ^@ http://purl.uniprot.org/uniprot/A0A6P7EX30|||http://purl.uniprot.org/uniprot/A0A6P7HAG5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 15 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/50390:LOC114328947 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCDC85 family.|||adherens junction http://togogenome.org/gene/50390:LOC114331842 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CEP43 family.|||cilium basal body http://togogenome.org/gene/50390:LOC114327314 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7D4|||http://purl.uniprot.org/uniprot/A0A6P7FA83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/50390:LOC114324261 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXG6 ^@ Similarity ^@ Belongs to the copper type II ascorbate-dependent monooxygenase family. http://togogenome.org/gene/50390:LOC114328826 ^@ http://purl.uniprot.org/uniprot/A0A6P7FK79 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114326026 ^@ http://purl.uniprot.org/uniprot/A0A6P7F301|||http://purl.uniprot.org/uniprot/A0A6P7F3R6|||http://purl.uniprot.org/uniprot/A0A6P7F560|||http://purl.uniprot.org/uniprot/A0A6P7F966 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114326558 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5K3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum|||May play a role in vesicular transport from endoplasmic reticulum to Golgi.|||Part of the multisubunit TRAPP (transport protein particle) complex.|||cis-Golgi network http://togogenome.org/gene/50390:LOC114337625 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAW7 ^@ Similarity ^@ Belongs to the NRDE2 family. http://togogenome.org/gene/50390:LOC114334687 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7T2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114325297 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5S9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/50390:LOC114344754 ^@ http://purl.uniprot.org/uniprot/A0A6P7GP45 ^@ Function|||Subunit ^@ Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.|||Self-associates forming complexes of several hundred monomers. http://togogenome.org/gene/50390:LOC114332093 ^@ http://purl.uniprot.org/uniprot/A0A6P7FN91|||http://purl.uniprot.org/uniprot/A0A6P7FYI5 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1 family. CLIP subfamily.|||Secreted|||The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure. http://togogenome.org/gene/50390:LOC114339960 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAS2|||http://purl.uniprot.org/uniprot/A0A6P7GAW5|||http://purl.uniprot.org/uniprot/A0A6P7GMK3 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 2 family.|||Homotetramer.|||Inhibited by L-aspartic acid.|||Plays an important role in the degradation of dermatan and keratan sulfates. http://togogenome.org/gene/50390:LOC114325851 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4I2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/50390:LOC114327800 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9T8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GrpE family.|||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.|||Mitochondrion matrix http://togogenome.org/gene/50390:LOC114339131 ^@ http://purl.uniprot.org/uniprot/A0A6P7GK26 ^@ Function|||Similarity ^@ Belongs to the PET191 family.|||Involved in an early step of the mitochondrial complex IV assembly process. http://togogenome.org/gene/50390:LOC114327993 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9K4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114327511 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8U1 ^@ Similarity ^@ Belongs to the VPS11 family. http://togogenome.org/gene/50390:LOC114325320 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0R4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114327784 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGD0 ^@ Similarity ^@ Belongs to the peptidase C19 family. USP14/UBP6 subfamily. http://togogenome.org/gene/50390:LOC114336781 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Membrane http://togogenome.org/gene/50390:LOC114325582 ^@ http://purl.uniprot.org/uniprot/A0A6P7F296 ^@ Function|||Similarity ^@ Belongs to the ATPase F chain family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. http://togogenome.org/gene/50390:LOC114336137 ^@ http://purl.uniprot.org/uniprot/A0A6P7G053|||http://purl.uniprot.org/uniprot/A0A6P7GDN1 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. METTL16/RlmF family. http://togogenome.org/gene/50390:LOC114333339 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRL4 ^@ Function|||Similarity ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate. http://togogenome.org/gene/50390:LOC114335563 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYE8|||http://purl.uniprot.org/uniprot/A0A6P7G9W8 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114332577 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0K2 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114334494 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV44 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/50390:LOC114333159 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVM7 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily. http://togogenome.org/gene/50390:LOC114332109 ^@ http://purl.uniprot.org/uniprot/A0A6P7FS60 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114342188 ^@ http://purl.uniprot.org/uniprot/A0A6P7GYC4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-binding oxidoreductase/transferase type 4 family.|||Homodimer.|||Peroxisome http://togogenome.org/gene/50390:LOC114331234 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/50390:LOC114328634 ^@ http://purl.uniprot.org/uniprot/A0A6P7FK75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114329592 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114337278 ^@ http://purl.uniprot.org/uniprot/A0A6P7GET7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/50390:LOC114330509 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHR9|||http://purl.uniprot.org/uniprot/A0A6P7FRQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/50390:LOC114334495 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/50390:LOC114334538 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7A3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/50390:LOC114327437 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAP5 ^@ Similarity ^@ Belongs to the CGI121/TPRKB family. http://togogenome.org/gene/50390:LOC114326544 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4X9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.|||Cell membrane|||Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114331878 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/50390:LOC114328674 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKC8 ^@ Similarity ^@ Belongs to the complex I LYR family. http://togogenome.org/gene/50390:LOC114337222 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3D3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/50390:LOC114327143 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the band 7/mec-2 family.|||Membrane http://togogenome.org/gene/50390:LOC114327165 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6T1 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114332266 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSS8 ^@ Similarity ^@ Belongs to the scoloptoxin-05 family. http://togogenome.org/gene/50390:LOC114338983 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8K4|||http://purl.uniprot.org/uniprot/A0A6P7GHR3 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. http://togogenome.org/gene/50390:LOC114329790 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFJ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK6 subfamily.|||Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity.|||Monomer and homodimer.|||Nucleus http://togogenome.org/gene/50390:LOC114345573 ^@ http://purl.uniprot.org/uniprot/A0A6P7H8C0 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/50390:LOC114332568 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPB6|||http://purl.uniprot.org/uniprot/A0A6P7FTR2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114337582 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4D0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ASF1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114326568 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC24 subfamily.|||COPII-coated vesicle membrane|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114343473 ^@ http://purl.uniprot.org/uniprot/A0A6P7H210 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114325330 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0S2|||http://purl.uniprot.org/uniprot/A0A6P7F0S6|||http://purl.uniprot.org/uniprot/A0A6P7F1H0|||http://purl.uniprot.org/uniprot/A0A6P7F2R6|||http://purl.uniprot.org/uniprot/A0A6P7F2S0|||http://purl.uniprot.org/uniprot/A0A6P7F5Y1|||http://purl.uniprot.org/uniprot/A0A6P7F6W2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/50390:LOC114329480 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEF5 ^@ Similarity ^@ Belongs to the peptidase C64 family. http://togogenome.org/gene/50390:LOC114330658 ^@ http://purl.uniprot.org/uniprot/A0A6P7FST9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 29 family.|||Nucleus http://togogenome.org/gene/50390:LOC114333157 ^@ http://purl.uniprot.org/uniprot/A0A6P7G140 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DRC10 family.|||Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.|||flagellum axoneme http://togogenome.org/gene/50390:LOC114325614 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1N0|||http://purl.uniprot.org/uniprot/A0A6P7F728|||http://purl.uniprot.org/uniprot/A0A6P7F7U1 ^@ Domain|||Similarity ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family. http://togogenome.org/gene/50390:LOC114325600 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1L3|||http://purl.uniprot.org/uniprot/A0A6P7F2B3|||http://purl.uniprot.org/uniprot/A0A6P7F3S4|||http://purl.uniprot.org/uniprot/A0A6P7F713 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/50390:LOC114325137 ^@ http://purl.uniprot.org/uniprot/A0A6P7F000 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.|||Belongs to the SNF2/RAD54 helicase family.|||Component of the INO80 chromatin-remodeling complex.|||Nucleus|||The DBINO region is involved in binding to DNA. http://togogenome.org/gene/50390:LOC114328972 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM53 family.|||Membrane|||Nucleus outer membrane http://togogenome.org/gene/50390:LOC114336812 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7Q1|||http://purl.uniprot.org/uniprot/A0A6P7GDI7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114331758 ^@ http://purl.uniprot.org/uniprot/A0A6P7FM94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the asunder family.|||Nucleus|||perinuclear region http://togogenome.org/gene/50390:LOC114325576 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7Q1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/50390:LOC114347291 ^@ http://purl.uniprot.org/uniprot/A0A6P7HDH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM38 family.|||Membrane http://togogenome.org/gene/50390:LOC114327783 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9R3|||http://purl.uniprot.org/uniprot/A0A6P7FBU6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/50390:LOC114336872 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGM4 ^@ Similarity ^@ Belongs to the HMBS family. http://togogenome.org/gene/50390:LOC114337744 ^@ http://purl.uniprot.org/uniprot/A0A6P7GJW2 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/50390:LOC114326699 ^@ http://purl.uniprot.org/uniprot/A0A6P7F610 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/50390:LOC114337780 ^@ http://purl.uniprot.org/uniprot/A0A6P7G568 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Associates with the spliceosome.|||Nucleus|||Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. http://togogenome.org/gene/50390:LOC114331155 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTZ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATG12 family.|||Forms a conjugate with ATG5.|||Ubiquitin-like protein involved in autophagic vesicle formation. http://togogenome.org/gene/50390:LOC114326785 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8A6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NADP-dependent oxidoreductase L4BD family.|||Cytoplasm|||Monomer or homodimer. http://togogenome.org/gene/50390:LOC114336422 ^@ http://purl.uniprot.org/uniprot/A0A6P7G150|||http://purl.uniprot.org/uniprot/A0A6P7G6F6|||http://purl.uniprot.org/uniprot/A0A6P7GCJ7|||http://purl.uniprot.org/uniprot/A0A6P7GES7 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/50390:LOC114338116 ^@ http://purl.uniprot.org/uniprot/A0A6P7GH83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114329734 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFX1 ^@ Similarity ^@ Belongs to the synembryn family. http://togogenome.org/gene/50390:LOC114332187 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114331593 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWJ9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114327636 ^@ http://purl.uniprot.org/uniprot/A0A6P7F973|||http://purl.uniprot.org/uniprot/A0A6P7FBC4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit.|||Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. http://togogenome.org/gene/50390:LOC114325787 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2Z8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Cytoplasm|||Homotrimer.|||Nucleus http://togogenome.org/gene/50390:LOC114325854 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/50390:LOC114333626 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSR3 ^@ Similarity ^@ Belongs to the CDV3 family. http://togogenome.org/gene/50390:LOC114325563 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7N5 ^@ Similarity ^@ Belongs to the SEN54 family. http://togogenome.org/gene/50390:LOC114324652 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYK3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UQCRB/QCR7 family.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114333233 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1H1 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114345611 ^@ http://purl.uniprot.org/uniprot/A0A6P7H3D1|||http://purl.uniprot.org/uniprot/A0A6P7H8H0 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family. http://togogenome.org/gene/50390:LOC114325123 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZY5 ^@ Subcellular Location Annotation|||Subunit ^@ Homodimer.|||Peroxisome http://togogenome.org/gene/50390:LOC114328640 ^@ http://purl.uniprot.org/uniprot/A0A6P7FK80 ^@ Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family. http://togogenome.org/gene/50390:LOC114331163 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKC4|||http://purl.uniprot.org/uniprot/A0A6P7FNT3|||http://purl.uniprot.org/uniprot/A0A6P7FUL8 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/50390:LOC114325238 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0E6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Melanosome|||Membrane|||SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.|||cis-Golgi network membrane http://togogenome.org/gene/50390:LOC114327957 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9G0|||http://purl.uniprot.org/uniprot/A0A6P7FH58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114336853 ^@ http://purl.uniprot.org/uniprot/A0A6P7GDN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114335475 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9L6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat DCAF13/WDSOF1 family.|||nucleolus http://togogenome.org/gene/50390:LOC114330106 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQP1 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/50390:LOC114339188 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8U8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Adaptor protein complex 3 (AP-3) is a heterotetramer.|||Belongs to the adaptor complexes large subunit family.|||Golgi apparatus http://togogenome.org/gene/50390:LOC114333664 ^@ http://purl.uniprot.org/uniprot/A0A6P7FX82 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/50390:LOC114327943 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family. Mth subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114340333 ^@ http://purl.uniprot.org/uniprot/A0A6P7GC08|||http://purl.uniprot.org/uniprot/A0A6P7GC66|||http://purl.uniprot.org/uniprot/A0A6P7GCI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SID1 family.|||Membrane http://togogenome.org/gene/50390:LOC114325291 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5R9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Component of a multi-subunit COQ enzyme complex.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114325093 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1S8 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/50390:LOC114331056 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNF6 ^@ Similarity ^@ Belongs to the ZC3H15/TMA46 family. http://togogenome.org/gene/50390:LOC114333899 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTG2|||http://purl.uniprot.org/uniprot/A0A6P7FTQ7|||http://purl.uniprot.org/uniprot/A0A6P7FY22|||http://purl.uniprot.org/uniprot/A0A6P7G5A0 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/50390:LOC114330834 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTE3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114332985 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUY1|||http://purl.uniprot.org/uniprot/A0A6P7G1S1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/50390:LOC114340705 ^@ http://purl.uniprot.org/uniprot/A0A6P7GMS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPEG family.|||Membrane http://togogenome.org/gene/50390:LOC114326791 ^@ http://purl.uniprot.org/uniprot/A0A6P7FC89 ^@ Function|||Similarity ^@ Belongs to the catalase family.|||Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. http://togogenome.org/gene/50390:LOC114342935 ^@ http://purl.uniprot.org/uniprot/A0A6P7GI31 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10A family.|||Binds 2 Zn(2+) ions per subunit.|||Can bind about 5 Ca(2+) ions per subunit. http://togogenome.org/gene/50390:LOC114336951 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGY2 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. http://togogenome.org/gene/50390:LOC114337537 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAF5 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/50390:LOC114334446 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/50390:LOC114328523 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBB5 ^@ Function|||Similarity ^@ Belongs to the SEC15 family.|||Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. http://togogenome.org/gene/50390:LOC114336756 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1V7|||http://purl.uniprot.org/uniprot/A0A6P7G7I8|||http://purl.uniprot.org/uniprot/A0A6P7GG16 ^@ Similarity ^@ Belongs to the spectrin family. http://togogenome.org/gene/50390:LOC114326278 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAB9 ^@ Subcellular Location Annotation ^@ Membrane|||basement membrane http://togogenome.org/gene/50390:LOC114329217 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGM7|||http://purl.uniprot.org/uniprot/A0A6P7FLS5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 47 family. http://togogenome.org/gene/50390:LOC114325783 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4A9|||http://purl.uniprot.org/uniprot/A0A6P7F7N9 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/50390:LOC114333235 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRJ7 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114341403 ^@ http://purl.uniprot.org/uniprot/A0A6P7GEJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114326944 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCS4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS10 family. http://togogenome.org/gene/50390:LOC114339816 ^@ http://purl.uniprot.org/uniprot/A0A6P7GR79 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/50390:LOC114331669 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWW8 ^@ Function|||Similarity ^@ Belongs to the CDC123 family.|||Required for S phase entry of the cell cycle. http://togogenome.org/gene/50390:LOC114343822 ^@ http://purl.uniprot.org/uniprot/A0A6P7H369 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/50390:LOC114327604 ^@ http://purl.uniprot.org/uniprot/A0A6P7F944|||http://purl.uniprot.org/uniprot/A0A6P7FFP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114326380 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Membrane http://togogenome.org/gene/50390:LOC114347695 ^@ http://purl.uniprot.org/uniprot/A0A6P7GXJ6|||http://purl.uniprot.org/uniprot/A0A6P7GXL7|||http://purl.uniprot.org/uniprot/A0A6P7H970|||http://purl.uniprot.org/uniprot/A0A6P7HEK6|||http://purl.uniprot.org/uniprot/A0A6P7HEN4 ^@ Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family. http://togogenome.org/gene/50390:LOC114325946 ^@ http://purl.uniprot.org/uniprot/A0A6P7F885 ^@ Similarity ^@ Belongs to the UPF0545 family. http://togogenome.org/gene/50390:LOC114338517 ^@ http://purl.uniprot.org/uniprot/A0A6P7G794 ^@ Similarity ^@ Belongs to the OPI10 family. http://togogenome.org/gene/50390:LOC114333214 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.|||Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/50390:LOC114330526 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHU5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.|||Cytoplasm|||S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha. http://togogenome.org/gene/50390:LOC114347497 ^@ http://purl.uniprot.org/uniprot/A0A6P7H625|||http://purl.uniprot.org/uniprot/A0A6P7HE13 ^@ Similarity ^@ Belongs to the MAD1 family. http://togogenome.org/gene/50390:LOC114331356 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL49 family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114327319 ^@ http://purl.uniprot.org/uniprot/A0A6P7FA92 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/50390:LOC114335109 ^@ http://purl.uniprot.org/uniprot/A0A6P7G237 ^@ Similarity ^@ Belongs to the FAM193 family. http://togogenome.org/gene/50390:LOC114334659 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0H2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/50390:LOC114327973 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAB8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/50390:LOC114331770 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLX1|||http://purl.uniprot.org/uniprot/A0A6P7FWC0 ^@ Similarity ^@ Belongs to the ANT/ATPSC lysine N-methyltransferase family. http://togogenome.org/gene/50390:LOC114328258 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAI2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.|||Binds 2 magnesium ions per subunit.|||Nucleus http://togogenome.org/gene/50390:LOC114327155 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9L5 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/50390:LOC114325883 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.|||Nucleus http://togogenome.org/gene/50390:LOC114333439 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/50390:LOC114326849 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCD5 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily. http://togogenome.org/gene/50390:LOC114335455 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAP7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114331043 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RPAP2 family.|||Nucleus|||Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation. http://togogenome.org/gene/50390:LOC114326306 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6F9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114324749 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114329292 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMC3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SDA1 family.|||Required for 60S pre-ribosomal subunits export to the cytoplasm.|||nucleolus http://togogenome.org/gene/50390:LOC114336356 ^@ http://purl.uniprot.org/uniprot/A0A6P7GEH9 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/50390:LOC114324289 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXK6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114325160 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF10 family.|||Nucleus http://togogenome.org/gene/50390:LOC114328127 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAW5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMDT1/EMRE family.|||Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.|||Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114341382 ^@ http://purl.uniprot.org/uniprot/A0A6P7GRS3 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/50390:LOC114324622 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0A7 ^@ Similarity ^@ Belongs to the PITHD1 family. http://togogenome.org/gene/50390:LOC114333461 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ferredoxin--NADP reductase type 1 family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114326185 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9V0 ^@ Similarity ^@ In the N-terminal section; belongs to the MoaB/Mog family. http://togogenome.org/gene/50390:LOC114331341 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUS6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114326104 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5K6|||http://purl.uniprot.org/uniprot/A0A6P7F8X8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/50390:LOC114338227 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6E0|||http://purl.uniprot.org/uniprot/A0A6P7GHJ1 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114327854 ^@ http://purl.uniprot.org/uniprot/A0A6P7F972 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic/archaeal RNase P protein component 2 family.|||Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.|||nucleolus http://togogenome.org/gene/50390:LOC114331117 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTV5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the citrate synthase family.|||Homodimer.|||Mitochondrion matrix http://togogenome.org/gene/50390:LOC114327852 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGK5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/50390:LOC114329795 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFK4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114327156 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6S4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL39 family. http://togogenome.org/gene/50390:LOC114328003 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114325439 ^@ http://purl.uniprot.org/uniprot/A0A6P7F148 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FIS1 family.|||Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.|||Membrane|||Mitochondrion outer membrane|||The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission. http://togogenome.org/gene/50390:LOC114332421 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZV4 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114325500 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7E9 ^@ Function|||Similarity ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. http://togogenome.org/gene/50390:LOC114343912 ^@ http://purl.uniprot.org/uniprot/A0A6P7GKV2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/50390:LOC114336495 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6Q8 ^@ Cofactor|||Similarity ^@ Belongs to the glutamate synthase family.|||Binds 1 [3Fe-4S] cluster. http://togogenome.org/gene/50390:LOC114334293 ^@ http://purl.uniprot.org/uniprot/A0A6P7G599 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-delta family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/50390:LOC114325346 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0U7 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Putative Notch ligand involved in the mediation of Notch signaling. http://togogenome.org/gene/50390:LOC114327593 ^@ http://purl.uniprot.org/uniprot/A0A6P7F933|||http://purl.uniprot.org/uniprot/A0A6P7FB82 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/50390:LOC114326321 ^@ http://purl.uniprot.org/uniprot/A0A6P7FA21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG13 family. Metazoan subfamily.|||Preautophagosomal structure http://togogenome.org/gene/50390:LOC114336235 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0L2|||http://purl.uniprot.org/uniprot/A0A6P7G5R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114343911 ^@ http://purl.uniprot.org/uniprot/A0A6P7GLK6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114328671 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJM0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit alpha family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/50390:LOC114333652 ^@ http://purl.uniprot.org/uniprot/A0A6P7FX58 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/50390:LOC114335669 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYZ7|||http://purl.uniprot.org/uniprot/A0A6P7G407 ^@ Similarity ^@ Belongs to the sorting nexin family. http://togogenome.org/gene/50390:LOC114328495 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB85|||http://purl.uniprot.org/uniprot/A0A6P7FB91|||http://purl.uniprot.org/uniprot/A0A6P7FC17|||http://purl.uniprot.org/uniprot/A0A6P7FEC2|||http://purl.uniprot.org/uniprot/A0A6P7FIW3|||http://purl.uniprot.org/uniprot/A0A6P7FIW8|||http://purl.uniprot.org/uniprot/A0A6P7FJG5|||http://purl.uniprot.org/uniprot/A0A6P7FJG9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114324380 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYE2 ^@ Similarity ^@ Belongs to the CIMIP2 family. http://togogenome.org/gene/50390:LOC114327686 ^@ http://purl.uniprot.org/uniprot/A0A6P7FG31 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114325402 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1R8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 6 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/50390:LOC114330191 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJX9 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/50390:LOC114330232 ^@ http://purl.uniprot.org/uniprot/A0A6P7FK10 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Nucleus http://togogenome.org/gene/50390:LOC114344477 ^@ http://purl.uniprot.org/uniprot/A0A6P7GNA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallophosphoesterase superfamily. MPPE1 family.|||Membrane http://togogenome.org/gene/50390:LOC114324416 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXZ0|||http://purl.uniprot.org/uniprot/A0A6P7F2D3 ^@ Similarity ^@ Belongs to the PACS family. http://togogenome.org/gene/50390:LOC114340143 ^@ http://purl.uniprot.org/uniprot/A0A6P7GBR2 ^@ Function|||Similarity ^@ Belongs to the E(R) family.|||May have a role in the cell cycle. http://togogenome.org/gene/50390:LOC114334360 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6P9 ^@ Similarity ^@ Belongs to the glycosyltransferase 32 family. http://togogenome.org/gene/50390:LOC114335310 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXP8|||http://purl.uniprot.org/uniprot/A0A6P7G2V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FUN14 family.|||Mitochondrion outer membrane http://togogenome.org/gene/50390:LOC114332390 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNQ1|||http://purl.uniprot.org/uniprot/A0A6P7FZR4 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Nucleus http://togogenome.org/gene/50390:LOC114329464 ^@ http://purl.uniprot.org/uniprot/A0A6P7FF38 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114326541 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5I5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.|||Cell membrane|||Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114333022 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV28 ^@ Similarity ^@ Belongs to the peptidase S1 family. CLIP subfamily. http://togogenome.org/gene/50390:LOC114329094 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLQ3 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/50390:LOC114332426 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZV9 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/50390:LOC114342260 ^@ http://purl.uniprot.org/uniprot/A0A6P7GU23 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyadenylate-binding protein type-1 family.|||Binds the poly(A) tail of mRNA.|||Cytoplasm http://togogenome.org/gene/50390:LOC114339413 ^@ http://purl.uniprot.org/uniprot/A0A6P7GKX0 ^@ Similarity ^@ Belongs to the major royal jelly protein family. http://togogenome.org/gene/50390:LOC114333783 ^@ http://purl.uniprot.org/uniprot/A0A6P7FT43 ^@ Similarity ^@ Belongs to the NUP210 family. http://togogenome.org/gene/50390:LOC114324614 ^@ http://purl.uniprot.org/uniprot/A0A6P7F337 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM242 family.|||Membrane http://togogenome.org/gene/50390:LOC114332778 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPW4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/50390:LOC114342854 ^@ http://purl.uniprot.org/uniprot/A0A6P7GI66 ^@ Similarity ^@ Belongs to the multicopper oxidase family. http://togogenome.org/gene/50390:LOC114326402 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAS6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SF3B5 family.|||Component of the spliceosome B complex.|||Nucleus http://togogenome.org/gene/50390:LOC114331784 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMD0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB2 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114332676 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPS0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114332204 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYZ6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/50390:LOC114331405 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP-dependent DNA ligase family.|||Nucleus http://togogenome.org/gene/50390:LOC114339290 ^@ http://purl.uniprot.org/uniprot/A0A6P7GPL9 ^@ Similarity ^@ Belongs to the Iojap/RsfS family. http://togogenome.org/gene/50390:LOC114324627 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZ81|||http://purl.uniprot.org/uniprot/A0A6P7F0B4|||http://purl.uniprot.org/uniprot/A0A6P7F482 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nucleus http://togogenome.org/gene/50390:LOC114333514 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3R1 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/50390:LOC114328180 ^@ http://purl.uniprot.org/uniprot/A0A6P7FI54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/50390:LOC114340503 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntrophin family.|||cytoskeleton http://togogenome.org/gene/50390:LOC114337540 ^@ http://purl.uniprot.org/uniprot/A0A6P7G493|||http://purl.uniprot.org/uniprot/A0A6P7G4F5 ^@ Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family. http://togogenome.org/gene/50390:LOC114337849 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGK1 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/50390:LOC114329203 ^@ http://purl.uniprot.org/uniprot/A0A6P7FE87|||http://purl.uniprot.org/uniprot/A0A6P7FLR1 ^@ Similarity ^@ Belongs to the alpha-actinin family. http://togogenome.org/gene/50390:LOC114325619 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7U6 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/50390:LOC114329021 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLI3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-binding oxidoreductase/transferase type 4 family.|||Homodimer.|||Peroxisome http://togogenome.org/gene/50390:LOC114327057 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9B5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit L family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/50390:LOC114326796 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6C1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynactin subunit 4 family.|||cell cortex|||centrosome|||sarcomere|||stress fiber http://togogenome.org/gene/50390:LOC114335818 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAP4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114328586 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJ99 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL42 family. http://togogenome.org/gene/50390:LOC114326162 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9S0 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/50390:LOC114329355 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDZ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA8 subunit family.|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/50390:LOC114325979 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4Y3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Rab family. http://togogenome.org/gene/50390:LOC114328626 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJU0 ^@ Similarity ^@ Belongs to the phospholipase D family. http://togogenome.org/gene/50390:LOC114326840 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8I2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-delta family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/50390:LOC114326144 ^@ http://purl.uniprot.org/uniprot/A0A6P7F470|||http://purl.uniprot.org/uniprot/A0A6P7F974 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis. http://togogenome.org/gene/50390:LOC114338070 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5Z2 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114331296 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS8 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/50390:LOC114329556 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEQ0 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/50390:LOC114327182 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDR8 ^@ Similarity ^@ Belongs to the dysbindin family. http://togogenome.org/gene/50390:LOC114329187 ^@ http://purl.uniprot.org/uniprot/A0A6P7FE61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/50390:LOC114328964 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFS6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114325133 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZZ5|||http://purl.uniprot.org/uniprot/A0A6P7F613 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/50390:LOC114342524 ^@ http://purl.uniprot.org/uniprot/A0A6P7GZC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 7 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/50390:LOC114327132 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDH5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114333729 ^@ http://purl.uniprot.org/uniprot/A0A6P7FT62 ^@ Similarity ^@ In the C-terminal section; belongs to the peptidase M41 family.|||In the N-terminal section; belongs to the AAA ATPase family. http://togogenome.org/gene/50390:LOC114349356 ^@ http://purl.uniprot.org/uniprot/A0A6P7HA25 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/50390:LOC114325998 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3L1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48A family.|||Binds 1 zinc ion per subunit.|||Endoplasmic reticulum membrane|||Proteolytically removes the C-terminal three residues of farnesylated proteins. http://togogenome.org/gene/50390:LOC114325374 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2Y4 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/50390:LOC114335228 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXN4 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114328905 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDD0 ^@ Similarity ^@ Belongs to the helicase family. SKI2 subfamily. http://togogenome.org/gene/50390:LOC114337755 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4W9|||http://purl.uniprot.org/uniprot/A0A6P7GG99|||http://purl.uniprot.org/uniprot/A0A6P7GJY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the borealin family.|||centromere http://togogenome.org/gene/50390:LOC114324603 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZ49|||http://purl.uniprot.org/uniprot/A0A6P7F449 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the anoctamin family.|||Membrane http://togogenome.org/gene/50390:LOC114328266 ^@ http://purl.uniprot.org/uniprot/A0A6P7FI47|||http://purl.uniprot.org/uniprot/A0A6P7FII2 ^@ Similarity ^@ Belongs to the DSH family. http://togogenome.org/gene/50390:LOC114325446 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1W2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/50390:LOC114328112 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAU6 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/50390:LOC114333920 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5B4 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/50390:LOC114330170 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/50390:LOC114328552 ^@ http://purl.uniprot.org/uniprot/A0A6P7FC82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114327685 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9E7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/50390:LOC114324823 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZQ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ARPC2 family.|||Component of the Arp2/3 complex.|||Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.|||cytoskeleton http://togogenome.org/gene/50390:LOC114333094 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/50390:LOC114343294 ^@ http://purl.uniprot.org/uniprot/A0A6P7GJT5|||http://purl.uniprot.org/uniprot/A0A6P7GWX1 ^@ Similarity ^@ Belongs to the FAX family. http://togogenome.org/gene/50390:LOC114325191 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5F6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.|||Cytoplasm|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||In the N-terminal section; belongs to the flavodoxin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of the anamorsin/DRE2 homolog, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. http://togogenome.org/gene/50390:LOC114329595 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. MFSD6 family.|||Membrane http://togogenome.org/gene/50390:LOC114336358 ^@ http://purl.uniprot.org/uniprot/A0A6P7G673 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NifU family.|||Mitochondrion|||Molecular scaffold for [Fe-S] cluster assembly of mitochondrial iron-sulfur proteins. http://togogenome.org/gene/50390:LOC114331965 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMG4|||http://purl.uniprot.org/uniprot/A0A6P7FY23 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114332916 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUP6|||http://purl.uniprot.org/uniprot/A0A6P7G095 ^@ Function|||Similarity ^@ Belongs to the SHMT family.|||Interconversion of serine and glycine. http://togogenome.org/gene/50390:LOC114327020 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TFP11/STIP family.|||Nucleus http://togogenome.org/gene/50390:LOC114337285 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9G0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114326480 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4R1|||http://purl.uniprot.org/uniprot/A0A6P7F5D0|||http://purl.uniprot.org/uniprot/A0A6P7FAU2|||http://purl.uniprot.org/uniprot/A0A6P7FB42 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MICOS complex subunit Mic60 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114346096 ^@ http://purl.uniprot.org/uniprot/A0A6P7GT54 ^@ Similarity ^@ Belongs to the BCOR family. http://togogenome.org/gene/50390:LOC114335863 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZH6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114324735 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114335181 ^@ http://purl.uniprot.org/uniprot/A0A6P7FX80|||http://purl.uniprot.org/uniprot/A0A6P7G9J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Membrane http://togogenome.org/gene/50390:LOC114330656 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSA2 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/50390:LOC114324841 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZT1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114325609 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3T5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Nucleus http://togogenome.org/gene/50390:LOC114336373 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0V9|||http://purl.uniprot.org/uniprot/A0A6P7GCE4 ^@ Similarity ^@ Belongs to the eukaryotic ATPase epsilon family. http://togogenome.org/gene/50390:LOC114347225 ^@ http://purl.uniprot.org/uniprot/A0A6P7GVI2 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114324808 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0R2 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/50390:LOC114335023 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWR7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/50390:LOC114330795 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJ74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with an ATP-specific beta subunit, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with a GTP-specific beta subunit forms a GDP-forming succinyl-CoA synthetase (G-SCS).|||Mitochondrion|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. http://togogenome.org/gene/50390:LOC114329062 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDV8 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/50390:LOC114330839 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114336384 ^@ http://purl.uniprot.org/uniprot/A0A6P7GCF7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/50390:LOC114349422 ^@ http://purl.uniprot.org/uniprot/A0A6P7H0T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC1 subfamily.|||Nucleus http://togogenome.org/gene/50390:LOC114331843 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWQ9 ^@ Similarity ^@ Belongs to the exportin family. http://togogenome.org/gene/50390:LOC114331265 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. ATF subfamily.|||Nucleus http://togogenome.org/gene/50390:LOC114326529 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114327901 ^@ http://purl.uniprot.org/uniprot/A0A6P7FC71 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/50390:LOC114336157 ^@ http://purl.uniprot.org/uniprot/A0A6P7G075 ^@ Function|||Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.|||Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. http://togogenome.org/gene/50390:LOC114329348 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMD8 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/50390:LOC114339822 ^@ http://purl.uniprot.org/uniprot/A0A6P7GR88 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/50390:LOC114339819 ^@ http://purl.uniprot.org/uniprot/A0A6P7GR83 ^@ Similarity ^@ Belongs to the RBR family. http://togogenome.org/gene/50390:LOC114331275 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUF8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114332107 ^@ http://purl.uniprot.org/uniprot/A0A6P7FS55|||http://purl.uniprot.org/uniprot/A0A6P7FXP0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114337623 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4G9|||http://purl.uniprot.org/uniprot/A0A6P7GFX1|||http://purl.uniprot.org/uniprot/A0A6P7GJG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAN1 family.|||Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.|||Nucleus http://togogenome.org/gene/50390:LOC114336135 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPP small subunits family. Sedlin subfamily.|||perinuclear region http://togogenome.org/gene/50390:LOC114338674 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7I9 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114328994 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDP7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114327027 ^@ http://purl.uniprot.org/uniprot/A0A6P7F985 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114325103 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZW0|||http://purl.uniprot.org/uniprot/A0A6P7F1T7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114333476 ^@ http://purl.uniprot.org/uniprot/A0A6P7G284 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC9 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/50390:LOC114331812 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXJ0 ^@ Similarity ^@ Belongs to the thymidylate kinase family. http://togogenome.org/gene/50390:LOC114326976 ^@ http://purl.uniprot.org/uniprot/A0A6P7FD04 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114346214 ^@ http://purl.uniprot.org/uniprot/A0A6P7H2Q8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.|||Belongs to the NMD3 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114334598 ^@ http://purl.uniprot.org/uniprot/A0A6P7G086 ^@ Similarity ^@ Belongs to the CENP-X/MHF2 family. http://togogenome.org/gene/50390:LOC114333330 ^@ http://purl.uniprot.org/uniprot/A0A6P7G307 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/50390:LOC114339865 ^@ http://purl.uniprot.org/uniprot/A0A6P7GB07 ^@ Subcellular Location Annotation ^@ Membrane|||dendrite http://togogenome.org/gene/50390:LOC114340034 ^@ http://purl.uniprot.org/uniprot/A0A6P7GKU7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114335966 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114333726 ^@ http://purl.uniprot.org/uniprot/A0A6P7G377 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 45 (cellulase K) family. http://togogenome.org/gene/50390:LOC114327318 ^@ http://purl.uniprot.org/uniprot/A0A6P7F865 ^@ Similarity ^@ In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.|||In the N-terminal section; belongs to the ubiquitin family. http://togogenome.org/gene/50390:LOC114349412 ^@ http://purl.uniprot.org/uniprot/A0A6P7HA87 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114332429 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||cis-Golgi network http://togogenome.org/gene/50390:LOC114326871 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114327281 ^@ http://purl.uniprot.org/uniprot/A0A6P7F776 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 2H phosphoesterase superfamily. USB1 family.|||Nucleus|||Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA. http://togogenome.org/gene/50390:LOC114326715 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7Z0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/50390:LOC114325514 ^@ http://purl.uniprot.org/uniprot/A0A6P7F222 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/50390:LOC114328456 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.|||Cleavage furrow|||Midbody|||cilium membrane|||spindle http://togogenome.org/gene/50390:LOC114333047 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0R9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114331232 ^@ http://purl.uniprot.org/uniprot/A0A6P7FK66|||http://purl.uniprot.org/uniprot/A0A6P7FU87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACC family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114324375 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZG4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS25 family. http://togogenome.org/gene/50390:LOC114342915 ^@ http://purl.uniprot.org/uniprot/A0A6P7GU37 ^@ Function|||PTM|||Similarity ^@ Belongs to the eIF-5A family.|||Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. http://togogenome.org/gene/50390:LOC114325391 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1Q2 ^@ Similarity ^@ Belongs to the CWC15 family. http://togogenome.org/gene/50390:LOC114335123 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8D6|||http://purl.uniprot.org/uniprot/A0A6P7G9D0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Late endosome membrane|||Membrane http://togogenome.org/gene/50390:LOC114326962 ^@ http://purl.uniprot.org/uniprot/A0A6P7F913 ^@ Similarity ^@ Belongs to the GORASP family. http://togogenome.org/gene/50390:LOC114328237 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAF4|||http://purl.uniprot.org/uniprot/A0A6P7FDD3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114335364 ^@ http://purl.uniprot.org/uniprot/A0A6P7G301|||http://purl.uniprot.org/uniprot/A0A6P7G981 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/50390:LOC114345199 ^@ http://purl.uniprot.org/uniprot/A0A6P7H068 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/50390:LOC114328133 ^@ http://purl.uniprot.org/uniprot/A0A6P7FA34|||http://purl.uniprot.org/uniprot/A0A6P7FI13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallophosphoesterase superfamily. MPPE1 family.|||Membrane http://togogenome.org/gene/50390:LOC114338127 ^@ http://purl.uniprot.org/uniprot/A0A6P7GL66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 47 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/50390:LOC114328038 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9Q5|||http://purl.uniprot.org/uniprot/A0A6P7FAK1|||http://purl.uniprot.org/uniprot/A0A6P7FCR1|||http://purl.uniprot.org/uniprot/A0A6P7FHK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114324296 ^@ http://purl.uniprot.org/uniprot/A0A6P7F317 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM18 family.|||Membrane http://togogenome.org/gene/50390:LOC114324422 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/50390:LOC114328574 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114335516 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9S0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KRR1 family.|||Monomer. Component of the ribosomal small subunit (SSU) processome.|||Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Binds to RNA. Required for female germline development, cell viability during eye development and for survival of dividing cells and epithelial cells during early wing disk development.|||nucleolus http://togogenome.org/gene/50390:LOC114349233 ^@ http://purl.uniprot.org/uniprot/A0A6P7H9S7|||http://purl.uniprot.org/uniprot/A0A6P7HCR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/50390:LOC114334858 ^@ http://purl.uniprot.org/uniprot/A0A6P7G154|||http://purl.uniprot.org/uniprot/A0A6P7G898 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114342837 ^@ http://purl.uniprot.org/uniprot/A0A6P7GTT8 ^@ Similarity ^@ Belongs to the BCP1 family. http://togogenome.org/gene/50390:LOC114339236 ^@ http://purl.uniprot.org/uniprot/A0A6P7GIB5 ^@ Similarity ^@ Belongs to the NDRG family. http://togogenome.org/gene/50390:LOC114328067 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC2 subfamily.|||Nucleus http://togogenome.org/gene/50390:LOC114333882 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3T5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 30 family. http://togogenome.org/gene/50390:LOC114325769 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8A8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SCM family.|||Nucleus http://togogenome.org/gene/50390:LOC114336354 ^@ http://purl.uniprot.org/uniprot/A0A6P7G668 ^@ Similarity|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/50390:LOC114339418 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9J2|||http://purl.uniprot.org/uniprot/A0A6P7GQ27 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114335425 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAL3 ^@ Similarity ^@ Belongs to the YOS1 family. http://togogenome.org/gene/50390:LOC114328891 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDB4|||http://purl.uniprot.org/uniprot/A0A6P7FL43 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114325917 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2K1 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/50390:LOC114332310 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYK1 ^@ Similarity ^@ Belongs to the SMEK family. http://togogenome.org/gene/50390:LOC114326375 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6U5 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/50390:LOC114329536 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 10 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/50390:LOC114331958 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMV0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114327005 ^@ http://purl.uniprot.org/uniprot/A0A6P7F742 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/50390:LOC114331953 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMF1|||http://purl.uniprot.org/uniprot/A0A6P7FY06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HIBADH-related family. NP60 subfamily.|||Chromosome http://togogenome.org/gene/50390:LOC114331543 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLM7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114332119 ^@ http://purl.uniprot.org/uniprot/A0A6P7FS84 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.|||nucleolus http://togogenome.org/gene/50390:LOC114328573 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEL1 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/50390:LOC114333716 ^@ http://purl.uniprot.org/uniprot/A0A6P7G366|||http://purl.uniprot.org/uniprot/A0A6P7G4I4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114334045 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase VIII family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114336405 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0Y4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114335012 ^@ http://purl.uniprot.org/uniprot/A0A6P7G801 ^@ Cofactor|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/50390:LOC114325307 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5V0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS19 family. http://togogenome.org/gene/50390:LOC114326070 ^@ http://purl.uniprot.org/uniprot/A0A6P7F341 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/50390:LOC114328464 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB51 ^@ Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family.|||Monomer. http://togogenome.org/gene/50390:LOC114336846 ^@ http://purl.uniprot.org/uniprot/A0A6P7G253|||http://purl.uniprot.org/uniprot/A0A6P7G7U0|||http://purl.uniprot.org/uniprot/A0A6P7GGI1 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/50390:LOC114336055 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZW6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/50390:LOC114330384 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIEAP family.|||Cytoplasm|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/50390:LOC114337973 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGY0 ^@ Similarity ^@ Belongs to the EPS8 family. http://togogenome.org/gene/50390:LOC114335686 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYX7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/50390:LOC114331717 ^@ http://purl.uniprot.org/uniprot/A0A6P7FM43 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/50390:LOC114339714 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the carnitine/choline acetyltransferase family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/50390:LOC114335834 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DAD/OST2 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/50390:LOC114338558 ^@ http://purl.uniprot.org/uniprot/A0A6P7GFK9 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/50390:LOC114339285 ^@ http://purl.uniprot.org/uniprot/A0A6P7GPL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/50390:LOC114333832 ^@ http://purl.uniprot.org/uniprot/A0A6P7FT71 ^@ Cofactor|||Similarity ^@ Belongs to the cysteine dioxygenase family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/50390:LOC114330841 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMF0 ^@ Caution|||Similarity ^@ Belongs to the cytochrome b5 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114327389 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAH0 ^@ Subcellular Location Annotation|||Subunit ^@ Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/50390:LOC114337888 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGP3 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/50390:LOC114329326 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGZ1|||http://purl.uniprot.org/uniprot/A0A6P7FMF8 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. http://togogenome.org/gene/50390:LOC114332198 ^@ http://purl.uniprot.org/uniprot/A0A6P7FN68|||http://purl.uniprot.org/uniprot/A0A6P7FYY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/50390:LOC114337175 ^@ http://purl.uniprot.org/uniprot/A0A6P7G381 ^@ Similarity ^@ Belongs to the frataxin family. http://togogenome.org/gene/50390:LOC114336053 ^@ http://purl.uniprot.org/uniprot/A0A6P7G039 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/50390:LOC114336402 ^@ http://purl.uniprot.org/uniprot/A0A6P7G126 ^@ Similarity ^@ Belongs to the SDHAF4 family. http://togogenome.org/gene/50390:LOC114325972 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2P9|||http://purl.uniprot.org/uniprot/A0A6P7F8Y7 ^@ Similarity ^@ Belongs to the CLCR family. http://togogenome.org/gene/50390:LOC114331819 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMH3|||http://purl.uniprot.org/uniprot/A0A6P7FXJ8 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/50390:LOC114329434 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/50390:LOC114337300 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3E9 ^@ Similarity ^@ Belongs to the SPSB family. http://togogenome.org/gene/50390:LOC114331609 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLV2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SCO1/2 family.|||Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.|||Homodimer.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114328069 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHD5 ^@ Similarity ^@ Belongs to the complex I 20 kDa subunit family. http://togogenome.org/gene/50390:LOC114325620 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2H1 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/50390:LOC114342549 ^@ http://purl.uniprot.org/uniprot/A0A6P7GUW1|||http://purl.uniprot.org/uniprot/A0A6P7GZR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/PBX homeobox family.|||Nucleus http://togogenome.org/gene/50390:LOC114328908 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDD6|||http://purl.uniprot.org/uniprot/A0A6P7FFK6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114326702 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7X5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114348679 ^@ http://purl.uniprot.org/uniprot/A0A6P7H8R8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/50390:LOC114326687 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBK2|||http://purl.uniprot.org/uniprot/A0A6P7FBK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/50390:LOC114335087 ^@ http://purl.uniprot.org/uniprot/A0A6P7G205 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Endoplasmic reticulum membrane|||May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.|||Membrane|||Microsome membrane http://togogenome.org/gene/50390:LOC114325837 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7V4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/50390:LOC114335071 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWV2|||http://purl.uniprot.org/uniprot/A0A6P7G1Y7|||http://purl.uniprot.org/uniprot/A0A6P7G863|||http://purl.uniprot.org/uniprot/A0A6P7G960 ^@ Cofactor|||Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/50390:LOC114326928 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114347172 ^@ http://purl.uniprot.org/uniprot/A0A6P7H611 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114335615 ^@ http://purl.uniprot.org/uniprot/A0A6P7GB90 ^@ Similarity ^@ Belongs to the CRK family. http://togogenome.org/gene/50390:LOC114331553 ^@ http://purl.uniprot.org/uniprot/A0A6P7FL69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the flavin monoamine oxidase family.|||Histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3.|||Nucleus http://togogenome.org/gene/50390:LOC114325632 ^@ http://purl.uniprot.org/uniprot/A0A6P7F758 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114338424 ^@ http://purl.uniprot.org/uniprot/A0A6P7GM30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family. BCS1 subfamily.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114340054 ^@ http://purl.uniprot.org/uniprot/A0A6P7GKW5 ^@ Similarity ^@ Belongs to the MON2 family. http://togogenome.org/gene/50390:LOC114327449 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7V9|||http://purl.uniprot.org/uniprot/A0A6P7FAQ3 ^@ Similarity ^@ Belongs to the glutaminyl-peptide cyclotransferase family. http://togogenome.org/gene/50390:LOC114325639 ^@ http://purl.uniprot.org/uniprot/A0A6P7F763 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL23 family. http://togogenome.org/gene/50390:LOC114333480 ^@ http://purl.uniprot.org/uniprot/A0A6P7G290 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/50390:LOC114337048 ^@ http://purl.uniprot.org/uniprot/A0A4D6Q7U5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 45 (cellulase K) family. http://togogenome.org/gene/50390:LOC114342279 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TIM50 family.|||Component of the TIM23 complex.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114336381 ^@ http://purl.uniprot.org/uniprot/A0A6P7G0X0 ^@ Subcellular Location Annotation ^@ Peroxisome http://togogenome.org/gene/50390:LOC114333534 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWN3|||http://purl.uniprot.org/uniprot/A0A6P7G2E3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114325669 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2N1|||http://purl.uniprot.org/uniprot/A0A6P7F410 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF3B1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114330171 ^@ http://purl.uniprot.org/uniprot/A0A6P7FH84 ^@ Function|||Similarity ^@ Belongs to the TCTP family.|||Involved in calcium binding and microtubule stabilization. http://togogenome.org/gene/50390:LOC114331268 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114325628 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2I2 ^@ Subcellular Location Annotation ^@ cytosol http://togogenome.org/gene/50390:LOC114337604 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4M4 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114328337 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAR0|||http://purl.uniprot.org/uniprot/A0A6P7FIC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/IRO homeobox family.|||Nucleus http://togogenome.org/gene/50390:LOC114349040 ^@ http://purl.uniprot.org/uniprot/A0A6P7H9F2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.|||Cytoplasm|||Membrane http://togogenome.org/gene/50390:LOC114329492 ^@ http://purl.uniprot.org/uniprot/A0A6P7FN43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit E family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/50390:LOC114324609 ^@ http://purl.uniprot.org/uniprot/A0A6P7F091 ^@ Cofactor|||Similarity ^@ Belongs to the transglutaminase superfamily. Transglutaminase family.|||Binds 1 Ca(2+) ion per subunit. http://togogenome.org/gene/50390:LOC114328177 ^@ http://purl.uniprot.org/uniprot/A0A6P7FI48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/50390:LOC114333912 ^@ http://purl.uniprot.org/uniprot/A0A6P7FY02 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/50390:LOC114337977 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5S6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/50390:LOC114326336 ^@ http://purl.uniprot.org/uniprot/A0A6P7FA35|||http://purl.uniprot.org/uniprot/A0A6P7FAF9 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/50390:LOC114326603 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7K0 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114333223 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2R4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. http://togogenome.org/gene/50390:LOC114338665 ^@ http://purl.uniprot.org/uniprot/A0A6P7GIQ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||nucleolus http://togogenome.org/gene/50390:LOC114328722 ^@ http://purl.uniprot.org/uniprot/A0A6P7FF26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TUBGCP family.|||microtubule organizing center http://togogenome.org/gene/50390:LOC114331535 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLL6|||http://purl.uniprot.org/uniprot/A0A6P7FWD3 ^@ Function|||Subunit ^@ EF-1 is composed of four subunits: alpha, beta, delta, and gamma.|||Probably plays a role in anchoring the complex to other cellular components. http://togogenome.org/gene/50390:LOC114327939 ^@ http://purl.uniprot.org/uniprot/A0A6P7FA84 ^@ Domain|||Function ^@ E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.|||The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain. http://togogenome.org/gene/50390:LOC114331002 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJI6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114325208 ^@ http://purl.uniprot.org/uniprot/A0A6P7F119|||http://purl.uniprot.org/uniprot/A0A6P7F2C4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/50390:LOC114329550 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHR2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MAP Jupiter family.|||Binds to all microtubule populations.|||Nucleus|||spindle http://togogenome.org/gene/50390:LOC114348478 ^@ http://purl.uniprot.org/uniprot/A0A6P7GYP9|||http://purl.uniprot.org/uniprot/A0A6P7H8E4|||http://purl.uniprot.org/uniprot/A0A6P7H8G2|||http://purl.uniprot.org/uniprot/A0A6P7HGQ1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114339214 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8W2|||http://purl.uniprot.org/uniprot/A0A6P7GPD7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/50390:LOC114333040 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV53|||http://purl.uniprot.org/uniprot/A0A6P7G0Q9 ^@ Similarity ^@ Belongs to the parvin family. http://togogenome.org/gene/50390:LOC114335550 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9V9 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1 family. CLIP subfamily.|||Secreted|||The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure. http://togogenome.org/gene/50390:LOC114335322 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXZ5|||http://purl.uniprot.org/uniprot/A0A6P7G2W2 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/50390:LOC114334080 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUA5|||http://purl.uniprot.org/uniprot/A0A6P7FYJ7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114349372 ^@ http://purl.uniprot.org/uniprot/A0A6P7H1X2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/50390:LOC114332779 ^@ http://purl.uniprot.org/uniprot/A0A6P7G147 ^@ Similarity ^@ Belongs to the HARBI1 family. http://togogenome.org/gene/50390:LOC114334574 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVQ2 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/50390:LOC114335725 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ58|||http://purl.uniprot.org/uniprot/A0A6P7GBV6 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/50390:LOC114334550 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KRTCAP2 family.|||Membrane http://togogenome.org/gene/50390:LOC114344325 ^@ http://purl.uniprot.org/uniprot/A0A6P7H4N7 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/50390:LOC114336735 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1T3|||http://purl.uniprot.org/uniprot/A0A6P7G1Z1|||http://purl.uniprot.org/uniprot/A0A6P7G7F6|||http://purl.uniprot.org/uniprot/A0A6P7GDA9 ^@ Similarity ^@ Belongs to the NRAMP family. http://togogenome.org/gene/50390:LOC114325422 ^@ http://purl.uniprot.org/uniprot/A0A6P7F335 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/50390:LOC114335428 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9F9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat HIR1 family.|||Nucleus|||Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle. http://togogenome.org/gene/50390:LOC114324818 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MAP Jupiter family.|||Binds to all microtubule populations.|||Nucleus|||spindle http://togogenome.org/gene/50390:LOC114335672 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ01 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. CDKAL1 subfamily.|||Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.|||Endoplasmic reticulum membrane http://togogenome.org/gene/50390:LOC114329760 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFG0|||http://purl.uniprot.org/uniprot/A0A6P7FP91 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/50390:LOC114334272 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6H5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/50390:LOC114329482 ^@ http://purl.uniprot.org/uniprot/A0A6P7FN10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIA subunit 1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114328892 ^@ http://purl.uniprot.org/uniprot/A0A6P7FL46 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/50390:LOC114326403 ^@ http://purl.uniprot.org/uniprot/A0A6P7F529 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114340354 ^@ http://purl.uniprot.org/uniprot/A0A6P7GNX7 ^@ Similarity ^@ Belongs to the cAMP-dependent kinase regulatory chain family. http://togogenome.org/gene/50390:LOC114324295 ^@ http://purl.uniprot.org/uniprot/A0A6P7F312 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane magnesium transporter (TC 1.A.67) family.|||Early endosome membrane|||Endosome membrane|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport. http://togogenome.org/gene/50390:LOC114334587 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7G4 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit alpha family. http://togogenome.org/gene/50390:LOC114329814 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFR3 ^@ Similarity ^@ Belongs to the SAP18 family. http://togogenome.org/gene/50390:LOC114333447 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWF1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/50390:LOC114338443 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6Y5|||http://purl.uniprot.org/uniprot/A0A6P7GI67 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114330519 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKY9 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/50390:LOC114332617 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPG9|||http://purl.uniprot.org/uniprot/A0A6P7FPV0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114329270 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDL9 ^@ Similarity ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. http://togogenome.org/gene/50390:LOC114341477 ^@ http://purl.uniprot.org/uniprot/A0A6P7GW74 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.|||Membrane http://togogenome.org/gene/50390:LOC114342252 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGG8|||http://purl.uniprot.org/uniprot/A0A6P7GS11 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.|||Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.|||Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.|||Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.|||Cytoplasm|||centrosome|||spindle|||spindle pole http://togogenome.org/gene/50390:LOC114327136 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6R2|||http://purl.uniprot.org/uniprot/A0A6P7FDI1 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/50390:LOC114329450 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMZ3 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/50390:LOC114332815 ^@ http://purl.uniprot.org/uniprot/A0A6P7G182 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/50390:LOC114329346 ^@ http://purl.uniprot.org/uniprot/A0A6P7FH12|||http://purl.uniprot.org/uniprot/A0A6P7FMI9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114334442 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6Y7 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/50390:LOC114330338 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHT9|||http://purl.uniprot.org/uniprot/A0A6P7FKA9|||http://purl.uniprot.org/uniprot/A0A6P7FR57 ^@ Similarity ^@ Belongs to the SMP-30/CGR1 family. http://togogenome.org/gene/50390:LOC114328969 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCQ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/50390:LOC114332903 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQ89 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/50390:LOC114333436 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3F8 ^@ Similarity ^@ Belongs to the PDE6D/unc-119 family. http://togogenome.org/gene/50390:LOC114327416 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat LST8 family.|||Cytoplasm|||Part of TORC1 complex. Part of the TORC2 complex.|||Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. http://togogenome.org/gene/50390:LOC114334611 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVG3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114324646 ^@ http://purl.uniprot.org/uniprot/A0A6P7F376 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.|||Belongs to the GAMAD family.|||cytoskeleton http://togogenome.org/gene/50390:LOC114326475 ^@ http://purl.uniprot.org/uniprot/A0A6P7F4P8|||http://purl.uniprot.org/uniprot/A0A6P7FB30 ^@ Similarity ^@ Belongs to the FAH family. http://togogenome.org/gene/50390:LOC114341779 ^@ http://purl.uniprot.org/uniprot/A0A6P7GFG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ING family.|||Nucleus http://togogenome.org/gene/50390:LOC114326359 ^@ http://purl.uniprot.org/uniprot/A0A6P7F492|||http://purl.uniprot.org/uniprot/A0A6P7FAK4 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/50390:LOC114327681 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBI2 ^@ Similarity ^@ Belongs to the NUP186/NUP192/NUP205 family. http://togogenome.org/gene/50390:LOC114324468 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYR1|||http://purl.uniprot.org/uniprot/A0A6P7F2L5 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114332372 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYR6 ^@ Similarity ^@ Belongs to the protein disulfide isomerase family. http://togogenome.org/gene/50390:LOC114332117 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYP4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114332133 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA1 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114332207 ^@ http://purl.uniprot.org/uniprot/A0A6P7FY62 ^@ Similarity ^@ Belongs to the PAF1 family. http://togogenome.org/gene/50390:LOC114324405 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXX3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily. http://togogenome.org/gene/50390:LOC114324429 ^@ http://purl.uniprot.org/uniprot/A0A6P7EY09|||http://purl.uniprot.org/uniprot/A0A6P7F2E8 ^@ Similarity ^@ Belongs to the PPP1R15 family. http://togogenome.org/gene/50390:LOC114328571 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/50390:LOC114328622 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBN0|||http://purl.uniprot.org/uniprot/A0A6P7FJE6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114344844 ^@ http://purl.uniprot.org/uniprot/A0A6P7GNK0 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/50390:LOC114335549 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3J5 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1 family. CLIP subfamily.|||Secreted|||The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure. http://togogenome.org/gene/50390:LOC114324251 ^@ http://purl.uniprot.org/uniprot/A0A6P7EXY1 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/50390:LOC114335422 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9F5 ^@ Function|||Similarity ^@ Belongs to the MINDY deubiquitinase family. FAM188 subfamily.|||Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins. http://togogenome.org/gene/50390:LOC114327850 ^@ http://purl.uniprot.org/uniprot/A0A6P7F967 ^@ Similarity ^@ Belongs to the SHQ1 family. http://togogenome.org/gene/50390:LOC114335271 ^@ http://purl.uniprot.org/uniprot/A0A6P7GA12 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/50390:LOC114349474 ^@ http://purl.uniprot.org/uniprot/A0A6P7H2G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114334761 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVX4|||http://purl.uniprot.org/uniprot/A0A6P7FW80 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/50390:LOC114344367 ^@ http://purl.uniprot.org/uniprot/A0A6P7GMY5 ^@ Subcellular Location Annotation ^@ Endomembrane system http://togogenome.org/gene/50390:LOC114330288 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHQ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/50390:LOC114343442 ^@ http://purl.uniprot.org/uniprot/A0A6P7GXC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/50390:LOC114334529 ^@ http://purl.uniprot.org/uniprot/A0A6P7G698 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acid sphingomyelinase family.|||Secreted http://togogenome.org/gene/50390:LOC114325278 ^@ http://purl.uniprot.org/uniprot/A0A6P7F197 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/50390:LOC114347786 ^@ http://purl.uniprot.org/uniprot/A0A6P7H9C4 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/50390:LOC114335775 ^@ http://purl.uniprot.org/uniprot/A0A6P7GAL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114333327 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1R1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RRM NCBP2 family.|||Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires Cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.|||Component of the nuclear cap-binding complex (CBC), a heterodimer composed of Cbp80 and Cbp20 that interacts with m7GpppG-capped RNA.|||Nucleus http://togogenome.org/gene/50390:LOC114330253 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114324789 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3J7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114325450 ^@ http://purl.uniprot.org/uniprot/A0A6P7F157|||http://purl.uniprot.org/uniprot/A0A6P7F161|||http://purl.uniprot.org/uniprot/A0A6P7F3A5|||http://purl.uniprot.org/uniprot/A0A6P7F7C0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/50390:LOC114328730 ^@ http://purl.uniprot.org/uniprot/A0A6P7FC04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the splicing factor SR family.|||Necessary for the splicing of pre-mRNA.|||Nucleus http://togogenome.org/gene/50390:LOC114333282 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRG1 ^@ Subcellular Location Annotation|||Subunit ^@ Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/50390:LOC114337607 ^@ http://purl.uniprot.org/uniprot/A0A6P7GFU7 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114335014 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWQ8 ^@ Similarity ^@ In the N-terminal section; belongs to the SAICAR synthetase family. http://togogenome.org/gene/50390:LOC114326936 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6U3|||http://purl.uniprot.org/uniprot/A0A6P7FCU0 ^@ Subcellular Location Annotation ^@ Nucleus|||cytosol http://togogenome.org/gene/50390:LOC114337738 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4U3 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/50390:LOC114333206 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVT1 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/50390:LOC114339117 ^@ http://purl.uniprot.org/uniprot/A0A6P7GI26 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit D family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.|||mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs. http://togogenome.org/gene/50390:LOC114327912 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9B6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rab GDI family.|||Cytoplasm|||Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. http://togogenome.org/gene/50390:LOC114334691 ^@ http://purl.uniprot.org/uniprot/A0A6P7G6U3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/50390:LOC114324788 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM NELF-E family.|||Chromosome|||Nucleus http://togogenome.org/gene/50390:LOC114326703 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5D9|||http://purl.uniprot.org/uniprot/A0A6P7FBN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRE1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114327407 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7S4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. http://togogenome.org/gene/50390:LOC114341196 ^@ http://purl.uniprot.org/uniprot/A0A6P7GE41 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. http://togogenome.org/gene/50390:LOC114335567 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9X4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/50390:LOC114335561 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3K4 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114327012 ^@ http://purl.uniprot.org/uniprot/A0A6P7F746 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114325502 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1Z4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114327231 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CFAP206 family.|||cilium axoneme http://togogenome.org/gene/50390:LOC114337350 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3L0 ^@ Caution|||Similarity ^@ Belongs to the RAB6IP1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114324846 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZT7 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/50390:LOC114349492 ^@ http://purl.uniprot.org/uniprot/A0A6P7H112 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the clarin family.|||Membrane http://togogenome.org/gene/50390:LOC114349511 ^@ http://purl.uniprot.org/uniprot/A0A6P7H2P7|||http://purl.uniprot.org/uniprot/A0A6P7HAK0|||http://purl.uniprot.org/uniprot/A0A6P7HDM8 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/50390:LOC114332141 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMZ9|||http://purl.uniprot.org/uniprot/A0A6P7FN04|||http://purl.uniprot.org/uniprot/A0A6P7FSB6|||http://purl.uniprot.org/uniprot/A0A6P7FXY0|||http://purl.uniprot.org/uniprot/A0A6P7FYR7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114329359 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HMG-CoA reductase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114328800 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKV2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/50390:LOC114330764 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSN3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114328912 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKL7 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/50390:LOC114326750 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5I6 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/50390:LOC114327653 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBE5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114332349 ^@ http://purl.uniprot.org/uniprot/A0A6P7FP33|||http://purl.uniprot.org/uniprot/A0A6P7FZL3 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/50390:LOC114349330 ^@ http://purl.uniprot.org/uniprot/A0A6P7HIL6 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. http://togogenome.org/gene/50390:LOC114334221 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ18 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114329921 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecY/SEC61-alpha family.|||Membrane http://togogenome.org/gene/50390:LOC114329886 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.|||Cell membrane http://togogenome.org/gene/50390:LOC114340715 ^@ http://purl.uniprot.org/uniprot/A0A6P7GD06 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Interacts with UHRF2/NIRF.|||May be involved in cell cycle regulation.|||Nucleus http://togogenome.org/gene/50390:LOC114326440 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6Z2 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. http://togogenome.org/gene/50390:LOC114327683 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8P1 ^@ Similarity ^@ Belongs to the PPase class C family. Prune subfamily. http://togogenome.org/gene/50390:LOC114331960 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMG0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114333720 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4K0 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/50390:LOC114327965 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MYST (SAS/MOZ) family.|||Nucleus http://togogenome.org/gene/50390:LOC114332244 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNC1 ^@ Similarity ^@ Belongs to the scoloptoxin-05 family. http://togogenome.org/gene/50390:LOC114327215 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7R8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/50390:LOC114331663 ^@ http://purl.uniprot.org/uniprot/A0A6P7FW07 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1 family. CLIP subfamily.|||Secreted|||The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure. http://togogenome.org/gene/50390:LOC114333222 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1G2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/50390:LOC114328661 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBT0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/50390:LOC114326678 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5A5|||http://purl.uniprot.org/uniprot/A0A6P7FBT8 ^@ Similarity ^@ Belongs to the APC15 family. http://togogenome.org/gene/50390:LOC114334462 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZT4 ^@ Similarity ^@ Belongs to the thymidylate synthase family. http://togogenome.org/gene/50390:LOC114349402 ^@ http://purl.uniprot.org/uniprot/A0A6P7HIX3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/50390:LOC114331213 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKI9|||http://purl.uniprot.org/uniprot/A0A6P7FUT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family. Mth subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114327744 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8Y1|||http://purl.uniprot.org/uniprot/A0A6P7FBQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/50390:LOC114332265 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ87 ^@ Similarity ^@ Belongs to the MIF family. http://togogenome.org/gene/50390:LOC114334959 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8S8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family. http://togogenome.org/gene/50390:LOC114324650 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZ94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PCNA family.|||Nucleus|||This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. http://togogenome.org/gene/50390:LOC114332474 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPE8|||http://purl.uniprot.org/uniprot/A0A6P7G056 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Musashi family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114327306 ^@ http://purl.uniprot.org/uniprot/A0A6P7FA73|||http://purl.uniprot.org/uniprot/A0A6P7FEB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114326034 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8M2 ^@ Similarity ^@ Belongs to the spermidine/spermine synthase family. http://togogenome.org/gene/50390:LOC114326415 ^@ http://purl.uniprot.org/uniprot/A0A6P7F543 ^@ Similarity ^@ Belongs to the WD repeat L(2)GL family. http://togogenome.org/gene/50390:LOC114333431 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWC9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114349403 ^@ http://purl.uniprot.org/uniprot/A0A6P7H0Q4 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/50390:LOC114331603 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLW0|||http://purl.uniprot.org/uniprot/A0A6P7FQG1 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/50390:LOC114324536 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2V9|||http://purl.uniprot.org/uniprot/A0A6P7F361 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphorylase b kinase regulatory chain family.|||Cell membrane|||Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. http://togogenome.org/gene/50390:LOC114326473 ^@ http://purl.uniprot.org/uniprot/A0A6P7F740 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114337496 ^@ http://purl.uniprot.org/uniprot/A0A6P7G429|||http://purl.uniprot.org/uniprot/A0A6P7GFH0|||http://purl.uniprot.org/uniprot/A0A6P7GJ06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Membrane http://togogenome.org/gene/50390:LOC114333148 ^@ http://purl.uniprot.org/uniprot/A0A6P7G124|||http://purl.uniprot.org/uniprot/A0A6P7G2F1 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/50390:LOC114337037 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8I6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 45 (cellulase K) family. http://togogenome.org/gene/50390:LOC114326350 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6L9 ^@ Similarity ^@ Belongs to the DPCD family. http://togogenome.org/gene/50390:LOC114339190 ^@ http://purl.uniprot.org/uniprot/A0A6P7GPC1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/50390:LOC114325387 ^@ http://purl.uniprot.org/uniprot/A0A6P7F739 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFS5 subunit family.|||Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114327555 ^@ http://purl.uniprot.org/uniprot/A0A6P7F910 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic PMM family.|||Cytoplasm|||Homodimer.|||Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. http://togogenome.org/gene/50390:LOC114344166 ^@ http://purl.uniprot.org/uniprot/A0A6P7GZF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCRIP family.|||Nucleus|||Stress granule http://togogenome.org/gene/50390:LOC114346985 ^@ http://purl.uniprot.org/uniprot/A0A6P7H733 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCF/LEF family.|||Nucleus http://togogenome.org/gene/50390:LOC114327123 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7F6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PDE6D/unc-119 family.|||Cytoplasm|||Interacts with Pde6.|||Nucleus http://togogenome.org/gene/50390:LOC114335665 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYS2|||http://purl.uniprot.org/uniprot/A0A6P7FYZ2|||http://purl.uniprot.org/uniprot/A0A6P7G401|||http://purl.uniprot.org/uniprot/A0A6P7GA82|||http://purl.uniprot.org/uniprot/A0A6P7GA88|||http://purl.uniprot.org/uniprot/A0A6P7GBL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNOT2/3/5 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114329239 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDI8 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114325613 ^@ http://purl.uniprot.org/uniprot/A0A6P7F3U0 ^@ Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/50390:LOC114333487 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWJ3 ^@ Similarity ^@ Belongs to the DENR family. http://togogenome.org/gene/50390:LOC114330651 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.|||nucleolus http://togogenome.org/gene/50390:LOC114325166 ^@ http://purl.uniprot.org/uniprot/A0A6P7F090|||http://purl.uniprot.org/uniprot/A0A6P7F0Y6|||http://purl.uniprot.org/uniprot/A0A6P7F257|||http://purl.uniprot.org/uniprot/A0A6P7F264|||http://purl.uniprot.org/uniprot/A0A6P7F272 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphoglycerate mutase family. http://togogenome.org/gene/50390:LOC114329603 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin family. SUMO subfamily.|||Nucleus http://togogenome.org/gene/50390:LOC114332116 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMX0 ^@ Similarity ^@ Belongs to the RENT3 family. http://togogenome.org/gene/50390:LOC114346223 ^@ http://purl.uniprot.org/uniprot/A0A6P7GTH7|||http://purl.uniprot.org/uniprot/A0A6P7H2R4|||http://purl.uniprot.org/uniprot/A0A6P7H545 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AXUD1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114331529 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVF7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 30 family. http://togogenome.org/gene/50390:LOC114326391 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNOT9 family.|||P-body http://togogenome.org/gene/50390:LOC114339411 ^@ http://purl.uniprot.org/uniprot/A0A6P7GIT9 ^@ Similarity ^@ Belongs to the major royal jelly protein family. http://togogenome.org/gene/50390:LOC114327504 ^@ http://purl.uniprot.org/uniprot/A0A6P7F826|||http://purl.uniprot.org/uniprot/A0A6P7FF23 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic AdoMetDC family.|||Binds 1 pyruvoyl group covalently per subunit. http://togogenome.org/gene/50390:LOC114332552 ^@ http://purl.uniprot.org/uniprot/A0A6P7FP98 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/50390:LOC114324284 ^@ http://purl.uniprot.org/uniprot/A0A6P7EY14 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114337597 ^@ http://purl.uniprot.org/uniprot/A0A6P7GJD2 ^@ Subcellular Location Annotation ^@ Recycling endosome http://togogenome.org/gene/50390:LOC114331760 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114332100 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYJ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EBP2 family.|||Required for the processing of the 27S pre-rRNA.|||nucleolus http://togogenome.org/gene/50390:LOC114331651 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLZ8 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1 family. CLIP subfamily.|||Secreted|||The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure. http://togogenome.org/gene/50390:LOC114334236 ^@ http://purl.uniprot.org/uniprot/A0A6P7G520 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/50390:LOC114327434 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the universal ribosomal protein uS2 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with ribosomal protein S21.|||Cytoplasm|||Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. http://togogenome.org/gene/50390:LOC114327325 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7E8 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/50390:LOC114325436 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7A6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114333230 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/50390:LOC114327237 ^@ http://purl.uniprot.org/uniprot/A0A6P7FE04 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. http://togogenome.org/gene/50390:LOC114330054 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGH8|||http://purl.uniprot.org/uniprot/A0A6P7FGX2|||http://purl.uniprot.org/uniprot/A0A6P7FQ79|||http://purl.uniprot.org/uniprot/A0A6P7FQG8|||http://purl.uniprot.org/uniprot/A0A6P7FQH3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.|||Catalyzes the hydrolysis of ATP coupled with the transport of calcium.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114336385 ^@ http://purl.uniprot.org/uniprot/A0A6P7GEM6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS2/PSF2 family.|||Component of the GINS complex.|||Nucleus http://togogenome.org/gene/50390:LOC114338509 ^@ http://purl.uniprot.org/uniprot/A0A6P7GM99 ^@ Similarity ^@ Belongs to the AFG1 ATPase family. http://togogenome.org/gene/50390:LOC114332946 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQM3|||http://purl.uniprot.org/uniprot/A0A6P7G0E3 ^@ Similarity ^@ Belongs to the MAPRE family. http://togogenome.org/gene/50390:LOC114331606 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLU8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114326793 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8E1|||http://purl.uniprot.org/uniprot/A0A6P7F8L2 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/50390:LOC114349388 ^@ http://purl.uniprot.org/uniprot/A0A6P7HD45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PGAP2 family.|||Membrane http://togogenome.org/gene/50390:LOC114324329 ^@ http://purl.uniprot.org/uniprot/A0A6P7F351 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyadenylate-binding protein type-1 family.|||Binds the poly(A) tail of mRNA.|||Cytoplasm http://togogenome.org/gene/50390:LOC114344706 ^@ http://purl.uniprot.org/uniprot/A0A6P7H0U0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heat shock protein 70 family.|||Endoplasmic reticulum lumen http://togogenome.org/gene/50390:LOC114327135 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9J1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114328861 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKD6 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/50390:LOC114338869 ^@ http://purl.uniprot.org/uniprot/A0A6P7G8C2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114334178 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYX1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-II family.|||Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.|||Mitochondrion http://togogenome.org/gene/50390:LOC114333585 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2K7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.|||Cell membrane|||Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. http://togogenome.org/gene/50390:LOC114326347 ^@ http://purl.uniprot.org/uniprot/A0A6P7F481 ^@ Similarity|||Subcellular Location Annotation ^@ In the N-terminal section; belongs to the peroxidase family.|||Membrane http://togogenome.org/gene/50390:LOC114348869 ^@ http://purl.uniprot.org/uniprot/A0A6P7H932 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. http://togogenome.org/gene/50390:LOC114326522 ^@ http://purl.uniprot.org/uniprot/A0A6P7F793|||http://purl.uniprot.org/uniprot/A0A6P7FAZ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114333690 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSP2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. BUD32 family. http://togogenome.org/gene/50390:LOC114337344 ^@ http://purl.uniprot.org/uniprot/A0A6P7GEY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPP small subunits family. Sedlin subfamily.|||perinuclear region http://togogenome.org/gene/50390:LOC114328618 ^@ http://purl.uniprot.org/uniprot/A0A6P7FER9|||http://purl.uniprot.org/uniprot/A0A6P7FK35 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114330800 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIT7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/50390:LOC114324178 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYR3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily. http://togogenome.org/gene/50390:LOC114329331 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/50390:LOC114328906 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFK3 ^@ Function|||Similarity ^@ Belongs to the diphthine synthase family.|||S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis. http://togogenome.org/gene/50390:LOC114329806 ^@ http://purl.uniprot.org/uniprot/A0A6P7FG61|||http://purl.uniprot.org/uniprot/A0A6P7FIP0|||http://purl.uniprot.org/uniprot/A0A6P7FPF9 ^@ Subcellular Location Annotation ^@ Membrane|||secretory vesicle membrane http://togogenome.org/gene/50390:LOC114334913 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWN6 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/50390:LOC114324166 ^@ http://purl.uniprot.org/uniprot/A0A6P7EYP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114344732 ^@ http://purl.uniprot.org/uniprot/A0A6P7GP12|||http://purl.uniprot.org/uniprot/A0A6P7H0V7 ^@ Function|||Similarity ^@ Belongs to the DNA glycosylase MPG family.|||Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. http://togogenome.org/gene/50390:LOC114334928 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWP8 ^@ Similarity|||Subunit ^@ Belongs to the ubiquitin-activating E1 family.|||Heterodimer. http://togogenome.org/gene/50390:LOC114337183 ^@ http://purl.uniprot.org/uniprot/A0A6P7G389 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ninjurin family.|||Membrane http://togogenome.org/gene/50390:LOC114335518 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYJ1|||http://purl.uniprot.org/uniprot/A0A6P7G9S9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NFYA/HAP2 subunit family.|||Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.|||Heterotrimer.|||Nucleus http://togogenome.org/gene/50390:LOC114328020 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.|||Belongs to the RAP1 family.|||Homodimer.|||Nucleus|||telomere http://togogenome.org/gene/50390:LOC114327609 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBA2 ^@ Similarity ^@ Belongs to the TDD superfamily. DTWD2 family. http://togogenome.org/gene/50390:LOC114327014 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6E0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/50390:LOC114333428 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3F3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114339139 ^@ http://purl.uniprot.org/uniprot/A0A6P7GK36 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114333768 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXL7 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/50390:LOC114340388 ^@ http://purl.uniprot.org/uniprot/A0A6P7GC92 ^@ Similarity ^@ Belongs to the DAMOX/DASOX family. http://togogenome.org/gene/50390:LOC114331031 ^@ http://purl.uniprot.org/uniprot/A0A6P7FTL4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114330380 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHZ1 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL11 family.|||Binds directly to 26S ribosomal RNA. http://togogenome.org/gene/50390:LOC114329567 ^@ http://purl.uniprot.org/uniprot/A0A6P7FER6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PurH family.|||cytosol http://togogenome.org/gene/50390:LOC114330025 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQ98 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114333551 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSG4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114329147 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGF0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS2 family.|||Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114334079 ^@ http://purl.uniprot.org/uniprot/A0A6P7G5T5 ^@ Cofactor|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/50390:LOC114326238 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9Q7 ^@ Similarity ^@ Belongs to the UBALD family. http://togogenome.org/gene/50390:LOC114326376 ^@ http://purl.uniprot.org/uniprot/A0A6P7F507|||http://purl.uniprot.org/uniprot/A0A6P7F6R5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114331526 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SPT4 family.|||Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.|||Nucleus http://togogenome.org/gene/50390:LOC114327303 ^@ http://purl.uniprot.org/uniprot/A0A6P7F839 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/50390:LOC114327540 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family.|||Nucleus http://togogenome.org/gene/50390:LOC114327039 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6G6|||http://purl.uniprot.org/uniprot/A0A6P7FD68 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CybS family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114327539 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFI6 ^@ Similarity ^@ Belongs to the SPT2 family. http://togogenome.org/gene/50390:LOC114335683 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ15|||http://purl.uniprot.org/uniprot/A0A6P7G428|||http://purl.uniprot.org/uniprot/A0A6P7GAB3|||http://purl.uniprot.org/uniprot/A0A6P7GBP5 ^@ Similarity ^@ Belongs to the major royal jelly protein family. http://togogenome.org/gene/50390:LOC114329788 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFJ4|||http://purl.uniprot.org/uniprot/A0A6P7FG38|||http://purl.uniprot.org/uniprot/A0A6P7FIL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CARMIL family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114326883 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5X7 ^@ Function|||Similarity|||Subunit ^@ Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.|||Belongs to the cyclin family. Cyclin C subfamily.|||Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. http://togogenome.org/gene/50390:LOC114325396 ^@ http://purl.uniprot.org/uniprot/A0A6P7F100|||http://purl.uniprot.org/uniprot/A0A6P7F665 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C54 family.|||Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.|||Cytoplasm http://togogenome.org/gene/50390:LOC114325167 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0W9|||http://purl.uniprot.org/uniprot/A0A6P7F5B8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily. http://togogenome.org/gene/50390:LOC114333484 ^@ http://purl.uniprot.org/uniprot/A0A6P7FS22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the proteasome subunit S2 family.|||Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).|||Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. http://togogenome.org/gene/50390:LOC114327317 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7D9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.|||Component of the pre-66S ribosomal particle.|||Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.|||nucleolus http://togogenome.org/gene/50390:LOC114349352 ^@ http://purl.uniprot.org/uniprot/A0A6P7H1U7|||http://purl.uniprot.org/uniprot/A0A6P7HD04 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/50390:LOC114349528 ^@ http://purl.uniprot.org/uniprot/A0A6P7H2S4|||http://purl.uniprot.org/uniprot/A0A6P7HJH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114346367 ^@ http://purl.uniprot.org/uniprot/A0A6P7H354 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/50390:LOC114333388 ^@ http://purl.uniprot.org/uniprot/A0A6P7FW86 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114332200 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNM6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114329328 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDV6|||http://purl.uniprot.org/uniprot/A0A6P7FMA6 ^@ Similarity ^@ Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily. http://togogenome.org/gene/50390:LOC114340339 ^@ http://purl.uniprot.org/uniprot/A0A6P7GBY8|||http://purl.uniprot.org/uniprot/A0A6P7GSU1 ^@ Similarity ^@ Belongs to the TEL2 family. http://togogenome.org/gene/50390:LOC114332483 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the organo anion transporter (TC 2.A.60) family.|||Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114330981 ^@ http://purl.uniprot.org/uniprot/A0A6P7FN54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NPC2 family.|||Secreted http://togogenome.org/gene/50390:LOC114333543 ^@ http://purl.uniprot.org/uniprot/A0A6P7FSF8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KISH family.|||Golgi apparatus membrane|||Involved in the early part of the secretory pathway.|||Membrane http://togogenome.org/gene/50390:LOC114332170 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZRANB2 family.|||Nucleus http://togogenome.org/gene/50390:LOC114328612 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBM2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114332771 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the syndecan proteoglycan family.|||Cell surface proteoglycan.|||Membrane http://togogenome.org/gene/50390:LOC114327826 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Nucleus http://togogenome.org/gene/50390:LOC114339103 ^@ http://purl.uniprot.org/uniprot/A0A6P7GK03 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/50390:LOC114330071 ^@ http://purl.uniprot.org/uniprot/A0A6P7FJJ6|||http://purl.uniprot.org/uniprot/A0A6P7FQA4|||http://purl.uniprot.org/uniprot/A0A6P7FQJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Golgi apparatus|||clathrin-coated pit http://togogenome.org/gene/50390:LOC114329337 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114335707 ^@ http://purl.uniprot.org/uniprot/A0A6P7GBS9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TAM41 family.|||Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114324849 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZU1|||http://purl.uniprot.org/uniprot/A0A6P7F0W0|||http://purl.uniprot.org/uniprot/A0A6P7F4Y8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/50390:LOC114339911 ^@ http://purl.uniprot.org/uniprot/A0A6P7GMJ0 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 2 family.|||Homotetramer.|||Inhibited by L-aspartic acid.|||Plays an important role in the degradation of dermatan and keratan sulfates. http://togogenome.org/gene/50390:LOC114332631 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPH7 ^@ Function|||Similarity ^@ Belongs to the NARF family.|||Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. http://togogenome.org/gene/50390:LOC114338957 ^@ http://purl.uniprot.org/uniprot/A0A6P7GHP3 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. http://togogenome.org/gene/50390:LOC114332385 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNP6|||http://purl.uniprot.org/uniprot/A0A6P7FYS3|||http://purl.uniprot.org/uniprot/A0A6P7FZQ9 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/50390:LOC114325872 ^@ http://purl.uniprot.org/uniprot/A0A6P7F368 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 6A family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114337768 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4Y6|||http://purl.uniprot.org/uniprot/A0A6P7GGB2|||http://purl.uniprot.org/uniprot/A0A6P7GK00 ^@ Function|||Similarity ^@ Belongs to the sorting nexin family.|||Involved in several stages of intracellular trafficking. http://togogenome.org/gene/50390:LOC114333335 ^@ http://purl.uniprot.org/uniprot/A0A6P7G313 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the hedgehog family.|||Cell membrane|||Cytoplasm|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Interacts with shf.|||Membrane|||The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.|||The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development. http://togogenome.org/gene/50390:LOC114331542 ^@ http://purl.uniprot.org/uniprot/A0A6P7FWE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CLPTM1 family.|||Membrane http://togogenome.org/gene/50390:LOC114336543 ^@ http://purl.uniprot.org/uniprot/A0A6P7GF83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GINS4/SLD5 family.|||Nucleus|||The GINS complex plays an essential role in the initiation of DNA replication. http://togogenome.org/gene/50390:LOC114330278 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRA6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114330688 ^@ http://purl.uniprot.org/uniprot/A0A6P7FIH4|||http://purl.uniprot.org/uniprot/A0A6P7FSD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the round spermatid basic protein 1 family.|||Nucleus http://togogenome.org/gene/50390:LOC114332971 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQQ2 ^@ Similarity ^@ Belongs to the helicase family. http://togogenome.org/gene/50390:LOC114331433 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cecropin family.|||Secreted http://togogenome.org/gene/50390:LOC114338797 ^@ http://purl.uniprot.org/uniprot/A0A6P7GJ26 ^@ Similarity ^@ Belongs to the fl(2)d family. http://togogenome.org/gene/50390:LOC114336743 ^@ http://purl.uniprot.org/uniprot/A0A6P7G203|||http://purl.uniprot.org/uniprot/A0A6P7G7G6|||http://purl.uniprot.org/uniprot/A0A6P7GDC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114347815 ^@ http://purl.uniprot.org/uniprot/A0A6P7GXM1|||http://purl.uniprot.org/uniprot/A0A6P7H6Y4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114325561 ^@ http://purl.uniprot.org/uniprot/A0A6P7F265|||http://purl.uniprot.org/uniprot/A0A6P7F3M0|||http://purl.uniprot.org/uniprot/A0A6P7F6V7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/50390:LOC114330787 ^@ http://purl.uniprot.org/uniprot/A0A6P7FT88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-beta family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/50390:LOC114327262 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9Z0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DUOXA family.|||Membrane http://togogenome.org/gene/50390:LOC114333857 ^@ http://purl.uniprot.org/uniprot/A0A6P7G556 ^@ Caution|||Cofactor ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114333620 ^@ http://purl.uniprot.org/uniprot/A0A6P7FX09 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/50390:LOC114337487 ^@ http://purl.uniprot.org/uniprot/A0A6P7GA68 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit alpha family. http://togogenome.org/gene/50390:LOC114336160 ^@ http://purl.uniprot.org/uniprot/A0A6P7GDQ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).|||Cytoplasm|||Nucleus http://togogenome.org/gene/50390:LOC114333156 ^@ http://purl.uniprot.org/uniprot/A0A6P7FVM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CLUAP1 family.|||cilium http://togogenome.org/gene/50390:LOC114333835 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXS8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114327508 ^@ http://purl.uniprot.org/uniprot/A0A6P7F832|||http://purl.uniprot.org/uniprot/A0A6P7FF28 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/50390:LOC114344833 ^@ http://purl.uniprot.org/uniprot/A0A6P7H679 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/50390:LOC114333409 ^@ http://purl.uniprot.org/uniprot/A0A6P7G202 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/50390:LOC114326414 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6V5|||http://purl.uniprot.org/uniprot/A0A6P7FAT5|||http://purl.uniprot.org/uniprot/A0A6P7FAT9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/50390:LOC114336536 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1G4|||http://purl.uniprot.org/uniprot/A0A6P7GF78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114333326 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRJ9|||http://purl.uniprot.org/uniprot/A0A6P7FRT3|||http://purl.uniprot.org/uniprot/A0A6P7FW31|||http://purl.uniprot.org/uniprot/A0A6P7G302 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin beta chain family.|||Cell membrane|||Membrane http://togogenome.org/gene/50390:LOC114329684 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/50390:LOC114332352 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZM0 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/50390:LOC114325544 ^@ http://purl.uniprot.org/uniprot/A0A6P7F253|||http://purl.uniprot.org/uniprot/A0A6P7F3K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114332275 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNW6 ^@ Similarity ^@ Belongs to the CSN9 family. http://togogenome.org/gene/50390:LOC114337533 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4E6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.|||Cell membrane http://togogenome.org/gene/50390:LOC114341791 ^@ http://purl.uniprot.org/uniprot/A0A6P7GFI8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/50390:LOC114327169 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6T4|||http://purl.uniprot.org/uniprot/A0A6P7FDP8 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/50390:LOC114344136 ^@ http://purl.uniprot.org/uniprot/A0A6P7GXJ9 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/50390:LOC114343535 ^@ http://purl.uniprot.org/uniprot/A0A6P7GKL0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Mitochondrion|||Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits. http://togogenome.org/gene/50390:LOC114325910 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2J4|||http://purl.uniprot.org/uniprot/A0A6P7F3B4|||http://purl.uniprot.org/uniprot/A0A6P7F851|||http://purl.uniprot.org/uniprot/A0A6P7F8S7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10A family.|||Binds 2 Zn(2+) ions per subunit.|||Can bind about 5 Ca(2+) ions per subunit. http://togogenome.org/gene/50390:LOC114325571 ^@ http://purl.uniprot.org/uniprot/A0A6P7F1H6|||http://purl.uniprot.org/uniprot/A0A6P7F6X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/50390:LOC114336977 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2M1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family. http://togogenome.org/gene/50390:LOC114326515 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5F4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114332060 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMQ4|||http://purl.uniprot.org/uniprot/A0A6P7FS04|||http://purl.uniprot.org/uniprot/A0A6P7FXH3 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/50390:LOC114333728 ^@ http://purl.uniprot.org/uniprot/A0A6P7G4M3 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/50390:LOC114335232 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AROS family.|||nucleolus http://togogenome.org/gene/50390:LOC114329070 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLB2 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/50390:LOC114329394 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMR1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/50390:LOC114329759 ^@ http://purl.uniprot.org/uniprot/A0A6P7FP57 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 2 family. http://togogenome.org/gene/50390:LOC114326945 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCW0 ^@ Function|||Similarity ^@ Belongs to the IPP isomerase type 1 family.|||Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). http://togogenome.org/gene/50390:LOC114330375 ^@ http://purl.uniprot.org/uniprot/A0A6P7FHY6 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/50390:LOC114335356 ^@ http://purl.uniprot.org/uniprot/A0A6P7GA98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RED family.|||Nucleus http://togogenome.org/gene/50390:LOC114326386 ^@ http://purl.uniprot.org/uniprot/A0A6P7F6S9 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/50390:LOC114326772 ^@ http://purl.uniprot.org/uniprot/A0A6P7F852|||http://purl.uniprot.org/uniprot/A0A6P7FC05 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.|||Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP. http://togogenome.org/gene/50390:LOC114324177 ^@ http://purl.uniprot.org/uniprot/A0A6P7F2H9 ^@ Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily. http://togogenome.org/gene/50390:LOC114337758 ^@ http://purl.uniprot.org/uniprot/A0A6P7GGA4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NADP-dependent oxidoreductase L4BD family.|||Cytoplasm|||Monomer or homodimer. http://togogenome.org/gene/50390:LOC114335657 ^@ http://purl.uniprot.org/uniprot/A0A6P7FYX6|||http://purl.uniprot.org/uniprot/A0A6P7GBJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family. RecQ subfamily.|||Nucleus http://togogenome.org/gene/50390:LOC114325163 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/50390:LOC114326466 ^@ http://purl.uniprot.org/uniprot/A0A6P7FB19 ^@ Similarity ^@ Belongs to the glutamate--cysteine ligase type 3 family. http://togogenome.org/gene/50390:LOC114329221 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGN0 ^@ Similarity ^@ Belongs to the VPS13 family. http://togogenome.org/gene/50390:LOC114331861 ^@ http://purl.uniprot.org/uniprot/A0A6P7FRD0|||http://purl.uniprot.org/uniprot/A0A6P7FWT5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/50390:LOC114345853 ^@ http://purl.uniprot.org/uniprot/A0A6P7H1X7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/50390:LOC114334243 ^@ http://purl.uniprot.org/uniprot/A0A6P7FZ39 ^@ Similarity ^@ Belongs to the proteasome subunit S5A family. http://togogenome.org/gene/50390:LOC114334459 ^@ http://purl.uniprot.org/uniprot/A0A6P7FV16 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/50390:LOC114327425 ^@ http://purl.uniprot.org/uniprot/A0A6P7F8I9|||http://purl.uniprot.org/uniprot/A0A6P7FAM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit A family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. http://togogenome.org/gene/50390:LOC114341233 ^@ http://purl.uniprot.org/uniprot/A0A6P7GE60|||http://purl.uniprot.org/uniprot/A0A6P7GE67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CMC family.|||Mitochondrion http://togogenome.org/gene/50390:LOC114324494 ^@ http://purl.uniprot.org/uniprot/A0A6P7EY82|||http://purl.uniprot.org/uniprot/A0A6P7F2N7|||http://purl.uniprot.org/uniprot/A0A6P7F3T2|||http://purl.uniprot.org/uniprot/A0A6P7F3V0 ^@ Similarity ^@ Belongs to the IST1 family. http://togogenome.org/gene/50390:LOC114324667 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0E4 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. ATM subfamily. http://togogenome.org/gene/50390:LOC114327475 ^@ http://purl.uniprot.org/uniprot/A0A6P7FAT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFC2 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/50390:LOC114325714 ^@ http://purl.uniprot.org/uniprot/A0A6P7F486 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/50390:LOC114329799 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPE6 ^@ Similarity ^@ Belongs to the CMC4 family. http://togogenome.org/gene/50390:LOC114331098 ^@ http://purl.uniprot.org/uniprot/A0A290WIE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes medium subunit family.|||Cell membrane|||coated pit http://togogenome.org/gene/50390:LOC114344108 ^@ http://purl.uniprot.org/uniprot/A0A6P7H430 ^@ Similarity ^@ Belongs to the NAC-beta family. http://togogenome.org/gene/50390:LOC114341246 ^@ http://purl.uniprot.org/uniprot/A0A6P7GE70|||http://purl.uniprot.org/uniprot/A0A6P7GE90|||http://purl.uniprot.org/uniprot/A0A6P7GEA5|||http://purl.uniprot.org/uniprot/A0A6P7GRH2|||http://purl.uniprot.org/uniprot/A0A6P7GRI9 ^@ Similarity ^@ Belongs to the LSM14 family. http://togogenome.org/gene/50390:LOC114331674 ^@ http://purl.uniprot.org/uniprot/A0A6P7FLK4 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1 family. CLIP subfamily.|||Secreted|||The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure. http://togogenome.org/gene/50390:LOC114330259 ^@ http://purl.uniprot.org/uniprot/A0A6P7FH43 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/50390:LOC114329606 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEW7|||http://purl.uniprot.org/uniprot/A0A6P7FNQ2 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/50390:LOC114340944 ^@ http://purl.uniprot.org/uniprot/A0A6P7GQL5 ^@ Similarity ^@ Belongs to the CSN12 family. http://togogenome.org/gene/50390:LOC114332622 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPG4 ^@ Similarity ^@ Belongs to the endosulfine family. http://togogenome.org/gene/50390:LOC114336452 ^@ http://purl.uniprot.org/uniprot/A0A6P7G138|||http://purl.uniprot.org/uniprot/A0A6P7G6J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP-dependent AMP-binding enzyme family.|||Peroxisome http://togogenome.org/gene/50390:LOC114347236 ^@ http://purl.uniprot.org/uniprot/A0A6P7GVL8 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/50390:LOC114333536 ^@ http://purl.uniprot.org/uniprot/A0A6P7FS64|||http://purl.uniprot.org/uniprot/A0A6P7G2E8|||http://purl.uniprot.org/uniprot/A0A6P7G3S8 ^@ Caution|||Function ^@ Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114329047 ^@ http://purl.uniprot.org/uniprot/A0A6P7FL89 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/50390:LOC114327483 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VOPP1/ECOP family.|||Cytoplasmic vesicle membrane|||Endosome membrane|||Late endosome membrane|||Lysosome membrane|||Membrane http://togogenome.org/gene/50390:LOC114332384 ^@ http://purl.uniprot.org/uniprot/A0A6P7FT61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX17 family.|||Mitochondrion intermembrane space http://togogenome.org/gene/50390:LOC114331131 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUI8 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/50390:LOC114332818 ^@ http://purl.uniprot.org/uniprot/A0A6P7FQ92|||http://purl.uniprot.org/uniprot/A0A6P7FUB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/50390:LOC114324444 ^@ http://purl.uniprot.org/uniprot/A0A6P7EY32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ARPC3 family.|||Component of the Arp2/3 complex.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.|||cytoskeleton http://togogenome.org/gene/50390:LOC114339946 ^@ http://purl.uniprot.org/uniprot/A0A6P7GB91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG3 family.|||Cytoplasm http://togogenome.org/gene/50390:LOC114331877 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMN6 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Catalytic component of the tRNA-splicing ligase complex.|||Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.|||Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP. http://togogenome.org/gene/50390:LOC114333802 ^@ http://purl.uniprot.org/uniprot/A0A6P7G3L1 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/50390:LOC114328378 ^@ http://purl.uniprot.org/uniprot/A0A6P7FBN8|||http://purl.uniprot.org/uniprot/A0A6P7FDV5 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/50390:LOC114326833 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5S6 ^@ Similarity ^@ Belongs to the CFAP45 family. http://togogenome.org/gene/50390:LOC114332648 ^@ http://purl.uniprot.org/uniprot/A0A6P7FPY3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/50390:LOC114333189 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1D1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP family.|||Membrane|||Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. http://togogenome.org/gene/50390:LOC114347997 ^@ http://purl.uniprot.org/uniprot/A0A6P7GYD0|||http://purl.uniprot.org/uniprot/A0A6P7GYD5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114324171 ^@ http://purl.uniprot.org/uniprot/A0A6P7EX62 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/50390:LOC114349518 ^@ http://purl.uniprot.org/uniprot/A0A6P7HAL0 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/50390:LOC114326932 ^@ http://purl.uniprot.org/uniprot/A0A6P7FCP4 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/50390:LOC114330801 ^@ http://purl.uniprot.org/uniprot/A0A6P7FM86 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/50390:LOC114333501 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2B0 ^@ Similarity ^@ Belongs to the SH3BP5 family. http://togogenome.org/gene/50390:LOC114329438 ^@ http://purl.uniprot.org/uniprot/A0A6P7FEA3|||http://purl.uniprot.org/uniprot/A0A6P7FEB0|||http://purl.uniprot.org/uniprot/A0A6P7FF09|||http://purl.uniprot.org/uniprot/A0A6P7FHE2|||http://purl.uniprot.org/uniprot/A0A6P7FMU3|||http://purl.uniprot.org/uniprot/A0A6P7FMU7|||http://purl.uniprot.org/uniprot/A0A6P7FMW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/50390:LOC114326688 ^@ http://purl.uniprot.org/uniprot/A0A6P7F5C4|||http://purl.uniprot.org/uniprot/A0A6P7FBW1 ^@ Similarity ^@ Belongs to the FAH family. http://togogenome.org/gene/50390:LOC114334842 ^@ http://purl.uniprot.org/uniprot/A0A6P7G885 ^@ Function|||Similarity ^@ Belongs to the WD repeat WDR48 family.|||Regulator of deubiquitinating complexes. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate. http://togogenome.org/gene/50390:LOC114324191 ^@ http://purl.uniprot.org/uniprot/A0A6P7EX90 ^@ Similarity ^@ Belongs to the ODR-4 family. http://togogenome.org/gene/50390:LOC114338783 ^@ http://purl.uniprot.org/uniprot/A0A6P7G7V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cecropin family.|||Secreted http://togogenome.org/gene/50390:LOC114325432 ^@ http://purl.uniprot.org/uniprot/A0A6P7F340 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114328968 ^@ http://purl.uniprot.org/uniprot/A0A6P7FFT4 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/50390:LOC114329072 ^@ http://purl.uniprot.org/uniprot/A0A6P7FG49 ^@ Similarity ^@ Belongs to the NKAP family. http://togogenome.org/gene/50390:LOC114327264 ^@ http://purl.uniprot.org/uniprot/A0A6P7F9Z5 ^@ Similarity ^@ In the C-terminal section; belongs to the peptidase M41 family.|||In the N-terminal section; belongs to the AAA ATPase family. http://togogenome.org/gene/50390:LOC114347524 ^@ http://purl.uniprot.org/uniprot/A0A6P7GX19 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 30 family. http://togogenome.org/gene/50390:LOC114331835 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXM5 ^@ Caution|||Similarity ^@ Belongs to the acylphosphatase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114332994 ^@ http://purl.uniprot.org/uniprot/A0A6P7G1T2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/50390:LOC114343206 ^@ http://purl.uniprot.org/uniprot/A0A6P7GJI7|||http://purl.uniprot.org/uniprot/A0A6P7H197 ^@ Similarity ^@ Belongs to the LplA family. http://togogenome.org/gene/50390:LOC114334230 ^@ http://purl.uniprot.org/uniprot/A0A6P7FUP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/50390:LOC114328766 ^@ http://purl.uniprot.org/uniprot/A0A6P7FKQ7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the citrate synthase family.|||Homodimer.|||Mitochondrion matrix http://togogenome.org/gene/50390:LOC114349419 ^@ http://purl.uniprot.org/uniprot/A0A6P7HDA2 ^@ Similarity ^@ Belongs to the RNR ribonuclease family. http://togogenome.org/gene/50390:LOC114331777 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXD0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114337057 ^@ http://purl.uniprot.org/uniprot/A0A6P7G2S1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/50390:LOC114324824 ^@ http://purl.uniprot.org/uniprot/A0A6P7F0S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NXF family.|||Cytoplasm|||nucleoplasm http://togogenome.org/gene/50390:LOC114332274 ^@ http://purl.uniprot.org/uniprot/A0A6P7FNF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/50390:LOC114338253 ^@ http://purl.uniprot.org/uniprot/A0A6P7GDZ5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL1 family. http://togogenome.org/gene/50390:LOC114324773 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/50390:LOC114329190 ^@ http://purl.uniprot.org/uniprot/A0A6P7FDC3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium channel (TC 1.A.1.10) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.|||Membrane http://togogenome.org/gene/50390:LOC114328104 ^@ http://purl.uniprot.org/uniprot/A0A6P7FA00|||http://purl.uniprot.org/uniprot/A0A6P7FHV2 ^@ Similarity ^@ Belongs to the LanC-like protein family. http://togogenome.org/gene/50390:LOC114330047 ^@ http://purl.uniprot.org/uniprot/A0A6P7FGV9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/50390:LOC114338143 ^@ http://purl.uniprot.org/uniprot/A0A6P7G647 ^@ Similarity ^@ In the C-terminal section; belongs to the sulfate adenylyltransferase family.|||In the N-terminal section; belongs to the APS kinase family. http://togogenome.org/gene/50390:LOC114331102 ^@ http://purl.uniprot.org/uniprot/A0A6P7FK54|||http://purl.uniprot.org/uniprot/A0A6P7FUF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. MFSD6 family.|||Membrane http://togogenome.org/gene/50390:LOC114333730 ^@ http://purl.uniprot.org/uniprot/A0A6P7FXH6 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/50390:LOC114337397 ^@ http://purl.uniprot.org/uniprot/A0A6P7G9T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/50390:LOC114324363 ^@ http://purl.uniprot.org/uniprot/A0A6P7EZE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/50390:LOC114327471 ^@ http://purl.uniprot.org/uniprot/A0A6P7F7Y6|||http://purl.uniprot.org/uniprot/A0A6P7F8P7|||http://purl.uniprot.org/uniprot/A0A6P7FAS7|||http://purl.uniprot.org/uniprot/A0A6P7FF71 ^@ Similarity|||Subunit ^@ Homotetramer.|||In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.|||In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. http://togogenome.org/gene/50390:LOC114325667 ^@ http://purl.uniprot.org/uniprot/A0A6P7F405 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NIPA family.|||Membrane http://togogenome.org/gene/50390:LOC114329356 ^@ http://purl.uniprot.org/uniprot/A0A6P7FMF2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. http://togogenome.org/gene/50390:LOC114346174 ^@ http://purl.uniprot.org/uniprot/A0A6P7GSG2|||http://purl.uniprot.org/uniprot/A0A6P7H2N8|||http://purl.uniprot.org/uniprot/A0A6P7H521 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 14 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus