http://togogenome.org/gene/508771:TGME49_313820 ^@ http://purl.uniprot.org/uniprot/S8EXU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_226400 ^@ http://purl.uniprot.org/uniprot/S8G5Z7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||apicoplast http://togogenome.org/gene/508771:TGME49_253880 ^@ http://purl.uniprot.org/uniprot/S8FDK9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/508771:TGME49_269460 ^@ http://purl.uniprot.org/uniprot/S8G9D7 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/508771:TGME49_275870 ^@ http://purl.uniprot.org/uniprot/S8F7S8 ^@ Similarity ^@ Belongs to the tubulin family. http://togogenome.org/gene/508771:TGME49_206360 ^@ http://purl.uniprot.org/uniprot/S8F5H0 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/508771:TGME49_253780 ^@ http://purl.uniprot.org/uniprot/S8FAG2 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I family. http://togogenome.org/gene/508771:TGME49_261760 ^@ http://purl.uniprot.org/uniprot/S8GM12 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/508771:TGME49_221670 ^@ http://purl.uniprot.org/uniprot/A0A125YHC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M24 family. SPT16 subfamily.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.|||Component of the FACT complex.|||Nucleus http://togogenome.org/gene/508771:TGME49_254370 ^@ http://purl.uniprot.org/uniprot/S8GT16 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_246550 ^@ http://purl.uniprot.org/uniprot/A0A125YQD9 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/508771:TGME49_271170 ^@ http://purl.uniprot.org/uniprot/S8F4R4 ^@ Similarity ^@ Belongs to the polyprenol kinase family. http://togogenome.org/gene/508771:TGME49_246540 ^@ http://purl.uniprot.org/uniprot/A0A125YTU2 ^@ Cofactor|||Subcellular Location Annotation ^@ Binds 1 heme c group covalently per subunit.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_217030 ^@ http://purl.uniprot.org/uniprot/A0A125YTH6 ^@ Similarity ^@ Belongs to the SDHAF4 family. http://togogenome.org/gene/508771:TGME49_249790 ^@ http://purl.uniprot.org/uniprot/A0A125YXT1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_260610 ^@ http://purl.uniprot.org/uniprot/A0A125YPG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/508771:TGME49_278890 ^@ http://purl.uniprot.org/uniprot/A0A125YWA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CASP family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/508771:TGME49_293460 ^@ http://purl.uniprot.org/uniprot/A0A125YQT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP-dependent DNA ligase family.|||Nucleus http://togogenome.org/gene/508771:TGME49_288930 ^@ http://purl.uniprot.org/uniprot/S8EZU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CND2 (condensin subunit 2) family.|||Chromosome|||Cytoplasm http://togogenome.org/gene/508771:TGME49_213410 ^@ http://purl.uniprot.org/uniprot/A0A125YSB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus http://togogenome.org/gene/508771:TGME49_261060 ^@ http://purl.uniprot.org/uniprot/S8GCK6 ^@ Similarity ^@ Belongs to the DPH1/DPH2 family. DPH1 subfamily. http://togogenome.org/gene/508771:TGME49_253090 ^@ http://purl.uniprot.org/uniprot/S8FAP9 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily. http://togogenome.org/gene/508771:TGME49_279370 ^@ http://purl.uniprot.org/uniprot/S8EVP7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_310630 ^@ http://purl.uniprot.org/uniprot/A0A125YLY1 ^@ Similarity ^@ Belongs to the CDK5RAP3 family. http://togogenome.org/gene/508771:TGME49_261520 ^@ http://purl.uniprot.org/uniprot/S8F4G9 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/508771:TGME49_204370 ^@ http://purl.uniprot.org/uniprot/A0A125YZA0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_240600 ^@ http://purl.uniprot.org/uniprot/A0A125YM67 ^@ Similarity ^@ Belongs to the chaperonin (HSP60) family. http://togogenome.org/gene/508771:TGME49_313550 ^@ http://purl.uniprot.org/uniprot/S8ERD4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/508771:TGME49_295040 ^@ http://purl.uniprot.org/uniprot/A0A125YVL8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_288680 ^@ http://purl.uniprot.org/uniprot/S8EZS4 ^@ Similarity ^@ Belongs to the AP endonuclease 2 family. http://togogenome.org/gene/508771:TGME49_248470 ^@ http://purl.uniprot.org/uniprot/S8EVG0 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/508771:TGME49_311290 ^@ http://purl.uniprot.org/uniprot/A0A125YHT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Membrane http://togogenome.org/gene/508771:TGME49_278460 ^@ http://purl.uniprot.org/uniprot/A0A125YKW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_206415 ^@ http://purl.uniprot.org/uniprot/S8F8P7 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/508771:TGME49_224220 ^@ http://purl.uniprot.org/uniprot/A0A125YNB3 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/508771:TGME49_285895 ^@ http://purl.uniprot.org/uniprot/S8F5H3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_220212 ^@ http://purl.uniprot.org/uniprot/S8F8P6 ^@ Similarity ^@ Belongs to the tRNA pseudouridine synthase TruA family. http://togogenome.org/gene/508771:TGME49_284530 ^@ http://purl.uniprot.org/uniprot/S8GQU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/508771:TGME49_231770 ^@ http://purl.uniprot.org/uniprot/A0A125YTP7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/508771:TGME49_270220 ^@ http://purl.uniprot.org/uniprot/S8EYA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGV family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_320700 ^@ http://purl.uniprot.org/uniprot/S8GSN6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_228110 ^@ http://purl.uniprot.org/uniprot/A0A125YYC5 ^@ Similarity ^@ Belongs to the TMEM14 family. http://togogenome.org/gene/508771:TGME49_205490 ^@ http://purl.uniprot.org/uniprot/A0A125YYS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/508771:TGME49_217910 ^@ http://purl.uniprot.org/uniprot/A0A125YRL3 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/508771:TGME49_215460 ^@ http://purl.uniprot.org/uniprot/A0A125YKH0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/508771:TGME49_264752 ^@ http://purl.uniprot.org/uniprot/S8EWG1 ^@ Similarity ^@ Belongs to the THADA family. http://togogenome.org/gene/508771:TGME49_280410 ^@ http://purl.uniprot.org/uniprot/A0A125YZR8 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_316280 ^@ http://purl.uniprot.org/uniprot/S8G252 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/508771:TGME49_209710 ^@ http://purl.uniprot.org/uniprot/S8F8Q0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/508771:TGME49_215950 ^@ http://purl.uniprot.org/uniprot/A0A125YHY4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_200320 ^@ http://purl.uniprot.org/uniprot/A0A125YSF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_227830 ^@ http://purl.uniprot.org/uniprot/S8EXW3 ^@ Similarity ^@ Belongs to the Tim44 family. http://togogenome.org/gene/508771:TGME49_318420 ^@ http://purl.uniprot.org/uniprot/A0A125YN27 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/508771:TGME49_260420 ^@ http://purl.uniprot.org/uniprot/S8F4A9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the NDC80/HEC1 family.|||Component of the NDC80 complex.|||Nucleus|||kinetochore http://togogenome.org/gene/508771:TGME49_275410 ^@ http://purl.uniprot.org/uniprot/S8ESM4 ^@ Similarity ^@ Belongs to the APC1 family. http://togogenome.org/gene/508771:TGME49_214920 ^@ http://purl.uniprot.org/uniprot/S8ESW8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_267410 ^@ http://purl.uniprot.org/uniprot/S8F259 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_259690 ^@ http://purl.uniprot.org/uniprot/A0A125YRV4 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/508771:TGME49_258120 ^@ http://purl.uniprot.org/uniprot/A0A125YS82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the pex2/pex10/pex12 family.|||Membrane|||Peroxisome membrane http://togogenome.org/gene/508771:TGME49_289600 ^@ http://purl.uniprot.org/uniprot/A0A125YQI4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/508771:TGME49_280530 ^@ http://purl.uniprot.org/uniprot/A0A125YLW3 ^@ Similarity ^@ Belongs to the TDD superfamily. DTWD2 family. http://togogenome.org/gene/508771:TGME49_240660 ^@ http://purl.uniprot.org/uniprot/S8FAJ5 ^@ Similarity ^@ Belongs to the EFG1 family. http://togogenome.org/gene/508771:TGME49_315680 ^@ http://purl.uniprot.org/uniprot/A0A125YGT9 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/508771:TGME49_275330 ^@ http://purl.uniprot.org/uniprot/S8GDB4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/508771:TGME49_258030 ^@ http://purl.uniprot.org/uniprot/A0A125YP50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-B family.|||Nucleus http://togogenome.org/gene/508771:TGME49_316520 ^@ http://purl.uniprot.org/uniprot/A0A125YVI1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. http://togogenome.org/gene/508771:TGME49_223690 ^@ http://purl.uniprot.org/uniprot/S8EX14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC7 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/508771:TGME49_273730 ^@ http://purl.uniprot.org/uniprot/S8GA67 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_299040 ^@ http://purl.uniprot.org/uniprot/A0A125YM28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGC family.|||Membrane http://togogenome.org/gene/508771:TGME49_216590 ^@ http://purl.uniprot.org/uniprot/S8ETD7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_257730 ^@ http://purl.uniprot.org/uniprot/S8F706 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/508771:TGME49_309380 ^@ http://purl.uniprot.org/uniprot/S8EV69 ^@ Similarity ^@ Belongs to the NUF2 family. http://togogenome.org/gene/508771:TGME49_250770 ^@ http://purl.uniprot.org/uniprot/A0A125YLG2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. eIF4A subfamily. http://togogenome.org/gene/508771:TGME49_205150 ^@ http://purl.uniprot.org/uniprot/S8GN60 ^@ Similarity ^@ Belongs to the RMD1/sif2 family. http://togogenome.org/gene/508771:TGME49_278850 ^@ http://purl.uniprot.org/uniprot/A0A125YWM0 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/508771:TGME49_216600 ^@ http://purl.uniprot.org/uniprot/S8EWW1 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/508771:TGME49_286790 ^@ http://purl.uniprot.org/uniprot/S8F8B5 ^@ Similarity ^@ Belongs to the pinin family. http://togogenome.org/gene/508771:TGME49_289300 ^@ http://purl.uniprot.org/uniprot/S8G878 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_238190 ^@ http://purl.uniprot.org/uniprot/A0A125YK37 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/508771:TGME49_222000 ^@ http://purl.uniprot.org/uniprot/S8GJK5 ^@ Similarity ^@ Belongs to the BRX1 family. http://togogenome.org/gene/508771:TGME49_222310 ^@ http://purl.uniprot.org/uniprot/S8F851 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the plant tobamovirus multiplication TOM1 protein family.|||Membrane http://togogenome.org/gene/508771:TGME49_229990 ^@ http://purl.uniprot.org/uniprot/A0A125YJ02 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/508771:TGME49_306280 ^@ http://purl.uniprot.org/uniprot/A0A125YJP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 7 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/508771:TGME49_291090 ^@ http://purl.uniprot.org/uniprot/S8G8K3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family.|||Nucleus http://togogenome.org/gene/508771:TGME49_232210 ^@ http://purl.uniprot.org/uniprot/S8GAR9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_224910 ^@ http://purl.uniprot.org/uniprot/S8EU94 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/508771:TGME49_315730 ^@ http://purl.uniprot.org/uniprot/S8G298 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the apicomplexan parasites AMA1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_269190 ^@ http://purl.uniprot.org/uniprot/A0A125YM60 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/508771:TGME49_269000 ^@ http://purl.uniprot.org/uniprot/S8EXU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_226640 ^@ http://purl.uniprot.org/uniprot/A0A125YHN8 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/508771:TGME49_259260 ^@ http://purl.uniprot.org/uniprot/S8F7C1 ^@ Similarity ^@ In the C-terminal section; belongs to the peptidase M41 family.|||In the N-terminal section; belongs to the AAA ATPase family. http://togogenome.org/gene/508771:TGME49_282200 ^@ http://purl.uniprot.org/uniprot/S8F9V4 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/508771:TGME49_207940 ^@ http://purl.uniprot.org/uniprot/S8F943 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/508771:TGME49_285950 ^@ http://purl.uniprot.org/uniprot/S8F8I2 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. http://togogenome.org/gene/508771:TGME49_310320 ^@ http://purl.uniprot.org/uniprot/A0A125YME5 ^@ Similarity ^@ Belongs to the calreticulin family. http://togogenome.org/gene/508771:TGME49_259220 ^@ http://purl.uniprot.org/uniprot/S8GLJ5 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/508771:TGME49_217670 ^@ http://purl.uniprot.org/uniprot/S8ER55 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family. http://togogenome.org/gene/508771:TGME49_244900 ^@ http://purl.uniprot.org/uniprot/A0A125YTA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_227050 ^@ http://purl.uniprot.org/uniprot/S8EXS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDK/BCKDK protein kinase family.|||Mitochondrion matrix http://togogenome.org/gene/508771:TGME49_210820 ^@ http://purl.uniprot.org/uniprot/A0A125YKS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/508771:TGME49_230820 ^@ http://purl.uniprot.org/uniprot/A0A125YX93 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/508771:TGME49_237220 ^@ http://purl.uniprot.org/uniprot/A0A125YTJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/508771:TGME49_310820 ^@ http://purl.uniprot.org/uniprot/A0A125YHA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associated with the spliceosome.|||Belongs to the SLU7 family.|||Involved in pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/508771:TGME49_288830 ^@ http://purl.uniprot.org/uniprot/S8EWS1 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/508771:TGME49_277270 ^@ http://purl.uniprot.org/uniprot/S8EWH6 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/508771:TGME49_222130 ^@ http://purl.uniprot.org/uniprot/S8GTZ6 ^@ Similarity ^@ Belongs to the STEEP1 family. http://togogenome.org/gene/508771:TGME49_295760 ^@ http://purl.uniprot.org/uniprot/A0A125YQF6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_223130 ^@ http://purl.uniprot.org/uniprot/S8FBC0 ^@ Function|||Similarity ^@ Belongs to the methyltransferase TRM13 family.|||tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His). http://togogenome.org/gene/508771:TGME49_263690 ^@ http://purl.uniprot.org/uniprot/S8GD98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ALG10 glucosyltransferase family.|||Membrane http://togogenome.org/gene/508771:TGME49_229150 ^@ http://purl.uniprot.org/uniprot/S8F381 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_316140 ^@ http://purl.uniprot.org/uniprot/A0A125YU08 ^@ Similarity ^@ Belongs to the MGR2 family. http://togogenome.org/gene/508771:TGME49_251500 ^@ http://purl.uniprot.org/uniprot/A0A125YRK5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit H family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_251850 ^@ http://purl.uniprot.org/uniprot/S8GAA8 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/508771:TGME49_205540 ^@ http://purl.uniprot.org/uniprot/S8GDR3 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/508771:TGME49_268340 ^@ http://purl.uniprot.org/uniprot/S8G8Z9 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/508771:TGME49_238995 ^@ http://purl.uniprot.org/uniprot/S8F7W7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/508771:TGME49_227450 ^@ http://purl.uniprot.org/uniprot/S8GFM7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. DCP2 subfamily. http://togogenome.org/gene/508771:TGME49_249290 ^@ http://purl.uniprot.org/uniprot/S8EP02 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/508771:TGME49_239720 ^@ http://purl.uniprot.org/uniprot/A0A125YMH9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/508771:TGME49_215590 ^@ http://purl.uniprot.org/uniprot/A0A125YI83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_216530 ^@ http://purl.uniprot.org/uniprot/S8ETD3 ^@ Similarity ^@ Belongs to the RRF family. http://togogenome.org/gene/508771:TGME49_265650 ^@ http://purl.uniprot.org/uniprot/S8EZ85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Enzyme with a broad specificity.|||Membrane http://togogenome.org/gene/508771:TGME49_236580 ^@ http://purl.uniprot.org/uniprot/A0A125YFG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Common component of the spliceosome and rRNA processing machinery.|||nucleolus http://togogenome.org/gene/508771:TGME49_264880 ^@ http://purl.uniprot.org/uniprot/S8F2L7 ^@ Function|||Similarity ^@ Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.|||Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8. http://togogenome.org/gene/508771:TGME49_319970 ^@ http://purl.uniprot.org/uniprot/A0A125YIH0 ^@ Caution|||Similarity ^@ Belongs to the peptidase S8 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_202360 ^@ http://purl.uniprot.org/uniprot/S8F669 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. METL family. http://togogenome.org/gene/508771:TGME49_232010 ^@ http://purl.uniprot.org/uniprot/S8EZU1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Enzyme with a broad specificity.|||Membrane http://togogenome.org/gene/508771:TGME49_292130 ^@ http://purl.uniprot.org/uniprot/A0A125YU06 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/508771:TGME49_219140 ^@ http://purl.uniprot.org/uniprot/A0A125YHV2 ^@ Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family. http://togogenome.org/gene/508771:TGME49_240390 ^@ http://purl.uniprot.org/uniprot/S8F4I4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_203440 ^@ http://purl.uniprot.org/uniprot/S8GNH3 ^@ Similarity ^@ Belongs to the APC10 family. http://togogenome.org/gene/508771:TGME49_268650 ^@ http://purl.uniprot.org/uniprot/S8F0V8 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/508771:TGME49_255320 ^@ http://purl.uniprot.org/uniprot/A0A125YTV0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with the pre-60S ribosomal particle.|||Belongs to the universal ribosomal protein uL10 family.|||Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.|||Cytoplasm|||nucleolus http://togogenome.org/gene/508771:TGME49_293870 ^@ http://purl.uniprot.org/uniprot/A0A125YIY3 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/508771:TGME49_209820 ^@ http://purl.uniprot.org/uniprot/S8F8N8 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/508771:TGME49_260300 ^@ http://purl.uniprot.org/uniprot/S8GLQ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_294430 ^@ http://purl.uniprot.org/uniprot/S8GVA6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SDA1 family.|||Required for 60S pre-ribosomal subunits export to the cytoplasm.|||nucleolus http://togogenome.org/gene/508771:TGME49_247648 ^@ http://purl.uniprot.org/uniprot/A0A125YZM6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/508771:TGME49_239630 ^@ http://purl.uniprot.org/uniprot/S8F4Q6 ^@ Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Homodimer. http://togogenome.org/gene/508771:TGME49_310600 ^@ http://purl.uniprot.org/uniprot/A0A125YL57 ^@ Similarity ^@ Belongs to the HSBP1 family. http://togogenome.org/gene/508771:TGME49_277970 ^@ http://purl.uniprot.org/uniprot/S8GAL8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyltransferase 2 family.|||Component of the dolichol-phosphate mannose (DPM) synthase complex.|||Endoplasmic reticulum|||Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. http://togogenome.org/gene/508771:TGME49_315520 ^@ http://purl.uniprot.org/uniprot/A0A125YWB6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_217820 ^@ http://purl.uniprot.org/uniprot/A0A125YQV0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CSN7/EIF3M family. CSN7 subfamily.|||Belongs to the eIF-3 subunit M family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_207630 ^@ http://purl.uniprot.org/uniprot/A0A125YQX6 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/508771:TGME49_248760 ^@ http://purl.uniprot.org/uniprot/S8ERZ9 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/508771:TGME49_249900 ^@ http://purl.uniprot.org/uniprot/A0A125YLS6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/508771:TGME49_201700 ^@ http://purl.uniprot.org/uniprot/S8F6C0 ^@ Similarity ^@ Belongs to the WD repeat SEC13 family. http://togogenome.org/gene/508771:TGME49_211640 ^@ http://purl.uniprot.org/uniprot/S8GS54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/508771:TGME49_290840 ^@ http://purl.uniprot.org/uniprot/S8F082 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/508771:TGME49_310010 ^@ http://purl.uniprot.org/uniprot/A0A125YHF5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/508771:TGME49_278550 ^@ http://purl.uniprot.org/uniprot/S8EWB6 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. http://togogenome.org/gene/508771:TGME49_228300 ^@ http://purl.uniprot.org/uniprot/A0A125YV80 ^@ Similarity ^@ Belongs to the CCDC25 family. http://togogenome.org/gene/508771:TGME49_318560 ^@ http://purl.uniprot.org/uniprot/A0A125YPJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDK/BCKDK protein kinase family.|||Mitochondrion matrix http://togogenome.org/gene/508771:TGME49_200385 ^@ http://purl.uniprot.org/uniprot/S8GIB3 ^@ Developmental Stage|||Disruption Phenotype|||Function|||Induction|||Subcellular Location Annotation ^@ Expressed at a similar level during both the chronic and acute stages of infection (PubMed:31955846). However, transcripts are only translated during the chronic stage of infection, in response to stress conditions (PubMed:31955846).|||Master transcription factor that controls the differentiation of acute-stage tachyzoite parasites into chronic-stage bradyzoites, which form intracellular cysts resistant to immune clearance and existing therapies (PubMed:31955846). Sufficient to drive differentiation into bradyzoite stage (PubMed:31955846). Following translation in response to stress conditions, binds to the promoter of many chronic stage-specific genes and promotes their expression, thereby driving differentiation into bradyzoites (PubMed:31955846).|||Nucleus|||Parasites grow normally under standard conditions but fail to differentiate into chronic-stage bradyzoites under all induction conditions tested (PubMed:31955846). Parasites are unable to form brain cysts in mice (PubMed:31955846).|||Regulated at the translation level: while it is expressed during both the chronic and acute stages of infection, transcripts are only translated during the chronic stage of infection. http://togogenome.org/gene/508771:TGME49_256760 ^@ http://purl.uniprot.org/uniprot/A0A125YPV4 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/508771:TGME49_280600 ^@ http://purl.uniprot.org/uniprot/A0A125YMK6 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_240240 ^@ http://purl.uniprot.org/uniprot/S8F7K5 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/508771:TGME49_204050 ^@ http://purl.uniprot.org/uniprot/S8F5S3 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/508771:TGME49_315940 ^@ http://purl.uniprot.org/uniprot/S8EQK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lipase maturation factor family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_310280 ^@ http://purl.uniprot.org/uniprot/A0A125YYZ7 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/508771:TGME49_255260 ^@ http://purl.uniprot.org/uniprot/S8GKS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the apicomplexan parasites AMA1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_286800 ^@ http://purl.uniprot.org/uniprot/S8F595 ^@ Function|||Similarity ^@ Belongs to the MINDY deubiquitinase family. FAM188 subfamily.|||Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins. http://togogenome.org/gene/508771:TGME49_247380 ^@ http://purl.uniprot.org/uniprot/S8ERS6 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/508771:TGME49_314730 ^@ http://purl.uniprot.org/uniprot/S8ER60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ALG6/ALG8 glucosyltransferase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_270540 ^@ http://purl.uniprot.org/uniprot/A0A125YN13 ^@ Similarity ^@ Belongs to the TRM112 family. http://togogenome.org/gene/508771:TGME49_320690 ^@ http://purl.uniprot.org/uniprot/A0A125YXF8 ^@ Similarity ^@ Belongs to the SNAP family. http://togogenome.org/gene/508771:TGME49_318290 ^@ http://purl.uniprot.org/uniprot/A0A125YUZ4 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/508771:TGME49_222040 ^@ http://purl.uniprot.org/uniprot/S8GTY7 ^@ Similarity ^@ Belongs to the MOG1 family. http://togogenome.org/gene/508771:TGME49_309780 ^@ http://purl.uniprot.org/uniprot/S8ES67 ^@ Similarity ^@ Belongs to the RRP15 family. http://togogenome.org/gene/508771:TGME49_311030 ^@ http://purl.uniprot.org/uniprot/A0A125YY44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HEATR1/UTP10 family.|||Involved in nucleolar processing of pre-18S ribosomal RNA.|||nucleolus http://togogenome.org/gene/508771:TGME49_306900 ^@ http://purl.uniprot.org/uniprot/A0A125YV24 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/508771:TGME49_313530 ^@ http://purl.uniprot.org/uniprot/A0A125YSS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KISH family.|||Golgi apparatus membrane|||Involved in the early part of the secretory pathway.|||Membrane http://togogenome.org/gene/508771:TGME49_289830 ^@ http://purl.uniprot.org/uniprot/A0A125YIM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit I family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_215130 ^@ http://purl.uniprot.org/uniprot/S8EVV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cytoplasmic vesicle membrane|||Membrane http://togogenome.org/gene/508771:TGME49_253110 ^@ http://purl.uniprot.org/uniprot/S8GTF2 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_206310 ^@ http://purl.uniprot.org/uniprot/S8F5H4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Converts protoheme IX and farnesyl diphosphate to heme O.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/508771:TGME49_209620 ^@ http://purl.uniprot.org/uniprot/S8GKF9 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/508771:TGME49_238050 ^@ http://purl.uniprot.org/uniprot/A0A125YS68 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_258500 ^@ http://purl.uniprot.org/uniprot/S8F119 ^@ Similarity ^@ Belongs to the RRP7 family. http://togogenome.org/gene/508771:TGME49_219770 ^@ http://purl.uniprot.org/uniprot/S8EUD1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS12 family. http://togogenome.org/gene/508771:TGME49_269930 ^@ http://purl.uniprot.org/uniprot/S8GIS2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_305590 ^@ http://purl.uniprot.org/uniprot/A0A125YR82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_212990 ^@ http://purl.uniprot.org/uniprot/S8F8V6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CTL (choline transporter-like) family.|||Membrane http://togogenome.org/gene/508771:TGME49_229360 ^@ http://purl.uniprot.org/uniprot/S8F088 ^@ Similarity ^@ Belongs to the transaldolase family. Type 1 subfamily. http://togogenome.org/gene/508771:TGME49_248630 ^@ http://purl.uniprot.org/uniprot/A0A125YU22 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/508771:TGME49_209970 ^@ http://purl.uniprot.org/uniprot/S8F8M2 ^@ Similarity ^@ Belongs to the TUBGCP family. http://togogenome.org/gene/508771:TGME49_318720 ^@ http://purl.uniprot.org/uniprot/S8F9J8 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6. http://togogenome.org/gene/508771:TGME49_213870 ^@ http://purl.uniprot.org/uniprot/S8GRR9 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/508771:TGME49_218530 ^@ http://purl.uniprot.org/uniprot/S8FZM8 ^@ Similarity ^@ Belongs to the PITHD1 family. http://togogenome.org/gene/508771:TGME49_278830 ^@ http://purl.uniprot.org/uniprot/A0A125YW58 ^@ Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. http://togogenome.org/gene/508771:TGME49_281510 ^@ http://purl.uniprot.org/uniprot/S8F3K8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RNase HII family. Eukaryotic subfamily.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/508771:TGME49_277090 ^@ http://purl.uniprot.org/uniprot/A0A125YMI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_273460 ^@ http://purl.uniprot.org/uniprot/A0A125YVE4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit L family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_292000 ^@ http://purl.uniprot.org/uniprot/S8F3Q2 ^@ Similarity ^@ Belongs to the mTERF family. http://togogenome.org/gene/508771:TGME49_227952 ^@ http://purl.uniprot.org/uniprot/A0A125YQT1 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/508771:TGME49_313880 ^@ http://purl.uniprot.org/uniprot/A0A125YG64 ^@ Similarity ^@ Belongs to the CWC16 family. http://togogenome.org/gene/508771:TGME49_253530 ^@ http://purl.uniprot.org/uniprot/S8GTC2 ^@ Function|||Similarity ^@ Belongs to the eukaryotic/archaeal RNase P protein component 2 family.|||Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. http://togogenome.org/gene/508771:TGME49_275798 ^@ http://purl.uniprot.org/uniprot/S8GTN0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_225410 ^@ http://purl.uniprot.org/uniprot/S8EXE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H3 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_231600 ^@ http://purl.uniprot.org/uniprot/A0A125YHR2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_203870 ^@ http://purl.uniprot.org/uniprot/A0A125YPV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ISY1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_257090 ^@ http://purl.uniprot.org/uniprot/S8GBN3 ^@ Similarity|||Subunit ^@ Belongs to the NAC-beta family.|||Part of the nascent polypeptide-associated complex (NAC). http://togogenome.org/gene/508771:TGME49_215420 ^@ http://purl.uniprot.org/uniprot/A0A125YV39 ^@ Similarity ^@ Belongs to the synaptobrevin family. http://togogenome.org/gene/508771:TGME49_310950 ^@ http://purl.uniprot.org/uniprot/S8ERW4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_320670 ^@ http://purl.uniprot.org/uniprot/A0A125YWI2 ^@ Similarity ^@ Belongs to the VPS16 family. http://togogenome.org/gene/508771:TGME49_310870 ^@ http://purl.uniprot.org/uniprot/A0A125YMH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMCO1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_254120 ^@ http://purl.uniprot.org/uniprot/A0A125YKY6 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/508771:TGME49_249580 ^@ http://purl.uniprot.org/uniprot/A0A125YXL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_257000 ^@ http://purl.uniprot.org/uniprot/S8F0M6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_233190 ^@ http://purl.uniprot.org/uniprot/A0A125YK64 ^@ Similarity ^@ Belongs to the SNW family. http://togogenome.org/gene/508771:TGME49_218880 ^@ http://purl.uniprot.org/uniprot/A0A125YP87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF-assemblin family.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_318160 ^@ http://purl.uniprot.org/uniprot/A0A125YLG8 ^@ Similarity ^@ Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. http://togogenome.org/gene/508771:TGME49_271870 ^@ http://purl.uniprot.org/uniprot/S8G9U6 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/508771:TGME49_257530 ^@ http://purl.uniprot.org/uniprot/A0A125YHI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_297530 ^@ http://purl.uniprot.org/uniprot/S8F8D7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||apicoplast http://togogenome.org/gene/508771:TGME49_258740 ^@ http://purl.uniprot.org/uniprot/A0A125YPB8 ^@ Similarity ^@ Belongs to the WD repeat EIF2A family. http://togogenome.org/gene/508771:TGME49_222360 ^@ http://purl.uniprot.org/uniprot/S8GU11 ^@ Similarity ^@ Belongs to the UFL1 family. http://togogenome.org/gene/508771:TGME49_240280 ^@ http://purl.uniprot.org/uniprot/A0A125YMH3 ^@ Similarity ^@ Belongs to the nuclease type I family. http://togogenome.org/gene/508771:TGME49_308930 ^@ http://purl.uniprot.org/uniprot/A0A125YRM7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/508771:TGME49_297850 ^@ http://purl.uniprot.org/uniprot/A0A125YQ20 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/508771:TGME49_271820 ^@ http://purl.uniprot.org/uniprot/S8EYM8 ^@ Similarity ^@ Belongs to the LplA family. http://togogenome.org/gene/508771:TGME49_252320 ^@ http://purl.uniprot.org/uniprot/A0A125YVP1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the C1D family.|||Cytoplasm|||Monomer and homodimer.|||Nucleus|||Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.|||nucleolus http://togogenome.org/gene/508771:TGME49_223910 ^@ http://purl.uniprot.org/uniprot/A0A125YL01 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/508771:TGME49_313100 ^@ http://purl.uniprot.org/uniprot/A0A125YIZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_300140 ^@ http://purl.uniprot.org/uniprot/A0A125YG45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GST superfamily.|||EF-1 is composed of four subunits: alpha, beta, delta, and gamma.|||Probably plays a role in anchoring the complex to other cellular components. http://togogenome.org/gene/508771:TGME49_225260 ^@ http://purl.uniprot.org/uniprot/S8EXC5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Nucleus http://togogenome.org/gene/508771:TGME49_266070 ^@ http://purl.uniprot.org/uniprot/A0A125YYY3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL31 family. http://togogenome.org/gene/508771:TGME49_230840 ^@ http://purl.uniprot.org/uniprot/A0A125YXW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_271420 ^@ http://purl.uniprot.org/uniprot/S8EYK7 ^@ Similarity ^@ Belongs to the HMBS family. http://togogenome.org/gene/508771:TGME49_284170 ^@ http://purl.uniprot.org/uniprot/S8GQV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_201720 ^@ http://purl.uniprot.org/uniprot/S8GEP7 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/508771:TGME49_239752 ^@ http://purl.uniprot.org/uniprot/S8FAQ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_312200 ^@ http://purl.uniprot.org/uniprot/A0A125YH76 ^@ Similarity ^@ Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily. http://togogenome.org/gene/508771:TGME49_257020 ^@ http://purl.uniprot.org/uniprot/A0A125YKD4 ^@ Similarity ^@ Belongs to the TRAPPC13 family. http://togogenome.org/gene/508771:TGME49_264080 ^@ http://purl.uniprot.org/uniprot/A0A125YUR0 ^@ Function|||Similarity ^@ Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis. http://togogenome.org/gene/508771:TGME49_277530 ^@ http://purl.uniprot.org/uniprot/S8EWH4 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/508771:TGME49_258380 ^@ http://purl.uniprot.org/uniprot/S8GC03 ^@ Similarity ^@ Belongs to the elongation factor P family. http://togogenome.org/gene/508771:TGME49_229940 ^@ http://purl.uniprot.org/uniprot/A0A125YII8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SYF2 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_211910 ^@ http://purl.uniprot.org/uniprot/S8F054 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_271190 ^@ http://purl.uniprot.org/uniprot/S8F1J8 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. http://togogenome.org/gene/508771:TGME49_293220 ^@ http://purl.uniprot.org/uniprot/A0A125YN96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_227790 ^@ http://purl.uniprot.org/uniprot/S8F176 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.|||Membrane http://togogenome.org/gene/508771:TGME49_215170 ^@ http://purl.uniprot.org/uniprot/S8EST9 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/508771:TGME49_262000 ^@ http://purl.uniprot.org/uniprot/S8F1K6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_216130 ^@ http://purl.uniprot.org/uniprot/A0A125YWQ3 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/508771:TGME49_217450 ^@ http://purl.uniprot.org/uniprot/A0A125YS43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFB5 family.|||Component of the 7-subunit TFIIH core complex.|||In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.|||Nucleus http://togogenome.org/gene/508771:TGME49_309930 ^@ http://purl.uniprot.org/uniprot/S8G3P6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 27 family. http://togogenome.org/gene/508771:TGME49_254880 ^@ http://purl.uniprot.org/uniprot/S8FD94 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 27 family. http://togogenome.org/gene/508771:TGME49_286640 ^@ http://purl.uniprot.org/uniprot/S8FBH4 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. http://togogenome.org/gene/508771:TGME49_288900 ^@ http://purl.uniprot.org/uniprot/S8G838 ^@ Similarity ^@ Belongs to the YOS1 family. http://togogenome.org/gene/508771:TGME49_254610 ^@ http://purl.uniprot.org/uniprot/A0A125YM31 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/508771:TGME49_277850 ^@ http://purl.uniprot.org/uniprot/S8GAM6 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/508771:TGME49_216870 ^@ http://purl.uniprot.org/uniprot/A0A125YY42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family. RAD3/XPD subfamily.|||Nucleus http://togogenome.org/gene/508771:TGME49_244320 ^@ http://purl.uniprot.org/uniprot/S8GPP3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/508771:TGME49_220400 ^@ http://purl.uniprot.org/uniprot/S8GGZ6 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. http://togogenome.org/gene/508771:TGME49_243620 ^@ http://purl.uniprot.org/uniprot/S8F6Z8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_236210 ^@ http://purl.uniprot.org/uniprot/A0A125YS93 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/508771:TGME49_251930 ^@ http://purl.uniprot.org/uniprot/A0A125YZR0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/508771:TGME49_230980 ^@ http://purl.uniprot.org/uniprot/S8F673 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/508771:TGME49_300260 ^@ http://purl.uniprot.org/uniprot/S8EWL8 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_202630 ^@ http://purl.uniprot.org/uniprot/S8F993 ^@ Similarity ^@ In the C-terminal section; belongs to the peptidase M41 family.|||In the N-terminal section; belongs to the AAA ATPase family. http://togogenome.org/gene/508771:TGME49_203420 ^@ http://purl.uniprot.org/uniprot/S8F5Y4 ^@ Similarity ^@ Belongs to the endoribonuclease YbeY family. http://togogenome.org/gene/508771:TGME49_320110 ^@ http://purl.uniprot.org/uniprot/A0A125YZR9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PCNA family.|||Nucleus|||This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. http://togogenome.org/gene/508771:TGME49_285520 ^@ http://purl.uniprot.org/uniprot/S8F5J8 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family. http://togogenome.org/gene/508771:TGME49_212930 ^@ http://purl.uniprot.org/uniprot/S8GRH2 ^@ Similarity ^@ Belongs to the NifU family. http://togogenome.org/gene/508771:TGME49_202400 ^@ http://purl.uniprot.org/uniprot/S8F666 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_297780 ^@ http://purl.uniprot.org/uniprot/S8FEG4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase family.|||Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.|||Homodimer. http://togogenome.org/gene/508771:TGME49_225500 ^@ http://purl.uniprot.org/uniprot/S8F0Q9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_295710 ^@ http://purl.uniprot.org/uniprot/S8GV37 ^@ Similarity ^@ Belongs to the UPL family. TOM1/PTR1 subfamily. http://togogenome.org/gene/508771:TGME49_293260 ^@ http://purl.uniprot.org/uniprot/S8GLG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDK/BCKDK protein kinase family.|||Mitochondrion matrix http://togogenome.org/gene/508771:TGME49_295060 ^@ http://purl.uniprot.org/uniprot/A0A125YW06 ^@ Similarity ^@ Belongs to the exonuclease superfamily. TREX family. http://togogenome.org/gene/508771:TGME49_255460 ^@ http://purl.uniprot.org/uniprot/S8GKU6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_207080 ^@ http://purl.uniprot.org/uniprot/S8ESL0 ^@ Similarity ^@ Belongs to the MYST (SAS/MOZ) family. http://togogenome.org/gene/508771:TGME49_238110 ^@ http://purl.uniprot.org/uniprot/A0A125YM22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the replication factor A protein 3 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_245485 ^@ http://purl.uniprot.org/uniprot/S8ERA6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_246530 ^@ http://purl.uniprot.org/uniprot/S8G043 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-II family.|||Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_254280 ^@ http://purl.uniprot.org/uniprot/S8GIN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC9 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/508771:TGME49_261220 ^@ http://purl.uniprot.org/uniprot/A0A125YJM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPT4 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_263550 ^@ http://purl.uniprot.org/uniprot/A0A125YVS8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/508771:TGME49_309170 ^@ http://purl.uniprot.org/uniprot/A0A125YQR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF7 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_254010 ^@ http://purl.uniprot.org/uniprot/S8F7D5 ^@ Similarity ^@ Belongs to the peptidase S28 family. http://togogenome.org/gene/508771:TGME49_310000 ^@ http://purl.uniprot.org/uniprot/A0A125YM56 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_291040 ^@ http://purl.uniprot.org/uniprot/A0A125YPI5 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/508771:TGME49_202740 ^@ http://purl.uniprot.org/uniprot/S8GNQ5 ^@ Similarity ^@ Belongs to the pseudouridine synthase Pus10 family. http://togogenome.org/gene/508771:TGME49_283810 ^@ http://purl.uniprot.org/uniprot/S8GGI9 ^@ Similarity ^@ Belongs to the glycosyl hydrolases 36 family. http://togogenome.org/gene/508771:TGME49_214520 ^@ http://purl.uniprot.org/uniprot/S8G4F6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFB2 family.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.|||Nucleus http://togogenome.org/gene/508771:TGME49_249200 ^@ http://purl.uniprot.org/uniprot/A0A125YV52 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/508771:TGME49_237250 ^@ http://purl.uniprot.org/uniprot/S8EZI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/508771:TGME49_275490 ^@ http://purl.uniprot.org/uniprot/S8EZ80 ^@ Subcellular Location Annotation ^@ nuclear pore complex http://togogenome.org/gene/508771:TGME49_271030 ^@ http://purl.uniprot.org/uniprot/S8GIY9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_247930 ^@ http://purl.uniprot.org/uniprot/A0A125YUN6 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/508771:TGME49_260310 ^@ http://purl.uniprot.org/uniprot/A0A125YSH6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_200370 ^@ http://purl.uniprot.org/uniprot/S8EXJ7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the protein prenyltransferase subunit beta family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.|||Heterodimer of an alpha and a beta subunit. http://togogenome.org/gene/508771:TGME49_253380 ^@ http://purl.uniprot.org/uniprot/S8FDR0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_319740 ^@ http://purl.uniprot.org/uniprot/S8F6R5 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.|||Membrane http://togogenome.org/gene/508771:TGME49_218420 ^@ http://purl.uniprot.org/uniprot/S8G8T4 ^@ Similarity ^@ Belongs to the WD repeat PRL1/PRL2 family. http://togogenome.org/gene/508771:TGME49_203340 ^@ http://purl.uniprot.org/uniprot/S8GE66 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family. http://togogenome.org/gene/508771:TGME49_242320 ^@ http://purl.uniprot.org/uniprot/A0A125YZK2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_238010 ^@ http://purl.uniprot.org/uniprot/A0A125YU29 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL23 family. http://togogenome.org/gene/508771:TGME49_226000 ^@ http://purl.uniprot.org/uniprot/A0A125YRE3 ^@ Similarity ^@ Belongs to the ATPase epsilon chain family. http://togogenome.org/gene/508771:TGME49_289560 ^@ http://purl.uniprot.org/uniprot/A0A125YFB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM NCBP2 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_244480 ^@ http://purl.uniprot.org/uniprot/S8F438 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/508771:TGME49_272400 ^@ http://purl.uniprot.org/uniprot/A0A125YJS8 ^@ Similarity|||Subunit ^@ Belongs to the casein kinase 2 subunit beta family.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/508771:TGME49_304970 ^@ http://purl.uniprot.org/uniprot/A0A125YUD2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. http://togogenome.org/gene/508771:TGME49_214480 ^@ http://purl.uniprot.org/uniprot/S8GDN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the replication factor A protein 3 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_269582 ^@ http://purl.uniprot.org/uniprot/S8GIQ4 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/508771:TGME49_297840 ^@ http://purl.uniprot.org/uniprot/S8GUD1 ^@ Similarity ^@ Belongs to the eukaryotic-type primase large subunit family. http://togogenome.org/gene/508771:TGME49_213720 ^@ http://purl.uniprot.org/uniprot/S8F913 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DRC7 family.|||cilium axoneme|||flagellum http://togogenome.org/gene/508771:TGME49_201850 ^@ http://purl.uniprot.org/uniprot/S8GEM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat peroxin-7 family.|||Peroxisome matrix|||cytosol http://togogenome.org/gene/508771:TGME49_261630 ^@ http://purl.uniprot.org/uniprot/S8F4H6 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/508771:TGME49_260260 ^@ http://purl.uniprot.org/uniprot/A0A125YWZ2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family. http://togogenome.org/gene/508771:TGME49_217570 ^@ http://purl.uniprot.org/uniprot/S8EN92 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS27 family. http://togogenome.org/gene/508771:TGME49_256990 ^@ http://purl.uniprot.org/uniprot/S8GBM3 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_225125 ^@ http://purl.uniprot.org/uniprot/S8GF05 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/508771:TGME49_260850 ^@ http://purl.uniprot.org/uniprot/S8GLV2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/508771:TGME49_220150 ^@ http://purl.uniprot.org/uniprot/A0A125YNI9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/508771:TGME49_294330 ^@ http://purl.uniprot.org/uniprot/A0A125YRE5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_310900 ^@ http://purl.uniprot.org/uniprot/A0A125YJB8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_320730 ^@ http://purl.uniprot.org/uniprot/A0A125YQB9 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. MetX family. http://togogenome.org/gene/508771:TGME49_283720 ^@ http://purl.uniprot.org/uniprot/S8GQX3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PTPA-type PPIase family.|||Cytoplasm|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/508771:TGME49_247470 ^@ http://purl.uniprot.org/uniprot/A0A125YGZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP5/NOP56 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_278490 ^@ http://purl.uniprot.org/uniprot/A0A125YVE3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_288630 ^@ http://purl.uniprot.org/uniprot/A0A125YGQ7 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/508771:TGME49_301390 ^@ http://purl.uniprot.org/uniprot/A0A125YLE8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat BOP1/ERB1 family.|||Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.|||nucleolus|||nucleoplasm http://togogenome.org/gene/508771:TGME49_316900 ^@ http://purl.uniprot.org/uniprot/S8EQE2 ^@ Similarity ^@ Belongs to the SAS10 family. http://togogenome.org/gene/508771:TGME49_265120 ^@ http://purl.uniprot.org/uniprot/B6KLP1 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the apicomplexan parasites RON2 family.|||Host cell membrane|||May play a role in host cell invasion.|||Readily detected in oocysts (at protein level). Specifically up-regulated in sporozoites, but not in tachyzoites and bradyzoites.|||Secreted http://togogenome.org/gene/508771:TGME49_294850 ^@ http://purl.uniprot.org/uniprot/S8FCD7 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/508771:TGME49_239480 ^@ http://purl.uniprot.org/uniprot/S8F4S1 ^@ Similarity ^@ Belongs to the RNR ribonuclease family. http://togogenome.org/gene/508771:TGME49_275690 ^@ http://purl.uniprot.org/uniprot/S8FDW1 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/508771:TGME49_309810 ^@ http://purl.uniprot.org/uniprot/A0A125YFT4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family. http://togogenome.org/gene/508771:TGME49_320220 ^@ http://purl.uniprot.org/uniprot/A0A125YZC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Membrane http://togogenome.org/gene/508771:TGME49_205625 ^@ http://purl.uniprot.org/uniprot/S8F2I6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_253700 ^@ http://purl.uniprot.org/uniprot/S8GIV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/508771:TGME49_249770 ^@ http://purl.uniprot.org/uniprot/A0A125YXX7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/508771:TGME49_304650 ^@ http://purl.uniprot.org/uniprot/A0A125YXC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histidine acid phosphatase family. VIP1 subfamily.|||cytosol http://togogenome.org/gene/508771:TGME49_216070 ^@ http://purl.uniprot.org/uniprot/A0A125YIN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/508771:TGME49_204360 ^@ http://purl.uniprot.org/uniprot/S8F8Y0 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/508771:TGME49_281630 ^@ http://purl.uniprot.org/uniprot/S8GP63 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. http://togogenome.org/gene/508771:TGME49_305460 ^@ http://purl.uniprot.org/uniprot/A0A125YP69 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).|||Cytoplasm http://togogenome.org/gene/508771:TGME49_203700 ^@ http://purl.uniprot.org/uniprot/A0A125YYM2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/508771:TGME49_311690 ^@ http://purl.uniprot.org/uniprot/S8GCG0 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/508771:TGME49_305060 ^@ http://purl.uniprot.org/uniprot/A0A125YFI7 ^@ Similarity ^@ Belongs to the TBCB family. http://togogenome.org/gene/508771:TGME49_292330 ^@ http://purl.uniprot.org/uniprot/S8F3T4 ^@ Similarity ^@ Belongs to the TMEM121 family. http://togogenome.org/gene/508771:TGME49_221260 ^@ http://purl.uniprot.org/uniprot/S8F7V5 ^@ Cofactor|||Similarity ^@ Belongs to the class-II DAHP synthase family.|||Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions. http://togogenome.org/gene/508771:TGME49_236780 ^@ http://purl.uniprot.org/uniprot/S8G4R3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_300190 ^@ http://purl.uniprot.org/uniprot/A0A125YTT4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL43 family. http://togogenome.org/gene/508771:TGME49_233065 ^@ http://purl.uniprot.org/uniprot/S8GK07 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_213840 ^@ http://purl.uniprot.org/uniprot/S8F5Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CTL (choline transporter-like) family.|||Membrane http://togogenome.org/gene/508771:TGME49_233010 ^@ http://purl.uniprot.org/uniprot/S8GK09 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/508771:TGME49_244270 ^@ http://purl.uniprot.org/uniprot/A0A125YJE3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_208990 ^@ http://purl.uniprot.org/uniprot/A0A125YNM4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_205650 ^@ http://purl.uniprot.org/uniprot/S8F8R5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_221580 ^@ http://purl.uniprot.org/uniprot/S8FB13 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1). http://togogenome.org/gene/508771:TGME49_214780 ^@ http://purl.uniprot.org/uniprot/S8EVY1 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/508771:TGME49_271610 ^@ http://purl.uniprot.org/uniprot/S8EYL8 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/508771:TGME49_295000 ^@ http://purl.uniprot.org/uniprot/A0A125YMM9 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/508771:TGME49_216800 ^@ http://purl.uniprot.org/uniprot/A0A125YFR6 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May be involved in spermatogenesis.|||Nucleus http://togogenome.org/gene/508771:TGME49_259020 ^@ http://purl.uniprot.org/uniprot/A0A125YNI2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/508771:TGME49_214850 ^@ http://purl.uniprot.org/uniprot/S8ESX0 ^@ Similarity ^@ Belongs to the DXR family. http://togogenome.org/gene/508771:TGME49_217620 ^@ http://purl.uniprot.org/uniprot/A0A125YGC8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/508771:TGME49_273850 ^@ http://purl.uniprot.org/uniprot/S8EZ04 ^@ Similarity ^@ Belongs to the nucleoporin NSP1/NUP62 family. http://togogenome.org/gene/508771:TGME49_230050 ^@ http://purl.uniprot.org/uniprot/A0A125YKW9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/508771:TGME49_319920 ^@ http://purl.uniprot.org/uniprot/A0A125YJJ9 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/508771:TGME49_309290 ^@ http://purl.uniprot.org/uniprot/A0A125YPB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HDDC2 family.|||Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).|||Homodimer. http://togogenome.org/gene/508771:TGME49_280760 ^@ http://purl.uniprot.org/uniprot/A0A125YLJ9 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/508771:TGME49_265542 ^@ http://purl.uniprot.org/uniprot/S8F2G5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Enzyme with a broad specificity.|||Membrane http://togogenome.org/gene/508771:TGME49_245620 ^@ http://purl.uniprot.org/uniprot/A0A125YIT7 ^@ Similarity ^@ In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.|||In the N-terminal section; belongs to the ubiquitin family. http://togogenome.org/gene/508771:TGME49_273970 ^@ http://purl.uniprot.org/uniprot/A0A125YGS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_202540 ^@ http://purl.uniprot.org/uniprot/S8F656 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_247250 ^@ http://purl.uniprot.org/uniprot/A0A125YMQ5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_210690 ^@ http://purl.uniprot.org/uniprot/A0A125YZ11 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/508771:TGME49_212130 ^@ http://purl.uniprot.org/uniprot/S8EWW8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_258650 ^@ http://purl.uniprot.org/uniprot/S8GLF8 ^@ Similarity ^@ Belongs to the ferrochelatase family. http://togogenome.org/gene/508771:TGME49_270800 ^@ http://purl.uniprot.org/uniprot/S8GIX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_217890 ^@ http://purl.uniprot.org/uniprot/A0A125YNG8 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/508771:TGME49_242350 ^@ http://purl.uniprot.org/uniprot/A0A125YG26 ^@ Similarity ^@ Belongs to the TTC21 family. http://togogenome.org/gene/508771:TGME49_236030 ^@ http://purl.uniprot.org/uniprot/S8G4W2 ^@ Similarity ^@ Belongs to the OPI10 family. http://togogenome.org/gene/508771:TGME49_210960 ^@ http://purl.uniprot.org/uniprot/A0A125YWJ7 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/508771:TGME49_271210 ^@ http://purl.uniprot.org/uniprot/S8GJ05 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/508771:TGME49_239760 ^@ http://purl.uniprot.org/uniprot/A0A125YT46 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/508771:TGME49_254380 ^@ http://purl.uniprot.org/uniprot/A0A125YTN1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/508771:TGME49_293800 ^@ http://purl.uniprot.org/uniprot/A0A125YIR2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_242330 ^@ http://purl.uniprot.org/uniprot/A0A125YNF9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS7 family. http://togogenome.org/gene/508771:TGME49_278990 ^@ http://purl.uniprot.org/uniprot/A0A125YTR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_289750 ^@ http://purl.uniprot.org/uniprot/A0A125YNY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Component of the 60S subunit of the ribosome.|||Cytoplasm|||In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.|||In the N-terminal section; belongs to the ubiquitin family.|||Nucleus|||Part of the 60S ribosomal subunit. http://togogenome.org/gene/508771:TGME49_235620 ^@ http://purl.uniprot.org/uniprot/A0A125YU47 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/508771:TGME49_221522 ^@ http://purl.uniprot.org/uniprot/S8F7Y2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. http://togogenome.org/gene/508771:TGME49_278518 ^@ http://purl.uniprot.org/uniprot/S8EST3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Membrane http://togogenome.org/gene/508771:TGME49_226600 ^@ http://purl.uniprot.org/uniprot/A0A125YTW0 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/508771:TGME49_209280 ^@ http://purl.uniprot.org/uniprot/S8FEX8 ^@ Similarity ^@ Belongs to the FAM76 family. http://togogenome.org/gene/508771:TGME49_257390 ^@ http://purl.uniprot.org/uniprot/S8F6X6 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. http://togogenome.org/gene/508771:TGME49_233720 ^@ http://purl.uniprot.org/uniprot/A0A125YZK9 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RPB8 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/508771:TGME49_229490 ^@ http://purl.uniprot.org/uniprot/S8GB91 ^@ Similarity ^@ Belongs to the TTC9 family. http://togogenome.org/gene/508771:TGME49_203350 ^@ http://purl.uniprot.org/uniprot/S8GNI5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_234570 ^@ http://purl.uniprot.org/uniprot/A0A125YZ46 ^@ Subcellular Location Annotation ^@ Peroxisome http://togogenome.org/gene/508771:TGME49_216240 ^@ http://purl.uniprot.org/uniprot/S8G1T0 ^@ Similarity ^@ Belongs to the TBCC family. http://togogenome.org/gene/508771:TGME49_203300 ^@ http://purl.uniprot.org/uniprot/S8GNJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMCO4 family.|||Membrane http://togogenome.org/gene/508771:TGME49_264820 ^@ http://purl.uniprot.org/uniprot/S8G7S1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_316400 ^@ http://purl.uniprot.org/uniprot/A0A125YQG0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/508771:TGME49_292080 ^@ http://purl.uniprot.org/uniprot/S8GI40 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_275980 ^@ http://purl.uniprot.org/uniprot/S8FDX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COQ4 family.|||Component of a multi-subunit COQ enzyme complex.|||Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_207820 ^@ http://purl.uniprot.org/uniprot/A0A125YQE4 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/508771:TGME49_252340 ^@ http://purl.uniprot.org/uniprot/S8FDU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_251670 ^@ http://purl.uniprot.org/uniprot/A0A125YS30 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/508771:TGME49_266060 ^@ http://purl.uniprot.org/uniprot/A0A125YJG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the universal ribosomal protein uS2 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21.|||Cytoplasm|||Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. http://togogenome.org/gene/508771:TGME49_309740 ^@ http://purl.uniprot.org/uniprot/A0A125YS35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/508771:TGME49_315845 ^@ http://purl.uniprot.org/uniprot/S8EX78 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_202820 ^@ http://purl.uniprot.org/uniprot/A0A125YRV8 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/508771:TGME49_213670 ^@ http://purl.uniprot.org/uniprot/S8F910 ^@ Similarity ^@ Belongs to the MICOS complex subunit Mic60 family. http://togogenome.org/gene/508771:TGME49_249530 ^@ http://purl.uniprot.org/uniprot/S8G0P0 ^@ Similarity ^@ Belongs to the exportin family. http://togogenome.org/gene/508771:TGME49_314270 ^@ http://purl.uniprot.org/uniprot/S8EXS1 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/508771:TGME49_204040 ^@ http://purl.uniprot.org/uniprot/S8GNC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A22A family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_220930 ^@ http://purl.uniprot.org/uniprot/S8FAW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CTL (choline transporter-like) family.|||Cell membrane|||Choline transporter.|||Membrane http://togogenome.org/gene/508771:TGME49_297080 ^@ http://purl.uniprot.org/uniprot/S8FEB3 ^@ Similarity ^@ Belongs to the pyridoxine kinase family. http://togogenome.org/gene/508771:TGME49_235020 ^@ http://purl.uniprot.org/uniprot/S8GEA9 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane|||Membrane http://togogenome.org/gene/508771:TGME49_244700 ^@ http://purl.uniprot.org/uniprot/S8GFH2 ^@ Similarity ^@ Belongs to the NAD kinase family. http://togogenome.org/gene/508771:TGME49_221310 ^@ http://purl.uniprot.org/uniprot/S8FAY3 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/508771:TGME49_239320 ^@ http://purl.uniprot.org/uniprot/A0A125YKY3 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/508771:TGME49_313140 ^@ http://purl.uniprot.org/uniprot/S8EUA8 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/508771:TGME49_224880 ^@ http://purl.uniprot.org/uniprot/S8EX90 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_291670 ^@ http://purl.uniprot.org/uniprot/A0A125YM03 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/508771:TGME49_272280 ^@ http://purl.uniprot.org/uniprot/S8GJ93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Enzyme with a broad specificity.|||Membrane http://togogenome.org/gene/508771:TGME49_313130 ^@ http://purl.uniprot.org/uniprot/A0A125YJC1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP14 family.|||Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.|||nucleolus http://togogenome.org/gene/508771:TGME49_209030 ^@ http://purl.uniprot.org/uniprot/A0A125YH18 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/508771:TGME49_232390 ^@ http://purl.uniprot.org/uniprot/A0A125YMK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.|||nucleolus http://togogenome.org/gene/508771:TGME49_216900 ^@ http://purl.uniprot.org/uniprot/S8EWZ2 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anamorsin family.|||Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mitochondrion intermembrane space|||Monomer.|||The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.|||The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.|||The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space. http://togogenome.org/gene/508771:TGME49_262960 ^@ http://purl.uniprot.org/uniprot/A0A125YN00 ^@ Similarity ^@ Belongs to the Luc7 family. http://togogenome.org/gene/508771:TGME49_218770 ^@ http://purl.uniprot.org/uniprot/S8EQX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_269120 ^@ http://purl.uniprot.org/uniprot/S8F157 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/508771:TGME49_265330 ^@ http://purl.uniprot.org/uniprot/A0A125YY77 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. http://togogenome.org/gene/508771:TGME49_208560 ^@ http://purl.uniprot.org/uniprot/S8FC35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_219620 ^@ http://purl.uniprot.org/uniprot/S8FZE3 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/508771:TGME49_310100 ^@ http://purl.uniprot.org/uniprot/A0A125YTS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGM family.|||Endoplasmic reticulum membrane|||Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.|||Membrane http://togogenome.org/gene/508771:TGME49_208580 ^@ http://purl.uniprot.org/uniprot/S8GKM6 ^@ Similarity ^@ Belongs to the ATP-dependent DNA ligase family. http://togogenome.org/gene/508771:TGME49_262540 ^@ http://purl.uniprot.org/uniprot/S8F1N2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/508771:TGME49_216700 ^@ http://purl.uniprot.org/uniprot/S8ETE4 ^@ Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. http://togogenome.org/gene/508771:TGME49_254400 ^@ http://purl.uniprot.org/uniprot/S8F793 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/508771:TGME49_313150 ^@ http://purl.uniprot.org/uniprot/A0A125YWD2 ^@ Domain|||Function|||Similarity ^@ Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.|||Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.|||Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine. http://togogenome.org/gene/508771:TGME49_227960 ^@ http://purl.uniprot.org/uniprot/S8EXX5 ^@ Similarity ^@ Belongs to the proteasome subunit S9 family. http://togogenome.org/gene/508771:TGME49_294640 ^@ http://purl.uniprot.org/uniprot/A0A125YNJ1 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/508771:TGME49_232350 ^@ http://purl.uniprot.org/uniprot/A0A125YWC9 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/508771:TGME49_219650 ^@ http://purl.uniprot.org/uniprot/S8EQU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/508771:TGME49_232590 ^@ http://purl.uniprot.org/uniprot/A0A125YWW8 ^@ Similarity ^@ Belongs to the glutamate--cysteine ligase type 3 family. http://togogenome.org/gene/508771:TGME49_237570 ^@ http://purl.uniprot.org/uniprot/S8GDT0 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. LCMT family. http://togogenome.org/gene/508771:TGME49_258110 ^@ http://purl.uniprot.org/uniprot/S8F741 ^@ Function|||Similarity ^@ Belongs to the PIGL family.|||Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol. http://togogenome.org/gene/508771:TGME49_266910 ^@ http://purl.uniprot.org/uniprot/S8GGN1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_257960 ^@ http://purl.uniprot.org/uniprot/A0A125YY04 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/508771:TGME49_292310 ^@ http://purl.uniprot.org/uniprot/S8GI59 ^@ Similarity ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family. http://togogenome.org/gene/508771:TGME49_248950 ^@ http://purl.uniprot.org/uniprot/S8EVK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_281580 ^@ http://purl.uniprot.org/uniprot/S8GP58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Enzyme with a broad specificity.|||Membrane http://togogenome.org/gene/508771:TGME49_294320 ^@ http://purl.uniprot.org/uniprot/A0A125YW89 ^@ Similarity ^@ Belongs to the OSBP family. http://togogenome.org/gene/508771:TGME49_294200 ^@ http://purl.uniprot.org/uniprot/A0A125YWK7 ^@ Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. http://togogenome.org/gene/508771:TGME49_267800 ^@ http://purl.uniprot.org/uniprot/S8EYU3 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. http://togogenome.org/gene/508771:TGME49_318410 ^@ http://purl.uniprot.org/uniprot/A0A125YLR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_310520 ^@ http://purl.uniprot.org/uniprot/S8ERZ4 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_228250 ^@ http://purl.uniprot.org/uniprot/S8GFW2 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. http://togogenome.org/gene/508771:TGME49_209800 ^@ http://purl.uniprot.org/uniprot/A0A125YSC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/508771:TGME49_242230 ^@ http://purl.uniprot.org/uniprot/S8GP91 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_313350 ^@ http://purl.uniprot.org/uniprot/A0A125YN87 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_244390 ^@ http://purl.uniprot.org/uniprot/A0A125YNK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COPE family.|||Membrane http://togogenome.org/gene/508771:TGME49_247360 ^@ http://purl.uniprot.org/uniprot/A0A125YJ70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/508771:TGME49_205440 ^@ http://purl.uniprot.org/uniprot/S8GDS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_242720 ^@ http://purl.uniprot.org/uniprot/S8F6T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_264690 ^@ http://purl.uniprot.org/uniprot/S8GH68 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/508771:TGME49_313230 ^@ http://purl.uniprot.org/uniprot/A0A125YGI3 ^@ Similarity ^@ Belongs to the eIF-2-alpha family. http://togogenome.org/gene/508771:TGME49_258160 ^@ http://purl.uniprot.org/uniprot/A0A125YP68 ^@ Function|||Similarity ^@ Belongs to the NnrD/CARKD family.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. http://togogenome.org/gene/508771:TGME49_279390 ^@ http://purl.uniprot.org/uniprot/S8GGC0 ^@ Similarity ^@ Belongs to the peptidase M24 family. http://togogenome.org/gene/508771:TGME49_228330 ^@ http://purl.uniprot.org/uniprot/S8EV78 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_277720 ^@ http://purl.uniprot.org/uniprot/A0A125YGF2 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/508771:TGME49_293630 ^@ http://purl.uniprot.org/uniprot/A0A125YPX6 ^@ Similarity ^@ Belongs to the ARS2 family. http://togogenome.org/gene/508771:TGME49_221360 ^@ http://purl.uniprot.org/uniprot/S8FAY8 ^@ Similarity ^@ Belongs to the beclin family. http://togogenome.org/gene/508771:TGME49_221330 ^@ http://purl.uniprot.org/uniprot/S8GTS7 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/508771:TGME49_318310 ^@ http://purl.uniprot.org/uniprot/S8F9G6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/508771:TGME49_315600 ^@ http://purl.uniprot.org/uniprot/S8GBL9 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/508771:TGME49_213550 ^@ http://purl.uniprot.org/uniprot/S8F5W6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_209190 ^@ http://purl.uniprot.org/uniprot/A0A125YYJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_257030 ^@ http://purl.uniprot.org/uniprot/S8GL28 ^@ Similarity ^@ Belongs to the HPF1 family. http://togogenome.org/gene/508771:TGME49_267490 ^@ http://purl.uniprot.org/uniprot/A0A125YVZ5 ^@ Similarity|||Subunit ^@ Belongs to the peptidase C1 family.|||Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains. http://togogenome.org/gene/508771:TGME49_262450 ^@ http://purl.uniprot.org/uniprot/S8F4M5 ^@ Similarity ^@ Belongs to the dymeclin family. http://togogenome.org/gene/508771:TGME49_236650 ^@ http://purl.uniprot.org/uniprot/S8EZK1 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/508771:TGME49_269700 ^@ http://purl.uniprot.org/uniprot/S8GIR0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_217560 ^@ http://purl.uniprot.org/uniprot/A0A125YU83 ^@ Similarity ^@ Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family. http://togogenome.org/gene/508771:TGME49_221700 ^@ http://purl.uniprot.org/uniprot/A0A125YGT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP23 family.|||Membrane http://togogenome.org/gene/508771:TGME49_267400 ^@ http://purl.uniprot.org/uniprot/A0A125YTP4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/508771:TGME49_293230 ^@ http://purl.uniprot.org/uniprot/A0A125YK91 ^@ Similarity ^@ Belongs to the FAM98 family. http://togogenome.org/gene/508771:TGME49_285200 ^@ http://purl.uniprot.org/uniprot/S8GGE9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_234450 ^@ http://purl.uniprot.org/uniprot/A0A125YJX2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS8 family. http://togogenome.org/gene/508771:TGME49_231110 ^@ http://purl.uniprot.org/uniprot/A0A125YL33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_223000 ^@ http://purl.uniprot.org/uniprot/A0A125YL67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_257040 ^@ http://purl.uniprot.org/uniprot/A0A125YT51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_219440 ^@ http://purl.uniprot.org/uniprot/S8FZG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.|||Nucleus http://togogenome.org/gene/508771:TGME49_262710 ^@ http://purl.uniprot.org/uniprot/S8F7Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Membrane http://togogenome.org/gene/508771:TGME49_310430 ^@ http://purl.uniprot.org/uniprot/S8EUY3 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/508771:TGME49_219290 ^@ http://purl.uniprot.org/uniprot/S8EN02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the F-actin-capping protein beta subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_313060 ^@ http://purl.uniprot.org/uniprot/S8G2Y0 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/508771:TGME49_208590 ^@ http://purl.uniprot.org/uniprot/A0A125YWH0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase H subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/508771:TGME49_262760 ^@ http://purl.uniprot.org/uniprot/S8GM99 ^@ Similarity ^@ Belongs to the poly(ADP-ribose) glycohydrolase family. http://togogenome.org/gene/508771:TGME49_234280 ^@ http://purl.uniprot.org/uniprot/S8F041 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/508771:TGME49_235750 ^@ http://purl.uniprot.org/uniprot/A0A125YXB2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_205410 ^@ http://purl.uniprot.org/uniprot/S8GN37 ^@ Similarity ^@ Belongs to the pseudouridine synthase RluA family. http://togogenome.org/gene/508771:TGME49_268860 ^@ http://purl.uniprot.org/uniprot/A0A125YK06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_312622 ^@ http://purl.uniprot.org/uniprot/S8EUE6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_259530 ^@ http://purl.uniprot.org/uniprot/A0A125YXQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Membrane http://togogenome.org/gene/508771:TGME49_293480 ^@ http://purl.uniprot.org/uniprot/A0A125YLI8 ^@ Similarity ^@ In the C-terminal section; belongs to the MoeA family. http://togogenome.org/gene/508771:TGME49_230060 ^@ http://purl.uniprot.org/uniprot/A0A125YH14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. NAA40 subfamily.|||Cytoplasm|||Nucleus http://togogenome.org/gene/508771:TGME49_202880 ^@ http://purl.uniprot.org/uniprot/S8GEB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_305560 ^@ http://purl.uniprot.org/uniprot/A0A125YZF6 ^@ Similarity ^@ Belongs to the VPS51 family. http://togogenome.org/gene/508771:TGME49_244880 ^@ http://purl.uniprot.org/uniprot/S8F472 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/508771:TGME49_300040 ^@ http://purl.uniprot.org/uniprot/A0A125YU10 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/508771:TGME49_267680 ^@ http://purl.uniprot.org/uniprot/S8GGF0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_310700 ^@ http://purl.uniprot.org/uniprot/A0A125YY13 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/508771:TGME49_309210 ^@ http://purl.uniprot.org/uniprot/S8G3X4 ^@ Similarity ^@ Belongs to the peroxiredoxin family. Prx6 subfamily. http://togogenome.org/gene/508771:TGME49_208050 ^@ http://purl.uniprot.org/uniprot/S8GUX0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_228180 ^@ http://purl.uniprot.org/uniprot/A0A125YL26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX15/CtaA family.|||Membrane http://togogenome.org/gene/508771:TGME49_293300 ^@ http://purl.uniprot.org/uniprot/A0A125YH22 ^@ Similarity ^@ Belongs to the YIP1 family. http://togogenome.org/gene/508771:TGME49_291010 ^@ http://purl.uniprot.org/uniprot/S8F0A7 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/508771:TGME49_270850 ^@ http://purl.uniprot.org/uniprot/S8G9M7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 17 family. http://togogenome.org/gene/508771:TGME49_244620 ^@ http://purl.uniprot.org/uniprot/S8F454 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_265500 ^@ http://purl.uniprot.org/uniprot/S8F2G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel (TC 2.A.49) family.|||Membrane http://togogenome.org/gene/508771:TGME49_294690 ^@ http://purl.uniprot.org/uniprot/A0A125YG69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_313410 ^@ http://purl.uniprot.org/uniprot/S8ERE3 ^@ Similarity ^@ Belongs to the proteasome subunit S2 family. http://togogenome.org/gene/508771:TGME49_297760 ^@ http://purl.uniprot.org/uniprot/S8F8F0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLX9 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_212910 ^@ http://purl.uniprot.org/uniprot/S8F8U9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_227260 ^@ http://purl.uniprot.org/uniprot/S8GFK2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/508771:TGME49_200430 ^@ http://purl.uniprot.org/uniprot/S8EXJ3 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/508771:TGME49_223530 ^@ http://purl.uniprot.org/uniprot/A0A125YZA2 ^@ Similarity ^@ Belongs to the MOZART1 family. http://togogenome.org/gene/508771:TGME49_268600 ^@ http://purl.uniprot.org/uniprot/S8F0V4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase alpha subunit B family.|||Nucleus http://togogenome.org/gene/508771:TGME49_228370 ^@ http://purl.uniprot.org/uniprot/S8G6K8 ^@ Similarity ^@ Belongs to the nuclease type I family. http://togogenome.org/gene/508771:TGME49_257990 ^@ http://purl.uniprot.org/uniprot/S8GLC5 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/508771:TGME49_270210 ^@ http://purl.uniprot.org/uniprot/S8G9I3 ^@ Caution|||Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_295658 ^@ http://purl.uniprot.org/uniprot/S8GV32 ^@ Function|||Similarity ^@ Belongs to the UBR1 family.|||Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. http://togogenome.org/gene/508771:TGME49_276170 ^@ http://purl.uniprot.org/uniprot/S8F7T2 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily. http://togogenome.org/gene/508771:TGME49_207600 ^@ http://purl.uniprot.org/uniprot/S8F962 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tubulin family.|||Nucleus|||centriole|||cilium http://togogenome.org/gene/508771:TGME49_318180 ^@ http://purl.uniprot.org/uniprot/A0A125YWK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxin-16 family.|||Peroxisome membrane http://togogenome.org/gene/508771:TGME49_224590 ^@ http://purl.uniprot.org/uniprot/S8F0G5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.|||Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.|||Nucleus http://togogenome.org/gene/508771:TGME49_261010 ^@ http://purl.uniprot.org/uniprot/A0A125YT33 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/508771:TGME49_208710 ^@ http://purl.uniprot.org/uniprot/S8FF13 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/508771:TGME49_286560 ^@ http://purl.uniprot.org/uniprot/A0A125YNH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/508771:TGME49_305140 ^@ http://purl.uniprot.org/uniprot/A0A125YU24 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_256780 ^@ http://purl.uniprot.org/uniprot/S8GBK5 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/508771:TGME49_269250 ^@ http://purl.uniprot.org/uniprot/A0A125YH12 ^@ Similarity ^@ Belongs to the peptidase M67A family. http://togogenome.org/gene/508771:TGME49_289350 ^@ http://purl.uniprot.org/uniprot/A0A125YI39 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_305220 ^@ http://purl.uniprot.org/uniprot/S8GG15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AMY1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_281980 ^@ http://purl.uniprot.org/uniprot/S8F6P0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/508771:TGME49_265440 ^@ http://purl.uniprot.org/uniprot/S8GGY0 ^@ Similarity ^@ Belongs to the PPP4R2 family. http://togogenome.org/gene/508771:TGME49_314418 ^@ http://purl.uniprot.org/uniprot/A0A125YX13 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/508771:TGME49_254180 ^@ http://purl.uniprot.org/uniprot/S8GIQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the flagellar radial spoke RSP3 family.|||flagellum axoneme http://togogenome.org/gene/508771:TGME49_249370 ^@ http://purl.uniprot.org/uniprot/S8EP13 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/508771:TGME49_253800 ^@ http://purl.uniprot.org/uniprot/S8GIU7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/508771:TGME49_321660 ^@ http://purl.uniprot.org/uniprot/S8FBL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 22 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_313470 ^@ http://purl.uniprot.org/uniprot/S8EXW5 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/508771:TGME49_286220 ^@ http://purl.uniprot.org/uniprot/S8F5E1 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily. http://togogenome.org/gene/508771:TGME49_204160 ^@ http://purl.uniprot.org/uniprot/S8GDZ2 ^@ Similarity ^@ Belongs to the WD repeat EIF2A family. http://togogenome.org/gene/508771:TGME49_320270 ^@ http://purl.uniprot.org/uniprot/A0A125YQK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/508771:TGME49_237150 ^@ http://purl.uniprot.org/uniprot/S8GDV7 ^@ Similarity ^@ Belongs to the peptidase A22B family. http://togogenome.org/gene/508771:TGME49_290730 ^@ http://purl.uniprot.org/uniprot/S8G8H6 ^@ Similarity ^@ Belongs to the p23/wos2 family. http://togogenome.org/gene/508771:TGME49_212150 ^@ http://purl.uniprot.org/uniprot/S8G5D3 ^@ Similarity ^@ Belongs to the COG4 family. http://togogenome.org/gene/508771:TGME49_321300 ^@ http://purl.uniprot.org/uniprot/S8GK31 ^@ Similarity|||Subunit ^@ Belongs to the ATG12 family.|||Forms a conjugate with ATG5. http://togogenome.org/gene/508771:TGME49_211870 ^@ http://purl.uniprot.org/uniprot/S8G5C3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL18 family. http://togogenome.org/gene/508771:TGME49_285160 ^@ http://purl.uniprot.org/uniprot/S8GQT1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_203260 ^@ http://purl.uniprot.org/uniprot/S8F948 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad17/RAD24 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_269035 ^@ http://purl.uniprot.org/uniprot/S8G989 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/508771:TGME49_263500 ^@ http://purl.uniprot.org/uniprot/S8F892 ^@ Similarity ^@ Belongs to the VPS26 family. http://togogenome.org/gene/508771:TGME49_247460 ^@ http://purl.uniprot.org/uniprot/A0A125YTT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PCNA family.|||Nucleus|||This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. http://togogenome.org/gene/508771:TGME49_249620 ^@ http://purl.uniprot.org/uniprot/S8EP32 ^@ Similarity ^@ Belongs to the histone deacetylase family. HD type 1 subfamily. http://togogenome.org/gene/508771:TGME49_262920 ^@ http://purl.uniprot.org/uniprot/S8F4S0 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/508771:TGME49_311720 ^@ http://purl.uniprot.org/uniprot/A0A125YJG5 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/508771:TGME49_291940 ^@ http://purl.uniprot.org/uniprot/S8F3P7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_301300 ^@ http://purl.uniprot.org/uniprot/A0A125YWH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PHAX family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_202190 ^@ http://purl.uniprot.org/uniprot/S8GEJ0 ^@ Similarity ^@ Belongs to the TUB family. http://togogenome.org/gene/508771:TGME49_240080 ^@ http://purl.uniprot.org/uniprot/S8FAN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_265870 ^@ http://purl.uniprot.org/uniprot/S8EZ77 ^@ Similarity ^@ Belongs to the pantothenate synthetase family. http://togogenome.org/gene/508771:TGME49_312930 ^@ http://purl.uniprot.org/uniprot/A0A125YN40 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/508771:TGME49_286210 ^@ http://purl.uniprot.org/uniprot/S8F8G0 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/508771:TGME49_292220 ^@ http://purl.uniprot.org/uniprot/S8G8Q2 ^@ Similarity ^@ Belongs to the proteasome subunit S3 family. http://togogenome.org/gene/508771:TGME49_266680 ^@ http://purl.uniprot.org/uniprot/S8G7C8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_263410 ^@ http://purl.uniprot.org/uniprot/S8GMI2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_214260 ^@ http://purl.uniprot.org/uniprot/S8G4I1 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/508771:TGME49_266120 ^@ http://purl.uniprot.org/uniprot/S8EZ63 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/508771:TGME49_268590 ^@ http://purl.uniprot.org/uniprot/S8EXP2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_254940 ^@ http://purl.uniprot.org/uniprot/S8GIF7 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4G family. http://togogenome.org/gene/508771:TGME49_246510 ^@ http://purl.uniprot.org/uniprot/A0A125YJM5 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit. http://togogenome.org/gene/508771:TGME49_247740 ^@ http://purl.uniprot.org/uniprot/S8ERV1 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_268920 ^@ http://purl.uniprot.org/uniprot/S8F0Y2 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/508771:TGME49_275810 ^@ http://purl.uniprot.org/uniprot/A0A125YIP8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS10 family. http://togogenome.org/gene/508771:TGME49_255970 ^@ http://purl.uniprot.org/uniprot/S8GKY1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_231870 ^@ http://purl.uniprot.org/uniprot/S8GAU8 ^@ Similarity ^@ Belongs to the peroxisomal targeting signal receptor family. http://togogenome.org/gene/508771:TGME49_293390 ^@ http://purl.uniprot.org/uniprot/A0A125YRJ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c-type heme lyase family.|||Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_261470 ^@ http://purl.uniprot.org/uniprot/A0A125YG31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus http://togogenome.org/gene/508771:TGME49_286430 ^@ http://purl.uniprot.org/uniprot/S8FBJ4 ^@ Similarity ^@ Belongs to the FAM221 family. http://togogenome.org/gene/508771:TGME49_249670 ^@ http://purl.uniprot.org/uniprot/A0A125YP92 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/508771:TGME49_272510 ^@ http://purl.uniprot.org/uniprot/S8F1U5 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/508771:TGME49_212950 ^@ http://purl.uniprot.org/uniprot/A0A125YQC2 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/508771:TGME49_207440 ^@ http://purl.uniprot.org/uniprot/A0A125YYJ1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS4 family. http://togogenome.org/gene/508771:TGME49_269980 ^@ http://purl.uniprot.org/uniprot/A0A125YSW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecY/SEC61-alpha family.|||Membrane http://togogenome.org/gene/508771:TGME49_282220 ^@ http://purl.uniprot.org/uniprot/S8GEY0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_262100 ^@ http://purl.uniprot.org/uniprot/S8F1L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NASP family.|||Nucleus http://togogenome.org/gene/508771:TGME49_213072 ^@ http://purl.uniprot.org/uniprot/S8FBZ4 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/508771:TGME49_253040 ^@ http://purl.uniprot.org/uniprot/S8F7M5 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/508771:TGME49_214210 ^@ http://purl.uniprot.org/uniprot/A0A125YRK1 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruB family. http://togogenome.org/gene/508771:TGME49_207390 ^@ http://purl.uniprot.org/uniprot/A0A125YV19 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/508771:TGME49_293730 ^@ http://purl.uniprot.org/uniprot/A0A125YY95 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_294920 ^@ http://purl.uniprot.org/uniprot/S8GL40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTF2H2 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_310490 ^@ http://purl.uniprot.org/uniprot/A0A125YTM2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/508771:TGME49_237260 ^@ http://purl.uniprot.org/uniprot/S8EW57 ^@ Similarity ^@ Belongs to the CCDC124 family. http://togogenome.org/gene/508771:TGME49_234190 ^@ http://purl.uniprot.org/uniprot/S8G5B9 ^@ Function|||Similarity ^@ Belongs to the SHMT family.|||Interconversion of serine and glycine. http://togogenome.org/gene/508771:TGME49_300200 ^@ http://purl.uniprot.org/uniprot/A0A125YP81 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/508771:TGME49_311150 ^@ http://purl.uniprot.org/uniprot/A0A125YJA1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mitochondrion inner membrane|||Probably involved in the biogenesis of the COX complex. http://togogenome.org/gene/508771:TGME49_210830 ^@ http://purl.uniprot.org/uniprot/A0A125YJL9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/508771:TGME49_255220 ^@ http://purl.uniprot.org/uniprot/S8GBD9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_279450 ^@ http://purl.uniprot.org/uniprot/A0A125YFR1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Parasitic protozoa lack the de novo purine biosynthesis pathway and rely exclusively on the salvage pathway for their purine nucleotide requirements.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis.|||Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.|||Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/508771:TGME49_286720 ^@ http://purl.uniprot.org/uniprot/S8F5A4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/508771:TGME49_318730 ^@ http://purl.uniprot.org/uniprot/A0A125YMZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Membrane http://togogenome.org/gene/508771:TGME49_305940 ^@ http://purl.uniprot.org/uniprot/A0A125YUW2 ^@ Similarity ^@ Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily. http://togogenome.org/gene/508771:TGME49_217550 ^@ http://purl.uniprot.org/uniprot/S8EUU1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.|||Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_206600 ^@ http://purl.uniprot.org/uniprot/S8F2G3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. http://togogenome.org/gene/508771:TGME49_263700 ^@ http://purl.uniprot.org/uniprot/A0A125YXW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uS11 family.|||chloroplast http://togogenome.org/gene/508771:TGME49_290950 ^@ http://purl.uniprot.org/uniprot/S8G8J0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the clathrin heavy chain family.|||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.|||Cytoplasmic vesicle membrane|||coated pit http://togogenome.org/gene/508771:TGME49_202690 ^@ http://purl.uniprot.org/uniprot/A0A125YUP0 ^@ Similarity ^@ Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. http://togogenome.org/gene/508771:TGME49_305520 ^@ http://purl.uniprot.org/uniprot/A0A125YUG3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/508771:TGME49_280690 ^@ http://purl.uniprot.org/uniprot/A0A125YG40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase epsilon subunit B family.|||Nucleus http://togogenome.org/gene/508771:TGME49_266880 ^@ http://purl.uniprot.org/uniprot/S8EVZ1 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. http://togogenome.org/gene/508771:TGME49_231890 ^@ http://purl.uniprot.org/uniprot/S8F632 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. FabH family. http://togogenome.org/gene/508771:TGME49_301350 ^@ http://purl.uniprot.org/uniprot/A0A125YXW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_316190 ^@ http://purl.uniprot.org/uniprot/A0A125YVC4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Homodimer. http://togogenome.org/gene/508771:TGME49_320588 ^@ http://purl.uniprot.org/uniprot/S8F9X9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/508771:TGME49_270830 ^@ http://purl.uniprot.org/uniprot/S8F4P0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/508771:TGME49_226280 ^@ http://purl.uniprot.org/uniprot/A0A125YXA5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/508771:TGME49_252220 ^@ http://purl.uniprot.org/uniprot/S8F7Q3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_255720 ^@ http://purl.uniprot.org/uniprot/A0A125YGS4 ^@ Similarity ^@ Belongs to the tRNA-intron endonuclease family. http://togogenome.org/gene/508771:TGME49_251490 ^@ http://purl.uniprot.org/uniprot/A0A125YTL9 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/508771:TGME49_313950 ^@ http://purl.uniprot.org/uniprot/S8G2S1 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/508771:TGME49_234520 ^@ http://purl.uniprot.org/uniprot/S8ETM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the splicing factor SR family.|||Necessary for the splicing of pre-mRNA.|||Nucleus http://togogenome.org/gene/508771:TGME49_240630 ^@ http://purl.uniprot.org/uniprot/A0A125YXJ5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_299050 ^@ http://purl.uniprot.org/uniprot/A0A125YQZ8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/508771:TGME49_210380 ^@ http://purl.uniprot.org/uniprot/A0A125YQI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_236040 ^@ http://purl.uniprot.org/uniprot/A0A125YGE6 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/508771:TGME49_267460 ^@ http://purl.uniprot.org/uniprot/S8EYX0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_250750 ^@ http://purl.uniprot.org/uniprot/A0A125YR98 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_231080 ^@ http://purl.uniprot.org/uniprot/A0A125YR21 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL38 family. http://togogenome.org/gene/508771:TGME49_217870 ^@ http://purl.uniprot.org/uniprot/A0A125YSQ2 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/508771:TGME49_247690 ^@ http://purl.uniprot.org/uniprot/A0A125YTQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/508771:TGME49_205740 ^@ http://purl.uniprot.org/uniprot/S8F8Q7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC1 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_205010 ^@ http://purl.uniprot.org/uniprot/S8F8W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF3B1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_300250 ^@ http://purl.uniprot.org/uniprot/S8GAV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SWEET sugar transporter family.|||Membrane http://togogenome.org/gene/508771:TGME49_305980 ^@ http://purl.uniprot.org/uniprot/S8GG49 ^@ Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/508771:TGME49_243570 ^@ http://purl.uniprot.org/uniprot/A0A125YVY9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS26 family. http://togogenome.org/gene/508771:TGME49_237860 ^@ http://purl.uniprot.org/uniprot/A0A125YIM3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_216710 ^@ http://purl.uniprot.org/uniprot/S8EWX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_202380 ^@ http://purl.uniprot.org/uniprot/A0A125YTR8 ^@ Similarity ^@ Belongs to the Rab GDI family. http://togogenome.org/gene/508771:TGME49_213680 ^@ http://purl.uniprot.org/uniprot/A0A125YIL6 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/508771:TGME49_257710 ^@ http://purl.uniprot.org/uniprot/S8F0T1 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/508771:TGME49_231400 ^@ http://purl.uniprot.org/uniprot/A0A125YQ52 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/508771:TGME49_224160 ^@ http://purl.uniprot.org/uniprot/S8GER6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_210260 ^@ http://purl.uniprot.org/uniprot/A0A125YII4 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/508771:TGME49_202920 ^@ http://purl.uniprot.org/uniprot/S8F631 ^@ Similarity ^@ In the C-terminal section; belongs to the anthranilate synthase component I family. http://togogenome.org/gene/508771:TGME49_313790 ^@ http://purl.uniprot.org/uniprot/S8G2T0 ^@ Subcellular Location Annotation ^@ centrosome http://togogenome.org/gene/508771:TGME49_311360 ^@ http://purl.uniprot.org/uniprot/A0A125YJK5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. http://togogenome.org/gene/508771:TGME49_263800 ^@ http://purl.uniprot.org/uniprot/S8GMM7 ^@ Similarity ^@ Belongs to the eukaryotic/archaeal RNase P protein component 3 family. http://togogenome.org/gene/508771:TGME49_306620 ^@ http://purl.uniprot.org/uniprot/S8EYQ9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_259130 ^@ http://purl.uniprot.org/uniprot/S8F431 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_229170 ^@ http://purl.uniprot.org/uniprot/S8GBB9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_242730 ^@ http://purl.uniprot.org/uniprot/S8F9Y3 ^@ Similarity ^@ Belongs to the guanylate kinase family. http://togogenome.org/gene/508771:TGME49_212250 ^@ http://purl.uniprot.org/uniprot/S8G5D9 ^@ Similarity ^@ Belongs to the XPG/RAD2 endonuclease family. http://togogenome.org/gene/508771:TGME49_218810 ^@ http://purl.uniprot.org/uniprot/S8EUL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DTD family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_257490 ^@ http://purl.uniprot.org/uniprot/S8GBR5 ^@ Similarity ^@ Belongs to the prefoldin subunit alpha family. http://togogenome.org/gene/508771:TGME49_280460 ^@ http://purl.uniprot.org/uniprot/A0A125YS32 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_220440 ^@ http://purl.uniprot.org/uniprot/S8FBU5 ^@ Function|||Similarity ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. http://togogenome.org/gene/508771:TGME49_311090 ^@ http://purl.uniprot.org/uniprot/A0A125YG10 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/508771:TGME49_206610 ^@ http://purl.uniprot.org/uniprot/S8GMY7 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/508771:TGME49_304480 ^@ http://purl.uniprot.org/uniprot/A0A125YRT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family.|||Membrane http://togogenome.org/gene/508771:TGME49_298970 ^@ http://purl.uniprot.org/uniprot/A0A125YZE8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/508771:TGME49_305040 ^@ http://purl.uniprot.org/uniprot/A0A125YZ95 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_200470 ^@ http://purl.uniprot.org/uniprot/S8F0P6 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/508771:TGME49_271888 ^@ http://purl.uniprot.org/uniprot/S8F1P4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/508771:TGME49_215470 ^@ http://purl.uniprot.org/uniprot/A0A125YJN7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL1 family. http://togogenome.org/gene/508771:TGME49_272740 ^@ http://purl.uniprot.org/uniprot/S8GA09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||apicoplast http://togogenome.org/gene/508771:TGME49_211090 ^@ http://purl.uniprot.org/uniprot/A0A125YX27 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/508771:TGME49_270273 ^@ http://purl.uniprot.org/uniprot/S8F1E2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DRC10 family.|||Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.|||flagellum axoneme http://togogenome.org/gene/508771:TGME49_248330 ^@ http://purl.uniprot.org/uniprot/S8EVE5 ^@ Subcellular Location Annotation ^@ Membrane|||Peroxisome membrane http://togogenome.org/gene/508771:TGME49_248870 ^@ http://purl.uniprot.org/uniprot/S8EVJ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_280730 ^@ http://purl.uniprot.org/uniprot/A0A125YQ56 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.|||Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.|||Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.|||Cytoplasm|||Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_293600 ^@ http://purl.uniprot.org/uniprot/A0A125YP57 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/508771:TGME49_305760 ^@ http://purl.uniprot.org/uniprot/S8G6T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NSE2 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_230380 ^@ http://purl.uniprot.org/uniprot/A0A125YZ70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecE/SEC61-gamma family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_249160 ^@ http://purl.uniprot.org/uniprot/S8G9T9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_312520 ^@ http://purl.uniprot.org/uniprot/S8ERJ8 ^@ Similarity ^@ Belongs to the IPP transferase family. http://togogenome.org/gene/508771:TGME49_314820 ^@ http://purl.uniprot.org/uniprot/A0A125YU38 ^@ Similarity ^@ Belongs to the eukaryotic ATPase epsilon family. http://togogenome.org/gene/508771:TGME49_218920 ^@ http://purl.uniprot.org/uniprot/A0A125YL46 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/508771:TGME49_261720 ^@ http://purl.uniprot.org/uniprot/A0A125YGA5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_222340 ^@ http://purl.uniprot.org/uniprot/S8FE72 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_309570 ^@ http://purl.uniprot.org/uniprot/A0A125YHN4 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily. http://togogenome.org/gene/508771:TGME49_251880 ^@ http://purl.uniprot.org/uniprot/S8GAB5 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_247730 ^@ http://purl.uniprot.org/uniprot/A0A125YTS8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_315540 ^@ http://purl.uniprot.org/uniprot/S8G2C3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_307780 ^@ http://purl.uniprot.org/uniprot/S8G8F8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_204020 ^@ http://purl.uniprot.org/uniprot/A0A125YV57 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/508771:TGME49_258640 ^@ http://purl.uniprot.org/uniprot/S8F768 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/508771:TGME49_207680 ^@ http://purl.uniprot.org/uniprot/A0A125YIV5 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/508771:TGME49_244630 ^@ http://purl.uniprot.org/uniprot/S8F769 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruD family. http://togogenome.org/gene/508771:TGME49_250880 ^@ http://purl.uniprot.org/uniprot/A0A125YIJ2 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/508771:TGME49_228470 ^@ http://purl.uniprot.org/uniprot/A0A125YX57 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL15 family. http://togogenome.org/gene/508771:TGME49_248850 ^@ http://purl.uniprot.org/uniprot/A0A125YXK8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/508771:TGME49_215040 ^@ http://purl.uniprot.org/uniprot/S8G4C3 ^@ Similarity ^@ Belongs to the CAND family. http://togogenome.org/gene/508771:TGME49_281430 ^@ http://purl.uniprot.org/uniprot/S8F9R4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_260640 ^@ http://purl.uniprot.org/uniprot/S8F4C4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG9 family.|||Membrane|||Preautophagosomal structure membrane http://togogenome.org/gene/508771:TGME49_247600 ^@ http://purl.uniprot.org/uniprot/S8ERU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.|||Belongs to the dynein light intermediate chain family.|||Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).|||cytoskeleton http://togogenome.org/gene/508771:TGME49_271280 ^@ http://purl.uniprot.org/uniprot/A0A125YWY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NIP7 family.|||Interacts with pre-ribosome complex.|||Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.|||nucleolus http://togogenome.org/gene/508771:TGME49_263260 ^@ http://purl.uniprot.org/uniprot/S8F4V8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_216435 ^@ http://purl.uniprot.org/uniprot/A0A125YYC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRP17 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_285410 ^@ http://purl.uniprot.org/uniprot/A0A125YND8 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_215450 ^@ http://purl.uniprot.org/uniprot/A0A125YZH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/508771:TGME49_252465 ^@ http://purl.uniprot.org/uniprot/S8GTH0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_306260 ^@ http://purl.uniprot.org/uniprot/S8G6W2 ^@ Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. http://togogenome.org/gene/508771:TGME49_207960 ^@ http://purl.uniprot.org/uniprot/S8FF43 ^@ Similarity ^@ Belongs to the CCZ1 family. http://togogenome.org/gene/508771:TGME49_205710 ^@ http://purl.uniprot.org/uniprot/S8F2I2 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_256050 ^@ http://purl.uniprot.org/uniprot/A0A125YZB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SRP14 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.|||Cytoplasm|||Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. http://togogenome.org/gene/508771:TGME49_293372 ^@ http://purl.uniprot.org/uniprot/S8GJW4 ^@ Similarity ^@ Belongs to the RuvB family. http://togogenome.org/gene/508771:TGME49_310250 ^@ http://purl.uniprot.org/uniprot/S8ES23 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_211400 ^@ http://purl.uniprot.org/uniprot/A0A125YUM7 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/508771:TGME49_267100 ^@ http://purl.uniprot.org/uniprot/S8F273 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Enzyme with a broad specificity.|||Membrane http://togogenome.org/gene/508771:TGME49_309110 ^@ http://purl.uniprot.org/uniprot/S8EVF1 ^@ Function|||Similarity ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. http://togogenome.org/gene/508771:TGME49_270140 ^@ http://purl.uniprot.org/uniprot/A0A125YPH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DIM1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_283590 ^@ http://purl.uniprot.org/uniprot/S8FBC6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TIM50 family.|||Component of the TIM23 complex.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_248100 ^@ http://purl.uniprot.org/uniprot/S8G0D6 ^@ Similarity ^@ Belongs to the synaptobrevin family. http://togogenome.org/gene/508771:TGME49_203520 ^@ http://purl.uniprot.org/uniprot/S8GE47 ^@ Similarity ^@ Belongs to the popeye family. http://togogenome.org/gene/508771:TGME49_211230 ^@ http://purl.uniprot.org/uniprot/A0A125YGI6 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/508771:TGME49_216810 ^@ http://purl.uniprot.org/uniprot/A0A125YHM3 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/508771:TGME49_221620 ^@ http://purl.uniprot.org/uniprot/A0A125YYZ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/508771:TGME49_249010 ^@ http://purl.uniprot.org/uniprot/A0A125YH60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.|||Cytoplasm|||S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha. http://togogenome.org/gene/508771:TGME49_232040 ^@ http://purl.uniprot.org/uniprot/A0A125YN56 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/508771:TGME49_312650 ^@ http://purl.uniprot.org/uniprot/S8EY07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NELF-D family.|||Nucleus http://togogenome.org/gene/508771:TGME49_276940 ^@ http://purl.uniprot.org/uniprot/A0A125YJA3 ^@ Similarity ^@ Belongs to the RAMP4 family. http://togogenome.org/gene/508771:TGME49_225110 ^@ http://purl.uniprot.org/uniprot/S8EXB1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_217350 ^@ http://purl.uniprot.org/uniprot/A0A125YLJ5 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/508771:TGME49_225930 ^@ http://purl.uniprot.org/uniprot/A0A125YV68 ^@ Similarity|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Homodimer. http://togogenome.org/gene/508771:TGME49_276130 ^@ http://purl.uniprot.org/uniprot/A0A125YLA1 ^@ Similarity|||Subunit ^@ Belongs to the peptidase C1 family.|||Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains. http://togogenome.org/gene/508771:TGME49_298990 ^@ http://purl.uniprot.org/uniprot/A0A125YWS6 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/508771:TGME49_271120 ^@ http://purl.uniprot.org/uniprot/S8EYH8 ^@ Similarity ^@ Belongs to the neutral sphingomyelinase family. http://togogenome.org/gene/508771:TGME49_315920 ^@ http://purl.uniprot.org/uniprot/A0A125YW99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/508771:TGME49_265450 ^@ http://purl.uniprot.org/uniprot/S8F2H3 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/508771:TGME49_300130 ^@ http://purl.uniprot.org/uniprot/S8GAW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the apicomplexan parasites AMA1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_227870 ^@ http://purl.uniprot.org/uniprot/A0A125YRF3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/508771:TGME49_255900 ^@ http://purl.uniprot.org/uniprot/A0A125YLC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_216150 ^@ http://purl.uniprot.org/uniprot/A0A125YY31 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/508771:TGME49_218260 ^@ http://purl.uniprot.org/uniprot/A0A125YLK8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H3 family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/508771:TGME49_318320 ^@ http://purl.uniprot.org/uniprot/A0A125YS39 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/508771:TGME49_207665 ^@ http://purl.uniprot.org/uniprot/S8GKU0 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_228720 ^@ http://purl.uniprot.org/uniprot/S8EYC1 ^@ Similarity ^@ Belongs to the eukaryotic/archaeal RNase P protein component 1 family. http://togogenome.org/gene/508771:TGME49_225970 ^@ http://purl.uniprot.org/uniprot/S8GF82 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 31 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/508771:TGME49_320210 ^@ http://purl.uniprot.org/uniprot/A0A125YIX7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat PRP19 family.|||Homotetramer.|||Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.|||nucleoplasm http://togogenome.org/gene/508771:TGME49_205240 ^@ http://purl.uniprot.org/uniprot/S8GDU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CLPTM1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_297500 ^@ http://purl.uniprot.org/uniprot/S8FBF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. http://togogenome.org/gene/508771:TGME49_293368 ^@ http://purl.uniprot.org/uniprot/A0A125YKH3 ^@ Similarity ^@ Belongs to the RuvB family. http://togogenome.org/gene/508771:TGME49_316300 ^@ http://purl.uniprot.org/uniprot/A0A125YWZ6 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/508771:TGME49_243250 ^@ http://purl.uniprot.org/uniprot/A0A125YQD4 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/508771:TGME49_224970 ^@ http://purl.uniprot.org/uniprot/S8GEY4 ^@ Similarity ^@ Belongs to the RRP1 family. http://togogenome.org/gene/508771:TGME49_262860 ^@ http://purl.uniprot.org/uniprot/S8F1Q9 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/508771:TGME49_223960 ^@ http://purl.uniprot.org/uniprot/A0A125YXU8 ^@ Similarity ^@ Belongs to the proteasome subunit S5A family. http://togogenome.org/gene/508771:TGME49_307650 ^@ http://purl.uniprot.org/uniprot/S8EYS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.|||Mitochondrion|||Nucleus http://togogenome.org/gene/508771:TGME49_215570 ^@ http://purl.uniprot.org/uniprot/S8G483 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_258832 ^@ http://purl.uniprot.org/uniprot/S8GLH0 ^@ Similarity ^@ Belongs to the VPS52 family. http://togogenome.org/gene/508771:TGME49_246500 ^@ http://purl.uniprot.org/uniprot/A0A125YJ10 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_258770 ^@ http://purl.uniprot.org/uniprot/A0A125YYQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Membrane http://togogenome.org/gene/508771:TGME49_275750 ^@ http://purl.uniprot.org/uniprot/A0A125YK48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/508771:TGME49_220300 ^@ http://purl.uniprot.org/uniprot/S8GGY6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/508771:TGME49_226755 ^@ http://purl.uniprot.org/uniprot/S8EXP7 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_240575 ^@ http://purl.uniprot.org/uniprot/S8F7G3 ^@ Similarity ^@ Belongs to the TOP6A family. http://togogenome.org/gene/508771:TGME49_205340 ^@ http://purl.uniprot.org/uniprot/A0A125YN63 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS12 family. http://togogenome.org/gene/508771:TGME49_218570 ^@ http://purl.uniprot.org/uniprot/S8EQY7 ^@ Similarity ^@ Belongs to the NOB1 family. http://togogenome.org/gene/508771:TGME49_249702 ^@ http://purl.uniprot.org/uniprot/A0A125YVW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_288350 ^@ http://purl.uniprot.org/uniprot/S8EWP5 ^@ Similarity ^@ Belongs to the NKAP family. http://togogenome.org/gene/508771:TGME49_260140 ^@ http://purl.uniprot.org/uniprot/S8F487 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family. http://togogenome.org/gene/508771:TGME49_265190 ^@ http://purl.uniprot.org/uniprot/S8EZB2 ^@ Similarity ^@ Belongs to the peptidase C48 family. http://togogenome.org/gene/508771:TGME49_238950 ^@ http://purl.uniprot.org/uniprot/S8F4W5 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/508771:TGME49_222290 ^@ http://purl.uniprot.org/uniprot/A0A125YPL3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Cytoplasm|||LSm subunits form a heteromer with a donut shape.|||P-body|||Probably involved with other LSm subunits in the general process of degradation of mRNAs. http://togogenome.org/gene/508771:TGME49_244650 ^@ http://purl.uniprot.org/uniprot/A0A125YV35 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/508771:TGME49_315130 ^@ http://purl.uniprot.org/uniprot/A0A125YJ76 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/508771:TGME49_265220 ^@ http://purl.uniprot.org/uniprot/S8G7L7 ^@ Similarity ^@ Belongs to the GrpE family. http://togogenome.org/gene/508771:TGME49_266760 ^@ http://purl.uniprot.org/uniprot/A0A125YV86 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/508771:TGME49_219832 ^@ http://purl.uniprot.org/uniprot/S8FZB9 ^@ Function|||Similarity ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. http://togogenome.org/gene/508771:TGME49_273740 ^@ http://purl.uniprot.org/uniprot/A0A125YG32 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/508771:TGME49_216450 ^@ http://purl.uniprot.org/uniprot/A0A125YSB6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/508771:TGME49_207640 ^@ http://purl.uniprot.org/uniprot/S8FC74 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_318675 ^@ http://purl.uniprot.org/uniprot/A0A125YK27 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_314790 ^@ http://purl.uniprot.org/uniprot/A0A125YU70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/508771:TGME49_213710 ^@ http://purl.uniprot.org/uniprot/S8F5Y1 ^@ Similarity ^@ Belongs to the WD repeat LST8 family. http://togogenome.org/gene/508771:TGME49_215230 ^@ http://purl.uniprot.org/uniprot/S8EST1 ^@ Similarity ^@ Belongs to the HTATSF1 family. http://togogenome.org/gene/508771:TGME49_205520 ^@ http://purl.uniprot.org/uniprot/S8F2J1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_290850 ^@ http://purl.uniprot.org/uniprot/A0A125YRT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SMU1 family.|||Nucleus speckle http://togogenome.org/gene/508771:TGME49_286660 ^@ http://purl.uniprot.org/uniprot/S8F5B0 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_277980 ^@ http://purl.uniprot.org/uniprot/S8EWE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_273370 ^@ http://purl.uniprot.org/uniprot/A0A125YNC3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COPG family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/508771:TGME49_286740 ^@ http://purl.uniprot.org/uniprot/S8FBG4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_304670 ^@ http://purl.uniprot.org/uniprot/A0A125YYU3 ^@ Similarity ^@ Belongs to the ANP32 family. http://togogenome.org/gene/508771:TGME49_293410 ^@ http://purl.uniprot.org/uniprot/A0A125YJT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PET117 family.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_230020 ^@ http://purl.uniprot.org/uniprot/A0A125YY28 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_294440 ^@ http://purl.uniprot.org/uniprot/A0A125YK25 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_219100 ^@ http://purl.uniprot.org/uniprot/S8EUJ6 ^@ Function|||Similarity ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. http://togogenome.org/gene/508771:TGME49_251780 ^@ http://purl.uniprot.org/uniprot/A0A125YYP6 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/508771:TGME49_242290 ^@ http://purl.uniprot.org/uniprot/A0A125YL91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/508771:TGME49_272230 ^@ http://purl.uniprot.org/uniprot/S8GJ86 ^@ Similarity ^@ Belongs to the peptidase T1B family. HslV subfamily. http://togogenome.org/gene/508771:TGME49_207250 ^@ http://purl.uniprot.org/uniprot/S8EVK1 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/508771:TGME49_288685 ^@ http://purl.uniprot.org/uniprot/S8EWR7 ^@ Similarity ^@ Belongs to the HscB family. http://togogenome.org/gene/508771:TGME49_268630 ^@ http://purl.uniprot.org/uniprot/A0A125YNR4 ^@ Similarity ^@ Belongs to the RMD1/sif2 family. http://togogenome.org/gene/508771:TGME49_232710 ^@ http://purl.uniprot.org/uniprot/A0A125YZM9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS1 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).|||Cytoplasm http://togogenome.org/gene/508771:TGME49_268290 ^@ http://purl.uniprot.org/uniprot/S8G8Z4 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/508771:TGME49_234505 ^@ http://purl.uniprot.org/uniprot/A0A125YPN6 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. http://togogenome.org/gene/508771:TGME49_279330 ^@ http://purl.uniprot.org/uniprot/A0A125YT38 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily. http://togogenome.org/gene/508771:TGME49_252200 ^@ http://purl.uniprot.org/uniprot/A0A125YM35 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/508771:TGME49_232610 ^@ http://purl.uniprot.org/uniprot/A0A125YNQ7 ^@ Similarity ^@ Belongs to the EAF6 family. http://togogenome.org/gene/508771:TGME49_318330 ^@ http://purl.uniprot.org/uniprot/S8GS75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MYST (SAS/MOZ) family.|||Nucleus http://togogenome.org/gene/508771:TGME49_288610 ^@ http://purl.uniprot.org/uniprot/S8G816 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL21 family. http://togogenome.org/gene/508771:TGME49_321340 ^@ http://purl.uniprot.org/uniprot/S8FBJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAPT1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_215550 ^@ http://purl.uniprot.org/uniprot/S8EVR0 ^@ Similarity ^@ Belongs to the EXO5 family. http://togogenome.org/gene/508771:TGME49_314810 ^@ http://purl.uniprot.org/uniprot/A0A125YUF7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/508771:TGME49_252440 ^@ http://purl.uniprot.org/uniprot/A0A125YT52 ^@ Similarity ^@ Belongs to the peptidase C13 family. http://togogenome.org/gene/508771:TGME49_264670 ^@ http://purl.uniprot.org/uniprot/S8EWI2 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/508771:TGME49_221600 ^@ http://purl.uniprot.org/uniprot/S8GJG7 ^@ Similarity ^@ Belongs to the Iojap/RsfS family. http://togogenome.org/gene/508771:TGME49_212075 ^@ http://purl.uniprot.org/uniprot/S8F056 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MNS1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_284660 ^@ http://purl.uniprot.org/uniprot/A0A125YRD5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family. http://togogenome.org/gene/508771:TGME49_281450 ^@ http://purl.uniprot.org/uniprot/S8GEU6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_233340 ^@ http://purl.uniprot.org/uniprot/S8GAH3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_232580 ^@ http://purl.uniprot.org/uniprot/A0A125YTI4 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/508771:TGME49_269410 ^@ http://purl.uniprot.org/uniprot/S8EY60 ^@ Similarity ^@ Belongs to the STEEP1 family. http://togogenome.org/gene/508771:TGME49_222230 ^@ http://purl.uniprot.org/uniprot/S8F843 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MET18/MMS19 family.|||Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.|||Nucleus http://togogenome.org/gene/508771:TGME49_240960 ^@ http://purl.uniprot.org/uniprot/A0A125YQV3 ^@ Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family. http://togogenome.org/gene/508771:TGME49_215150 ^@ http://purl.uniprot.org/uniprot/S8G4B4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_293850 ^@ http://purl.uniprot.org/uniprot/A0A125YIX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CLUAP1 family.|||cilium http://togogenome.org/gene/508771:TGME49_275802 ^@ http://purl.uniprot.org/uniprot/S8GJ89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP72 family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_273790 ^@ http://purl.uniprot.org/uniprot/S8EZ00 ^@ Similarity ^@ Belongs to the ATG101 family. http://togogenome.org/gene/508771:TGME49_216930 ^@ http://purl.uniprot.org/uniprot/A0A125YYB4 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/508771:TGME49_312230 ^@ http://purl.uniprot.org/uniprot/S8ERM4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase family.|||Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.|||Homodimer. http://togogenome.org/gene/508771:TGME49_244110 ^@ http://purl.uniprot.org/uniprot/A0A125YU98 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/508771:TGME49_263050 ^@ http://purl.uniprot.org/uniprot/A0A125YII1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL13 family. http://togogenome.org/gene/508771:TGME49_310030 ^@ http://purl.uniprot.org/uniprot/A0A125YN74 ^@ Similarity ^@ Belongs to the CAP family. http://togogenome.org/gene/508771:TGME49_239820 ^@ http://purl.uniprot.org/uniprot/A0A125YMY9 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/508771:TGME49_295680 ^@ http://purl.uniprot.org/uniprot/A0A125YFJ2 ^@ Similarity ^@ Belongs to the WD repeat PWP2 family. http://togogenome.org/gene/508771:TGME49_272900 ^@ http://purl.uniprot.org/uniprot/A0A125YQJ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family. RAD51 subfamily.|||Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA.|||Nucleus http://togogenome.org/gene/508771:TGME49_233100 ^@ http://purl.uniprot.org/uniprot/A0A125YWW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_249365 ^@ http://purl.uniprot.org/uniprot/S8G0M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IFT46 family.|||cilium|||cilium basal body http://togogenome.org/gene/508771:TGME49_214840 ^@ http://purl.uniprot.org/uniprot/S8GDK2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_313390 ^@ http://purl.uniprot.org/uniprot/S8EXW9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL6 family. http://togogenome.org/gene/508771:TGME49_283710 ^@ http://purl.uniprot.org/uniprot/A0A125YW34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_285700 ^@ http://purl.uniprot.org/uniprot/S8F8L1 ^@ Similarity ^@ Belongs to the UFD1 family. http://togogenome.org/gene/508771:TGME49_263530 ^@ http://purl.uniprot.org/uniprot/A0A125YNE4 ^@ Similarity ^@ Belongs to the GroES chaperonin family. http://togogenome.org/gene/508771:TGME49_249820 ^@ http://purl.uniprot.org/uniprot/S8GA02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_250340 ^@ http://purl.uniprot.org/uniprot/A0A125YZN2 ^@ Developmental Stage|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the centrin family.|||EF-hand 1 domain binds Ca(2+) with low affinity (PubMed:32759683). EF-hand 2, EF-hand 3 and EF-hand 4 domains do not bind Ca(2+) (PubMed:32759683).|||Expressed in tachyzoites.|||In tachyzoites, plays an essential role in microneme secretion that ensures parasite motility and attachment to, invasion of and egress from host cells (PubMed:31182647, PubMed:31206964). Also involved in the architecture of the peripheral annuli where it appears to regulate the localization of PAP2 (PubMed:31206964). In association with the myosin motor MyoJ, involved in the constriction of the basal complex at the end of daughter cell division in an actin-dependent manner; the basal complex is a cytoskeletal structure formed at the tachyzoite basal pole during daughter cell formation (PubMed:28593938). May be involved in parasite replication (PubMed:31182647).|||Monomer (PubMed:32759683). Does not homooligomerize (PubMed:32759683).|||centrosome http://togogenome.org/gene/508771:TGME49_248400 ^@ http://purl.uniprot.org/uniprot/A0A125YT70 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/508771:TGME49_216220 ^@ http://purl.uniprot.org/uniprot/A0A125YFX0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_305090 ^@ http://purl.uniprot.org/uniprot/A0A125YJ73 ^@ Similarity ^@ Belongs to the CGI121/TPRKB family. http://togogenome.org/gene/508771:TGME49_213730 ^@ http://purl.uniprot.org/uniprot/S8FC38 ^@ Similarity ^@ Belongs to the LanC-like protein family. http://togogenome.org/gene/508771:TGME49_209570 ^@ http://purl.uniprot.org/uniprot/A0A125YKV9 ^@ Similarity ^@ Belongs to the REXO4 family. http://togogenome.org/gene/508771:TGME49_307840 ^@ http://purl.uniprot.org/uniprot/S8EMW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF-assemblin family.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_203580 ^@ http://purl.uniprot.org/uniprot/S8F2U9 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/508771:TGME49_217580 ^@ http://purl.uniprot.org/uniprot/A0A125YNE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/508771:TGME49_216965 ^@ http://purl.uniprot.org/uniprot/S8EQD0 ^@ Similarity ^@ Belongs to the ANP32 family. http://togogenome.org/gene/508771:TGME49_202340 ^@ http://purl.uniprot.org/uniprot/S8GNU8 ^@ Function|||Similarity ^@ Belongs to the proline oxidase family.|||Converts proline to delta-1-pyrroline-5-carboxylate. http://togogenome.org/gene/508771:TGME49_273490 ^@ http://purl.uniprot.org/uniprot/A0A125YZH5 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/508771:TGME49_320450 ^@ http://purl.uniprot.org/uniprot/A0A125YFE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRS1 family.|||Involved in ribosomal large subunit assembly.|||Nucleus http://togogenome.org/gene/508771:TGME49_278950 ^@ http://purl.uniprot.org/uniprot/A0A125YMX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/508771:TGME49_268000 ^@ http://purl.uniprot.org/uniprot/S8EXL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KIF-binding protein family.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_225250 ^@ http://purl.uniprot.org/uniprot/A0A125YQP1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/508771:TGME49_254900 ^@ http://purl.uniprot.org/uniprot/A0A125YJ30 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/508771:TGME49_212310 ^@ http://purl.uniprot.org/uniprot/S8ETZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Vacuole membrane http://togogenome.org/gene/508771:TGME49_318540 ^@ http://purl.uniprot.org/uniprot/A0A125YWA8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_229030 ^@ http://purl.uniprot.org/uniprot/S8GKQ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS2 family.|||Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_316770 ^@ http://purl.uniprot.org/uniprot/S8GBC3 ^@ Similarity ^@ Belongs to the UPP synthase family. http://togogenome.org/gene/508771:TGME49_285980 ^@ http://purl.uniprot.org/uniprot/S8GGT0 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/508771:TGME49_287500 ^@ http://purl.uniprot.org/uniprot/S8F8T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_242030 ^@ http://purl.uniprot.org/uniprot/S8FAE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COG7 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/508771:TGME49_280670 ^@ http://purl.uniprot.org/uniprot/A0A125YZI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM144 family.|||Membrane http://togogenome.org/gene/508771:TGME49_257470 ^@ http://purl.uniprot.org/uniprot/A0A125YHI7 ^@ Caution|||Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_204400 ^@ http://purl.uniprot.org/uniprot/S8F8X7 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/508771:TGME49_315440 ^@ http://purl.uniprot.org/uniprot/S8ETQ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_306290 ^@ http://purl.uniprot.org/uniprot/A0A125YX49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Nucleus http://togogenome.org/gene/508771:TGME49_306020 ^@ http://purl.uniprot.org/uniprot/S8F1T0 ^@ Similarity ^@ Belongs to the VPS13 family. http://togogenome.org/gene/508771:TGME49_231190 ^@ http://purl.uniprot.org/uniprot/A0A125YT96 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.|||Belongs to the arsA ATPase family.|||Cytoplasm|||Endoplasmic reticulum|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_255920 ^@ http://purl.uniprot.org/uniprot/A0A125YTN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GINS3/PSF3 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_319710 ^@ http://purl.uniprot.org/uniprot/S8FCV8 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_260240 ^@ http://purl.uniprot.org/uniprot/S8F7H0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAF1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_224900 ^@ http://purl.uniprot.org/uniprot/A0A125YJX9 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/508771:TGME49_263740 ^@ http://purl.uniprot.org/uniprot/S8GDA4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_278750 ^@ http://purl.uniprot.org/uniprot/S8ESJ7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_272320 ^@ http://purl.uniprot.org/uniprot/S8F4Y7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_269240 ^@ http://purl.uniprot.org/uniprot/S8GIN5 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/508771:TGME49_307610 ^@ http://purl.uniprot.org/uniprot/S8F200 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_247790 ^@ http://purl.uniprot.org/uniprot/S8ERV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAN1 family.|||Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.|||Nucleus http://togogenome.org/gene/508771:TGME49_223970 ^@ http://purl.uniprot.org/uniprot/S8F0C1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_255690 ^@ http://purl.uniprot.org/uniprot/S8F0G8 ^@ Similarity|||Subunit ^@ Belongs to the IspF family.|||Homotrimer. http://togogenome.org/gene/508771:TGME49_247610 ^@ http://purl.uniprot.org/uniprot/A0A125YYF2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. http://togogenome.org/gene/508771:TGME49_251920 ^@ http://purl.uniprot.org/uniprot/S8GAC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ESS2 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_275568 ^@ http://purl.uniprot.org/uniprot/S8GAP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGU family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_313300 ^@ http://purl.uniprot.org/uniprot/A0A125YMT3 ^@ Similarity ^@ Belongs to the VPS72/YL1 family. http://togogenome.org/gene/508771:TGME49_271860 ^@ http://purl.uniprot.org/uniprot/S8GJ59 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/508771:TGME49_219150 ^@ http://purl.uniprot.org/uniprot/S8EQV9 ^@ Similarity ^@ Belongs to the KRI1 family. http://togogenome.org/gene/508771:TGME49_253480 ^@ http://purl.uniprot.org/uniprot/S8GTC7 ^@ Similarity ^@ Belongs to the TOP6A family. http://togogenome.org/gene/508771:TGME49_267730 ^@ http://purl.uniprot.org/uniprot/S8F229 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_231280 ^@ http://purl.uniprot.org/uniprot/S8F657 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_261600 ^@ http://purl.uniprot.org/uniprot/S8GLZ3 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/508771:TGME49_288720 ^@ http://purl.uniprot.org/uniprot/A0A125YSQ4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/508771:TGME49_299150 ^@ http://purl.uniprot.org/uniprot/S8GST0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_203370 ^@ http://purl.uniprot.org/uniprot/S8F2W4 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/508771:TGME49_205040 ^@ http://purl.uniprot.org/uniprot/S8GDV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI inositol-deacylase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_263180 ^@ http://purl.uniprot.org/uniprot/A0A125YIS8 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/508771:TGME49_312540 ^@ http://purl.uniprot.org/uniprot/S8GCA2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_247230 ^@ http://purl.uniprot.org/uniprot/A0A125YHX7 ^@ Domain|||Function|||Similarity|||Subunit ^@ Acts as a calcium sensor.|||Belongs to the centrin family.|||EF-hand 1 and EF-hand 2 domains bind Ca(2+); the binding induces a conformational change which facilitates the interaction with other proteins (PubMed:32759683, PubMed:34114596). EF-hand 3 and EF-hand 4 domains do not bind Ca(2+) (PubMed:32759683).|||Monomer (PubMed:32759683, PubMed:34114596). Homooligomerizes in a Ca(2+)-dependent manner (PubMed:32759683, PubMed:34114596). Interaction via the C-terminus with other proteins disrupts and/or prevents homooligomerization (PubMed:34114596).|||The C-terminus can bind to other proteins in a Ca(2+)-independent manner; the binding disrupts and/or prevents homooligomerization. http://togogenome.org/gene/508771:TGME49_214870 ^@ http://purl.uniprot.org/uniprot/S8G4D4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family. http://togogenome.org/gene/508771:TGME49_266280 ^@ http://purl.uniprot.org/uniprot/S8G7F9 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/508771:TGME49_235170 ^@ http://purl.uniprot.org/uniprot/S8GEA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the activator 1 large subunit family.|||Nucleus http://togogenome.org/gene/508771:TGME49_215730 ^@ http://purl.uniprot.org/uniprot/A0A125YVF1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_285970 ^@ http://purl.uniprot.org/uniprot/S8F5G8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/508771:TGME49_315220 ^@ http://purl.uniprot.org/uniprot/A0A125YXB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lipase maturation factor family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_295090 ^@ http://purl.uniprot.org/uniprot/A0A125YXC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_291140 ^@ http://purl.uniprot.org/uniprot/S8F3L0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_247390 ^@ http://purl.uniprot.org/uniprot/S8EV97 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/508771:TGME49_252490 ^@ http://purl.uniprot.org/uniprot/A0A125YRI3 ^@ Similarity ^@ Belongs to the VPS29 family. http://togogenome.org/gene/508771:TGME49_248160 ^@ http://purl.uniprot.org/uniprot/S8ERW2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_222970 ^@ http://purl.uniprot.org/uniprot/A0A125YMJ0 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/508771:TGME49_318230 ^@ http://purl.uniprot.org/uniprot/A0A125YVB9 ^@ Similarity|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Monomer. http://togogenome.org/gene/508771:TGME49_280440 ^@ http://purl.uniprot.org/uniprot/A0A125YRY3 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/508771:TGME49_310130 ^@ http://purl.uniprot.org/uniprot/A0A125YY96 ^@ Similarity ^@ Belongs to the TUBGCP family. http://togogenome.org/gene/508771:TGME49_247980 ^@ http://purl.uniprot.org/uniprot/A0A125YLR3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OST5 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/508771:TGME49_210840 ^@ http://purl.uniprot.org/uniprot/A0A125YIM5 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_305120 ^@ http://purl.uniprot.org/uniprot/S8EVC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/508771:TGME49_226480 ^@ http://purl.uniprot.org/uniprot/S8F0Y0 ^@ Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. http://togogenome.org/gene/508771:TGME49_232230 ^@ http://purl.uniprot.org/uniprot/A0A125YGX9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL30 family. http://togogenome.org/gene/508771:TGME49_255710 ^@ http://purl.uniprot.org/uniprot/A0A125YIT4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_225530 ^@ http://purl.uniprot.org/uniprot/S8EUF8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_264130 ^@ http://purl.uniprot.org/uniprot/S8F8H1 ^@ Similarity ^@ Belongs to the CWC26 family. http://togogenome.org/gene/508771:TGME49_293000 ^@ http://purl.uniprot.org/uniprot/A0A125YIU9 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_225430 ^@ http://purl.uniprot.org/uniprot/S8G5T3 ^@ Similarity ^@ Belongs to the GTR/RAG GTP-binding protein family. http://togogenome.org/gene/508771:TGME49_281920 ^@ http://purl.uniprot.org/uniprot/S8F3M1 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/508771:TGME49_318600 ^@ http://purl.uniprot.org/uniprot/A0A125YRS5 ^@ Similarity ^@ Belongs to the PPC synthetase family. http://togogenome.org/gene/508771:TGME49_234610 ^@ http://purl.uniprot.org/uniprot/S8EWL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat UTP18 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_222160 ^@ http://purl.uniprot.org/uniprot/S8FE58 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/508771:TGME49_314100 ^@ http://purl.uniprot.org/uniprot/A0A125YVV0 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/508771:TGME49_290630 ^@ http://purl.uniprot.org/uniprot/S8GHU6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_214150 ^@ http://purl.uniprot.org/uniprot/A0A125YMS9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_216610 ^@ http://purl.uniprot.org/uniprot/S8GB66 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1). http://togogenome.org/gene/508771:TGME49_255270 ^@ http://purl.uniprot.org/uniprot/A0A125YTH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-50 family.|||Membrane http://togogenome.org/gene/508771:TGME49_213830 ^@ http://purl.uniprot.org/uniprot/A0A125YNM2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily. http://togogenome.org/gene/508771:TGME49_285445 ^@ http://purl.uniprot.org/uniprot/S8GGD8 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/508771:TGME49_244100 ^@ http://purl.uniprot.org/uniprot/A0A125YM09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP31 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_297730 ^@ http://purl.uniprot.org/uniprot/A0A125YVV5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELOF1 family.|||Nucleus|||Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. http://togogenome.org/gene/508771:TGME49_233200 ^@ http://purl.uniprot.org/uniprot/A0A125YVW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the URM1 family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_289250 ^@ http://purl.uniprot.org/uniprot/A0A125YZ79 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/508771:TGME49_233850 ^@ http://purl.uniprot.org/uniprot/A0A125YKD7 ^@ Similarity ^@ Belongs to the CCDC43 family. http://togogenome.org/gene/508771:TGME49_205380 ^@ http://purl.uniprot.org/uniprot/A0A125YRB2 ^@ Similarity ^@ Belongs to the FBPase class 1 family. http://togogenome.org/gene/508771:TGME49_291680 ^@ http://purl.uniprot.org/uniprot/A0A125YTJ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC23 subfamily.|||COPII-coated vesicle membrane|||Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_269680 ^@ http://purl.uniprot.org/uniprot/S8F198 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/508771:TGME49_244440 ^@ http://purl.uniprot.org/uniprot/A0A125YNC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/508771:TGME49_293420 ^@ http://purl.uniprot.org/uniprot/A0A125YQB7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_277540 ^@ http://purl.uniprot.org/uniprot/S8ESZ7 ^@ Similarity ^@ Belongs to the SLX4 family. http://togogenome.org/gene/508771:TGME49_312600 ^@ http://purl.uniprot.org/uniprot/A0A125YS40 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/508771:TGME49_202530 ^@ http://purl.uniprot.org/uniprot/S8F9A0 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily. http://togogenome.org/gene/508771:TGME49_244406 ^@ http://purl.uniprot.org/uniprot/A0A125YFC8 ^@ Cofactor|||Similarity ^@ Belongs to the cysteine dioxygenase family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/508771:TGME49_261070 ^@ http://purl.uniprot.org/uniprot/S8F1G8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_231610 ^@ http://purl.uniprot.org/uniprot/A0A125YNV1 ^@ Caution|||Similarity ^@ Belongs to the ATP:guanido phosphotransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_221420 ^@ http://purl.uniprot.org/uniprot/S8GTT5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_269480 ^@ http://purl.uniprot.org/uniprot/S8F190 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/508771:TGME49_254270 ^@ http://purl.uniprot.org/uniprot/S8F7A9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_321530 ^@ http://purl.uniprot.org/uniprot/A0A125YST9 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/508771:TGME49_290980 ^@ http://purl.uniprot.org/uniprot/A0A125YFZ0 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/508771:TGME49_287160 ^@ http://purl.uniprot.org/uniprot/S8GQZ8 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_229250 ^@ http://purl.uniprot.org/uniprot/S8F371 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL28 family. http://togogenome.org/gene/508771:TGME49_314340 ^@ http://purl.uniprot.org/uniprot/S8ETZ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_202980 ^@ http://purl.uniprot.org/uniprot/S8GNM8 ^@ Similarity ^@ Belongs to the RRP12 family. http://togogenome.org/gene/508771:TGME49_266920 ^@ http://purl.uniprot.org/uniprot/S8EZ01 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_314690 ^@ http://purl.uniprot.org/uniprot/A0A125YRF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAM41 family.|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_218280 ^@ http://purl.uniprot.org/uniprot/A0A125YIH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom40 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/508771:TGME49_290580 ^@ http://purl.uniprot.org/uniprot/A0A125YIX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_312618 ^@ http://purl.uniprot.org/uniprot/S8EY10 ^@ Similarity ^@ Belongs to the AATF family. http://togogenome.org/gene/508771:TGME49_275590 ^@ http://purl.uniprot.org/uniprot/S8GTL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/508771:TGME49_243480 ^@ http://purl.uniprot.org/uniprot/S8F3V5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/508771:TGME49_285220 ^@ http://purl.uniprot.org/uniprot/S8FB68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBCE family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_209430 ^@ http://purl.uniprot.org/uniprot/A0A125YJC0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/508771:TGME49_290670 ^@ http://purl.uniprot.org/uniprot/S8GHV2 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/508771:TGME49_229160 ^@ http://purl.uniprot.org/uniprot/S8F0B0 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/508771:TGME49_273060 ^@ http://purl.uniprot.org/uniprot/A0A125YU95 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/508771:TGME49_203320 ^@ http://purl.uniprot.org/uniprot/S8F5Z3 ^@ Function|||Similarity ^@ Belongs to the UBR1 family.|||Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. http://togogenome.org/gene/508771:TGME49_230430 ^@ http://purl.uniprot.org/uniprot/A0A125YLL7 ^@ Similarity ^@ Belongs to the synaptobrevin family. http://togogenome.org/gene/508771:TGME49_228200 ^@ http://purl.uniprot.org/uniprot/A0A125YSN4 ^@ Similarity ^@ Belongs to the V-ATPase G subunit family. http://togogenome.org/gene/508771:TGME49_248530 ^@ http://purl.uniprot.org/uniprot/S8G9P5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_252290 ^@ http://purl.uniprot.org/uniprot/A0A125YID0 ^@ Similarity ^@ Belongs to the importin alpha family. http://togogenome.org/gene/508771:TGME49_243440 ^@ http://purl.uniprot.org/uniprot/S8F3V2 ^@ Similarity ^@ Belongs to the acetyltransferase family. GCN5 subfamily. http://togogenome.org/gene/508771:TGME49_271350 ^@ http://purl.uniprot.org/uniprot/S8F4S9 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/508771:TGME49_200340 ^@ http://purl.uniprot.org/uniprot/S8GIB9 ^@ Similarity ^@ Belongs to the CFAP97 family. http://togogenome.org/gene/508771:TGME49_220420 ^@ http://purl.uniprot.org/uniprot/A0A125YGB5 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_227850 ^@ http://purl.uniprot.org/uniprot/S8GFQ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.|||Nucleus|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/508771:TGME49_267420 ^@ http://purl.uniprot.org/uniprot/S8EYX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mago nashi family.|||Nucleus http://togogenome.org/gene/508771:TGME49_312350 ^@ http://purl.uniprot.org/uniprot/A0A125YM15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IMPACT family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_315150 ^@ http://purl.uniprot.org/uniprot/A0A125YXR9 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/508771:TGME49_203840 ^@ http://purl.uniprot.org/uniprot/S8F909 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/508771:TGME49_269150 ^@ http://purl.uniprot.org/uniprot/S8G9A9 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/508771:TGME49_264950 ^@ http://purl.uniprot.org/uniprot/S8F2L1 ^@ Similarity ^@ Belongs to the TBCC family. http://togogenome.org/gene/508771:TGME49_224330 ^@ http://purl.uniprot.org/uniprot/S8F0F1 ^@ Similarity ^@ Belongs to the PA28 family. http://togogenome.org/gene/508771:TGME49_259640 ^@ http://purl.uniprot.org/uniprot/A0A125YI50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleoporin GLFG family.|||nuclear pore complex http://togogenome.org/gene/508771:TGME49_227600 ^@ http://purl.uniprot.org/uniprot/A0A125YXF3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL34 family. http://togogenome.org/gene/508771:TGME49_307980 ^@ http://purl.uniprot.org/uniprot/S8G8G7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding elongation factor family. LepA subfamily.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Mitochondrion inner membrane|||Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. http://togogenome.org/gene/508771:TGME49_206590 ^@ http://purl.uniprot.org/uniprot/S8F5F3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_215510 ^@ http://purl.uniprot.org/uniprot/S8ESQ6 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. RsmH family. http://togogenome.org/gene/508771:TGME49_273380 ^@ http://purl.uniprot.org/uniprot/A0A125YHS8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/508771:TGME49_232940 ^@ http://purl.uniprot.org/uniprot/A0A125YY54 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/508771:TGME49_243920 ^@ http://purl.uniprot.org/uniprot/A0A125YSK8 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/508771:TGME49_249650 ^@ http://purl.uniprot.org/uniprot/A0A125YQX0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the NnrE/AIBP family.|||Binds 1 potassium ion per subunit.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_245590 ^@ http://purl.uniprot.org/uniprot/S8EV13 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_244560 ^@ http://purl.uniprot.org/uniprot/A0A125YHZ8 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/508771:TGME49_226080 ^@ http://purl.uniprot.org/uniprot/S8EXJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the poly(A) polymerase family.|||Nucleus http://togogenome.org/gene/508771:TGME49_225050 ^@ http://purl.uniprot.org/uniprot/S8F0L4 ^@ Cofactor|||Similarity ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/508771:TGME49_289690 ^@ http://purl.uniprot.org/uniprot/A0A125YJ40 ^@ Similarity|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/508771:TGME49_216400 ^@ http://purl.uniprot.org/uniprot/A0A125YFK2 ^@ Similarity ^@ Belongs to the RecA family. DMC1 subfamily. http://togogenome.org/gene/508771:TGME49_269750 ^@ http://purl.uniprot.org/uniprot/S8G9F3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.|||Membrane http://togogenome.org/gene/508771:TGME49_244590 ^@ http://purl.uniprot.org/uniprot/S8FAA4 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/508771:TGME49_232730 ^@ http://purl.uniprot.org/uniprot/A0A125YHI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_263290 ^@ http://purl.uniprot.org/uniprot/S8GD47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_259960 ^@ http://purl.uniprot.org/uniprot/S8F7F2 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/508771:TGME49_218760 ^@ http://purl.uniprot.org/uniprot/S8EUM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP family.|||Membrane|||Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. http://togogenome.org/gene/508771:TGME49_243680 ^@ http://purl.uniprot.org/uniprot/S8F3X5 ^@ Similarity ^@ Belongs to the DapB family. http://togogenome.org/gene/508771:TGME49_201880 ^@ http://purl.uniprot.org/uniprot/A0A125YZ21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UQCR10/QCR9 family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_297110 ^@ http://purl.uniprot.org/uniprot/S8F8A0 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_314720 ^@ http://purl.uniprot.org/uniprot/A0A125YYL8 ^@ Similarity ^@ Belongs to the TRAPP small subunits family. Sedlin subfamily. http://togogenome.org/gene/508771:TGME49_219080 ^@ http://purl.uniprot.org/uniprot/S8G8P6 ^@ Similarity ^@ Belongs to the GET4 family. http://togogenome.org/gene/508771:TGME49_242400 ^@ http://purl.uniprot.org/uniprot/A0A125YPM7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_254410 ^@ http://purl.uniprot.org/uniprot/S8GIL8 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/508771:TGME49_253730 ^@ http://purl.uniprot.org/uniprot/A0A125YVZ6 ^@ Similarity ^@ Belongs to the XPO2/CSE1 family. http://togogenome.org/gene/508771:TGME49_233520 ^@ http://purl.uniprot.org/uniprot/A0A125YS58 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily. http://togogenome.org/gene/508771:TGME49_309820 ^@ http://purl.uniprot.org/uniprot/A0A125YTH5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL5 family. http://togogenome.org/gene/508771:TGME49_229930 ^@ http://purl.uniprot.org/uniprot/A0A125YYS6 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/508771:TGME49_319700 ^@ http://purl.uniprot.org/uniprot/A0A125YKS2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_294360 ^@ http://purl.uniprot.org/uniprot/A0A125YRG5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_249360 ^@ http://purl.uniprot.org/uniprot/A0A125YLV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RED family.|||Nucleus http://togogenome.org/gene/508771:TGME49_201210 ^@ http://purl.uniprot.org/uniprot/S8F3J0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP12 family.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_271300 ^@ http://purl.uniprot.org/uniprot/S8F4S5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/508771:TGME49_254540 ^@ http://purl.uniprot.org/uniprot/S8F778 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/508771:TGME49_290640 ^@ http://purl.uniprot.org/uniprot/S8G8G9 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||Component of the post-replicative DNA mismatch repair system (MMR). http://togogenome.org/gene/508771:TGME49_244540 ^@ http://purl.uniprot.org/uniprot/S8F760 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_205510 ^@ http://purl.uniprot.org/uniprot/S8F8S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP5/NOP56 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_240690 ^@ http://purl.uniprot.org/uniprot/A0A125YNS2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.|||Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP. http://togogenome.org/gene/508771:TGME49_267390 ^@ http://purl.uniprot.org/uniprot/A0A125YSE6 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/508771:TGME49_224860 ^@ http://purl.uniprot.org/uniprot/S8G5N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRP4 family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_209150 ^@ http://purl.uniprot.org/uniprot/A0A125YSM7 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/508771:TGME49_221922 ^@ http://purl.uniprot.org/uniprot/S8FE38 ^@ Similarity ^@ Belongs to the NifU family. http://togogenome.org/gene/508771:TGME49_246620 ^@ http://purl.uniprot.org/uniprot/A0A125YTC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BUD31 (G10) family.|||Nucleus http://togogenome.org/gene/508771:TGME49_250350 ^@ http://purl.uniprot.org/uniprot/A0A125YY74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRIPT family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_295350 ^@ http://purl.uniprot.org/uniprot/A0A125YXT9 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/508771:TGME49_305160 ^@ http://purl.uniprot.org/uniprot/A0A125YHE2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/508771:TGME49_210980 ^@ http://purl.uniprot.org/uniprot/A0A125YRL4 ^@ Similarity ^@ Belongs to the Luc7 family. http://togogenome.org/gene/508771:TGME49_262720 ^@ http://purl.uniprot.org/uniprot/A0A125YPW4 ^@ Function|||Similarity ^@ Belongs to the eIF-1A family.|||Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. http://togogenome.org/gene/508771:TGME49_248550 ^@ http://purl.uniprot.org/uniprot/S8ENU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SYG1 (TC 2.A.94) family.|||Membrane http://togogenome.org/gene/508771:TGME49_280500 ^@ http://purl.uniprot.org/uniprot/A0A125YT01 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_271390 ^@ http://purl.uniprot.org/uniprot/S8F4T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP11 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_208820 ^@ http://purl.uniprot.org/uniprot/S8F8Z5 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Homodimer. http://togogenome.org/gene/508771:TGME49_207840 ^@ http://purl.uniprot.org/uniprot/A0A125YWE8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/508771:TGME49_257740 ^@ http://purl.uniprot.org/uniprot/A0A125YI06 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/508771:TGME49_236050 ^@ http://purl.uniprot.org/uniprot/S8EZM9 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/508771:TGME49_236110 ^@ http://purl.uniprot.org/uniprot/S8GE21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG3 family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_314830 ^@ http://purl.uniprot.org/uniprot/A0A125YHT5 ^@ Similarity ^@ Belongs to the SF3B5 family. http://togogenome.org/gene/508771:TGME49_270840 ^@ http://purl.uniprot.org/uniprot/S8GIX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ARTD/PARP family.|||Nucleus http://togogenome.org/gene/508771:TGME49_307570 ^@ http://purl.uniprot.org/uniprot/S8EVM9 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/508771:TGME49_313930 ^@ http://purl.uniprot.org/uniprot/S8EU26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRT-like transporter family.|||Membrane http://togogenome.org/gene/508771:TGME49_235470 ^@ http://purl.uniprot.org/uniprot/S8G527 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/508771:TGME49_209770 ^@ http://purl.uniprot.org/uniprot/S8F8P4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_216820 ^@ http://purl.uniprot.org/uniprot/A0A125YJW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/508771:TGME49_309752 ^@ http://purl.uniprot.org/uniprot/A0A125YHZ4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/508771:TGME49_289310 ^@ http://purl.uniprot.org/uniprot/S8EWW4 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/508771:TGME49_235450 ^@ http://purl.uniprot.org/uniprot/S8ETI6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/508771:TGME49_315620 ^@ http://purl.uniprot.org/uniprot/A0A125YL36 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase C subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex. http://togogenome.org/gene/508771:TGME49_315720 ^@ http://purl.uniprot.org/uniprot/S8EQM1 ^@ Similarity ^@ Belongs to the RENT3 family. http://togogenome.org/gene/508771:TGME49_313020 ^@ http://purl.uniprot.org/uniprot/S8ERH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_245460 ^@ http://purl.uniprot.org/uniprot/A0A125YN52 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS8 family. http://togogenome.org/gene/508771:TGME49_202140 ^@ http://purl.uniprot.org/uniprot/S8GNW8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/508771:TGME49_214170 ^@ http://purl.uniprot.org/uniprot/S8G4J0 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit alpha family. http://togogenome.org/gene/508771:TGME49_240740 ^@ http://purl.uniprot.org/uniprot/A0A125YFF3 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/508771:TGME49_274190 ^@ http://purl.uniprot.org/uniprot/A0A125YWB2 ^@ Similarity ^@ Belongs to the eIF-2B gamma/epsilon subunits family. http://togogenome.org/gene/508771:TGME49_255870 ^@ http://purl.uniprot.org/uniprot/A0A125YWZ7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_249680 ^@ http://purl.uniprot.org/uniprot/A0A125YK22 ^@ Similarity ^@ Belongs to the PAF1 family. http://togogenome.org/gene/508771:TGME49_214470 ^@ http://purl.uniprot.org/uniprot/S8G4G1 ^@ Similarity ^@ Belongs to the peptidase C48 family. http://togogenome.org/gene/508771:TGME49_244020 ^@ http://purl.uniprot.org/uniprot/S8F719 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/508771:TGME49_295310 ^@ http://purl.uniprot.org/uniprot/A0A125YJN0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TBCA family.|||Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_257150 ^@ http://purl.uniprot.org/uniprot/S8GBN9 ^@ Similarity ^@ Belongs to the CNOT2/3/5 family. http://togogenome.org/gene/508771:TGME49_290890 ^@ http://purl.uniprot.org/uniprot/S8F089 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/508771:TGME49_297245 ^@ http://purl.uniprot.org/uniprot/S8FEC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_313180 ^@ http://purl.uniprot.org/uniprot/S8GC60 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. http://togogenome.org/gene/508771:TGME49_312250 ^@ http://purl.uniprot.org/uniprot/A0A125YJN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||nucleolus http://togogenome.org/gene/508771:TGME49_285720 ^@ http://purl.uniprot.org/uniprot/S8GGU9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II.|||Cytoplasm|||Nucleus|||Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/508771:TGME49_212850 ^@ http://purl.uniprot.org/uniprot/S8FBX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the proteasome inhibitor PI31 family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_272180 ^@ http://purl.uniprot.org/uniprot/S8G9W2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_228490 ^@ http://purl.uniprot.org/uniprot/S8F1L1 ^@ Similarity ^@ Belongs to the BCP1 family. http://togogenome.org/gene/508771:TGME49_257290 ^@ http://purl.uniprot.org/uniprot/S8GL47 ^@ Function|||Similarity ^@ Belongs to the KptA/TPT1 family.|||Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate. http://togogenome.org/gene/508771:TGME49_207400 ^@ http://purl.uniprot.org/uniprot/S8FF78 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CWC16 family. YJU2 subfamily.|||Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.|||Nucleus|||Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. http://togogenome.org/gene/508771:TGME49_221490 ^@ http://purl.uniprot.org/uniprot/S8FB03 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_229210 ^@ http://purl.uniprot.org/uniprot/A0A125YG92 ^@ Similarity ^@ Belongs to the U2 small nuclear ribonucleoprotein A family. http://togogenome.org/gene/508771:TGME49_295690 ^@ http://purl.uniprot.org/uniprot/A0A125YN54 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Component of a multi-subunit COQ enzyme complex.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_231140 ^@ http://purl.uniprot.org/uniprot/S8GAY1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS25 family. http://togogenome.org/gene/508771:TGME49_313280 ^@ http://purl.uniprot.org/uniprot/A0A125YRQ0 ^@ Function|||Similarity ^@ Belongs to the WD repeat CIA1 family.|||Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. http://togogenome.org/gene/508771:TGME49_294180 ^@ http://purl.uniprot.org/uniprot/A0A125YUK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Nucleus http://togogenome.org/gene/508771:TGME49_311780 ^@ http://purl.uniprot.org/uniprot/A0A125YU50 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/508771:TGME49_280750 ^@ http://purl.uniprot.org/uniprot/A0A125YUB7 ^@ Function|||Similarity ^@ Belongs to the E(R) family.|||May have a role in the cell cycle. http://togogenome.org/gene/508771:TGME49_269060 ^@ http://purl.uniprot.org/uniprot/S8F100 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/508771:TGME49_240210 ^@ http://purl.uniprot.org/uniprot/A0A125YKS7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter. http://togogenome.org/gene/508771:TGME49_217600 ^@ http://purl.uniprot.org/uniprot/A0A125YFH6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_301010 ^@ http://purl.uniprot.org/uniprot/A0A125YRR5 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/508771:TGME49_280550 ^@ http://purl.uniprot.org/uniprot/A0A125YRD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes small subunit family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. http://togogenome.org/gene/508771:TGME49_225470 ^@ http://purl.uniprot.org/uniprot/A0A125YIM7 ^@ Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family. http://togogenome.org/gene/508771:TGME49_289580 ^@ http://purl.uniprot.org/uniprot/S8F003 ^@ Similarity ^@ Belongs to the strictosidine synthase family. http://togogenome.org/gene/508771:TGME49_218720 ^@ http://purl.uniprot.org/uniprot/S8EQY1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_280710 ^@ http://purl.uniprot.org/uniprot/A0A125YIB3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase T1B family.|||Cytoplasm|||Non-catalytic component of the proteasome.|||Nucleus http://togogenome.org/gene/508771:TGME49_237140 ^@ http://purl.uniprot.org/uniprot/S8G4N2 ^@ Similarity ^@ Belongs to the PdxS/SNZ family. http://togogenome.org/gene/508771:TGME49_224950 ^@ http://purl.uniprot.org/uniprot/A0A125YQH0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_292110 ^@ http://purl.uniprot.org/uniprot/S8EXD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/508771:TGME49_263730 ^@ http://purl.uniprot.org/uniprot/S8GML9 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/508771:TGME49_217590 ^@ http://purl.uniprot.org/uniprot/A0A125YV74 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/508771:TGME49_247025 ^@ http://purl.uniprot.org/uniprot/S8G081 ^@ Similarity ^@ Belongs to the PITHD1 family. http://togogenome.org/gene/508771:TGME49_300310 ^@ http://purl.uniprot.org/uniprot/A0A125YWY3 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/508771:TGME49_267070 ^@ http://purl.uniprot.org/uniprot/S8EVX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/508771:TGME49_319500 ^@ http://purl.uniprot.org/uniprot/A0A125YUS0 ^@ Similarity ^@ Belongs to the TMEM121 family. http://togogenome.org/gene/508771:TGME49_240770 ^@ http://purl.uniprot.org/uniprot/S8GQ48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sterol desaturase family. SCS7 subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_305800 ^@ http://purl.uniprot.org/uniprot/A0A125YHD9 ^@ Similarity ^@ Belongs to the PTPS family. http://togogenome.org/gene/508771:TGME49_280740 ^@ http://purl.uniprot.org/uniprot/A0A125YQA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26B family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_261480 ^@ http://purl.uniprot.org/uniprot/S8F7P5 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_265780 ^@ http://purl.uniprot.org/uniprot/S8G7I4 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/508771:TGME49_267820 ^@ http://purl.uniprot.org/uniprot/S8GGD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ETF beta-subunit/FixA family.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion matrix|||The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/508771:TGME49_252620 ^@ http://purl.uniprot.org/uniprot/S8GTG8 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/508771:TGME49_291300 ^@ http://purl.uniprot.org/uniprot/A0A125YZA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RER1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_202370 ^@ http://purl.uniprot.org/uniprot/S8F368 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_313680 ^@ http://purl.uniprot.org/uniprot/A0A125YG98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM163 family.|||Membrane|||synaptic vesicle membrane http://togogenome.org/gene/508771:TGME49_221210 ^@ http://purl.uniprot.org/uniprot/S8F7V1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/508771:TGME49_318610 ^@ http://purl.uniprot.org/uniprot/A0A125YJZ2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_206450 ^@ http://purl.uniprot.org/uniprot/S8F2H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C54 family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_203170 ^@ http://purl.uniprot.org/uniprot/S8F2Y7 ^@ Similarity ^@ Belongs to the replication factor A protein 1 family. http://togogenome.org/gene/508771:TGME49_205030 ^@ http://purl.uniprot.org/uniprot/A0A125YLH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_215490 ^@ http://purl.uniprot.org/uniprot/S8EZA7 ^@ Disruption Phenotype|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC43A transporter (TC 2.A.1.44) family.|||Cell membrane|||Impaired parasite growth under conditions of restricted arginine availability (PubMed:28205520). Does not cause toxoplasmosis in mice (PubMed:28205520).|||Selective L-arginine transporter that is essential for parasite survival and virulence (PubMed:28205520, PubMed:30742695). Does not require other inorganic ions such as sodium, chloride, potassium or calcium (PubMed:28205520). http://togogenome.org/gene/508771:TGME49_293690 ^@ http://purl.uniprot.org/uniprot/A0A125YS70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the profilin family.|||Binds actin.|||Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_226250 ^@ http://purl.uniprot.org/uniprot/A0A125YSI7 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/508771:TGME49_221350 ^@ http://purl.uniprot.org/uniprot/S8F7W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Membrane http://togogenome.org/gene/508771:TGME49_201770 ^@ http://purl.uniprot.org/uniprot/S8GEN8 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/508771:TGME49_208790 ^@ http://purl.uniprot.org/uniprot/A0A125YYK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_313960 ^@ http://purl.uniprot.org/uniprot/S8GBY9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family. http://togogenome.org/gene/508771:TGME49_269640 ^@ http://purl.uniprot.org/uniprot/S8F4H1 ^@ Similarity ^@ Belongs to the CFAP144 family. http://togogenome.org/gene/508771:TGME49_316310 ^@ http://purl.uniprot.org/uniprot/A0A125YQP0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Homodimer. http://togogenome.org/gene/508771:TGME49_286750 ^@ http://purl.uniprot.org/uniprot/A0A125YUI4 ^@ Similarity ^@ Belongs to the PDCD4 family. http://togogenome.org/gene/508771:TGME49_266030 ^@ http://purl.uniprot.org/uniprot/S8GGV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||Nucleus|||Required for pre-mRNA splicing. http://togogenome.org/gene/508771:TGME49_292920 ^@ http://purl.uniprot.org/uniprot/A0A125YFW3 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/508771:TGME49_274090 ^@ http://purl.uniprot.org/uniprot/A0A125YYX6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/508771:TGME49_239540 ^@ http://purl.uniprot.org/uniprot/A0A125YJ86 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/508771:TGME49_289510 ^@ http://purl.uniprot.org/uniprot/S8G895 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAF1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_201400 ^@ http://purl.uniprot.org/uniprot/S8F3I3 ^@ Similarity ^@ Belongs to the SAP18 family. http://togogenome.org/gene/508771:TGME49_261780 ^@ http://purl.uniprot.org/uniprot/A0A125YX17 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_224150 ^@ http://purl.uniprot.org/uniprot/S8F0D4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COG6 family.|||Component of the conserved oligomeric Golgi complex.|||Golgi apparatus membrane|||Membrane|||Required for normal Golgi function. http://togogenome.org/gene/508771:TGME49_225140 ^@ http://purl.uniprot.org/uniprot/S8EUC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/508771:TGME49_315110 ^@ http://purl.uniprot.org/uniprot/A0A125YT66 ^@ Similarity ^@ Belongs to the prefoldin subunit alpha family. http://togogenome.org/gene/508771:TGME49_315170 ^@ http://purl.uniprot.org/uniprot/S8ETS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SepSecS family.|||Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_319550 ^@ http://purl.uniprot.org/uniprot/A0A125YZ71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_240640 ^@ http://purl.uniprot.org/uniprot/A0A125YXT2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_239260 ^@ http://purl.uniprot.org/uniprot/A0A125YHU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/508771:TGME49_300360 ^@ http://purl.uniprot.org/uniprot/A0A125YFV4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/508771:TGME49_260660 ^@ http://purl.uniprot.org/uniprot/A0A125YSK9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL23 family. http://togogenome.org/gene/508771:TGME49_318700 ^@ http://purl.uniprot.org/uniprot/A0A125YK97 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-6 family.|||Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.|||Cytoplasm|||Monomer. Associates with the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/508771:TGME49_263440 ^@ http://purl.uniprot.org/uniprot/S8F4Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP53 family.|||nucleolus|||nucleoplasm http://togogenome.org/gene/508771:TGME49_272290 ^@ http://purl.uniprot.org/uniprot/S8EYR0 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/508771:TGME49_259830 ^@ http://purl.uniprot.org/uniprot/A0A125YS22 ^@ Similarity ^@ Belongs to the eukaryotic diacylglycerol kinase family. http://togogenome.org/gene/508771:TGME49_259180 ^@ http://purl.uniprot.org/uniprot/A0A125YSJ9 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/508771:TGME49_247510 ^@ http://purl.uniprot.org/uniprot/A0A125YGG4 ^@ Similarity ^@ Belongs to the FBPase class 1 family. http://togogenome.org/gene/508771:TGME49_209160 ^@ http://purl.uniprot.org/uniprot/A0A125YVL2 ^@ Function|||Similarity ^@ Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.|||Belongs to the NMT family. http://togogenome.org/gene/508771:TGME49_227360 ^@ http://purl.uniprot.org/uniprot/A0A125YQV2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/508771:TGME49_267300 ^@ http://purl.uniprot.org/uniprot/A0A125YXB7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_266366 ^@ http://purl.uniprot.org/uniprot/S8EZ49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/508771:TGME49_205500 ^@ http://purl.uniprot.org/uniprot/S8GN30 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/508771:TGME49_298630 ^@ http://purl.uniprot.org/uniprot/A0A125YS36 ^@ Disruption Phenotype|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the vacuolar transporter chaperone (VTC) complex. The VTC complex acts as vacuolar polyphosphate polymerase that catalyzes the synthesis of inorganic polyphosphate (polyP) via transfer of phosphate from ATP to a growing polyP chain, releasing ADP. VTC exposes its catalytic domain vtc4 to the cytosol, where the growing polyP chain winds through a tunnel-shaped pocket, integrating cytoplasmic polymer synthesis with polyP membrane translocation. The VTC complex carries 9 vacuolar transmembrane domains, which are likely to constitute the translocation channel into the organelle lumen. PolyP synthesis is tightly coupled to its transport into the vacuole lumen, in order to avoid otherwise toxic intermediates in the cytosol, and it depends on the proton gradient across the membrane, formed by V-ATPase. The VTC complex also plays a role in vacuolar membrane fusion.|||Belongs to the VTC2/3 family.|||The SPX domain has very high affinity for inositol polyphosphates. SPX domains may integrate inositol pyrophosphates (PP-InsP)-dependent signaling to adapt cytosolic phosphate concentrations to different metabolic situations.|||The VTC core complex is an integral membrane heterooligomer composed of at least the catalytic subunit vtc4 and the accessory subunits vtc1 and vtc2. vtc1 is a small membrane protein without hydrophilic domain. Vtc2 and vtc4 are related and have 2 hydrophilic domains that face the cytosol, an N-terminal SPX domain and the central core domain. The central core in vtc4 is the catalytic domain.|||The VTC2 locus is refractory to knockout, and may be essential. Partial disruption of the gene results in reduced polyP accumulation.|||Vacuole membrane http://togogenome.org/gene/508771:TGME49_269960 ^@ http://purl.uniprot.org/uniprot/S8F1B8 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/508771:TGME49_224350 ^@ http://purl.uniprot.org/uniprot/S8G5K8 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/508771:TGME49_236960 ^@ http://purl.uniprot.org/uniprot/A0A125YH40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/508771:TGME49_264440 ^@ http://purl.uniprot.org/uniprot/S8GH99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP receptor beta subunit family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_209530 ^@ http://purl.uniprot.org/uniprot/S8F8V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEN-2 family.|||Membrane http://togogenome.org/gene/508771:TGME49_222090 ^@ http://purl.uniprot.org/uniprot/A0A125YWQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC6 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_295920 ^@ http://purl.uniprot.org/uniprot/A0A125YTL2 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Dynein axonemal particle|||neuron projection http://togogenome.org/gene/508771:TGME49_240840 ^@ http://purl.uniprot.org/uniprot/A0A125YYD8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ROX family.|||Binds 1 Fe(2+) ion per subunit.|||Nucleus|||Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. http://togogenome.org/gene/508771:TGME49_305310 ^@ http://purl.uniprot.org/uniprot/S8EYG8 ^@ Similarity ^@ Belongs to the XPF family. http://togogenome.org/gene/508771:TGME49_295340 ^@ http://purl.uniprot.org/uniprot/A0A125YYY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RAD23 family.|||Cytoplasm|||Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.|||Nucleus http://togogenome.org/gene/508771:TGME49_253500 ^@ http://purl.uniprot.org/uniprot/S8FAN2 ^@ Similarity ^@ Belongs to the IFT57 family. http://togogenome.org/gene/508771:TGME49_203020 ^@ http://purl.uniprot.org/uniprot/S8GE99 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. http://togogenome.org/gene/508771:TGME49_263020 ^@ http://purl.uniprot.org/uniprot/A0A125YWD8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/508771:TGME49_226730 ^@ http://purl.uniprot.org/uniprot/A0A125YJV5 ^@ Similarity ^@ Belongs to the aconitase/IPM isomerase family. http://togogenome.org/gene/508771:TGME49_249910 ^@ http://purl.uniprot.org/uniprot/A0A125YFU2 ^@ Similarity ^@ Belongs to the TIM16/PAM16 family. http://togogenome.org/gene/508771:TGME49_258070 ^@ http://purl.uniprot.org/uniprot/S8F3W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP68 family.|||Cytoplasm|||nucleolus http://togogenome.org/gene/508771:TGME49_310750 ^@ http://purl.uniprot.org/uniprot/A0A125YIQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/508771:TGME49_203110 ^@ http://purl.uniprot.org/uniprot/S8F2Z2 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/508771:TGME49_235700 ^@ http://purl.uniprot.org/uniprot/A0A125YJ68 ^@ Similarity ^@ Belongs to the FBPase class 1 family. http://togogenome.org/gene/508771:TGME49_299080 ^@ http://purl.uniprot.org/uniprot/S8GSS4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_253170 ^@ http://purl.uniprot.org/uniprot/S8FDR8 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/508771:TGME49_233820 ^@ http://purl.uniprot.org/uniprot/S8EZ53 ^@ Similarity ^@ Belongs to the DNA polymerase delta/II small subunit family. http://togogenome.org/gene/508771:TGME49_200290 ^@ http://purl.uniprot.org/uniprot/S8G8W2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_225550 ^@ http://purl.uniprot.org/uniprot/S8F0R8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_255250 ^@ http://purl.uniprot.org/uniprot/S8F6J9 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_316490 ^@ http://purl.uniprot.org/uniprot/A0A125YY30 ^@ Similarity ^@ Belongs to the NSRP1 family. http://togogenome.org/gene/508771:TGME49_284560 ^@ http://purl.uniprot.org/uniprot/A0A125YRM2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL6 family. http://togogenome.org/gene/508771:TGME49_286140 ^@ http://purl.uniprot.org/uniprot/S8GR44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GINS2/PSF2 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_297060 ^@ http://purl.uniprot.org/uniprot/S8GJT7 ^@ Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. http://togogenome.org/gene/508771:TGME49_281970 ^@ http://purl.uniprot.org/uniprot/S8F3M5 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/508771:TGME49_213890 ^@ http://purl.uniprot.org/uniprot/S8F930 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_300000 ^@ http://purl.uniprot.org/uniprot/A0A125YRB1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL18 family. http://togogenome.org/gene/508771:TGME49_266870 ^@ http://purl.uniprot.org/uniprot/S8EZ11 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_294040 ^@ http://purl.uniprot.org/uniprot/A0A125YHM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_272360 ^@ http://purl.uniprot.org/uniprot/S8EYR4 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/508771:TGME49_209960 ^@ http://purl.uniprot.org/uniprot/S8FBM5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. http://togogenome.org/gene/508771:TGME49_226410 ^@ http://purl.uniprot.org/uniprot/S8EUM4 ^@ Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family. http://togogenome.org/gene/508771:TGME49_289320 ^@ http://purl.uniprot.org/uniprot/A0A125YW65 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_216270 ^@ http://purl.uniprot.org/uniprot/A0A125YYH0 ^@ Similarity ^@ Belongs to the ANT/ATPSC lysine N-methyltransferase family. http://togogenome.org/gene/508771:TGME49_224650 ^@ http://purl.uniprot.org/uniprot/S8F0G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fungal TPase family.|||Nucleus http://togogenome.org/gene/508771:TGME49_246670 ^@ http://purl.uniprot.org/uniprot/A0A125YTC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF9 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_246920 ^@ http://purl.uniprot.org/uniprot/S8ENJ8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Cytoplasm|||Maintains high levels of reduced glutathione in the cytosol. http://togogenome.org/gene/508771:TGME49_278050 ^@ http://purl.uniprot.org/uniprot/S8ESW5 ^@ Similarity ^@ Belongs to the peptidase T1A family. http://togogenome.org/gene/508771:TGME49_320020 ^@ http://purl.uniprot.org/uniprot/A0A125YJT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_316330 ^@ http://purl.uniprot.org/uniprot/A0A125YNW0 ^@ Similarity|||Subunit ^@ Belongs to the iron/manganese superoxide dismutase family.|||Homodimer. http://togogenome.org/gene/508771:TGME49_229420 ^@ http://purl.uniprot.org/uniprot/A0A125YS54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Mitochondrion intermembrane space http://togogenome.org/gene/508771:TGME49_218370 ^@ http://purl.uniprot.org/uniprot/S8EUP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM208 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_294010 ^@ http://purl.uniprot.org/uniprot/A0A125YUK2 ^@ Similarity ^@ Belongs to the SUA5 family. http://togogenome.org/gene/508771:TGME49_267840 ^@ http://purl.uniprot.org/uniprot/S8F224 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC2 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. http://togogenome.org/gene/508771:TGME49_261240 ^@ http://purl.uniprot.org/uniprot/A0A125YSM1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H3 family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/508771:TGME49_203710 ^@ http://purl.uniprot.org/uniprot/S8F917 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_238210 ^@ http://purl.uniprot.org/uniprot/A0A125YYQ5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_310470 ^@ http://purl.uniprot.org/uniprot/A0A125YMT5 ^@ Similarity ^@ Belongs to the cytochrome c oxidase subunit 2 family. http://togogenome.org/gene/508771:TGME49_233140 ^@ http://purl.uniprot.org/uniprot/A0A125YVZ0 ^@ Function|||Similarity ^@ Belongs to the dUTPase family.|||Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/508771:TGME49_224290 ^@ http://purl.uniprot.org/uniprot/A0A125YSQ1 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/508771:TGME49_262030 ^@ http://purl.uniprot.org/uniprot/S8F7T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ALG6/ALG8 glucosyltransferase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_235860 ^@ http://purl.uniprot.org/uniprot/S8EWE8 ^@ Caution|||Similarity ^@ Belongs to the peptidase S8 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_278900 ^@ http://purl.uniprot.org/uniprot/S8G171 ^@ Similarity ^@ Belongs to the protein kinase superfamily. BUD32 family. http://togogenome.org/gene/508771:TGME49_255635 ^@ http://purl.uniprot.org/uniprot/S8F0G2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_286120 ^@ http://purl.uniprot.org/uniprot/S8F5F2 ^@ Similarity ^@ Belongs to the peptidase S9A family. http://togogenome.org/gene/508771:TGME49_300020 ^@ http://purl.uniprot.org/uniprot/S8ET60 ^@ Similarity ^@ In the C-terminal section; belongs to the peptidase M41 family.|||In the N-terminal section; belongs to the AAA ATPase family. http://togogenome.org/gene/508771:TGME49_232340 ^@ http://purl.uniprot.org/uniprot/S8F5Y7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Enzyme with a broad specificity.|||Membrane http://togogenome.org/gene/508771:TGME49_263870 ^@ http://purl.uniprot.org/uniprot/S8F214 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_268840 ^@ http://purl.uniprot.org/uniprot/S8GII7 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/508771:TGME49_214110 ^@ http://purl.uniprot.org/uniprot/S8ET38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_306410 ^@ http://purl.uniprot.org/uniprot/A0A125YMH1 ^@ Similarity ^@ Belongs to the COG3 family. http://togogenome.org/gene/508771:TGME49_251620 ^@ http://purl.uniprot.org/uniprot/A0A125YP07 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Mitochondrion|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.|||nucleolus|||nucleoplasm http://togogenome.org/gene/508771:TGME49_254140 ^@ http://purl.uniprot.org/uniprot/A0A125YKK3 ^@ Similarity ^@ Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family. http://togogenome.org/gene/508771:TGME49_246910 ^@ http://purl.uniprot.org/uniprot/A0A125YG12 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_231910 ^@ http://purl.uniprot.org/uniprot/A0A125YUH1 ^@ Similarity ^@ Belongs to the ATPase gamma chain family. http://togogenome.org/gene/508771:TGME49_313560 ^@ http://purl.uniprot.org/uniprot/A0A125YHF9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family. http://togogenome.org/gene/508771:TGME49_237200 ^@ http://purl.uniprot.org/uniprot/S8EW61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.|||Membrane http://togogenome.org/gene/508771:TGME49_321440 ^@ http://purl.uniprot.org/uniprot/S8GK42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.|||Nucleus http://togogenome.org/gene/508771:TGME49_310960 ^@ http://purl.uniprot.org/uniprot/A0A125YI40 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/508771:TGME49_275790 ^@ http://purl.uniprot.org/uniprot/S8FDW6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_203630 ^@ http://purl.uniprot.org/uniprot/A0A125YNY1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL42 family. http://togogenome.org/gene/508771:TGME49_266930 ^@ http://purl.uniprot.org/uniprot/S8EVY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TFB4 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_224460 ^@ http://purl.uniprot.org/uniprot/S8EU57 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/508771:TGME49_288920 ^@ http://purl.uniprot.org/uniprot/S8EWS9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_230010 ^@ http://purl.uniprot.org/uniprot/S8GB64 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_242680 ^@ http://purl.uniprot.org/uniprot/A0A125YZ94 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/508771:TGME49_202210 ^@ http://purl.uniprot.org/uniprot/A0A125YJL6 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/508771:TGME49_259520 ^@ http://purl.uniprot.org/uniprot/A0A125YMB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SKA2 family.|||spindle http://togogenome.org/gene/508771:TGME49_251710 ^@ http://purl.uniprot.org/uniprot/A0A125YGM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOSR1 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/508771:TGME49_272010 ^@ http://purl.uniprot.org/uniprot/A0A125YY66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GAR1 family.|||Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).|||Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.|||nucleolus http://togogenome.org/gene/508771:TGME49_297140 ^@ http://purl.uniprot.org/uniprot/S8GU68 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||Nucleus http://togogenome.org/gene/508771:TGME49_255650 ^@ http://purl.uniprot.org/uniprot/A0A125YG22 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/508771:TGME49_269660 ^@ http://purl.uniprot.org/uniprot/S8G9E4 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/508771:TGME49_203570 ^@ http://purl.uniprot.org/uniprot/S8F5W8 ^@ Similarity ^@ Belongs to the GPAT/DAPAT family. http://togogenome.org/gene/508771:TGME49_264450 ^@ http://purl.uniprot.org/uniprot/A0A125YU26 ^@ Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. http://togogenome.org/gene/508771:TGME49_254350 ^@ http://purl.uniprot.org/uniprot/A0A125YP32 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 81 family. http://togogenome.org/gene/508771:TGME49_270620 ^@ http://purl.uniprot.org/uniprot/S8EYD0 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/508771:TGME49_214230 ^@ http://purl.uniprot.org/uniprot/S8EZG7 ^@ Similarity ^@ Belongs to the dopey family. http://togogenome.org/gene/508771:TGME49_239500 ^@ http://purl.uniprot.org/uniprot/A0A125YQC4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/508771:TGME49_278870 ^@ http://purl.uniprot.org/uniprot/A0A125YRU2 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/508771:TGME49_247540 ^@ http://purl.uniprot.org/uniprot/A0A125YNB0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_227910 ^@ http://purl.uniprot.org/uniprot/A0A125YW21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UQCRQ/QCR8 family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_277500 ^@ http://purl.uniprot.org/uniprot/A0A125YSK6 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/508771:TGME49_213350 ^@ http://purl.uniprot.org/uniprot/A0A125YHZ2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS19 family. http://togogenome.org/gene/508771:TGME49_220340 ^@ http://purl.uniprot.org/uniprot/S8GRC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_321520 ^@ http://purl.uniprot.org/uniprot/A0A125YQ87 ^@ Similarity ^@ Belongs to the p23/wos2 family. http://togogenome.org/gene/508771:TGME49_216335 ^@ http://purl.uniprot.org/uniprot/S8EWT7 ^@ Similarity ^@ Belongs to the VPS13 family. http://togogenome.org/gene/508771:TGME49_219682 ^@ http://purl.uniprot.org/uniprot/S8EUE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDK/BCKDK protein kinase family.|||Mitochondrion matrix http://togogenome.org/gene/508771:TGME49_273540 ^@ http://purl.uniprot.org/uniprot/S8GA55 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_229950 ^@ http://purl.uniprot.org/uniprot/A0A125YVJ7 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/508771:TGME49_233120 ^@ http://purl.uniprot.org/uniprot/S8GJZ9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_219130 ^@ http://purl.uniprot.org/uniprot/S8G8P1 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/508771:TGME49_203690 ^@ http://purl.uniprot.org/uniprot/S8F2U2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_222710 ^@ http://purl.uniprot.org/uniprot/S8FB93 ^@ Similarity|||Subunit ^@ Belongs to the ISN1 family.|||Homotetramer. http://togogenome.org/gene/508771:TGME49_293050 ^@ http://purl.uniprot.org/uniprot/A0A125YUQ7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/508771:TGME49_288360 ^@ http://purl.uniprot.org/uniprot/A0A125YPR4 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_316320 ^@ http://purl.uniprot.org/uniprot/S8ETK1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_288750 ^@ http://purl.uniprot.org/uniprot/A0A125YYJ5 ^@ Similarity ^@ Belongs to the UQCRB/QCR7 family. http://togogenome.org/gene/508771:TGME49_233080 ^@ http://purl.uniprot.org/uniprot/A0A125YSI1 ^@ Similarity ^@ Belongs to the TFP11/STIP family. http://togogenome.org/gene/508771:TGME49_269400 ^@ http://purl.uniprot.org/uniprot/S8G9C9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/508771:TGME49_258690 ^@ http://purl.uniprot.org/uniprot/S8F773 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/508771:TGME49_215410 ^@ http://purl.uniprot.org/uniprot/A0A125YRH3 ^@ Similarity ^@ Belongs to the DPCD family. http://togogenome.org/gene/508771:TGME49_288540 ^@ http://purl.uniprot.org/uniprot/S8F309 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/508771:TGME49_272770 ^@ http://purl.uniprot.org/uniprot/S8F1X4 ^@ Similarity ^@ Belongs to the LTV1 family. http://togogenome.org/gene/508771:TGME49_270740 ^@ http://purl.uniprot.org/uniprot/S8F4N4 ^@ Similarity ^@ Belongs to the CWC15 family. http://togogenome.org/gene/508771:TGME49_254450 ^@ http://purl.uniprot.org/uniprot/S8F786 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family. Pelota subfamily.|||Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_262910 ^@ http://purl.uniprot.org/uniprot/A0A125YK00 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/508771:TGME49_248890 ^@ http://purl.uniprot.org/uniprot/S8G0J3 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/508771:TGME49_271315 ^@ http://purl.uniprot.org/uniprot/S8G9R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNAAF3 family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_246730 ^@ http://purl.uniprot.org/uniprot/S8ERP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EBP2 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_239790 ^@ http://purl.uniprot.org/uniprot/A0A125YHE3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pescadillo family.|||Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.|||nucleolus|||nucleoplasm http://togogenome.org/gene/508771:TGME49_208530 ^@ http://purl.uniprot.org/uniprot/A0A125YMB6 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/508771:TGME49_273960 ^@ http://purl.uniprot.org/uniprot/S8EZ13 ^@ Similarity ^@ Belongs to the GroES chaperonin family. http://togogenome.org/gene/508771:TGME49_316220 ^@ http://purl.uniprot.org/uniprot/A0A125YUX9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 6 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/508771:TGME49_233410 ^@ http://purl.uniprot.org/uniprot/S8F2C1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat DCAF13/WDSOF1 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_270530 ^@ http://purl.uniprot.org/uniprot/A0A125YHC6 ^@ Similarity ^@ Belongs to the UFD1 family. http://togogenome.org/gene/508771:TGME49_249270 ^@ http://purl.uniprot.org/uniprot/S8G9U7 ^@ Similarity ^@ Belongs to the protein disulfide isomerase family. http://togogenome.org/gene/508771:TGME49_222380 ^@ http://purl.uniprot.org/uniprot/A0A125YMQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Nucleus http://togogenome.org/gene/508771:TGME49_208410 ^@ http://purl.uniprot.org/uniprot/S8FF24 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_206570 ^@ http://purl.uniprot.org/uniprot/S8GMZ2 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_274060 ^@ http://purl.uniprot.org/uniprot/A0A125YNC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_295460 ^@ http://purl.uniprot.org/uniprot/A0A125YHZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOT1 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/508771:TGME49_291160 ^@ http://purl.uniprot.org/uniprot/A0A125YZF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_283730 ^@ http://purl.uniprot.org/uniprot/S8FBC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.|||Membrane http://togogenome.org/gene/508771:TGME49_290330 ^@ http://purl.uniprot.org/uniprot/S8F3F6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_234550 ^@ http://purl.uniprot.org/uniprot/A0A125YQ83 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL29 family. http://togogenome.org/gene/508771:TGME49_259980 ^@ http://purl.uniprot.org/uniprot/S8F1A9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_292010 ^@ http://purl.uniprot.org/uniprot/A0A125YL74 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/508771:TGME49_254950 ^@ http://purl.uniprot.org/uniprot/S8GSU9 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family. http://togogenome.org/gene/508771:TGME49_258150 ^@ http://purl.uniprot.org/uniprot/A0A125YZI2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/508771:TGME49_291640 ^@ http://purl.uniprot.org/uniprot/A0A125YN71 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/508771:TGME49_220530 ^@ http://purl.uniprot.org/uniprot/S8FBV1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_281990 ^@ http://purl.uniprot.org/uniprot/S8F9U2 ^@ Similarity ^@ Belongs to the isochorismatase family. http://togogenome.org/gene/508771:TGME49_249920 ^@ http://purl.uniprot.org/uniprot/A0A125YLL9 ^@ Function|||Similarity ^@ Belongs to the diphthine synthase family.|||S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis. http://togogenome.org/gene/508771:TGME49_289780 ^@ http://purl.uniprot.org/uniprot/S8GHP0 ^@ Similarity ^@ Belongs to the ClpX chaperone family. HslU subfamily. http://togogenome.org/gene/508771:TGME49_226370 ^@ http://purl.uniprot.org/uniprot/A0A125YU58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/508771:TGME49_270960 ^@ http://purl.uniprot.org/uniprot/S8EYG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP25 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_254580 ^@ http://purl.uniprot.org/uniprot/A0A125YW98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_211330 ^@ http://purl.uniprot.org/uniprot/A0A125YJJ1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/508771:TGME49_267380 ^@ http://purl.uniprot.org/uniprot/S8EVV0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_269110 ^@ http://purl.uniprot.org/uniprot/S8EY38 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/508771:TGME49_228680 ^@ http://purl.uniprot.org/uniprot/S8G6L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_269850 ^@ http://purl.uniprot.org/uniprot/A0A125YND5 ^@ Similarity ^@ Belongs to the CFAP298 family. http://togogenome.org/gene/508771:TGME49_262670 ^@ http://purl.uniprot.org/uniprot/A0A125YSP5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL20 family. http://togogenome.org/gene/508771:TGME49_264650 ^@ http://purl.uniprot.org/uniprot/S8F2Q8 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/508771:TGME49_218220 ^@ http://purl.uniprot.org/uniprot/A0A125YRL7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_266960 ^@ http://purl.uniprot.org/uniprot/A0A125YWG5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/508771:TGME49_316270 ^@ http://purl.uniprot.org/uniprot/A0A125YTJ7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the protein prenyltransferase subunit beta family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX. http://togogenome.org/gene/508771:TGME49_238230 ^@ http://purl.uniprot.org/uniprot/A0A125YUC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lariat debranching enzyme family.|||Nucleus http://togogenome.org/gene/508771:TGME49_248660 ^@ http://purl.uniprot.org/uniprot/A0A125YPQ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_290600 ^@ http://purl.uniprot.org/uniprot/A0A125YS60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/508771:TGME49_263520 ^@ http://purl.uniprot.org/uniprot/S8F1Y1 ^@ Similarity ^@ Belongs to the FAM154 family. http://togogenome.org/gene/508771:TGME49_267370 ^@ http://purl.uniprot.org/uniprot/S8EYX5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_236510 ^@ http://purl.uniprot.org/uniprot/S8G4T1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_280380 ^@ http://purl.uniprot.org/uniprot/A0A125YTH0 ^@ Similarity ^@ Belongs to the poly(ADP-ribose) glycohydrolase family. http://togogenome.org/gene/508771:TGME49_271400 ^@ http://purl.uniprot.org/uniprot/S8GJ24 ^@ Similarity ^@ Belongs to the tRNA-intron endonuclease family. http://togogenome.org/gene/508771:TGME49_224200 ^@ http://purl.uniprot.org/uniprot/S8F0D8 ^@ Similarity ^@ Belongs to the tRNA pseudouridine synthase TruA family. http://togogenome.org/gene/508771:TGME49_310810 ^@ http://purl.uniprot.org/uniprot/S8EYD5 ^@ Similarity ^@ Belongs to the apyrase family. http://togogenome.org/gene/508771:TGME49_219590 ^@ http://purl.uniprot.org/uniprot/A0A125YW15 ^@ Similarity ^@ Belongs to the RuvB family. http://togogenome.org/gene/508771:TGME49_224205 ^@ http://purl.uniprot.org/uniprot/S8GES0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_223120 ^@ http://purl.uniprot.org/uniprot/S8GJT2 ^@ Function|||Similarity ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. http://togogenome.org/gene/508771:TGME49_289730 ^@ http://purl.uniprot.org/uniprot/S8F3B1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_267350 ^@ http://purl.uniprot.org/uniprot/A0A125YGA1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures.|||Nucleus http://togogenome.org/gene/508771:TGME49_233400 ^@ http://purl.uniprot.org/uniprot/A0A125YXY7 ^@ Function|||Similarity ^@ Belongs to the adenylate kinase family. AK6 subfamily.|||Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. http://togogenome.org/gene/508771:TGME49_240540 ^@ http://purl.uniprot.org/uniprot/A0A125YTG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COG8 family.|||Membrane http://togogenome.org/gene/508771:TGME49_204460 ^@ http://purl.uniprot.org/uniprot/S8GN88 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/508771:TGME49_232240 ^@ http://purl.uniprot.org/uniprot/A0A125YPW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAPC3/SRD2 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_238250 ^@ http://purl.uniprot.org/uniprot/A0A125YHS3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL36 family. http://togogenome.org/gene/508771:TGME49_209010 ^@ http://purl.uniprot.org/uniprot/S8F8Y8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_263710 ^@ http://purl.uniprot.org/uniprot/S8F524 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_225420 ^@ http://purl.uniprot.org/uniprot/A0A125YGY7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_306080 ^@ http://purl.uniprot.org/uniprot/A0A125YLT5 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/508771:TGME49_312510 ^@ http://purl.uniprot.org/uniprot/S8EUF7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_272630 ^@ http://purl.uniprot.org/uniprot/A0A125YFN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. http://togogenome.org/gene/508771:TGME49_203270 ^@ http://purl.uniprot.org/uniprot/S8F600 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/508771:TGME49_286420 ^@ http://purl.uniprot.org/uniprot/A0A125YKL3 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/508771:TGME49_217430 ^@ http://purl.uniprot.org/uniprot/A0A125YSW9 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/508771:TGME49_271100 ^@ http://purl.uniprot.org/uniprot/S8F4R1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ESF1 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_304710 ^@ http://purl.uniprot.org/uniprot/A0A125YSN1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm|||Heterodimer of two subunits, one of which binds GTP. http://togogenome.org/gene/508771:TGME49_233020 ^@ http://purl.uniprot.org/uniprot/A0A125YXV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNOT2/3/5 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/508771:TGME49_217160 ^@ http://purl.uniprot.org/uniprot/A0A125YQQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/508771:TGME49_259010 ^@ http://purl.uniprot.org/uniprot/A0A125YPI1 ^@ Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family. http://togogenome.org/gene/508771:TGME49_238000 ^@ http://purl.uniprot.org/uniprot/S8FB56 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/508771:TGME49_215390 ^@ http://purl.uniprot.org/uniprot/S8GDE0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/508771:TGME49_231030 ^@ http://purl.uniprot.org/uniprot/A0A125YZM1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARV1 family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.|||Membrane|||Regulates also the sphingolipid metabolism. http://togogenome.org/gene/508771:TGME49_228750 ^@ http://purl.uniprot.org/uniprot/S8G6L4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_315980 ^@ http://purl.uniprot.org/uniprot/S8EQK2 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/508771:TGME49_247652 ^@ http://purl.uniprot.org/uniprot/S8EVB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the pex2/pex10/pex12 family.|||Membrane|||Peroxisome membrane http://togogenome.org/gene/508771:TGME49_289140 ^@ http://purl.uniprot.org/uniprot/A0A125YVS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL43 family.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_260170 ^@ http://purl.uniprot.org/uniprot/S8GCD1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_245580 ^@ http://purl.uniprot.org/uniprot/S8ERI8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/508771:TGME49_316240 ^@ http://purl.uniprot.org/uniprot/A0A125YKJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynactin subunit 4 family.|||centrosome|||sarcomere|||stress fiber http://togogenome.org/gene/508771:TGME49_312960 ^@ http://purl.uniprot.org/uniprot/A0A125YU39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP16 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_223660 ^@ http://purl.uniprot.org/uniprot/S8EX11 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL4 family. http://togogenome.org/gene/508771:TGME49_215060 ^@ http://purl.uniprot.org/uniprot/A0A125YHR0 ^@ Similarity ^@ Belongs to the small GTPase superfamily. SAR1 family. http://togogenome.org/gene/508771:TGME49_207710 ^@ http://purl.uniprot.org/uniprot/A0A125YUF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/508771:TGME49_222210 ^@ http://purl.uniprot.org/uniprot/S8GU03 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/508771:TGME49_319730 ^@ http://purl.uniprot.org/uniprot/A0A125YRU5 ^@ Similarity ^@ Belongs to the FAM136 family. http://togogenome.org/gene/508771:TGME49_308990 ^@ http://purl.uniprot.org/uniprot/S8ESG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/508771:TGME49_233500 ^@ http://purl.uniprot.org/uniprot/A0A125YP67 ^@ Similarity|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Homodimer. http://togogenome.org/gene/508771:TGME49_268560 ^@ http://purl.uniprot.org/uniprot/S8F447 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.|||Nucleus http://togogenome.org/gene/508771:TGME49_283840 ^@ http://purl.uniprot.org/uniprot/S8F861 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the round spermatid basic protein 1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_213800 ^@ http://purl.uniprot.org/uniprot/A0A125YFW8 ^@ Similarity ^@ Belongs to the calcineurin regulatory subunit family. http://togogenome.org/gene/508771:TGME49_313010 ^@ http://purl.uniprot.org/uniprot/A0A125YUU4 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/508771:TGME49_216560 ^@ http://purl.uniprot.org/uniprot/S8GB62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RRP8 family.|||Probable methyltransferase required to silence rDNA.|||nucleolus http://togogenome.org/gene/508771:TGME49_273200 ^@ http://purl.uniprot.org/uniprot/S8F556 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_260160 ^@ http://purl.uniprot.org/uniprot/S8GLN9 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_262140 ^@ http://purl.uniprot.org/uniprot/S8F1L7 ^@ Function|||Similarity ^@ Belongs to the AB hydrolase superfamily.|||Demethylates proteins that have been reversibly carboxymethylated. http://togogenome.org/gene/508771:TGME49_294730 ^@ http://purl.uniprot.org/uniprot/A0A125YLT4 ^@ Similarity ^@ Belongs to the SEC16 family. http://togogenome.org/gene/508771:TGME49_219540 ^@ http://purl.uniprot.org/uniprot/S8EMZ1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm|||Mitochondrion|||Monomer. http://togogenome.org/gene/508771:TGME49_240890 ^@ http://purl.uniprot.org/uniprot/A0A125YZ29 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Tetramer of two alpha (regulatory) and two beta (catalytic) chains. http://togogenome.org/gene/508771:TGME49_289650 ^@ http://purl.uniprot.org/uniprot/A0A125YIU8 ^@ Similarity ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. http://togogenome.org/gene/508771:TGME49_271060 ^@ http://purl.uniprot.org/uniprot/A0A125YXG7 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/508771:TGME49_248225 ^@ http://purl.uniprot.org/uniprot/S8EVD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DRC4 family.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_306210 ^@ http://purl.uniprot.org/uniprot/A0A125YTY4 ^@ Similarity ^@ Belongs to the CDC73 family. http://togogenome.org/gene/508771:TGME49_305010 ^@ http://purl.uniprot.org/uniprot/A0A125YY00 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_232520 ^@ http://purl.uniprot.org/uniprot/A0A125YQE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RPF2 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_238880 ^@ http://purl.uniprot.org/uniprot/S8F4W9 ^@ Similarity ^@ Belongs to the RRN3 family. http://togogenome.org/gene/508771:TGME49_297170 ^@ http://purl.uniprot.org/uniprot/A0A125YFY0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/508771:TGME49_231430 ^@ http://purl.uniprot.org/uniprot/A0A125YMR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STT3 family.|||Membrane http://togogenome.org/gene/508771:TGME49_293310 ^@ http://purl.uniprot.org/uniprot/A0A125YU12 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family. http://togogenome.org/gene/508771:TGME49_269740 ^@ http://purl.uniprot.org/uniprot/S8GIR3 ^@ Similarity ^@ Belongs to the DNA2/NAM7 helicase family. http://togogenome.org/gene/508771:TGME49_261050 ^@ http://purl.uniprot.org/uniprot/S8GLW0 ^@ Similarity ^@ Belongs to the RNR ribonuclease family. http://togogenome.org/gene/508771:TGME49_289620 ^@ http://purl.uniprot.org/uniprot/A0A125YXF9 ^@ Similarity|||Subunit ^@ Belongs to the peptidase C1 family.|||Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains. http://togogenome.org/gene/508771:TGME49_262810 ^@ http://purl.uniprot.org/uniprot/S8F4Q9 ^@ Similarity ^@ Belongs to the frataxin family. http://togogenome.org/gene/508771:TGME49_286730 ^@ http://purl.uniprot.org/uniprot/A0A125YIS9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_319860 ^@ http://purl.uniprot.org/uniprot/A0A125YJT4 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/508771:TGME49_227090 ^@ http://purl.uniprot.org/uniprot/S8F134 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/508771:TGME49_242020 ^@ http://purl.uniprot.org/uniprot/S8GPY2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 63 family. http://togogenome.org/gene/508771:TGME49_291310 ^@ http://purl.uniprot.org/uniprot/A0A125YW44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane http://togogenome.org/gene/508771:TGME49_316350 ^@ http://purl.uniprot.org/uniprot/A0A125YJ32 ^@ Similarity ^@ Belongs to the SURF6 family. http://togogenome.org/gene/508771:TGME49_235540 ^@ http://purl.uniprot.org/uniprot/A0A125YH36 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/508771:TGME49_233930 ^@ http://purl.uniprot.org/uniprot/S8GAC3 ^@ Similarity ^@ Belongs to the CAF1 family. http://togogenome.org/gene/508771:TGME49_305870 ^@ http://purl.uniprot.org/uniprot/A0A125YH45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DAD/OST2 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/508771:TGME49_228730 ^@ http://purl.uniprot.org/uniprot/S8EV89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRT-like transporter family.|||Membrane http://togogenome.org/gene/508771:TGME49_235880 ^@ http://purl.uniprot.org/uniprot/A0A125YT77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_295010 ^@ http://purl.uniprot.org/uniprot/A0A125YSZ7 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/508771:TGME49_316450 ^@ http://purl.uniprot.org/uniprot/A0A125YQD1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_232970 ^@ http://purl.uniprot.org/uniprot/A0A125YWX9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_288320 ^@ http://purl.uniprot.org/uniprot/A0A125YGW1 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/508771:TGME49_314970 ^@ http://purl.uniprot.org/uniprot/S8G2I6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.|||Endoplasmic reticulum membrane|||Probable GTP-binding protein involved in generating and maintaining the structure of the tubular endoplasmic reticulum network.|||Probable GTP-binding protein that may be involved in cell development. http://togogenome.org/gene/508771:TGME49_293670 ^@ http://purl.uniprot.org/uniprot/A0A125YM38 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_268740 ^@ http://purl.uniprot.org/uniprot/A0A125YJP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CMC family.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_217650 ^@ http://purl.uniprot.org/uniprot/A0A125YK51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DRC4 family.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_318770 ^@ http://purl.uniprot.org/uniprot/A0A125YZ48 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/508771:TGME49_259070 ^@ http://purl.uniprot.org/uniprot/A0A125YPK6 ^@ Similarity ^@ Belongs to the acetyltransferase family. MAK3 subfamily. http://togogenome.org/gene/508771:TGME49_241880 ^@ http://purl.uniprot.org/uniprot/A0A125YJG3 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_249950 ^@ http://purl.uniprot.org/uniprot/A0A125YS51 ^@ Similarity ^@ Belongs to the MAK16 family. http://togogenome.org/gene/508771:TGME49_228210 ^@ http://purl.uniprot.org/uniprot/S8G6I9 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/508771:TGME49_249760 ^@ http://purl.uniprot.org/uniprot/A0A125YJX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_293180 ^@ http://purl.uniprot.org/uniprot/A0A125YZM4 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/508771:TGME49_265140 ^@ http://purl.uniprot.org/uniprot/S8F2J5 ^@ Similarity ^@ Belongs to the FAM221 family. http://togogenome.org/gene/508771:TGME49_306470 ^@ http://purl.uniprot.org/uniprot/S8EYP5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/508771:TGME49_207770 ^@ http://purl.uniprot.org/uniprot/A0A125YQR0 ^@ Similarity ^@ Belongs to the proteasome subunit S11 family. http://togogenome.org/gene/508771:TGME49_308050 ^@ http://purl.uniprot.org/uniprot/A0A125YM00 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/508771:TGME49_313990 ^@ http://purl.uniprot.org/uniprot/S8ERA3 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/508771:TGME49_206470 ^@ http://purl.uniprot.org/uniprot/S8F5G1 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/508771:TGME49_203500 ^@ http://purl.uniprot.org/uniprot/A0A125YFM6 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/508771:TGME49_311430 ^@ http://purl.uniprot.org/uniprot/A0A125YVR6 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Fibrillarin family. http://togogenome.org/gene/508771:TGME49_224840 ^@ http://purl.uniprot.org/uniprot/S8F0J0 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_299990 ^@ http://purl.uniprot.org/uniprot/S8EQ43 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/508771:TGME49_288400 ^@ http://purl.uniprot.org/uniprot/S8EWP8 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_299110 ^@ http://purl.uniprot.org/uniprot/A0A125YNT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CLPTM1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_305030 ^@ http://purl.uniprot.org/uniprot/S8EYE9 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/508771:TGME49_218780 ^@ http://purl.uniprot.org/uniprot/S8EN29 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. http://togogenome.org/gene/508771:TGME49_286690 ^@ http://purl.uniprot.org/uniprot/S8FBG8 ^@ Similarity ^@ Belongs to the KIN17 family. http://togogenome.org/gene/508771:TGME49_273660 ^@ http://purl.uniprot.org/uniprot/S8GA64 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_263670 ^@ http://purl.uniprot.org/uniprot/S8F8B6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.|||Cytoplasm|||Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. http://togogenome.org/gene/508771:TGME49_238100 ^@ http://purl.uniprot.org/uniprot/A0A125YUL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/508771:TGME49_307800 ^@ http://purl.uniprot.org/uniprot/S8EMW2 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/508771:TGME49_268685 ^@ http://purl.uniprot.org/uniprot/S8EXQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL49 family.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_300060 ^@ http://purl.uniprot.org/uniprot/A0A125YZH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS3 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_272670 ^@ http://purl.uniprot.org/uniprot/S8GJE2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/508771:TGME49_272340 ^@ http://purl.uniprot.org/uniprot/S8GJA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SDE2 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/508771:TGME49_248390 ^@ http://purl.uniprot.org/uniprot/A0A125YI80 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL24 family. http://togogenome.org/gene/508771:TGME49_246130 ^@ http://purl.uniprot.org/uniprot/A0A125YIR4 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/508771:TGME49_223410 ^@ http://purl.uniprot.org/uniprot/A0A125YS62 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/508771:TGME49_289800 ^@ http://purl.uniprot.org/uniprot/A0A125YFZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/508771:TGME49_208020 ^@ http://purl.uniprot.org/uniprot/S8FC54 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_314000 ^@ http://purl.uniprot.org/uniprot/S8G2R7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_271810 ^@ http://purl.uniprot.org/uniprot/A0A125YXQ4 ^@ Similarity ^@ Belongs to the ANP32 family. http://togogenome.org/gene/508771:TGME49_318660 ^@ http://purl.uniprot.org/uniprot/S8F9J5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Enzyme with a broad specificity.|||Membrane http://togogenome.org/gene/508771:TGME49_260460 ^@ http://purl.uniprot.org/uniprot/A0A125YR66 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/508771:TGME49_248780 ^@ http://purl.uniprot.org/uniprot/S8EVI6 ^@ Similarity ^@ Belongs to the SRR1 family. http://togogenome.org/gene/508771:TGME49_262040 ^@ http://purl.uniprot.org/uniprot/A0A125YTI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit K family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_299070 ^@ http://purl.uniprot.org/uniprot/A0A125YUJ7 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/508771:TGME49_215070 ^@ http://purl.uniprot.org/uniprot/S8ESV1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2Fe2S plant-type ferredoxin family.|||Binds 1 [2Fe-2S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/508771:TGME49_286490 ^@ http://purl.uniprot.org/uniprot/S8GGQ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_251400 ^@ http://purl.uniprot.org/uniprot/S8G0Z3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_288210 ^@ http://purl.uniprot.org/uniprot/S8G7Y3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_294620 ^@ http://purl.uniprot.org/uniprot/S8GL66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit C family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_297800 ^@ http://purl.uniprot.org/uniprot/S8GK01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC2 subfamily.|||Nucleus http://togogenome.org/gene/508771:TGME49_293380 ^@ http://purl.uniprot.org/uniprot/A0A125YLW9 ^@ Similarity ^@ Belongs to the HAT1 family. http://togogenome.org/gene/508771:TGME49_202960 ^@ http://purl.uniprot.org/uniprot/S8F968 ^@ Similarity ^@ Belongs to the GcvH family. http://togogenome.org/gene/508771:TGME49_202310 ^@ http://purl.uniprot.org/uniprot/S8F373 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleus http://togogenome.org/gene/508771:TGME49_213650 ^@ http://purl.uniprot.org/uniprot/S8GH90 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/508771:TGME49_208780 ^@ http://purl.uniprot.org/uniprot/A0A125YLA6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/508771:TGME49_219750 ^@ http://purl.uniprot.org/uniprot/A0A125YIF5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/508771:TGME49_289070 ^@ http://purl.uniprot.org/uniprot/S8F357 ^@ Similarity ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. http://togogenome.org/gene/508771:TGME49_255400 ^@ http://purl.uniprot.org/uniprot/A0A125YQX5 ^@ Similarity ^@ Belongs to the OPA3 family. http://togogenome.org/gene/508771:TGME49_312980 ^@ http://purl.uniprot.org/uniprot/S8G2Y5 ^@ Similarity ^@ Belongs to the CFAP45 family. http://togogenome.org/gene/508771:TGME49_248600 ^@ http://purl.uniprot.org/uniprot/S8G0H2 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/508771:TGME49_290720 ^@ http://purl.uniprot.org/uniprot/S8F3H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/508771:TGME49_217220 ^@ http://purl.uniprot.org/uniprot/A0A125YVQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRE1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_308580 ^@ http://purl.uniprot.org/uniprot/A0A125YZP5 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/508771:TGME49_216010 ^@ http://purl.uniprot.org/uniprot/A0A125YTV4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/508771:TGME49_237460 ^@ http://purl.uniprot.org/uniprot/S8G4L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_203970 ^@ http://purl.uniprot.org/uniprot/S8F2R5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DDOST 48 kDa subunit family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). http://togogenome.org/gene/508771:TGME49_243655 ^@ http://purl.uniprot.org/uniprot/S8GPJ3 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/508771:TGME49_320750 ^@ http://purl.uniprot.org/uniprot/A0A125YMZ4 ^@ Similarity ^@ Belongs to the Rab GDI family. http://togogenome.org/gene/508771:TGME49_246178 ^@ http://purl.uniprot.org/uniprot/S8EV39 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_221570 ^@ http://purl.uniprot.org/uniprot/S8F7Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ESF2/ABP1 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_254440 ^@ http://purl.uniprot.org/uniprot/A0A125YT49 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/508771:TGME49_251810 ^@ http://purl.uniprot.org/uniprot/A0A125YIS4 ^@ Function|||PTM|||Similarity ^@ Belongs to the eIF-5A family.|||Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. http://togogenome.org/gene/508771:TGME49_293610 ^@ http://purl.uniprot.org/uniprot/A0A125YRM5 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily. http://togogenome.org/gene/508771:TGME49_246060 ^@ http://purl.uniprot.org/uniprot/S8ENG7 ^@ Function|||Similarity ^@ Belongs to the phage and mitochondrial RNA polymerase family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/508771:TGME49_236020 ^@ http://purl.uniprot.org/uniprot/S8EWD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_211720 ^@ http://purl.uniprot.org/uniprot/A0A125YK17 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_244200 ^@ http://purl.uniprot.org/uniprot/S8F732 ^@ Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family. http://togogenome.org/gene/508771:TGME49_246040 ^@ http://purl.uniprot.org/uniprot/S8G996 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_307603 ^@ http://purl.uniprot.org/uniprot/S8EVN3 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/508771:TGME49_203940 ^@ http://purl.uniprot.org/uniprot/S8GNC9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family. http://togogenome.org/gene/508771:TGME49_220250 ^@ http://purl.uniprot.org/uniprot/A0A125YNK6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_299210 ^@ http://purl.uniprot.org/uniprot/A0A125YT78 ^@ Function|||Similarity ^@ Belongs to the CTP synthase family.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. http://togogenome.org/gene/508771:TGME49_209080 ^@ http://purl.uniprot.org/uniprot/A0A125YV90 ^@ Similarity ^@ Belongs to the TRAPP small subunits family. BET3 subfamily. http://togogenome.org/gene/508771:TGME49_281420 ^@ http://purl.uniprot.org/uniprot/S8F6L4 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/508771:TGME49_233550 ^@ http://purl.uniprot.org/uniprot/S8GAF2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the COQ10 family.|||Interacts with coenzyme Q.|||Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes. http://togogenome.org/gene/508771:TGME49_300380 ^@ http://purl.uniprot.org/uniprot/S8G1J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EROs family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/508771:TGME49_261950 ^@ http://purl.uniprot.org/uniprot/A0A125YYY5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/508771:TGME49_245510 ^@ http://purl.uniprot.org/uniprot/S8G002 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_286610 ^@ http://purl.uniprot.org/uniprot/A0A125YHY5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS14 family. http://togogenome.org/gene/508771:TGME49_239330 ^@ http://purl.uniprot.org/uniprot/A0A125YUV2 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL37 family.|||Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. http://togogenome.org/gene/508771:TGME49_257945 ^@ http://purl.uniprot.org/uniprot/S8GBX9 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_267480 ^@ http://purl.uniprot.org/uniprot/S8EVU0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. http://togogenome.org/gene/508771:TGME49_231900 ^@ http://purl.uniprot.org/uniprot/A0A125YV71 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/508771:TGME49_215930 ^@ http://purl.uniprot.org/uniprot/A0A125YK73 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_250870 ^@ http://purl.uniprot.org/uniprot/A0A125YQ38 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/508771:TGME49_290240 ^@ http://purl.uniprot.org/uniprot/S8G8F1 ^@ Similarity ^@ Belongs to the TCF25 family. http://togogenome.org/gene/508771:TGME49_237470 ^@ http://purl.uniprot.org/uniprot/S8GDT8 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/508771:TGME49_267080 ^@ http://purl.uniprot.org/uniprot/S8G794 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/508771:TGME49_261460 ^@ http://purl.uniprot.org/uniprot/A0A125YVQ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SSRP1 family.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.|||Nucleus http://togogenome.org/gene/508771:TGME49_283830 ^@ http://purl.uniprot.org/uniprot/S8FBB0 ^@ Similarity ^@ Belongs to the PPase family. http://togogenome.org/gene/508771:TGME49_289080 ^@ http://purl.uniprot.org/uniprot/S8GHH0 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/508771:TGME49_255190 ^@ http://purl.uniprot.org/uniprot/A0A125YKI1 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/508771:TGME49_266390 ^@ http://purl.uniprot.org/uniprot/S8F2C3 ^@ Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family. http://togogenome.org/gene/508771:TGME49_313830 ^@ http://purl.uniprot.org/uniprot/A0A125YYP7 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/508771:TGME49_224235 ^@ http://purl.uniprot.org/uniprot/S8F0E3 ^@ Similarity ^@ Belongs to the IF-3 family. http://togogenome.org/gene/508771:TGME49_261210 ^@ http://purl.uniprot.org/uniprot/A0A125YZG9 ^@ Similarity ^@ Belongs to the proteasome subunit p55 family. http://togogenome.org/gene/508771:TGME49_266850 ^@ http://purl.uniprot.org/uniprot/S8GGN6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.|||Component of a multi-subunit COQ enzyme complex.|||Mitochondrion inner membrane|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/508771:TGME49_249380 ^@ http://purl.uniprot.org/uniprot/S8ES43 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/508771:TGME49_232690 ^@ http://purl.uniprot.org/uniprot/S8EZQ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_269010 ^@ http://purl.uniprot.org/uniprot/S8F0Y8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_207930 ^@ http://purl.uniprot.org/uniprot/A0A125YWH5 ^@ Similarity ^@ Belongs to the phosphatidylethanolamine-binding protein family. http://togogenome.org/gene/508771:TGME49_226430 ^@ http://purl.uniprot.org/uniprot/S8F0X6 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_232250 ^@ http://purl.uniprot.org/uniprot/A0A125YV29 ^@ Function|||Similarity ^@ Belongs to the catalase family.|||Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. http://togogenome.org/gene/508771:TGME49_230580 ^@ http://purl.uniprot.org/uniprot/S8F017 ^@ Similarity ^@ Belongs to the CDC123 family. http://togogenome.org/gene/508771:TGME49_224800 ^@ http://purl.uniprot.org/uniprot/A0A125YY69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_213970 ^@ http://purl.uniprot.org/uniprot/A0A125YFC7 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_221170 ^@ http://purl.uniprot.org/uniprot/A0A125YGE3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48A family.|||Binds 1 zinc ion per subunit.|||Endoplasmic reticulum membrane|||Proteolytically removes the C-terminal three residues of farnesylated proteins. http://togogenome.org/gene/508771:TGME49_232300 ^@ http://purl.uniprot.org/uniprot/S8EZS1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS3 family. http://togogenome.org/gene/508771:TGME49_301290 ^@ http://purl.uniprot.org/uniprot/A0A125YGX2 ^@ Similarity ^@ Belongs to the GTR/RAG GTP-binding protein family. http://togogenome.org/gene/508771:TGME49_211680 ^@ http://purl.uniprot.org/uniprot/A0A125YQJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein disulfide isomerase family.|||Endoplasmic reticulum lumen http://togogenome.org/gene/508771:TGME49_222850 ^@ http://purl.uniprot.org/uniprot/A0A125YS65 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/508771:TGME49_278882 ^@ http://purl.uniprot.org/uniprot/A0A125YXK3 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/508771:TGME49_266730 ^@ http://purl.uniprot.org/uniprot/S8G7C3 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_228080 ^@ http://purl.uniprot.org/uniprot/S8EUZ6 ^@ Similarity ^@ Belongs to the dus family. Dus3 subfamily. http://togogenome.org/gene/508771:TGME49_220100 ^@ http://purl.uniprot.org/uniprot/S8F5K6 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/508771:TGME49_201690 ^@ http://purl.uniprot.org/uniprot/S8F9H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/508771:TGME49_217760 ^@ http://purl.uniprot.org/uniprot/S8ENA6 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. http://togogenome.org/gene/508771:TGME49_307850 ^@ http://purl.uniprot.org/uniprot/S8EQR1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/508771:TGME49_230960 ^@ http://purl.uniprot.org/uniprot/A0A125YIG4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_214810 ^@ http://purl.uniprot.org/uniprot/A0A125YP96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_249250 ^@ http://purl.uniprot.org/uniprot/A0A125YPQ7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL33 family. http://togogenome.org/gene/508771:TGME49_264870 ^@ http://purl.uniprot.org/uniprot/S8GH43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_248370 ^@ http://purl.uniprot.org/uniprot/A0A125YIJ1 ^@ Similarity ^@ Belongs to the prefoldin subunit beta family. http://togogenome.org/gene/508771:TGME49_262480 ^@ http://purl.uniprot.org/uniprot/S8GCV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.|||Belongs to the GAMAD family.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_315770 ^@ http://purl.uniprot.org/uniprot/S8EQL7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/508771:TGME49_281545 ^@ http://purl.uniprot.org/uniprot/S8GP55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRM6/GCD10 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_238220 ^@ http://purl.uniprot.org/uniprot/A0A125YRU3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_226010 ^@ http://purl.uniprot.org/uniprot/A0A125YJC8 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/508771:TGME49_309560 ^@ http://purl.uniprot.org/uniprot/A0A125YU36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_204060 ^@ http://purl.uniprot.org/uniprot/S8GE00 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/508771:TGME49_276910 ^@ http://purl.uniprot.org/uniprot/A0A125YNE1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/508771:TGME49_237110 ^@ http://purl.uniprot.org/uniprot/A0A125YUA5 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/508771:TGME49_286090 ^@ http://purl.uniprot.org/uniprot/A0A125YYZ5 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/508771:TGME49_219600 ^@ http://purl.uniprot.org/uniprot/S8EQU4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_233090 ^@ http://purl.uniprot.org/uniprot/S8F2K0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.|||Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Nucleus http://togogenome.org/gene/508771:TGME49_320560 ^@ http://purl.uniprot.org/uniprot/A0A125YKF1 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/508771:TGME49_314042 ^@ http://purl.uniprot.org/uniprot/A0A125YX38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c-type heme lyase family.|||Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_243500 ^@ http://purl.uniprot.org/uniprot/S8FA29 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_315210 ^@ http://purl.uniprot.org/uniprot/S8G2G8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lipase maturation factor family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_245670 ^@ http://purl.uniprot.org/uniprot/S8ENF7 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/508771:TGME49_263090 ^@ http://purl.uniprot.org/uniprot/A0A125YLJ4 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/508771:TGME49_284540 ^@ http://purl.uniprot.org/uniprot/A0A125YKG0 ^@ Similarity ^@ Belongs to the ATPase delta chain family. http://togogenome.org/gene/508771:TGME49_226960 ^@ http://purl.uniprot.org/uniprot/A0A125YKV6 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric.|||Tetramer of two alpha (regulatory) and two beta (catalytic) chains. http://togogenome.org/gene/508771:TGME49_239550 ^@ http://purl.uniprot.org/uniprot/A0A125YJI3 ^@ Similarity ^@ Belongs to the GAMAD family. http://togogenome.org/gene/508771:TGME49_254750 ^@ http://purl.uniprot.org/uniprot/A0A125YL59 ^@ Similarity ^@ Belongs to the CFAP91 family. http://togogenome.org/gene/508771:TGME49_266090 ^@ http://purl.uniprot.org/uniprot/A0A125YZ44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM43 family.|||Membrane http://togogenome.org/gene/508771:TGME49_275600 ^@ http://purl.uniprot.org/uniprot/S8GJ69 ^@ Similarity ^@ Belongs to the diacylglycerol acyltransferase family. http://togogenome.org/gene/508771:TGME49_242380 ^@ http://purl.uniprot.org/uniprot/S8F9W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/508771:TGME49_258700 ^@ http://purl.uniprot.org/uniprot/A0A125YTA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/508771:TGME49_264840 ^@ http://purl.uniprot.org/uniprot/S8F2M1 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/508771:TGME49_224110 ^@ http://purl.uniprot.org/uniprot/S8G5J3 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/508771:TGME49_257480 ^@ http://purl.uniprot.org/uniprot/S8GL69 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/508771:TGME49_260250 ^@ http://purl.uniprot.org/uniprot/S8GLP8 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/508771:TGME49_285230 ^@ http://purl.uniprot.org/uniprot/A0A125YPV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_267330 ^@ http://purl.uniprot.org/uniprot/S8EVV6 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/508771:TGME49_272910 ^@ http://purl.uniprot.org/uniprot/A0A125YUI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_283765 ^@ http://purl.uniprot.org/uniprot/S8GGJ3 ^@ Subcellular Location Annotation ^@ cilium basal body http://togogenome.org/gene/508771:TGME49_254460 ^@ http://purl.uniprot.org/uniprot/A0A125YW13 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_243950 ^@ http://purl.uniprot.org/uniprot/A0A125YRG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_266640 ^@ http://purl.uniprot.org/uniprot/A0A125YT21 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/508771:TGME49_263490 ^@ http://purl.uniprot.org/uniprot/A0A125YIU2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/508771:TGME49_260220 ^@ http://purl.uniprot.org/uniprot/S8F1C1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/508771:TGME49_267590 ^@ http://purl.uniprot.org/uniprot/S8F244 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_229750 ^@ http://purl.uniprot.org/uniprot/S8GB77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the THOC5 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_319870 ^@ http://purl.uniprot.org/uniprot/A0A125YWR5 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/508771:TGME49_281490 ^@ http://purl.uniprot.org/uniprot/S8GP52 ^@ Similarity ^@ Belongs to the glutaminase PdxT/SNO family. http://togogenome.org/gene/508771:TGME49_207430 ^@ http://purl.uniprot.org/uniprot/S8FF75 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family. DDX1 subfamily.|||RNA helicase.|||The helicase domain is involved in the stimulation of RELA transcriptional activity. http://togogenome.org/gene/508771:TGME49_231210 ^@ http://purl.uniprot.org/uniprot/A0A125YPI0 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/508771:TGME49_286782 ^@ http://purl.uniprot.org/uniprot/S8FBG0 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the copper/topaquinone oxidase family.|||Contains 1 topaquinone per subunit.|||Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. http://togogenome.org/gene/508771:TGME49_309370 ^@ http://purl.uniprot.org/uniprot/A0A125YWW7 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/508771:TGME49_264860 ^@ http://purl.uniprot.org/uniprot/S8EWF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LTN1 family.|||cytosol http://togogenome.org/gene/508771:TGME49_305860 ^@ http://purl.uniprot.org/uniprot/A0A125YQG4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_241160 ^@ http://purl.uniprot.org/uniprot/A0A125YHN5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_229180 ^@ http://purl.uniprot.org/uniprot/A0A125YUH4 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/508771:TGME49_254520 ^@ http://purl.uniprot.org/uniprot/A0A125YY52 ^@ Similarity ^@ Belongs to the prefoldin subunit beta family. http://togogenome.org/gene/508771:TGME49_245490 ^@ http://purl.uniprot.org/uniprot/A0A125YRT0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_253030 ^@ http://purl.uniprot.org/uniprot/S8GTF8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/508771:TGME49_207070 ^@ http://purl.uniprot.org/uniprot/S8EVL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ALG14 family.|||Endoplasmic reticulum membrane|||Membrane|||Nucleus membrane http://togogenome.org/gene/508771:TGME49_261610 ^@ http://purl.uniprot.org/uniprot/S8GCP6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XPF family.|||Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).|||Interacts with EME1.|||Nucleus http://togogenome.org/gene/508771:TGME49_209240 ^@ http://purl.uniprot.org/uniprot/S8FC00 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/508771:TGME49_253900 ^@ http://purl.uniprot.org/uniprot/S8F7E9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ALAD family.|||Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.|||Homooctamer. http://togogenome.org/gene/508771:TGME49_262380 ^@ http://purl.uniprot.org/uniprot/A0A125YJ84 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/508771:TGME49_250740 ^@ http://purl.uniprot.org/uniprot/A0A125YYP5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/508771:TGME49_246650 ^@ http://purl.uniprot.org/uniprot/S8G054 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/508771:TGME49_290960 ^@ http://purl.uniprot.org/uniprot/S8EX81 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/508771:TGME49_290970 ^@ http://purl.uniprot.org/uniprot/A0A125YGM8 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/508771:TGME49_242800 ^@ http://purl.uniprot.org/uniprot/A0A125YNA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.|||Component of the pre-66S ribosomal particle.|||Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.|||nucleolus http://togogenome.org/gene/508771:TGME49_312280 ^@ http://purl.uniprot.org/uniprot/A0A125YKC6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_311810 ^@ http://purl.uniprot.org/uniprot/S8G355 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit alpha family. http://togogenome.org/gene/508771:TGME49_315550 ^@ http://purl.uniprot.org/uniprot/A0A125YSW8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_311410 ^@ http://purl.uniprot.org/uniprot/A0A125YVF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MPP10 family.|||nucleolus http://togogenome.org/gene/508771:TGME49_270380 ^@ http://purl.uniprot.org/uniprot/A0A125YSG4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/508771:TGME49_239100 ^@ http://purl.uniprot.org/uniprot/A0A125YZ19 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS7 family. http://togogenome.org/gene/508771:TGME49_240870 ^@ http://purl.uniprot.org/uniprot/S8GQ34 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/508771:TGME49_240550 ^@ http://purl.uniprot.org/uniprot/A0A125YM89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX17 family.|||Mitochondrion intermembrane space http://togogenome.org/gene/508771:TGME49_256000 ^@ http://purl.uniprot.org/uniprot/A0A125YGT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_219800 ^@ http://purl.uniprot.org/uniprot/A0A125YPJ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex. http://togogenome.org/gene/508771:TGME49_216730 ^@ http://purl.uniprot.org/uniprot/S8GB78 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/508771:TGME49_269140 ^@ http://purl.uniprot.org/uniprot/A0A125YRD0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum|||Part of the multisubunit TRAPP (transport protein particle) complex.|||cis-Golgi network http://togogenome.org/gene/508771:TGME49_209290 ^@ http://purl.uniprot.org/uniprot/A0A125YJ28 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family. http://togogenome.org/gene/508771:TGME49_268640 ^@ http://purl.uniprot.org/uniprot/A0A125YTZ0 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/508771:TGME49_241165 ^@ http://purl.uniprot.org/uniprot/A0A125YRV7 ^@ Similarity ^@ Belongs to the CFAP97 family. http://togogenome.org/gene/508771:TGME49_217780 ^@ http://purl.uniprot.org/uniprot/S8EUW8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_214320 ^@ http://purl.uniprot.org/uniprot/A0A125YKB1 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/508771:TGME49_230690 ^@ http://purl.uniprot.org/uniprot/S8F688 ^@ Similarity ^@ Belongs to the lipin family. http://togogenome.org/gene/508771:TGME49_214350 ^@ http://purl.uniprot.org/uniprot/A0A125YQA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.|||Cytoplasm|||Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.|||Monomer. http://togogenome.org/gene/508771:TGME49_234670 ^@ http://purl.uniprot.org/uniprot/S8GEC2 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/508771:TGME49_255500 ^@ http://purl.uniprot.org/uniprot/A0A125YG21 ^@ Similarity ^@ Belongs to the IFT56 family. http://togogenome.org/gene/508771:TGME49_221950 ^@ http://purl.uniprot.org/uniprot/A0A125YUB5 ^@ Similarity ^@ Belongs to the SF3A3 family. http://togogenome.org/gene/508771:TGME49_262940 ^@ http://purl.uniprot.org/uniprot/A0A125YH51 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/508771:TGME49_200350 ^@ http://purl.uniprot.org/uniprot/S8F3Z4 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/508771:TGME49_248480 ^@ http://purl.uniprot.org/uniprot/A0A125YWF6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/508771:TGME49_230920 ^@ http://purl.uniprot.org/uniprot/A0A125YFX8 ^@ Subcellular Location Annotation ^@ Cell membrane|||coated pit http://togogenome.org/gene/508771:TGME49_299180 ^@ http://purl.uniprot.org/uniprot/A0A125YR27 ^@ Similarity ^@ Belongs to the synaptobrevin family. http://togogenome.org/gene/508771:TGME49_305750 ^@ http://purl.uniprot.org/uniprot/S8GG35 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.|||GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.|||nucleolus http://togogenome.org/gene/508771:TGME49_214090 ^@ http://purl.uniprot.org/uniprot/S8EZH5 ^@ Similarity ^@ Belongs to the NEMF family. http://togogenome.org/gene/508771:TGME49_280400 ^@ http://purl.uniprot.org/uniprot/A0A125YSP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dpy-19 family.|||Membrane http://togogenome.org/gene/508771:TGME49_203830 ^@ http://purl.uniprot.org/uniprot/S8GND7 ^@ Similarity ^@ Belongs to the CHFR family. http://togogenome.org/gene/508771:TGME49_289670 ^@ http://purl.uniprot.org/uniprot/A0A125YI10 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_257080 ^@ http://purl.uniprot.org/uniprot/S8GL35 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_270270 ^@ http://purl.uniprot.org/uniprot/S8EYA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PER33/POM33 family.|||Membrane http://togogenome.org/gene/508771:TGME49_276140 ^@ http://purl.uniprot.org/uniprot/S8GTP2 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/508771:TGME49_280470 ^@ http://purl.uniprot.org/uniprot/A0A125YT56 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_294800 ^@ http://purl.uniprot.org/uniprot/A0A125YKL3 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/508771:TGME49_273500 ^@ http://purl.uniprot.org/uniprot/A0A125YQJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.|||Nucleus http://togogenome.org/gene/508771:TGME49_228000 ^@ http://purl.uniprot.org/uniprot/A0A125YVB0 ^@ Similarity ^@ Belongs to the SF3A2 family. http://togogenome.org/gene/508771:TGME49_290190 ^@ http://purl.uniprot.org/uniprot/S8EX36 ^@ Similarity ^@ Belongs to the SPT2 family. http://togogenome.org/gene/508771:TGME49_314500 ^@ http://purl.uniprot.org/uniprot/A0A125YTZ4 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/508771:TGME49_293590 ^@ http://purl.uniprot.org/uniprot/A0A125YFZ8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/508771:TGME49_290040 ^@ http://purl.uniprot.org/uniprot/A0A125YP71 ^@ Similarity ^@ Belongs to the MIF family. http://togogenome.org/gene/508771:TGME49_288520 ^@ http://purl.uniprot.org/uniprot/S8EWQ6 ^@ Similarity ^@ Belongs to the AAA ATPase family. PCH2 subfamily. http://togogenome.org/gene/508771:TGME49_257980 ^@ http://purl.uniprot.org/uniprot/S8F730 ^@ Similarity ^@ Belongs to the RRF family. http://togogenome.org/gene/508771:TGME49_290180 ^@ http://purl.uniprot.org/uniprot/S8G8E7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_301370 ^@ http://purl.uniprot.org/uniprot/A0A125YR08 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/508771:TGME49_309040 ^@ http://purl.uniprot.org/uniprot/A0A125YYI2 ^@ Similarity ^@ Belongs to the SLBP family. http://togogenome.org/gene/508771:TGME49_278270 ^@ http://purl.uniprot.org/uniprot/A0A125YM52 ^@ Similarity ^@ Belongs to the NOP10 family. http://togogenome.org/gene/508771:TGME49_225490 ^@ http://purl.uniprot.org/uniprot/S8EXE8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_291850 ^@ http://purl.uniprot.org/uniprot/A0A125YL32 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS30 family. http://togogenome.org/gene/508771:TGME49_252420 ^@ http://purl.uniprot.org/uniprot/S8FDT9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_201380 ^@ http://purl.uniprot.org/uniprot/S8F9P4 ^@ Similarity ^@ Belongs to the chorismate synthase family. http://togogenome.org/gene/508771:TGME49_286060 ^@ http://purl.uniprot.org/uniprot/S8F8H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Membrane http://togogenome.org/gene/508771:TGME49_244420 ^@ http://purl.uniprot.org/uniprot/S8GFE4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with 90S and pre-40S pre-ribosomal particles.|||Belongs to the RRP36 family.|||Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.|||nucleolus http://togogenome.org/gene/508771:TGME49_229650 ^@ http://purl.uniprot.org/uniprot/A0A125YQX4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_233710 ^@ http://purl.uniprot.org/uniprot/S8GAE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_228120 ^@ http://purl.uniprot.org/uniprot/S8GFS8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_309120 ^@ http://purl.uniprot.org/uniprot/S8ESF3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL4 family. http://togogenome.org/gene/508771:TGME49_314710 ^@ http://purl.uniprot.org/uniprot/S8GBV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_285180 ^@ http://purl.uniprot.org/uniprot/A0A125YR52 ^@ Similarity ^@ Belongs to the nuclease type I family. http://togogenome.org/gene/508771:TGME49_215740 ^@ http://purl.uniprot.org/uniprot/S8G472 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/508771:TGME49_270370 ^@ http://purl.uniprot.org/uniprot/A0A125YKN1 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/508771:TGME49_210360 ^@ http://purl.uniprot.org/uniprot/A0A125YWJ2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX41 subfamily. http://togogenome.org/gene/508771:TGME49_253290 ^@ http://purl.uniprot.org/uniprot/S8FAP5 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_320460 ^@ http://purl.uniprot.org/uniprot/S8FD11 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_207590 ^@ http://purl.uniprot.org/uniprot/S8FC78 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/508771:TGME49_231060 ^@ http://purl.uniprot.org/uniprot/S8GKC1 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/508771:TGME49_262070 ^@ http://purl.uniprot.org/uniprot/A0A125YI24 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KRR1 family.|||Component of the ribosomal small subunit (SSU) processome.|||Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.|||nucleolus http://togogenome.org/gene/508771:TGME49_321290 ^@ http://purl.uniprot.org/uniprot/A0A125YI37 ^@ Similarity ^@ Belongs to the PRP18 family. http://togogenome.org/gene/508771:TGME49_217480 ^@ http://purl.uniprot.org/uniprot/A0A125YJJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family.|||Nucleus http://togogenome.org/gene/508771:TGME49_207900 ^@ http://purl.uniprot.org/uniprot/S8GKS0 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/508771:TGME49_218610 ^@ http://purl.uniprot.org/uniprot/S8EUM7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.|||nucleolus http://togogenome.org/gene/508771:TGME49_292055 ^@ http://purl.uniprot.org/uniprot/S8F0H0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_278280 ^@ http://purl.uniprot.org/uniprot/S8EPV3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_278110 ^@ http://purl.uniprot.org/uniprot/S8ESW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 48 family.|||Membrane http://togogenome.org/gene/508771:TGME49_230860 ^@ http://purl.uniprot.org/uniprot/A0A125YY16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATG5 family.|||Conjugated with ATG12.|||Involved in autophagic vesicle formation.|||Preautophagosomal structure membrane http://togogenome.org/gene/508771:TGME49_249330 ^@ http://purl.uniprot.org/uniprot/A0A125YHG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERCC1/RAD10/SWI10 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_314280 ^@ http://purl.uniprot.org/uniprot/A0A125YH74 ^@ Similarity ^@ Belongs to the AAR2 family. http://togogenome.org/gene/508771:TGME49_207990 ^@ http://purl.uniprot.org/uniprot/S8GUX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.|||Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.|||nucleolus http://togogenome.org/gene/508771:TGME49_290260 ^@ http://purl.uniprot.org/uniprot/S8F052 ^@ Similarity ^@ Belongs to the PITHD1 family. http://togogenome.org/gene/508771:TGME49_268890 ^@ http://purl.uniprot.org/uniprot/S8GIJ1 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/508771:TGME49_266990 ^@ http://purl.uniprot.org/uniprot/S8GGL3 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/508771:TGME49_223672 ^@ http://purl.uniprot.org/uniprot/S8GEN4 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. CysQ family. http://togogenome.org/gene/508771:TGME49_278230 ^@ http://purl.uniprot.org/uniprot/A0A125YG60 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit beta family. http://togogenome.org/gene/508771:TGME49_319620 ^@ http://purl.uniprot.org/uniprot/A0A125YV75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_261250 ^@ http://purl.uniprot.org/uniprot/A0A125YX75 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/508771:TGME49_266310 ^@ http://purl.uniprot.org/uniprot/S8F2D0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 13 family.|||Membrane http://togogenome.org/gene/508771:TGME49_203050 ^@ http://purl.uniprot.org/uniprot/S8F2Z9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_254620 ^@ http://purl.uniprot.org/uniprot/A0A125YT88 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL39 family. http://togogenome.org/gene/508771:TGME49_233130 ^@ http://purl.uniprot.org/uniprot/A0A125YYW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/508771:TGME49_251760 ^@ http://purl.uniprot.org/uniprot/A0A125YQR3 ^@ Similarity ^@ Belongs to the PA28 family. http://togogenome.org/gene/508771:TGME49_207060 ^@ http://purl.uniprot.org/uniprot/A0A125YW11 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/508771:TGME49_205350 ^@ http://purl.uniprot.org/uniprot/A0A125YTU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/508771:TGME49_207910 ^@ http://purl.uniprot.org/uniprot/S8GUY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.|||Membrane http://togogenome.org/gene/508771:TGME49_233860 ^@ http://purl.uniprot.org/uniprot/S8EZ47 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_285760 ^@ http://purl.uniprot.org/uniprot/A0A125YL73 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/508771:TGME49_223620 ^@ http://purl.uniprot.org/uniprot/A0A125YTL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_212200 ^@ http://purl.uniprot.org/uniprot/A0A125YGL8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_277990 ^@ http://purl.uniprot.org/uniprot/S8ESW9 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. http://togogenome.org/gene/508771:TGME49_230200 ^@ http://purl.uniprot.org/uniprot/S8GB43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CFAP206 family.|||cilium axoneme http://togogenome.org/gene/508771:TGME49_311500 ^@ http://purl.uniprot.org/uniprot/S8EUP0 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. http://togogenome.org/gene/508771:TGME49_311310 ^@ http://purl.uniprot.org/uniprot/A0A125YWN8 ^@ Similarity ^@ Belongs to the PPP phosphatase family. PP-2B subfamily. http://togogenome.org/gene/508771:TGME49_209940 ^@ http://purl.uniprot.org/uniprot/S8GK87 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_211450 ^@ http://purl.uniprot.org/uniprot/A0A125YYR9 ^@ Similarity ^@ Belongs to the tRNA pseudouridine synthase TruA family. http://togogenome.org/gene/508771:TGME49_203720 ^@ http://purl.uniprot.org/uniprot/A0A125YRZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_273520 ^@ http://purl.uniprot.org/uniprot/A0A125YQR2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit E family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_209650 ^@ http://purl.uniprot.org/uniprot/S8FBR2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the reverse transcriptase family. Telomerase subfamily.|||Nucleus|||Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.|||telomere http://togogenome.org/gene/508771:TGME49_219700 ^@ http://purl.uniprot.org/uniprot/S8EMY3 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/508771:TGME49_266940 ^@ http://purl.uniprot.org/uniprot/S8G7A3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_306000 ^@ http://purl.uniprot.org/uniprot/S8EVH8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_280490 ^@ http://purl.uniprot.org/uniprot/A0A125YQ09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin conjugation factor E4 family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_306970 ^@ http://purl.uniprot.org/uniprot/A0A125YT91 ^@ Similarity ^@ Belongs to the thymidylate kinase family. http://togogenome.org/gene/508771:TGME49_210750 ^@ http://purl.uniprot.org/uniprot/A0A125YNX0 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_286070 ^@ http://purl.uniprot.org/uniprot/A0A125YRB6 ^@ Similarity ^@ Belongs to the PET191 family. http://togogenome.org/gene/508771:TGME49_211480 ^@ http://purl.uniprot.org/uniprot/A0A125YXC6 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. http://togogenome.org/gene/508771:TGME49_266100 ^@ http://purl.uniprot.org/uniprot/S8G7G8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_294290 ^@ http://purl.uniprot.org/uniprot/A0A125YKE4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/508771:TGME49_288450 ^@ http://purl.uniprot.org/uniprot/S8GHC6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/508771:TGME49_202460 ^@ http://purl.uniprot.org/uniprot/S8GEF4 ^@ Similarity ^@ Belongs to the eukaryotic diacylglycerol kinase family. http://togogenome.org/gene/508771:TGME49_216880 ^@ http://purl.uniprot.org/uniprot/A0A125YYS0 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily. http://togogenome.org/gene/508771:TGME49_208420 ^@ http://purl.uniprot.org/uniprot/A0A125YRX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_295330 ^@ http://purl.uniprot.org/uniprot/A0A125YWN3 ^@ Similarity ^@ Belongs to the VPS54 family. http://togogenome.org/gene/508771:TGME49_209000 ^@ http://purl.uniprot.org/uniprot/S8FEZ8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_207720 ^@ http://purl.uniprot.org/uniprot/S8GKT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NRAP family.|||nucleolus http://togogenome.org/gene/508771:TGME49_289530 ^@ http://purl.uniprot.org/uniprot/A0A125YMW1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL19 family. http://togogenome.org/gene/508771:TGME49_285530 ^@ http://purl.uniprot.org/uniprot/S8GGV7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/508771:TGME49_239930 ^@ http://purl.uniprot.org/uniprot/A0A125YM78 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_261580 ^@ http://purl.uniprot.org/uniprot/A0A125YFR3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/508771:TGME49_305780 ^@ http://purl.uniprot.org/uniprot/S8EYJ2 ^@ Similarity ^@ Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily. http://togogenome.org/gene/508771:TGME49_230230 ^@ http://purl.uniprot.org/uniprot/S8F031 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FIP1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_254050 ^@ http://purl.uniprot.org/uniprot/A0A125YG82 ^@ Similarity ^@ Belongs to the OPA3 family. http://togogenome.org/gene/508771:TGME49_247500 ^@ http://purl.uniprot.org/uniprot/A0A125YQU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-CoA oxidase family.|||Peroxisome http://togogenome.org/gene/508771:TGME49_288290 ^@ http://purl.uniprot.org/uniprot/S8EWP1 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family. http://togogenome.org/gene/508771:TGME49_233040 ^@ http://purl.uniprot.org/uniprot/A0A125YY11 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/508771:TGME49_306590 ^@ http://purl.uniprot.org/uniprot/S8GG85 ^@ Similarity ^@ Belongs to the MIP18 family. http://togogenome.org/gene/508771:TGME49_231420 ^@ http://purl.uniprot.org/uniprot/A0A125YK02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/508771:TGME49_267060 ^@ http://purl.uniprot.org/uniprot/A0A125YYV8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL14 family. http://togogenome.org/gene/508771:TGME49_214830 ^@ http://purl.uniprot.org/uniprot/S8G4D8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Cytoplasm|||Nucleus|||tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. http://togogenome.org/gene/508771:TGME49_256060 ^@ http://purl.uniprot.org/uniprot/S8GBJ8 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/508771:TGME49_315360 ^@ http://purl.uniprot.org/uniprot/A0A125YSY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the INCENP family.|||Nucleus|||spindle http://togogenome.org/gene/508771:TGME49_203030 ^@ http://purl.uniprot.org/uniprot/S8GNM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_314780 ^@ http://purl.uniprot.org/uniprot/A0A125YV37 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/508771:TGME49_257510 ^@ http://purl.uniprot.org/uniprot/A0A125YG25 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/508771:TGME49_291600 ^@ http://purl.uniprot.org/uniprot/S8EXA3 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/508771:TGME49_256970 ^@ http://purl.uniprot.org/uniprot/A0A125YNI8 ^@ Similarity ^@ Belongs to the ATPase alpha/beta chains family. http://togogenome.org/gene/508771:TGME49_261560 ^@ http://purl.uniprot.org/uniprot/S8GCP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HOP2 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_209910 ^@ http://purl.uniprot.org/uniprot/A0A125YMF5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/508771:TGME49_228710 ^@ http://purl.uniprot.org/uniprot/S8F1K5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_237500 ^@ http://purl.uniprot.org/uniprot/S8ET53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Enzyme with a broad specificity.|||Membrane http://togogenome.org/gene/508771:TGME49_273290 ^@ http://purl.uniprot.org/uniprot/S8GA35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/508771:TGME49_202572 ^@ http://purl.uniprot.org/uniprot/S8GNS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OST1 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/508771:TGME49_257110 ^@ http://purl.uniprot.org/uniprot/S8F3L5 ^@ Similarity ^@ Belongs to the peptidase M76 family. http://togogenome.org/gene/508771:TGME49_293580 ^@ http://purl.uniprot.org/uniprot/A0A125YPK5 ^@ Similarity ^@ Belongs to the prefoldin subunit beta family. http://togogenome.org/gene/508771:TGME49_297970 ^@ http://purl.uniprot.org/uniprot/A0A125YW18 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/508771:TGME49_291080 ^@ http://purl.uniprot.org/uniprot/A0A125YP75 ^@ Similarity ^@ Belongs to the TBP family. http://togogenome.org/gene/508771:TGME49_201840 ^@ http://purl.uniprot.org/uniprot/S8F3D0 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/508771:TGME49_239748 ^@ http://purl.uniprot.org/uniprot/S8GG22 ^@ Similarity ^@ Belongs to the PIGH family. http://togogenome.org/gene/508771:TGME49_259140 ^@ http://purl.uniprot.org/uniprot/A0A125YHD1 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/508771:TGME49_289230 ^@ http://purl.uniprot.org/uniprot/S8EWV6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL12 family. http://togogenome.org/gene/508771:TGME49_268720 ^@ http://purl.uniprot.org/uniprot/S8G926 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIF1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_227290 ^@ http://purl.uniprot.org/uniprot/A0A125YPH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone deacetylase family. HD Type 1 subfamily.|||Nucleus http://togogenome.org/gene/508771:TGME49_244520 ^@ http://purl.uniprot.org/uniprot/S8F442 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_248670 ^@ http://purl.uniprot.org/uniprot/A0A125YR49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_202800 ^@ http://purl.uniprot.org/uniprot/S8F980 ^@ Function|||Subcellular Location Annotation ^@ Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_207450 ^@ http://purl.uniprot.org/uniprot/A0A125YNQ5 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Catalytic component of the tRNA-splicing ligase complex.|||Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.|||Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP. http://togogenome.org/gene/508771:TGME49_311220 ^@ http://purl.uniprot.org/uniprot/S8ERU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_265040 ^@ http://purl.uniprot.org/uniprot/A0A125YTS2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_284580 ^@ http://purl.uniprot.org/uniprot/S8GQU3 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/508771:TGME49_219860 ^@ http://purl.uniprot.org/uniprot/S8EUC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/508771:TGME49_254555 ^@ http://purl.uniprot.org/uniprot/S8GIK3 ^@ Similarity ^@ Belongs to the acetyltransferase family. GCN5 subfamily. http://togogenome.org/gene/508771:TGME49_233760 ^@ http://purl.uniprot.org/uniprot/S8F2A3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_278740 ^@ http://purl.uniprot.org/uniprot/S8EW98 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/508771:TGME49_316660 ^@ http://purl.uniprot.org/uniprot/A0A125YRJ1 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/508771:TGME49_249180 ^@ http://purl.uniprot.org/uniprot/A0A125YXY3 ^@ Function|||Similarity ^@ Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP.|||In the C-terminal section; belongs to the thymidylate synthase family.|||In the N-terminal section; belongs to the dihydrofolate reductase family. http://togogenome.org/gene/508771:TGME49_315760 ^@ http://purl.uniprot.org/uniprot/A0A125YUE1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_246000 ^@ http://purl.uniprot.org/uniprot/A0A125YX92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL49 family.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_219260 ^@ http://purl.uniprot.org/uniprot/S8G8M6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.|||Membrane http://togogenome.org/gene/508771:TGME49_280610 ^@ http://purl.uniprot.org/uniprot/A0A125YKT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_229670 ^@ http://purl.uniprot.org/uniprot/A0A125YRX2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS12 family. http://togogenome.org/gene/508771:TGME49_243210 ^@ http://purl.uniprot.org/uniprot/A0A125YI58 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/508771:TGME49_314860 ^@ http://purl.uniprot.org/uniprot/A0A125YN08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BBP/SF1 family.|||Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.|||Nucleus http://togogenome.org/gene/508771:TGME49_239690 ^@ http://purl.uniprot.org/uniprot/A0A125YRY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC6 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_205670 ^@ http://purl.uniprot.org/uniprot/A0A125YS14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF-assemblin family.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_216890 ^@ http://purl.uniprot.org/uniprot/S8GB98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_244380 ^@ http://purl.uniprot.org/uniprot/S8GPP8 ^@ Similarity ^@ Belongs to the CACTIN family. http://togogenome.org/gene/508771:TGME49_274080 ^@ http://purl.uniprot.org/uniprot/S8GAA7 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/508771:TGME49_236010 ^@ http://purl.uniprot.org/uniprot/S8ETF6 ^@ Similarity ^@ Belongs to the prenylcysteine oxidase family. http://togogenome.org/gene/508771:TGME49_313450 ^@ http://purl.uniprot.org/uniprot/A0A125YFX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cell membrane|||coated pit http://togogenome.org/gene/508771:TGME49_310350 ^@ http://purl.uniprot.org/uniprot/S8G3I4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI inositol-deacylase family.|||Endoplasmic reticulum membrane|||Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. http://togogenome.org/gene/508771:TGME49_263510 ^@ http://purl.uniprot.org/uniprot/S8GD76 ^@ Similarity ^@ Belongs to the TUBGCP family. http://togogenome.org/gene/508771:TGME49_305620 ^@ http://purl.uniprot.org/uniprot/S8G6S9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RFT1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_244000 ^@ http://purl.uniprot.org/uniprot/S8GPL4 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/508771:TGME49_212240 ^@ http://purl.uniprot.org/uniprot/A0A125YJU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/508771:TGME49_291820 ^@ http://purl.uniprot.org/uniprot/S8F0E9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA2/NAM7 helicase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_227840 ^@ http://purl.uniprot.org/uniprot/A0A125YPK9 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/508771:TGME49_261540 ^@ http://purl.uniprot.org/uniprot/A0A125YT58 ^@ Similarity ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family. http://togogenome.org/gene/508771:TGME49_223050 ^@ http://purl.uniprot.org/uniprot/A0A125YYM8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS10 family. http://togogenome.org/gene/508771:TGME49_249020 ^@ http://purl.uniprot.org/uniprot/S8G0K1 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_243710 ^@ http://purl.uniprot.org/uniprot/A0A125YLE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_301440 ^@ http://purl.uniprot.org/uniprot/A0A125YH30 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_268810 ^@ http://purl.uniprot.org/uniprot/A0A125YK54 ^@ Similarity|||Subunit ^@ Belongs to the casein kinase 2 subunit beta family.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/508771:TGME49_299200 ^@ http://purl.uniprot.org/uniprot/A0A125YTG8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Homodimer.|||May play a role in vesicular transport from endoplasmic reticulum to Golgi.|||cis-Golgi network http://togogenome.org/gene/508771:TGME49_264200 ^@ http://purl.uniprot.org/uniprot/S8F578 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/508771:TGME49_226420 ^@ http://purl.uniprot.org/uniprot/S8EXL9 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/508771:TGME49_273560 ^@ http://purl.uniprot.org/uniprot/A0A125YU28 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_216380 ^@ http://purl.uniprot.org/uniprot/A0A125YXJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/508771:TGME49_309950 ^@ http://purl.uniprot.org/uniprot/S8EYN2 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/508771:TGME49_233110 ^@ http://purl.uniprot.org/uniprot/A0A125YHW6 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/508771:TGME49_263060 ^@ http://purl.uniprot.org/uniprot/S8F830 ^@ Similarity ^@ Belongs to the proteasome subunit S1 family. http://togogenome.org/gene/508771:TGME49_219760 ^@ http://purl.uniprot.org/uniprot/S8G8J1 ^@ Similarity ^@ Belongs to the acetyltransferase family. ARD1 subfamily. http://togogenome.org/gene/508771:TGME49_234540 ^@ http://purl.uniprot.org/uniprot/S8GED0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_227650 ^@ http://purl.uniprot.org/uniprot/S8G6B6 ^@ Similarity ^@ Belongs to the MAPRE family. http://togogenome.org/gene/508771:TGME49_243490 ^@ http://purl.uniprot.org/uniprot/S8F6Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family. BCS1 subfamily.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_259250 ^@ http://purl.uniprot.org/uniprot/S8F444 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family. RecQ subfamily.|||Nucleus http://togogenome.org/gene/508771:TGME49_242600 ^@ http://purl.uniprot.org/uniprot/A0A125YV48 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/508771:TGME49_256770 ^@ http://purl.uniprot.org/uniprot/A0A125YSV6 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/508771:TGME49_294670 ^@ http://purl.uniprot.org/uniprot/A0A125YLN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit G family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. http://togogenome.org/gene/508771:TGME49_270560 ^@ http://purl.uniprot.org/uniprot/A0A125YV51 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/508771:TGME49_239080 ^@ http://purl.uniprot.org/uniprot/A0A125YS45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_222010 ^@ http://purl.uniprot.org/uniprot/S8F823 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_305290 ^@ http://purl.uniprot.org/uniprot/S8EVC9 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/508771:TGME49_273360 ^@ http://purl.uniprot.org/uniprot/A0A125YNQ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_289940 ^@ http://purl.uniprot.org/uniprot/S8G8D4 ^@ Similarity|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Homodimer. http://togogenome.org/gene/508771:TGME49_238940 ^@ http://purl.uniprot.org/uniprot/S8F7X1 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. http://togogenome.org/gene/508771:TGME49_212740 ^@ http://purl.uniprot.org/uniprot/S8FBW5 ^@ Similarity ^@ Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. http://togogenome.org/gene/508771:TGME49_239490 ^@ http://purl.uniprot.org/uniprot/S8GG59 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/508771:TGME49_251870 ^@ http://purl.uniprot.org/uniprot/A0A125YW38 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/508771:TGME49_220860 ^@ http://purl.uniprot.org/uniprot/A0A125YVU3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/508771:TGME49_211350 ^@ http://purl.uniprot.org/uniprot/A0A125YWU7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_318580 ^@ http://purl.uniprot.org/uniprot/S8GS96 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/508771:TGME49_203460 ^@ http://purl.uniprot.org/uniprot/S8F5X9 ^@ Similarity ^@ Belongs to the TRIAP1/MDM35 family. http://togogenome.org/gene/508771:TGME49_239020 ^@ http://purl.uniprot.org/uniprot/A0A125YIS0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_316360 ^@ http://purl.uniprot.org/uniprot/A0A125YPM5 ^@ Similarity ^@ Belongs to the profilin family. http://togogenome.org/gene/508771:TGME49_217692 ^@ http://purl.uniprot.org/uniprot/S8G902 ^@ Similarity ^@ Belongs to the glycosyltransferase 47 family. http://togogenome.org/gene/508771:TGME49_255740 ^@ http://purl.uniprot.org/uniprot/S8F3E3 ^@ Similarity ^@ Belongs to the RPAP2 family. http://togogenome.org/gene/508771:TGME49_247550 ^@ http://purl.uniprot.org/uniprot/A0A125YNH2 ^@ Similarity ^@ Belongs to the chaperonin (HSP60) family. http://togogenome.org/gene/508771:TGME49_216250 ^@ http://purl.uniprot.org/uniprot/A0A125YPN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC5 subfamily.|||Nucleus http://togogenome.org/gene/508771:TGME49_292100 ^@ http://purl.uniprot.org/uniprot/A0A125YGH1 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/508771:TGME49_248340 ^@ http://purl.uniprot.org/uniprot/A0A125YV46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Ran family.|||GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.|||Nucleus http://togogenome.org/gene/508771:TGME49_289210 ^@ http://purl.uniprot.org/uniprot/S8EZX0 ^@ Similarity ^@ Belongs to the prefoldin subunit beta family. http://togogenome.org/gene/508771:TGME49_297720 ^@ http://purl.uniprot.org/uniprot/S8FBG9 ^@ Similarity ^@ In the C-terminal section; belongs to the trehalose phosphatase family.|||In the N-terminal section; belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/508771:TGME49_259172 ^@ http://purl.uniprot.org/uniprot/S8F7B2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GLE1 family.|||nuclear pore complex http://togogenome.org/gene/508771:TGME49_290170 ^@ http://purl.uniprot.org/uniprot/S8GHS2 ^@ Similarity ^@ Belongs to the PPP phosphatase family. BSU subfamily. http://togogenome.org/gene/508771:TGME49_266800 ^@ http://purl.uniprot.org/uniprot/A0A125YL81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCC1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_301120 ^@ http://purl.uniprot.org/uniprot/A0A125YTZ3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/508771:TGME49_231120 ^@ http://purl.uniprot.org/uniprot/S8F665 ^@ Subcellular Location Annotation ^@ chloroplast http://togogenome.org/gene/508771:TGME49_305920 ^@ http://purl.uniprot.org/uniprot/S8G6U3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Nth/MutY family.|||Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.|||Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.|||Mitochondrion|||Nucleus http://togogenome.org/gene/508771:TGME49_294720 ^@ http://purl.uniprot.org/uniprot/S8FFF9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_257720 ^@ http://purl.uniprot.org/uniprot/S8F3S6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_230100 ^@ http://purl.uniprot.org/uniprot/A0A125YFK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC3 family.|||Membrane http://togogenome.org/gene/508771:TGME49_293570 ^@ http://purl.uniprot.org/uniprot/S8GVG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC62 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_223490 ^@ http://purl.uniprot.org/uniprot/S8G5F3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_285240 ^@ http://purl.uniprot.org/uniprot/S8F509 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family.|||Membrane http://togogenome.org/gene/508771:TGME49_263130 ^@ http://purl.uniprot.org/uniprot/A0A125YJE0 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/508771:TGME49_310060 ^@ http://purl.uniprot.org/uniprot/A0A125YIE6 ^@ Similarity ^@ Belongs to the oligoribonuclease family. http://togogenome.org/gene/508771:TGME49_224580 ^@ http://purl.uniprot.org/uniprot/S8EX69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF3B4 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_225080 ^@ http://purl.uniprot.org/uniprot/A0A125YQU0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS13 family. http://togogenome.org/gene/508771:TGME49_237480 ^@ http://purl.uniprot.org/uniprot/S8EZI0 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/508771:TGME49_276180 ^@ http://purl.uniprot.org/uniprot/S8FAV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_312680 ^@ http://purl.uniprot.org/uniprot/A0A125YTD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL41 family.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_318190 ^@ http://purl.uniprot.org/uniprot/A0A125YR40 ^@ Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. http://togogenome.org/gene/508771:TGME49_276190 ^@ http://purl.uniprot.org/uniprot/S8FDX8 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/508771:TGME49_203610 ^@ http://purl.uniprot.org/uniprot/S8F921 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_257010 ^@ http://purl.uniprot.org/uniprot/S8F3K3 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/508771:TGME49_210790 ^@ http://purl.uniprot.org/uniprot/A0A125YJK1 ^@ Similarity ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. http://togogenome.org/gene/508771:TGME49_225240 ^@ http://purl.uniprot.org/uniprot/A0A125YJY5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/508771:TGME49_282210 ^@ http://purl.uniprot.org/uniprot/S8GP85 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_224310 ^@ http://purl.uniprot.org/uniprot/S8EU53 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/508771:TGME49_226030 ^@ http://purl.uniprot.org/uniprot/A0A125YVN4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/508771:TGME49_239710 ^@ http://purl.uniprot.org/uniprot/A0A125YGJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic PMM family.|||Cytoplasm|||Homodimer.|||Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. http://togogenome.org/gene/508771:TGME49_306520 ^@ http://purl.uniprot.org/uniprot/A0A125YGW0 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruB family. http://togogenome.org/gene/508771:TGME49_231170 ^@ http://purl.uniprot.org/uniprot/S8F2V2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family.|||Nucleus http://togogenome.org/gene/508771:TGME49_320050 ^@ http://purl.uniprot.org/uniprot/A0A125YYH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uL18 family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_297230 ^@ http://purl.uniprot.org/uniprot/S8FBD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS53 family.|||Endosome membrane|||Membrane|||trans-Golgi network membrane http://togogenome.org/gene/508771:TGME49_312090 ^@ http://purl.uniprot.org/uniprot/A0A125YJR7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/508771:TGME49_239530 ^@ http://purl.uniprot.org/uniprot/S8F4R6 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/508771:TGME49_261380 ^@ http://purl.uniprot.org/uniprot/A0A125YNF6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS8 family. http://togogenome.org/gene/508771:TGME49_218410 ^@ http://purl.uniprot.org/uniprot/A0A125YFP1 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL10 family.|||Ribosomal protein P0 is the functional equivalent of E.coli protein L10. http://togogenome.org/gene/508771:TGME49_262690 ^@ http://purl.uniprot.org/uniprot/S8F1P5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL27 family. http://togogenome.org/gene/508771:TGME49_215440 ^@ http://purl.uniprot.org/uniprot/S8EZB0 ^@ Similarity ^@ Belongs to the Deltex family. http://togogenome.org/gene/508771:TGME49_233350 ^@ http://purl.uniprot.org/uniprot/A0A125YLB7 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/508771:TGME49_208070 ^@ http://purl.uniprot.org/uniprot/S8FF35 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/508771:TGME49_242660 ^@ http://purl.uniprot.org/uniprot/A0A125YH52 ^@ Function|||Similarity ^@ Belongs to the VPS35 family.|||Plays a role in vesicular protein sorting. http://togogenome.org/gene/508771:TGME49_261570 ^@ http://purl.uniprot.org/uniprot/A0A125YW75 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Component of the ribosome. http://togogenome.org/gene/508771:TGME49_229310 ^@ http://purl.uniprot.org/uniprot/S8F094 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 14 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/508771:TGME49_315260 ^@ http://purl.uniprot.org/uniprot/A0A125YPR3 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/508771:TGME49_240290 ^@ http://purl.uniprot.org/uniprot/S8FAM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the flagellar radial spoke RSP3 family.|||flagellum axoneme http://togogenome.org/gene/508771:TGME49_227970 ^@ http://purl.uniprot.org/uniprot/S8F1A0 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/508771:TGME49_291170 ^@ http://purl.uniprot.org/uniprot/S8EX95 ^@ Similarity ^@ Belongs to the IST1 family. http://togogenome.org/gene/508771:TGME49_256020 ^@ http://purl.uniprot.org/uniprot/S8GKY7 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/508771:TGME49_255620 ^@ http://purl.uniprot.org/uniprot/S8GBG5 ^@ Subcellular Location Annotation ^@ cilium basal body http://togogenome.org/gene/508771:TGME49_253420 ^@ http://purl.uniprot.org/uniprot/S8GTD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_270450 ^@ http://purl.uniprot.org/uniprot/S8G9K0 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/508771:TGME49_314430 ^@ http://purl.uniprot.org/uniprot/A0A125YZF0 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily. http://togogenome.org/gene/508771:TGME49_251680 ^@ http://purl.uniprot.org/uniprot/A0A125YGX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCTP family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_259000 ^@ http://purl.uniprot.org/uniprot/A0A125YWT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC4 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_249590 ^@ http://purl.uniprot.org/uniprot/A0A125YVM9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/508771:TGME49_232180 ^@ http://purl.uniprot.org/uniprot/S8F601 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGS family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_283500 ^@ http://purl.uniprot.org/uniprot/S8F885 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TTC30/dfy-1/fleer family.|||cilium http://togogenome.org/gene/508771:TGME49_248320 ^@ http://purl.uniprot.org/uniprot/A0A125YYN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_234410 ^@ http://purl.uniprot.org/uniprot/S8EWM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/508771:TGME49_238240 ^@ http://purl.uniprot.org/uniprot/A0A125YTA8 ^@ Similarity ^@ Belongs to the bystin family. http://togogenome.org/gene/508771:TGME49_258710 ^@ http://purl.uniprot.org/uniprot/S8GC27 ^@ Similarity ^@ Belongs to the TCP10 family. http://togogenome.org/gene/508771:TGME49_221410 ^@ http://purl.uniprot.org/uniprot/S8F7W8 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/508771:TGME49_213030 ^@ http://purl.uniprot.org/uniprot/A0A125YZ92 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the clathrin light chain family.|||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.|||Cytoplasmic vesicle membrane|||coated pit http://togogenome.org/gene/508771:TGME49_285690 ^@ http://purl.uniprot.org/uniprot/S8FBP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_253520 ^@ http://purl.uniprot.org/uniprot/S8GIZ1 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/508771:TGME49_237890 ^@ http://purl.uniprot.org/uniprot/A0A125YGJ8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/508771:TGME49_225880 ^@ http://purl.uniprot.org/uniprot/A0A125YPT3 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/508771:TGME49_319600 ^@ http://purl.uniprot.org/uniprot/A0A125YWW9 ^@ Function|||Similarity ^@ Belongs to the acetyltransferase ATAT1 family.|||Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. http://togogenome.org/gene/508771:TGME49_244180 ^@ http://purl.uniprot.org/uniprot/S8GFC0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_246100 ^@ http://purl.uniprot.org/uniprot/A0A125YW87 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/508771:TGME49_320140 ^@ http://purl.uniprot.org/uniprot/A0A125YU99 ^@ Similarity ^@ Belongs to the UQCRH/QCR6 family. http://togogenome.org/gene/508771:TGME49_215090 ^@ http://purl.uniprot.org/uniprot/S8GDH4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/508771:TGME49_300320 ^@ http://purl.uniprot.org/uniprot/S8EQ26 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/508771:TGME49_239560 ^@ http://purl.uniprot.org/uniprot/A0A125YIV9 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/508771:TGME49_236080 ^@ http://purl.uniprot.org/uniprot/S8G4V7 ^@ Similarity ^@ Belongs to the replication factor A protein 1 family. http://togogenome.org/gene/508771:TGME49_222952 ^@ http://purl.uniprot.org/uniprot/S8F876 ^@ Similarity ^@ Belongs to the janus family. http://togogenome.org/gene/508771:TGME49_233540 ^@ http://purl.uniprot.org/uniprot/S8EZ66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_312990 ^@ http://purl.uniprot.org/uniprot/A0A125YGG5 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/508771:TGME49_304660 ^@ http://purl.uniprot.org/uniprot/A0A125YQ14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GST superfamily.|||Membrane http://togogenome.org/gene/508771:TGME49_264010 ^@ http://purl.uniprot.org/uniprot/S8GDB9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SNUT3 family.|||May play a role in mRNA splicing.|||Nucleus|||Part of a tri-snRNP complex. http://togogenome.org/gene/508771:TGME49_269800 ^@ http://purl.uniprot.org/uniprot/S8G9F6 ^@ Similarity ^@ In the C-terminal section; belongs to the NAD synthetase family. http://togogenome.org/gene/508771:TGME49_275970 ^@ http://purl.uniprot.org/uniprot/A0A125YRJ7 ^@ Similarity ^@ Belongs to the tubulin family. http://togogenome.org/gene/508771:TGME49_207980 ^@ http://purl.uniprot.org/uniprot/A0A125YY92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_239310 ^@ http://purl.uniprot.org/uniprot/S8GQK2 ^@ Similarity ^@ Belongs to the ribose 5-phosphate isomerase family. http://togogenome.org/gene/508771:TGME49_300100 ^@ http://purl.uniprot.org/uniprot/B6KV60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the apicomplexan parasites RON2 family.|||Component of the moving junction (MJ) complex, composed of AMA1, a transmembrane protein on the parasite surface, and a complex of the rhoptry neck proteins RON2, RON4, RON5 and RON8 localized to the cytoplasmic face of the host plasma membrane. Interacts (via C-terminus) with AMA1 (via ectodomain); RON2 serves as the receptor for AMA1 on the host plasma membrane. AMA1 and the RON proteins are initially in distinct compartments within the parasite, namely the micronemes and the rhoptries, and interaction happens only upon initiation of invasion when the micronemes and rhoptries discharge.|||Cytoplasm|||Essential rhoptry neck protein that plays an important role in host cell invasion. Upon host invasion by tachyzoites, the protein is injected into the host cell where it functions as a receptor for apical membrane antigen 1 (AMA1) on the parasite. Part of the moving junction (MJ) complex, a ringlike structure formed between the plasma membranes of the apical tip of the parasite and the target host cell. During invasion, the MJ migrates from the anterior to the posterior of the parasite, leading to internalization of the parasite into a parasitophorous vacuole (PV).|||Host cell membrane|||Secreted http://togogenome.org/gene/508771:TGME49_295720 ^@ http://purl.uniprot.org/uniprot/A0A125YP64 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/508771:TGME49_257440 ^@ http://purl.uniprot.org/uniprot/S8F0Q8 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/508771:TGME49_246560 ^@ http://purl.uniprot.org/uniprot/A0A125YRR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase G subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/508771:TGME49_245570 ^@ http://purl.uniprot.org/uniprot/S8ENF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ORC2 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_258210 ^@ http://purl.uniprot.org/uniprot/A0A125YPG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||apicoplast http://togogenome.org/gene/508771:TGME49_275480 ^@ http://purl.uniprot.org/uniprot/S8GDA5 ^@ Similarity ^@ Belongs to the CEF1 family. http://togogenome.org/gene/508771:TGME49_242890 ^@ http://purl.uniprot.org/uniprot/S8GF32 ^@ Similarity ^@ Belongs to the BLM10 family. http://togogenome.org/gene/508771:TGME49_216630 ^@ http://purl.uniprot.org/uniprot/S8EQA6 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. Tig subfamily. http://togogenome.org/gene/508771:TGME49_286630 ^@ http://purl.uniprot.org/uniprot/A0A125YMB2 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/508771:TGME49_205300 ^@ http://purl.uniprot.org/uniprot/S8GDT7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_311680 ^@ http://purl.uniprot.org/uniprot/A0A125YM24 ^@ Similarity ^@ Belongs to the FUN14 family. http://togogenome.org/gene/508771:TGME49_313670 ^@ http://purl.uniprot.org/uniprot/A0A125YFF4 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/508771:TGME49_249720 ^@ http://purl.uniprot.org/uniprot/A0A125YJV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Membrane http://togogenome.org/gene/508771:TGME49_219550 ^@ http://purl.uniprot.org/uniprot/A0A125YJF1 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/508771:TGME49_235650 ^@ http://purl.uniprot.org/uniprot/S8EZT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Peroxisome membrane http://togogenome.org/gene/508771:TGME49_318570 ^@ http://purl.uniprot.org/uniprot/A0A125YKM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/508771:TGME49_289770 ^@ http://purl.uniprot.org/uniprot/A0A125YND4 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/508771:TGME49_288580 ^@ http://purl.uniprot.org/uniprot/A0A125YYQ1 ^@ Similarity ^@ Belongs to the ANT/ATPSC lysine N-methyltransferase family. http://togogenome.org/gene/508771:TGME49_215700 ^@ http://purl.uniprot.org/uniprot/S8EZ97 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. http://togogenome.org/gene/508771:TGME49_310670 ^@ http://purl.uniprot.org/uniprot/S8EYF4 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/508771:TGME49_288380 ^@ http://purl.uniprot.org/uniprot/A0A125YVB7 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/508771:TGME49_240590 ^@ http://purl.uniprot.org/uniprot/A0A125YNC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/508771:TGME49_313630 ^@ http://purl.uniprot.org/uniprot/S8GC16 ^@ Similarity ^@ Belongs to the VPS13 family. http://togogenome.org/gene/508771:TGME49_287230 ^@ http://purl.uniprot.org/uniprot/S8FBE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_211040 ^@ http://purl.uniprot.org/uniprot/A0A125YP59 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC61-beta family.|||Endoplasmic reticulum membrane|||Membrane|||Necessary for protein translocation in the endoplasmic reticulum. http://togogenome.org/gene/508771:TGME49_287210 ^@ http://purl.uniprot.org/uniprot/A0A125YFE9 ^@ Similarity ^@ Belongs to the peptidase T1A family. http://togogenome.org/gene/508771:TGME49_239620 ^@ http://purl.uniprot.org/uniprot/S8F7Q2 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/508771:TGME49_287200 ^@ http://purl.uniprot.org/uniprot/A0A125YTQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM234 family.|||Membrane http://togogenome.org/gene/508771:TGME49_268280 ^@ http://purl.uniprot.org/uniprot/S8GIF1 ^@ Similarity ^@ Belongs to the peptidase C15 family. http://togogenome.org/gene/508771:TGME49_247700 ^@ http://purl.uniprot.org/uniprot/A0A125YU40 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_312430 ^@ http://purl.uniprot.org/uniprot/S8EUG5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_216500 ^@ http://purl.uniprot.org/uniprot/S8G1V5 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_310118 ^@ http://purl.uniprot.org/uniprot/S8GCU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS29 family.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_254080 ^@ http://purl.uniprot.org/uniprot/S8FDI8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_313980 ^@ http://purl.uniprot.org/uniprot/A0A125YNS7 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family. http://togogenome.org/gene/508771:TGME49_285940 ^@ http://purl.uniprot.org/uniprot/S8FBM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HAP2/GCS1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/508771:TGME49_209140 ^@ http://purl.uniprot.org/uniprot/S8GKJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ASF1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_203280 ^@ http://purl.uniprot.org/uniprot/A0A125YQY2 ^@ Similarity ^@ Belongs to the FAM133 family. http://togogenome.org/gene/508771:TGME49_272270 ^@ http://purl.uniprot.org/uniprot/S8F4Y2 ^@ Similarity ^@ Belongs to the TYW1 family. http://togogenome.org/gene/508771:TGME49_242070 ^@ http://purl.uniprot.org/uniprot/A0A125YLM6 ^@ Similarity ^@ Belongs to the cAMP-dependent kinase regulatory chain family. http://togogenome.org/gene/508771:TGME49_249390 ^@ http://purl.uniprot.org/uniprot/S8EVN8 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/508771:TGME49_218520 ^@ http://purl.uniprot.org/uniprot/S8EUN7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_202910 ^@ http://purl.uniprot.org/uniprot/S8F316 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/508771:TGME49_227560 ^@ http://purl.uniprot.org/uniprot/S8G6A2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_301450 ^@ http://purl.uniprot.org/uniprot/S8GRX6 ^@ Similarity ^@ Belongs to the TIP family. http://togogenome.org/gene/508771:TGME49_283780 ^@ http://purl.uniprot.org/uniprot/S8FBB6 ^@ Similarity ^@ Belongs to the GPI family. http://togogenome.org/gene/508771:TGME49_235950 ^@ http://purl.uniprot.org/uniprot/S8EZP3 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/508771:TGME49_214970 ^@ http://purl.uniprot.org/uniprot/S8ESW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/508771:TGME49_268850 ^@ http://purl.uniprot.org/uniprot/A0A125YLV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_216480 ^@ http://purl.uniprot.org/uniprot/S8EWU8 ^@ Similarity ^@ Belongs to the NMD3 family. http://togogenome.org/gene/508771:TGME49_272710 ^@ http://purl.uniprot.org/uniprot/S8F1W8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_245680 ^@ http://purl.uniprot.org/uniprot/A0A125YMU0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/508771:TGME49_319658 ^@ http://purl.uniprot.org/uniprot/A0A125YPA7 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/508771:TGME49_234360 ^@ http://purl.uniprot.org/uniprot/S8F040 ^@ Function|||Similarity ^@ Belongs to the type IB topoisomerase family.|||Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/508771:TGME49_285800 ^@ http://purl.uniprot.org/uniprot/S8F8J9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_315250 ^@ http://purl.uniprot.org/uniprot/S8EQR9 ^@ Similarity ^@ Belongs to the MYG1 family. http://togogenome.org/gene/508771:TGME49_279100 ^@ http://purl.uniprot.org/uniprot/S8GJB7 ^@ Developmental Stage|||Function|||Polymorphism|||Subcellular Location Annotation|||Subunit ^@ During host cell infection by tachyzoites, does not play a role in tethering the parasitophorous vacuole to the host mitochondria, probably because it does not bind host mitochondrial import protein TOMM70.|||Expressed in tachyzoites (at protein level).|||Interacts with host SAMM50.|||Parasitophorous vacuole membrane|||The MAF1 locus encodes multiple tandemly duplicated paralogs that vary in expression, sequence and copy number across T.gondii strains (PubMed:26920761). For instance, type I strain GT1 has 6 copies, type I strain RH has 4 copies, type II strains ME49 and PRU have 4 copies, type III strain VEG has 4 copies and type III strain CTG has only 2 copies (PubMed:26920761). The paralogs are classified into two groups, a and b and have probably arisen from the neofunctionalization of an ancestral MAF1 a gene (PubMed:26920761). They are characterized by the presence or absence of a repetitive stretch of 4 to 7 prolines followed by a serine (P(4:7)S), as well as differences in the amino acids surrounding the proline motif (PubMed:26920761). This motif is either completely missing (a and b0 paralogs) or repeated up to six times (b paralogs) (PubMed:26920761). Across the strains, transcript levels for the a paralogs are similar, however, in type II strain ME49, transcript levels for the b paralogs are low and no paralog MAF1 b1 protein is produced (PubMed:26920761). Paralogs differ in their ability to mediate host mitochondrial association (HMA), but also in their ability to confer a selective advantage during infection in a mouse model (PubMed:26920761). Tachyzoites from type I and III strains associate with host mitochondria (HMA(+)), while tachyzoites from type II strains, such as ME49, do not associate with host mitochondria (HMA(-)) due to a lack of MAF1 b1 expression (PubMed:26920761). http://togogenome.org/gene/508771:TGME49_266270 ^@ http://purl.uniprot.org/uniprot/S8EZ57 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/508771:TGME49_288530 ^@ http://purl.uniprot.org/uniprot/S8EZR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||nucleolus http://togogenome.org/gene/508771:TGME49_318590 ^@ http://purl.uniprot.org/uniprot/A0A125YN15 ^@ Similarity ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family. http://togogenome.org/gene/508771:TGME49_240500 ^@ http://purl.uniprot.org/uniprot/S8F4H3 ^@ Similarity ^@ Belongs to the PITHD1 family. http://togogenome.org/gene/508771:TGME49_264485 ^@ http://purl.uniprot.org/uniprot/S8GH92 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_225710 ^@ http://purl.uniprot.org/uniprot/A0A125YKI7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Tim17/Tim22/Tim23 family.|||Component of the TIM22 complex.|||Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_251740 ^@ http://purl.uniprot.org/uniprot/A0A125YNT3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_315560 ^@ http://purl.uniprot.org/uniprot/S8EXA2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_230520 ^@ http://purl.uniprot.org/uniprot/A0A125YLU4 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/508771:TGME49_215940 ^@ http://purl.uniprot.org/uniprot/A0A125YUW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_321400 ^@ http://purl.uniprot.org/uniprot/S8FBK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_236200 ^@ http://purl.uniprot.org/uniprot/S8EWC0 ^@ Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family. http://togogenome.org/gene/508771:TGME49_313050 ^@ http://purl.uniprot.org/uniprot/A0A125YV83 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/508771:TGME49_251510 ^@ http://purl.uniprot.org/uniprot/S8EPB5 ^@ Similarity ^@ Belongs to the peptidase C48 family. http://togogenome.org/gene/508771:TGME49_318510 ^@ http://purl.uniprot.org/uniprot/A0A125YPA6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. http://togogenome.org/gene/508771:TGME49_270780 ^@ http://purl.uniprot.org/uniprot/A0A125YFP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/508771:TGME49_264030 ^@ http://purl.uniprot.org/uniprot/S8F550 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/508771:TGME49_248840 ^@ http://purl.uniprot.org/uniprot/A0A125YV81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/508771:TGME49_273720 ^@ http://purl.uniprot.org/uniprot/S8GJL2 ^@ Similarity ^@ Belongs to the FAM221 family. http://togogenome.org/gene/508771:TGME49_217460 ^@ http://purl.uniprot.org/uniprot/A0A125YXL3 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/508771:TGME49_216040 ^@ http://purl.uniprot.org/uniprot/A0A125YGX6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/508771:TGME49_260680 ^@ http://purl.uniprot.org/uniprot/S8F1F4 ^@ Similarity ^@ Belongs to the eukaryotic-type primase small subunit family. http://togogenome.org/gene/508771:TGME49_290940 ^@ http://purl.uniprot.org/uniprot/S8GHX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.|||Membrane http://togogenome.org/gene/508771:TGME49_249980 ^@ http://purl.uniprot.org/uniprot/S8GA16 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_222860 ^@ http://purl.uniprot.org/uniprot/A0A125YS99 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit B family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. http://togogenome.org/gene/508771:TGME49_221830 ^@ http://purl.uniprot.org/uniprot/S8GTW7 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/508771:TGME49_229470 ^@ http://purl.uniprot.org/uniprot/A0A125YWR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CASC3 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/508771:TGME49_219280 ^@ http://purl.uniprot.org/uniprot/A0A125YSC1 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/508771:TGME49_313240 ^@ http://purl.uniprot.org/uniprot/S8EUA0 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/508771:TGME49_262930 ^@ http://purl.uniprot.org/uniprot/A0A125YQ49 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DPM3 family.|||Component of the dolichol-phosphate mannose (DPM) synthase complex.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. http://togogenome.org/gene/508771:TGME49_264190 ^@ http://purl.uniprot.org/uniprot/S8F293 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruD family. http://togogenome.org/gene/508771:TGME49_257060 ^@ http://purl.uniprot.org/uniprot/A0A125YVW9 ^@ Similarity ^@ Belongs to the DENR family. http://togogenome.org/gene/508771:TGME49_215280 ^@ http://purl.uniprot.org/uniprot/A0A125YH79 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/508771:TGME49_260320 ^@ http://purl.uniprot.org/uniprot/S8F1C8 ^@ Similarity ^@ Belongs to the NOC2 family. http://togogenome.org/gene/508771:TGME49_240650 ^@ http://purl.uniprot.org/uniprot/A0A125YGM1 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/508771:TGME49_255370 ^@ http://purl.uniprot.org/uniprot/S8GBF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tic20 family.|||Membrane http://togogenome.org/gene/508771:TGME49_250810 ^@ http://purl.uniprot.org/uniprot/A0A125YPP3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/508771:TGME49_210800 ^@ http://purl.uniprot.org/uniprot/A0A125YRE9 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/508771:TGME49_272720 ^@ http://purl.uniprot.org/uniprot/S8F527 ^@ Similarity ^@ In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family. http://togogenome.org/gene/508771:TGME49_316430 ^@ http://purl.uniprot.org/uniprot/S8EQG6 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. http://togogenome.org/gene/508771:TGME49_266130 ^@ http://purl.uniprot.org/uniprot/A0A125YL97 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/508771:TGME49_293350 ^@ http://purl.uniprot.org/uniprot/A0A125YWM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_319560 ^@ http://purl.uniprot.org/uniprot/A0A125YUG9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_259550 ^@ http://purl.uniprot.org/uniprot/A0A125YMN5 ^@ Similarity ^@ In the C-terminal section; belongs to the DHPS family. http://togogenome.org/gene/508771:TGME49_247370 ^@ http://purl.uniprot.org/uniprot/S8ENM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_243760 ^@ http://purl.uniprot.org/uniprot/S8GPK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_222410 ^@ http://purl.uniprot.org/uniprot/A0A125YYE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lipase maturation factor family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_259580 ^@ http://purl.uniprot.org/uniprot/A0A125YNT5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_242360 ^@ http://purl.uniprot.org/uniprot/S8F3P9 ^@ Similarity ^@ Belongs to the TTC21 family. http://togogenome.org/gene/508771:TGME49_270070 ^@ http://purl.uniprot.org/uniprot/S8F4J7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_217020 ^@ http://purl.uniprot.org/uniprot/A0A125YK82 ^@ Similarity ^@ Belongs to the AFG1 ATPase family. http://togogenome.org/gene/508771:TGME49_248200 ^@ http://purl.uniprot.org/uniprot/A0A125YXC0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/508771:TGME49_259240 ^@ http://purl.uniprot.org/uniprot/A0A125YS46 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS21 family. http://togogenome.org/gene/508771:TGME49_295410 ^@ http://purl.uniprot.org/uniprot/S8GV22 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_268020 ^@ http://purl.uniprot.org/uniprot/S8F417 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/508771:TGME49_202300 ^@ http://purl.uniprot.org/uniprot/A0A125YMV5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).|||Cytoplasm|||Homodimer.|||Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. http://togogenome.org/gene/508771:TGME49_314530 ^@ http://purl.uniprot.org/uniprot/S8GBW1 ^@ Similarity ^@ Belongs to the RPAP1 family. http://togogenome.org/gene/508771:TGME49_237700 ^@ http://purl.uniprot.org/uniprot/S8GPW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Membrane|||Monomer. http://togogenome.org/gene/508771:TGME49_244040 ^@ http://purl.uniprot.org/uniprot/S8GPL9 ^@ Similarity ^@ Belongs to the VAC14 family. http://togogenome.org/gene/508771:TGME49_242300 ^@ http://purl.uniprot.org/uniprot/A0A125YJ98 ^@ Function|||Similarity ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). http://togogenome.org/gene/508771:TGME49_251480 ^@ http://purl.uniprot.org/uniprot/S8EW15 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/508771:TGME49_319930 ^@ http://purl.uniprot.org/uniprot/S8GI39 ^@ Similarity ^@ Belongs to the SAPS family. http://togogenome.org/gene/508771:TGME49_267440 ^@ http://purl.uniprot.org/uniprot/A0A125YZS7 ^@ Similarity ^@ Belongs to the RING-type zinc finger family. LOG2 subfamily. http://togogenome.org/gene/508771:TGME49_293830 ^@ http://purl.uniprot.org/uniprot/A0A125YLP0 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/508771:TGME49_226870 ^@ http://purl.uniprot.org/uniprot/S8F111 ^@ Function|||Similarity ^@ Belongs to the tubulin family.|||Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. http://togogenome.org/gene/508771:TGME49_239590 ^@ http://purl.uniprot.org/uniprot/A0A125YMP2 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/508771:TGME49_309730 ^@ http://purl.uniprot.org/uniprot/A0A125YKW4 ^@ Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/508771:TGME49_263030 ^@ http://purl.uniprot.org/uniprot/A0A125YGY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/508771:TGME49_278800 ^@ http://purl.uniprot.org/uniprot/S8G183 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_299020 ^@ http://purl.uniprot.org/uniprot/S8FD55 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_308040 ^@ http://purl.uniprot.org/uniprot/S8FZA9 ^@ Similarity ^@ Belongs to the ZPR1 family. http://togogenome.org/gene/508771:TGME49_233000 ^@ http://purl.uniprot.org/uniprot/S8GAM4 ^@ Similarity ^@ Belongs to the SPT5 family. http://togogenome.org/gene/508771:TGME49_237280 ^@ http://purl.uniprot.org/uniprot/S8G4L8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_246800 ^@ http://purl.uniprot.org/uniprot/A0A125YU32 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S9C family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/508771:TGME49_235905 ^@ http://purl.uniprot.org/uniprot/S8EWE3 ^@ Similarity ^@ Belongs to the RNase Z family. http://togogenome.org/gene/508771:TGME49_258680 ^@ http://purl.uniprot.org/uniprot/S8F3Z8 ^@ Similarity ^@ Belongs to the TBP family. http://togogenome.org/gene/508771:TGME49_311400 ^@ http://purl.uniprot.org/uniprot/S8GCI0 ^@ Similarity ^@ Belongs to the WD repeat SEC31 family. http://togogenome.org/gene/508771:TGME49_243280 ^@ http://purl.uniprot.org/uniprot/S8FA10 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRM5 / TYW2 family.|||Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mitochondrion matrix|||Monomer.|||Nucleus|||Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. http://togogenome.org/gene/508771:TGME49_251630 ^@ http://purl.uniprot.org/uniprot/S8EW32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_277150 ^@ http://purl.uniprot.org/uniprot/S8ET06 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.|||Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Nucleus http://togogenome.org/gene/508771:TGME49_288820 ^@ http://purl.uniprot.org/uniprot/S8G829 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_311110 ^@ http://purl.uniprot.org/uniprot/A0A125YFZ2 ^@ Similarity ^@ Belongs to the UFM1 family. http://togogenome.org/gene/508771:TGME49_260630 ^@ http://purl.uniprot.org/uniprot/S8F1F1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_203010 ^@ http://purl.uniprot.org/uniprot/S8F307 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/508771:TGME49_316110 ^@ http://purl.uniprot.org/uniprot/S8EX65 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/508771:TGME49_231380 ^@ http://purl.uniprot.org/uniprot/A0A125YT13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/508771:TGME49_232830 ^@ http://purl.uniprot.org/uniprot/A0A125YQ93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.|||Membrane http://togogenome.org/gene/508771:TGME49_215385 ^@ http://purl.uniprot.org/uniprot/S8G497 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_309580 ^@ http://purl.uniprot.org/uniprot/S8ES78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_239250 ^@ http://purl.uniprot.org/uniprot/A0A125YVD7 ^@ Similarity ^@ Belongs to the eukaryotic diacylglycerol kinase family. http://togogenome.org/gene/508771:TGME49_216275 ^@ http://purl.uniprot.org/uniprot/A0A125YL61 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/508771:TGME49_201830 ^@ http://purl.uniprot.org/uniprot/S8F6A8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL54 family.|||Mitochondrion http://togogenome.org/gene/508771:TGME49_242460 ^@ http://purl.uniprot.org/uniprot/A0A125YHX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_223810 ^@ http://purl.uniprot.org/uniprot/S8EX21 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_304770 ^@ http://purl.uniprot.org/uniprot/A0A125YYP2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/508771:TGME49_288860 ^@ http://purl.uniprot.org/uniprot/A0A125YQV8 ^@ Similarity ^@ Belongs to the RuvB family. http://togogenome.org/gene/508771:TGME49_218960 ^@ http://purl.uniprot.org/uniprot/S8EQW3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_307580 ^@ http://purl.uniprot.org/uniprot/S8F1Z4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_248250 ^@ http://purl.uniprot.org/uniprot/A0A125YKX5 ^@ Similarity ^@ Belongs to the PHF5 family. http://togogenome.org/gene/508771:TGME49_243350 ^@ http://purl.uniprot.org/uniprot/S8GF54 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C26 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular space http://togogenome.org/gene/508771:TGME49_258940 ^@ http://purl.uniprot.org/uniprot/A0A125YRH9 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/508771:TGME49_236070 ^@ http://purl.uniprot.org/uniprot/S8ETF2 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/508771:TGME49_261530 ^@ http://purl.uniprot.org/uniprot/S8F7Q0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_273760 ^@ http://purl.uniprot.org/uniprot/A0A125YXI9 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/508771:TGME49_258050 ^@ http://purl.uniprot.org/uniprot/A0A125YYA2 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/508771:TGME49_206350 ^@ http://purl.uniprot.org/uniprot/A0A125YR12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_232120 ^@ http://purl.uniprot.org/uniprot/S8GK54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSC1 (TC 1.A.17) family.|||Membrane http://togogenome.org/gene/508771:TGME49_214270 ^@ http://purl.uniprot.org/uniprot/S8GDQ5 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. http://togogenome.org/gene/508771:TGME49_212290 ^@ http://purl.uniprot.org/uniprot/S8F069 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS19 family. http://togogenome.org/gene/508771:TGME49_212960 ^@ http://purl.uniprot.org/uniprot/S8GRH6 ^@ Similarity ^@ Belongs to the fl(2)d family. http://togogenome.org/gene/508771:TGME49_315810 ^@ http://purl.uniprot.org/uniprot/S8ETM8 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/508771:TGME49_319950 ^@ http://purl.uniprot.org/uniprot/A0A125YJB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP23/FCF1 family. FCF1 subfamily.|||nucleolus http://togogenome.org/gene/508771:TGME49_257050 ^@ http://purl.uniprot.org/uniprot/S8F0N1 ^@ Similarity ^@ Belongs to the PanB family.|||Belongs to the ketopantoate reductase family. http://togogenome.org/gene/508771:TGME49_263860 ^@ http://purl.uniprot.org/uniprot/S8GDB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TLS1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_246020 ^@ http://purl.uniprot.org/uniprot/A0A125YZI6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_290930 ^@ http://purl.uniprot.org/uniprot/S8F3J1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MND1 family.|||Nucleus|||Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. http://togogenome.org/gene/508771:TGME49_223020 ^@ http://purl.uniprot.org/uniprot/S8GU38 ^@ Similarity|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Homodimer. http://togogenome.org/gene/508771:TGME49_225290 ^@ http://purl.uniprot.org/uniprot/S8G5S0 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/508771:TGME49_208200 ^@ http://purl.uniprot.org/uniprot/A0A125YX64 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/508771:TGME49_263190 ^@ http://purl.uniprot.org/uniprot/S8F847 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/508771:TGME49_252850 ^@ http://purl.uniprot.org/uniprot/S8GTG8 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/508771:TGME49_318140 ^@ http://purl.uniprot.org/uniprot/A0A125YQG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNU66/SART1 family.|||Nucleus http://togogenome.org/gene/508771:TGME49_306960 ^@ http://purl.uniprot.org/uniprot/S8EZ50 ^@ Similarity ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily. http://togogenome.org/gene/508771:TGME49_300340 ^@ http://purl.uniprot.org/uniprot/S8GAU2 ^@ Similarity ^@ Belongs to the CAF1 family. http://togogenome.org/gene/508771:TGME49_289930 ^@ http://purl.uniprot.org/uniprot/S8GHQ6 ^@ Similarity ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. http://togogenome.org/gene/508771:TGME49_252640 ^@ http://purl.uniprot.org/uniprot/S8FAQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.|||Cell membrane http://togogenome.org/gene/508771:TGME49_282230 ^@ http://purl.uniprot.org/uniprot/A0A125YFY5 ^@ Similarity ^@ In the C-terminal section; belongs to the sulfate adenylyltransferase family.|||In the N-terminal section; belongs to the APS kinase family. http://togogenome.org/gene/508771:TGME49_263040 ^@ http://purl.uniprot.org/uniprot/A0A125YT03 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/508771:TGME49_274020 ^@ http://purl.uniprot.org/uniprot/S8GJP6 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_313580 ^@ http://purl.uniprot.org/uniprot/S8EU59 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/508771:TGME49_211710 ^@ http://purl.uniprot.org/uniprot/A0A125YSH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/508771:TGME49_222020 ^@ http://purl.uniprot.org/uniprot/S8FB50 ^@ Similarity|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Monomer. http://togogenome.org/gene/508771:TGME49_224190 ^@ http://purl.uniprot.org/uniprot/S8EX48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/508771:TGME49_217700 ^@ http://purl.uniprot.org/uniprot/S8EN98 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/508771:TGME49_210280 ^@ http://purl.uniprot.org/uniprot/A0A125YY40 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/508771:TGME49_226710 ^@ http://purl.uniprot.org/uniprot/S8F0Z6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/508771:TGME49_299190 ^@ http://purl.uniprot.org/uniprot/A0A125YX97 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/508771:TGME49_226970 ^@ http://purl.uniprot.org/uniprot/A0A125YQR6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/508771:TGME49_217182 ^@ http://purl.uniprot.org/uniprot/S8GBB7 ^@ Similarity ^@ Belongs to the RdRP family. http://togogenome.org/gene/508771:TGME49_205430 ^@ http://purl.uniprot.org/uniprot/A0A125YMQ3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/508771:TGME49_230070 ^@ http://purl.uniprot.org/uniprot/A0A125YWC2 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/508771:TGME49_310760 ^@ http://purl.uniprot.org/uniprot/S8GCN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Enzyme with a broad specificity.|||Membrane http://togogenome.org/gene/508771:TGME49_224850 ^@ http://purl.uniprot.org/uniprot/S8GEW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyadenylate-binding protein type-1 family.|||Binds the poly(A) tail of mRNA.|||Cytoplasm http://togogenome.org/gene/508771:TGME49_218210 ^@ http://purl.uniprot.org/uniprot/A0A125YGL5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/508771:TGME49_232640 ^@ http://purl.uniprot.org/uniprot/A0A125YXQ3 ^@ Function|||Similarity ^@ Belongs to the KptA/TPT1 family.|||Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate. http://togogenome.org/gene/508771:TGME49_237240 ^@ http://purl.uniprot.org/uniprot/S8GDU7 ^@ Similarity ^@ Belongs to the TSR2 family. http://togogenome.org/gene/508771:TGME49_226270 ^@ http://purl.uniprot.org/uniprot/S8EXK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM147 family.|||Cell membrane|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/508771:TGME49_273390 ^@ http://purl.uniprot.org/uniprot/A0A125YLA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/508771:TGME49_318150 ^@ http://purl.uniprot.org/uniprot/S8GS64 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/508771:TGME49_290290 ^@ http://purl.uniprot.org/uniprot/S8G8F6 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. http://togogenome.org/gene/508771:TGME49_202285 ^@ http://purl.uniprot.org/uniprot/S8GNV4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/508771:TGME49_242580 ^@ http://purl.uniprot.org/uniprot/S8F3Q7 ^@ Similarity ^@ Belongs to the NARF family. http://togogenome.org/gene/508771:TGME49_230570 ^@ http://purl.uniprot.org/uniprot/S8F2Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/508771:TGME49_304680 ^@ http://purl.uniprot.org/uniprot/A0A125YIN9 ^@ Similarity ^@ Belongs to the DDI1 family. http://togogenome.org/gene/508771:TGME49_236920 ^@ http://purl.uniprot.org/uniprot/A0A125YZE2 ^@ Similarity ^@ Belongs to the DSS1/SEM1 family. http://togogenome.org/gene/508771:TGME49_236530 ^@ http://purl.uniprot.org/uniprot/A0A125YQD2 ^@ Function ^@ Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.