http://togogenome.org/gene/515620:EUBELI_RS12650 ^@ http://purl.uniprot.org/uniprot/C4Z6P9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/515620:EUBELI_RS08400 ^@ http://purl.uniprot.org/uniprot/C4Z3E8 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/515620:EUBELI_RS12750 ^@ http://purl.uniprot.org/uniprot/C4Z6S0 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family. LacC subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/515620:EUBELI_RS01695 ^@ http://purl.uniprot.org/uniprot/C4Z2Y0 ^@ Similarity ^@ Belongs to the CbxX/CfxQ family. http://togogenome.org/gene/515620:EUBELI_RS01105 ^@ http://purl.uniprot.org/uniprot/C4Z276 ^@ Similarity ^@ Belongs to the FlgM family. http://togogenome.org/gene/515620:EUBELI_RS09705 ^@ http://purl.uniprot.org/uniprot/C4Z4W0 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/515620:EUBELI_RS09400 ^@ http://purl.uniprot.org/uniprot/C4Z4Q6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/515620:EUBELI_RS01605 ^@ http://purl.uniprot.org/uniprot/C4Z2W2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS03230 ^@ http://purl.uniprot.org/uniprot/C4Z4Y4 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/515620:EUBELI_RS01120 ^@ http://purl.uniprot.org/uniprot/C4Z279 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/515620:EUBELI_RS05105 ^@ http://purl.uniprot.org/uniprot/C4Z0E5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/515620:EUBELI_RS12000 ^@ http://purl.uniprot.org/uniprot/C4Z6B4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS01115 ^@ http://purl.uniprot.org/uniprot/C4Z278 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/515620:EUBELI_RS03305 ^@ http://purl.uniprot.org/uniprot/C4Z4Z9 ^@ Similarity ^@ Belongs to the ATP:guanido phosphotransferase family. http://togogenome.org/gene/515620:EUBELI_RS06435 ^@ http://purl.uniprot.org/uniprot/C4Z159 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/515620:EUBELI_RS09210 ^@ http://purl.uniprot.org/uniprot/C4Z4L6 ^@ Function|||Similarity ^@ Belongs to the SpoVG family.|||Could be involved in septation. http://togogenome.org/gene/515620:EUBELI_RS08720 ^@ http://purl.uniprot.org/uniprot/C4Z3X9 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/515620:EUBELI_RS12065 ^@ http://purl.uniprot.org/uniprot/C4Z6C6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.|||Catalyzes the sodium-dependent transport of glutamate.|||Cell membrane http://togogenome.org/gene/515620:EUBELI_RS09335 ^@ http://purl.uniprot.org/uniprot/C4Z4P1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/515620:EUBELI_RS11185 ^@ http://purl.uniprot.org/uniprot/C4Z7P5 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/515620:EUBELI_RS05050 ^@ http://purl.uniprot.org/uniprot/C4Z0D4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/515620:EUBELI_RS00055 ^@ http://purl.uniprot.org/uniprot/C4Z182 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/515620:EUBELI_RS01365 ^@ http://purl.uniprot.org/uniprot/C4Z2R5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/515620:EUBELI_RS01680 ^@ http://purl.uniprot.org/uniprot/C4Z2X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS05905 ^@ http://purl.uniprot.org/uniprot/C4Z0V6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/515620:EUBELI_RS07775 ^@ http://purl.uniprot.org/uniprot/C4Z318 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/515620:EUBELI_RS06885 ^@ http://purl.uniprot.org/uniprot/C4Z1Q4 ^@ Similarity ^@ Belongs to the agmatine deiminase family. http://togogenome.org/gene/515620:EUBELI_RS02330 ^@ http://purl.uniprot.org/uniprot/C4Z3M8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS09595 ^@ http://purl.uniprot.org/uniprot/C4Z4T8 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/515620:EUBELI_RS10905 ^@ http://purl.uniprot.org/uniprot/C4Z7I3 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/515620:EUBELI_RS00260 ^@ http://purl.uniprot.org/uniprot/C4Z1B4 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/515620:EUBELI_RS06205 ^@ http://purl.uniprot.org/uniprot/C4Z113 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/515620:EUBELI_RS08140 ^@ http://purl.uniprot.org/uniprot/C4Z393 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS12785 ^@ http://purl.uniprot.org/uniprot/C4Z6S7 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/515620:EUBELI_RS13205 ^@ http://purl.uniprot.org/uniprot/C4Z719 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/515620:EUBELI_RS11225 ^@ http://purl.uniprot.org/uniprot/C4Z7Q3 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/515620:EUBELI_RS06465 ^@ http://purl.uniprot.org/uniprot/C4Z165 ^@ Similarity ^@ Belongs to the cycloisomerase 2 family. http://togogenome.org/gene/515620:EUBELI_RS05750 ^@ http://purl.uniprot.org/uniprot/C4Z0S3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/515620:EUBELI_RS03380 ^@ http://purl.uniprot.org/uniprot/C4Z510 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/515620:EUBELI_RS02850 ^@ http://purl.uniprot.org/uniprot/C4Z4C1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/515620:EUBELI_RS07695 ^@ http://purl.uniprot.org/uniprot/C4Z2L6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell membrane|||Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS01775 ^@ http://purl.uniprot.org/uniprot/C4Z2Z6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/515620:EUBELI_RS04810 ^@ http://purl.uniprot.org/uniprot/C4Z085 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/515620:EUBELI_RS05470 ^@ http://purl.uniprot.org/uniprot/C4Z0L6 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/515620:EUBELI_RS04640 ^@ http://purl.uniprot.org/uniprot/C4Z050 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS06165 ^@ http://purl.uniprot.org/uniprot/C4Z105 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/515620:EUBELI_RS07975 ^@ http://purl.uniprot.org/uniprot/C4Z360 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS04295 ^@ http://purl.uniprot.org/uniprot/C4Z5N7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/515620:EUBELI_RS06230 ^@ http://purl.uniprot.org/uniprot/C4Z119 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS01470 ^@ http://purl.uniprot.org/uniprot/C4Z2T6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/515620:EUBELI_RS05965 ^@ http://purl.uniprot.org/uniprot/C4Z0W7 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/515620:EUBELI_RS03855 ^@ http://purl.uniprot.org/uniprot/C4Z5F3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CodY family.|||Cytoplasm|||DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion. http://togogenome.org/gene/515620:EUBELI_RS04160 ^@ http://purl.uniprot.org/uniprot/C4Z5L1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS14790 ^@ http://purl.uniprot.org/uniprot/C4Z3H0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/515620:EUBELI_RS01480 ^@ http://purl.uniprot.org/uniprot/C4Z2T8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/515620:EUBELI_RS02510 ^@ http://purl.uniprot.org/uniprot/C4Z3R4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/515620:EUBELI_RS04105 ^@ http://purl.uniprot.org/uniprot/C4Z5K3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/515620:EUBELI_RS09920 ^@ http://purl.uniprot.org/uniprot/C4Z5D7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/515620:EUBELI_RS02115 ^@ http://purl.uniprot.org/uniprot/C4Z3I4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS13675 ^@ http://purl.uniprot.org/uniprot/C4Z2L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS05565 ^@ http://purl.uniprot.org/uniprot/C4Z0N6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/515620:EUBELI_RS09495 ^@ http://purl.uniprot.org/uniprot/C4Z4R8 ^@ Similarity ^@ Belongs to the aconitase/IPM isomerase family. http://togogenome.org/gene/515620:EUBELI_RS11130 ^@ http://purl.uniprot.org/uniprot/C4Z7N4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS04635 ^@ http://purl.uniprot.org/uniprot/C4Z049 ^@ Function|||Subcellular Location Annotation ^@ ATPase. Has a role at an early stage in the morphogenesis of the spore coat.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS05600 ^@ http://purl.uniprot.org/uniprot/C4Z0P3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS14665 ^@ http://purl.uniprot.org/uniprot/C4Z3C6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS06135 ^@ http://purl.uniprot.org/uniprot/C4Z0Z9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS00750 ^@ http://purl.uniprot.org/uniprot/C4Z1Z7 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS05500 ^@ http://purl.uniprot.org/uniprot/C4Z0M2 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/515620:EUBELI_RS00875 ^@ http://purl.uniprot.org/uniprot/C4Z223 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS00300 ^@ http://purl.uniprot.org/uniprot/C4Z1C2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS03420 ^@ http://purl.uniprot.org/uniprot/C4Z518 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/515620:EUBELI_RS12735 ^@ http://purl.uniprot.org/uniprot/C4Z6R7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/515620:EUBELI_RS04275 ^@ http://purl.uniprot.org/uniprot/C4Z5N3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/515620:EUBELI_RS06455 ^@ http://purl.uniprot.org/uniprot/C4Z163 ^@ Similarity ^@ Belongs to the sigma-70 factor family. http://togogenome.org/gene/515620:EUBELI_RS09605 ^@ http://purl.uniprot.org/uniprot/C4Z4U0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS05840 ^@ http://purl.uniprot.org/uniprot/C4Z0U3 ^@ Function|||PTM|||Similarity|||Subunit ^@ Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.|||Belongs to the peptidase A25 family.|||Homotetramer.|||Initiates the rapid degradation of small, acid-soluble proteins during spore germination. http://togogenome.org/gene/515620:EUBELI_RS09815 ^@ http://purl.uniprot.org/uniprot/C4Z5B5 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/515620:EUBELI_RS02975 ^@ http://purl.uniprot.org/uniprot/C4Z4E7 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/515620:EUBELI_RS04780 ^@ http://purl.uniprot.org/uniprot/C4Z079 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/515620:EUBELI_RS01145 ^@ http://purl.uniprot.org/uniprot/C4Z284 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/515620:EUBELI_RS04770 ^@ http://purl.uniprot.org/uniprot/C4Z077 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/515620:EUBELI_RS05430 ^@ http://purl.uniprot.org/uniprot/C4Z0K8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS13235 ^@ http://purl.uniprot.org/uniprot/C4Z725 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS12885 ^@ http://purl.uniprot.org/uniprot/C4Z6V0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS01610 ^@ http://purl.uniprot.org/uniprot/C4Z2W3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/515620:EUBELI_RS07660 ^@ http://purl.uniprot.org/uniprot/C4Z2L0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/515620:EUBELI_RS09220 ^@ http://purl.uniprot.org/uniprot/C4Z4L8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/515620:EUBELI_RS09840 ^@ http://purl.uniprot.org/uniprot/C4Z5C0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS00895 ^@ http://purl.uniprot.org/uniprot/C4Z227 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/515620:EUBELI_RS07255 ^@ http://purl.uniprot.org/uniprot/C4Z2B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS06730 ^@ http://purl.uniprot.org/uniprot/C4Z1M4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/515620:EUBELI_RS04450 ^@ http://purl.uniprot.org/uniprot/C4Z5R5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS09620 ^@ http://purl.uniprot.org/uniprot/C4Z4U3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/515620:EUBELI_RS06635 ^@ http://purl.uniprot.org/uniprot/C4Z1K4 ^@ Similarity ^@ Belongs to the MecA family. http://togogenome.org/gene/515620:EUBELI_RS05475 ^@ http://purl.uniprot.org/uniprot/C4Z0L7 ^@ Function|||Similarity|||Subunit ^@ Associates with stalled 50S ribosomal subunits.|||Belongs to the NEMF family.|||Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. http://togogenome.org/gene/515620:EUBELI_RS06190 ^@ http://purl.uniprot.org/uniprot/C4Z110 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/515620:EUBELI_RS07540 ^@ http://purl.uniprot.org/uniprot/C4Z2I3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/515620:EUBELI_RS02370 ^@ http://purl.uniprot.org/uniprot/C4Z3N6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MrnC RNase family.|||Cytoplasm|||Homodimer.|||Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. http://togogenome.org/gene/515620:EUBELI_RS00820 ^@ http://purl.uniprot.org/uniprot/C4Z212 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/515620:EUBELI_RS10895 ^@ http://purl.uniprot.org/uniprot/C4Z7I1 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/515620:EUBELI_RS13410 ^@ http://purl.uniprot.org/uniprot/C4Z762 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS02665 ^@ http://purl.uniprot.org/uniprot/C4Z481 ^@ Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS07035 ^@ http://purl.uniprot.org/uniprot/C4Z1T5 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/515620:EUBELI_RS00925 ^@ http://purl.uniprot.org/uniprot/C4Z236 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS04840 ^@ http://purl.uniprot.org/uniprot/C4Z091 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS08545 ^@ http://purl.uniprot.org/uniprot/C4Z3U2 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/515620:EUBELI_RS00350 ^@ http://purl.uniprot.org/uniprot/C4Z1D2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS06100 ^@ http://purl.uniprot.org/uniprot/C4Z0Z2 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/515620:EUBELI_RS07365 ^@ http://purl.uniprot.org/uniprot/C4Z2E0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS02935 ^@ http://purl.uniprot.org/uniprot/C4Z4D8 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/515620:EUBELI_RS09820 ^@ http://purl.uniprot.org/uniprot/C4Z5B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/515620:EUBELI_RS05235 ^@ http://purl.uniprot.org/uniprot/C4Z0G9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. http://togogenome.org/gene/515620:EUBELI_RS08065 ^@ http://purl.uniprot.org/uniprot/C4Z378 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS09205 ^@ http://purl.uniprot.org/uniprot/C4Z4L5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/515620:EUBELI_RS08195 ^@ http://purl.uniprot.org/uniprot/C4Z3A5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/515620:EUBELI_RS11945 ^@ http://purl.uniprot.org/uniprot/C4Z6A3 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/515620:EUBELI_RS05380 ^@ http://purl.uniprot.org/uniprot/C4Z0J8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the KduI family.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. http://togogenome.org/gene/515620:EUBELI_RS00650 ^@ http://purl.uniprot.org/uniprot/C4Z1X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS01355 ^@ http://purl.uniprot.org/uniprot/C4Z2R3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/515620:EUBELI_RS02795 ^@ http://purl.uniprot.org/uniprot/C4Z4A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/515620:EUBELI_RS01385 ^@ http://purl.uniprot.org/uniprot/C4Z2R9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/515620:EUBELI_RS08870 ^@ http://purl.uniprot.org/uniprot/C4Z409 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS07040 ^@ http://purl.uniprot.org/uniprot/C4Z1T6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/515620:EUBELI_RS07570 ^@ http://purl.uniprot.org/uniprot/C4Z2J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS03935 ^@ http://purl.uniprot.org/uniprot/C4Z5G9 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/515620:EUBELI_RS04475 ^@ http://purl.uniprot.org/uniprot/C4Z5S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS04715 ^@ http://purl.uniprot.org/uniprot/C4Z066 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS08810 ^@ http://purl.uniprot.org/uniprot/C4Z3Z7 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/515620:EUBELI_RS10270 ^@ http://purl.uniprot.org/uniprot/C4Z5Z2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RecU family.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS02825 ^@ http://purl.uniprot.org/uniprot/C4Z4B3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS04280 ^@ http://purl.uniprot.org/uniprot/C4Z5N4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/515620:EUBELI_RS01675 ^@ http://purl.uniprot.org/uniprot/C4Z2X6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Cell membrane|||Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).|||Membrane http://togogenome.org/gene/515620:EUBELI_RS09825 ^@ http://purl.uniprot.org/uniprot/C4Z5B7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/515620:EUBELI_RS07585 ^@ http://purl.uniprot.org/uniprot/C4Z2J5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS07165 ^@ http://purl.uniprot.org/uniprot/C4Z296 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/515620:EUBELI_RS02140 ^@ http://purl.uniprot.org/uniprot/C4Z3I9 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/515620:EUBELI_RS12965 ^@ http://purl.uniprot.org/uniprot/C4Z6W7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/515620:EUBELI_RS05230 ^@ http://purl.uniprot.org/uniprot/C4Z0G8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/515620:EUBELI_RS00010 ^@ http://purl.uniprot.org/uniprot/C4Z173 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/515620:EUBELI_RS12085 ^@ http://purl.uniprot.org/uniprot/C4Z6D1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS03535 ^@ http://purl.uniprot.org/uniprot/C4Z541 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/515620:EUBELI_RS09915 ^@ http://purl.uniprot.org/uniprot/C4Z5D6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/515620:EUBELI_RS05085 ^@ http://purl.uniprot.org/uniprot/C4Z0E1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/515620:EUBELI_RS13610 ^@ http://purl.uniprot.org/uniprot/C4Z0Y4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Secreted http://togogenome.org/gene/515620:EUBELI_RS13050 ^@ http://purl.uniprot.org/uniprot/C4Z6Y7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS02180 ^@ http://purl.uniprot.org/uniprot/C4Z3J9 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/515620:EUBELI_RS03500 ^@ http://purl.uniprot.org/uniprot/C4Z534 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS07690 ^@ http://purl.uniprot.org/uniprot/C4Z2L5 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/515620:EUBELI_RS08500 ^@ http://purl.uniprot.org/uniprot/C4Z3T3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/515620:EUBELI_RS05465 ^@ http://purl.uniprot.org/uniprot/C4Z0L5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/515620:EUBELI_RS04880 ^@ http://purl.uniprot.org/uniprot/C4Z0A0 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/515620:EUBELI_RS05580 ^@ http://purl.uniprot.org/uniprot/C4Z0N9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/515620:EUBELI_RS03050 ^@ http://purl.uniprot.org/uniprot/C4Z4G2 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/515620:EUBELI_RS05030 ^@ http://purl.uniprot.org/uniprot/C4Z0D0 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/515620:EUBELI_RS08935 ^@ http://purl.uniprot.org/uniprot/C4Z422 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/515620:EUBELI_RS00585 ^@ http://purl.uniprot.org/uniprot/C4Z1W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS12755 ^@ http://purl.uniprot.org/uniprot/C4Z6S1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.|||Cell membrane|||Membrane|||Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. http://togogenome.org/gene/515620:EUBELI_RS08945 ^@ http://purl.uniprot.org/uniprot/C4Z424 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/515620:EUBELI_RS01345 ^@ http://purl.uniprot.org/uniprot/C4Z2R1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/515620:EUBELI_RS08825 ^@ http://purl.uniprot.org/uniprot/C4Z400 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/515620:EUBELI_RS05060 ^@ http://purl.uniprot.org/uniprot/C4Z0D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS01135 ^@ http://purl.uniprot.org/uniprot/C4Z282 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/515620:EUBELI_RS09200 ^@ http://purl.uniprot.org/uniprot/C4Z4L4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/515620:EUBELI_RS05225 ^@ http://purl.uniprot.org/uniprot/C4Z0G7 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/515620:EUBELI_RS06195 ^@ http://purl.uniprot.org/uniprot/C4Z111 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS11600 ^@ http://purl.uniprot.org/uniprot/C4Z626 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/515620:EUBELI_RS11190 ^@ http://purl.uniprot.org/uniprot/C4Z7P6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS04815 ^@ http://purl.uniprot.org/uniprot/C4Z086 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS04905 ^@ http://purl.uniprot.org/uniprot/C4Z0A5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/515620:EUBELI_RS02985 ^@ http://purl.uniprot.org/uniprot/C4Z4E9 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/515620:EUBELI_RS01580 ^@ http://purl.uniprot.org/uniprot/C4Z2V7 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/515620:EUBELI_RS05200 ^@ http://purl.uniprot.org/uniprot/C4Z0G2 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/515620:EUBELI_RS12325 ^@ http://purl.uniprot.org/uniprot/C4Z6H9 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS04530 ^@ http://purl.uniprot.org/uniprot/C4Z027 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/515620:EUBELI_RS11125 ^@ http://purl.uniprot.org/uniprot/C4Z7N3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS12400 ^@ http://purl.uniprot.org/uniprot/C4Z6J4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS01070 ^@ http://purl.uniprot.org/uniprot/C4Z268 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS05240 ^@ http://purl.uniprot.org/uniprot/C4Z0H0 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/515620:EUBELI_RS13110 ^@ http://purl.uniprot.org/uniprot/C4Z6Z9 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/515620:EUBELI_RS02750 ^@ http://purl.uniprot.org/uniprot/C4Z498 ^@ Similarity ^@ Belongs to the UPF0751 family. http://togogenome.org/gene/515620:EUBELI_RS12660 ^@ http://purl.uniprot.org/uniprot/C4Z6Q1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/515620:EUBELI_RS04935 ^@ http://purl.uniprot.org/uniprot/C4Z0B1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/515620:EUBELI_RS10950 ^@ http://purl.uniprot.org/uniprot/C4Z7J3 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/515620:EUBELI_RS06425 ^@ http://purl.uniprot.org/uniprot/C4Z157 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/515620:EUBELI_RS06650 ^@ http://purl.uniprot.org/uniprot/C4Z1K7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS03660 ^@ http://purl.uniprot.org/uniprot/C4Z568 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS06675 ^@ http://purl.uniprot.org/uniprot/C4Z1L3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family. http://togogenome.org/gene/515620:EUBELI_RS13785 ^@ http://purl.uniprot.org/uniprot/C4Z7X5 ^@ Similarity ^@ Belongs to the CbxX/CfxQ family. http://togogenome.org/gene/515620:EUBELI_RS03555 ^@ http://purl.uniprot.org/uniprot/C4Z545 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/515620:EUBELI_RS00725 ^@ http://purl.uniprot.org/uniprot/C4Z1Z2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/515620:EUBELI_RS00375 ^@ http://purl.uniprot.org/uniprot/C4Z1D7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS01995 ^@ http://purl.uniprot.org/uniprot/C4Z3F9 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/515620:EUBELI_RS06605 ^@ http://purl.uniprot.org/uniprot/C4Z1J8 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/515620:EUBELI_RS06775 ^@ http://purl.uniprot.org/uniprot/C4Z1N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS00370 ^@ http://purl.uniprot.org/uniprot/C4Z1D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS00395 ^@ http://purl.uniprot.org/uniprot/C4Z1E2 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/515620:EUBELI_RS05655 ^@ http://purl.uniprot.org/uniprot/C4Z0Q4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS03080 ^@ http://purl.uniprot.org/uniprot/C4Z4G9 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/515620:EUBELI_RS05075 ^@ http://purl.uniprot.org/uniprot/C4Z0D9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/515620:EUBELI_RS02355 ^@ http://purl.uniprot.org/uniprot/C4Z3N3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/515620:EUBELI_RS04965 ^@ http://purl.uniprot.org/uniprot/C4Z0B7 ^@ Cofactor|||Similarity ^@ Belongs to the UPF0313 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/515620:EUBELI_RS09045 ^@ http://purl.uniprot.org/uniprot/C4Z445 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS08105 ^@ http://purl.uniprot.org/uniprot/C4Z386 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/515620:EUBELI_RS00025 ^@ http://purl.uniprot.org/uniprot/C4Z176 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/515620:EUBELI_RS05020 ^@ http://purl.uniprot.org/uniprot/C4Z0C8 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/515620:EUBELI_RS05120 ^@ http://purl.uniprot.org/uniprot/C4Z0E8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS11890 ^@ http://purl.uniprot.org/uniprot/C4Z691 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/515620:EUBELI_RS12635 ^@ http://purl.uniprot.org/uniprot/C4Z6P6 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/515620:EUBELI_RS03650 ^@ http://purl.uniprot.org/uniprot/C4Z566 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS01735 ^@ http://purl.uniprot.org/uniprot/C4Z2Y8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/515620:EUBELI_RS07010 ^@ http://purl.uniprot.org/uniprot/C4Z1T0 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/515620:EUBELI_RS09040 ^@ http://purl.uniprot.org/uniprot/C4Z444 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/515620:EUBELI_RS01785 ^@ http://purl.uniprot.org/uniprot/C4Z2Z8 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/515620:EUBELI_RS05930 ^@ http://purl.uniprot.org/uniprot/C4Z0W1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS11005 ^@ http://purl.uniprot.org/uniprot/C4Z7K4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS03025 ^@ http://purl.uniprot.org/uniprot/C4Z4F7 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/515620:EUBELI_RS04100 ^@ http://purl.uniprot.org/uniprot/C4Z5K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS08905 ^@ http://purl.uniprot.org/uniprot/C4Z416 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS08495 ^@ http://purl.uniprot.org/uniprot/C4Z3T2 ^@ Function|||Similarity ^@ A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3'.|||Belongs to the DpnII type II restriction endonuclease family. http://togogenome.org/gene/515620:EUBELI_RS13200 ^@ http://purl.uniprot.org/uniprot/C4Z718 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/515620:EUBELI_RS03985 ^@ http://purl.uniprot.org/uniprot/C4Z5H9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/515620:EUBELI_RS07780 ^@ http://purl.uniprot.org/uniprot/C4Z319 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/515620:EUBELI_RS00755 ^@ http://purl.uniprot.org/uniprot/C4Z1Z8 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/515620:EUBELI_RS08990 ^@ http://purl.uniprot.org/uniprot/C4Z434 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/515620:EUBELI_RS03950 ^@ http://purl.uniprot.org/uniprot/C4Z5H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliN/MopA/SpaO family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS10570 ^@ http://purl.uniprot.org/uniprot/C4Z7B1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/515620:EUBELI_RS08175 ^@ http://purl.uniprot.org/uniprot/C4Z3A1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS08200 ^@ http://purl.uniprot.org/uniprot/C4Z3A6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS05890 ^@ http://purl.uniprot.org/uniprot/C4Z0V3 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/515620:EUBELI_RS01585 ^@ http://purl.uniprot.org/uniprot/C4Z2V8 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/515620:EUBELI_RS13365 ^@ http://purl.uniprot.org/uniprot/C4Z752 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/515620:EUBELI_RS01505 ^@ http://purl.uniprot.org/uniprot/C4Z2U3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/515620:EUBELI_RS04740 ^@ http://purl.uniprot.org/uniprot/C4Z071 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS04940 ^@ http://purl.uniprot.org/uniprot/C4Z0B2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.|||This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. http://togogenome.org/gene/515620:EUBELI_RS01075 ^@ http://purl.uniprot.org/uniprot/C4Z269 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/515620:EUBELI_RS07870 ^@ http://purl.uniprot.org/uniprot/C4Z337 ^@ Similarity ^@ Belongs to the peptidase C59 family. http://togogenome.org/gene/515620:EUBELI_RS06735 ^@ http://purl.uniprot.org/uniprot/C4Z1M5 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/515620:EUBELI_RS06580 ^@ http://purl.uniprot.org/uniprot/C4Z1J3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/515620:EUBELI_RS12835 ^@ http://purl.uniprot.org/uniprot/C4Z6T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS06315 ^@ http://purl.uniprot.org/uniprot/C4Z137 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/515620:EUBELI_RS05665 ^@ http://purl.uniprot.org/uniprot/C4Z0Q6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. http://togogenome.org/gene/515620:EUBELI_RS02080 ^@ http://purl.uniprot.org/uniprot/C4Z3H7 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/515620:EUBELI_RS07890 ^@ http://purl.uniprot.org/uniprot/C4Z341 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/515620:EUBELI_RS05165 ^@ http://purl.uniprot.org/uniprot/C4Z0F6 ^@ Similarity ^@ Belongs to the UPF0237 family. http://togogenome.org/gene/515620:EUBELI_RS05100 ^@ http://purl.uniprot.org/uniprot/C4Z0E4 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/515620:EUBELI_RS02690 ^@ http://purl.uniprot.org/uniprot/C4Z486 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/515620:EUBELI_RS04805 ^@ http://purl.uniprot.org/uniprot/C4Z084 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS09710 ^@ http://purl.uniprot.org/uniprot/C4Z4W1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/515620:EUBELI_RS06505 ^@ http://purl.uniprot.org/uniprot/C4Z1H6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/515620:EUBELI_RS12050 ^@ http://purl.uniprot.org/uniprot/C4Z6C3 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/515620:EUBELI_RS09650 ^@ http://purl.uniprot.org/uniprot/C4Z4U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CotF family.|||Spore coat http://togogenome.org/gene/515620:EUBELI_RS00530 ^@ http://purl.uniprot.org/uniprot/C4Z1G9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS06900 ^@ http://purl.uniprot.org/uniprot/C4Z1Q7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Cytoplasm|||Homodimer or homotetramer. http://togogenome.org/gene/515620:EUBELI_RS03460 ^@ http://purl.uniprot.org/uniprot/C4Z526 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/515620:EUBELI_RS06270 ^@ http://purl.uniprot.org/uniprot/C4Z128 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/515620:EUBELI_RS05635 ^@ http://purl.uniprot.org/uniprot/C4Z0Q0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/515620:EUBELI_RS04800 ^@ http://purl.uniprot.org/uniprot/C4Z083 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/515620:EUBELI_RS04685 ^@ http://purl.uniprot.org/uniprot/C4Z060 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/515620:EUBELI_RS07175 ^@ http://purl.uniprot.org/uniprot/C4Z298 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/515620:EUBELI_RS04835 ^@ http://purl.uniprot.org/uniprot/C4Z090 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/515620:EUBELI_RS13060 ^@ http://purl.uniprot.org/uniprot/C4Z6Y9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/515620:EUBELI_RS03490 ^@ http://purl.uniprot.org/uniprot/C4Z532 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/515620:EUBELI_RS05705 ^@ http://purl.uniprot.org/uniprot/C4Z0R4 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS03620 ^@ http://purl.uniprot.org/uniprot/C4Z560 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/515620:EUBELI_RS08510 ^@ http://purl.uniprot.org/uniprot/C4Z3T5 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/515620:EUBELI_RS03585 ^@ http://purl.uniprot.org/uniprot/C4Z552 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/515620:EUBELI_RS01575 ^@ http://purl.uniprot.org/uniprot/C4Z2V6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/515620:EUBELI_RS06095 ^@ http://purl.uniprot.org/uniprot/C4Z0Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS10970 ^@ http://purl.uniprot.org/uniprot/C4Z7J7 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/515620:EUBELI_RS03745 ^@ http://purl.uniprot.org/uniprot/C4Z586 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/515620:EUBELI_RS03320 ^@ http://purl.uniprot.org/uniprot/C4Z502 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/515620:EUBELI_RS03895 ^@ http://purl.uniprot.org/uniprot/C4Z5G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS01015 ^@ http://purl.uniprot.org/uniprot/C4Z256 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/515620:EUBELI_RS03215 ^@ http://purl.uniprot.org/uniprot/C4Z4Y1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.|||Homodimer.|||Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate. http://togogenome.org/gene/515620:EUBELI_RS09160 ^@ http://purl.uniprot.org/uniprot/C4Z4K5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS05540 ^@ http://purl.uniprot.org/uniprot/C4Z0N1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS09240 ^@ http://purl.uniprot.org/uniprot/C4Z4M2 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/515620:EUBELI_RS01350 ^@ http://purl.uniprot.org/uniprot/C4Z2R2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/515620:EUBELI_RS06130 ^@ http://purl.uniprot.org/uniprot/C4Z0Z8 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/515620:EUBELI_RS06480 ^@ http://purl.uniprot.org/uniprot/C4Z168 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/515620:EUBELI_RS00465 ^@ http://purl.uniprot.org/uniprot/C4Z1F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS00290 ^@ http://purl.uniprot.org/uniprot/C4Z1C0 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/515620:EUBELI_RS09275 ^@ http://purl.uniprot.org/uniprot/C4Z4M9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/515620:EUBELI_RS08715 ^@ http://purl.uniprot.org/uniprot/C4Z3X8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/515620:EUBELI_RS05255 ^@ http://purl.uniprot.org/uniprot/C4Z0H3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/515620:EUBELI_RS04525 ^@ http://purl.uniprot.org/uniprot/C4Z026 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/515620:EUBELI_RS12240 ^@ http://purl.uniprot.org/uniprot/C4Z6G3 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS01445 ^@ http://purl.uniprot.org/uniprot/C4Z2T1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/515620:EUBELI_RS00435 ^@ http://purl.uniprot.org/uniprot/C4Z1F0 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/515620:EUBELI_RS13775 ^@ http://purl.uniprot.org/uniprot/C4Z7P8 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Belongs to the CobT family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/515620:EUBELI_RS09225 ^@ http://purl.uniprot.org/uniprot/C4Z4L9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS13580 ^@ http://purl.uniprot.org/uniprot/C4Z036 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/515620:EUBELI_RS03590 ^@ http://purl.uniprot.org/uniprot/C4Z553 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/515620:EUBELI_RS02475 ^@ http://purl.uniprot.org/uniprot/C4Z3Q6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/515620:EUBELI_RS09950 ^@ http://purl.uniprot.org/uniprot/C4Z5E3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/515620:EUBELI_RS03665 ^@ http://purl.uniprot.org/uniprot/C4Z569 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/515620:EUBELI_RS11000 ^@ http://purl.uniprot.org/uniprot/C4Z7K3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS04250 ^@ http://purl.uniprot.org/uniprot/C4Z5M9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/515620:EUBELI_RS03990 ^@ http://purl.uniprot.org/uniprot/C4Z5I0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Cell membrane|||Membrane|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/515620:EUBELI_RS00155 ^@ http://purl.uniprot.org/uniprot/C4Z192 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS05250 ^@ http://purl.uniprot.org/uniprot/C4Z0H2 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/515620:EUBELI_RS08035 ^@ http://purl.uniprot.org/uniprot/C4Z372 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS13485 ^@ http://purl.uniprot.org/uniprot/C4Z1Z3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/515620:EUBELI_RS08275 ^@ http://purl.uniprot.org/uniprot/C4Z3C1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/515620:EUBELI_RS06620 ^@ http://purl.uniprot.org/uniprot/C4Z1K1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/515620:EUBELI_RS04310 ^@ http://purl.uniprot.org/uniprot/C4Z5P0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/515620:EUBELI_RS04645 ^@ http://purl.uniprot.org/uniprot/C4Z051 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/515620:EUBELI_RS11020 ^@ http://purl.uniprot.org/uniprot/C4Z7K7 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/515620:EUBELI_RS10560 ^@ http://purl.uniprot.org/uniprot/C4Z7A9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS13705 ^@ http://purl.uniprot.org/uniprot/C4Z3U7 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/515620:EUBELI_RS13330 ^@ http://purl.uniprot.org/uniprot/C4Z745 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/515620:EUBELI_RS02160 ^@ http://purl.uniprot.org/uniprot/C4Z3J5 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/515620:EUBELI_RS11355 ^@ http://purl.uniprot.org/uniprot/C4Z7T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS13730 ^@ http://purl.uniprot.org/uniprot/C4Z4T2 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/515620:EUBELI_RS01570 ^@ http://purl.uniprot.org/uniprot/C4Z2V5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/515620:EUBELI_RS05080 ^@ http://purl.uniprot.org/uniprot/C4Z0E0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/515620:EUBELI_RS12235 ^@ http://purl.uniprot.org/uniprot/C4Z6G2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS08565 ^@ http://purl.uniprot.org/uniprot/C4Z3U6 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/515620:EUBELI_RS00035 ^@ http://purl.uniprot.org/uniprot/C4Z178 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/515620:EUBELI_RS02760 ^@ http://purl.uniprot.org/uniprot/C4Z4A0 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/515620:EUBELI_RS02565 ^@ http://purl.uniprot.org/uniprot/C4Z460 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS01765 ^@ http://purl.uniprot.org/uniprot/C4Z2Z4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/515620:EUBELI_RS10600 ^@ http://purl.uniprot.org/uniprot/C4Z7B8 ^@ Caution|||Function ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS02860 ^@ http://purl.uniprot.org/uniprot/C4Z4C3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/515620:EUBELI_RS02650 ^@ http://purl.uniprot.org/uniprot/C4Z478 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS02365 ^@ http://purl.uniprot.org/uniprot/C4Z3N5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/515620:EUBELI_RS02110 ^@ http://purl.uniprot.org/uniprot/C4Z3I3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS10750 ^@ http://purl.uniprot.org/uniprot/C4Z7E9 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/515620:EUBELI_RS11935 ^@ http://purl.uniprot.org/uniprot/C4Z6A0 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/515620:EUBELI_RS01125 ^@ http://purl.uniprot.org/uniprot/C4Z280 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/515620:EUBELI_RS12380 ^@ http://purl.uniprot.org/uniprot/C4Z6J0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS08115 ^@ http://purl.uniprot.org/uniprot/C4Z388 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS09060 ^@ http://purl.uniprot.org/uniprot/C4Z448 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/515620:EUBELI_RS12435 ^@ http://purl.uniprot.org/uniprot/C4Z6K1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS11060 ^@ http://purl.uniprot.org/uniprot/C4Z7L7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/515620:EUBELI_RS10755 ^@ http://purl.uniprot.org/uniprot/C4Z7F0 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS06590 ^@ http://purl.uniprot.org/uniprot/C4Z1J5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/515620:EUBELI_RS11175 ^@ http://purl.uniprot.org/uniprot/C4Z7P3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS05125 ^@ http://purl.uniprot.org/uniprot/C4Z0E9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/515620:EUBELI_RS03165 ^@ http://purl.uniprot.org/uniprot/C4Z4W9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/515620:EUBELI_RS07030 ^@ http://purl.uniprot.org/uniprot/C4Z1T4 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/515620:EUBELI_RS10920 ^@ http://purl.uniprot.org/uniprot/C4Z7I7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/515620:EUBELI_RS04855 ^@ http://purl.uniprot.org/uniprot/C4Z094 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/515620:EUBELI_RS06780 ^@ http://purl.uniprot.org/uniprot/C4Z1N3 ^@ Similarity ^@ Belongs to the ThiD family. http://togogenome.org/gene/515620:EUBELI_RS12950 ^@ http://purl.uniprot.org/uniprot/C4Z6W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS11905 ^@ http://purl.uniprot.org/uniprot/C4Z694 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-ACP thioesterase family.|||chloroplast http://togogenome.org/gene/515620:EUBELI_RS07390 ^@ http://purl.uniprot.org/uniprot/C4Z2E6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HsdR family.|||Subunit R is required for both nuclease and ATPase activities, but not for modification.|||The type I restriction/modification system is composed of three polypeptides R, M and S. http://togogenome.org/gene/515620:EUBELI_RS05740 ^@ http://purl.uniprot.org/uniprot/C4Z0S1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS06905 ^@ http://purl.uniprot.org/uniprot/C4Z1Q8 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/515620:EUBELI_RS13655 ^@ http://purl.uniprot.org/uniprot/C4Z2E7 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/515620:EUBELI_RS12320 ^@ http://purl.uniprot.org/uniprot/C4Z6H8 ^@ Similarity ^@ Belongs to the UDPGP type 1 family. http://togogenome.org/gene/515620:EUBELI_RS06440 ^@ http://purl.uniprot.org/uniprot/C4Z160 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS08980 ^@ http://purl.uniprot.org/uniprot/C4Z432 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/515620:EUBELI_RS04585 ^@ http://purl.uniprot.org/uniprot/C4Z038 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/515620:EUBELI_RS04255 ^@ http://purl.uniprot.org/uniprot/C4Z5N0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/515620:EUBELI_RS01150 ^@ http://purl.uniprot.org/uniprot/C4Z285 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/515620:EUBELI_RS02145 ^@ http://purl.uniprot.org/uniprot/C4Z3J1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS06110 ^@ http://purl.uniprot.org/uniprot/C4Z0Z4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/515620:EUBELI_RS05395 ^@ http://purl.uniprot.org/uniprot/C4Z0K1 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/515620:EUBELI_RS01475 ^@ http://purl.uniprot.org/uniprot/C4Z2T7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/515620:EUBELI_RS07655 ^@ http://purl.uniprot.org/uniprot/C4Z2K9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS10045 ^@ http://purl.uniprot.org/uniprot/C4Z5U1 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/515620:EUBELI_RS04930 ^@ http://purl.uniprot.org/uniprot/C4Z0B0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/515620:EUBELI_RS08190 ^@ http://purl.uniprot.org/uniprot/C4Z3A4 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/515620:EUBELI_RS11595 ^@ http://purl.uniprot.org/uniprot/C4Z625 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/515620:EUBELI_RS07965 ^@ http://purl.uniprot.org/uniprot/C4Z358 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/515620:EUBELI_RS05260 ^@ http://purl.uniprot.org/uniprot/C4Z0H4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/515620:EUBELI_RS07750 ^@ http://purl.uniprot.org/uniprot/C4Z2M8 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/515620:EUBELI_RS01840 ^@ http://purl.uniprot.org/uniprot/C4Z309 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/515620:EUBELI_RS08735 ^@ http://purl.uniprot.org/uniprot/C4Z3Y3 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/515620:EUBELI_RS05545 ^@ http://purl.uniprot.org/uniprot/C4Z0N2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS12420 ^@ http://purl.uniprot.org/uniprot/C4Z6J8 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/515620:EUBELI_RS09555 ^@ http://purl.uniprot.org/uniprot/C4Z4T0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/515620:EUBELI_RS13590 ^@ http://purl.uniprot.org/uniprot/C4Z0I7 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/515620:EUBELI_RS02390 ^@ http://purl.uniprot.org/uniprot/C4Z3N9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/515620:EUBELI_RS08315 ^@ http://purl.uniprot.org/uniprot/C4Z3C9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS03760 ^@ http://purl.uniprot.org/uniprot/C4Z589 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/515620:EUBELI_RS03890 ^@ http://purl.uniprot.org/uniprot/C4Z5G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS11245 ^@ http://purl.uniprot.org/uniprot/C4Z7Q7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS06985 ^@ http://purl.uniprot.org/uniprot/C4Z1S4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/515620:EUBELI_RS02655 ^@ http://purl.uniprot.org/uniprot/C4Z479 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS10980 ^@ http://purl.uniprot.org/uniprot/C4Z7J9 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/515620:EUBELI_RS00905 ^@ http://purl.uniprot.org/uniprot/C4Z229 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS06955 ^@ http://purl.uniprot.org/uniprot/C4Z1R8 ^@ Similarity ^@ Belongs to the RNase H family. http://togogenome.org/gene/515620:EUBELI_RS03235 ^@ http://purl.uniprot.org/uniprot/C4Z4Y5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/515620:EUBELI_RS00265 ^@ http://purl.uniprot.org/uniprot/C4Z1B5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). http://togogenome.org/gene/515620:EUBELI_RS03070 ^@ http://purl.uniprot.org/uniprot/C4Z4G7 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/515620:EUBELI_RS04230 ^@ http://purl.uniprot.org/uniprot/C4Z5M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS05150 ^@ http://purl.uniprot.org/uniprot/C4Z0F3 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/515620:EUBELI_RS10635 ^@ http://purl.uniprot.org/uniprot/C4Z7C5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/515620:EUBELI_RS12730 ^@ http://purl.uniprot.org/uniprot/C4Z6R6 ^@ Similarity ^@ Belongs to the polypeptide deformylase family. http://togogenome.org/gene/515620:EUBELI_RS10995 ^@ http://purl.uniprot.org/uniprot/C4Z7K2 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/515620:EUBELI_RS07915 ^@ http://purl.uniprot.org/uniprot/C4Z346 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/515620:EUBELI_RS04565 ^@ http://purl.uniprot.org/uniprot/C4Z034 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS07185 ^@ http://purl.uniprot.org/uniprot/C4Z2A0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/515620:EUBELI_RS05625 ^@ http://purl.uniprot.org/uniprot/C4Z0P8 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/515620:EUBELI_RS03580 ^@ http://purl.uniprot.org/uniprot/C4Z551 ^@ Caution|||Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/515620:EUBELI_RS06305 ^@ http://purl.uniprot.org/uniprot/C4Z135 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/515620:EUBELI_RS01335 ^@ http://purl.uniprot.org/uniprot/C4Z2Q9 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/515620:EUBELI_RS06585 ^@ http://purl.uniprot.org/uniprot/C4Z1J4 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/515620:EUBELI_RS11470 ^@ http://purl.uniprot.org/uniprot/C4Z7V7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS05185 ^@ http://purl.uniprot.org/uniprot/C4Z0G0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/515620:EUBELI_RS12710 ^@ http://purl.uniprot.org/uniprot/C4Z6R1 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS02360 ^@ http://purl.uniprot.org/uniprot/C4Z3N4 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/515620:EUBELI_RS03470 ^@ http://purl.uniprot.org/uniprot/C4Z528 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/515620:EUBELI_RS07845 ^@ http://purl.uniprot.org/uniprot/C4Z332 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS12910 ^@ http://purl.uniprot.org/uniprot/C4Z6V5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS00030 ^@ http://purl.uniprot.org/uniprot/C4Z177 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/515620:EUBELI_RS02645 ^@ http://purl.uniprot.org/uniprot/C4Z477 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/515620:EUBELI_RS03150 ^@ http://purl.uniprot.org/uniprot/C4Z4I6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS05605 ^@ http://purl.uniprot.org/uniprot/C4Z0P4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS08135 ^@ http://purl.uniprot.org/uniprot/C4Z392 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS03795 ^@ http://purl.uniprot.org/uniprot/C4Z596 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS11960 ^@ http://purl.uniprot.org/uniprot/C4Z6A6 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/515620:EUBELI_RS01465 ^@ http://purl.uniprot.org/uniprot/C4Z2T5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). http://togogenome.org/gene/515620:EUBELI_RS00165 ^@ http://purl.uniprot.org/uniprot/C4Z194 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS03060 ^@ http://purl.uniprot.org/uniprot/C4Z4G5 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/515620:EUBELI_RS08895 ^@ http://purl.uniprot.org/uniprot/C4Z414 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/515620:EUBELI_RS06710 ^@ http://purl.uniprot.org/uniprot/C4Z1M0 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/515620:EUBELI_RS03645 ^@ http://purl.uniprot.org/uniprot/C4Z565 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS06310 ^@ http://purl.uniprot.org/uniprot/C4Z136 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/515620:EUBELI_RS06890 ^@ http://purl.uniprot.org/uniprot/C4Z1Q5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS04725 ^@ http://purl.uniprot.org/uniprot/C4Z068 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/515620:EUBELI_RS02485 ^@ http://purl.uniprot.org/uniprot/C4Z3Q9 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/515620:EUBELI_RS06655 ^@ http://purl.uniprot.org/uniprot/C4Z1K8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/515620:EUBELI_RS07045 ^@ http://purl.uniprot.org/uniprot/C4Z1T7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/515620:EUBELI_RS12745 ^@ http://purl.uniprot.org/uniprot/C4Z6R9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS05095 ^@ http://purl.uniprot.org/uniprot/C4Z0E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS03710 ^@ http://purl.uniprot.org/uniprot/C4Z579 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/515620:EUBELI_RS06615 ^@ http://purl.uniprot.org/uniprot/C4Z1K0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/515620:EUBELI_RS12555 ^@ http://purl.uniprot.org/uniprot/C4Z6M6 ^@ Similarity ^@ Belongs to the FBPase class 3 family. http://togogenome.org/gene/515620:EUBELI_RS13615 ^@ http://purl.uniprot.org/uniprot/C4Z149 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/515620:EUBELI_RS00250 ^@ http://purl.uniprot.org/uniprot/C4Z1B2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS06880 ^@ http://purl.uniprot.org/uniprot/C4Z1Q3 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. http://togogenome.org/gene/515620:EUBELI_RS12040 ^@ http://purl.uniprot.org/uniprot/C4Z6C1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS01360 ^@ http://purl.uniprot.org/uniprot/C4Z2R4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/515620:EUBELI_RS06750 ^@ http://purl.uniprot.org/uniprot/C4Z1M8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/515620:EUBELI_RS07645 ^@ http://purl.uniprot.org/uniprot/C4Z2K7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/515620:EUBELI_RS13020 ^@ http://purl.uniprot.org/uniprot/C4Z6Y1 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Requires K(+) for maximal activity.|||Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. http://togogenome.org/gene/515620:EUBELI_RS00320 ^@ http://purl.uniprot.org/uniprot/C4Z1C6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS03730 ^@ http://purl.uniprot.org/uniprot/C4Z583 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.|||Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS11235 ^@ http://purl.uniprot.org/uniprot/C4Z7Q5 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/515620:EUBELI_RS07205 ^@ http://purl.uniprot.org/uniprot/C4Z2A4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/515620:EUBELI_RS03910 ^@ http://purl.uniprot.org/uniprot/C4Z5G4 ^@ Similarity ^@ Belongs to the FlgD family. http://togogenome.org/gene/515620:EUBELI_RS03085 ^@ http://purl.uniprot.org/uniprot/C4Z4H0 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/515620:EUBELI_RS03410 ^@ http://purl.uniprot.org/uniprot/C4Z516 ^@ Similarity ^@ Belongs to the FtsK/SpoIIIE/SftA family. http://togogenome.org/gene/515620:EUBELI_RS09190 ^@ http://purl.uniprot.org/uniprot/C4Z4L2 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/515620:EUBELI_RS07275 ^@ http://purl.uniprot.org/uniprot/C4Z2C0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS03945 ^@ http://purl.uniprot.org/uniprot/C4Z5H1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS09410 ^@ http://purl.uniprot.org/uniprot/C4Z4Q8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class U subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/515620:EUBELI_RS05345 ^@ http://purl.uniprot.org/uniprot/C4Z0J1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/515620:EUBELI_RS10735 ^@ http://purl.uniprot.org/uniprot/C4Z7E6 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/515620:EUBELI_RS07080 ^@ http://purl.uniprot.org/uniprot/C4Z1U4 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/515620:EUBELI_RS06990 ^@ http://purl.uniprot.org/uniprot/C4Z1S5 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/515620:EUBELI_RS01540 ^@ http://purl.uniprot.org/uniprot/C4Z2V0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/515620:EUBELI_RS05765 ^@ http://purl.uniprot.org/uniprot/C4Z0S6 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/515620:EUBELI_RS05455 ^@ http://purl.uniprot.org/uniprot/C4Z0L3 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/515620:EUBELI_RS03430 ^@ http://purl.uniprot.org/uniprot/C4Z520 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/515620:EUBELI_RS09890 ^@ http://purl.uniprot.org/uniprot/C4Z5D1 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/515620:EUBELI_RS00470 ^@ http://purl.uniprot.org/uniprot/C4Z1F7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/515620:EUBELI_RS08045 ^@ http://purl.uniprot.org/uniprot/C4Z374 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/515620:EUBELI_RS03930 ^@ http://purl.uniprot.org/uniprot/C4Z5G8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS09360 ^@ http://purl.uniprot.org/uniprot/C4Z4P7 ^@ Similarity ^@ Belongs to the MecA family. http://togogenome.org/gene/515620:EUBELI_RS00015 ^@ http://purl.uniprot.org/uniprot/C4Z174 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/515620:EUBELI_RS04365 ^@ http://purl.uniprot.org/uniprot/C4Z5Q1 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/515620:EUBELI_RS06475 ^@ http://purl.uniprot.org/uniprot/C4Z167 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/515620:EUBELI_RS03755 ^@ http://purl.uniprot.org/uniprot/C4Z588 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/515620:EUBELI_RS13025 ^@ http://purl.uniprot.org/uniprot/C4Z6Y2 ^@ Similarity ^@ Belongs to the antibiotic N-acetyltransferase family. http://togogenome.org/gene/515620:EUBELI_RS02540 ^@ http://purl.uniprot.org/uniprot/C4Z455 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/515620:EUBELI_RS03505 ^@ http://purl.uniprot.org/uniprot/C4Z535 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS12150 ^@ http://purl.uniprot.org/uniprot/C4Z6E4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/515620:EUBELI_RS06940 ^@ http://purl.uniprot.org/uniprot/C4Z1R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/515620:EUBELI_RS12335 ^@ http://purl.uniprot.org/uniprot/C4Z6I1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS01195 ^@ http://purl.uniprot.org/uniprot/C4Z2N0 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/515620:EUBELI_RS06920 ^@ http://purl.uniprot.org/uniprot/C4Z1R1 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/515620:EUBELI_RS09345 ^@ http://purl.uniprot.org/uniprot/C4Z4P3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/515620:EUBELI_RS00430 ^@ http://purl.uniprot.org/uniprot/C4Z1E9 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/515620:EUBELI_RS07790 ^@ http://purl.uniprot.org/uniprot/C4Z321 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/515620:EUBELI_RS01835 ^@ http://purl.uniprot.org/uniprot/C4Z308 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein bS18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS05440 ^@ http://purl.uniprot.org/uniprot/C4Z0L0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/515620:EUBELI_RS06320 ^@ http://purl.uniprot.org/uniprot/C4Z138 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/515620:EUBELI_RS04610 ^@ http://purl.uniprot.org/uniprot/C4Z044 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/515620:EUBELI_RS03850 ^@ http://purl.uniprot.org/uniprot/C4Z5F2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/515620:EUBELI_RS01565 ^@ http://purl.uniprot.org/uniprot/C4Z2V4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/515620:EUBELI_RS05015 ^@ http://purl.uniprot.org/uniprot/C4Z0C7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/515620:EUBELI_RS08270 ^@ http://purl.uniprot.org/uniprot/C4Z3C0 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/515620:EUBELI_RS12395 ^@ http://purl.uniprot.org/uniprot/C4Z6J3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/515620:EUBELI_RS01130 ^@ http://purl.uniprot.org/uniprot/C4Z281 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/515620:EUBELI_RS08080 ^@ http://purl.uniprot.org/uniprot/C4Z381 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS11560 ^@ http://purl.uniprot.org/uniprot/C4Z7Y0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS09395 ^@ http://purl.uniprot.org/uniprot/C4Z4Q5 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS01380 ^@ http://purl.uniprot.org/uniprot/C4Z2R8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS05245 ^@ http://purl.uniprot.org/uniprot/C4Z0H1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS07910 ^@ http://purl.uniprot.org/uniprot/C4Z345 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/515620:EUBELI_RS11150 ^@ http://purl.uniprot.org/uniprot/C4Z7N8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS07345 ^@ http://purl.uniprot.org/uniprot/C4Z2D5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/515620:EUBELI_RS02530 ^@ http://purl.uniprot.org/uniprot/C4Z453 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS00460 ^@ http://purl.uniprot.org/uniprot/C4Z1F5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS12980 ^@ http://purl.uniprot.org/uniprot/C4Z6X1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS07315 ^@ http://purl.uniprot.org/uniprot/C4Z2C9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS04785 ^@ http://purl.uniprot.org/uniprot/C4Z080 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/515620:EUBELI_RS03035 ^@ http://purl.uniprot.org/uniprot/C4Z4F9 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/515620:EUBELI_RS04970 ^@ http://purl.uniprot.org/uniprot/C4Z0B8 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/515620:EUBELI_RS04925 ^@ http://purl.uniprot.org/uniprot/C4Z0A9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS05180 ^@ http://purl.uniprot.org/uniprot/C4Z0F9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS05805 ^@ http://purl.uniprot.org/uniprot/C4Z0T6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/515620:EUBELI_RS10495 ^@ http://purl.uniprot.org/uniprot/C4Z793 ^@ Similarity ^@ Belongs to the rubredoxin family. http://togogenome.org/gene/515620:EUBELI_RS01485 ^@ http://purl.uniprot.org/uniprot/C4Z2T9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/515620:EUBELI_RS03095 ^@ http://purl.uniprot.org/uniprot/C4Z4H2 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/515620:EUBELI_RS02260 ^@ http://purl.uniprot.org/uniprot/C4Z3L3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PstS family.|||Cell membrane|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Membrane|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/515620:EUBELI_RS01555 ^@ http://purl.uniprot.org/uniprot/C4Z2V3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/515620:EUBELI_RS13430 ^@ http://purl.uniprot.org/uniprot/C4Z767 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS06500 ^@ http://purl.uniprot.org/uniprot/C4Z1H5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/515620:EUBELI_RS13635 ^@ http://purl.uniprot.org/uniprot/C4Z1T9 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/515620:EUBELI_RS12390 ^@ http://purl.uniprot.org/uniprot/C4Z6J2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/515620:EUBELI_RS04320 ^@ http://purl.uniprot.org/uniprot/C4Z5P2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/515620:EUBELI_RS09390 ^@ http://purl.uniprot.org/uniprot/C4Z4Q4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/515620:EUBELI_RS07760 ^@ http://purl.uniprot.org/uniprot/C4Z315 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS11605 ^@ http://purl.uniprot.org/uniprot/C4Z627 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/515620:EUBELI_RS08925 ^@ http://purl.uniprot.org/uniprot/C4Z420 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS03635 ^@ http://purl.uniprot.org/uniprot/C4Z563 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/515620:EUBELI_RS05630 ^@ http://purl.uniprot.org/uniprot/C4Z0P9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/515620:EUBELI_RS05115 ^@ http://purl.uniprot.org/uniprot/C4Z0E7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS00380 ^@ http://purl.uniprot.org/uniprot/C4Z1D8 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/515620:EUBELI_RS01080 ^@ http://purl.uniprot.org/uniprot/C4Z270 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/515620:EUBELI_RS11620 ^@ http://purl.uniprot.org/uniprot/C4Z630 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS08965 ^@ http://purl.uniprot.org/uniprot/C4Z429 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/515620:EUBELI_RS07135 ^@ http://purl.uniprot.org/uniprot/C4Z1V4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS08290 ^@ http://purl.uniprot.org/uniprot/C4Z3C4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/515620:EUBELI_RS12775 ^@ http://purl.uniprot.org/uniprot/C4Z6S5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS03375 ^@ http://purl.uniprot.org/uniprot/C4Z508 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/515620:EUBELI_RS01435 ^@ http://purl.uniprot.org/uniprot/C4Z2S9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/515620:EUBELI_RS01330 ^@ http://purl.uniprot.org/uniprot/C4Z2Q8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/515620:EUBELI_RS09610 ^@ http://purl.uniprot.org/uniprot/C4Z4U1 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/515620:EUBELI_RS11980 ^@ http://purl.uniprot.org/uniprot/C4Z6B0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/515620:EUBELI_RS07610 ^@ http://purl.uniprot.org/uniprot/C4Z2J9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/515620:EUBELI_RS08625 ^@ http://purl.uniprot.org/uniprot/C4Z3V9 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/515620:EUBELI_RS00785 ^@ http://purl.uniprot.org/uniprot/C4Z205 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/515620:EUBELI_RS01855 ^@ http://purl.uniprot.org/uniprot/C4Z312 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/515620:EUBELI_RS05110 ^@ http://purl.uniprot.org/uniprot/C4Z0E6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/515620:EUBELI_RS13390 ^@ http://purl.uniprot.org/uniprot/C4Z758 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS09645 ^@ http://purl.uniprot.org/uniprot/C4Z4U8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/515620:EUBELI_RS09925 ^@ http://purl.uniprot.org/uniprot/C4Z5D8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS01825 ^@ http://purl.uniprot.org/uniprot/C4Z306 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS06630 ^@ http://purl.uniprot.org/uniprot/C4Z1K3 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/515620:EUBELI_RS00325 ^@ http://purl.uniprot.org/uniprot/C4Z1C7 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/515620:EUBELI_RS03680 ^@ http://purl.uniprot.org/uniprot/C4Z572 ^@ Function|||Similarity ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. http://togogenome.org/gene/515620:EUBELI_RS08125 ^@ http://purl.uniprot.org/uniprot/C4Z390 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS06365 ^@ http://purl.uniprot.org/uniprot/C4Z147 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/515620:EUBELI_RS00050 ^@ http://purl.uniprot.org/uniprot/C4Z181 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/515620:EUBELI_RS00245 ^@ http://purl.uniprot.org/uniprot/C4Z1B1 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/515620:EUBELI_RS05785 ^@ http://purl.uniprot.org/uniprot/C4Z0T0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/515620:EUBELI_RS04350 ^@ http://purl.uniprot.org/uniprot/C4Z5P8 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/515620:EUBELI_RS04750 ^@ http://purl.uniprot.org/uniprot/C4Z073 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0291 family.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS04335 ^@ http://purl.uniprot.org/uniprot/C4Z5P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS08230 ^@ http://purl.uniprot.org/uniprot/C4Z3B2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS08770 ^@ http://purl.uniprot.org/uniprot/C4Z3Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS04095 ^@ http://purl.uniprot.org/uniprot/C4Z5K1 ^@ Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/515620:EUBELI_RS12005 ^@ http://purl.uniprot.org/uniprot/C4Z6B5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS11360 ^@ http://purl.uniprot.org/uniprot/C4Z7T3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/515620:EUBELI_RS03225 ^@ http://purl.uniprot.org/uniprot/C4Z4Y3 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/515620:EUBELI_RS02085 ^@ http://purl.uniprot.org/uniprot/C4Z3H8 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/515620:EUBELI_RS05035 ^@ http://purl.uniprot.org/uniprot/C4Z0D1 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/515620:EUBELI_RS05640 ^@ http://purl.uniprot.org/uniprot/C4Z0Q1 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/515620:EUBELI_RS08700 ^@ http://purl.uniprot.org/uniprot/C4Z3X5 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/515620:EUBELI_RS03700 ^@ http://purl.uniprot.org/uniprot/C4Z577 ^@ Similarity ^@ Belongs to the UPF0297 family. http://togogenome.org/gene/515620:EUBELI_RS03715 ^@ http://purl.uniprot.org/uniprot/C4Z580 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/515620:EUBELI_RS03640 ^@ http://purl.uniprot.org/uniprot/C4Z564 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS08165 ^@ http://purl.uniprot.org/uniprot/C4Z399 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS08985 ^@ http://purl.uniprot.org/uniprot/C4Z433 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS13035 ^@ http://purl.uniprot.org/uniprot/C4Z6Y4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS12945 ^@ http://purl.uniprot.org/uniprot/C4Z6W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS00400 ^@ http://purl.uniprot.org/uniprot/C4Z1E3 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/515620:EUBELI_RS02380 ^@ http://purl.uniprot.org/uniprot/C4Z3N8 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival. http://togogenome.org/gene/515620:EUBELI_RS01720 ^@ http://purl.uniprot.org/uniprot/C4Z2Y5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/515620:EUBELI_RS05920 ^@ http://purl.uniprot.org/uniprot/C4Z0V9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/515620:EUBELI_RS05160 ^@ http://purl.uniprot.org/uniprot/C4Z0F5 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS02535 ^@ http://purl.uniprot.org/uniprot/C4Z454 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS02150 ^@ http://purl.uniprot.org/uniprot/C4Z3J3 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/515620:EUBELI_RS08910 ^@ http://purl.uniprot.org/uniprot/C4Z417 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS01800 ^@ http://purl.uniprot.org/uniprot/C4Z301 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/515620:EUBELI_RS09380 ^@ http://purl.uniprot.org/uniprot/C4Z4Q1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/515620:EUBELI_RS01795 ^@ http://purl.uniprot.org/uniprot/C4Z300 ^@ Similarity ^@ Belongs to the UPF0735 family. http://togogenome.org/gene/515620:EUBELI_RS04830 ^@ http://purl.uniprot.org/uniprot/C4Z089 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/515620:EUBELI_RS03845 ^@ http://purl.uniprot.org/uniprot/C4Z5F1 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/515620:EUBELI_RS00420 ^@ http://purl.uniprot.org/uniprot/C4Z1E7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS10485 ^@ http://purl.uniprot.org/uniprot/C4Z791 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/515620:EUBELI_RS09295 ^@ http://purl.uniprot.org/uniprot/C4Z4N3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS08820 ^@ http://purl.uniprot.org/uniprot/C4Z3Z9 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/515620:EUBELI_RS01710 ^@ http://purl.uniprot.org/uniprot/C4Z2Y3 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/515620:EUBELI_RS04825 ^@ http://purl.uniprot.org/uniprot/C4Z088 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/515620:EUBELI_RS09615 ^@ http://purl.uniprot.org/uniprot/C4Z4U2 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/515620:EUBELI_RS08710 ^@ http://purl.uniprot.org/uniprot/C4Z3X7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. http://togogenome.org/gene/515620:EUBELI_RS11460 ^@ http://purl.uniprot.org/uniprot/C4Z7V5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS09930 ^@ http://purl.uniprot.org/uniprot/C4Z5D9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpB RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpA.|||Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H). http://togogenome.org/gene/515620:EUBELI_RS14675 ^@ http://purl.uniprot.org/uniprot/C4Z3T9 ^@ Similarity ^@ Belongs to the plasmid mobilization pre family. http://togogenome.org/gene/515620:EUBELI_RS03415 ^@ http://purl.uniprot.org/uniprot/C4Z517 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS04515 ^@ http://purl.uniprot.org/uniprot/C4Z024 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/515620:EUBELI_RS01490 ^@ http://purl.uniprot.org/uniprot/C4Z2U0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/515620:EUBELI_RS07230 ^@ http://purl.uniprot.org/uniprot/C4Z2A9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/515620:EUBELI_RS03860 ^@ http://purl.uniprot.org/uniprot/C4Z5F4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/515620:EUBELI_RS12590 ^@ http://purl.uniprot.org/uniprot/C4Z6N5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS02105 ^@ http://purl.uniprot.org/uniprot/C4Z3I2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS05620 ^@ http://purl.uniprot.org/uniprot/C4Z0P7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS07000 ^@ http://purl.uniprot.org/uniprot/C4Z1S7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/515620:EUBELI_RS00125 ^@ http://purl.uniprot.org/uniprot/C4Z186 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/515620:EUBELI_RS05885 ^@ http://purl.uniprot.org/uniprot/C4Z0V2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS01940 ^@ http://purl.uniprot.org/uniprot/C4Z3F4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/515620:EUBELI_RS04775 ^@ http://purl.uniprot.org/uniprot/C4Z078 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/515620:EUBELI_RS04300 ^@ http://purl.uniprot.org/uniprot/C4Z5N8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/515620:EUBELI_RS05810 ^@ http://purl.uniprot.org/uniprot/C4Z0T7 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/515620:EUBELI_RS04075 ^@ http://purl.uniprot.org/uniprot/C4Z5J7 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS03975 ^@ http://purl.uniprot.org/uniprot/C4Z5H7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/515620:EUBELI_RS12245 ^@ http://purl.uniprot.org/uniprot/C4Z6G4 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/515620:EUBELI_RS10505 ^@ http://purl.uniprot.org/uniprot/C4Z795 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by fructose 1,6-bisphosphate (FBP).|||Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/515620:EUBELI_RS07150 ^@ http://purl.uniprot.org/uniprot/C4Z1V7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS11345 ^@ http://purl.uniprot.org/uniprot/C4Z7T0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/515620:EUBELI_RS08915 ^@ http://purl.uniprot.org/uniprot/C4Z418 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS07090 ^@ http://purl.uniprot.org/uniprot/C4Z1U6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/515620:EUBELI_RS10615 ^@ http://purl.uniprot.org/uniprot/C4Z7C1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS12655 ^@ http://purl.uniprot.org/uniprot/C4Z6Q0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/515620:EUBELI_RS12095 ^@ http://purl.uniprot.org/uniprot/C4Z6D3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS00900 ^@ http://purl.uniprot.org/uniprot/C4Z228 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/515620:EUBELI_RS02830 ^@ http://purl.uniprot.org/uniprot/C4Z4B4 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/515620:EUBELI_RS06160 ^@ http://purl.uniprot.org/uniprot/C4Z104 ^@ Similarity ^@ Belongs to the dihydrofolate reductase family. http://togogenome.org/gene/515620:EUBELI_RS06085 ^@ http://purl.uniprot.org/uniprot/C4Z0Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/515620:EUBELI_RS01495 ^@ http://purl.uniprot.org/uniprot/C4Z2U1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/515620:EUBELI_RS05570 ^@ http://purl.uniprot.org/uniprot/C4Z0N7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/515620:EUBELI_RS00680 ^@ http://purl.uniprot.org/uniprot/C4Z1Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS02025 ^@ http://purl.uniprot.org/uniprot/C4Z3G7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS00825 ^@ http://purl.uniprot.org/uniprot/C4Z213 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ApbE family.|||Cell inner membrane|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/515620:EUBELI_RS03955 ^@ http://purl.uniprot.org/uniprot/C4Z5H3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS00550 ^@ http://purl.uniprot.org/uniprot/C4Z1H3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS06185 ^@ http://purl.uniprot.org/uniprot/C4Z109 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/515620:EUBELI_RS09265 ^@ http://purl.uniprot.org/uniprot/C4Z4M7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/515620:EUBELI_RS01450 ^@ http://purl.uniprot.org/uniprot/C4Z2T2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/515620:EUBELI_RS00315 ^@ http://purl.uniprot.org/uniprot/C4Z1C5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS12075 ^@ http://purl.uniprot.org/uniprot/C4Z6C8 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/515620:EUBELI_RS00425 ^@ http://purl.uniprot.org/uniprot/C4Z1E8 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/515620:EUBELI_RS02845 ^@ http://purl.uniprot.org/uniprot/C4Z4B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS10780 ^@ http://purl.uniprot.org/uniprot/C4Z7F6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS01545 ^@ http://purl.uniprot.org/uniprot/C4Z2V1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/515620:EUBELI_RS09575 ^@ http://purl.uniprot.org/uniprot/C4Z4T4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/515620:EUBELI_RS12175 ^@ http://purl.uniprot.org/uniprot/C4Z6E9 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/515620:EUBELI_RS08310 ^@ http://purl.uniprot.org/uniprot/C4Z3C8 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/515620:EUBELI_RS04755 ^@ http://purl.uniprot.org/uniprot/C4Z074 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/515620:EUBELI_RS11955 ^@ http://purl.uniprot.org/uniprot/C4Z6A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS07025 ^@ http://purl.uniprot.org/uniprot/C4Z1T3 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/515620:EUBELI_RS01615 ^@ http://purl.uniprot.org/uniprot/C4Z2W4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/515620:EUBELI_RS07310 ^@ http://purl.uniprot.org/uniprot/C4Z2C8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS08040 ^@ http://purl.uniprot.org/uniprot/C4Z373 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/515620:EUBELI_RS03630 ^@ http://purl.uniprot.org/uniprot/C4Z562 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/515620:EUBELI_RS07615 ^@ http://purl.uniprot.org/uniprot/C4Z2K1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M3B family.|||Binds 1 zinc ion.|||Has oligopeptidase activity and degrades a variety of small bioactive peptides. http://togogenome.org/gene/515620:EUBELI_RS06565 ^@ http://purl.uniprot.org/uniprot/C4Z1J0 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/515620:EUBELI_RS11840 ^@ http://purl.uniprot.org/uniprot/C4Z679 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS13375 ^@ http://purl.uniprot.org/uniprot/C4Z755 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/515620:EUBELI_RS08620 ^@ http://purl.uniprot.org/uniprot/C4Z3V8 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/515620:EUBELI_RS09285 ^@ http://purl.uniprot.org/uniprot/C4Z4N1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/515620:EUBELI_RS08760 ^@ http://purl.uniprot.org/uniprot/C4Z3Y7 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/515620:EUBELI_RS05315 ^@ http://purl.uniprot.org/uniprot/C4Z0I5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS07675 ^@ http://purl.uniprot.org/uniprot/C4Z2L2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS02155 ^@ http://purl.uniprot.org/uniprot/C4Z3J4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/515620:EUBELI_RS03965 ^@ http://purl.uniprot.org/uniprot/C4Z5H5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/515620:EUBELI_RS05215 ^@ http://purl.uniprot.org/uniprot/C4Z0G5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS11870 ^@ http://purl.uniprot.org/uniprot/C4Z687 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS05065 ^@ http://purl.uniprot.org/uniprot/C4Z0D7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/515620:EUBELI_RS03220 ^@ http://purl.uniprot.org/uniprot/C4Z4Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS10240 ^@ http://purl.uniprot.org/uniprot/C4Z5Y6 ^@ Similarity ^@ Belongs to the RecA family. http://togogenome.org/gene/515620:EUBELI_RS09370 ^@ http://purl.uniprot.org/uniprot/C4Z4P9 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/515620:EUBELI_RS14610 ^@ http://purl.uniprot.org/uniprot/C4Z0Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Secreted http://togogenome.org/gene/515620:EUBELI_RS05780 ^@ http://purl.uniprot.org/uniprot/C4Z0S9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/515620:EUBELI_RS06980 ^@ http://purl.uniprot.org/uniprot/C4Z1S3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS11230 ^@ http://purl.uniprot.org/uniprot/C4Z7Q4 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/515620:EUBELI_RS06210 ^@ http://purl.uniprot.org/uniprot/C4Z114 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/515620:EUBELI_RS02165 ^@ http://purl.uniprot.org/uniprot/C4Z3J6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/515620:EUBELI_RS04870 ^@ http://purl.uniprot.org/uniprot/C4Z098 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/515620:EUBELI_RS07125 ^@ http://purl.uniprot.org/uniprot/C4Z1V2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS07735 ^@ http://purl.uniprot.org/uniprot/C4Z2M4 ^@ Function|||Similarity ^@ Belongs to the anti-sigma-factor family.|||Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. http://togogenome.org/gene/515620:EUBELI_RS07850 ^@ http://purl.uniprot.org/uniprot/C4Z333 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS05155 ^@ http://purl.uniprot.org/uniprot/C4Z0F4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcAL family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS01640 ^@ http://purl.uniprot.org/uniprot/C4Z2W9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ApbE family.|||Cell inner membrane|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/515620:EUBELI_RS05495 ^@ http://purl.uniprot.org/uniprot/C4Z0M1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS10315 ^@ http://purl.uniprot.org/uniprot/C4Z604 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival. http://togogenome.org/gene/515620:EUBELI_RS03575 ^@ http://purl.uniprot.org/uniprot/C4Z550 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS05070 ^@ http://purl.uniprot.org/uniprot/C4Z0D8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/515620:EUBELI_RS08215 ^@ http://purl.uniprot.org/uniprot/C4Z3A9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/515620:EUBELI_RS03690 ^@ http://purl.uniprot.org/uniprot/C4Z574 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS02395 ^@ http://purl.uniprot.org/uniprot/C4Z3P0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS09680 ^@ http://purl.uniprot.org/uniprot/C4Z4V5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS13370 ^@ http://purl.uniprot.org/uniprot/C4Z753 ^@ Similarity ^@ Belongs to the peptidase C59 family. http://togogenome.org/gene/515620:EUBELI_RS05335 ^@ http://purl.uniprot.org/uniprot/C4Z0I9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS03655 ^@ http://purl.uniprot.org/uniprot/C4Z567 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/515620:EUBELI_RS11930 ^@ http://purl.uniprot.org/uniprot/C4Z699 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/515620:EUBELI_RS01460 ^@ http://purl.uniprot.org/uniprot/C4Z2T4 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/515620:EUBELI_RS04005 ^@ http://purl.uniprot.org/uniprot/C4Z5I3 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/515620:EUBELI_RS05205 ^@ http://purl.uniprot.org/uniprot/C4Z0G3 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/515620:EUBELI_RS03390 ^@ http://purl.uniprot.org/uniprot/C4Z512 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/515620:EUBELI_RS06545 ^@ http://purl.uniprot.org/uniprot/C4Z1I4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS04315 ^@ http://purl.uniprot.org/uniprot/C4Z5P1 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/515620:EUBELI_RS11770 ^@ http://purl.uniprot.org/uniprot/C4Z664 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS12215 ^@ http://purl.uniprot.org/uniprot/C4Z6F8 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/515620:EUBELI_RS02895 ^@ http://purl.uniprot.org/uniprot/C4Z4D0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS07350 ^@ http://purl.uniprot.org/uniprot/C4Z2D7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS10985 ^@ http://purl.uniprot.org/uniprot/C4Z7K0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/515620:EUBELI_RS04845 ^@ http://purl.uniprot.org/uniprot/C4Z092 ^@ Caution|||Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS03445 ^@ http://purl.uniprot.org/uniprot/C4Z523 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/515620:EUBELI_RS09110 ^@ http://purl.uniprot.org/uniprot/C4Z4J4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/515620:EUBELI_RS09375 ^@ http://purl.uniprot.org/uniprot/C4Z4Q0 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/515620:EUBELI_RS08265 ^@ http://purl.uniprot.org/uniprot/C4Z3B9 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/515620:EUBELI_RS09720 ^@ http://purl.uniprot.org/uniprot/C4Z4W4 ^@ Similarity ^@ Belongs to the PRORSD1 family. http://togogenome.org/gene/515620:EUBELI_RS13080 ^@ http://purl.uniprot.org/uniprot/C4Z6Z3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS12955 ^@ http://purl.uniprot.org/uniprot/C4Z6W5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/515620:EUBELI_RS11810 ^@ http://purl.uniprot.org/uniprot/C4Z672 ^@ Similarity ^@ Belongs to the CpsD/CapB family. http://togogenome.org/gene/515620:EUBELI_RS02520 ^@ http://purl.uniprot.org/uniprot/C4Z451 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/515620:EUBELI_RS09805 ^@ http://purl.uniprot.org/uniprot/C4Z5B2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS07270 ^@ http://purl.uniprot.org/uniprot/C4Z2B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS10630 ^@ http://purl.uniprot.org/uniprot/C4Z7C4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS02340 ^@ http://purl.uniprot.org/uniprot/C4Z3N0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS04545 ^@ http://purl.uniprot.org/uniprot/C4Z030 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/515620:EUBELI_RS10510 ^@ http://purl.uniprot.org/uniprot/C4Z796 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/515620:EUBELI_RS07140 ^@ http://purl.uniprot.org/uniprot/C4Z1V6 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/515620:EUBELI_RS06755 ^@ http://purl.uniprot.org/uniprot/C4Z1M9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/515620:EUBELI_RS04760 ^@ http://purl.uniprot.org/uniprot/C4Z075 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS08395 ^@ http://purl.uniprot.org/uniprot/C4Z3E7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS01520 ^@ http://purl.uniprot.org/uniprot/C4Z2U6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/515620:EUBELI_RS11300 ^@ http://purl.uniprot.org/uniprot/C4Z7S0 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/515620:EUBELI_RS08680 ^@ http://purl.uniprot.org/uniprot/C4Z3X1 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS09325 ^@ http://purl.uniprot.org/uniprot/C4Z4N9 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/515620:EUBELI_RS06410 ^@ http://purl.uniprot.org/uniprot/C4Z154 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/515620:EUBELI_RS13355 ^@ http://purl.uniprot.org/uniprot/C4Z750 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/515620:EUBELI_RS04665 ^@ http://purl.uniprot.org/uniprot/C4Z055 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/515620:EUBELI_RS08485 ^@ http://purl.uniprot.org/uniprot/C4Z3T0 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/515620:EUBELI_RS11820 ^@ http://purl.uniprot.org/uniprot/C4Z674 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family. http://togogenome.org/gene/515620:EUBELI_RS02270 ^@ http://purl.uniprot.org/uniprot/C4Z3L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS07805 ^@ http://purl.uniprot.org/uniprot/C4Z324 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/515620:EUBELI_RS09760 ^@ http://purl.uniprot.org/uniprot/C4Z5A4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS05680 ^@ http://purl.uniprot.org/uniprot/C4Z0Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/515620:EUBELI_RS04615 ^@ http://purl.uniprot.org/uniprot/C4Z045 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/515620:EUBELI_RS02590 ^@ http://purl.uniprot.org/uniprot/C4Z465 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS06725 ^@ http://purl.uniprot.org/uniprot/C4Z1M3 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/515620:EUBELI_RS11015 ^@ http://purl.uniprot.org/uniprot/C4Z7K6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS05385 ^@ http://purl.uniprot.org/uniprot/C4Z0J9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS08180 ^@ http://purl.uniprot.org/uniprot/C4Z3A2 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/515620:EUBELI_RS13315 ^@ http://purl.uniprot.org/uniprot/C4Z742 ^@ Function|||Similarity ^@ Belongs to the KptA/TPT1 family.|||Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase. http://togogenome.org/gene/515620:EUBELI_RS07050 ^@ http://purl.uniprot.org/uniprot/C4Z1T8 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/515620:EUBELI_RS11365 ^@ http://purl.uniprot.org/uniprot/C4Z7T4 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/515620:EUBELI_RS06400 ^@ http://purl.uniprot.org/uniprot/C4Z152 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/515620:EUBELI_RS10305 ^@ http://purl.uniprot.org/uniprot/C4Z601 ^@ Similarity ^@ Belongs to the DNA polymerase type-A family. http://togogenome.org/gene/515620:EUBELI_RS04995 ^@ http://purl.uniprot.org/uniprot/C4Z0C3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/515620:EUBELI_RS11165 ^@ http://purl.uniprot.org/uniprot/C4Z7P1 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/515620:EUBELI_RS01805 ^@ http://purl.uniprot.org/uniprot/C4Z302 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/515620:EUBELI_RS04820 ^@ http://purl.uniprot.org/uniprot/C4Z087 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/515620:EUBELI_RS09900 ^@ http://purl.uniprot.org/uniprot/C4Z5D3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS09280 ^@ http://purl.uniprot.org/uniprot/C4Z4N0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/515620:EUBELI_RS00220 ^@ http://purl.uniprot.org/uniprot/C4Z1A6 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/515620:EUBELI_RS03705 ^@ http://purl.uniprot.org/uniprot/C4Z578 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF nuclease family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS00555 ^@ http://purl.uniprot.org/uniprot/C4Z1H4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/515620:EUBELI_RS13075 ^@ http://purl.uniprot.org/uniprot/C4Z6Z2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/515620:EUBELI_RS09870 ^@ http://purl.uniprot.org/uniprot/C4Z5C7 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/515620:EUBELI_RS00625 ^@ http://purl.uniprot.org/uniprot/C4Z1X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Secreted http://togogenome.org/gene/515620:EUBELI_RS10515 ^@ http://purl.uniprot.org/uniprot/C4Z797 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/515620:EUBELI_RS07330 ^@ http://purl.uniprot.org/uniprot/C4Z2D2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS01440 ^@ http://purl.uniprot.org/uniprot/C4Z2T0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/515620:EUBELI_RS06170 ^@ http://purl.uniprot.org/uniprot/C4Z106 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/515620:EUBELI_RS09215 ^@ http://purl.uniprot.org/uniprot/C4Z4L7 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/515620:EUBELI_RS04690 ^@ http://purl.uniprot.org/uniprot/C4Z061 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/515620:EUBELI_RS02300 ^@ http://purl.uniprot.org/uniprot/C4Z3M2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/515620:EUBELI_RS08055 ^@ http://purl.uniprot.org/uniprot/C4Z376 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/515620:EUBELI_RS07190 ^@ http://purl.uniprot.org/uniprot/C4Z2A1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS10695 ^@ http://purl.uniprot.org/uniprot/C4Z7D8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/515620:EUBELI_RS06360 ^@ http://purl.uniprot.org/uniprot/C4Z146 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/515620:EUBELI_RS09810 ^@ http://purl.uniprot.org/uniprot/C4Z5B4 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/515620:EUBELI_RS02920 ^@ http://purl.uniprot.org/uniprot/C4Z4D5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/515620:EUBELI_RS12125 ^@ http://purl.uniprot.org/uniprot/C4Z6D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS05425 ^@ http://purl.uniprot.org/uniprot/C4Z0K7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/515620:EUBELI_RS05410 ^@ http://purl.uniprot.org/uniprot/C4Z0K4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS05755 ^@ http://purl.uniprot.org/uniprot/C4Z0S4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/515620:EUBELI_RS02855 ^@ http://purl.uniprot.org/uniprot/C4Z4C2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS04065 ^@ http://purl.uniprot.org/uniprot/C4Z5J5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/515620:EUBELI_RS11195 ^@ http://purl.uniprot.org/uniprot/C4Z7P7 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/515620:EUBELI_RS07525 ^@ http://purl.uniprot.org/uniprot/C4Z2I0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS13105 ^@ http://purl.uniprot.org/uniprot/C4Z6Z8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS02430 ^@ http://purl.uniprot.org/uniprot/C4Z3P7 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/515620:EUBELI_RS07300 ^@ http://purl.uniprot.org/uniprot/C4Z2C5 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/515620:EUBELI_RS12685 ^@ http://purl.uniprot.org/uniprot/C4Z6Q6 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/515620:EUBELI_RS12540 ^@ http://purl.uniprot.org/uniprot/C4Z6M3 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/515620:EUBELI_RS04505 ^@ http://purl.uniprot.org/uniprot/C4Z022 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/515620:EUBELI_RS06330 ^@ http://purl.uniprot.org/uniprot/C4Z140 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/515620:EUBELI_RS03685 ^@ http://purl.uniprot.org/uniprot/C4Z573 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS09245 ^@ http://purl.uniprot.org/uniprot/C4Z4M3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell membrane|||Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/515620:EUBELI_RS03310 ^@ http://purl.uniprot.org/uniprot/C4Z500 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/515620:EUBELI_RS05585 ^@ http://purl.uniprot.org/uniprot/C4Z0P0 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/515620:EUBELI_RS04085 ^@ http://purl.uniprot.org/uniprot/C4Z5J9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/515620:EUBELI_RS11895 ^@ http://purl.uniprot.org/uniprot/C4Z692 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/515620:EUBELI_RS06430 ^@ http://purl.uniprot.org/uniprot/C4Z158 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/515620:EUBELI_RS05855 ^@ http://purl.uniprot.org/uniprot/C4Z0U6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/515620:EUBELI_RS02570 ^@ http://purl.uniprot.org/uniprot/C4Z461 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/515620:EUBELI_RS07500 ^@ http://purl.uniprot.org/uniprot/C4Z2H5 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/515620:EUBELI_RS09940 ^@ http://purl.uniprot.org/uniprot/C4Z5E1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/515620:EUBELI_RS12770 ^@ http://purl.uniprot.org/uniprot/C4Z6S4 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/515620:EUBELI_RS04890 ^@ http://purl.uniprot.org/uniprot/C4Z0A2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/515620:EUBELI_RS12795 ^@ http://purl.uniprot.org/uniprot/C4Z6S9 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/515620:EUBELI_RS03970 ^@ http://purl.uniprot.org/uniprot/C4Z5H6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/515620:EUBELI_RS01270 ^@ http://purl.uniprot.org/uniprot/C4Z2P5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted