http://togogenome.org/gene/519441:SMON_RS01595 ^@ http://purl.uniprot.org/uniprot/D1AWX0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/519441:SMON_RS05130 ^@ http://purl.uniprot.org/uniprot/D1AYV3 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/519441:SMON_RS01325 ^@ http://purl.uniprot.org/uniprot/D1AWR6 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/519441:SMON_RS06195 ^@ http://purl.uniprot.org/uniprot/D1AVB0 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/519441:SMON_RS00880 ^@ http://purl.uniprot.org/uniprot/D1AWI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS05550 ^@ http://purl.uniprot.org/uniprot/D1AUZ5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/519441:SMON_RS07395 ^@ http://purl.uniprot.org/uniprot/D1AVX4 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/519441:SMON_RS05630 ^@ http://purl.uniprot.org/uniprot/D1AV12 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/519441:SMON_RS01345 ^@ http://purl.uniprot.org/uniprot/D1AWS0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/519441:SMON_RS02180 ^@ http://purl.uniprot.org/uniprot/D1AX84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS01950 ^@ http://purl.uniprot.org/uniprot/D1AX41 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/519441:SMON_RS02010 ^@ http://purl.uniprot.org/uniprot/D1AX53 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/519441:SMON_RS03860 ^@ http://purl.uniprot.org/uniprot/D1AY50 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/519441:SMON_RS04850 ^@ http://purl.uniprot.org/uniprot/D1AYP9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/519441:SMON_RS05990 ^@ http://purl.uniprot.org/uniprot/D1AV78 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/519441:SMON_RS00140 ^@ http://purl.uniprot.org/uniprot/D1AW51 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell inner membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS06760 ^@ http://purl.uniprot.org/uniprot/D1AVL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/519441:SMON_RS07725 ^@ http://purl.uniprot.org/uniprot/D1AXQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS03620 ^@ http://purl.uniprot.org/uniprot/D1AY04 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/519441:SMON_RS07165 ^@ http://purl.uniprot.org/uniprot/D1AVT6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS06590 ^@ http://purl.uniprot.org/uniprot/D1AVI8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS04930 ^@ http://purl.uniprot.org/uniprot/D1AYR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS07560 ^@ http://purl.uniprot.org/uniprot/D1AW09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS06865 ^@ http://purl.uniprot.org/uniprot/D1AVM8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/519441:SMON_RS04330 ^@ http://purl.uniprot.org/uniprot/D1AYE4 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/519441:SMON_RS03455 ^@ http://purl.uniprot.org/uniprot/D1AXX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.|||Membrane http://togogenome.org/gene/519441:SMON_RS02345 ^@ http://purl.uniprot.org/uniprot/D1AXB4 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/519441:SMON_RS01635 ^@ http://purl.uniprot.org/uniprot/D1AWX8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS03785 ^@ http://purl.uniprot.org/uniprot/D1AY36 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/519441:SMON_RS00950 ^@ http://purl.uniprot.org/uniprot/D1AWK3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/519441:SMON_RS05300 ^@ http://purl.uniprot.org/uniprot/D1AUU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS07335 ^@ http://purl.uniprot.org/uniprot/D1AVW2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/519441:SMON_RS08050 ^@ http://purl.uniprot.org/uniprot/D1AYN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS00130 ^@ http://purl.uniprot.org/uniprot/D1AW49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS07055 ^@ http://purl.uniprot.org/uniprot/D1AVR5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS00585 ^@ http://purl.uniprot.org/uniprot/D1AWD4 ^@ Similarity ^@ Belongs to the polysaccharide lyase 8 family. http://togogenome.org/gene/519441:SMON_RS06940 ^@ http://purl.uniprot.org/uniprot/D1AVP3 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/519441:SMON_RS07005 ^@ http://purl.uniprot.org/uniprot/D1AVQ5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/519441:SMON_RS04070 ^@ http://purl.uniprot.org/uniprot/D1AY91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS04160 ^@ http://purl.uniprot.org/uniprot/D1AYA9 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/519441:SMON_RS05260 ^@ http://purl.uniprot.org/uniprot/D1AUU2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/519441:SMON_RS04080 ^@ http://purl.uniprot.org/uniprot/D1AY93 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/519441:SMON_RS06285 ^@ http://purl.uniprot.org/uniprot/D1AVC6 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/519441:SMON_RS02540 ^@ http://purl.uniprot.org/uniprot/D1AXF0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.|||Catalyzes the sodium-dependent transport of glutamate.|||Cell inner membrane http://togogenome.org/gene/519441:SMON_RS06345 ^@ http://purl.uniprot.org/uniprot/D1AVD8 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/519441:SMON_RS00755 ^@ http://purl.uniprot.org/uniprot/D1AWG6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS04355 ^@ http://purl.uniprot.org/uniprot/D1AYE9 ^@ Similarity ^@ Belongs to the PRORSD1 family. http://togogenome.org/gene/519441:SMON_RS02230 ^@ http://purl.uniprot.org/uniprot/D1AX89 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/519441:SMON_RS00065 ^@ http://purl.uniprot.org/uniprot/D1AW36 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/519441:SMON_RS02130 ^@ http://purl.uniprot.org/uniprot/D1AX76 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/519441:SMON_RS07525 ^@ http://purl.uniprot.org/uniprot/D1AW03 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS05505 ^@ http://purl.uniprot.org/uniprot/D1AUY6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/519441:SMON_RS04165 ^@ http://purl.uniprot.org/uniprot/D1AYB0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS03570 ^@ http://purl.uniprot.org/uniprot/D1AXZ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS05895 ^@ http://purl.uniprot.org/uniprot/D1AV59 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/519441:SMON_RS02470 ^@ http://purl.uniprot.org/uniprot/D1AXD5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/519441:SMON_RS04910 ^@ http://purl.uniprot.org/uniprot/D1AYR0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS04305 ^@ http://purl.uniprot.org/uniprot/D1AYD9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/519441:SMON_RS02545 ^@ http://purl.uniprot.org/uniprot/D1AXF1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/519441:SMON_RS01995 ^@ http://purl.uniprot.org/uniprot/D1AX50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/519441:SMON_RS01510 ^@ http://purl.uniprot.org/uniprot/D1AWV3 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/519441:SMON_RS07180 ^@ http://purl.uniprot.org/uniprot/D1AVT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS03595 ^@ http://purl.uniprot.org/uniprot/D1AXZ9 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/519441:SMON_RS07090 ^@ http://purl.uniprot.org/uniprot/D1AVS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcAL family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS06510 ^@ http://purl.uniprot.org/uniprot/D1AVH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/519441:SMON_RS04005 ^@ http://purl.uniprot.org/uniprot/D1AY79 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/519441:SMON_RS01120 ^@ http://purl.uniprot.org/uniprot/D1AWN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS00440 ^@ http://purl.uniprot.org/uniprot/D1AWA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS06200 ^@ http://purl.uniprot.org/uniprot/D1AVB1 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/519441:SMON_RS02120 ^@ http://purl.uniprot.org/uniprot/D1AX74 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS00760 ^@ http://purl.uniprot.org/uniprot/D1AWG7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/519441:SMON_RS03965 ^@ http://purl.uniprot.org/uniprot/D1AY71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/519441:SMON_RS02655 ^@ http://purl.uniprot.org/uniprot/D1AXH2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/519441:SMON_RS03205 ^@ http://purl.uniprot.org/uniprot/D1AXS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/519441:SMON_RS02880 ^@ http://purl.uniprot.org/uniprot/D1AXL5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/519441:SMON_RS04295 ^@ http://purl.uniprot.org/uniprot/D1AYD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/519441:SMON_RS01460 ^@ http://purl.uniprot.org/uniprot/D1AWU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS01910 ^@ http://purl.uniprot.org/uniprot/D1AX34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS01900 ^@ http://purl.uniprot.org/uniprot/D1AX32 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/519441:SMON_RS02555 ^@ http://purl.uniprot.org/uniprot/D1AXF3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/519441:SMON_RS01245 ^@ http://purl.uniprot.org/uniprot/D1AWQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/519441:SMON_RS04625 ^@ http://purl.uniprot.org/uniprot/D1AYK4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS03945 ^@ http://purl.uniprot.org/uniprot/D1AY67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/519441:SMON_RS01740 ^@ http://purl.uniprot.org/uniprot/D1AWZ9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/519441:SMON_RS06275 ^@ http://purl.uniprot.org/uniprot/D1AVC4 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/519441:SMON_RS06160 ^@ http://purl.uniprot.org/uniprot/D1AVA3 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS01915 ^@ http://purl.uniprot.org/uniprot/D1AX35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/519441:SMON_RS01485 ^@ http://purl.uniprot.org/uniprot/D1AWU8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/519441:SMON_RS03975 ^@ http://purl.uniprot.org/uniprot/D1AY73 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS06145 ^@ http://purl.uniprot.org/uniprot/D1AVA0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/519441:SMON_RS00910 ^@ http://purl.uniprot.org/uniprot/D1AWJ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS02585 ^@ http://purl.uniprot.org/uniprot/D1AXF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS00445 ^@ http://purl.uniprot.org/uniprot/D1AWB0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS03495 ^@ http://purl.uniprot.org/uniprot/D1AXX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS05345 ^@ http://purl.uniprot.org/uniprot/D1AUV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/519441:SMON_RS05195 ^@ http://purl.uniprot.org/uniprot/D1AUS9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/519441:SMON_RS03175 ^@ http://purl.uniprot.org/uniprot/D1AXR9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/519441:SMON_RS01185 ^@ http://purl.uniprot.org/uniprot/D1AWP5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/519441:SMON_RS07465 ^@ http://purl.uniprot.org/uniprot/D1AVZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS00520 ^@ http://purl.uniprot.org/uniprot/D1AWC3 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/519441:SMON_RS03065 ^@ http://purl.uniprot.org/uniprot/D1AXP8 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/519441:SMON_RS00785 ^@ http://purl.uniprot.org/uniprot/D1AWH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS02350 ^@ http://purl.uniprot.org/uniprot/D1AXB5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS06000 ^@ http://purl.uniprot.org/uniprot/D1AV80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/519441:SMON_RS04890 ^@ http://purl.uniprot.org/uniprot/D1AYQ7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/519441:SMON_RS03970 ^@ http://purl.uniprot.org/uniprot/D1AY72 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/519441:SMON_RS06810 ^@ http://purl.uniprot.org/uniprot/D1AVL9 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/519441:SMON_RS03465 ^@ http://purl.uniprot.org/uniprot/D1AXX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS07275 ^@ http://purl.uniprot.org/uniprot/D1AVV4 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/519441:SMON_RS01650 ^@ http://purl.uniprot.org/uniprot/D1AWY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS02415 ^@ http://purl.uniprot.org/uniprot/D1AXC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS04140 ^@ http://purl.uniprot.org/uniprot/D1AYA5 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/519441:SMON_RS03185 ^@ http://purl.uniprot.org/uniprot/D1AXS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/519441:SMON_RS01440 ^@ http://purl.uniprot.org/uniprot/D1AWT9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/519441:SMON_RS05245 ^@ http://purl.uniprot.org/uniprot/D1AUT9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/519441:SMON_RS06460 ^@ http://purl.uniprot.org/uniprot/D1AVG2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/519441:SMON_RS04180 ^@ http://purl.uniprot.org/uniprot/D1AYB3 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/519441:SMON_RS06930 ^@ http://purl.uniprot.org/uniprot/D1AVP1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/519441:SMON_RS04230 ^@ http://purl.uniprot.org/uniprot/D1AYC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS02815 ^@ http://purl.uniprot.org/uniprot/D1AXK3 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/519441:SMON_RS07530 ^@ http://purl.uniprot.org/uniprot/D1AW04 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/519441:SMON_RS01625 ^@ http://purl.uniprot.org/uniprot/D1AWX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system. http://togogenome.org/gene/519441:SMON_RS02255 ^@ http://purl.uniprot.org/uniprot/D1AX95 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/519441:SMON_RS02700 ^@ http://purl.uniprot.org/uniprot/D1AXI0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL31 family. http://togogenome.org/gene/519441:SMON_RS01720 ^@ http://purl.uniprot.org/uniprot/D1AWZ5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/519441:SMON_RS06485 ^@ http://purl.uniprot.org/uniprot/D1AVG7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/519441:SMON_RS00715 ^@ http://purl.uniprot.org/uniprot/D1AWF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS04525 ^@ http://purl.uniprot.org/uniprot/D1AYI3 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/519441:SMON_RS00225 ^@ http://purl.uniprot.org/uniprot/D1AW68 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/519441:SMON_RS03940 ^@ http://purl.uniprot.org/uniprot/D1AY66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/519441:SMON_RS07350 ^@ http://purl.uniprot.org/uniprot/D1AVW5 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/519441:SMON_RS04245 ^@ http://purl.uniprot.org/uniprot/D1AYC7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/519441:SMON_RS06890 ^@ http://purl.uniprot.org/uniprot/D1AVN3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS05800 ^@ http://purl.uniprot.org/uniprot/D1AV39 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/519441:SMON_RS05040 ^@ http://purl.uniprot.org/uniprot/D1AYT6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS01610 ^@ http://purl.uniprot.org/uniprot/D1AWX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS00460 ^@ http://purl.uniprot.org/uniprot/D1AWB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/519441:SMON_RS03280 ^@ http://purl.uniprot.org/uniprot/D1AXU0 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/519441:SMON_RS00435 ^@ http://purl.uniprot.org/uniprot/D1AWA8 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/519441:SMON_RS00945 ^@ http://purl.uniprot.org/uniprot/D1AWK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/519441:SMON_RS03235 ^@ http://purl.uniprot.org/uniprot/D1AXT1 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/519441:SMON_RS01945 ^@ http://purl.uniprot.org/uniprot/D1AX40 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M32 family.|||Binds 1 zinc ion per subunit.|||Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. http://togogenome.org/gene/519441:SMON_RS01490 ^@ http://purl.uniprot.org/uniprot/D1AWU9 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/519441:SMON_RS05225 ^@ http://purl.uniprot.org/uniprot/D1AUT5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/519441:SMON_RS05780 ^@ http://purl.uniprot.org/uniprot/D1AV35 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS03245 ^@ http://purl.uniprot.org/uniprot/D1AXT3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. http://togogenome.org/gene/519441:SMON_RS03560 ^@ http://purl.uniprot.org/uniprot/D1AXZ2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/519441:SMON_RS04705 ^@ http://purl.uniprot.org/uniprot/D1AYM0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS06990 ^@ http://purl.uniprot.org/uniprot/D1AVQ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS03195 ^@ http://purl.uniprot.org/uniprot/D1AXS3 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/519441:SMON_RS00490 ^@ http://purl.uniprot.org/uniprot/D1AWB9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/519441:SMON_RS02090 ^@ http://purl.uniprot.org/uniprot/D1AX68 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS06540 ^@ http://purl.uniprot.org/uniprot/D1AVH8 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/519441:SMON_RS03100 ^@ http://purl.uniprot.org/uniprot/D1AXQ4 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS00005 ^@ http://purl.uniprot.org/uniprot/D1AW25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/519441:SMON_RS06495 ^@ http://purl.uniprot.org/uniprot/D1AVG9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/519441:SMON_RS01200 ^@ http://purl.uniprot.org/uniprot/D1AWP7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS00905 ^@ http://purl.uniprot.org/uniprot/D1AWJ4 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/519441:SMON_RS01315 ^@ http://purl.uniprot.org/uniprot/D1AWR4 ^@ Function|||Similarity ^@ Belongs to the V-ATPase F subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/519441:SMON_RS00710 ^@ http://purl.uniprot.org/uniprot/D1AWF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS05030 ^@ http://purl.uniprot.org/uniprot/D1AYT4 ^@ Similarity ^@ Belongs to the DNase I family. http://togogenome.org/gene/519441:SMON_RS07535 ^@ http://purl.uniprot.org/uniprot/D1AW05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS05795 ^@ http://purl.uniprot.org/uniprot/D1AV38 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/519441:SMON_RS07030 ^@ http://purl.uniprot.org/uniprot/D1AVR0 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/519441:SMON_RS07810 ^@ http://purl.uniprot.org/uniprot/D1AV81 ^@ Similarity ^@ Belongs to the TrbI/VirB10 family. http://togogenome.org/gene/519441:SMON_RS05380 ^@ http://purl.uniprot.org/uniprot/D1AUW4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/519441:SMON_RS02265 ^@ http://purl.uniprot.org/uniprot/D1AX97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/519441:SMON_RS06385 ^@ http://purl.uniprot.org/uniprot/D1AVE7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/519441:SMON_RS03950 ^@ http://purl.uniprot.org/uniprot/D1AY68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS01780 ^@ http://purl.uniprot.org/uniprot/D1AX07 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS02520 ^@ http://purl.uniprot.org/uniprot/D1AXE6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/519441:SMON_RS02100 ^@ http://purl.uniprot.org/uniprot/D1AX70 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/519441:SMON_RS00545 ^@ http://purl.uniprot.org/uniprot/D1AWC8 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/519441:SMON_RS03300 ^@ http://purl.uniprot.org/uniprot/D1AXU4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/519441:SMON_RS02000 ^@ http://purl.uniprot.org/uniprot/D1AX51 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/519441:SMON_RS05830 ^@ http://purl.uniprot.org/uniprot/D1AV45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS07070 ^@ http://purl.uniprot.org/uniprot/D1AVR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS01555 ^@ http://purl.uniprot.org/uniprot/D1AWW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS03545 ^@ http://purl.uniprot.org/uniprot/D1AXY9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/519441:SMON_RS04715 ^@ http://purl.uniprot.org/uniprot/D1AYM2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS03575 ^@ http://purl.uniprot.org/uniprot/D1AXZ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS02565 ^@ http://purl.uniprot.org/uniprot/D1AXF5 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/519441:SMON_RS02510 ^@ http://purl.uniprot.org/uniprot/D1AXE4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/519441:SMON_RS00900 ^@ http://purl.uniprot.org/uniprot/D1AWJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS04215 ^@ http://purl.uniprot.org/uniprot/D1AYC1 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/519441:SMON_RS03265 ^@ http://purl.uniprot.org/uniprot/D1AXT7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/519441:SMON_RS03380 ^@ http://purl.uniprot.org/uniprot/D1AXV6 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/519441:SMON_RS03255 ^@ http://purl.uniprot.org/uniprot/D1AXT5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/519441:SMON_RS02175 ^@ http://purl.uniprot.org/uniprot/D1AX83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS04310 ^@ http://purl.uniprot.org/uniprot/D1AYE0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/519441:SMON_RS01955 ^@ http://purl.uniprot.org/uniprot/D1AX42 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/519441:SMON_RS06505 ^@ http://purl.uniprot.org/uniprot/D1AVH1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/519441:SMON_RS00550 ^@ http://purl.uniprot.org/uniprot/D1AWC9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS07120 ^@ http://purl.uniprot.org/uniprot/D1AVS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS01660 ^@ http://purl.uniprot.org/uniprot/D1AWY3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/519441:SMON_RS02485 ^@ http://purl.uniprot.org/uniprot/D1AXD8 ^@ Similarity ^@ Belongs to the RNA polymerase subunit omega family. http://togogenome.org/gene/519441:SMON_RS06140 ^@ http://purl.uniprot.org/uniprot/D1AV99 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/519441:SMON_RS01695 ^@ http://purl.uniprot.org/uniprot/D1AWZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. PolC subfamily.|||Cytoplasm|||Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/519441:SMON_RS01495 ^@ http://purl.uniprot.org/uniprot/D1AWV0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/519441:SMON_RS06445 ^@ http://purl.uniprot.org/uniprot/D1AVF9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/519441:SMON_RS05090 ^@ http://purl.uniprot.org/uniprot/D1AYU5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/519441:SMON_RS07555 ^@ http://purl.uniprot.org/uniprot/D1AW08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS01620 ^@ http://purl.uniprot.org/uniprot/D1AWX5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm|||The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/519441:SMON_RS02410 ^@ http://purl.uniprot.org/uniprot/D1AXC7 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/519441:SMON_RS05045 ^@ http://purl.uniprot.org/uniprot/D1AYT7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS07115 ^@ http://purl.uniprot.org/uniprot/D1AVS7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS03170 ^@ http://purl.uniprot.org/uniprot/D1AXR8 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/519441:SMON_RS04270 ^@ http://purl.uniprot.org/uniprot/D1AYD2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/519441:SMON_RS02590 ^@ http://purl.uniprot.org/uniprot/D1AXG0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS01285 ^@ http://purl.uniprot.org/uniprot/D1AWQ8 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.|||In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.|||In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family. http://togogenome.org/gene/519441:SMON_RS06625 ^@ http://purl.uniprot.org/uniprot/D1AVJ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS04645 ^@ http://purl.uniprot.org/uniprot/D1AYK8 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/519441:SMON_RS00385 ^@ http://purl.uniprot.org/uniprot/D1AWA0 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/519441:SMON_RS06660 ^@ http://purl.uniprot.org/uniprot/D1AVJ7 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/519441:SMON_RS02940 ^@ http://purl.uniprot.org/uniprot/D1AXM4 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/519441:SMON_RS02970 ^@ http://purl.uniprot.org/uniprot/D1AXM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS00260 ^@ http://purl.uniprot.org/uniprot/D1AW75 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/519441:SMON_RS00790 ^@ http://purl.uniprot.org/uniprot/D1AWH3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS07290 ^@ http://purl.uniprot.org/uniprot/D1AVV7 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/519441:SMON_RS05695 ^@ http://purl.uniprot.org/uniprot/D1AV22 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M3B family.|||Binds 1 zinc ion.|||Has oligopeptidase activity and degrades a variety of small bioactive peptides. http://togogenome.org/gene/519441:SMON_RS06450 ^@ http://purl.uniprot.org/uniprot/D1AVG0 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/519441:SMON_RS07485 ^@ http://purl.uniprot.org/uniprot/D1AVZ4 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/519441:SMON_RS07285 ^@ http://purl.uniprot.org/uniprot/D1AVV6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS04155 ^@ http://purl.uniprot.org/uniprot/D1AYA8 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/519441:SMON_RS00375 ^@ http://purl.uniprot.org/uniprot/D1AW98 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/519441:SMON_RS03895 ^@ http://purl.uniprot.org/uniprot/D1AY57 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/519441:SMON_RS06340 ^@ http://purl.uniprot.org/uniprot/D1AVD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS04025 ^@ http://purl.uniprot.org/uniprot/D1AY82 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/519441:SMON_RS01465 ^@ http://purl.uniprot.org/uniprot/D1AWU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/519441:SMON_RS03925 ^@ http://purl.uniprot.org/uniprot/D1AY63 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/519441:SMON_RS00310 ^@ http://purl.uniprot.org/uniprot/D1AW85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS06475 ^@ http://purl.uniprot.org/uniprot/D1AVG5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/519441:SMON_RS00670 ^@ http://purl.uniprot.org/uniprot/D1AWF1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell inner membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/519441:SMON_RS01715 ^@ http://purl.uniprot.org/uniprot/D1AWZ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/519441:SMON_RS01295 ^@ http://purl.uniprot.org/uniprot/D1AWR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/519441:SMON_RS02705 ^@ http://purl.uniprot.org/uniprot/D1AXI1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/519441:SMON_RS00470 ^@ http://purl.uniprot.org/uniprot/D1AWB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/519441:SMON_RS04710 ^@ http://purl.uniprot.org/uniprot/D1AYM1 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/519441:SMON_RS00290 ^@ http://purl.uniprot.org/uniprot/D1AW81 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/519441:SMON_RS00625 ^@ http://purl.uniprot.org/uniprot/D1AWE2 ^@ Similarity ^@ Belongs to the polysaccharide lyase 8 family. http://togogenome.org/gene/519441:SMON_RS06300 ^@ http://purl.uniprot.org/uniprot/D1AVC9 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/519441:SMON_RS02865 ^@ http://purl.uniprot.org/uniprot/D1AXL2 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/519441:SMON_RS03075 ^@ http://purl.uniprot.org/uniprot/D1AXQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS02680 ^@ http://purl.uniprot.org/uniprot/D1AXH6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/519441:SMON_RS02395 ^@ http://purl.uniprot.org/uniprot/D1AXC4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/519441:SMON_RS04765 ^@ http://purl.uniprot.org/uniprot/D1AYN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS05340 ^@ http://purl.uniprot.org/uniprot/D1AUV6 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/519441:SMON_RS04545 ^@ http://purl.uniprot.org/uniprot/D1AYI7 ^@ Similarity ^@ Belongs to the TrbG/VirB9 family. http://togogenome.org/gene/519441:SMON_RS02020 ^@ http://purl.uniprot.org/uniprot/D1AX54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/519441:SMON_RS05310 ^@ http://purl.uniprot.org/uniprot/D1AUV0 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/519441:SMON_RS00605 ^@ http://purl.uniprot.org/uniprot/D1AWD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS06945 ^@ http://purl.uniprot.org/uniprot/D1AVP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/519441:SMON_RS07445 ^@ http://purl.uniprot.org/uniprot/D1AVY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Membrane http://togogenome.org/gene/519441:SMON_RS00045 ^@ http://purl.uniprot.org/uniprot/D1AW33 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS07605 ^@ http://purl.uniprot.org/uniprot/D1AW21 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/519441:SMON_RS01645 ^@ http://purl.uniprot.org/uniprot/D1AWY0 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/519441:SMON_RS03555 ^@ http://purl.uniprot.org/uniprot/D1AXZ1 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/519441:SMON_RS05515 ^@ http://purl.uniprot.org/uniprot/D1AUY8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/519441:SMON_RS03985 ^@ http://purl.uniprot.org/uniprot/D1AY75 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/519441:SMON_RS01735 ^@ http://purl.uniprot.org/uniprot/D1AWZ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/519441:SMON_RS01050 ^@ http://purl.uniprot.org/uniprot/D1AWM3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/519441:SMON_RS07140 ^@ http://purl.uniprot.org/uniprot/D1AVT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS04470 ^@ http://purl.uniprot.org/uniprot/D1AYH1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the VapD ribonuclease family.|||Cleaves ssRNA, mostly between U:A.|||Homodimer. http://togogenome.org/gene/519441:SMON_RS04400 ^@ http://purl.uniprot.org/uniprot/D1AYF7 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/519441:SMON_RS00675 ^@ http://purl.uniprot.org/uniprot/D1AWF2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/519441:SMON_RS06520 ^@ http://purl.uniprot.org/uniprot/D1AVH4 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/519441:SMON_RS03835 ^@ http://purl.uniprot.org/uniprot/D1AY45 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/519441:SMON_RS00850 ^@ http://purl.uniprot.org/uniprot/D1AWI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS00940 ^@ http://purl.uniprot.org/uniprot/D1AUV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/519441:SMON_RS06800 ^@ http://purl.uniprot.org/uniprot/D1AVL7 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/519441:SMON_RS03490 ^@ http://purl.uniprot.org/uniprot/D1AXX7 ^@ Similarity ^@ Belongs to the NAPRTase family. http://togogenome.org/gene/519441:SMON_RS00770 ^@ http://purl.uniprot.org/uniprot/D1AWG9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS01500 ^@ http://purl.uniprot.org/uniprot/D1AWV1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein bS18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS04995 ^@ http://purl.uniprot.org/uniprot/D1AYS7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS00865 ^@ http://purl.uniprot.org/uniprot/D1AWI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS03885 ^@ http://purl.uniprot.org/uniprot/D1AY55 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/519441:SMON_RS03905 ^@ http://purl.uniprot.org/uniprot/D1AY59 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/519441:SMON_RS04090 ^@ http://purl.uniprot.org/uniprot/D1AY95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS05865 ^@ http://purl.uniprot.org/uniprot/D1AV51 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class B bacterial acid phosphatase family.|||Homotetramer.|||Periplasm http://togogenome.org/gene/519441:SMON_RS06825 ^@ http://purl.uniprot.org/uniprot/D1AVM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS01685 ^@ http://purl.uniprot.org/uniprot/D1AWY8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/519441:SMON_RS05555 ^@ http://purl.uniprot.org/uniprot/D1AUZ6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/519441:SMON_RS05730 ^@ http://purl.uniprot.org/uniprot/D1AV29 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/519441:SMON_RS04980 ^@ http://purl.uniprot.org/uniprot/D1AYS4 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by fructose 1,6-bisphosphate (FBP).|||Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/519441:SMON_RS05525 ^@ http://purl.uniprot.org/uniprot/D1AUZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/519441:SMON_RS02045 ^@ http://purl.uniprot.org/uniprot/D1AX59 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/519441:SMON_RS03625 ^@ http://purl.uniprot.org/uniprot/D1AY05 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/519441:SMON_RS03060 ^@ http://purl.uniprot.org/uniprot/D1AXP7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/519441:SMON_RS03165 ^@ http://purl.uniprot.org/uniprot/D1AXR7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/519441:SMON_RS01145 ^@ http://purl.uniprot.org/uniprot/D1AWP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/519441:SMON_RS04805 ^@ http://purl.uniprot.org/uniprot/D1AYP0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/519441:SMON_RS00190 ^@ http://purl.uniprot.org/uniprot/D1AW61 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS05370 ^@ http://purl.uniprot.org/uniprot/D1AUW2 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/519441:SMON_RS06655 ^@ http://purl.uniprot.org/uniprot/D1AVJ6 ^@ Function|||Similarity ^@ Belongs to the mannonate dehydratase family.|||Catalyzes the dehydration of D-mannonate. http://togogenome.org/gene/519441:SMON_RS04490 ^@ http://purl.uniprot.org/uniprot/D1AYH5 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/519441:SMON_RS02050 ^@ http://purl.uniprot.org/uniprot/D1AX60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell inner membrane http://togogenome.org/gene/519441:SMON_RS07360 ^@ http://purl.uniprot.org/uniprot/D1AVW7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS01380 ^@ http://purl.uniprot.org/uniprot/D1AWS7 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/519441:SMON_RS05460 ^@ http://purl.uniprot.org/uniprot/D1AUX7 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/519441:SMON_RS00145 ^@ http://purl.uniprot.org/uniprot/D1AW52 ^@ Similarity ^@ Belongs to the peptidase C15 family. http://togogenome.org/gene/519441:SMON_RS03480 ^@ http://purl.uniprot.org/uniprot/D1AXX5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS06525 ^@ http://purl.uniprot.org/uniprot/D1AVH5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/519441:SMON_RS01615 ^@ http://purl.uniprot.org/uniprot/D1AWX4 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/519441:SMON_RS00925 ^@ http://purl.uniprot.org/uniprot/D1AWJ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/519441:SMON_RS01370 ^@ http://purl.uniprot.org/uniprot/D1AWS5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS05205 ^@ http://purl.uniprot.org/uniprot/D1AUT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/519441:SMON_RS05050 ^@ http://purl.uniprot.org/uniprot/D1AYT8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/519441:SMON_RS06980 ^@ http://purl.uniprot.org/uniprot/D1AVQ0 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/519441:SMON_RS05155 ^@ http://purl.uniprot.org/uniprot/D1AYV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS05540 ^@ http://purl.uniprot.org/uniprot/D1AUZ3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/519441:SMON_RS06565 ^@ http://purl.uniprot.org/uniprot/D1AVI3 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/519441:SMON_RS00450 ^@ http://purl.uniprot.org/uniprot/D1AWB1 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/519441:SMON_RS03640 ^@ http://purl.uniprot.org/uniprot/D1AY08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS06910 ^@ http://purl.uniprot.org/uniprot/D1AVN7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/519441:SMON_RS00965 ^@ http://purl.uniprot.org/uniprot/D1AWK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS03230 ^@ http://purl.uniprot.org/uniprot/D1AXT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/519441:SMON_RS04130 ^@ http://purl.uniprot.org/uniprot/D1AYA3 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/519441:SMON_RS04810 ^@ http://purl.uniprot.org/uniprot/D1AYP1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/519441:SMON_RS04150 ^@ http://purl.uniprot.org/uniprot/D1AYA7 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/519441:SMON_RS01960 ^@ http://purl.uniprot.org/uniprot/D1AX43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS01885 ^@ http://purl.uniprot.org/uniprot/D1AX29 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/519441:SMON_RS06675 ^@ http://purl.uniprot.org/uniprot/D1AVK0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/519441:SMON_RS01055 ^@ http://purl.uniprot.org/uniprot/D1AWM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS06915 ^@ http://purl.uniprot.org/uniprot/D1AVN8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS04690 ^@ http://purl.uniprot.org/uniprot/D1AYL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS03615 ^@ http://purl.uniprot.org/uniprot/D1AY03 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/519441:SMON_RS00750 ^@ http://purl.uniprot.org/uniprot/D1AWG5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS00305 ^@ http://purl.uniprot.org/uniprot/D1AW84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS01725 ^@ http://purl.uniprot.org/uniprot/D1AWZ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/519441:SMON_RS03600 ^@ http://purl.uniprot.org/uniprot/D1AY00 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/519441:SMON_RS03190 ^@ http://purl.uniprot.org/uniprot/D1AXS2 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/519441:SMON_RS03990 ^@ http://purl.uniprot.org/uniprot/D1AY76 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/519441:SMON_RS02115 ^@ http://purl.uniprot.org/uniprot/D1AX73 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS00930 ^@ http://purl.uniprot.org/uniprot/D1AWJ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/519441:SMON_RS00630 ^@ http://purl.uniprot.org/uniprot/D1AWE3 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/519441:SMON_RS04555 ^@ http://purl.uniprot.org/uniprot/D1AYI9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS00390 ^@ http://purl.uniprot.org/uniprot/D1AWA1 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/519441:SMON_RS02830 ^@ http://purl.uniprot.org/uniprot/D1AXK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/519441:SMON_RS01665 ^@ http://purl.uniprot.org/uniprot/D1AWY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/519441:SMON_RS06260 ^@ http://purl.uniprot.org/uniprot/D1AVC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS06835 ^@ http://purl.uniprot.org/uniprot/D1AVM2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/519441:SMON_RS02760 ^@ http://purl.uniprot.org/uniprot/D1AXJ2 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/519441:SMON_RS04075 ^@ http://purl.uniprot.org/uniprot/D1AY92 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/519441:SMON_RS03675 ^@ http://purl.uniprot.org/uniprot/D1AY15 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/519441:SMON_RS06790 ^@ http://purl.uniprot.org/uniprot/D1AVL5 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/519441:SMON_RS00975 ^@ http://purl.uniprot.org/uniprot/D1AWK8 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/519441:SMON_RS02780 ^@ http://purl.uniprot.org/uniprot/D1AXJ6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/519441:SMON_RS03665 ^@ http://purl.uniprot.org/uniprot/D1AY13 ^@ Function|||Similarity ^@ Belongs to the type-2 OGG1 family.|||Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites). http://togogenome.org/gene/519441:SMON_RS05415 ^@ http://purl.uniprot.org/uniprot/D1AUW9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS00105 ^@ http://purl.uniprot.org/uniprot/D1AW44 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS03960 ^@ http://purl.uniprot.org/uniprot/D1AY70 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/519441:SMON_RS03030 ^@ http://purl.uniprot.org/uniprot/D1AXP1 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/519441:SMON_RS03690 ^@ http://purl.uniprot.org/uniprot/D1AY18 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/519441:SMON_RS05715 ^@ http://purl.uniprot.org/uniprot/D1AV26 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/519441:SMON_RS06870 ^@ http://purl.uniprot.org/uniprot/D1AVM9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/519441:SMON_RS03270 ^@ http://purl.uniprot.org/uniprot/D1AXT8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS05190 ^@ http://purl.uniprot.org/uniprot/D1AUS8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/519441:SMON_RS00325 ^@ http://purl.uniprot.org/uniprot/D1AW88 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/519441:SMON_RS00480 ^@ http://purl.uniprot.org/uniprot/D1AWB7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS01520 ^@ http://purl.uniprot.org/uniprot/D1AWV5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS01015 ^@ http://purl.uniprot.org/uniprot/D1AWL6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS01540 ^@ http://purl.uniprot.org/uniprot/D1AWV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS01415 ^@ http://purl.uniprot.org/uniprot/D1AWT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/519441:SMON_RS04040 ^@ http://purl.uniprot.org/uniprot/D1AY85 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/519441:SMON_RS02980 ^@ http://purl.uniprot.org/uniprot/D1AXN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta sliding clamp family.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS06950 ^@ http://purl.uniprot.org/uniprot/D1AVP5 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/519441:SMON_RS01730 ^@ http://purl.uniprot.org/uniprot/D1AWZ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/519441:SMON_RS04350 ^@ http://purl.uniprot.org/uniprot/D1AYE8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS06390 ^@ http://purl.uniprot.org/uniprot/D1AVE8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/519441:SMON_RS07520 ^@ http://purl.uniprot.org/uniprot/D1AW02 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/519441:SMON_RS00235 ^@ http://purl.uniprot.org/uniprot/D1AW70 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/519441:SMON_RS04960 ^@ http://purl.uniprot.org/uniprot/D1AYS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/519441:SMON_RS05615 ^@ http://purl.uniprot.org/uniprot/D1AV09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/519441:SMON_RS05200 ^@ http://purl.uniprot.org/uniprot/D1AUT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/519441:SMON_RS00595 ^@ http://purl.uniprot.org/uniprot/D1AWD6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the KduI family.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. http://togogenome.org/gene/519441:SMON_RS00155 ^@ http://purl.uniprot.org/uniprot/D1AW55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS06040 ^@ http://purl.uniprot.org/uniprot/D1AV88 ^@ Similarity ^@ Belongs to the MobA/MobL family. http://togogenome.org/gene/519441:SMON_RS00960 ^@ http://purl.uniprot.org/uniprot/D1AWK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/519441:SMON_RS02490 ^@ http://purl.uniprot.org/uniprot/D1AXD9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/519441:SMON_RS05660 ^@ http://purl.uniprot.org/uniprot/D1AV18 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/519441:SMON_RS00040 ^@ http://purl.uniprot.org/uniprot/D1AW32 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/519441:SMON_RS06490 ^@ http://purl.uniprot.org/uniprot/D1AVG8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/519441:SMON_RS01445 ^@ http://purl.uniprot.org/uniprot/D1AWU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS05420 ^@ http://purl.uniprot.org/uniprot/D1AUX0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/519441:SMON_RS04335 ^@ http://purl.uniprot.org/uniprot/D1AYE5 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS05465 ^@ http://purl.uniprot.org/uniprot/D1AUX8 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/519441:SMON_RS02695 ^@ http://purl.uniprot.org/uniprot/D1AXH9 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/519441:SMON_RS04725 ^@ http://purl.uniprot.org/uniprot/D1AYM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS03880 ^@ http://purl.uniprot.org/uniprot/D1AY54 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/519441:SMON_RS02355 ^@ http://purl.uniprot.org/uniprot/D1AXB6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS00860 ^@ http://purl.uniprot.org/uniprot/D1AWI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS07765 ^@ http://purl.uniprot.org/uniprot/D1AYI6 ^@ Similarity ^@ Belongs to the TrbI/VirB10 family. http://togogenome.org/gene/519441:SMON_RS01535 ^@ http://purl.uniprot.org/uniprot/D1AWV8 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/519441:SMON_RS02575 ^@ http://purl.uniprot.org/uniprot/D1AXF7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/519441:SMON_RS03710 ^@ http://purl.uniprot.org/uniprot/D1AY22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/519441:SMON_RS00610 ^@ http://purl.uniprot.org/uniprot/D1AWD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS07390 ^@ http://purl.uniprot.org/uniprot/D1AVX3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/519441:SMON_RS00085 ^@ http://purl.uniprot.org/uniprot/D1AW40 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/519441:SMON_RS05385 ^@ http://purl.uniprot.org/uniprot/D1AUW5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/519441:SMON_RS02605 ^@ http://purl.uniprot.org/uniprot/D1AXG3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS04790 ^@ http://purl.uniprot.org/uniprot/D1AYN7 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/519441:SMON_RS01405 ^@ http://purl.uniprot.org/uniprot/D1AWT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS01480 ^@ http://purl.uniprot.org/uniprot/D1AWU7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/519441:SMON_RS00695 ^@ http://purl.uniprot.org/uniprot/D1AWF5 ^@ Similarity ^@ Belongs to the aldolase LacD family. http://togogenome.org/gene/519441:SMON_RS04265 ^@ http://purl.uniprot.org/uniprot/D1AYD1 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/519441:SMON_RS04835 ^@ http://purl.uniprot.org/uniprot/D1AYP6 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/519441:SMON_RS05590 ^@ http://purl.uniprot.org/uniprot/D1AV04 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/519441:SMON_RS02775 ^@ http://purl.uniprot.org/uniprot/D1AXJ5 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/519441:SMON_RS06765 ^@ http://purl.uniprot.org/uniprot/D1AVL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/519441:SMON_RS03855 ^@ http://purl.uniprot.org/uniprot/D1AY49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/519441:SMON_RS04820 ^@ http://purl.uniprot.org/uniprot/D1AYP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS00330 ^@ http://purl.uniprot.org/uniprot/D1AW89 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS03820 ^@ http://purl.uniprot.org/uniprot/D1AY42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS03900 ^@ http://purl.uniprot.org/uniprot/D1AY58 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/519441:SMON_RS03780 ^@ http://purl.uniprot.org/uniprot/D1AY35 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/519441:SMON_RS02840 ^@ http://purl.uniprot.org/uniprot/D1AXK7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/519441:SMON_RS03250 ^@ http://purl.uniprot.org/uniprot/D1AXT4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/519441:SMON_RS06515 ^@ http://purl.uniprot.org/uniprot/D1AVH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/519441:SMON_RS02480 ^@ http://purl.uniprot.org/uniprot/D1AXD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/519441:SMON_RS00200 ^@ http://purl.uniprot.org/uniprot/D1AW63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/519441:SMON_RS05785 ^@ http://purl.uniprot.org/uniprot/D1AV36 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/519441:SMON_RS01060 ^@ http://purl.uniprot.org/uniprot/D1AWM5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS06465 ^@ http://purl.uniprot.org/uniprot/D1AVG3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/519441:SMON_RS04685 ^@ http://purl.uniprot.org/uniprot/D1AYL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS01965 ^@ http://purl.uniprot.org/uniprot/D1AX44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS00355 ^@ http://purl.uniprot.org/uniprot/D1AW94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS02025 ^@ http://purl.uniprot.org/uniprot/D1AX55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/519441:SMON_RS04795 ^@ http://purl.uniprot.org/uniprot/D1AYN8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/519441:SMON_RS03660 ^@ http://purl.uniprot.org/uniprot/D1AY12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/519441:SMON_RS06190 ^@ http://purl.uniprot.org/uniprot/D1AVA9 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/519441:SMON_RS02925 ^@ http://purl.uniprot.org/uniprot/D1AXM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/519441:SMON_RS05960 ^@ http://purl.uniprot.org/uniprot/D1AV72 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/519441:SMON_RS00250 ^@ http://purl.uniprot.org/uniprot/D1AW73 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS03910 ^@ http://purl.uniprot.org/uniprot/D1AY60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/519441:SMON_RS00135 ^@ http://purl.uniprot.org/uniprot/D1AW50 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS06855 ^@ http://purl.uniprot.org/uniprot/D1AVM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS01680 ^@ http://purl.uniprot.org/uniprot/D1AWY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS03445 ^@ http://purl.uniprot.org/uniprot/D1AXW8 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/519441:SMON_RS00095 ^@ http://purl.uniprot.org/uniprot/D1AW42 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/519441:SMON_RS01895 ^@ http://purl.uniprot.org/uniprot/D1AX31 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/519441:SMON_RS00995 ^@ http://purl.uniprot.org/uniprot/D1AWL3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/519441:SMON_RS01300 ^@ http://purl.uniprot.org/uniprot/D1AWR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane http://togogenome.org/gene/519441:SMON_RS05100 ^@ http://purl.uniprot.org/uniprot/D1AYU7 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/519441:SMON_RS01690 ^@ http://purl.uniprot.org/uniprot/D1AWY9 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/519441:SMON_RS04065 ^@ http://purl.uniprot.org/uniprot/D1AY90 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/519441:SMON_RS03845 ^@ http://purl.uniprot.org/uniprot/D1AY47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/519441:SMON_RS01990 ^@ http://purl.uniprot.org/uniprot/D1AX49 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS02425 ^@ http://purl.uniprot.org/uniprot/D1AXD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS00465 ^@ http://purl.uniprot.org/uniprot/D1AWB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell inner membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/519441:SMON_RS00885 ^@ http://purl.uniprot.org/uniprot/D1AWJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS02965 ^@ http://purl.uniprot.org/uniprot/D1AXM7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell inner membrane|||Probably interacts with PlsX. http://togogenome.org/gene/519441:SMON_RS03790 ^@ http://purl.uniprot.org/uniprot/D1AY37 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/519441:SMON_RS06355 ^@ http://purl.uniprot.org/uniprot/D1AVE0 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/519441:SMON_RS00370 ^@ http://purl.uniprot.org/uniprot/D1AW97 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/519441:SMON_RS03695 ^@ http://purl.uniprot.org/uniprot/D1AY19 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/519441:SMON_RS07600 ^@ http://purl.uniprot.org/uniprot/D1AW20 ^@ Similarity ^@ Belongs to the UPF0237 family. http://togogenome.org/gene/519441:SMON_RS03225 ^@ http://purl.uniprot.org/uniprot/D1AXS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/519441:SMON_RS04640 ^@ http://purl.uniprot.org/uniprot/D1AYK7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/519441:SMON_RS01135 ^@ http://purl.uniprot.org/uniprot/D1AWP0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS02475 ^@ http://purl.uniprot.org/uniprot/D1AXD6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/519441:SMON_RS05710 ^@ http://purl.uniprot.org/uniprot/D1AV25 ^@ Similarity ^@ Belongs to the GHMP kinase family. Mevalonate kinase subfamily. http://togogenome.org/gene/519441:SMON_RS07540 ^@ http://purl.uniprot.org/uniprot/D1AW06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS01110 ^@ http://purl.uniprot.org/uniprot/D1AWN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS02890 ^@ http://purl.uniprot.org/uniprot/D1AXL7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS03145 ^@ http://purl.uniprot.org/uniprot/D1AXR3 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/519441:SMON_RS02725 ^@ http://purl.uniprot.org/uniprot/D1AXI5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/519441:SMON_RS05035 ^@ http://purl.uniprot.org/uniprot/D1AYT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/519441:SMON_RS02465 ^@ http://purl.uniprot.org/uniprot/D1AXD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/519441:SMON_RS03760 ^@ http://purl.uniprot.org/uniprot/D1AY31 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/519441:SMON_RS05065 ^@ http://purl.uniprot.org/uniprot/D1AYU1 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/519441:SMON_RS02215 ^@ http://purl.uniprot.org/uniprot/D1AX86 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/519441:SMON_RS05665 ^@ http://purl.uniprot.org/uniprot/D1AV19 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/519441:SMON_RS02785 ^@ http://purl.uniprot.org/uniprot/D1AXJ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS06500 ^@ http://purl.uniprot.org/uniprot/D1AVH0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/519441:SMON_RS03220 ^@ http://purl.uniprot.org/uniprot/D1AXS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS04650 ^@ http://purl.uniprot.org/uniprot/D1AYK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/519441:SMON_RS07460 ^@ http://purl.uniprot.org/uniprot/D1AVY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS00110 ^@ http://purl.uniprot.org/uniprot/D1AW45 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/519441:SMON_RS01070 ^@ http://purl.uniprot.org/uniprot/D1AWM7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS04020 ^@ http://purl.uniprot.org/uniprot/D1AY81 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/519441:SMON_RS01835 ^@ http://purl.uniprot.org/uniprot/D1AX19 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS04170 ^@ http://purl.uniprot.org/uniprot/D1AYB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS00125 ^@ http://purl.uniprot.org/uniprot/D1AW48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS02600 ^@ http://purl.uniprot.org/uniprot/D1AXG2 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/519441:SMON_RS03305 ^@ http://purl.uniprot.org/uniprot/D1AXU5 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/519441:SMON_RS03670 ^@ http://purl.uniprot.org/uniprot/D1AY14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS05215 ^@ http://purl.uniprot.org/uniprot/D1AUT3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/519441:SMON_RS00010 ^@ http://purl.uniprot.org/uniprot/D1AW26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Membrane http://togogenome.org/gene/519441:SMON_RS07170 ^@ http://purl.uniprot.org/uniprot/D1AVT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS06335 ^@ http://purl.uniprot.org/uniprot/D1AVD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS02460 ^@ http://purl.uniprot.org/uniprot/D1AXD3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/519441:SMON_RS07230 ^@ http://purl.uniprot.org/uniprot/D1AVU6 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/519441:SMON_RS01095 ^@ http://purl.uniprot.org/uniprot/D1AWN2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/519441:SMON_RS05390 ^@ http://purl.uniprot.org/uniprot/D1AUW6 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated Cas9 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.|||Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Binds crRNA and tracrRNA. http://togogenome.org/gene/519441:SMON_RS02610 ^@ http://purl.uniprot.org/uniprot/D1AXG4 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/519441:SMON_RS03260 ^@ http://purl.uniprot.org/uniprot/D1AXT6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/519441:SMON_RS01410 ^@ http://purl.uniprot.org/uniprot/D1AWT3 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/519441:SMON_RS00455 ^@ http://purl.uniprot.org/uniprot/D1AWB2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/519441:SMON_RS00245 ^@ http://purl.uniprot.org/uniprot/D1AW72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS01865 ^@ http://purl.uniprot.org/uniprot/D1AX25 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/519441:SMON_RS07130 ^@ http://purl.uniprot.org/uniprot/D1AVS9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS03635 ^@ http://purl.uniprot.org/uniprot/D1AY07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/519441:SMON_RS02595 ^@ http://purl.uniprot.org/uniprot/D1AXG1 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/519441:SMON_RS05000 ^@ http://purl.uniprot.org/uniprot/D1AYS8 ^@ Similarity ^@ Belongs to the dihydrofolate reductase family. http://togogenome.org/gene/519441:SMON_RS06415 ^@ http://purl.uniprot.org/uniprot/D1AVF3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/519441:SMON_RS05210 ^@ http://purl.uniprot.org/uniprot/D1AUT2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/519441:SMON_RS05335 ^@ http://purl.uniprot.org/uniprot/D1AUV5 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/519441:SMON_RS04050 ^@ http://purl.uniprot.org/uniprot/D1AY87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/519441:SMON_RS01640 ^@ http://purl.uniprot.org/uniprot/D1AWX9 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/519441:SMON_RS04565 ^@ http://purl.uniprot.org/uniprot/D1AYJ1 ^@ Similarity ^@ Belongs to the MobA/MobL family. http://togogenome.org/gene/519441:SMON_RS02625 ^@ http://purl.uniprot.org/uniprot/D1AXG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/519441:SMON_RS04720 ^@ http://purl.uniprot.org/uniprot/D1AYM3 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/519441:SMON_RS06020 ^@ http://purl.uniprot.org/uniprot/D1AV85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS05605 ^@ http://purl.uniprot.org/uniprot/D1AV07 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS04780 ^@ http://purl.uniprot.org/uniprot/D1AYN5 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/519441:SMON_RS03915 ^@ http://purl.uniprot.org/uniprot/D1AY61 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/519441:SMON_RS01330 ^@ http://purl.uniprot.org/uniprot/D1AWR7 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/519441:SMON_RS04855 ^@ http://purl.uniprot.org/uniprot/D1AYQ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/519441:SMON_RS04425 ^@ http://purl.uniprot.org/uniprot/D1AYG2 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/519441:SMON_RS01700 ^@ http://purl.uniprot.org/uniprot/D1AWZ1 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/519441:SMON_RS05810 ^@ http://purl.uniprot.org/uniprot/D1AV41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS06750 ^@ http://purl.uniprot.org/uniprot/D1AVL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS06730 ^@ http://purl.uniprot.org/uniprot/D1AVK7 ^@ Similarity ^@ Belongs to the aldolase class II family. AraD/FucA subfamily. http://togogenome.org/gene/519441:SMON_RS06400 ^@ http://purl.uniprot.org/uniprot/D1AVF0 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/519441:SMON_RS03285 ^@ http://purl.uniprot.org/uniprot/D1AXU1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/519441:SMON_RS03015 ^@ http://purl.uniprot.org/uniprot/D1AXN8 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/519441:SMON_RS00890 ^@ http://purl.uniprot.org/uniprot/D1AWJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS05295 ^@ http://purl.uniprot.org/uniprot/D1AUU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/519441:SMON_RS02260 ^@ http://purl.uniprot.org/uniprot/D1AX96 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/519441:SMON_RS04655 ^@ http://purl.uniprot.org/uniprot/D1AYL0 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/519441:SMON_RS06995 ^@ http://purl.uniprot.org/uniprot/D1AVQ3 ^@ Similarity ^@ Belongs to the FtsK/SpoIIIE/SftA family. http://togogenome.org/gene/519441:SMON_RS00915 ^@ http://purl.uniprot.org/uniprot/D1AWJ6 ^@ Similarity ^@ Belongs to the peptidase C69 family. http://togogenome.org/gene/519441:SMON_RS06470 ^@ http://purl.uniprot.org/uniprot/D1AVG4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/519441:SMON_RS01065 ^@ http://purl.uniprot.org/uniprot/D1AWM6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/519441:SMON_RS04875 ^@ http://purl.uniprot.org/uniprot/D1AYQ4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/519441:SMON_RS05670 ^@ http://purl.uniprot.org/uniprot/D1AV20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/519441:SMON_RS03995 ^@ http://purl.uniprot.org/uniprot/D1AY77 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/519441:SMON_RS07610 ^@ http://purl.uniprot.org/uniprot/D1AW22 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS00935 ^@ http://purl.uniprot.org/uniprot/D1AWK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS08110 ^@ http://purl.uniprot.org/uniprot/D1AXH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ribonuclease M5 family.|||Cytoplasm|||Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. http://togogenome.org/gene/519441:SMON_RS04660 ^@ http://purl.uniprot.org/uniprot/D1AYL1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/519441:SMON_RS05220 ^@ http://purl.uniprot.org/uniprot/D1AUT4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/519441:SMON_RS01175 ^@ http://purl.uniprot.org/uniprot/D1AWP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/519441:SMON_RS05545 ^@ http://purl.uniprot.org/uniprot/D1AUZ4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/519441:SMON_RS06440 ^@ http://purl.uniprot.org/uniprot/D1AVF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/519441:SMON_RS07210 ^@ http://purl.uniprot.org/uniprot/D1AVU4 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/519441:SMON_RS02735 ^@ http://purl.uniprot.org/uniprot/D1AXI7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/519441:SMON_RS03745 ^@ http://purl.uniprot.org/uniprot/D1AY29 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS04015 ^@ http://purl.uniprot.org/uniprot/D1AY80 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/519441:SMON_RS01350 ^@ http://purl.uniprot.org/uniprot/D1AWS1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure. http://togogenome.org/gene/519441:SMON_RS03385 ^@ http://purl.uniprot.org/uniprot/D1AXV7 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/519441:SMON_RS04630 ^@ http://purl.uniprot.org/uniprot/D1AYK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/519441:SMON_RS05600 ^@ http://purl.uniprot.org/uniprot/D1AV06 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS02560 ^@ http://purl.uniprot.org/uniprot/D1AXF4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/519441:SMON_RS05575 ^@ http://purl.uniprot.org/uniprot/D1AV01 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/519441:SMON_RS02515 ^@ http://purl.uniprot.org/uniprot/D1AXE5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/519441:SMON_RS07495 ^@ http://purl.uniprot.org/uniprot/D1AVZ6 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/519441:SMON_RS01805 ^@ http://purl.uniprot.org/uniprot/D1AX12 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/519441:SMON_RS01840 ^@ http://purl.uniprot.org/uniprot/D1AX20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/519441:SMON_RS04175 ^@ http://purl.uniprot.org/uniprot/D1AYB2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/519441:SMON_RS00275 ^@ http://purl.uniprot.org/uniprot/D1AW78 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/519441:SMON_RS06570 ^@ http://purl.uniprot.org/uniprot/D1AVI4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. HMG-CoA synthase family. http://togogenome.org/gene/519441:SMON_RS04975 ^@ http://purl.uniprot.org/uniprot/D1AYS3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/519441:SMON_RS02615 ^@ http://purl.uniprot.org/uniprot/D1AXG5 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/519441:SMON_RS01570 ^@ http://purl.uniprot.org/uniprot/D1AWW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS04275 ^@ http://purl.uniprot.org/uniprot/D1AYD3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GroES chaperonin family.|||Heptamer of 7 subunits arranged in a ring.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/519441:SMON_RS02420 ^@ http://purl.uniprot.org/uniprot/D1AXC9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/519441:SMON_RS03680 ^@ http://purl.uniprot.org/uniprot/D1AY16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/519441:SMON_RS03470 ^@ http://purl.uniprot.org/uniprot/D1AXX3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS05475 ^@ http://purl.uniprot.org/uniprot/D1AUY0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS03865 ^@ http://purl.uniprot.org/uniprot/D1AY51 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/519441:SMON_RS02670 ^@ http://purl.uniprot.org/uniprot/D1AXH4 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/519441:SMON_RS05365 ^@ http://purl.uniprot.org/uniprot/D1AUW1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/519441:SMON_RS02495 ^@ http://purl.uniprot.org/uniprot/D1AXE0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/519441:SMON_RS05425 ^@ http://purl.uniprot.org/uniprot/D1AUX1 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/519441:SMON_RS01745 ^@ http://purl.uniprot.org/uniprot/D1AX00 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/519441:SMON_RS08325 ^@ http://purl.uniprot.org/uniprot/D1AW96 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/519441:SMON_RS00795 ^@ http://purl.uniprot.org/uniprot/D1AWH4 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/519441:SMON_RS03805 ^@ http://purl.uniprot.org/uniprot/D1AY40 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/519441:SMON_RS03930 ^@ http://purl.uniprot.org/uniprot/D1AY64 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/519441:SMON_RS03605 ^@ http://purl.uniprot.org/uniprot/D1AY01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS06620 ^@ http://purl.uniprot.org/uniprot/D1AVJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/519441:SMON_RS00895 ^@ http://purl.uniprot.org/uniprot/D1AWJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arginine deiminase family.|||Cytoplasm http://togogenome.org/gene/519441:SMON_RS00955 ^@ http://purl.uniprot.org/uniprot/D1AWK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/519441:SMON_RS03875 ^@ http://purl.uniprot.org/uniprot/D1AY53 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/519441:SMON_RS01240 ^@ http://purl.uniprot.org/uniprot/D1AWQ5 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/519441:SMON_RS05705 ^@ http://purl.uniprot.org/uniprot/D1AV24 ^@ Similarity ^@ Belongs to the diphosphomevalonate decarboxylase family. http://togogenome.org/gene/519441:SMON_RS02975 ^@ http://purl.uniprot.org/uniprot/D1AXM9 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/519441:SMON_RS00165 ^@ http://purl.uniprot.org/uniprot/D1AW57 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/519441:SMON_RS07375 ^@ http://purl.uniprot.org/uniprot/D1AVX0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/519441:SMON_RS00210 ^@ http://purl.uniprot.org/uniprot/D1AW65 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/519441:SMON_RS03755 ^@ http://purl.uniprot.org/uniprot/D1AY30 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/519441:SMON_RS06230 ^@ http://purl.uniprot.org/uniprot/D1AVB5 ^@ Subcellular Location Annotation ^@ Membrane