http://togogenome.org/gene/562970:BTUS_RS01595 ^@ http://purl.uniprot.org/uniprot/D5WSY5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS06980 ^@ http://purl.uniprot.org/uniprot/D5WY55 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/562970:BTUS_RS01940 ^@ http://purl.uniprot.org/uniprot/D5WT51 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS07860 ^@ http://purl.uniprot.org/uniprot/D5WPN0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS12120 ^@ http://purl.uniprot.org/uniprot/D5WSR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the spermidine/spermine synthase family.|||Cell membrane http://togogenome.org/gene/562970:BTUS_RS16085 ^@ http://purl.uniprot.org/uniprot/D5WX63 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/562970:BTUS_RS10765 ^@ http://purl.uniprot.org/uniprot/D5WR87 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/562970:BTUS_RS00055 ^@ http://purl.uniprot.org/uniprot/D5WQZ9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/562970:BTUS_RS10120 ^@ http://purl.uniprot.org/uniprot/D5WQU0 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/562970:BTUS_RS10155 ^@ http://purl.uniprot.org/uniprot/D5WQU7 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/562970:BTUS_RS00695 ^@ http://purl.uniprot.org/uniprot/D5WRP8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/562970:BTUS_RS02545 ^@ http://purl.uniprot.org/uniprot/D5WTV4 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/562970:BTUS_RS08085 ^@ http://purl.uniprot.org/uniprot/D5WPS6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/562970:BTUS_RS12400 ^@ http://purl.uniprot.org/uniprot/D5WSW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS11770 ^@ http://purl.uniprot.org/uniprot/D5WSJ2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS09000 ^@ http://purl.uniprot.org/uniprot/D5WQ91 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/562970:BTUS_RS12615 ^@ http://purl.uniprot.org/uniprot/D5WTD9 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/562970:BTUS_RS07435 ^@ http://purl.uniprot.org/uniprot/D5WPE8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/562970:BTUS_RS09255 ^@ http://purl.uniprot.org/uniprot/D5WQE3 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/562970:BTUS_RS04890 ^@ http://purl.uniprot.org/uniprot/D5WW76 ^@ Similarity ^@ Belongs to the 4-hydroxy-2-oxovalerate aldolase family. http://togogenome.org/gene/562970:BTUS_RS05020 ^@ http://purl.uniprot.org/uniprot/D5WWN3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS02500 ^@ http://purl.uniprot.org/uniprot/D5WTU4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/562970:BTUS_RS16550 ^@ http://purl.uniprot.org/uniprot/D5WXT1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/562970:BTUS_RS00035 ^@ http://purl.uniprot.org/uniprot/D5WQZ8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/562970:BTUS_RS09295 ^@ http://purl.uniprot.org/uniprot/D5WQF1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS00070 ^@ http://purl.uniprot.org/uniprot/D5WR03 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/562970:BTUS_RS00535 ^@ http://purl.uniprot.org/uniprot/D5WRL8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS13795 ^@ http://purl.uniprot.org/uniprot/D5WUT0 ^@ Similarity ^@ Belongs to the transposase IS21/IS408/IS1162 family. http://togogenome.org/gene/562970:BTUS_RS06925 ^@ http://purl.uniprot.org/uniprot/D5WY46 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/562970:BTUS_RS09475 ^@ http://purl.uniprot.org/uniprot/D5WQI3 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS07190 ^@ http://purl.uniprot.org/uniprot/D5WP98 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS03220 ^@ http://purl.uniprot.org/uniprot/D5WUL0 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/562970:BTUS_RS01340 ^@ http://purl.uniprot.org/uniprot/D5WSF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS17175 ^@ http://purl.uniprot.org/uniprot/D5WWH4 ^@ Function ^@ Required for transformation and DNA binding. http://togogenome.org/gene/562970:BTUS_RS01030 ^@ http://purl.uniprot.org/uniprot/D5WS92 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS05040 ^@ http://purl.uniprot.org/uniprot/D5WWN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS10545 ^@ http://purl.uniprot.org/uniprot/D5WR50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS03800 ^@ http://purl.uniprot.org/uniprot/D5WVA1 ^@ Similarity ^@ Belongs to the Bcl-2 family. http://togogenome.org/gene/562970:BTUS_RS11740 ^@ http://purl.uniprot.org/uniprot/D5WSI6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/562970:BTUS_RS03420 ^@ http://purl.uniprot.org/uniprot/D5WUP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS02550 ^@ http://purl.uniprot.org/uniprot/D5WTV5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. NagD family.|||Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.|||Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/562970:BTUS_RS16165 ^@ http://purl.uniprot.org/uniprot/D5WX78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS07815 ^@ http://purl.uniprot.org/uniprot/D5WPM1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/562970:BTUS_RS00065 ^@ http://purl.uniprot.org/uniprot/D5WR02 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/562970:BTUS_RS07305 ^@ http://purl.uniprot.org/uniprot/D5WPC1 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/562970:BTUS_RS11065 ^@ http://purl.uniprot.org/uniprot/D5WRE8 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS16190 ^@ http://purl.uniprot.org/uniprot/D5WX83 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/562970:BTUS_RS14095 ^@ http://purl.uniprot.org/uniprot/D5WUY8 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/562970:BTUS_RS00390 ^@ http://purl.uniprot.org/uniprot/D5WRJ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/562970:BTUS_RS04975 ^@ http://purl.uniprot.org/uniprot/D5WWM5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/562970:BTUS_RS10935 ^@ http://purl.uniprot.org/uniprot/D5WRC1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/562970:BTUS_RS12485 ^@ http://purl.uniprot.org/uniprot/D5WTB3 ^@ Similarity ^@ Belongs to the GcvH family. http://togogenome.org/gene/562970:BTUS_RS02355 ^@ http://purl.uniprot.org/uniprot/D5WTR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS00330 ^@ http://purl.uniprot.org/uniprot/D5WRH8 ^@ Similarity ^@ Belongs to the alpha/beta-type SASP family. http://togogenome.org/gene/562970:BTUS_RS12100 ^@ http://purl.uniprot.org/uniprot/D5WSQ5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/562970:BTUS_RS07175 ^@ http://purl.uniprot.org/uniprot/D5WP95 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/562970:BTUS_RS06000 ^@ http://purl.uniprot.org/uniprot/D5WXL2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS00925 ^@ http://purl.uniprot.org/uniprot/D5WS71 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/562970:BTUS_RS15300 ^@ http://purl.uniprot.org/uniprot/D5WWC6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/562970:BTUS_RS08535 ^@ http://purl.uniprot.org/uniprot/D5WQ12 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/562970:BTUS_RS07115 ^@ http://purl.uniprot.org/uniprot/D5WP82 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/562970:BTUS_RS11200 ^@ http://purl.uniprot.org/uniprot/D5WRV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS09025 ^@ http://purl.uniprot.org/uniprot/D5WQ97 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/562970:BTUS_RS03185 ^@ http://purl.uniprot.org/uniprot/D5WUK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/562970:BTUS_RS15210 ^@ http://purl.uniprot.org/uniprot/D5WWA8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS11000 ^@ http://purl.uniprot.org/uniprot/D5WRD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/562970:BTUS_RS14275 ^@ http://purl.uniprot.org/uniprot/D5WV16 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/562970:BTUS_RS07185 ^@ http://purl.uniprot.org/uniprot/D5WP97 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/562970:BTUS_RS09435 ^@ http://purl.uniprot.org/uniprot/D5WQH5 ^@ Function ^@ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. http://togogenome.org/gene/562970:BTUS_RS13615 ^@ http://purl.uniprot.org/uniprot/D5WUB6 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/562970:BTUS_RS10635 ^@ http://purl.uniprot.org/uniprot/D5WR67 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/562970:BTUS_RS16435 ^@ http://purl.uniprot.org/uniprot/D5WXC6 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/562970:BTUS_RS02165 ^@ http://purl.uniprot.org/uniprot/D5WT92 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/562970:BTUS_RS01110 ^@ http://purl.uniprot.org/uniprot/D5WSA8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/562970:BTUS_RS05310 ^@ http://purl.uniprot.org/uniprot/D5WWU3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/562970:BTUS_RS02740 ^@ http://purl.uniprot.org/uniprot/D5WTY9 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/562970:BTUS_RS09690 ^@ http://purl.uniprot.org/uniprot/D5WQL9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/562970:BTUS_RS16175 ^@ http://purl.uniprot.org/uniprot/D5WX80 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/562970:BTUS_RS00970 ^@ http://purl.uniprot.org/uniprot/D5WS80 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/562970:BTUS_RS08245 ^@ http://purl.uniprot.org/uniprot/D5WPV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS08670 ^@ http://purl.uniprot.org/uniprot/D5WQ37 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HsdR family.|||Subunit R is required for both nuclease and ATPase activities, but not for modification.|||The type I restriction/modification system is composed of three polypeptides R, M and S. http://togogenome.org/gene/562970:BTUS_RS00880 ^@ http://purl.uniprot.org/uniprot/D5WS62 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/562970:BTUS_RS02970 ^@ http://purl.uniprot.org/uniprot/D5WUG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS02135 ^@ http://purl.uniprot.org/uniprot/D5WT86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS14700 ^@ http://purl.uniprot.org/uniprot/D5WVN2 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/562970:BTUS_RS11210 ^@ http://purl.uniprot.org/uniprot/D5WRV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS14150 ^@ http://purl.uniprot.org/uniprot/D5WUZ8 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/562970:BTUS_RS00505 ^@ http://purl.uniprot.org/uniprot/D5WRL2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/562970:BTUS_RS01360 ^@ http://purl.uniprot.org/uniprot/D5WSF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS01650 ^@ http://purl.uniprot.org/uniprot/D5WSZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Belongs to the CitM (TC 2.A.11) transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS16060 ^@ http://purl.uniprot.org/uniprot/D5WX58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/562970:BTUS_RS03360 ^@ http://purl.uniprot.org/uniprot/D5WUN6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS00360 ^@ http://purl.uniprot.org/uniprot/D5WRI4 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/562970:BTUS_RS14495 ^@ http://purl.uniprot.org/uniprot/D5WVJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS06475 ^@ http://purl.uniprot.org/uniprot/D5WXW5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS09315 ^@ http://purl.uniprot.org/uniprot/D5WQF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsL family.|||Cell membrane|||Essential cell division protein.|||Membrane http://togogenome.org/gene/562970:BTUS_RS14020 ^@ http://purl.uniprot.org/uniprot/D5WUX3 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/562970:BTUS_RS08490 ^@ http://purl.uniprot.org/uniprot/D5WQ03 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/562970:BTUS_RS05070 ^@ http://purl.uniprot.org/uniprot/D5WWP3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS13815 ^@ http://purl.uniprot.org/uniprot/D5WUT4 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/562970:BTUS_RS14490 ^@ http://purl.uniprot.org/uniprot/D5WVI9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS05715 ^@ http://purl.uniprot.org/uniprot/D5WXF5 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/562970:BTUS_RS01040 ^@ http://purl.uniprot.org/uniprot/D5WS93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS15180 ^@ http://purl.uniprot.org/uniprot/D5WWA2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/562970:BTUS_RS09110 ^@ http://purl.uniprot.org/uniprot/D5WQB4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers. http://togogenome.org/gene/562970:BTUS_RS12620 ^@ http://purl.uniprot.org/uniprot/D5WTE0 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/562970:BTUS_RS09920 ^@ http://purl.uniprot.org/uniprot/D5WQQ6 ^@ Function|||Subcellular Location Annotation ^@ Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS16285 ^@ http://purl.uniprot.org/uniprot/D5WXA2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS15470 ^@ http://purl.uniprot.org/uniprot/D5WWF7 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/562970:BTUS_RS15615 ^@ http://purl.uniprot.org/uniprot/D5WWI7 ^@ Similarity ^@ Belongs to the peptidase M42 family. http://togogenome.org/gene/562970:BTUS_RS00345 ^@ http://purl.uniprot.org/uniprot/D5WRI1 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/562970:BTUS_RS14135 ^@ http://purl.uniprot.org/uniprot/D5WUZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/562970:BTUS_RS04095 ^@ http://purl.uniprot.org/uniprot/D5WVF6 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/562970:BTUS_RS00960 ^@ http://purl.uniprot.org/uniprot/D5WS78 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/562970:BTUS_RS02605 ^@ http://purl.uniprot.org/uniprot/D5WTW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS16300 ^@ http://purl.uniprot.org/uniprot/D5WXA4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/562970:BTUS_RS00965 ^@ http://purl.uniprot.org/uniprot/D5WS79 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/562970:BTUS_RS11015 ^@ http://purl.uniprot.org/uniprot/D5WRD7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/562970:BTUS_RS07390 ^@ http://purl.uniprot.org/uniprot/D5WPD9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/562970:BTUS_RS14430 ^@ http://purl.uniprot.org/uniprot/D5WV46 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/562970:BTUS_RS01440 ^@ http://purl.uniprot.org/uniprot/D5WSH4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS14535 ^@ http://purl.uniprot.org/uniprot/D5WVJ8 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/562970:BTUS_RS00805 ^@ http://purl.uniprot.org/uniprot/D5WRS1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/562970:BTUS_RS05720 ^@ http://purl.uniprot.org/uniprot/D5WXF6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS07260 ^@ http://purl.uniprot.org/uniprot/D5WPB2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/562970:BTUS_RS13720 ^@ http://purl.uniprot.org/uniprot/D5WUD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS17195 ^@ http://purl.uniprot.org/uniprot/D5WWK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS09280 ^@ http://purl.uniprot.org/uniprot/D5WQE8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS16450 ^@ http://purl.uniprot.org/uniprot/D5WXC9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/562970:BTUS_RS02795 ^@ http://purl.uniprot.org/uniprot/D5WTZ9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/562970:BTUS_RS14025 ^@ http://purl.uniprot.org/uniprot/D5WUX4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/562970:BTUS_RS04615 ^@ http://purl.uniprot.org/uniprot/D5WW27 ^@ Similarity ^@ Belongs to the PemK/MazF family. http://togogenome.org/gene/562970:BTUS_RS06635 ^@ http://purl.uniprot.org/uniprot/D5WXZ7 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/562970:BTUS_RS10800 ^@ http://purl.uniprot.org/uniprot/D5WR94 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/562970:BTUS_RS16455 ^@ http://purl.uniprot.org/uniprot/D5WXD0 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/562970:BTUS_RS15880 ^@ http://purl.uniprot.org/uniprot/D5WX21 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/562970:BTUS_RS10410 ^@ http://purl.uniprot.org/uniprot/D5WR25 ^@ Similarity ^@ Belongs to the TmoD/XamoD family. http://togogenome.org/gene/562970:BTUS_RS00375 ^@ http://purl.uniprot.org/uniprot/D5WRI7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/562970:BTUS_RS15085 ^@ http://purl.uniprot.org/uniprot/D5WVV5 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/562970:BTUS_RS14360 ^@ http://purl.uniprot.org/uniprot/D5WV32 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/562970:BTUS_RS00940 ^@ http://purl.uniprot.org/uniprot/D5WS74 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/562970:BTUS_RS17010 ^@ http://purl.uniprot.org/uniprot/D5WTG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS12980 ^@ http://purl.uniprot.org/uniprot/D5WTK9 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS03855 ^@ http://purl.uniprot.org/uniprot/D5WVB3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/562970:BTUS_RS06685 ^@ http://purl.uniprot.org/uniprot/D5WY06 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/562970:BTUS_RS02800 ^@ http://purl.uniprot.org/uniprot/D5WU00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS15365 ^@ http://purl.uniprot.org/uniprot/D5WWD6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS07955 ^@ http://purl.uniprot.org/uniprot/D5WPQ0 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/562970:BTUS_RS03710 ^@ http://purl.uniprot.org/uniprot/D5WV85 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/562970:BTUS_RS11850 ^@ http://purl.uniprot.org/uniprot/D5WSK6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS12310 ^@ http://purl.uniprot.org/uniprot/D5WSU7 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/562970:BTUS_RS11300 ^@ http://purl.uniprot.org/uniprot/D5WRX2 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/562970:BTUS_RS04990 ^@ http://purl.uniprot.org/uniprot/D5WWM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS07235 ^@ http://purl.uniprot.org/uniprot/D5WPA7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/562970:BTUS_RS06425 ^@ http://purl.uniprot.org/uniprot/D5WXV6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS03445 ^@ http://purl.uniprot.org/uniprot/D5WUQ3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/562970:BTUS_RS14440 ^@ http://purl.uniprot.org/uniprot/D5WV48 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/562970:BTUS_RS14280 ^@ http://purl.uniprot.org/uniprot/D5WV17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS09360 ^@ http://purl.uniprot.org/uniprot/D5WQG4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/562970:BTUS_RS13125 ^@ http://purl.uniprot.org/uniprot/D5WU22 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/562970:BTUS_RS03875 ^@ http://purl.uniprot.org/uniprot/D5WVB6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the flotillin-like FloA family.|||Cell membrane|||Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.|||Homooligomerizes.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane raft http://togogenome.org/gene/562970:BTUS_RS07575 ^@ http://purl.uniprot.org/uniprot/D5WPH5 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/562970:BTUS_RS07290 ^@ http://purl.uniprot.org/uniprot/D5WPB8 ^@ Similarity ^@ Belongs to the ETF-QO/FixC family. http://togogenome.org/gene/562970:BTUS_RS07065 ^@ http://purl.uniprot.org/uniprot/D5WP72 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/562970:BTUS_RS05680 ^@ http://purl.uniprot.org/uniprot/D5WXE7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS16100 ^@ http://purl.uniprot.org/uniprot/D5WX66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/562970:BTUS_RS09480 ^@ http://purl.uniprot.org/uniprot/D5WQI4 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/562970:BTUS_RS00295 ^@ http://purl.uniprot.org/uniprot/D5WRH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/562970:BTUS_RS08965 ^@ http://purl.uniprot.org/uniprot/D5WQ83 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/562970:BTUS_RS07800 ^@ http://purl.uniprot.org/uniprot/D5WPL8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS11110 ^@ http://purl.uniprot.org/uniprot/D5WRT7 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/562970:BTUS_RS00745 ^@ http://purl.uniprot.org/uniprot/D5WRQ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/562970:BTUS_RS08745 ^@ http://purl.uniprot.org/uniprot/D5WQ50 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/562970:BTUS_RS15540 ^@ http://purl.uniprot.org/uniprot/D5WWH2 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/562970:BTUS_RS01510 ^@ http://purl.uniprot.org/uniprot/D5WSW8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/562970:BTUS_RS15340 ^@ http://purl.uniprot.org/uniprot/D5WWD2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS04980 ^@ http://purl.uniprot.org/uniprot/D5WWM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS12105 ^@ http://purl.uniprot.org/uniprot/D5WSQ6 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/562970:BTUS_RS00220 ^@ http://purl.uniprot.org/uniprot/D5WRF6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/562970:BTUS_RS14335 ^@ http://purl.uniprot.org/uniprot/D5WV27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS15895 ^@ http://purl.uniprot.org/uniprot/D5WX25 ^@ Similarity ^@ Belongs to the PemK/MazF family. http://togogenome.org/gene/562970:BTUS_RS02770 ^@ http://purl.uniprot.org/uniprot/D5WTZ4 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/562970:BTUS_RS00635 ^@ http://purl.uniprot.org/uniprot/D5WRN6 ^@ Similarity ^@ Belongs to the CtsR family. http://togogenome.org/gene/562970:BTUS_RS00840 ^@ http://purl.uniprot.org/uniprot/D5WS54 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/562970:BTUS_RS10300 ^@ http://purl.uniprot.org/uniprot/D5WQX5 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/562970:BTUS_RS10520 ^@ http://purl.uniprot.org/uniprot/D5WR45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/562970:BTUS_RS05045 ^@ http://purl.uniprot.org/uniprot/D5WWN8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS06915 ^@ http://purl.uniprot.org/uniprot/D5WY44 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.|||Membrane http://togogenome.org/gene/562970:BTUS_RS07385 ^@ http://purl.uniprot.org/uniprot/D5WPD8 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/562970:BTUS_RS00955 ^@ http://purl.uniprot.org/uniprot/D5WS77 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS16265 ^@ http://purl.uniprot.org/uniprot/D5WX98 ^@ Activity Regulation|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer. http://togogenome.org/gene/562970:BTUS_RS04945 ^@ http://purl.uniprot.org/uniprot/D5WW88 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/562970:BTUS_RS02465 ^@ http://purl.uniprot.org/uniprot/D5WTT6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/562970:BTUS_RS03950 ^@ http://purl.uniprot.org/uniprot/D5WVD1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/562970:BTUS_RS00935 ^@ http://purl.uniprot.org/uniprot/D5WS73 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/562970:BTUS_RS01210 ^@ http://purl.uniprot.org/uniprot/D5WSD0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS16020 ^@ http://purl.uniprot.org/uniprot/D5WX50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS06890 ^@ http://purl.uniprot.org/uniprot/D5WY40 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).|||Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3). http://togogenome.org/gene/562970:BTUS_RS04665 ^@ http://purl.uniprot.org/uniprot/D5WW37 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS10780 ^@ http://purl.uniprot.org/uniprot/D5WR90 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/562970:BTUS_RS07475 ^@ http://purl.uniprot.org/uniprot/D5WPF6 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/562970:BTUS_RS08540 ^@ http://purl.uniprot.org/uniprot/D5WQ13 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/562970:BTUS_RS11560 ^@ http://purl.uniprot.org/uniprot/D5WS17 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/562970:BTUS_RS02200 ^@ http://purl.uniprot.org/uniprot/D5WT99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS09245 ^@ http://purl.uniprot.org/uniprot/D5WQE1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/562970:BTUS_RS15930 ^@ http://purl.uniprot.org/uniprot/D5WX31 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/562970:BTUS_RS06705 ^@ http://purl.uniprot.org/uniprot/D5WY10 ^@ Subunit ^@ Homotetramer. http://togogenome.org/gene/562970:BTUS_RS12820 ^@ http://purl.uniprot.org/uniprot/D5WTH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS04360 ^@ http://purl.uniprot.org/uniprot/D5WVY3 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/562970:BTUS_RS09970 ^@ http://purl.uniprot.org/uniprot/D5WQR5 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/562970:BTUS_RS14400 ^@ http://purl.uniprot.org/uniprot/D5WV40 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS13640 ^@ http://purl.uniprot.org/uniprot/D5WUC1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/562970:BTUS_RS14035 ^@ http://purl.uniprot.org/uniprot/D5WUX7 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/562970:BTUS_RS15640 ^@ http://purl.uniprot.org/uniprot/D5WWJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS10990 ^@ http://purl.uniprot.org/uniprot/D5WRD2 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/562970:BTUS_RS04735 ^@ http://purl.uniprot.org/uniprot/D5WW48 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS10795 ^@ http://purl.uniprot.org/uniprot/D5WR93 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/562970:BTUS_RS15925 ^@ http://purl.uniprot.org/uniprot/D5WX30 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/562970:BTUS_RS11895 ^@ http://purl.uniprot.org/uniprot/D5WSL5 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/562970:BTUS_RS04965 ^@ http://purl.uniprot.org/uniprot/D5WW92 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS06325 ^@ http://purl.uniprot.org/uniprot/D5WXT9 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/562970:BTUS_RS13315 ^@ http://purl.uniprot.org/uniprot/D5WU59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS09065 ^@ http://purl.uniprot.org/uniprot/D5WQA5 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/562970:BTUS_RS10265 ^@ http://purl.uniprot.org/uniprot/D5WQW9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS03325 ^@ http://purl.uniprot.org/uniprot/D5WUM9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS03055 ^@ http://purl.uniprot.org/uniprot/D5WUI1 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/562970:BTUS_RS15610 ^@ http://purl.uniprot.org/uniprot/D5WWI6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/562970:BTUS_RS10915 ^@ http://purl.uniprot.org/uniprot/D5WRB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS04865 ^@ http://purl.uniprot.org/uniprot/D5WW71 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/562970:BTUS_RS06095 ^@ http://purl.uniprot.org/uniprot/D5WXN1 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/562970:BTUS_RS06605 ^@ http://purl.uniprot.org/uniprot/D5WXZ1 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/562970:BTUS_RS13030 ^@ http://purl.uniprot.org/uniprot/D5WTL9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS07680 ^@ http://purl.uniprot.org/uniprot/D5WPJ6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/562970:BTUS_RS09450 ^@ http://purl.uniprot.org/uniprot/D5WQH9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS14905 ^@ http://purl.uniprot.org/uniprot/D5WVS1 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/562970:BTUS_RS07200 ^@ http://purl.uniprot.org/uniprot/D5WPA0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS16225 ^@ http://purl.uniprot.org/uniprot/D5WX90 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/562970:BTUS_RS07375 ^@ http://purl.uniprot.org/uniprot/D5WPD6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/562970:BTUS_RS02435 ^@ http://purl.uniprot.org/uniprot/D5WTT0 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/562970:BTUS_RS06690 ^@ http://purl.uniprot.org/uniprot/D5WY07 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.|||Cytoplasm|||Heterotetramer of 2 PyrK and 2 PyrD type B subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS16325 ^@ http://purl.uniprot.org/uniprot/D5WXA9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/562970:BTUS_RS04115 ^@ http://purl.uniprot.org/uniprot/D5WVG0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/562970:BTUS_RS00875 ^@ http://purl.uniprot.org/uniprot/D5WS61 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/562970:BTUS_RS12030 ^@ http://purl.uniprot.org/uniprot/D5WSP1 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/562970:BTUS_RS02130 ^@ http://purl.uniprot.org/uniprot/D5WT85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS06175 ^@ http://purl.uniprot.org/uniprot/D5WXP7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS09310 ^@ http://purl.uniprot.org/uniprot/D5WQF4 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/562970:BTUS_RS02775 ^@ http://purl.uniprot.org/uniprot/D5WTZ5 ^@ Function|||Similarity ^@ Belongs to the cyanase family.|||Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. http://togogenome.org/gene/562970:BTUS_RS16135 ^@ http://purl.uniprot.org/uniprot/D5WX73 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/562970:BTUS_RS14110 ^@ http://purl.uniprot.org/uniprot/D5WUZ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/562970:BTUS_RS02210 ^@ http://purl.uniprot.org/uniprot/D5WTN5 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/562970:BTUS_RS00775 ^@ http://purl.uniprot.org/uniprot/D5WRR5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/562970:BTUS_RS08150 ^@ http://purl.uniprot.org/uniprot/D5WPT8 ^@ Similarity ^@ Belongs to the CbxX/CfxQ family. http://togogenome.org/gene/562970:BTUS_RS00820 ^@ http://purl.uniprot.org/uniprot/D5WRS4 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/562970:BTUS_RS10070 ^@ http://purl.uniprot.org/uniprot/D5WQT1 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/562970:BTUS_RS09620 ^@ http://purl.uniprot.org/uniprot/D5WQK5 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/562970:BTUS_RS12190 ^@ http://purl.uniprot.org/uniprot/D5WSS4 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/562970:BTUS_RS15260 ^@ http://purl.uniprot.org/uniprot/D5WWB8 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS03830 ^@ http://purl.uniprot.org/uniprot/D5WVA8 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/562970:BTUS_RS13215 ^@ http://purl.uniprot.org/uniprot/D5WU40 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/562970:BTUS_RS08075 ^@ http://purl.uniprot.org/uniprot/D5WPS4 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/562970:BTUS_RS03720 ^@ http://purl.uniprot.org/uniprot/D5WV87 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS02850 ^@ http://purl.uniprot.org/uniprot/D5WU10 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/562970:BTUS_RS13160 ^@ http://purl.uniprot.org/uniprot/D5WU28 ^@ Similarity ^@ Belongs to the EfeM/EfeO family. http://togogenome.org/gene/562970:BTUS_RS02865 ^@ http://purl.uniprot.org/uniprot/D5WU13 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS03315 ^@ http://purl.uniprot.org/uniprot/D5WUM7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ALAD family.|||Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.|||Homooctamer. http://togogenome.org/gene/562970:BTUS_RS16140 ^@ http://purl.uniprot.org/uniprot/D5WX74 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/562970:BTUS_RS15050 ^@ http://purl.uniprot.org/uniprot/D5WVU9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS03560 ^@ http://purl.uniprot.org/uniprot/D5WUS4 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/562970:BTUS_RS13020 ^@ http://purl.uniprot.org/uniprot/D5WTL7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS14820 ^@ http://purl.uniprot.org/uniprot/D5WVQ7 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/562970:BTUS_RS05575 ^@ http://purl.uniprot.org/uniprot/D5WWZ6 ^@ Similarity ^@ Belongs to the UPF0297 family. http://togogenome.org/gene/562970:BTUS_RS05185 ^@ http://purl.uniprot.org/uniprot/D5WWR8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase. http://togogenome.org/gene/562970:BTUS_RS16425 ^@ http://purl.uniprot.org/uniprot/D5WXC4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/562970:BTUS_RS10760 ^@ http://purl.uniprot.org/uniprot/D5WR86 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/562970:BTUS_RS06525 ^@ http://purl.uniprot.org/uniprot/D5WXX5 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS15475 ^@ http://purl.uniprot.org/uniprot/D5WWF8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/562970:BTUS_RS02935 ^@ http://purl.uniprot.org/uniprot/D5WUF6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/562970:BTUS_RS02260 ^@ http://purl.uniprot.org/uniprot/D5WTP5 ^@ Caution|||Function|||Similarity ^@ Belongs to the NrdR family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/562970:BTUS_RS05830 ^@ http://purl.uniprot.org/uniprot/D5WXH9 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/562970:BTUS_RS09205 ^@ http://purl.uniprot.org/uniprot/D5WQD3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/562970:BTUS_RS04740 ^@ http://purl.uniprot.org/uniprot/D5WW49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS15555 ^@ http://purl.uniprot.org/uniprot/D5WWH5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/562970:BTUS_RS14975 ^@ http://purl.uniprot.org/uniprot/D5WVT5 ^@ Similarity ^@ Belongs to the alpha/beta-type SASP family. http://togogenome.org/gene/562970:BTUS_RS00900 ^@ http://purl.uniprot.org/uniprot/D5WS66 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/562970:BTUS_RS08265 ^@ http://purl.uniprot.org/uniprot/D5WPV8 ^@ Similarity ^@ Belongs to the NifZ family. http://togogenome.org/gene/562970:BTUS_RS02380 ^@ http://purl.uniprot.org/uniprot/D5WTR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/562970:BTUS_RS16505 ^@ http://purl.uniprot.org/uniprot/D5WXS2 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/562970:BTUS_RS12115 ^@ http://purl.uniprot.org/uniprot/D5WSQ9 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/562970:BTUS_RS14415 ^@ http://purl.uniprot.org/uniprot/D5WV43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/562970:BTUS_RS08515 ^@ http://purl.uniprot.org/uniprot/D5WQ08 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/562970:BTUS_RS02095 ^@ http://purl.uniprot.org/uniprot/D5WT79 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/562970:BTUS_RS10145 ^@ http://purl.uniprot.org/uniprot/D5WQU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS16240 ^@ http://purl.uniprot.org/uniprot/D5WX93 ^@ Function|||Similarity ^@ Belongs to the transferase hexapeptide repeat family. DapH subfamily.|||Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. http://togogenome.org/gene/562970:BTUS_RS04145 ^@ http://purl.uniprot.org/uniprot/D5WVG6 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/562970:BTUS_RS08285 ^@ http://purl.uniprot.org/uniprot/D5WPW4 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/562970:BTUS_RS10315 ^@ http://purl.uniprot.org/uniprot/D5WQX8 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/562970:BTUS_RS12500 ^@ http://purl.uniprot.org/uniprot/D5WTB6 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/562970:BTUS_RS10925 ^@ http://purl.uniprot.org/uniprot/D5WRB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS06015 ^@ http://purl.uniprot.org/uniprot/D5WXL5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/562970:BTUS_RS03115 ^@ http://purl.uniprot.org/uniprot/D5WUI8 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/562970:BTUS_RS11645 ^@ http://purl.uniprot.org/uniprot/D5WS34 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. http://togogenome.org/gene/562970:BTUS_RS10390 ^@ http://purl.uniprot.org/uniprot/D5WR21 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS04650 ^@ http://purl.uniprot.org/uniprot/D5WW34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS05465 ^@ http://purl.uniprot.org/uniprot/D5WWX4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS01195 ^@ http://purl.uniprot.org/uniprot/D5WSC7 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/562970:BTUS_RS09845 ^@ http://purl.uniprot.org/uniprot/D5WQN9 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/562970:BTUS_RS09055 ^@ http://purl.uniprot.org/uniprot/D5WQA3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS03435 ^@ http://purl.uniprot.org/uniprot/D5WUQ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/562970:BTUS_RS05295 ^@ http://purl.uniprot.org/uniprot/D5WWU0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/562970:BTUS_RS05230 ^@ http://purl.uniprot.org/uniprot/D5WWS8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS06930 ^@ http://purl.uniprot.org/uniprot/D5WY47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS13170 ^@ http://purl.uniprot.org/uniprot/D5WU30 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/562970:BTUS_RS02645 ^@ http://purl.uniprot.org/uniprot/D5WTX3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/562970:BTUS_RS00895 ^@ http://purl.uniprot.org/uniprot/D5WS65 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/562970:BTUS_RS15745 ^@ http://purl.uniprot.org/uniprot/D5WWL3 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/562970:BTUS_RS13310 ^@ http://purl.uniprot.org/uniprot/D5WU58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS02895 ^@ http://purl.uniprot.org/uniprot/D5WUE9 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/562970:BTUS_RS04940 ^@ http://purl.uniprot.org/uniprot/D5WW87 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/562970:BTUS_RS12060 ^@ http://purl.uniprot.org/uniprot/D5WSP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS05560 ^@ http://purl.uniprot.org/uniprot/D5WWZ3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS02065 ^@ http://purl.uniprot.org/uniprot/D5WT73 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/562970:BTUS_RS09135 ^@ http://purl.uniprot.org/uniprot/D5WQB9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/562970:BTUS_RS02205 ^@ http://purl.uniprot.org/uniprot/D5WTN4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS18575 ^@ http://purl.uniprot.org/uniprot/D5WWE0 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/562970:BTUS_RS10910 ^@ http://purl.uniprot.org/uniprot/D5WRB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/562970:BTUS_RS02330 ^@ http://purl.uniprot.org/uniprot/D5WTQ9 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/562970:BTUS_RS14085 ^@ http://purl.uniprot.org/uniprot/D5WUY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/562970:BTUS_RS00525 ^@ http://purl.uniprot.org/uniprot/D5WRL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS02020 ^@ http://purl.uniprot.org/uniprot/D5WT64 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/562970:BTUS_RS13100 ^@ http://purl.uniprot.org/uniprot/D5WTN3 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/562970:BTUS_RS03350 ^@ http://purl.uniprot.org/uniprot/D5WUN4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/562970:BTUS_RS11055 ^@ http://purl.uniprot.org/uniprot/D5WRE6 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS07380 ^@ http://purl.uniprot.org/uniprot/D5WPD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/562970:BTUS_RS06310 ^@ http://purl.uniprot.org/uniprot/D5WXT6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS07690 ^@ http://purl.uniprot.org/uniprot/D5WPJ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/562970:BTUS_RS06195 ^@ http://purl.uniprot.org/uniprot/D5WXQ1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS03130 ^@ http://purl.uniprot.org/uniprot/D5WUJ1 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/562970:BTUS_RS00790 ^@ http://purl.uniprot.org/uniprot/D5WRR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/562970:BTUS_RS17005 ^@ http://purl.uniprot.org/uniprot/D5WTD2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS00690 ^@ http://purl.uniprot.org/uniprot/D5WRP7 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/562970:BTUS_RS00770 ^@ http://purl.uniprot.org/uniprot/D5WRR4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family. http://togogenome.org/gene/562970:BTUS_RS16460 ^@ http://purl.uniprot.org/uniprot/D5WXD1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/562970:BTUS_RS02345 ^@ http://purl.uniprot.org/uniprot/D5WTR2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS07515 ^@ http://purl.uniprot.org/uniprot/D5WPG4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/562970:BTUS_RS18260 ^@ http://purl.uniprot.org/uniprot/D5WRL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS07595 ^@ http://purl.uniprot.org/uniprot/D5WPI0 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS07125 ^@ http://purl.uniprot.org/uniprot/D5WP83 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/562970:BTUS_RS06185 ^@ http://purl.uniprot.org/uniprot/D5WXP9 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/562970:BTUS_RS06220 ^@ http://purl.uniprot.org/uniprot/D5WXQ6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/562970:BTUS_RS04455 ^@ http://purl.uniprot.org/uniprot/D5WVZ6 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/562970:BTUS_RS00945 ^@ http://purl.uniprot.org/uniprot/D5WS75 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/562970:BTUS_RS11145 ^@ http://purl.uniprot.org/uniprot/D5WRU6 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/562970:BTUS_RS15080 ^@ http://purl.uniprot.org/uniprot/D5WVV4 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/562970:BTUS_RS07960 ^@ http://purl.uniprot.org/uniprot/D5WPQ1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS09175 ^@ http://purl.uniprot.org/uniprot/D5WQC7 ^@ Function|||Similarity ^@ Belongs to the anti-sigma-factor antagonist family.|||In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition. http://togogenome.org/gene/562970:BTUS_RS11870 ^@ http://purl.uniprot.org/uniprot/D5WSL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS04080 ^@ http://purl.uniprot.org/uniprot/D5WVF3 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/562970:BTUS_RS07620 ^@ http://purl.uniprot.org/uniprot/D5WPI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS13705 ^@ http://purl.uniprot.org/uniprot/D5WUD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS07835 ^@ http://purl.uniprot.org/uniprot/D5WPM5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/562970:BTUS_RS04500 ^@ http://purl.uniprot.org/uniprot/D5WW06 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/562970:BTUS_RS12050 ^@ http://purl.uniprot.org/uniprot/D5WSP5 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/562970:BTUS_RS07370 ^@ http://purl.uniprot.org/uniprot/D5WPD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers). http://togogenome.org/gene/562970:BTUS_RS10140 ^@ http://purl.uniprot.org/uniprot/D5WQU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS00785 ^@ http://purl.uniprot.org/uniprot/D5WRR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS01285 ^@ http://purl.uniprot.org/uniprot/D5WSE3 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/562970:BTUS_RS16045 ^@ http://purl.uniprot.org/uniprot/D5WX55 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/562970:BTUS_RS07425 ^@ http://purl.uniprot.org/uniprot/D5WPE6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/562970:BTUS_RS11020 ^@ http://purl.uniprot.org/uniprot/D5WRD8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreF family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/562970:BTUS_RS09865 ^@ http://purl.uniprot.org/uniprot/D5WQP3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/562970:BTUS_RS15495 ^@ http://purl.uniprot.org/uniprot/D5WWG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. EmrB family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS14580 ^@ http://purl.uniprot.org/uniprot/D5WVK6 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/562970:BTUS_RS07855 ^@ http://purl.uniprot.org/uniprot/D5WPM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS12665 ^@ http://purl.uniprot.org/uniprot/D5WTE9 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/562970:BTUS_RS00225 ^@ http://purl.uniprot.org/uniprot/D5WRF7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/562970:BTUS_RS11060 ^@ http://purl.uniprot.org/uniprot/D5WRE7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. http://togogenome.org/gene/562970:BTUS_RS08740 ^@ http://purl.uniprot.org/uniprot/D5WQ49 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS08140 ^@ http://purl.uniprot.org/uniprot/D5WPT6 ^@ Similarity ^@ Belongs to the homogentisate dioxygenase family. http://togogenome.org/gene/562970:BTUS_RS10060 ^@ http://purl.uniprot.org/uniprot/D5WQS9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS14355 ^@ http://purl.uniprot.org/uniprot/D5WV31 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/562970:BTUS_RS14895 ^@ http://purl.uniprot.org/uniprot/D5WVR9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/562970:BTUS_RS10445 ^@ http://purl.uniprot.org/uniprot/D5WR32 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/562970:BTUS_RS07990 ^@ http://purl.uniprot.org/uniprot/D5WPQ7 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/562970:BTUS_RS00865 ^@ http://purl.uniprot.org/uniprot/D5WS59 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/562970:BTUS_RS14460 ^@ http://purl.uniprot.org/uniprot/D5WV52 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/562970:BTUS_RS11335 ^@ http://purl.uniprot.org/uniprot/D5WRX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS07825 ^@ http://purl.uniprot.org/uniprot/D5WPM3 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/562970:BTUS_RS03125 ^@ http://purl.uniprot.org/uniprot/D5WUJ0 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS06580 ^@ http://purl.uniprot.org/uniprot/D5WXY6 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/562970:BTUS_RS11820 ^@ http://purl.uniprot.org/uniprot/D5WSK0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/562970:BTUS_RS07150 ^@ http://purl.uniprot.org/uniprot/D5WP89 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/562970:BTUS_RS08350 ^@ http://purl.uniprot.org/uniprot/D5WPX6 ^@ Similarity ^@ Belongs to the AAA ATPase family.|||In the C-terminal section; belongs to the peptidase M41 family. http://togogenome.org/gene/562970:BTUS_RS06935 ^@ http://purl.uniprot.org/uniprot/D5WY48 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/562970:BTUS_RS16295 ^@ http://purl.uniprot.org/uniprot/D5WXA3 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS10305 ^@ http://purl.uniprot.org/uniprot/D5WQX6 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/562970:BTUS_RS14885 ^@ http://purl.uniprot.org/uniprot/D5WVR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/562970:BTUS_RS01185 ^@ http://purl.uniprot.org/uniprot/D5WSC4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/562970:BTUS_RS07875 ^@ http://purl.uniprot.org/uniprot/D5WPN4 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/562970:BTUS_RS06675 ^@ http://purl.uniprot.org/uniprot/D5WY04 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS02060 ^@ http://purl.uniprot.org/uniprot/D5WT72 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/562970:BTUS_RS15150 ^@ http://purl.uniprot.org/uniprot/D5WW96 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/562970:BTUS_RS07155 ^@ http://purl.uniprot.org/uniprot/D5WP90 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS12845 ^@ http://purl.uniprot.org/uniprot/D5WTI2 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS04635 ^@ http://purl.uniprot.org/uniprot/D5WW31 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/562970:BTUS_RS06655 ^@ http://purl.uniprot.org/uniprot/D5WY00 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/562970:BTUS_RS09685 ^@ http://purl.uniprot.org/uniprot/D5WQL8 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/562970:BTUS_RS05485 ^@ http://purl.uniprot.org/uniprot/D5WWX8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS05580 ^@ http://purl.uniprot.org/uniprot/D5WWZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS01565 ^@ http://purl.uniprot.org/uniprot/D5WSX9 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/562970:BTUS_RS07420 ^@ http://purl.uniprot.org/uniprot/D5WPE5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/562970:BTUS_RS00020 ^@ http://purl.uniprot.org/uniprot/D5WQZ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/562970:BTUS_RS17075 ^@ http://purl.uniprot.org/uniprot/D5WV08 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS07935 ^@ http://purl.uniprot.org/uniprot/D5WPP6 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/562970:BTUS_RS16115 ^@ http://purl.uniprot.org/uniprot/D5WX69 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/562970:BTUS_RS07585 ^@ http://purl.uniprot.org/uniprot/D5WPH8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/562970:BTUS_RS06510 ^@ http://purl.uniprot.org/uniprot/D5WXX2 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/562970:BTUS_RS07160 ^@ http://purl.uniprot.org/uniprot/D5WP91 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/562970:BTUS_RS01215 ^@ http://purl.uniprot.org/uniprot/D5WSD1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane|||Part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/562970:BTUS_RS13840 ^@ http://purl.uniprot.org/uniprot/D5WUT8 ^@ PTM ^@ Binds 1 heme c group covalently per subunit. http://togogenome.org/gene/562970:BTUS_RS06590 ^@ http://purl.uniprot.org/uniprot/D5WXY8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/562970:BTUS_RS05555 ^@ http://purl.uniprot.org/uniprot/D5WWZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS00370 ^@ http://purl.uniprot.org/uniprot/D5WRI6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS11510 ^@ http://purl.uniprot.org/uniprot/D5WS07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. EmrB family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS08615 ^@ http://purl.uniprot.org/uniprot/D5WQ29 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/562970:BTUS_RS07415 ^@ http://purl.uniprot.org/uniprot/D5WPE4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CodY family.|||Cytoplasm|||DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion. http://togogenome.org/gene/562970:BTUS_RS00825 ^@ http://purl.uniprot.org/uniprot/D5WRS5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/562970:BTUS_RS04515 ^@ http://purl.uniprot.org/uniprot/D5WW09 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/562970:BTUS_RS03390 ^@ http://purl.uniprot.org/uniprot/D5WUP2 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/562970:BTUS_RS08410 ^@ http://purl.uniprot.org/uniprot/D5WPY7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/562970:BTUS_RS02890 ^@ http://purl.uniprot.org/uniprot/D5WUE8 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/562970:BTUS_RS03510 ^@ http://purl.uniprot.org/uniprot/D5WUR4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/562970:BTUS_RS09965 ^@ http://purl.uniprot.org/uniprot/D5WQR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS13150 ^@ http://purl.uniprot.org/uniprot/D5WU26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS00530 ^@ http://purl.uniprot.org/uniprot/D5WRL7 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/562970:BTUS_RS00550 ^@ http://purl.uniprot.org/uniprot/D5WRM1 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/562970:BTUS_RS04105 ^@ http://purl.uniprot.org/uniprot/D5WVF8 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/562970:BTUS_RS11250 ^@ http://purl.uniprot.org/uniprot/D5WRW2 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/562970:BTUS_RS08110 ^@ http://purl.uniprot.org/uniprot/D5WPT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS06315 ^@ http://purl.uniprot.org/uniprot/D5WXT7 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/562970:BTUS_RS18615 ^@ http://purl.uniprot.org/uniprot/D5WQ58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS00410 ^@ http://purl.uniprot.org/uniprot/D5WRJ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS12125 ^@ http://purl.uniprot.org/uniprot/D5WSR1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS09130 ^@ http://purl.uniprot.org/uniprot/D5WQB8 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/562970:BTUS_RS13255 ^@ http://purl.uniprot.org/uniprot/D5WU47 ^@ Similarity ^@ Belongs to the truncated hemoglobin family. Group II subfamily. http://togogenome.org/gene/562970:BTUS_RS07490 ^@ http://purl.uniprot.org/uniprot/D5WPF9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS03690 ^@ http://purl.uniprot.org/uniprot/D5WV81 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/562970:BTUS_RS05515 ^@ http://purl.uniprot.org/uniprot/D5WWY4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/562970:BTUS_RS09190 ^@ http://purl.uniprot.org/uniprot/D5WQD0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/562970:BTUS_RS07080 ^@ http://purl.uniprot.org/uniprot/D5WP75 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/562970:BTUS_RS05175 ^@ http://purl.uniprot.org/uniprot/D5WWR6 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/562970:BTUS_RS07625 ^@ http://purl.uniprot.org/uniprot/D5WPI6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/562970:BTUS_RS15265 ^@ http://purl.uniprot.org/uniprot/D5WWB9 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/562970:BTUS_RS13045 ^@ http://purl.uniprot.org/uniprot/D5WTM2 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/562970:BTUS_RS08770 ^@ http://purl.uniprot.org/uniprot/D5WQ55 ^@ Function|||Subcellular Location Annotation ^@ ATPase. Has a role at an early stage in the morphogenesis of the spore coat.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS12270 ^@ http://purl.uniprot.org/uniprot/D5WSU0 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/562970:BTUS_RS12655 ^@ http://purl.uniprot.org/uniprot/D5WTE7 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/562970:BTUS_RS07050 ^@ http://purl.uniprot.org/uniprot/D5WP69 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/562970:BTUS_RS16090 ^@ http://purl.uniprot.org/uniprot/D5WX64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/562970:BTUS_RS07685 ^@ http://purl.uniprot.org/uniprot/D5WPJ7 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/562970:BTUS_RS18315 ^@ http://purl.uniprot.org/uniprot/D5WVC5 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/562970:BTUS_RS01080 ^@ http://purl.uniprot.org/uniprot/D5WSA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/562970:BTUS_RS04525 ^@ http://purl.uniprot.org/uniprot/D5WW11 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS08530 ^@ http://purl.uniprot.org/uniprot/D5WQ11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/562970:BTUS_RS10490 ^@ http://purl.uniprot.org/uniprot/D5WR39 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/562970:BTUS_RS01180 ^@ http://purl.uniprot.org/uniprot/D5WSC3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/562970:BTUS_RS01005 ^@ http://purl.uniprot.org/uniprot/D5WS87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS07985 ^@ http://purl.uniprot.org/uniprot/D5WPQ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/562970:BTUS_RS13955 ^@ http://purl.uniprot.org/uniprot/D5WUW0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer.|||Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). http://togogenome.org/gene/562970:BTUS_RS06400 ^@ http://purl.uniprot.org/uniprot/D5WXV1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS03195 ^@ http://purl.uniprot.org/uniprot/D5WUK5 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/562970:BTUS_RS08725 ^@ http://purl.uniprot.org/uniprot/D5WQ46 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnC family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/562970:BTUS_RS03630 ^@ http://purl.uniprot.org/uniprot/D5WV68 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/562970:BTUS_RS00155 ^@ http://purl.uniprot.org/uniprot/D5WR15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS01465 ^@ http://purl.uniprot.org/uniprot/D5WSH9 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/562970:BTUS_RS05055 ^@ http://purl.uniprot.org/uniprot/D5WWP0 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/562970:BTUS_RS03405 ^@ http://purl.uniprot.org/uniprot/D5WUP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS08495 ^@ http://purl.uniprot.org/uniprot/D5WQ04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS01025 ^@ http://purl.uniprot.org/uniprot/D5WS91 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/562970:BTUS_RS16215 ^@ http://purl.uniprot.org/uniprot/D5WX88 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/562970:BTUS_RS07010 ^@ http://purl.uniprot.org/uniprot/D5WP61 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS12575 ^@ http://purl.uniprot.org/uniprot/D5WTD1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS13015 ^@ http://purl.uniprot.org/uniprot/D5WTL6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS14365 ^@ http://purl.uniprot.org/uniprot/D5WV33 ^@ Similarity ^@ Belongs to the phosphoribulokinase family. http://togogenome.org/gene/562970:BTUS_RS16125 ^@ http://purl.uniprot.org/uniprot/D5WX71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS13475 ^@ http://purl.uniprot.org/uniprot/D5WU90 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS05730 ^@ http://purl.uniprot.org/uniprot/D5WXF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS02560 ^@ http://purl.uniprot.org/uniprot/D5WTV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS11240 ^@ http://purl.uniprot.org/uniprot/D5WRW1 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/562970:BTUS_RS15950 ^@ http://purl.uniprot.org/uniprot/D5WX35 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/562970:BTUS_RS14090 ^@ http://purl.uniprot.org/uniprot/D5WUY7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/562970:BTUS_RS12410 ^@ http://purl.uniprot.org/uniprot/D5WSW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS15735 ^@ http://purl.uniprot.org/uniprot/D5WWL1 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/562970:BTUS_RS00235 ^@ http://purl.uniprot.org/uniprot/D5WRF9 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/562970:BTUS_RS09640 ^@ http://purl.uniprot.org/uniprot/D5WQK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS07845 ^@ http://purl.uniprot.org/uniprot/D5WPM7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS01170 ^@ http://purl.uniprot.org/uniprot/D5WSC1 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/562970:BTUS_RS09650 ^@ http://purl.uniprot.org/uniprot/D5WQL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS11175 ^@ http://purl.uniprot.org/uniprot/D5WRV2 ^@ Similarity ^@ Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family. http://togogenome.org/gene/562970:BTUS_RS16320 ^@ http://purl.uniprot.org/uniprot/D5WXA8 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/562970:BTUS_RS00280 ^@ http://purl.uniprot.org/uniprot/D5WRG8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS10160 ^@ http://purl.uniprot.org/uniprot/D5WQU8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS14370 ^@ http://purl.uniprot.org/uniprot/D5WV34 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS01580 ^@ http://purl.uniprot.org/uniprot/D5WSY2 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/562970:BTUS_RS15485 ^@ http://purl.uniprot.org/uniprot/D5WWG0 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/562970:BTUS_RS00205 ^@ http://purl.uniprot.org/uniprot/D5WRF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/562970:BTUS_RS14285 ^@ http://purl.uniprot.org/uniprot/D5WV18 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS10025 ^@ http://purl.uniprot.org/uniprot/D5WQS4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/562970:BTUS_RS15715 ^@ http://purl.uniprot.org/uniprot/D5WWK7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS08400 ^@ http://purl.uniprot.org/uniprot/D5WPY5 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/562970:BTUS_RS09955 ^@ http://purl.uniprot.org/uniprot/D5WQR2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M32 family.|||Binds 1 zinc ion per subunit.|||Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. http://togogenome.org/gene/562970:BTUS_RS11400 ^@ http://purl.uniprot.org/uniprot/D5WRZ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS11465 ^@ http://purl.uniprot.org/uniprot/D5WS04 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS13285 ^@ http://purl.uniprot.org/uniprot/D5WU53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS12770 ^@ http://purl.uniprot.org/uniprot/D5WTG9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/562970:BTUS_RS06455 ^@ http://purl.uniprot.org/uniprot/D5WXW1 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/562970:BTUS_RS17060 ^@ http://purl.uniprot.org/uniprot/D5WUZ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/562970:BTUS_RS04100 ^@ http://purl.uniprot.org/uniprot/D5WVF7 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/562970:BTUS_RS14340 ^@ http://purl.uniprot.org/uniprot/D5WV28 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/562970:BTUS_RS11950 ^@ http://purl.uniprot.org/uniprot/D5WSM7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/562970:BTUS_RS15455 ^@ http://purl.uniprot.org/uniprot/D5WWF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS02045 ^@ http://purl.uniprot.org/uniprot/D5WT69 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/562970:BTUS_RS16145 ^@ http://purl.uniprot.org/uniprot/D5WX75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS09240 ^@ http://purl.uniprot.org/uniprot/D5WQE0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/562970:BTUS_RS03135 ^@ http://purl.uniprot.org/uniprot/D5WUJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS07630 ^@ http://purl.uniprot.org/uniprot/D5WPI7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS00680 ^@ http://purl.uniprot.org/uniprot/D5WRP5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS05920 ^@ http://purl.uniprot.org/uniprot/D5WXJ6 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/562970:BTUS_RS16025 ^@ http://purl.uniprot.org/uniprot/D5WX51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.|||Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/562970:BTUS_RS07520 ^@ http://purl.uniprot.org/uniprot/D5WPG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliR/MopE/SpaR family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS07210 ^@ http://purl.uniprot.org/uniprot/D5WPA2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/562970:BTUS_RS09020 ^@ http://purl.uniprot.org/uniprot/D5WQ96 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/562970:BTUS_RS16120 ^@ http://purl.uniprot.org/uniprot/D5WX70 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/562970:BTUS_RS05820 ^@ http://purl.uniprot.org/uniprot/D5WXH5 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/562970:BTUS_RS00620 ^@ http://purl.uniprot.org/uniprot/D5WRN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS12205 ^@ http://purl.uniprot.org/uniprot/D5WSS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS13050 ^@ http://purl.uniprot.org/uniprot/D5WTM3 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/562970:BTUS_RS06410 ^@ http://purl.uniprot.org/uniprot/D5WXV3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS16075 ^@ http://purl.uniprot.org/uniprot/D5WX61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/562970:BTUS_RS04075 ^@ http://purl.uniprot.org/uniprot/D5WVF2 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/562970:BTUS_RS00670 ^@ http://purl.uniprot.org/uniprot/D5WRP3 ^@ Similarity ^@ Belongs to the ycf81 family. http://togogenome.org/gene/562970:BTUS_RS11945 ^@ http://purl.uniprot.org/uniprot/D5WSM6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/562970:BTUS_RS08855 ^@ http://purl.uniprot.org/uniprot/D5WQ73 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS06360 ^@ http://purl.uniprot.org/uniprot/D5WXU5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS03700 ^@ http://purl.uniprot.org/uniprot/D5WV83 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/562970:BTUS_RS06845 ^@ http://purl.uniprot.org/uniprot/D5WY31 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS09670 ^@ http://purl.uniprot.org/uniprot/D5WQL5 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/562970:BTUS_RS01755 ^@ http://purl.uniprot.org/uniprot/D5WT15 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. http://togogenome.org/gene/562970:BTUS_RS13005 ^@ http://purl.uniprot.org/uniprot/D5WTL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/562970:BTUS_RS07650 ^@ http://purl.uniprot.org/uniprot/D5WPJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/562970:BTUS_RS09170 ^@ http://purl.uniprot.org/uniprot/D5WQC6 ^@ Function|||Similarity ^@ Belongs to the anti-sigma-factor family.|||Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. http://togogenome.org/gene/562970:BTUS_RS14530 ^@ http://purl.uniprot.org/uniprot/D5WVJ7 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. http://togogenome.org/gene/562970:BTUS_RS03940 ^@ http://purl.uniprot.org/uniprot/D5WVC9 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/562970:BTUS_RS07730 ^@ http://purl.uniprot.org/uniprot/D5WPK5 ^@ Similarity ^@ Belongs to the TmoD/XamoD family. http://togogenome.org/gene/562970:BTUS_RS06905 ^@ http://purl.uniprot.org/uniprot/D5WY42 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/562970:BTUS_RS16520 ^@ http://purl.uniprot.org/uniprot/D5WXS5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 535 of 16S rRNA. http://togogenome.org/gene/562970:BTUS_RS06835 ^@ http://purl.uniprot.org/uniprot/D5WY29 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/562970:BTUS_RS04275 ^@ http://purl.uniprot.org/uniprot/D5WVW7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS09230 ^@ http://purl.uniprot.org/uniprot/D5WQD8 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/562970:BTUS_RS01550 ^@ http://purl.uniprot.org/uniprot/D5WSX6 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/562970:BTUS_RS04845 ^@ http://purl.uniprot.org/uniprot/D5WW67 ^@ Similarity ^@ Belongs to the TmoD/XamoD family. http://togogenome.org/gene/562970:BTUS_RS03975 ^@ http://purl.uniprot.org/uniprot/D5WVD6 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/562970:BTUS_RS03555 ^@ http://purl.uniprot.org/uniprot/D5WUS3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/562970:BTUS_RS10895 ^@ http://purl.uniprot.org/uniprot/D5WRB3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS13550 ^@ http://purl.uniprot.org/uniprot/D5WUA3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/562970:BTUS_RS09320 ^@ http://purl.uniprot.org/uniprot/D5WQF6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/562970:BTUS_RS00905 ^@ http://purl.uniprot.org/uniprot/D5WS67 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/562970:BTUS_RS01515 ^@ http://purl.uniprot.org/uniprot/D5WSX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS06300 ^@ http://purl.uniprot.org/uniprot/D5WXT4 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/562970:BTUS_RS00650 ^@ http://purl.uniprot.org/uniprot/D5WRN9 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/562970:BTUS_RS06005 ^@ http://purl.uniprot.org/uniprot/D5WXL3 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/562970:BTUS_RS10310 ^@ http://purl.uniprot.org/uniprot/D5WQX7 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/562970:BTUS_RS15100 ^@ http://purl.uniprot.org/uniprot/D5WVV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS06495 ^@ http://purl.uniprot.org/uniprot/D5WXW9 ^@ Function ^@ May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/562970:BTUS_RS06210 ^@ http://purl.uniprot.org/uniprot/D5WXQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/562970:BTUS_RS16655 ^@ http://purl.uniprot.org/uniprot/D5WVB5 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the octanoyltransferase LipL family.|||Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.|||The reaction proceeds via a thioester-linked acyl-enzyme intermediate. http://togogenome.org/gene/562970:BTUS_RS07610 ^@ http://purl.uniprot.org/uniprot/D5WPI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS03155 ^@ http://purl.uniprot.org/uniprot/D5WUJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS07195 ^@ http://purl.uniprot.org/uniprot/D5WP99 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/562970:BTUS_RS08375 ^@ http://purl.uniprot.org/uniprot/D5WPY2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/562970:BTUS_RS06225 ^@ http://purl.uniprot.org/uniprot/D5WXQ7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS02475 ^@ http://purl.uniprot.org/uniprot/D5WTT8 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/562970:BTUS_RS05790 ^@ http://purl.uniprot.org/uniprot/D5WXG9 ^@ Cofactor|||Similarity ^@ Belongs to the truncated hemoglobin family. Group I subfamily.|||Binds 1 heme group per subunit. http://togogenome.org/gene/562970:BTUS_RS11890 ^@ http://purl.uniprot.org/uniprot/D5WSL4 ^@ Similarity ^@ Belongs to the alpha/beta-type SASP family. http://togogenome.org/gene/562970:BTUS_RS05010 ^@ http://purl.uniprot.org/uniprot/D5WWN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS03085 ^@ http://purl.uniprot.org/uniprot/D5WUI5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS04445 ^@ http://purl.uniprot.org/uniprot/D5WVZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS04810 ^@ http://purl.uniprot.org/uniprot/D5WW62 ^@ Similarity ^@ Belongs to the GppA/Ppx family. http://togogenome.org/gene/562970:BTUS_RS08230 ^@ http://purl.uniprot.org/uniprot/D5WPV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS08370 ^@ http://purl.uniprot.org/uniprot/D5WPY1 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/562970:BTUS_RS00850 ^@ http://purl.uniprot.org/uniprot/D5WS56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/562970:BTUS_RS11605 ^@ http://purl.uniprot.org/uniprot/D5WS26 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS11640 ^@ http://purl.uniprot.org/uniprot/D5WS33 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/562970:BTUS_RS15045 ^@ http://purl.uniprot.org/uniprot/D5WVU8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LPG synthase family.|||Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS01645 ^@ http://purl.uniprot.org/uniprot/D5WSZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Belongs to the CitM (TC 2.A.11) transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS05525 ^@ http://purl.uniprot.org/uniprot/D5WWY6 ^@ Similarity ^@ In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/562970:BTUS_RS03820 ^@ http://purl.uniprot.org/uniprot/D5WVA5 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/562970:BTUS_RS11410 ^@ http://purl.uniprot.org/uniprot/D5WRZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS03595 ^@ http://purl.uniprot.org/uniprot/D5WV61 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/562970:BTUS_RS07890 ^@ http://purl.uniprot.org/uniprot/D5WPN7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/562970:BTUS_RS15460 ^@ http://purl.uniprot.org/uniprot/D5WWF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS03960 ^@ http://purl.uniprot.org/uniprot/D5WVD4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS16080 ^@ http://purl.uniprot.org/uniprot/D5WX62 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/562970:BTUS_RS18715 ^@ http://purl.uniprot.org/uniprot/D5WWC9 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/562970:BTUS_RS10805 ^@ http://purl.uniprot.org/uniprot/D5WR95 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/562970:BTUS_RS11590 ^@ http://purl.uniprot.org/uniprot/D5WS23 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/562970:BTUS_RS07130 ^@ http://purl.uniprot.org/uniprot/D5WP84 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/562970:BTUS_RS10770 ^@ http://purl.uniprot.org/uniprot/D5WR88 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/562970:BTUS_RS05855 ^@ http://purl.uniprot.org/uniprot/D5WXI3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS11215 ^@ http://purl.uniprot.org/uniprot/D5WRV9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS03750 ^@ http://purl.uniprot.org/uniprot/D5WV93 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/562970:BTUS_RS11600 ^@ http://purl.uniprot.org/uniprot/D5WS25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/562970:BTUS_RS03305 ^@ http://purl.uniprot.org/uniprot/D5WUM5 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/562970:BTUS_RS00010 ^@ http://purl.uniprot.org/uniprot/D5WQZ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/562970:BTUS_RS06995 ^@ http://purl.uniprot.org/uniprot/D5WP58 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/562970:BTUS_RS01850 ^@ http://purl.uniprot.org/uniprot/D5WT31 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/562970:BTUS_RS06155 ^@ http://purl.uniprot.org/uniprot/D5WXP3 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/562970:BTUS_RS03160 ^@ http://purl.uniprot.org/uniprot/D5WUJ7 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/562970:BTUS_RS08340 ^@ http://purl.uniprot.org/uniprot/D5WPX4 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/562970:BTUS_RS07745 ^@ http://purl.uniprot.org/uniprot/D5WPK8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS07970 ^@ http://purl.uniprot.org/uniprot/D5WPQ3 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/562970:BTUS_RS04125 ^@ http://purl.uniprot.org/uniprot/D5WVG2 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/562970:BTUS_RS08850 ^@ http://purl.uniprot.org/uniprot/D5WQ72 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/562970:BTUS_RS14765 ^@ http://purl.uniprot.org/uniprot/D5WVP7 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/562970:BTUS_RS06295 ^@ http://purl.uniprot.org/uniprot/D5WXT3 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/562970:BTUS_RS13905 ^@ http://purl.uniprot.org/uniprot/D5WUV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS07265 ^@ http://purl.uniprot.org/uniprot/D5WPB3 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/562970:BTUS_RS08730 ^@ http://purl.uniprot.org/uniprot/D5WQ47 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnA subfamily.|||Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/562970:BTUS_RS04760 ^@ http://purl.uniprot.org/uniprot/D5WW52 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/562970:BTUS_RS14455 ^@ http://purl.uniprot.org/uniprot/D5WV51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS03755 ^@ http://purl.uniprot.org/uniprot/D5WV94 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS10995 ^@ http://purl.uniprot.org/uniprot/D5WRD3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell inner membrane|||Cell membrane|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. http://togogenome.org/gene/562970:BTUS_RS09545 ^@ http://purl.uniprot.org/uniprot/D5WQJ7 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/562970:BTUS_RS09035 ^@ http://purl.uniprot.org/uniprot/D5WQ99 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS07075 ^@ http://purl.uniprot.org/uniprot/D5WP74 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/562970:BTUS_RS00920 ^@ http://purl.uniprot.org/uniprot/D5WS70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/562970:BTUS_RS13110 ^@ http://purl.uniprot.org/uniprot/D5WU19 ^@ Similarity ^@ Belongs to the ThiD family. http://togogenome.org/gene/562970:BTUS_RS03760 ^@ http://purl.uniprot.org/uniprot/D5WV95 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/562970:BTUS_RS18620 ^@ http://purl.uniprot.org/uniprot/D5WQ59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/562970:BTUS_RS12690 ^@ http://purl.uniprot.org/uniprot/D5WTF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/562970:BTUS_RS15490 ^@ http://purl.uniprot.org/uniprot/D5WWG1 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/562970:BTUS_RS02335 ^@ http://purl.uniprot.org/uniprot/D5WTR0 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/562970:BTUS_RS02300 ^@ http://purl.uniprot.org/uniprot/D5WTQ3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/562970:BTUS_RS10260 ^@ http://purl.uniprot.org/uniprot/D5WQW8 ^@ Similarity ^@ Belongs to the TmoD/XamoD family. http://togogenome.org/gene/562970:BTUS_RS14410 ^@ http://purl.uniprot.org/uniprot/D5WV42 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/562970:BTUS_RS00815 ^@ http://purl.uniprot.org/uniprot/D5WRS3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/562970:BTUS_RS01740 ^@ http://purl.uniprot.org/uniprot/D5WT12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS00830 ^@ http://purl.uniprot.org/uniprot/D5WRS6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/562970:BTUS_RS00430 ^@ http://purl.uniprot.org/uniprot/D5WRJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS16255 ^@ http://purl.uniprot.org/uniprot/D5WX96 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/562970:BTUS_RS07280 ^@ http://purl.uniprot.org/uniprot/D5WPB6 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/562970:BTUS_RS03165 ^@ http://purl.uniprot.org/uniprot/D5WUJ8 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/562970:BTUS_RS00380 ^@ http://purl.uniprot.org/uniprot/D5WRI8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/562970:BTUS_RS00615 ^@ http://purl.uniprot.org/uniprot/D5WRN2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS06680 ^@ http://purl.uniprot.org/uniprot/D5WY05 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/562970:BTUS_RS02750 ^@ http://purl.uniprot.org/uniprot/D5WTZ0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/562970:BTUS_RS01545 ^@ http://purl.uniprot.org/uniprot/D5WSX5 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/562970:BTUS_RS01175 ^@ http://purl.uniprot.org/uniprot/D5WSC2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/562970:BTUS_RS03365 ^@ http://purl.uniprot.org/uniprot/D5WUN7 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/562970:BTUS_RS14390 ^@ http://purl.uniprot.org/uniprot/D5WV38 ^@ Similarity ^@ Belongs to the CbxX/CfxQ family. http://togogenome.org/gene/562970:BTUS_RS16440 ^@ http://purl.uniprot.org/uniprot/D5WXC7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/562970:BTUS_RS10000 ^@ http://purl.uniprot.org/uniprot/D5WQS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS12320 ^@ http://purl.uniprot.org/uniprot/D5WSU9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M3B family.|||Binds 1 zinc ion.|||Has oligopeptidase activity and degrades a variety of small bioactive peptides. http://togogenome.org/gene/562970:BTUS_RS13085 ^@ http://purl.uniprot.org/uniprot/D5WTN0 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs.|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/562970:BTUS_RS00885 ^@ http://purl.uniprot.org/uniprot/D5WS63 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/562970:BTUS_RS02115 ^@ http://purl.uniprot.org/uniprot/D5WT82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/562970:BTUS_RS10745 ^@ http://purl.uniprot.org/uniprot/D5WR83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/562970:BTUS_RS14910 ^@ http://purl.uniprot.org/uniprot/D5WVS2 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/562970:BTUS_RS03140 ^@ http://purl.uniprot.org/uniprot/D5WUJ3 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/562970:BTUS_RS07355 ^@ http://purl.uniprot.org/uniprot/D5WPD1 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/562970:BTUS_RS06025 ^@ http://purl.uniprot.org/uniprot/D5WXL7 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/562970:BTUS_RS16315 ^@ http://purl.uniprot.org/uniprot/D5WXA7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/562970:BTUS_RS06435 ^@ http://purl.uniprot.org/uniprot/D5WXV8 ^@ Similarity ^@ Belongs to the ChdC family. Type 1 subfamily. http://togogenome.org/gene/562970:BTUS_RS13635 ^@ http://purl.uniprot.org/uniprot/D5WUC0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/562970:BTUS_RS06870 ^@ http://purl.uniprot.org/uniprot/D5WY36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS17130 ^@ http://purl.uniprot.org/uniprot/D5WVU3 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/562970:BTUS_RS03685 ^@ http://purl.uniprot.org/uniprot/D5WV80 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/562970:BTUS_RS12475 ^@ http://purl.uniprot.org/uniprot/D5WTB1 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/562970:BTUS_RS03915 ^@ http://purl.uniprot.org/uniprot/D5WVC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/562970:BTUS_RS15235 ^@ http://purl.uniprot.org/uniprot/D5WWB3 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/562970:BTUS_RS11565 ^@ http://purl.uniprot.org/uniprot/D5WS18 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/562970:BTUS_RS08325 ^@ http://purl.uniprot.org/uniprot/D5WPX1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/562970:BTUS_RS11190 ^@ http://purl.uniprot.org/uniprot/D5WRV5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS06600 ^@ http://purl.uniprot.org/uniprot/D5WXZ0 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/562970:BTUS_RS06065 ^@ http://purl.uniprot.org/uniprot/D5WXM5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/562970:BTUS_RS08710 ^@ http://purl.uniprot.org/uniprot/D5WQ43 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS07410 ^@ http://purl.uniprot.org/uniprot/D5WPE3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS07110 ^@ http://purl.uniprot.org/uniprot/D5WP81 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/562970:BTUS_RS12090 ^@ http://purl.uniprot.org/uniprot/D5WSQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS15535 ^@ http://purl.uniprot.org/uniprot/D5WWH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS00270 ^@ http://purl.uniprot.org/uniprot/D5WRG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS06350 ^@ http://purl.uniprot.org/uniprot/D5WXU3 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS02715 ^@ http://purl.uniprot.org/uniprot/D5WTY4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS04970 ^@ http://purl.uniprot.org/uniprot/D5WWM4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/562970:BTUS_RS12195 ^@ http://purl.uniprot.org/uniprot/D5WSS5 ^@ Similarity ^@ Belongs to the pyruvate kinase family.|||In the C-terminal section; belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/562970:BTUS_RS06790 ^@ http://purl.uniprot.org/uniprot/D5WY20 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/562970:BTUS_RS11070 ^@ http://purl.uniprot.org/uniprot/D5WRS7 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/562970:BTUS_RS04400 ^@ http://purl.uniprot.org/uniprot/D5WVY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS03260 ^@ http://purl.uniprot.org/uniprot/D5WUL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/562970:BTUS_RS04745 ^@ http://purl.uniprot.org/uniprot/D5WW50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS00760 ^@ http://purl.uniprot.org/uniprot/D5WRR2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/562970:BTUS_RS15945 ^@ http://purl.uniprot.org/uniprot/D5WX34 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/562970:BTUS_RS16035 ^@ http://purl.uniprot.org/uniprot/D5WX53 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/562970:BTUS_RS16250 ^@ http://purl.uniprot.org/uniprot/D5WX95 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/562970:BTUS_RS01355 ^@ http://purl.uniprot.org/uniprot/D5WSF7 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/562970:BTUS_RS10585 ^@ http://purl.uniprot.org/uniprot/D5WR58 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/562970:BTUS_RS02950 ^@ http://purl.uniprot.org/uniprot/D5WUF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/562970:BTUS_RS05810 ^@ http://purl.uniprot.org/uniprot/D5WXH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS01395 ^@ http://purl.uniprot.org/uniprot/D5WSG5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/562970:BTUS_RS07535 ^@ http://purl.uniprot.org/uniprot/D5WPG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Cell membrane|||Membrane|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/562970:BTUS_RS09015 ^@ http://purl.uniprot.org/uniprot/D5WQ95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS02910 ^@ http://purl.uniprot.org/uniprot/D5WUF2 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/562970:BTUS_RS14350 ^@ http://purl.uniprot.org/uniprot/D5WV30 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/562970:BTUS_RS12920 ^@ http://purl.uniprot.org/uniprot/D5WTJ7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS18870 ^@ http://purl.uniprot.org/uniprot/D5WR36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS10885 ^@ http://purl.uniprot.org/uniprot/D5WRB1 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/562970:BTUS_RS06540 ^@ http://purl.uniprot.org/uniprot/D5WXX8 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/562970:BTUS_RS12200 ^@ http://purl.uniprot.org/uniprot/D5WSS6 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS00240 ^@ http://purl.uniprot.org/uniprot/D5WRG0 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/562970:BTUS_RS16880 ^@ http://purl.uniprot.org/uniprot/D5WQE4 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/562970:BTUS_RS03395 ^@ http://purl.uniprot.org/uniprot/D5WUP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/562970:BTUS_RS01015 ^@ http://purl.uniprot.org/uniprot/D5WS89 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/562970:BTUS_RS08170 ^@ http://purl.uniprot.org/uniprot/D5WPU2 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/562970:BTUS_RS12905 ^@ http://purl.uniprot.org/uniprot/D5WTJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS09565 ^@ http://purl.uniprot.org/uniprot/D5WQK0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/562970:BTUS_RS09080 ^@ http://purl.uniprot.org/uniprot/D5WQA8 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/562970:BTUS_RS04135 ^@ http://purl.uniprot.org/uniprot/D5WVG4 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/562970:BTUS_RS03200 ^@ http://purl.uniprot.org/uniprot/D5WUK6 ^@ Similarity ^@ Belongs to the UPF0166 family. http://togogenome.org/gene/562970:BTUS_RS09285 ^@ http://purl.uniprot.org/uniprot/D5WQE9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS01950 ^@ http://purl.uniprot.org/uniprot/D5WT53 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/562970:BTUS_RS01890 ^@ http://purl.uniprot.org/uniprot/D5WT40 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS08545 ^@ http://purl.uniprot.org/uniprot/D5WQ14 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS04900 ^@ http://purl.uniprot.org/uniprot/D5WW78 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/562970:BTUS_RS11010 ^@ http://purl.uniprot.org/uniprot/D5WRD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreD family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/562970:BTUS_RS05460 ^@ http://purl.uniprot.org/uniprot/D5WWX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS00725 ^@ http://purl.uniprot.org/uniprot/D5WRQ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/562970:BTUS_RS14485 ^@ http://purl.uniprot.org/uniprot/D5WVI8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/562970:BTUS_RS02845 ^@ http://purl.uniprot.org/uniprot/D5WU09 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/562970:BTUS_RS05500 ^@ http://purl.uniprot.org/uniprot/D5WWY1 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/562970:BTUS_RS09675 ^@ http://purl.uniprot.org/uniprot/D5WQL6 ^@ Similarity ^@ Belongs to the SleB family. http://togogenome.org/gene/562970:BTUS_RS00365 ^@ http://purl.uniprot.org/uniprot/D5WRI5 ^@ Function|||Similarity ^@ Belongs to the SpoVG family.|||Could be involved in septation. http://togogenome.org/gene/562970:BTUS_RS11545 ^@ http://purl.uniprot.org/uniprot/D5WS14 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS15605 ^@ http://purl.uniprot.org/uniprot/D5WWI5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/562970:BTUS_RS06105 ^@ http://purl.uniprot.org/uniprot/D5WXN3 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/562970:BTUS_RS15960 ^@ http://purl.uniprot.org/uniprot/D5WX37 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/562970:BTUS_RS11595 ^@ http://purl.uniprot.org/uniprot/D5WS24 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/562970:BTUS_RS05140 ^@ http://purl.uniprot.org/uniprot/D5WWQ9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS16525 ^@ http://purl.uniprot.org/uniprot/D5WXS6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/562970:BTUS_RS05170 ^@ http://purl.uniprot.org/uniprot/D5WWR5 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/562970:BTUS_RS16065 ^@ http://purl.uniprot.org/uniprot/D5WX59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/562970:BTUS_RS07530 ^@ http://purl.uniprot.org/uniprot/D5WPG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/562970:BTUS_RS00780 ^@ http://purl.uniprot.org/uniprot/D5WRR6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/562970:BTUS_RS16850 ^@ http://purl.uniprot.org/uniprot/D5WPY9 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/562970:BTUS_RS04350 ^@ http://purl.uniprot.org/uniprot/D5WVY1 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/562970:BTUS_RS12255 ^@ http://purl.uniprot.org/uniprot/D5WST7 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/562970:BTUS_RS11855 ^@ http://purl.uniprot.org/uniprot/D5WSK7 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/562970:BTUS_RS02990 ^@ http://purl.uniprot.org/uniprot/D5WUG8 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS07640 ^@ http://purl.uniprot.org/uniprot/D5WPI9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. PolC subfamily.|||Cytoplasm|||Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/562970:BTUS_RS16335 ^@ http://purl.uniprot.org/uniprot/D5WXB1 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/562970:BTUS_RS14420 ^@ http://purl.uniprot.org/uniprot/D5WV44 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/562970:BTUS_RS08060 ^@ http://purl.uniprot.org/uniprot/D5WPS1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/562970:BTUS_RS09105 ^@ http://purl.uniprot.org/uniprot/D5WQB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS16010 ^@ http://purl.uniprot.org/uniprot/D5WX48 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/562970:BTUS_RS07470 ^@ http://purl.uniprot.org/uniprot/D5WPF5 ^@ Similarity ^@ Belongs to the FlgD family. http://togogenome.org/gene/562970:BTUS_RS13545 ^@ http://purl.uniprot.org/uniprot/D5WUA2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS11390 ^@ http://purl.uniprot.org/uniprot/D5WRY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS03215 ^@ http://purl.uniprot.org/uniprot/D5WUK9 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/562970:BTUS_RS13830 ^@ http://purl.uniprot.org/uniprot/D5WUT6 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/562970:BTUS_RS05450 ^@ http://purl.uniprot.org/uniprot/D5WWX1 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/562970:BTUS_RS07405 ^@ http://purl.uniprot.org/uniprot/D5WPE2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/562970:BTUS_RS08575 ^@ http://purl.uniprot.org/uniprot/D5WQ20 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS08825 ^@ http://purl.uniprot.org/uniprot/D5WQ66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS08415 ^@ http://purl.uniprot.org/uniprot/D5WPY8 ^@ Caution|||Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS15620 ^@ http://purl.uniprot.org/uniprot/D5WWI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS04345 ^@ http://purl.uniprot.org/uniprot/D5WVY0 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/562970:BTUS_RS12490 ^@ http://purl.uniprot.org/uniprot/D5WTB4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/562970:BTUS_RS11755 ^@ http://purl.uniprot.org/uniprot/D5WSI9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS06420 ^@ http://purl.uniprot.org/uniprot/D5WXV5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/562970:BTUS_RS04830 ^@ http://purl.uniprot.org/uniprot/D5WW64 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/562970:BTUS_RS08970 ^@ http://purl.uniprot.org/uniprot/D5WQ84 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/562970:BTUS_RS12055 ^@ http://purl.uniprot.org/uniprot/D5WSP6 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/562970:BTUS_RS14890 ^@ http://purl.uniprot.org/uniprot/D5WVR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/562970:BTUS_RS07805 ^@ http://purl.uniprot.org/uniprot/D5WPL9 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/562970:BTUS_RS03490 ^@ http://purl.uniprot.org/uniprot/D5WUR0 ^@ Cofactor|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/562970:BTUS_RS11205 ^@ http://purl.uniprot.org/uniprot/D5WRV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS12610 ^@ http://purl.uniprot.org/uniprot/D5WTD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS03295 ^@ http://purl.uniprot.org/uniprot/D5WUM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS16280 ^@ http://purl.uniprot.org/uniprot/D5WXA1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS00810 ^@ http://purl.uniprot.org/uniprot/D5WRS2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/562970:BTUS_RS07325 ^@ http://purl.uniprot.org/uniprot/D5WPC5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 3 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS05480 ^@ http://purl.uniprot.org/uniprot/D5WWX7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS17165 ^@ http://purl.uniprot.org/uniprot/D5WWG4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/562970:BTUS_RS09325 ^@ http://purl.uniprot.org/uniprot/D5WQF7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/562970:BTUS_RS03575 ^@ http://purl.uniprot.org/uniprot/D5WUS7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS06470 ^@ http://purl.uniprot.org/uniprot/D5WXW4 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/562970:BTUS_RS03930 ^@ http://purl.uniprot.org/uniprot/D5WVC7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/562970:BTUS_RS03000 ^@ http://purl.uniprot.org/uniprot/D5WUH0 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/562970:BTUS_RS14945 ^@ http://purl.uniprot.org/uniprot/D5WVS9 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/562970:BTUS_RS03725 ^@ http://purl.uniprot.org/uniprot/D5WV88 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS04645 ^@ http://purl.uniprot.org/uniprot/D5WW33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein SsuA/TauA family.|||Cell membrane|||Membrane|||Periplasm http://togogenome.org/gene/562970:BTUS_RS12835 ^@ http://purl.uniprot.org/uniprot/D5WTI0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/562970:BTUS_RS00930 ^@ http://purl.uniprot.org/uniprot/D5WS72 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/562970:BTUS_RS16650 ^@ http://purl.uniprot.org/uniprot/D5WVA0 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/562970:BTUS_RS01105 ^@ http://purl.uniprot.org/uniprot/D5WSA7 ^@ Function|||Similarity ^@ Belongs to the PemK/MazF family.|||Toxic component of a type II toxin-antitoxin (TA) system. http://togogenome.org/gene/562970:BTUS_RS08425 ^@ http://purl.uniprot.org/uniprot/D5WPZ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/562970:BTUS_RS03415 ^@ http://purl.uniprot.org/uniprot/D5WUP7 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/562970:BTUS_RS16050 ^@ http://purl.uniprot.org/uniprot/D5WX56 ^@ Function|||Similarity ^@ Belongs to the complex I 30 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/562970:BTUS_RS03530 ^@ http://purl.uniprot.org/uniprot/D5WUR8 ^@ Function ^@ Required for transformation and DNA binding. http://togogenome.org/gene/562970:BTUS_RS07965 ^@ http://purl.uniprot.org/uniprot/D5WPQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/562970:BTUS_RS13325 ^@ http://purl.uniprot.org/uniprot/D5WU63 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS04140 ^@ http://purl.uniprot.org/uniprot/D5WVG5 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/562970:BTUS_RS08550 ^@ http://purl.uniprot.org/uniprot/D5WQ15 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS14165 ^@ http://purl.uniprot.org/uniprot/D5WV00 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/562970:BTUS_RS15755 ^@ http://purl.uniprot.org/uniprot/D5WWL5 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/562970:BTUS_RS06165 ^@ http://purl.uniprot.org/uniprot/D5WXP5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/562970:BTUS_RS07055 ^@ http://purl.uniprot.org/uniprot/D5WP70 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/562970:BTUS_RS08720 ^@ http://purl.uniprot.org/uniprot/D5WQ45 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/562970:BTUS_RS05505 ^@ http://purl.uniprot.org/uniprot/D5WWY2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS11170 ^@ http://purl.uniprot.org/uniprot/D5WRV1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/562970:BTUS_RS00795 ^@ http://purl.uniprot.org/uniprot/D5WRR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/562970:BTUS_RS11530 ^@ http://purl.uniprot.org/uniprot/D5WS11 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/562970:BTUS_RS04930 ^@ http://purl.uniprot.org/uniprot/D5WW85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS10840 ^@ http://purl.uniprot.org/uniprot/D5WRA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/562970:BTUS_RS16545 ^@ http://purl.uniprot.org/uniprot/D5WXT0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/562970:BTUS_RS09485 ^@ http://purl.uniprot.org/uniprot/D5WQI5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/562970:BTUS_RS01710 ^@ http://purl.uniprot.org/uniprot/D5WT06 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/562970:BTUS_RS02405 ^@ http://purl.uniprot.org/uniprot/D5WTS4 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/562970:BTUS_RS05335 ^@ http://purl.uniprot.org/uniprot/D5WWU7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS00910 ^@ http://purl.uniprot.org/uniprot/D5WS68 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/562970:BTUS_RS07270 ^@ http://purl.uniprot.org/uniprot/D5WPB4 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/562970:BTUS_RS02090 ^@ http://purl.uniprot.org/uniprot/D5WT78 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/562970:BTUS_RS13210 ^@ http://purl.uniprot.org/uniprot/D5WU39 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS12840 ^@ http://purl.uniprot.org/uniprot/D5WTI1 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/562970:BTUS_RS07850 ^@ http://purl.uniprot.org/uniprot/D5WPM8 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/562970:BTUS_RS13260 ^@ http://purl.uniprot.org/uniprot/D5WU48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS10090 ^@ http://purl.uniprot.org/uniprot/D5WQT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS14015 ^@ http://purl.uniprot.org/uniprot/D5WUX2 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/562970:BTUS_RS03570 ^@ http://purl.uniprot.org/uniprot/D5WUS6 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/562970:BTUS_RS15375 ^@ http://purl.uniprot.org/uniprot/D5WWD8 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/562970:BTUS_RS08780 ^@ http://purl.uniprot.org/uniprot/D5WQ57 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/562970:BTUS_RS02295 ^@ http://purl.uniprot.org/uniprot/D5WTQ2 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS01705 ^@ http://purl.uniprot.org/uniprot/D5WT05 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS09225 ^@ http://purl.uniprot.org/uniprot/D5WQD7 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/562970:BTUS_RS12335 ^@ http://purl.uniprot.org/uniprot/D5WSV2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. http://togogenome.org/gene/562970:BTUS_RS14445 ^@ http://purl.uniprot.org/uniprot/D5WV49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/562970:BTUS_RS01470 ^@ http://purl.uniprot.org/uniprot/D5WSI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS05705 ^@ http://purl.uniprot.org/uniprot/D5WXF2 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/562970:BTUS_RS09905 ^@ http://purl.uniprot.org/uniprot/D5WQQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS13410 ^@ http://purl.uniprot.org/uniprot/D5WU79 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/562970:BTUS_RS08935 ^@ http://purl.uniprot.org/uniprot/D5WQ77 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/562970:BTUS_RS09095 ^@ http://purl.uniprot.org/uniprot/D5WQB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpB family.|||Cytoplasm|||Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/562970:BTUS_RS10960 ^@ http://purl.uniprot.org/uniprot/D5WRC6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/562970:BTUS_RS14105 ^@ http://purl.uniprot.org/uniprot/D5WUZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS03910 ^@ http://purl.uniprot.org/uniprot/D5WVC3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/562970:BTUS_RS05825 ^@ http://purl.uniprot.org/uniprot/D5WXH6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS05290 ^@ http://purl.uniprot.org/uniprot/D5WWT9 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the IcmF family.|||Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.|||Homodimer.|||Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS13115 ^@ http://purl.uniprot.org/uniprot/D5WU20 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS09455 ^@ http://purl.uniprot.org/uniprot/D5WQI0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/562970:BTUS_RS09100 ^@ http://purl.uniprot.org/uniprot/D5WQB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpA family.|||Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Cytoplasm|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/562970:BTUS_RS15035 ^@ http://purl.uniprot.org/uniprot/D5WVU6 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/562970:BTUS_RS02585 ^@ http://purl.uniprot.org/uniprot/D5WTW2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. http://togogenome.org/gene/562970:BTUS_RS00740 ^@ http://purl.uniprot.org/uniprot/D5WRQ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/562970:BTUS_RS16270 ^@ http://purl.uniprot.org/uniprot/D5WX99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RpoE family.|||Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.|||RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors. http://togogenome.org/gene/562970:BTUS_RS04660 ^@ http://purl.uniprot.org/uniprot/D5WW36 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS13055 ^@ http://purl.uniprot.org/uniprot/D5WTM4 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/562970:BTUS_RS04165 ^@ http://purl.uniprot.org/uniprot/D5WVH0 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/562970:BTUS_RS08210 ^@ http://purl.uniprot.org/uniprot/D5WPU9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/562970:BTUS_RS03265 ^@ http://purl.uniprot.org/uniprot/D5WUL7 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/562970:BTUS_RS18630 ^@ http://purl.uniprot.org/uniprot/D5WQV0 ^@ Function|||Similarity ^@ Belongs to the uricase family.|||Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. http://togogenome.org/gene/562970:BTUS_RS00950 ^@ http://purl.uniprot.org/uniprot/D5WS76 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/562970:BTUS_RS04670 ^@ http://purl.uniprot.org/uniprot/D5WW38 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS11840 ^@ http://purl.uniprot.org/uniprot/D5WSK4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS11345 ^@ http://purl.uniprot.org/uniprot/D5WRY1 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/562970:BTUS_RS16005 ^@ http://purl.uniprot.org/uniprot/D5WX47 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS14100 ^@ http://purl.uniprot.org/uniprot/D5WUY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS11535 ^@ http://purl.uniprot.org/uniprot/D5WS12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS16830 ^@ http://purl.uniprot.org/uniprot/D5WPC3 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS10775 ^@ http://purl.uniprot.org/uniprot/D5WR89 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS15280 ^@ http://purl.uniprot.org/uniprot/D5WWC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS12305 ^@ http://purl.uniprot.org/uniprot/D5WSU6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS10920 ^@ http://purl.uniprot.org/uniprot/D5WRB8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/562970:BTUS_RS01200 ^@ http://purl.uniprot.org/uniprot/D5WSC8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiM family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/562970:BTUS_RS03400 ^@ http://purl.uniprot.org/uniprot/D5WUP4 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/562970:BTUS_RS12220 ^@ http://purl.uniprot.org/uniprot/D5WST0 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/562970:BTUS_RS07070 ^@ http://purl.uniprot.org/uniprot/D5WP73 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS00005 ^@ http://purl.uniprot.org/uniprot/D5WQZ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/562970:BTUS_RS03955 ^@ http://purl.uniprot.org/uniprot/D5WVD2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/562970:BTUS_RS15190 ^@ http://purl.uniprot.org/uniprot/D5WWA4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS17070 ^@ http://purl.uniprot.org/uniprot/D5WV07 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/562970:BTUS_RS02900 ^@ http://purl.uniprot.org/uniprot/D5WUF0 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/562970:BTUS_RS04435 ^@ http://purl.uniprot.org/uniprot/D5WVZ2 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/562970:BTUS_RS16220 ^@ http://purl.uniprot.org/uniprot/D5WX89 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS15955 ^@ http://purl.uniprot.org/uniprot/D5WX36 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/562970:BTUS_RS05745 ^@ http://purl.uniprot.org/uniprot/D5WXG0 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/562970:BTUS_RS02730 ^@ http://purl.uniprot.org/uniprot/D5WTY7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS08525 ^@ http://purl.uniprot.org/uniprot/D5WQ10 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/562970:BTUS_RS08090 ^@ http://purl.uniprot.org/uniprot/D5WPS7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/562970:BTUS_RS02340 ^@ http://purl.uniprot.org/uniprot/D5WTR1 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/562970:BTUS_RS00655 ^@ http://purl.uniprot.org/uniprot/D5WRP0 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/562970:BTUS_RS03285 ^@ http://purl.uniprot.org/uniprot/D5WUM1 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/562970:BTUS_RS03065 ^@ http://purl.uniprot.org/uniprot/D5WUI3 ^@ Function|||PTM|||Subcellular Location Annotation ^@ Autophosphorylated.|||Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/562970:BTUS_RS10605 ^@ http://purl.uniprot.org/uniprot/D5WR62 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/562970:BTUS_RS04265 ^@ http://purl.uniprot.org/uniprot/D5WVW5 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS14080 ^@ http://purl.uniprot.org/uniprot/D5WUY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/562970:BTUS_RS01925 ^@ http://purl.uniprot.org/uniprot/D5WT48 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS12715 ^@ http://purl.uniprot.org/uniprot/D5WTF8 ^@ Similarity ^@ Belongs to the PstS family. http://togogenome.org/gene/562970:BTUS_RS10180 ^@ http://purl.uniprot.org/uniprot/D5WQV2 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/562970:BTUS_RS16620 ^@ http://purl.uniprot.org/uniprot/D5WTU8 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/562970:BTUS_RS02985 ^@ http://purl.uniprot.org/uniprot/D5WUG6 ^@ Function|||Similarity ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. http://togogenome.org/gene/562970:BTUS_RS11315 ^@ http://purl.uniprot.org/uniprot/D5WRX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS07975 ^@ http://purl.uniprot.org/uniprot/D5WPQ4 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/562970:BTUS_RS10975 ^@ http://purl.uniprot.org/uniprot/D5WRC9 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/562970:BTUS_RS07440 ^@ http://purl.uniprot.org/uniprot/D5WPE9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS01575 ^@ http://purl.uniprot.org/uniprot/D5WSY1 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS00735 ^@ http://purl.uniprot.org/uniprot/D5WRQ7 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/562970:BTUS_RS06620 ^@ http://purl.uniprot.org/uniprot/D5WXZ4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS15370 ^@ http://purl.uniprot.org/uniprot/D5WWD7 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/562970:BTUS_RS03270 ^@ http://purl.uniprot.org/uniprot/D5WUL8 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/562970:BTUS_RS09185 ^@ http://purl.uniprot.org/uniprot/D5WQC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS00575 ^@ http://purl.uniprot.org/uniprot/D5WRM6 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/562970:BTUS_RS11050 ^@ http://purl.uniprot.org/uniprot/D5WRE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/562970:BTUS_RS02315 ^@ http://purl.uniprot.org/uniprot/D5WTQ6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS06885 ^@ http://purl.uniprot.org/uniprot/D5WY39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).|||Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3). http://togogenome.org/gene/562970:BTUS_RS15990 ^@ http://purl.uniprot.org/uniprot/D5WX43 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS12590 ^@ http://purl.uniprot.org/uniprot/D5WTD4 ^@ Similarity ^@ Belongs to the acylphosphatase family.|||Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/562970:BTUS_RS11955 ^@ http://purl.uniprot.org/uniprot/D5WSM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CotF family.|||Spore coat http://togogenome.org/gene/562970:BTUS_RS02860 ^@ http://purl.uniprot.org/uniprot/D5WU12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/562970:BTUS_RS16370 ^@ http://purl.uniprot.org/uniprot/D5WXB8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/562970:BTUS_RS13910 ^@ http://purl.uniprot.org/uniprot/D5WUV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS12875 ^@ http://purl.uniprot.org/uniprot/D5WTI8 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/562970:BTUS_RS12175 ^@ http://purl.uniprot.org/uniprot/D5WSS1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/562970:BTUS_RS01450 ^@ http://purl.uniprot.org/uniprot/D5WSH6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS00870 ^@ http://purl.uniprot.org/uniprot/D5WS60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/562970:BTUS_RS09215 ^@ http://purl.uniprot.org/uniprot/D5WQD5 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/562970:BTUS_RS03925 ^@ http://purl.uniprot.org/uniprot/D5WVC6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/562970:BTUS_RS04875 ^@ http://purl.uniprot.org/uniprot/D5WW73 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS01205 ^@ http://purl.uniprot.org/uniprot/D5WSC9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiN family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/562970:BTUS_RS06040 ^@ http://purl.uniprot.org/uniprot/D5WXM0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/562970:BTUS_RS07255 ^@ http://purl.uniprot.org/uniprot/D5WPB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/562970:BTUS_RS00625 ^@ http://purl.uniprot.org/uniprot/D5WRN4 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/562970:BTUS_RS00750 ^@ http://purl.uniprot.org/uniprot/D5WRR0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/562970:BTUS_RS01480 ^@ http://purl.uniprot.org/uniprot/D5WSI2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/562970:BTUS_RS06490 ^@ http://purl.uniprot.org/uniprot/D5WXW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/562970:BTUS_RS01140 ^@ http://purl.uniprot.org/uniprot/D5WSB5 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/562970:BTUS_RS07645 ^@ http://purl.uniprot.org/uniprot/D5WPJ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/562970:BTUS_RS05695 ^@ http://purl.uniprot.org/uniprot/D5WXF0 ^@ Similarity ^@ Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. http://togogenome.org/gene/562970:BTUS_RS07220 ^@ http://purl.uniprot.org/uniprot/D5WPA4 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/562970:BTUS_RS16015 ^@ http://purl.uniprot.org/uniprot/D5WX49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.|||Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS13630 ^@ http://purl.uniprot.org/uniprot/D5WUB9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/562970:BTUS_RS02010 ^@ http://purl.uniprot.org/uniprot/D5WT62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. EmrB family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS11420 ^@ http://purl.uniprot.org/uniprot/D5WRZ5 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/562970:BTUS_RS13415 ^@ http://purl.uniprot.org/uniprot/D5WU80 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/562970:BTUS_RS10550 ^@ http://purl.uniprot.org/uniprot/D5WR51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS12915 ^@ http://purl.uniprot.org/uniprot/D5WTJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS07215 ^@ http://purl.uniprot.org/uniprot/D5WPA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/562970:BTUS_RS14030 ^@ http://purl.uniprot.org/uniprot/D5WUX6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS17170 ^@ http://purl.uniprot.org/uniprot/D5WWH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/562970:BTUS_RS06110 ^@ http://purl.uniprot.org/uniprot/D5WXN4 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/562970:BTUS_RS00335 ^@ http://purl.uniprot.org/uniprot/D5WRH9 ^@ Function|||Similarity ^@ Belongs to the peptidase S51 family.|||Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides. http://togogenome.org/gene/562970:BTUS_RS03320 ^@ http://purl.uniprot.org/uniprot/D5WUM8 ^@ Similarity ^@ Belongs to the Ahb/Nir family. http://togogenome.org/gene/562970:BTUS_RS04555 ^@ http://purl.uniprot.org/uniprot/D5WW16 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/562970:BTUS_RS00835 ^@ http://purl.uniprot.org/uniprot/D5WS53 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/562970:BTUS_RS12295 ^@ http://purl.uniprot.org/uniprot/D5WSU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/562970:BTUS_RS09165 ^@ http://purl.uniprot.org/uniprot/D5WQC5 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/562970:BTUS_RS01520 ^@ http://purl.uniprot.org/uniprot/D5WSX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS06090 ^@ http://purl.uniprot.org/uniprot/D5WXN0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/562970:BTUS_RS07670 ^@ http://purl.uniprot.org/uniprot/D5WPJ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/562970:BTUS_RS04110 ^@ http://purl.uniprot.org/uniprot/D5WVF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/562970:BTUS_RS03520 ^@ http://purl.uniprot.org/uniprot/D5WUR6 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/562970:BTUS_RS04785 ^@ http://purl.uniprot.org/uniprot/D5WW57 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS02170 ^@ http://purl.uniprot.org/uniprot/D5WT93 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/562970:BTUS_RS13440 ^@ http://purl.uniprot.org/uniprot/D5WU84 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/562970:BTUS_RS07705 ^@ http://purl.uniprot.org/uniprot/D5WPK1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS09195 ^@ http://purl.uniprot.org/uniprot/D5WQD1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/562970:BTUS_RS12605 ^@ http://purl.uniprot.org/uniprot/D5WTD7 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/562970:BTUS_RS00385 ^@ http://purl.uniprot.org/uniprot/D5WRI9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/562970:BTUS_RS02365 ^@ http://purl.uniprot.org/uniprot/D5WTR6 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/562970:BTUS_RS13135 ^@ http://purl.uniprot.org/uniprot/D5WU24 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/562970:BTUS_RS08760 ^@ http://purl.uniprot.org/uniprot/D5WQ53 ^@ Similarity|||Subunit ^@ Belongs to the MtrB family.|||Oligomer of 11 identical subunits arranged in doughnut-like structure. http://togogenome.org/gene/562970:BTUS_RS14435 ^@ http://purl.uniprot.org/uniprot/D5WV47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/562970:BTUS_RS04490 ^@ http://purl.uniprot.org/uniprot/D5WW04 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/562970:BTUS_RS02510 ^@ http://purl.uniprot.org/uniprot/D5WTU6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS02050 ^@ http://purl.uniprot.org/uniprot/D5WT70 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/562970:BTUS_RS14055 ^@ http://purl.uniprot.org/uniprot/D5WUY1 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/562970:BTUS_RS01990 ^@ http://purl.uniprot.org/uniprot/D5WT58 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/562970:BTUS_RS03945 ^@ http://purl.uniprot.org/uniprot/D5WVD0 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/562970:BTUS_RS13275 ^@ http://purl.uniprot.org/uniprot/D5WU51 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/562970:BTUS_RS12445 ^@ http://purl.uniprot.org/uniprot/D5WTA5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/562970:BTUS_RS07310 ^@ http://purl.uniprot.org/uniprot/D5WPC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS00030 ^@ http://purl.uniprot.org/uniprot/D5WQZ7 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/562970:BTUS_RS14605 ^@ http://purl.uniprot.org/uniprot/D5WVL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS12625 ^@ http://purl.uniprot.org/uniprot/D5WTE1 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/562970:BTUS_RS02675 ^@ http://purl.uniprot.org/uniprot/D5WTX7 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/562970:BTUS_RS02325 ^@ http://purl.uniprot.org/uniprot/D5WTQ8 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. UBA5 subfamily. http://togogenome.org/gene/562970:BTUS_RS08390 ^@ http://purl.uniprot.org/uniprot/D5WPY3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/562970:BTUS_RS10965 ^@ http://purl.uniprot.org/uniprot/D5WRC7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/562970:BTUS_RS09340 ^@ http://purl.uniprot.org/uniprot/D5WQG0 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/562970:BTUS_RS16530 ^@ http://purl.uniprot.org/uniprot/D5WXS7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS16515 ^@ http://purl.uniprot.org/uniprot/D5WXS4 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/562970:BTUS_RS03385 ^@ http://purl.uniprot.org/uniprot/D5WUP1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/562970:BTUS_RS08455 ^@ http://purl.uniprot.org/uniprot/D5WPZ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/562970:BTUS_RS02175 ^@ http://purl.uniprot.org/uniprot/D5WT94 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/562970:BTUS_RS08860 ^@ http://purl.uniprot.org/uniprot/D5WQ74 ^@ Similarity ^@ Belongs to the phosphosulfolactate synthase family. http://togogenome.org/gene/562970:BTUS_RS08520 ^@ http://purl.uniprot.org/uniprot/D5WQ09 ^@ Similarity ^@ Belongs to the prephenate/arogenate dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS02155 ^@ http://purl.uniprot.org/uniprot/D5WT90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/562970:BTUS_RS07245 ^@ http://purl.uniprot.org/uniprot/D5WPA9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/562970:BTUS_RS05315 ^@ http://purl.uniprot.org/uniprot/D5WWU4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/562970:BTUS_RS15885 ^@ http://purl.uniprot.org/uniprot/D5WX22 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/562970:BTUS_RS05965 ^@ http://purl.uniprot.org/uniprot/D5WXK5 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.