http://togogenome.org/gene/568768:Dpoa569_RS18535 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/568768:Dpoa569_RS10920 ^@ http://purl.uniprot.org/uniprot/A0A5B8HLF6 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/568768:Dpoa569_RS00515 ^@ http://purl.uniprot.org/uniprot/A0A5B8HDQ3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS18145 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AFG1 ATPase family. ZapE subfamily.|||Cytoplasm|||Interacts with FtsZ.|||Reduces the stability of FtsZ polymers in the presence of ATP. http://togogenome.org/gene/568768:Dpoa569_RS18510 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBS3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RfaH family.|||Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.|||Interacts with both the nontemplate DNA and the RNA polymerase (RNAP). http://togogenome.org/gene/568768:Dpoa569_RS01200 ^@ http://purl.uniprot.org/uniprot/A0A5B8HE59 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/568768:Dpoa569_RS13455 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE08 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS03985 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2X5 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/568768:Dpoa569_RS00425 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS13330 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9B5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/568768:Dpoa569_RS06465 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4H0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the rusA family.|||Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC.|||Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS03770 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2S3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol monophosphatase superfamily. CysQ family.|||Cell inner membrane|||Converts adenosine-3',5'-bisphosphate (PAP) to AMP. http://togogenome.org/gene/568768:Dpoa569_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0208 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07530 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3P5 ^@ Function|||Similarity ^@ Belongs to the thiamine kinase family.|||Catalyzes the phosphorylation of thiamine to thiamine phosphate. http://togogenome.org/gene/568768:Dpoa569_RS02215 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZX6 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/568768:Dpoa569_RS10160 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.|||Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS11315 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS13235 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8N9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10525 ^@ http://purl.uniprot.org/uniprot/A0A5B8I744 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/568768:Dpoa569_RS15200 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAD6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/568768:Dpoa569_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6W1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04560 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICP1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||In the N-terminal section; belongs to the FGAMS family.|||Monomer.|||Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. http://togogenome.org/gene/568768:Dpoa569_RS13045 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDQ0 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/568768:Dpoa569_RS05675 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS12305 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMJ7 ^@ Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family. http://togogenome.org/gene/568768:Dpoa569_RS13565 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS05780 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8T7 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/568768:Dpoa569_RS14520 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEP5 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/568768:Dpoa569_RS14685 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRH5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/568768:Dpoa569_RS01525 ^@ http://purl.uniprot.org/uniprot/A0A5B8I126 ^@ Function|||Similarity ^@ Belongs to the frataxin family.|||Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. http://togogenome.org/gene/568768:Dpoa569_RS08940 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7V4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.|||Cytoplasm|||Interacts with TusE. http://togogenome.org/gene/568768:Dpoa569_RS11870 ^@ http://purl.uniprot.org/uniprot/A0A5B8HP93 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS11480 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10695 ^@ http://purl.uniprot.org/uniprot/A0A5B8HL85 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/568768:Dpoa569_RS02175 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1P5 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/568768:Dpoa569_RS07225 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9P1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively. http://togogenome.org/gene/568768:Dpoa569_RS01355 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0X7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/568768:Dpoa569_RS00575 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5M3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family.|||Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS13650 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9I0 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family. AroL subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||The LID domain closes over the active site upon ATP binding. http://togogenome.org/gene/568768:Dpoa569_RS12695 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPX9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/568768:Dpoa569_RS11375 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9K1 ^@ Similarity ^@ Belongs to the flavodoxin family. http://togogenome.org/gene/568768:Dpoa569_RS18210 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRJ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the KdsC family.|||Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS07635 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3R7 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/568768:Dpoa569_RS07915 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5H9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Binds 1 nickel ion per subunit.|||Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/568768:Dpoa569_RS10940 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNI7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS03555 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFX2 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/568768:Dpoa569_RS00280 ^@ http://purl.uniprot.org/uniprot/A0A5B8HDP6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS02230 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEY9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07295 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKJ8 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/568768:Dpoa569_RS03540 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0W2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/568768:Dpoa569_RS01380 ^@ http://purl.uniprot.org/uniprot/A0A5B8HE91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS07265 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSK3 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/568768:Dpoa569_RS12850 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS17905 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 32 family.|||Cytoplasm|||Enables the bacterium to metabolize sucrose as a sole carbon source. http://togogenome.org/gene/568768:Dpoa569_RS13280 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9A5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS12390 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6Q9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS12470 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA81 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS16415 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSJ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/568768:Dpoa569_RS08935 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HflD family.|||Cell membrane|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS03325 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS17390 ^@ http://purl.uniprot.org/uniprot/A0A5B8HR27 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS13465 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ62 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A5B8I681 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.|||Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10585 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNC7 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/568768:Dpoa569_RS02645 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGK4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS03400 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6Y6 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS02405 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1R6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD). http://togogenome.org/gene/568768:Dpoa569_RS13065 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8V2 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15175 ^@ http://purl.uniprot.org/uniprot/A0A5B8HR62 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS13270 ^@ http://purl.uniprot.org/uniprot/A0A5B8I904 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/568768:Dpoa569_RS14925 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEX7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds 1 Fe(2+) cation per monomer.|||Binds 1 nickel ion per monomer.|||Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS05770 ^@ http://purl.uniprot.org/uniprot/A0A5B8I610 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/568768:Dpoa569_RS15710 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA29 ^@ Similarity ^@ Belongs to the acetyltransferase family. YpeA subfamily. http://togogenome.org/gene/568768:Dpoa569_RS12115 ^@ http://purl.uniprot.org/uniprot/A0A5B8IER0 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/568768:Dpoa569_RS02590 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGJ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS16435 ^@ http://purl.uniprot.org/uniprot/A0A5B8II63 ^@ Similarity ^@ Belongs to the alpha-acetolactate decarboxylase family. http://togogenome.org/gene/568768:Dpoa569_RS13830 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7P7 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/568768:Dpoa569_RS15230 ^@ http://purl.uniprot.org/uniprot/A0A5B8HR74 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/568768:Dpoa569_RS01625 ^@ http://purl.uniprot.org/uniprot/A0A5B8I155 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/568768:Dpoa569_RS19260 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID22 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/568768:Dpoa569_RS12950 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAH0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS14060 ^@ http://purl.uniprot.org/uniprot/A0A5B8I955 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS05970 ^@ http://purl.uniprot.org/uniprot/A0A5B8I483 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS16920 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAT4 ^@ Similarity ^@ Belongs to the CcdB toxin family. http://togogenome.org/gene/568768:Dpoa569_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGL9 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/568768:Dpoa569_RS02550 ^@ http://purl.uniprot.org/uniprot/A0A5B8I224 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/568768:Dpoa569_RS12515 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPU7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane|||Required for nicotinamide riboside transport across the inner membrane. http://togogenome.org/gene/568768:Dpoa569_RS02580 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1Z1 ^@ Function|||Similarity ^@ Belongs to the MurCDEF family. Mpl subfamily.|||Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate. http://togogenome.org/gene/568768:Dpoa569_RS12990 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ32 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/568768:Dpoa569_RS11235 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7I1 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/568768:Dpoa569_RS18600 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAU8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS07755 ^@ http://purl.uniprot.org/uniprot/A0A5B8I586 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PqiA family.|||Component of a transport pathway that contributes to membrane integrity.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS05915 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEZ5 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/568768:Dpoa569_RS18610 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBV8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/568768:Dpoa569_RS02655 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2A0 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS05530 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3X8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/568768:Dpoa569_RS11230 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7T8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/568768:Dpoa569_RS12455 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMP4 ^@ Similarity ^@ Belongs to the ModE family. http://togogenome.org/gene/568768:Dpoa569_RS02545 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6D3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS02640 ^@ http://purl.uniprot.org/uniprot/A0A5B8HF84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS02690 ^@ http://purl.uniprot.org/uniprot/A0A5B8HF90 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/568768:Dpoa569_RS13595 ^@ http://purl.uniprot.org/uniprot/A0A5B8ILN2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell inner membrane|||Component of the transport system for branched-chain amino acids.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS12815 ^@ http://purl.uniprot.org/uniprot/A0A5B8IF69 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/568768:Dpoa569_RS01120 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0R8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/568768:Dpoa569_RS11215 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE57 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/568768:Dpoa569_RS11710 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7U1 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/568768:Dpoa569_RS03895 ^@ http://purl.uniprot.org/uniprot/A0A5B8IL23 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.|||Homooctamer. http://togogenome.org/gene/568768:Dpoa569_RS13815 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS01400 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0Z5 ^@ Function|||Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family.|||Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate. http://togogenome.org/gene/568768:Dpoa569_RS03620 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2Z1 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/568768:Dpoa569_RS11740 ^@ http://purl.uniprot.org/uniprot/A0A5B8HM60 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/568768:Dpoa569_RS08695 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJL8 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS05660 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8M5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS13165 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFQ1 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RcsD family.|||Cell inner membrane|||Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.|||Interacts with RcsC and RcsB.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylated by RcsC. http://togogenome.org/gene/568768:Dpoa569_RS17415 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJ31 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/568768:Dpoa569_RS13610 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNN3 ^@ Function ^@ Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals. http://togogenome.org/gene/568768:Dpoa569_RS07775 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA54 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/568768:Dpoa569_RS00640 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0G2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sulfur carrier protein TusA family.|||Cytoplasm|||Interacts with IscS.|||Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. http://togogenome.org/gene/568768:Dpoa569_RS02970 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHG7 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/568768:Dpoa569_RS17290 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJ01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS12750 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDH1 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS14005 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQY1 ^@ Function ^@ Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. http://togogenome.org/gene/568768:Dpoa569_RS11355 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7J7 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese.|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS08080 ^@ http://purl.uniprot.org/uniprot/A0A5B8I422 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/568768:Dpoa569_RS11805 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICW2 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15415 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15895 ^@ http://purl.uniprot.org/uniprot/A0A5B8IHN5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GSP I family.|||Cell inner membrane|||Cleaved by prepilin peptidase.|||Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.|||Membrane|||Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. http://togogenome.org/gene/568768:Dpoa569_RS12600 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS13390 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8S2 ^@ Function|||Similarity ^@ A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.|||Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily. http://togogenome.org/gene/568768:Dpoa569_RS12630 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8U7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. http://togogenome.org/gene/568768:Dpoa569_RS01510 ^@ http://purl.uniprot.org/uniprot/A0A5B8I656 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/568768:Dpoa569_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A5B8HF13 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/568768:Dpoa569_RS16810 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAR7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS05865 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8R2 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/568768:Dpoa569_RS19200 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS12145 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPF9 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5Y4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/568768:Dpoa569_RS00805 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0J8 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A5B8I611 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/568768:Dpoa569_RS04605 ^@ http://purl.uniprot.org/uniprot/A0A5B8I571 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS08380 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJC8 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/568768:Dpoa569_RS05775 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cell membrane|||In the C-terminal section; belongs to the complex I 49 kDa subunit family.|||In the N-terminal section; belongs to the complex I 30 kDa subunit family.|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/568768:Dpoa569_RS00020 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID62 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/568768:Dpoa569_RS15735 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NRAMP family.|||Cell membrane|||H(+)-stimulated, divalent metal cation uptake system. http://togogenome.org/gene/568768:Dpoa569_RS09650 ^@ http://purl.uniprot.org/uniprot/A0A5B8HK59 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS02130 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEW1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/568768:Dpoa569_RS05515 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2D5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OmpP1/FadL family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6G1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.|||Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS10195 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5B9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07560 ^@ http://purl.uniprot.org/uniprot/A0A5B8I701 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2G3 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/568768:Dpoa569_RS09100 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7Z5 ^@ Similarity ^@ Belongs to the fructosamine kinase family. http://togogenome.org/gene/568768:Dpoa569_RS04910 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGP9 ^@ Similarity ^@ Belongs to the UPF0319 family. http://togogenome.org/gene/568768:Dpoa569_RS09160 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICR0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. PCD1 subfamily. http://togogenome.org/gene/568768:Dpoa569_RS04930 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJ29 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dsrC/tusE family.|||Cytoplasm|||Interacts with the TusBCD complex. Interacts with MnmA.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD. http://togogenome.org/gene/568768:Dpoa569_RS02960 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10215 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS19050 ^@ http://purl.uniprot.org/uniprot/A0A5B8HUC2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/568768:Dpoa569_RS11700 ^@ http://purl.uniprot.org/uniprot/A0A5B8HP37 ^@ Similarity ^@ Belongs to the IucA/IucC family. http://togogenome.org/gene/568768:Dpoa569_RS10480 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS11145 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICE0 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/568768:Dpoa569_RS17385 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFE3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15495 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAJ6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS12900 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. MrdA subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS10710 ^@ http://purl.uniprot.org/uniprot/A0A5B8I971 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS18835 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04995 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS07195 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3H2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS00885 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5F9 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. http://togogenome.org/gene/568768:Dpoa569_RS00880 ^@ http://purl.uniprot.org/uniprot/A0A5B8HF76 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS10125 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8Q5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.|||Cell membrane|||Efflux system for nickel and cobalt.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS03630 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7J6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS12445 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8M6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/568768:Dpoa569_RS13255 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAP7 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS17655 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJA4 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS13380 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7C3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS10830 ^@ http://purl.uniprot.org/uniprot/A0A5B8I994 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJK5 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS01130 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFF2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/568768:Dpoa569_RS03720 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2R0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS10960 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7M4 ^@ Similarity ^@ Belongs to the UPF0352 family. http://togogenome.org/gene/568768:Dpoa569_RS15600 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA05 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS16785 ^@ http://purl.uniprot.org/uniprot/A0A5B8IIE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16745 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBC5 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/568768:Dpoa569_RS16875 ^@ http://purl.uniprot.org/uniprot/A0A5B8III3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CutA family.|||Cytoplasm|||Homotrimer.|||Involved in resistance toward heavy metals.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS08990 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7X0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A5B8HE33 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.|||Cell inner membrane|||Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.|||Homodimer.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04245 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHZ4 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/568768:Dpoa569_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A5B8HG93 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/568768:Dpoa569_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHC2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS07310 ^@ http://purl.uniprot.org/uniprot/A0A5B8I543 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/568768:Dpoa569_RS15105 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS13895 ^@ http://purl.uniprot.org/uniprot/A0A5B8I929 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/568768:Dpoa569_RS07690 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5B6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS02105 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6L0 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/568768:Dpoa569_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6T7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS10755 ^@ http://purl.uniprot.org/uniprot/A0A5B8HL99 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/568768:Dpoa569_RS03050 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2B5 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/568768:Dpoa569_RS09135 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJV9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS07625 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBJ8 ^@ Function|||Similarity ^@ Belongs to the glutathione peroxidase family. BtuE subfamily.|||Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. http://togogenome.org/gene/568768:Dpoa569_RS03120 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6S4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS05420 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS12760 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPS4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).|||Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS10355 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5G2 ^@ Cofactor ^@ Binds 2 Mg(2+) ions per monomer. http://togogenome.org/gene/568768:Dpoa569_RS13395 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNG2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/568768:Dpoa569_RS01285 ^@ http://purl.uniprot.org/uniprot/A0A5B8I604 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/568768:Dpoa569_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7X6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/568768:Dpoa569_RS09520 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6D5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS16705 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQN3 ^@ Cofactor|||Similarity ^@ Belongs to the ApbE family.|||Magnesium. Can also use manganese. http://togogenome.org/gene/568768:Dpoa569_RS01680 ^@ http://purl.uniprot.org/uniprot/A0A5B8I175 ^@ Function|||Similarity ^@ Belongs to the glycosyl hydrolase 13 family.|||Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin. http://togogenome.org/gene/568768:Dpoa569_RS12735 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8D0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS13245 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQA7 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. http://togogenome.org/gene/568768:Dpoa569_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0Z2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/568768:Dpoa569_RS05045 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5L3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS18400 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJY6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/568768:Dpoa569_RS16240 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQE0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS11265 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNS7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/568768:Dpoa569_RS13265 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFS4 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/568768:Dpoa569_RS12920 ^@ http://purl.uniprot.org/uniprot/A0A5B8I919 ^@ Similarity ^@ Belongs to the UPF0250 family. http://togogenome.org/gene/568768:Dpoa569_RS01185 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFG8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS15770 ^@ http://purl.uniprot.org/uniprot/A0A5B8HS61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/568768:Dpoa569_RS10785 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNF1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS10120 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBP2 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/568768:Dpoa569_RS12840 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDI3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS00090 ^@ http://purl.uniprot.org/uniprot/A0A5B8HUM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/568768:Dpoa569_RS04105 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoS subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. http://togogenome.org/gene/568768:Dpoa569_RS05890 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2M4 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/568768:Dpoa569_RS12895 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS07525 ^@ http://purl.uniprot.org/uniprot/A0A5B8I582 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LpoB family.|||Cell outer membrane|||Interacts with PBP1b.|||Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). http://togogenome.org/gene/568768:Dpoa569_RS01025 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTL6 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.|||Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). http://togogenome.org/gene/568768:Dpoa569_RS12740 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMX2 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/568768:Dpoa569_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A5B8I546 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/568768:Dpoa569_RS12480 ^@ http://purl.uniprot.org/uniprot/A0A5B8IF23 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS01010 ^@ http://purl.uniprot.org/uniprot/A0A5B8IET9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS05430 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJF0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.|||Cell inner membrane|||Component of an export pathway for enterobactin.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS00110 ^@ http://purl.uniprot.org/uniprot/A0A5Q2V5C1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS07535 ^@ http://purl.uniprot.org/uniprot/A0A5B8I591 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.|||Cytoplasm|||Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. http://togogenome.org/gene/568768:Dpoa569_RS18165 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTQ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS15960 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRM0 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/568768:Dpoa569_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5S9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/568768:Dpoa569_RS13000 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAI6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/568768:Dpoa569_RS04815 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7W6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PsiE family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS19250 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICN3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/568768:Dpoa569_RS04015 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7R9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/568768:Dpoa569_RS11095 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS00700 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0H3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10640 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS13205 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAN5 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/568768:Dpoa569_RS10790 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDV6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/568768:Dpoa569_RS12700 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDF5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4Z5 ^@ Function|||Similarity ^@ Belongs to the FlgN family.|||Required for the efficient initiation of filament assembly. http://togogenome.org/gene/568768:Dpoa569_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFG6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SNF2/RAD54 helicase family. RapA subfamily.|||Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.|||Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair. http://togogenome.org/gene/568768:Dpoa569_RS16040 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQA3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS02055 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1P0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/568768:Dpoa569_RS09285 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBS6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DbpA subfamily.|||Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.|||Cytoplasm|||DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. http://togogenome.org/gene/568768:Dpoa569_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapB family.|||Cytoplasm|||Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.|||Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. http://togogenome.org/gene/568768:Dpoa569_RS09840 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS12625 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6V8 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/568768:Dpoa569_RS15565 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS14455 ^@ http://purl.uniprot.org/uniprot/A0A5B8HR89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16835 ^@ http://purl.uniprot.org/uniprot/A0A5B8HS15 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPAT/DAPAT family.|||Cell membrane|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/568768:Dpoa569_RS13180 ^@ http://purl.uniprot.org/uniprot/A0A5B8I978 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/568768:Dpoa569_RS02180 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEX3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/568768:Dpoa569_RS10470 ^@ http://purl.uniprot.org/uniprot/A0A5B8I733 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/568768:Dpoa569_RS12280 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEU2 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/568768:Dpoa569_RS00945 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0M7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18035 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBS9 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/568768:Dpoa569_RS01215 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZ57 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/568768:Dpoa569_RS13340 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNF2 ^@ Similarity ^@ Belongs to the Hha/YmoA/Cnu family. http://togogenome.org/gene/568768:Dpoa569_RS18545 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC43 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiJ family.|||Cytoplasm|||Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates. http://togogenome.org/gene/568768:Dpoa569_RS18220 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJN5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptA family.|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS10825 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC59 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS17380 ^@ http://purl.uniprot.org/uniprot/A0A5B8IB21 ^@ Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family. AlsE subfamily.|||Catalyzes the reversible epimerization of D-allulose 6-phosphate to D-fructose 6-phosphate. Can also catalyze with lower efficiency the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/568768:Dpoa569_RS03230 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFP5 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/568768:Dpoa569_RS01945 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEK6 ^@ Similarity ^@ Belongs to the phosphoribulokinase family. http://togogenome.org/gene/568768:Dpoa569_RS03195 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the N-Me-Phe pilin family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07605 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKM2 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family. NagK subfamily.|||Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. http://togogenome.org/gene/568768:Dpoa569_RS15470 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0114 family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10060 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKI2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/568768:Dpoa569_RS02390 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6S6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FrdD family.|||Cell membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. http://togogenome.org/gene/568768:Dpoa569_RS01705 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5W2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GlpE family.|||Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS04300 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7L1 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/568768:Dpoa569_RS16485 ^@ http://purl.uniprot.org/uniprot/A0A5B8II45 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/568768:Dpoa569_RS10280 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBS8 ^@ Similarity ^@ Belongs to the D-alanine--D-alanine ligase family. http://togogenome.org/gene/568768:Dpoa569_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1V0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.|||Homodimer.|||With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P. http://togogenome.org/gene/568768:Dpoa569_RS03925 ^@ http://purl.uniprot.org/uniprot/A0A5B8I174 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.|||Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.|||Homodimer.|||In the C-terminal section; belongs to the cytidylyltransferase family.|||In the N-terminal section; belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/568768:Dpoa569_RS10805 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7G7 ^@ Cofactor|||Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/568768:Dpoa569_RS01895 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS13765 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07245 ^@ http://purl.uniprot.org/uniprot/A0A5B8I530 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/568768:Dpoa569_RS09210 ^@ http://purl.uniprot.org/uniprot/A0A5B8I814 ^@ Function|||Similarity|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ. http://togogenome.org/gene/568768:Dpoa569_RS19000 ^@ http://purl.uniprot.org/uniprot/A0A5B8HUA8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 2 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIF9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/568768:Dpoa569_RS05895 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4B4 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/568768:Dpoa569_RS16715 ^@ http://purl.uniprot.org/uniprot/A0A5B8IIC8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ApbE family.|||Cell inner membrane|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/568768:Dpoa569_RS07750 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5E5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.|||Cytoplasm|||Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity. http://togogenome.org/gene/568768:Dpoa569_RS09035 ^@ http://purl.uniprot.org/uniprot/A0A5B8HM10 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS01555 ^@ http://purl.uniprot.org/uniprot/A0A5B8HED1 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/568768:Dpoa569_RS04765 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIY3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/568768:Dpoa569_RS11270 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE66 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS12310 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPP7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS07910 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBV9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase T family.|||Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.|||Homodimer.|||Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. http://togogenome.org/gene/568768:Dpoa569_RS10965 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7C6 ^@ Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||Membrane|||To H.influenzae HI_0842. http://togogenome.org/gene/568768:Dpoa569_RS17210 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQZ3 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/568768:Dpoa569_RS03675 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFZ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS13485 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7E9 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/568768:Dpoa569_RS15360 ^@ http://purl.uniprot.org/uniprot/A0A5B8IHC3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS13005 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPW4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS01835 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZN6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS17765 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJE1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/568768:Dpoa569_RS03970 ^@ http://purl.uniprot.org/uniprot/A0A5B8I321 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.|||Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily. http://togogenome.org/gene/568768:Dpoa569_RS13900 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQV7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/568768:Dpoa569_RS16215 ^@ http://purl.uniprot.org/uniprot/A0A5B8IB18 ^@ Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase class-III family. http://togogenome.org/gene/568768:Dpoa569_RS03150 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2E2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecM family.|||Periplasm|||Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.|||cytosol http://togogenome.org/gene/568768:Dpoa569_RS13230 ^@ http://purl.uniprot.org/uniprot/A0A5B8I989 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/568768:Dpoa569_RS12745 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPY8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS16925 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQT7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/568768:Dpoa569_RS10875 ^@ http://purl.uniprot.org/uniprot/A0A5B8HLD8 ^@ Similarity ^@ Belongs to the elongation factor P family. http://togogenome.org/gene/568768:Dpoa569_RS03100 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2C6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS12935 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN26 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TatA/E family. TatE subfamily.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA. http://togogenome.org/gene/568768:Dpoa569_RS13980 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9D6 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/568768:Dpoa569_RS15085 ^@ http://purl.uniprot.org/uniprot/A0A5B8HR52 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/568768:Dpoa569_RS13570 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ94 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/568768:Dpoa569_RS08475 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5R7 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS15820 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA56 ^@ Similarity ^@ Belongs to the VapB family. http://togogenome.org/gene/568768:Dpoa569_RS12495 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8N5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS08655 ^@ http://purl.uniprot.org/uniprot/A0A5B8HLT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS09750 ^@ http://purl.uniprot.org/uniprot/A0A5B8I509 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Cob(I)alamin adenosyltransferase family.|||Cytoplasm|||Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. http://togogenome.org/gene/568768:Dpoa569_RS16470 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAL4 ^@ Function ^@ DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. http://togogenome.org/gene/568768:Dpoa569_RS09670 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8B6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the arabinose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of L-arabinose to L-ribulose.|||Homohexamer. http://togogenome.org/gene/568768:Dpoa569_RS08060 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7E5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18375 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTW4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/568768:Dpoa569_RS19340 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEP0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.|||Homohexamer, formed by a dimer of trimers.|||In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.|||In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS03180 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2N8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.|||Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS03585 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2S7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Cell membrane|||In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.|||In the N-terminal section; belongs to the 2-acyl-GPE acetyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1. http://togogenome.org/gene/568768:Dpoa569_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1M0 ^@ Similarity ^@ Belongs to the SlyX family. http://togogenome.org/gene/568768:Dpoa569_RS01605 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04050 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7D8 ^@ Function|||Similarity ^@ Belongs to the precorrin methyltransferase family.|||In the C-terminal section; belongs to the precorrin methyltransferase family.|||In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.|||Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. http://togogenome.org/gene/568768:Dpoa569_RS13655 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8Z1 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/568768:Dpoa569_RS13885 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7Q9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6Q1 ^@ Similarity ^@ Belongs to the SIP oxidoreductase family. http://togogenome.org/gene/568768:Dpoa569_RS07455 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6X7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/568768:Dpoa569_RS13060 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system. http://togogenome.org/gene/568768:Dpoa569_RS05610 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJJ0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/568768:Dpoa569_RS18655 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAV8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS00040 ^@ http://purl.uniprot.org/uniprot/A0A5B8HUL1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS12610 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPQ0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/568768:Dpoa569_RS09170 ^@ http://purl.uniprot.org/uniprot/A0A5B8ILH9 ^@ Similarity ^@ Belongs to the UPF0181 family. http://togogenome.org/gene/568768:Dpoa569_RS01180 ^@ http://purl.uniprot.org/uniprot/A0A5B8IL07 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudC subfamily.|||Binds 1 zinc ion per subunit.|||Divalent metal cations. Mg(2+) or Mn(2+).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates. http://togogenome.org/gene/568768:Dpoa569_RS08140 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5M8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS11290 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7V1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS09855 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6L2 ^@ Similarity ^@ Belongs to the UPF0263 family. http://togogenome.org/gene/568768:Dpoa569_RS18150 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZapG family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS02480 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6B9 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS05820 ^@ http://purl.uniprot.org/uniprot/A0A5B8I615 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4 family.|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS03590 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0X8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.|||Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS03635 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Monomer.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/568768:Dpoa569_RS16425 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/568768:Dpoa569_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3J2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/568768:Dpoa569_RS16680 ^@ http://purl.uniprot.org/uniprot/A0A5B8ILV6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/568768:Dpoa569_RS16560 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS02165 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZV9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/568768:Dpoa569_RS16210 ^@ http://purl.uniprot.org/uniprot/A0A5B8I987 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS08625 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5V3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/568768:Dpoa569_RS16730 ^@ http://purl.uniprot.org/uniprot/A0A5B8IIC5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RlmG family.|||Cytoplasm|||Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS04450 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.|||Cytoplasm|||Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). http://togogenome.org/gene/568768:Dpoa569_RS09585 ^@ http://purl.uniprot.org/uniprot/A0A5B8ILG1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS18805 ^@ http://purl.uniprot.org/uniprot/A0A5B8IKB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS03005 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFI2 ^@ Similarity|||Subunit ^@ Belongs to the beta-eliminating lyase family.|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS02195 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1T4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/568768:Dpoa569_RS04315 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7Y7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS03115 ^@ http://purl.uniprot.org/uniprot/A0A5B8HH24 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). http://togogenome.org/gene/568768:Dpoa569_RS11590 ^@ http://purl.uniprot.org/uniprot/A0A5B8HP06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS03905 ^@ http://purl.uniprot.org/uniprot/A0A5B8I362 ^@ Cofactor|||Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ A single active site specifically recognizes both ATP and CTP and is responsible for their addition.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.|||Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.|||Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.|||Magnesium is required for nucleotidyltransferase activity.|||Monomer. Can also form homodimers and oligomers.|||Nickel for phosphatase activity. http://togogenome.org/gene/568768:Dpoa569_RS07655 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIT1 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/568768:Dpoa569_RS10700 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNF5 ^@ Similarity|||Subunit ^@ Belongs to the glutaredoxin family.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS00510 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0D2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS08395 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7K0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS04120 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIH8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RcsF family.|||Cell outer membrane|||Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects. http://togogenome.org/gene/568768:Dpoa569_RS18310 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICF3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/568768:Dpoa569_RS16545 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICW7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/568768:Dpoa569_RS18810 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICB4 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/568768:Dpoa569_RS09415 ^@ http://purl.uniprot.org/uniprot/A0A5B8HK06 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/568768:Dpoa569_RS18065 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LpoA family.|||Interacts with PBP1a.|||Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). http://togogenome.org/gene/568768:Dpoa569_RS05695 ^@ http://purl.uniprot.org/uniprot/A0A5B8I419 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/568768:Dpoa569_RS05940 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAD9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhE family.|||Cytoplasm|||Necessary for formate dehydrogenase activity. http://togogenome.org/gene/568768:Dpoa569_RS12615 ^@ http://purl.uniprot.org/uniprot/A0A5B8IF54 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/568768:Dpoa569_RS05345 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGZ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP M family.|||Cell inner membrane|||Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS08530 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJH3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04645 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS02865 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2E9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/568768:Dpoa569_RS18260 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRK1 ^@ Similarity ^@ Belongs to the UPF0307 family. http://togogenome.org/gene/568768:Dpoa569_RS17890 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBD0 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/568768:Dpoa569_RS19360 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBB1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArnF family.|||Cell inner membrane|||Heterodimer of ArnE and ArnF.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane. http://togogenome.org/gene/568768:Dpoa569_RS18205 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBL2 ^@ Similarity|||Subunit ^@ Belongs to the SIS family. GutQ/KpsF subfamily.|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS04735 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3K6 ^@ Similarity ^@ Belongs to the YfgM family. http://togogenome.org/gene/568768:Dpoa569_RS08045 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJ43 ^@ Function|||Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.|||Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis. http://togogenome.org/gene/568768:Dpoa569_RS05080 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGS4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS17530 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSD1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/568768:Dpoa569_RS00760 ^@ http://purl.uniprot.org/uniprot/A0A5B8HF58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS02050 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6J3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/568768:Dpoa569_RS10540 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBZ3 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/568768:Dpoa569_RS06260 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJJ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS12140 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18060 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRF7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS07375 ^@ http://purl.uniprot.org/uniprot/A0A5B8I510 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. OpgH subfamily.|||Cell inner membrane|||Cell membrane|||Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS06925 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9H3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/568768:Dpoa569_RS03965 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7Q7 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.|||Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily. http://togogenome.org/gene/568768:Dpoa569_RS02605 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/568768:Dpoa569_RS09590 ^@ http://purl.uniprot.org/uniprot/A0A5B8HK49 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/568768:Dpoa569_RS02920 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHE8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/568768:Dpoa569_RS12070 ^@ http://purl.uniprot.org/uniprot/A0A5B8I819 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS17950 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTI7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Cell membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/568768:Dpoa569_RS17730 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS05685 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2H0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS14125 ^@ http://purl.uniprot.org/uniprot/A0A5B8HP28 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/568768:Dpoa569_RS00580 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0K3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AcsB/BcsB family.|||Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).|||Cell inner membrane|||Tightly associated with the cellulose synthase catalytic subunit. http://togogenome.org/gene/568768:Dpoa569_RS07070 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9K6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CheZ family.|||Cytoplasm|||Homodimer.|||Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). http://togogenome.org/gene/568768:Dpoa569_RS02565 ^@ http://purl.uniprot.org/uniprot/A0A5B8I230 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/568768:Dpoa569_RS18635 ^@ http://purl.uniprot.org/uniprot/A0A5B8HT07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/568768:Dpoa569_RS09525 ^@ http://purl.uniprot.org/uniprot/A0A5B8HK38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS19140 ^@ http://purl.uniprot.org/uniprot/A0A5B8IB61 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18385 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE27 ^@ Function|||Similarity|||Subunit ^@ Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.|||Belongs to the transcriptional regulatory Fis family.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5E8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M4 family.|||Extracellular zinc metalloprotease.|||Secreted http://togogenome.org/gene/568768:Dpoa569_RS03370 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2M2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS15730 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICC6 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS05120 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3U4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS14905 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA76 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/568768:Dpoa569_RS02150 ^@ http://purl.uniprot.org/uniprot/A0A5B8HER6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/568768:Dpoa569_RS09000 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICM2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/568768:Dpoa569_RS12355 ^@ http://purl.uniprot.org/uniprot/A0A5B8HML4 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/568768:Dpoa569_RS11930 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9W4 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/568768:Dpoa569_RS13420 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFW3 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/568768:Dpoa569_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A5B8HI07 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/568768:Dpoa569_RS02780 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0B2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/568768:Dpoa569_RS01340 ^@ http://purl.uniprot.org/uniprot/A0A5B8I145 ^@ Function|||Similarity ^@ In the C-terminal section; belongs to the aldehyde dehydrogenase family.|||In the N-terminal section; belongs to the proline dehydrogenase family.|||Oxidizes proline to glutamate for use as a carbon and nitrogen source. http://togogenome.org/gene/568768:Dpoa569_RS11285 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID29 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS04925 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5I9 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/568768:Dpoa569_RS16630 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS02415 ^@ http://purl.uniprot.org/uniprot/A0A5B8HF20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16185 ^@ http://purl.uniprot.org/uniprot/A0A5B8IHW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Cell inner membrane|||Membrane|||Transports acetate. http://togogenome.org/gene/568768:Dpoa569_RS05900 ^@ http://purl.uniprot.org/uniprot/A0A5B8I470 ^@ Function|||Similarity ^@ Belongs to the carbamoyltransferase HypF family.|||Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. http://togogenome.org/gene/568768:Dpoa569_RS16750 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAQ8 ^@ Similarity ^@ Belongs to the mannitol dehydrogenase family. UxaB subfamily. http://togogenome.org/gene/568768:Dpoa569_RS17340 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDD7 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/568768:Dpoa569_RS07600 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS00660 ^@ http://purl.uniprot.org/uniprot/A0A5B8HF37 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. RsmD family.|||Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle. http://togogenome.org/gene/568768:Dpoa569_RS11715 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6B0 ^@ Similarity ^@ Belongs to the IucA/IucC family. http://togogenome.org/gene/568768:Dpoa569_RS16380 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRS7 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/568768:Dpoa569_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A5B8HL25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS03875 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2V1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS09770 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBF5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the anthranilate synthase component I family.|||Binds 1 Mg(2+) ion per subunit.|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/568768:Dpoa569_RS00540 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS17205 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAY8 ^@ Similarity ^@ Belongs to the Smp family. http://togogenome.org/gene/568768:Dpoa569_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA13 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-90 and Arg-93) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form. http://togogenome.org/gene/568768:Dpoa569_RS13055 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPY0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm|||The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/568768:Dpoa569_RS09960 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKF6 ^@ Cofactor|||Similarity ^@ Belongs to the nitroreductase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/568768:Dpoa569_RS01720 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6C0 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/568768:Dpoa569_RS17360 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBD3 ^@ Function|||Similarity ^@ Belongs to the vsr family.|||May nick specific sequences that contain T:G mispairs resulting from m5C-deamination. http://togogenome.org/gene/568768:Dpoa569_RS15300 ^@ http://purl.uniprot.org/uniprot/A0A5B8HR87 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/568768:Dpoa569_RS10445 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN64 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.|||In the N-terminal section; belongs to the histidinol-phosphatase family. http://togogenome.org/gene/568768:Dpoa569_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A5B8I074 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/568768:Dpoa569_RS03765 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2X3 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/568768:Dpoa569_RS11275 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7J9 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily.|||Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. http://togogenome.org/gene/568768:Dpoa569_RS11260 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9H6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/568768:Dpoa569_RS02770 ^@ http://purl.uniprot.org/uniprot/A0A5B8I709 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/568768:Dpoa569_RS11755 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9T0 ^@ Caution|||Function|||Similarity ^@ Belongs to the ribose 1,5-bisphosphokinase family.|||Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS00045 ^@ http://purl.uniprot.org/uniprot/A0A5B8IKT3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family. RNase BN subfamily.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities. http://togogenome.org/gene/568768:Dpoa569_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A5B8I464 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS12265 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID67 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/568768:Dpoa569_RS12595 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS05645 ^@ http://purl.uniprot.org/uniprot/A0A5B8I408 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS17295 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS01350 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0Y2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. UvrD subfamily.|||Homodimer.|||Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. http://togogenome.org/gene/568768:Dpoa569_RS03065 ^@ http://purl.uniprot.org/uniprot/A0A5B8HH12 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AlaE exporter family.|||Cell inner membrane|||Exports L-alanine. http://togogenome.org/gene/568768:Dpoa569_RS09615 ^@ http://purl.uniprot.org/uniprot/A0A5B8HU28 ^@ Cofactor|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/568768:Dpoa569_RS00380 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0A3 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/568768:Dpoa569_RS07115 ^@ http://purl.uniprot.org/uniprot/A0A5B8HK07 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/568768:Dpoa569_RS02045 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DsrH/TusB family.|||Cytoplasm|||Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. http://togogenome.org/gene/568768:Dpoa569_RS14890 ^@ http://purl.uniprot.org/uniprot/A0A5B8IGX8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/568768:Dpoa569_RS09965 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMS8 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/568768:Dpoa569_RS04465 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1J4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.|||Belongs to the RseA family.|||Cell inner membrane|||Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB. http://togogenome.org/gene/568768:Dpoa569_RS00890 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0L2 ^@ Similarity ^@ Belongs to the agmatine deiminase family. http://togogenome.org/gene/568768:Dpoa569_RS15615 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFF8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6Y9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS01295 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZ70 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/568768:Dpoa569_RS16845 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAY1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiC family.|||Cytoplasm|||Monomer.|||Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. http://togogenome.org/gene/568768:Dpoa569_RS02700 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6H2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS18325 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/568768:Dpoa569_RS05330 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2A4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP J family.|||Cell inner membrane|||Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS09335 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICU5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJ48 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/568768:Dpoa569_RS05315 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJC3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GSP G family.|||Cell inner membrane|||Membrane|||Type II secretion system is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. Forms homomultimers. http://togogenome.org/gene/568768:Dpoa569_RS03135 ^@ http://purl.uniprot.org/uniprot/A0A5B8I792 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/568768:Dpoa569_RS13195 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ87 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/568768:Dpoa569_RS15640 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8Y3 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/568768:Dpoa569_RS03975 ^@ http://purl.uniprot.org/uniprot/A0A5B8I190 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.|||Homohexamer; trimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS17255 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBN6 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/568768:Dpoa569_RS15180 ^@ http://purl.uniprot.org/uniprot/A0A5B8IH60 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS08235 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7H7 ^@ Similarity ^@ Belongs to the peptidase S1B family. http://togogenome.org/gene/568768:Dpoa569_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Fes family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS05020 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS01065 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS02325 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEV4 ^@ Similarity ^@ Belongs to the malate synthase family. http://togogenome.org/gene/568768:Dpoa569_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A5B8HLA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS09885 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS08910 ^@ http://purl.uniprot.org/uniprot/A0A5B8IF70 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit.|||Cleaves the N-terminal amino acid of tripeptides.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS11830 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEK2 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ 4-aminobutanal can spontaneously cyclize to 1-pyrroline, and 5-aminopentanal to 1-piperideine.|||Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.|||Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS13220 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS07630 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5A5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.|||Cell membrane|||Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF). http://togogenome.org/gene/568768:Dpoa569_RS16735 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS11860 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7U5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS13845 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNV4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/568768:Dpoa569_RS11610 ^@ http://purl.uniprot.org/uniprot/A0A5B8I824 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6.|||Represents a citryl-ACP lyase. http://togogenome.org/gene/568768:Dpoa569_RS04665 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIU3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 2 iron ions per dimer. The dimer may bind additional iron ions.|||Homodimer; may form tetramers and higher multimers.|||Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. http://togogenome.org/gene/568768:Dpoa569_RS08230 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAE3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell inner membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/568768:Dpoa569_RS09905 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/568768:Dpoa569_RS03705 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2V6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/568768:Dpoa569_RS00030 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmJ family.|||Cytoplasm|||Specifically methylates the guanosine in position 1516 of 16S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS13820 ^@ http://purl.uniprot.org/uniprot/A0A5B8IG73 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJ00 ^@ Similarity ^@ Belongs to the UPF0115 family. http://togogenome.org/gene/568768:Dpoa569_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A5B8I826 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/568768:Dpoa569_RS05010 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3Q6 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/568768:Dpoa569_RS03090 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2F0 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS02835 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0C7 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/568768:Dpoa569_RS18225 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDY3 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/568768:Dpoa569_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/568768:Dpoa569_RS07830 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YkuD family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS00620 ^@ http://purl.uniprot.org/uniprot/A0A5B8HDS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS10335 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8V4 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/568768:Dpoa569_RS06910 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4V0 ^@ Similarity ^@ Belongs to the phage portal family. PBSX subfamily. http://togogenome.org/gene/568768:Dpoa569_RS15440 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAI7 ^@ Similarity ^@ Belongs to the MipA/OmpV family. http://togogenome.org/gene/568768:Dpoa569_RS03390 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/568768:Dpoa569_RS01135 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5L0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/568768:Dpoa569_RS14930 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBU6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.|||Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).|||Binds 1 Mg(2+) ion per subunit.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS12980 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8I8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcA family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||nucleolus http://togogenome.org/gene/568768:Dpoa569_RS09130 ^@ http://purl.uniprot.org/uniprot/A0A5B8I635 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS17935 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC20 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the rhamnose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the interconversion of L-rhamnose and L-rhamnulose.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS02430 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1Z5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS01655 ^@ http://purl.uniprot.org/uniprot/A0A5B8I158 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS04085 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1C0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/568768:Dpoa569_RS05625 ^@ http://purl.uniprot.org/uniprot/A0A5B8I453 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.|||Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS18350 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/568768:Dpoa569_RS16520 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAM1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase U32 family. UbiV subfamily.|||Forms an heterodimer with UbiU.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway. http://togogenome.org/gene/568768:Dpoa569_RS03560 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHC9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/568768:Dpoa569_RS19010 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEG3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.|||Cell membrane|||Efflux system for nickel and cobalt.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10140 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6T3 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/568768:Dpoa569_RS02615 ^@ http://purl.uniprot.org/uniprot/A0A5B8I241 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SprT family.|||Binds 1 zinc ion.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS05790 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2J7 ^@ Similarity|||Subunit ^@ Belongs to the complex I 75 kDa subunit family.|||Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex. http://togogenome.org/gene/568768:Dpoa569_RS19395 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTH2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/568768:Dpoa569_RS11350 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7W5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion.|||Homodimer.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/568768:Dpoa569_RS05270 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8I9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18370 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS09340 ^@ http://purl.uniprot.org/uniprot/A0A5B8I699 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolB family.|||Cell outer membrane|||Membrane|||Monomer.|||Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. http://togogenome.org/gene/568768:Dpoa569_RS04875 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5H6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.|||Cell outer membrane|||Membrane|||Monomer and homodimer.|||The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.|||With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. http://togogenome.org/gene/568768:Dpoa569_RS10095 ^@ http://purl.uniprot.org/uniprot/A0A5B8I596 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M23B family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07155 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4V8 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Secreted http://togogenome.org/gene/568768:Dpoa569_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6E5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IgaA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS13365 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS03200 ^@ http://purl.uniprot.org/uniprot/A0A5B8IL06 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/568768:Dpoa569_RS19080 ^@ http://purl.uniprot.org/uniprot/A0A5B8IKJ6 ^@ Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Homodimer.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A5B8HH42 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapD family.|||Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.|||Cytoplasm|||Interacts with FtsZ. http://togogenome.org/gene/568768:Dpoa569_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6K2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/568768:Dpoa569_RS07955 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7B7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the pyridoxine kinase family. PdxY subfamily.|||Homodimer.|||Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. http://togogenome.org/gene/568768:Dpoa569_RS18295 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBZ8 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/568768:Dpoa569_RS18470 ^@ http://purl.uniprot.org/uniprot/A0A5B8ILZ4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.|||Binds 2 manganese ions per subunit.|||Splits dipeptides with a prolyl residue in the C-terminal position. http://togogenome.org/gene/568768:Dpoa569_RS14050 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7U9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS17740 ^@ http://purl.uniprot.org/uniprot/A0A5B8HR92 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/568768:Dpoa569_RS16245 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSF6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/568768:Dpoa569_RS16765 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSS3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS01485 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15155 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPR9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/568768:Dpoa569_RS11725 ^@ http://purl.uniprot.org/uniprot/A0A5B8I854 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/568768:Dpoa569_RS12720 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8K1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SeqA family.|||Cytoplasm|||Homodimer. Polymerizes to form helical filaments.|||Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. http://togogenome.org/gene/568768:Dpoa569_RS00300 ^@ http://purl.uniprot.org/uniprot/A0A5B8HDK1 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/568768:Dpoa569_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2C5 ^@ Similarity|||Subunit ^@ Homotetramer.|||In the C-terminal section; belongs to the homoserine dehydrogenase family.|||In the N-terminal section; belongs to the aspartokinase family. http://togogenome.org/gene/568768:Dpoa569_RS18515 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRQ8 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/568768:Dpoa569_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1R9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS10305 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5E4 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.|||Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs. http://togogenome.org/gene/568768:Dpoa569_RS00440 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0B3 ^@ Function|||Similarity ^@ Belongs to the mannonate dehydratase family.|||Catalyzes the dehydration of D-mannonate. http://togogenome.org/gene/568768:Dpoa569_RS11810 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9U2 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/568768:Dpoa569_RS01890 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1I5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.|||Monomer.|||Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. http://togogenome.org/gene/568768:Dpoa569_RS02985 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0G8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane|||The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB). http://togogenome.org/gene/568768:Dpoa569_RS19245 ^@ http://purl.uniprot.org/uniprot/A0A5B8IKQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15075 ^@ http://purl.uniprot.org/uniprot/A0A5B8IF12 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS18575 ^@ http://purl.uniprot.org/uniprot/A0A5B8IK05 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M20A family. ArgE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS00095 ^@ http://purl.uniprot.org/uniprot/A0A5B8IKV1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS01545 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5T2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.|||FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands. http://togogenome.org/gene/568768:Dpoa569_RS05065 ^@ http://purl.uniprot.org/uniprot/A0A5B8I243 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS05605 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5X3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.|||Cytoplasm|||In the C-terminal section; belongs to the DAO family.|||In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. http://togogenome.org/gene/568768:Dpoa569_RS19330 ^@ http://purl.uniprot.org/uniprot/A0A5B8HUH9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.|||Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS18680 ^@ http://purl.uniprot.org/uniprot/A0A5B8IK39 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS15070 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRR6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/568768:Dpoa569_RS07100 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4Z7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FlgA family.|||Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS04655 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7T0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/568768:Dpoa569_RS07165 ^@ http://purl.uniprot.org/uniprot/A0A5B8HK63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/568768:Dpoa569_RS04140 ^@ http://purl.uniprot.org/uniprot/A0A5B8I374 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS10850 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7C0 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS09830 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TonB family.|||Cell inner membrane|||Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/568768:Dpoa569_RS15355 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRA0 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS17960 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJF7 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/568768:Dpoa569_RS00430 ^@ http://purl.uniprot.org/uniprot/A0A5B8HYJ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS13835 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9K9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/568768:Dpoa569_RS14700 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQX5 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS12210 ^@ http://purl.uniprot.org/uniprot/A0A5B8HV56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS11420 ^@ http://purl.uniprot.org/uniprot/A0A5B8HLV7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS01220 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0U4 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/568768:Dpoa569_RS07730 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKU9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS07415 ^@ http://purl.uniprot.org/uniprot/A0A5B8I562 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS07150 ^@ http://purl.uniprot.org/uniprot/A0A5B8I512 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/568768:Dpoa569_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS03495 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2K4 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/568768:Dpoa569_RS14895 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9W2 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/568768:Dpoa569_RS12560 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPN8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/568768:Dpoa569_RS07125 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/568768:Dpoa569_RS02555 ^@ http://purl.uniprot.org/uniprot/A0A5B8HF11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/568768:Dpoa569_RS13435 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9D4 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/568768:Dpoa569_RS13530 ^@ http://purl.uniprot.org/uniprot/A0A5B8I959 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/568768:Dpoa569_RS12945 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDL3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/568768:Dpoa569_RS09385 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMC0 ^@ Function|||Similarity ^@ Belongs to the AlaDH/PNT family.|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/568768:Dpoa569_RS12885 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ09 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/568768:Dpoa569_RS16855 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBE4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/568768:Dpoa569_RS12985 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN42 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0756 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS15215 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRU1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/568768:Dpoa569_RS18615 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LysR transcriptional regulatory family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS15965 ^@ http://purl.uniprot.org/uniprot/A0A5B8IHV0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/568768:Dpoa569_RS09350 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6F0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/568768:Dpoa569_RS08165 ^@ http://purl.uniprot.org/uniprot/A0A5B8HL26 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TtcA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.|||Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.|||Cytoplasm|||Homodimer.|||The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster. http://togogenome.org/gene/568768:Dpoa569_RS13470 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFX9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15220 ^@ http://purl.uniprot.org/uniprot/A0A5B8IF42 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/568768:Dpoa569_RS09720 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBE5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/568768:Dpoa569_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A5B8HE45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS11370 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICK2 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/568768:Dpoa569_RS17170 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDA2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the P-Pant transferase superfamily. EntD family.|||EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.|||Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively. http://togogenome.org/gene/568768:Dpoa569_RS10645 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS05035 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIL4 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/568768:Dpoa569_RS10255 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5D2 ^@ Similarity ^@ Belongs to the RNase T2 family. http://togogenome.org/gene/568768:Dpoa569_RS00665 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5A4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/568768:Dpoa569_RS12175 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6L1 ^@ Function|||Similarity ^@ Belongs to the EfeM/EfeO family.|||Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component. http://togogenome.org/gene/568768:Dpoa569_RS15235 ^@ http://purl.uniprot.org/uniprot/A0A5B8IH78 ^@ Similarity ^@ Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. http://togogenome.org/gene/568768:Dpoa569_RS02075 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1L0 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/568768:Dpoa569_RS02275 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1S4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). http://togogenome.org/gene/568768:Dpoa569_RS12075 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6I1 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the peroxidase family. Peroxidase/catalase subfamily.|||Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.|||Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS17455 ^@ http://purl.uniprot.org/uniprot/A0A5B8HT74 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/568768:Dpoa569_RS07105 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4U3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/568768:Dpoa569_RS04460 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3D2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/568768:Dpoa569_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1Y7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FrdC family.|||Cell membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. http://togogenome.org/gene/568768:Dpoa569_RS01650 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5V1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS01860 ^@ http://purl.uniprot.org/uniprot/A0A5B8HG20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18550 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAT8 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/568768:Dpoa569_RS05985 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8X4 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. http://togogenome.org/gene/568768:Dpoa569_RS04610 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIS7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A5B8I762 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/568768:Dpoa569_RS15700 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8Z3 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS16165 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04360 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIM4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/568768:Dpoa569_RS16755 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQP4 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/568768:Dpoa569_RS00595 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0E8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 8 (cellulase D) family. http://togogenome.org/gene/568768:Dpoa569_RS06060 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJU1 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS09450 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS18745 ^@ http://purl.uniprot.org/uniprot/A0A5B8HT28 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/568768:Dpoa569_RS08635 ^@ http://purl.uniprot.org/uniprot/A0A5B8HLK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS15035 ^@ http://purl.uniprot.org/uniprot/A0A5B8HR41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10455 ^@ http://purl.uniprot.org/uniprot/A0A5B8I749 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS10070 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBN1 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS00170 ^@ http://purl.uniprot.org/uniprot/A0A5B8I048 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/568768:Dpoa569_RS07720 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein SsuA/TauA family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS10360 ^@ http://purl.uniprot.org/uniprot/A0A5B8I778 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS07300 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBC8 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS18005 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/568768:Dpoa569_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A5B8I205 ^@ Function|||Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.|||Catalyzes the biosynthesis of agmatine from arginine. http://togogenome.org/gene/568768:Dpoa569_RS02115 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/568768:Dpoa569_RS09665 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBD2 ^@ Similarity ^@ Belongs to the ribulokinase family. http://togogenome.org/gene/568768:Dpoa569_RS03130 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/568768:Dpoa569_RS13850 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQU8 ^@ Similarity ^@ Belongs to the skp family. http://togogenome.org/gene/568768:Dpoa569_RS00265 ^@ http://purl.uniprot.org/uniprot/A0A5B8HYD7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/568768:Dpoa569_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0P1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MetJ family.|||Cytoplasm|||Does not bind DNA by a helix-turn-helix motif.|||Homodimer.|||This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. http://togogenome.org/gene/568768:Dpoa569_RS03035 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2E1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS13840 ^@ http://purl.uniprot.org/uniprot/A0A5B8I921 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/568768:Dpoa569_RS09110 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICP8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS11380 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNU7 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/568768:Dpoa569_RS04195 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4Y4 ^@ Function|||Subunit ^@ DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.|||The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau. http://togogenome.org/gene/568768:Dpoa569_RS10855 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5R4 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/568768:Dpoa569_RS10675 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5N7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/568768:Dpoa569_RS13140 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ72 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS11090 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS01465 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZB3 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/568768:Dpoa569_RS14955 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA87 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/568768:Dpoa569_RS14865 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPK4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Crl family.|||Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS16250 ^@ http://purl.uniprot.org/uniprot/A0A5B8IHX7 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/568768:Dpoa569_RS13190 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNA8 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/568768:Dpoa569_RS13185 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8N1 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/568768:Dpoa569_RS02495 ^@ http://purl.uniprot.org/uniprot/A0A5B8IL25 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/568768:Dpoa569_RS11890 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS15280 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPT0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/568768:Dpoa569_RS03680 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.|||Cytoplasm|||Homodimer.|||Specifically methylates the ribose of guanosine 2251 in 23S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS18770 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICR7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS04130 ^@ http://purl.uniprot.org/uniprot/A0A5B8I361 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5J9 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/568768:Dpoa569_RS05320 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP H family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS00080 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICH2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/568768:Dpoa569_RS07035 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4Y7 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/568768:Dpoa569_RS18095 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAL2 ^@ Function|||Similarity ^@ Belongs to the peptidase C56 family.|||Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate. http://togogenome.org/gene/568768:Dpoa569_RS03695 ^@ http://purl.uniprot.org/uniprot/A0A5B8HI29 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS17840 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBC1 ^@ Similarity ^@ Belongs to the UPF0306 family. http://togogenome.org/gene/568768:Dpoa569_RS08685 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5W7 ^@ Function|||Similarity ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). http://togogenome.org/gene/568768:Dpoa569_RS08130 ^@ http://purl.uniprot.org/uniprot/A0A5B8HL57 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase S45 family.|||Binds 1 Ca(2+) ion per dimer. http://togogenome.org/gene/568768:Dpoa569_RS19300 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS14505 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9D8 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS13635 ^@ http://purl.uniprot.org/uniprot/A0A5B8IG31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/568768:Dpoa569_RS09925 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMR4 ^@ Similarity ^@ Belongs to the UPF0225 family. http://togogenome.org/gene/568768:Dpoa569_RS01905 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1D1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/568768:Dpoa569_RS11120 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5X6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.|||Binds 1 [4Fe-4S] cluster.|||DNA-dependent ATPase and 5'-3' DNA helicase. http://togogenome.org/gene/568768:Dpoa569_RS01170 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0T2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/568768:Dpoa569_RS11680 ^@ http://purl.uniprot.org/uniprot/A0A5B8HM43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16350 ^@ http://purl.uniprot.org/uniprot/A0A5B8IB37 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS03460 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6Z7 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/568768:Dpoa569_RS13585 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7H3 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/568768:Dpoa569_RS11220 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7J3 ^@ Similarity|||Subunit ^@ Belongs to the MoaE family.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/568768:Dpoa569_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5V2 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/568768:Dpoa569_RS03315 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0Q4 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/568768:Dpoa569_RS15900 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICG9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GSP G family.|||Cell inner membrane|||Membrane|||Type II secretion system is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. Forms homomultimers. http://togogenome.org/gene/568768:Dpoa569_RS01800 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEM4 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS17760 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSH8 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/568768:Dpoa569_RS13520 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ80 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). http://togogenome.org/gene/568768:Dpoa569_RS16985 ^@ http://purl.uniprot.org/uniprot/A0A5B8IIL9 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/568768:Dpoa569_RS13110 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFN7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/568768:Dpoa569_RS16670 ^@ http://purl.uniprot.org/uniprot/A0A5B8IIB1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LDH/MDH superfamily. MDH type 1 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS16105 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS11980 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9X7 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 2 family.|||Binds 1 sodium ion per monomer.|||Binds 2 magnesium ions per monomer.|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS09440 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMD6 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/568768:Dpoa569_RS15915 ^@ http://purl.uniprot.org/uniprot/A0A5B8IHT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family. GSP D subfamily.|||Cell outer membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10860 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7H8 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport. http://togogenome.org/gene/568768:Dpoa569_RS12860 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15670 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICA6 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/568768:Dpoa569_RS09910 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMR6 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/568768:Dpoa569_RS04595 ^@ http://purl.uniprot.org/uniprot/A0A5B8HI75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Secreted http://togogenome.org/gene/568768:Dpoa569_RS02240 ^@ http://purl.uniprot.org/uniprot/A0A5B8I680 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS09560 ^@ http://purl.uniprot.org/uniprot/A0A5B8HV18 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/568768:Dpoa569_RS18555 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICL6 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/568768:Dpoa569_RS03780 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHJ9 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/568768:Dpoa569_RS05560 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS12370 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA58 ^@ Similarity ^@ Belongs to the UPF0053 family. http://togogenome.org/gene/568768:Dpoa569_RS00625 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. YhhS family.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS12570 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8F9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/568768:Dpoa569_RS18760 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC98 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/568768:Dpoa569_RS13040 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS11630 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICR4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS12820 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBX9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS10395 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CitD family.|||Covalent carrier of the coenzyme of citrate lyase.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6. http://togogenome.org/gene/568768:Dpoa569_RS05550 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5V9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/568768:Dpoa569_RS04845 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1U8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS00035 ^@ http://purl.uniprot.org/uniprot/A0A5B8HS88 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/568768:Dpoa569_RS07620 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF). http://togogenome.org/gene/568768:Dpoa569_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TPS (TC 1.B.20) family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS02330 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6R1 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/568768:Dpoa569_RS16510 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9D9 ^@ Function|||Similarity ^@ Belongs to the UbiT family.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor. http://togogenome.org/gene/568768:Dpoa569_RS01110 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZ29 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NusG family.|||Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.|||Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination. http://togogenome.org/gene/568768:Dpoa569_RS14605 ^@ http://purl.uniprot.org/uniprot/A0A5B8IGQ1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/568768:Dpoa569_RS11180 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7S5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07970 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5J2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS11800 ^@ http://purl.uniprot.org/uniprot/A0A5B8HP78 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/568768:Dpoa569_RS09820 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBH3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YciB family.|||Cell inner membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. http://togogenome.org/gene/568768:Dpoa569_RS00630 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0L8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcrB family.|||Cell membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered. http://togogenome.org/gene/568768:Dpoa569_RS12910 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8R8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RlpA family.|||Cell membrane|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/568768:Dpoa569_RS04075 ^@ http://purl.uniprot.org/uniprot/A0A5B8I349 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsB family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/568768:Dpoa569_RS08145 ^@ http://purl.uniprot.org/uniprot/A0A5B8I433 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/568768:Dpoa569_RS12380 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEZ7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS12620 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8G9 ^@ Function|||Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/568768:Dpoa569_RS02720 ^@ http://purl.uniprot.org/uniprot/A0A5B8I270 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TrpR family.|||Cytoplasm|||Homodimer.|||This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. http://togogenome.org/gene/568768:Dpoa569_RS04500 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIQ3 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/568768:Dpoa569_RS04365 ^@ http://purl.uniprot.org/uniprot/A0A5B8I802 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/568768:Dpoa569_RS02775 ^@ http://purl.uniprot.org/uniprot/A0A5B8I283 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/568768:Dpoa569_RS15620 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiK family.|||Cytoplasm|||Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both. http://togogenome.org/gene/568768:Dpoa569_RS04415 ^@ http://purl.uniprot.org/uniprot/A0A5B8I369 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS10205 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6X9 ^@ Similarity ^@ Belongs to the UPF0502 family. http://togogenome.org/gene/568768:Dpoa569_RS15210 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPS5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/568768:Dpoa569_RS10865 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Set transporter family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04640 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSF3 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/568768:Dpoa569_RS18785 ^@ http://purl.uniprot.org/uniprot/A0A5B8HU60 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/568768:Dpoa569_RS09065 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4K3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS02100 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEQ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/568768:Dpoa569_RS01415 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFR4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WzyE family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.|||Probably part of a complex composed of WzxE, WzyE and WzzE. http://togogenome.org/gene/568768:Dpoa569_RS11080 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7F1 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/568768:Dpoa569_RS00615 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0F6 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/568768:Dpoa569_RS02250 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEU3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/568768:Dpoa569_RS04025 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1A5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS18660 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICP5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS07880 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5B0 ^@ Function ^@ Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil. http://togogenome.org/gene/568768:Dpoa569_RS01395 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZ96 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the WecD family.|||Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS18215 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTR5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptC family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.|||Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/568768:Dpoa569_RS01900 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1C8 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily. http://togogenome.org/gene/568768:Dpoa569_RS11225 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5Z7 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/568768:Dpoa569_RS11425 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNY4 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/568768:Dpoa569_RS02260 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1V3 ^@ Similarity ^@ Belongs to the Smg family. http://togogenome.org/gene/568768:Dpoa569_RS05920 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS10110 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS02610 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6X3 ^@ Similarity ^@ Belongs to the EndA/NucM nuclease family. http://togogenome.org/gene/568768:Dpoa569_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8I0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS12315 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID78 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/568768:Dpoa569_RS13510 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE25 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/568768:Dpoa569_RS03520 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS07890 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKV0 ^@ Domain|||Function|||Subunit ^@ Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.|||Homodimer.|||Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. http://togogenome.org/gene/568768:Dpoa569_RS09995 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6P7 ^@ Similarity ^@ Belongs to the glucose-6-phosphate 1-epimerase family. http://togogenome.org/gene/568768:Dpoa569_RS19295 ^@ http://purl.uniprot.org/uniprot/A0A5B8IKS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS08365 ^@ http://purl.uniprot.org/uniprot/A0A5B8I489 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/568768:Dpoa569_RS13505 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/568768:Dpoa569_RS11835 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7W7 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/568768:Dpoa569_RS09880 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS13535 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7G0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers. http://togogenome.org/gene/568768:Dpoa569_RS12195 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPM3 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/568768:Dpoa569_RS12670 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8I2 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase class-1 family.|||Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/568768:Dpoa569_RS10290 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN21 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family. MukB subfamily.|||Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.|||Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.|||The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.|||nucleoid http://togogenome.org/gene/568768:Dpoa569_RS18460 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TrkH potassium transport family.|||Cell inner membrane|||Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS11570 ^@ http://purl.uniprot.org/uniprot/A0A5B8HM00 ^@ Similarity ^@ Belongs to the glycosyl hydrolase. http://togogenome.org/gene/568768:Dpoa569_RS15585 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA99 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/568768:Dpoa569_RS16865 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQS4 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. http://togogenome.org/gene/568768:Dpoa569_RS17185 ^@ http://purl.uniprot.org/uniprot/A0A5B8IIR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0391 family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS05860 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJ89 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.|||Cell membrane|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/568768:Dpoa569_RS15760 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA45 ^@ Similarity ^@ Belongs to the UPF0125 (RnfH) family. http://togogenome.org/gene/568768:Dpoa569_RS19385 ^@ http://purl.uniprot.org/uniprot/A0A5B8IKR9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/568768:Dpoa569_RS02705 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS09675 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMJ2 ^@ Similarity ^@ Belongs to the Hha/YmoA/Cnu family. http://togogenome.org/gene/568768:Dpoa569_RS18625 ^@ http://purl.uniprot.org/uniprot/A0A5B8IK22 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/568768:Dpoa569_RS00780 ^@ http://purl.uniprot.org/uniprot/A0A5B8HDW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS13590 ^@ http://purl.uniprot.org/uniprot/A0A5B8HV72 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS00270 ^@ http://purl.uniprot.org/uniprot/A0A5B8I081 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS01740 ^@ http://purl.uniprot.org/uniprot/A0A5B8I183 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/568768:Dpoa569_RS16610 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRX1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/568768:Dpoa569_RS02845 ^@ http://purl.uniprot.org/uniprot/A0A5B8I259 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/568768:Dpoa569_RS10670 ^@ http://purl.uniprot.org/uniprot/A0A5B8I787 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS03110 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFM0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. FtsW subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Peptidoglycan polymerase that is essential for cell division. http://togogenome.org/gene/568768:Dpoa569_RS15875 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP M family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS00710 ^@ http://purl.uniprot.org/uniprot/A0A5B8HF48 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/568768:Dpoa569_RS15750 ^@ http://purl.uniprot.org/uniprot/A0A5B8I903 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/568768:Dpoa569_RS04510 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3E4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/568768:Dpoa569_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A5B8I526 ^@ Function|||Similarity|||Subunit ^@ A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.|||Belongs to the YihI family.|||Interacts with Der. http://togogenome.org/gene/568768:Dpoa569_RS02065 ^@ http://purl.uniprot.org/uniprot/A0A5B8HE36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/568768:Dpoa569_RS07855 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5G6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/568768:Dpoa569_RS17835 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBZ6 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/568768:Dpoa569_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A5B8I269 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Cell inner membrane|||Involved in succinate export with YjjP. Both proteins are required for export.|||Membrane|||The transporter is composed of YjjB and YjjP. http://togogenome.org/gene/568768:Dpoa569_RS08620 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5Z3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/568768:Dpoa569_RS08265 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5Q7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS05845 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4A1 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/568768:Dpoa569_RS10040 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6Q8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CopD family.|||Cell inner membrane|||Involved in copper resistance.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS08705 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS01730 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZL9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S54 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Rhomboid-type serine protease that catalyzes intramembrane proteolysis. http://togogenome.org/gene/568768:Dpoa569_RS10560 ^@ http://purl.uniprot.org/uniprot/A0A5B8I771 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS14625 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9G3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/568768:Dpoa569_RS09255 ^@ http://purl.uniprot.org/uniprot/A0A5B8HM86 ^@ Function|||Similarity ^@ Belongs to the DadA oxidoreductase family.|||Oxidative deamination of D-amino acids. http://togogenome.org/gene/568768:Dpoa569_RS02085 ^@ http://purl.uniprot.org/uniprot/A0A5B8HG78 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/568768:Dpoa569_RS14875 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEW5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.|||Cell membrane|||Homotetramer.|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine. http://togogenome.org/gene/568768:Dpoa569_RS12875 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8F5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptE lipoprotein family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.|||Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. http://togogenome.org/gene/568768:Dpoa569_RS10895 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A5B8HET1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/568768:Dpoa569_RS10835 ^@ http://purl.uniprot.org/uniprot/A0A5B8ILL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18720 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC57 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/568768:Dpoa569_RS18135 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJQ3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/568768:Dpoa569_RS13325 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7B1 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/568768:Dpoa569_RS16440 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAR2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS13605 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8X9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Periplasm|||Secreted http://togogenome.org/gene/568768:Dpoa569_RS02400 ^@ http://purl.uniprot.org/uniprot/A0A5B8I022 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/568768:Dpoa569_RS18090 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBU4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/568768:Dpoa569_RS05710 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8N4 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/568768:Dpoa569_RS08190 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC17 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS18570 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTZ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS09945 ^@ http://purl.uniprot.org/uniprot/A0A5B8I564 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/568768:Dpoa569_RS02160 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1S1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/568768:Dpoa569_RS01955 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1J9 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/568768:Dpoa569_RS18935 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC31 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/568768:Dpoa569_RS04535 ^@ http://purl.uniprot.org/uniprot/A0A5B8HI60 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS18380 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJS5 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusB subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/568768:Dpoa569_RS16720 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS18200 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS12485 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8E3 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/568768:Dpoa569_RS12295 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8I7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS09710 ^@ http://purl.uniprot.org/uniprot/A0A5B8HK71 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/568768:Dpoa569_RS05785 ^@ http://purl.uniprot.org/uniprot/A0A5B8I490 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/568768:Dpoa569_RS18465 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJT3 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/568768:Dpoa569_RS12775 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6Z6 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/568768:Dpoa569_RS00320 ^@ http://purl.uniprot.org/uniprot/A0A5B8I091 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/568768:Dpoa569_RS10490 ^@ http://purl.uniprot.org/uniprot/A0A5B8I930 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS03865 ^@ http://purl.uniprot.org/uniprot/A0A5B8HUQ7 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/568768:Dpoa569_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A5B8HYZ2 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/568768:Dpoa569_RS00220 ^@ http://purl.uniprot.org/uniprot/A0A5B8I069 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.|||Belongs to the SrkA/RdoA protein kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS18160 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRI2 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/568768:Dpoa569_RS15515 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFC3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS07785 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKW3 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/568768:Dpoa569_RS04325 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1H5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 1 iron-sulfur cluster per subunit.|||Homodimer.|||Required for insertion of 4Fe-4S clusters for at least IspG. http://togogenome.org/gene/568768:Dpoa569_RS05800 ^@ http://purl.uniprot.org/uniprot/A0A5B8I447 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/568768:Dpoa569_RS04630 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18100 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC95 ^@ PTM|||Subcellular Location Annotation ^@ Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS17225 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDB5 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/568768:Dpoa569_RS09970 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBK4 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/568768:Dpoa569_RS16205 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS08260 ^@ http://purl.uniprot.org/uniprot/A0A5B8IF55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS01970 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1I2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.|||Cell inner membrane|||Interacts with KefB.|||Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. http://togogenome.org/gene/568768:Dpoa569_RS02090 ^@ http://purl.uniprot.org/uniprot/A0A5B8I636 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/568768:Dpoa569_RS13305 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS12880 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN07 ^@ Similarity ^@ Belongs to the DNA polymerase HolA subunit family. http://togogenome.org/gene/568768:Dpoa569_RS10680 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7E4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/568768:Dpoa569_RS01405 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0Z6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS03030 ^@ http://purl.uniprot.org/uniprot/A0A5B8I774 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS06995 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIA8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 24 family. http://togogenome.org/gene/568768:Dpoa569_RS18425 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16400 ^@ http://purl.uniprot.org/uniprot/A0A5B8IB54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10375 ^@ http://purl.uniprot.org/uniprot/A0A5B8HL11 ^@ Similarity ^@ Belongs to the CitG/MdcB family. http://togogenome.org/gene/568768:Dpoa569_RS03550 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2L9 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/568768:Dpoa569_RS12825 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8E6 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/568768:Dpoa569_RS02890 ^@ http://purl.uniprot.org/uniprot/A0A5B8I276 ^@ Similarity ^@ Belongs to the ThrE exporter (TC 2.A.79) family. http://togogenome.org/gene/568768:Dpoa569_RS04530 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGH4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/568768:Dpoa569_RS12520 ^@ http://purl.uniprot.org/uniprot/A0A5B8HU84 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS07315 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3J0 ^@ Function ^@ Repressor involved in choline regulation of the bet genes.|||Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine. http://togogenome.org/gene/568768:Dpoa569_RS02930 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2B7 ^@ Domain|||Function|||Subcellular Location Annotation ^@ Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.|||Periplasm|||The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition. http://togogenome.org/gene/568768:Dpoa569_RS17155 ^@ http://purl.uniprot.org/uniprot/A0A5B8IIR5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/568768:Dpoa569_RS02695 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGL5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/568768:Dpoa569_RS14935 ^@ http://purl.uniprot.org/uniprot/A0A5B8HR15 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aldolase class II family. MtnB subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). http://togogenome.org/gene/568768:Dpoa569_RS12645 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPW7 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/568768:Dpoa569_RS00695 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0H4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16375 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICT7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS09240 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6C5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DsbB family.|||Cell inner membrane|||Cell membrane|||Membrane|||Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein. http://togogenome.org/gene/568768:Dpoa569_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJ13 ^@ Caution|||Function|||Induction|||PTM|||Similarity|||Subunit ^@ Belongs to the SulA family.|||By DNA damage, as part of the SOS response.|||Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.|||Interacts with FtsZ.|||Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS14640 ^@ http://purl.uniprot.org/uniprot/A0A5B8IES4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS04090 ^@ http://purl.uniprot.org/uniprot/A0A5B8I360 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruD family.|||Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs. http://togogenome.org/gene/568768:Dpoa569_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJ76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Cell inner membrane|||Membrane|||Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake. http://togogenome.org/gene/568768:Dpoa569_RS12440 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6S1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/568768:Dpoa569_RS11815 ^@ http://purl.uniprot.org/uniprot/A0A5B8HP64 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS02205 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6N8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/568768:Dpoa569_RS09455 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS04000 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7C4 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/568768:Dpoa569_RS10390 ^@ http://purl.uniprot.org/uniprot/A0A5B8I824 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6.|||Represents a citryl-ACP lyase. http://togogenome.org/gene/568768:Dpoa569_RS11435 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9L4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS02525 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1U3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family. http://togogenome.org/gene/568768:Dpoa569_RS12285 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8A1 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/568768:Dpoa569_RS02805 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGT1 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/568768:Dpoa569_RS04675 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3H8 ^@ Function|||Similarity ^@ Belongs to the heat shock protein 70 family.|||Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. http://togogenome.org/gene/568768:Dpoa569_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1J8 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/568768:Dpoa569_RS09155 ^@ http://purl.uniprot.org/uniprot/A0A5B8HM52 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/568768:Dpoa569_RS10135 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS07490 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIN6 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/568768:Dpoa569_RS01885 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6F7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/568768:Dpoa569_RS03255 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7B8 ^@ Similarity ^@ Belongs to the UPF0231 family. http://togogenome.org/gene/568768:Dpoa569_RS14975 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS11885 ^@ http://purl.uniprot.org/uniprot/A0A5B8HP81 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS10510 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5K5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS15150 ^@ http://purl.uniprot.org/uniprot/A0A5B8HVA4 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/568768:Dpoa569_RS08650 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS12830 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMY9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS11130 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7G3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/568768:Dpoa569_RS09740 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID28 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/568768:Dpoa569_RS12765 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFA8 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/568768:Dpoa569_RS05795 ^@ http://purl.uniprot.org/uniprot/A0A5B8I491 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/568768:Dpoa569_RS13855 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamA family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. http://togogenome.org/gene/568768:Dpoa569_RS07980 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5K0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapA family.|||Cell inner membrane|||Involved in the assembly of lipopolysaccharide (LPS).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS07825 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIX6 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/568768:Dpoa569_RS18730 ^@ http://purl.uniprot.org/uniprot/A0A5B8HU42 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/568768:Dpoa569_RS16130 ^@ http://purl.uniprot.org/uniprot/A0A5B8II00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BexD/CtrA/VexA family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18740 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE95 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/568768:Dpoa569_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. RhlB subfamily.|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA. http://togogenome.org/gene/568768:Dpoa569_RS09535 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBA9 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10B family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/568768:Dpoa569_RS08955 ^@ http://purl.uniprot.org/uniprot/A0A5B8I618 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/568768:Dpoa569_RS04740 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3F1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamB family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/568768:Dpoa569_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9N0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/568768:Dpoa569_RS15945 ^@ http://purl.uniprot.org/uniprot/A0A5B8HS89 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/568768:Dpoa569_RS13970 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQI1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS13540 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9F8 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/568768:Dpoa569_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A5B8I082 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04850 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3N1 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB. http://togogenome.org/gene/568768:Dpoa569_RS01745 ^@ http://purl.uniprot.org/uniprot/A0A5B8I189 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/568768:Dpoa569_RS13145 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID61 ^@ Function|||Similarity|||Subunit ^@ Belongs to the AB hydrolase superfamily. MenH family.|||Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS13615 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQP1 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/568768:Dpoa569_RS14970 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18455 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRP9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HemG family.|||Belongs to the flavodoxin family.|||Binds 1 FMN non-covalently per subunit.|||Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS15100 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8L9 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-II family. http://togogenome.org/gene/568768:Dpoa569_RS05390 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2B4 ^@ Similarity ^@ Belongs to the isochorismate synthase family. http://togogenome.org/gene/568768:Dpoa569_RS01930 ^@ http://purl.uniprot.org/uniprot/A0A5B8HG35 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||Involved in both the arginine and lysine biosynthetic pathways. http://togogenome.org/gene/568768:Dpoa569_RS02600 ^@ http://purl.uniprot.org/uniprot/A0A5B8I285 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/568768:Dpoa569_RS02725 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0A0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the YjjX NTPase family.|||Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).|||Homodimer.|||Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/568768:Dpoa569_RS00530 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0I8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS07460 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKN7 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/568768:Dpoa569_RS09835 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID63 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/568768:Dpoa569_RS02320 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1W5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. http://togogenome.org/gene/568768:Dpoa569_RS12200 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS11615 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CitD family.|||Covalent carrier of the coenzyme of citrate lyase.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6. http://togogenome.org/gene/568768:Dpoa569_RS04385 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS09870 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS17770 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBM1 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/568768:Dpoa569_RS01005 ^@ http://purl.uniprot.org/uniprot/A0A5B8HE20 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS15765 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ37 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/568768:Dpoa569_RS10015 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKG5 ^@ Similarity ^@ Belongs to the UPF0229 family. http://togogenome.org/gene/568768:Dpoa569_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A5B8HI14 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/568768:Dpoa569_RS16780 ^@ http://purl.uniprot.org/uniprot/A0A5B8HS06 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MzrA family.|||Cell inner membrane|||Interacts with EnvZ.|||Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. http://togogenome.org/gene/568768:Dpoa569_RS05110 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS07185 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBA8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliN/MopA/SpaO family.|||Cell membrane|||FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10115 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMX6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/568768:Dpoa569_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1T9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/568768:Dpoa569_RS07595 ^@ http://purl.uniprot.org/uniprot/A0A5B8I556 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.|||Cell inner membrane|||Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.|||The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE). http://togogenome.org/gene/568768:Dpoa569_RS18140 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBV3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/568768:Dpoa569_RS09715 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMK3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS05655 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJ30 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DedD family.|||Cell inner membrane|||Non-essential cell division protein that could be required for efficient cell constriction.|||The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring. http://togogenome.org/gene/568768:Dpoa569_RS05310 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5R0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell inner membrane|||Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS08615 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4D8 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/568768:Dpoa569_RS01535 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS13025 ^@ http://purl.uniprot.org/uniprot/A0A5B8I949 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaA family. HdA subfamily.|||Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.|||The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN). http://togogenome.org/gene/568768:Dpoa569_RS13555 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQI9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/568768:Dpoa569_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0X6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS02940 ^@ http://purl.uniprot.org/uniprot/A0A5B8I289 ^@ Domain|||Function|||Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Homodimer.|||Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.|||The transmembrane domain is a dimerization domain. http://togogenome.org/gene/568768:Dpoa569_RS19345 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTF9 ^@ Function|||Similarity ^@ Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.|||Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. http://togogenome.org/gene/568768:Dpoa569_RS00685 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0N3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PanZ/PanM family.|||Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.|||Interacts with PanD in the presence of CoA. http://togogenome.org/gene/568768:Dpoa569_RS08920 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5Z6 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS07500 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9Y9 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/568768:Dpoa569_RS18285 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AaeX family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS03395 ^@ http://purl.uniprot.org/uniprot/A0A5B8HH96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS02965 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2H7 ^@ Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Dimer of large and small chains. http://togogenome.org/gene/568768:Dpoa569_RS04685 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3J5 ^@ Function|||Similarity ^@ Belongs to the IscX family.|||May function as iron donor in the assembly of iron-sulfur clusters. http://togogenome.org/gene/568768:Dpoa569_RS14705 ^@ http://purl.uniprot.org/uniprot/A0A5B8IGT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A5B8HE36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/568768:Dpoa569_RS01420 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5Q8 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 26 family.|||Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. http://togogenome.org/gene/568768:Dpoa569_RS17690 ^@ http://purl.uniprot.org/uniprot/A0A5B8HR81 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/568768:Dpoa569_RS01360 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEC4 ^@ Function|||Similarity ^@ Belongs to the GppA/Ppx family. GppA subfamily.|||Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. http://togogenome.org/gene/568768:Dpoa569_RS19055 ^@ http://purl.uniprot.org/uniprot/A0A5B8IKG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/568768:Dpoa569_RS13965 ^@ http://purl.uniprot.org/uniprot/A0A5B8IB89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16175 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSD8 ^@ Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis. http://togogenome.org/gene/568768:Dpoa569_RS04840 ^@ http://purl.uniprot.org/uniprot/A0A5B8IL38 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A5B8I478 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 5DNU family.|||Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS17150 ^@ http://purl.uniprot.org/uniprot/A0A5B8HT13 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer.|||Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein. http://togogenome.org/gene/568768:Dpoa569_RS18315 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Cell inner membrane|||Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS05885 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4B1 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/568768:Dpoa569_RS16480 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/568768:Dpoa569_RS18560 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm|||In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily. http://togogenome.org/gene/568768:Dpoa569_RS13370 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFU8 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/568768:Dpoa569_RS09795 ^@ http://purl.uniprot.org/uniprot/A0A5B8I522 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/568768:Dpoa569_RS10820 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNH6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.|||Cell membrane|||Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07145 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3F5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.|||In the C-terminal section; belongs to the glycosyl hydrolase 73 family.|||In the N-terminal section; belongs to the FlgJ family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3C7 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/568768:Dpoa569_RS08325 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5K8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. http://togogenome.org/gene/568768:Dpoa569_RS13430 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7D4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/568768:Dpoa569_RS00975 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0N8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/568768:Dpoa569_RS09815 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0259 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15890 ^@ http://purl.uniprot.org/uniprot/A0A5B8HS79 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP J family.|||Cell inner membrane|||Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04030 ^@ http://purl.uniprot.org/uniprot/A0A5B8I345 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/568768:Dpoa569_RS03025 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHI2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/568768:Dpoa569_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGA5 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/568768:Dpoa569_RS15490 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8T9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS03885 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/568768:Dpoa569_RS16675 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/568768:Dpoa569_RS16620 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAU1 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/568768:Dpoa569_RS10580 ^@ http://purl.uniprot.org/uniprot/A0A5B8HL59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/568768:Dpoa569_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A5B8HDU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.|||Belongs to the small heat shock protein (HSP20) family.|||Cytoplasm|||Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations. http://togogenome.org/gene/568768:Dpoa569_RS00600 ^@ http://purl.uniprot.org/uniprot/A0A5B8HDX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Cell membrane|||Membrane|||Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. http://togogenome.org/gene/568768:Dpoa569_RS09045 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7Y2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS16880 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbD subfamily.|||Cell inner membrane|||Membrane|||Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. http://togogenome.org/gene/568768:Dpoa569_RS10530 ^@ http://purl.uniprot.org/uniprot/A0A5B8HL48 ^@ Function|||Similarity ^@ Belongs to the TorD/DmsD family. DmsD subfamily.|||Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein. http://togogenome.org/gene/568768:Dpoa569_RS10410 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:citrate (SCF) symporter family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS01790 ^@ http://purl.uniprot.org/uniprot/A0A5B8I197 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/568768:Dpoa569_RS12475 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPM6 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 Fe cation per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/568768:Dpoa569_RS12870 ^@ http://purl.uniprot.org/uniprot/A0A5B8I905 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS16825 ^@ http://purl.uniprot.org/uniprot/A0A5B8IIG6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/568768:Dpoa569_RS11595 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEE2 ^@ Cofactor|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit. http://togogenome.org/gene/568768:Dpoa569_RS03435 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0T0 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS17550 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18580 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A5B8HT00 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS19060 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEH9 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/568768:Dpoa569_RS18765 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAY3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nucleoid occlusion factor SlmA family.|||Homodimer. Interacts with FtsZ.|||Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.|||nucleoid http://togogenome.org/gene/568768:Dpoa569_RS02925 ^@ http://purl.uniprot.org/uniprot/A0A5B8I751 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||The active site is located at the dimer interface. http://togogenome.org/gene/568768:Dpoa569_RS09215 ^@ http://purl.uniprot.org/uniprot/A0A5B8HM68 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/568768:Dpoa569_RS17705 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS17070 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBK0 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/568768:Dpoa569_RS01695 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEJ6 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/568768:Dpoa569_RS03085 ^@ http://purl.uniprot.org/uniprot/A0A5B8I782 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS09405 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6G6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/568768:Dpoa569_RS13890 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9L8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS01690 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBE9 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/568768:Dpoa569_RS12580 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8T5 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/568768:Dpoa569_RS05525 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDE5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. Thiolase family.|||Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.|||Cytoplasm|||Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI). http://togogenome.org/gene/568768:Dpoa569_RS12180 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07575 ^@ http://purl.uniprot.org/uniprot/A0A5B8I592 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/568768:Dpoa569_RS04320 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3A4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1Z8 ^@ Caution|||Similarity ^@ Belongs to the phosphoglycerate mutase family. GpmB subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS00120 ^@ http://purl.uniprot.org/uniprot/A0A5Q2V719 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/568768:Dpoa569_RS12665 ^@ http://purl.uniprot.org/uniprot/A0A5B8IF72 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/568768:Dpoa569_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A5B8HM01 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/568768:Dpoa569_RS09930 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID83 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/568768:Dpoa569_RS10190 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6U4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS07580 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3Q8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS12170 ^@ http://purl.uniprot.org/uniprot/A0A5B8I876 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DyP-type peroxidase family. EfeB subfamily.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.|||Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.|||Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS14120 ^@ http://purl.uniprot.org/uniprot/A0A5B8I969 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP K family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04455 ^@ http://purl.uniprot.org/uniprot/A0A5B8I812 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS12100 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0299 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS09200 ^@ http://purl.uniprot.org/uniprot/A0A5B8HM67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/568768:Dpoa569_RS17885 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC09 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/568768:Dpoa569_RS16020 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAI0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit.|||Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. http://togogenome.org/gene/568768:Dpoa569_RS10565 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5L6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS09230 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4N9 ^@ Similarity ^@ Belongs to the UPF0260 family. http://togogenome.org/gene/568768:Dpoa569_RS13995 ^@ http://purl.uniprot.org/uniprot/A0A5B8I947 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/568768:Dpoa569_RS15315 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8Q0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/568768:Dpoa569_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0W0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS13410 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAR9 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/568768:Dpoa569_RS00365 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5H5 ^@ Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family. DsdA subfamily.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS17370 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBQ9 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/568768:Dpoa569_RS16800 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10650 ^@ http://purl.uniprot.org/uniprot/A0A5B8I962 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS03535 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2R6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS15285 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRV7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS00135 ^@ http://purl.uniprot.org/uniprot/A0A5B8HYA2 ^@ Similarity|||Subunit ^@ Belongs to the ViaA family.|||Possible formation of a ternary complex RavA-ViaA-CadA. http://togogenome.org/gene/568768:Dpoa569_RS18885 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16555 ^@ http://purl.uniprot.org/uniprot/A0A5B8II80 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/568768:Dpoa569_RS08985 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAX6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A5B8I535 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. SrmB subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.|||Interacts with the 50S ribosomal subunit. http://togogenome.org/gene/568768:Dpoa569_RS13645 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7I2 ^@ Function|||Similarity ^@ Belongs to the nucleoside phosphorylase PpnP family.|||Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. http://togogenome.org/gene/568768:Dpoa569_RS00895 ^@ http://purl.uniprot.org/uniprot/A0A5B8HDZ4 ^@ Cofactor|||Similarity ^@ Belongs to the alkaline phosphatase family.|||Binds 1 Mg(2+) ion.|||Binds 2 Zn(2+) ions. http://togogenome.org/gene/568768:Dpoa569_RS02800 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1P9 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/568768:Dpoa569_RS18630 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS03670 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2P7 ^@ Cofactor|||Function ^@ Binds 1 [2Fe-2S] cluster per subunit.|||Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. http://togogenome.org/gene/568768:Dpoa569_RS00605 ^@ http://purl.uniprot.org/uniprot/A0A5B8HF28 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/568768:Dpoa569_RS01710 ^@ http://purl.uniprot.org/uniprot/A0A5B8I171 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS13720 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE67 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS17965 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS02750 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6I8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS00345 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEX2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/568768:Dpoa569_RS09825 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8E8 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/568768:Dpoa569_RS04710 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5D3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/568768:Dpoa569_RS12385 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8C2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS04545 ^@ http://purl.uniprot.org/uniprot/A0A5B8I561 ^@ Function|||Induction|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/568768:Dpoa569_RS02540 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGH9 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/568768:Dpoa569_RS09185 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6B2 ^@ Similarity ^@ Belongs to the KAE1 / TsaD family. TsaB subfamily. http://togogenome.org/gene/568768:Dpoa569_RS02660 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGL2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/568768:Dpoa569_RS10955 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/568768:Dpoa569_RS07220 ^@ http://purl.uniprot.org/uniprot/A0A5B8HK75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS13545 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8W6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/568768:Dpoa569_RS07695 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3T2 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/568768:Dpoa569_RS19075 ^@ http://purl.uniprot.org/uniprot/A0A5B8ILZ0 ^@ Similarity ^@ Belongs to the mannitol dehydrogenase family. http://togogenome.org/gene/568768:Dpoa569_RS07770 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ribosome modulation factor family.|||Cytoplasm|||During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes). http://togogenome.org/gene/568768:Dpoa569_RS17235 ^@ http://purl.uniprot.org/uniprot/A0A5B8HS83 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.|||Belongs to the ZapA family. Type 1 subfamily.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/568768:Dpoa569_RS02955 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGY2 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/568768:Dpoa569_RS10935 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9B6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/568768:Dpoa569_RS03715 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2W3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/568768:Dpoa569_RS15660 ^@ http://purl.uniprot.org/uniprot/A0A5B8HS40 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS15460 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRZ8 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/568768:Dpoa569_RS15715 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ29 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Cytoplasm|||Homodimer.|||Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. http://togogenome.org/gene/568768:Dpoa569_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTN3 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/568768:Dpoa569_RS03055 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2A5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/568768:Dpoa569_RS02140 ^@ http://purl.uniprot.org/uniprot/A0A5B8I649 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/568768:Dpoa569_RS15185 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA18 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/568768:Dpoa569_RS05135 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS03075 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2K8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS19230 ^@ http://purl.uniprot.org/uniprot/A0A5B8IKL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.|||Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS04705 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7U4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/568768:Dpoa569_RS16590 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQL2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16515 ^@ http://purl.uniprot.org/uniprot/A0A5B8IB78 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase U32 family. UbiU subfamily.|||Forms an heterodimer with UbiV.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway. http://togogenome.org/gene/568768:Dpoa569_RS07330 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thioester dehydratase family. FabA subfamily.|||Cytoplasm|||Homodimer.|||Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. http://togogenome.org/gene/568768:Dpoa569_RS10090 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6R9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.|||Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS04485 ^@ http://purl.uniprot.org/uniprot/A0A5B8HI52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15635 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAA6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CysZ family.|||Cell inner membrane|||High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. http://togogenome.org/gene/568768:Dpoa569_RS07995 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJ28 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/568768:Dpoa569_RS11250 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS01975 ^@ http://purl.uniprot.org/uniprot/A0A5B8HER7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.|||Cell inner membrane|||Interacts with the regulatory subunit KefG.|||Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. http://togogenome.org/gene/568768:Dpoa569_RS01335 ^@ http://purl.uniprot.org/uniprot/A0A5B8I620 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS12970 ^@ http://purl.uniprot.org/uniprot/A0A5B8I737 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0370 family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS01865 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSB8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS03385 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2H5 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/568768:Dpoa569_RS00955 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5U4 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/568768:Dpoa569_RS14030 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQJ5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetyltransferase family. ArgA subfamily.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/568768:Dpoa569_RS07675 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Gram-negative porin family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18415 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS17810 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS07355 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBD8 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS13945 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Syd family.|||Cell inner membrane|||Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. http://togogenome.org/gene/568768:Dpoa569_RS18290 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJV8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS09275 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICT6 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.|||Belongs to the RecD family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/568768:Dpoa569_RS16395 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9B9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA-modifying YgfZ family.|||Cytoplasm|||Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication. http://togogenome.org/gene/568768:Dpoa569_RS16120 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16500 ^@ http://purl.uniprot.org/uniprot/A0A5B8II68 ^@ Similarity ^@ Belongs to the UPF0213 family. http://togogenome.org/gene/568768:Dpoa569_RS04860 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGP0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane|||Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. http://togogenome.org/gene/568768:Dpoa569_RS07565 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKR1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/568768:Dpoa569_RS15270 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/568768:Dpoa569_RS18355 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAR1 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/568768:Dpoa569_RS11775 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7V3 ^@ Function|||Similarity ^@ Belongs to the PhnJ family.|||Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. http://togogenome.org/gene/568768:Dpoa569_RS02875 ^@ http://purl.uniprot.org/uniprot/A0A5B8I736 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/568768:Dpoa569_RS07905 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKZ6 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily.|||Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. http://togogenome.org/gene/568768:Dpoa569_RS15625 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRF1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS03615 ^@ http://purl.uniprot.org/uniprot/A0A5B8I740 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/568768:Dpoa569_RS09695 ^@ http://purl.uniprot.org/uniprot/A0A5B8I502 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/568768:Dpoa569_RS11585 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9P6 ^@ Cofactor|||Function ^@ Binds 4 [4Fe-4S] clusters per subunit.|||The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. http://togogenome.org/gene/568768:Dpoa569_RS03920 ^@ http://purl.uniprot.org/uniprot/A0A5B8I302 ^@ Function|||Similarity ^@ Belongs to the GlnE family.|||Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell. http://togogenome.org/gene/568768:Dpoa569_RS12890 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDJ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/568768:Dpoa569_RS03755 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2W6 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/568768:Dpoa569_RS06790 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4R3 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/568768:Dpoa569_RS07835 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA70 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.|||Belongs to the Lpp family.|||Cell outer membrane|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||cell wall http://togogenome.org/gene/568768:Dpoa569_RS18405 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07235 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKI4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FliT family.|||Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.|||Homodimer. Interacts with FliD and FlhC.|||cytosol http://togogenome.org/gene/568768:Dpoa569_RS00790 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5Q9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/568768:Dpoa569_RS18015 ^@ http://purl.uniprot.org/uniprot/A0A5B8HVF0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase class-III family.|||Binds 2 Fe(2+) ions per subunit.|||Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. http://togogenome.org/gene/568768:Dpoa569_RS10795 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7A8 ^@ Function|||Similarity ^@ Belongs to the esterase D family.|||Serine hydrolase involved in the detoxification of formaldehyde. http://togogenome.org/gene/568768:Dpoa569_RS13955 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQX0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Xni family.|||Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.|||Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.|||Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. http://togogenome.org/gene/568768:Dpoa569_RS00115 ^@ http://purl.uniprot.org/uniprot/A0A5Q2V5J8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS09985 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMS6 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/568768:Dpoa569_RS11335 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7K8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0299 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04855 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3H3 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC. http://togogenome.org/gene/568768:Dpoa569_RS16775 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS08245 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC29 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS00555 ^@ http://purl.uniprot.org/uniprot/A0A5B8HF21 ^@ Similarity ^@ Belongs to the HipA Ser/Thr kinase family. http://togogenome.org/gene/568768:Dpoa569_RS02350 ^@ http://purl.uniprot.org/uniprot/A0A5B8I014 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS12905 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/568768:Dpoa569_RS00305 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5F7 ^@ Caution|||Function|||Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS09150 ^@ http://purl.uniprot.org/uniprot/A0A5B8I806 ^@ Similarity ^@ Belongs to the UPF0053 family. http://togogenome.org/gene/568768:Dpoa569_RS15465 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFB0 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/568768:Dpoa569_RS14075 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQZ4 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/568768:Dpoa569_RS04440 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7N2 ^@ Function ^@ Acts as a radical domain for damaged PFL and possibly other radical proteins. http://togogenome.org/gene/568768:Dpoa569_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7D3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KdgT transporter family.|||Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJ84 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIC5 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/568768:Dpoa569_RS03205 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2H9 ^@ Similarity ^@ Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family. http://togogenome.org/gene/568768:Dpoa569_RS04260 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIK4 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/568768:Dpoa569_RS09390 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICV5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Heterodimer of an alpha and a beta chain.|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/568768:Dpoa569_RS02680 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1Y5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LysR transcriptional regulatory family.|||Controls the transcription of genes involved in arginine and lysine metabolism.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS17825 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBN2 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/568768:Dpoa569_RS17035 ^@ http://purl.uniprot.org/uniprot/A0A5B8IIN5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/568768:Dpoa569_RS10595 ^@ http://purl.uniprot.org/uniprot/A0A5B8I952 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS05340 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3T5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP L family.|||Cell inner membrane|||Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04180 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHX9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Binds 2 Zn(2+) ions per subunit.|||Monomer.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/568768:Dpoa569_RS17845 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRB5 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS14235 ^@ http://purl.uniprot.org/uniprot/A0A5B8HR34 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/568768:Dpoa569_RS19255 ^@ http://purl.uniprot.org/uniprot/A0A5B8IB83 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/568768:Dpoa569_RS06040 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHL2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/568768:Dpoa569_RS12350 ^@ http://purl.uniprot.org/uniprot/A0A5B8I850 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10165 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMZ3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.|||Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJL9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/568768:Dpoa569_RS16135 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAL1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. WecA subfamily.|||Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07925 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5I7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SlyA family.|||Homodimer.|||Transcription regulator that can specifically activate or repress expression of target genes. http://togogenome.org/gene/568768:Dpoa569_RS10295 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MukE family.|||Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.|||Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.|||nucleoid http://togogenome.org/gene/568768:Dpoa569_RS12930 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8H3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS19040 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC63 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS10780 ^@ http://purl.uniprot.org/uniprot/A0A5B8HU53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS11280 ^@ http://purl.uniprot.org/uniprot/A0A5B8I630 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS00160 ^@ http://purl.uniprot.org/uniprot/A0A5B8HET0 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04420 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGF2 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/568768:Dpoa569_RS09015 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4J4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/568768:Dpoa569_RS17900 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTH6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS09890 ^@ http://purl.uniprot.org/uniprot/A0A5B8I553 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/568768:Dpoa569_RS13960 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEB4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.|||Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.|||Cytoplasm|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS13015 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8U0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48 family. BepA subfamily.|||Binds 1 zinc ion per subunit.|||Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS16550 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRW0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5H4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraA family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.|||Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB. http://togogenome.org/gene/568768:Dpoa569_RS04010 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIE1 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS17995 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBF3 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/568768:Dpoa569_RS12260 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPN7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0M5 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/568768:Dpoa569_RS05760 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJ63 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS11200 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16195 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A5B8IB28 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/568768:Dpoa569_RS13975 ^@ http://purl.uniprot.org/uniprot/A0A5B8IGA7 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/568768:Dpoa569_RS00505 ^@ http://purl.uniprot.org/uniprot/A0A5B8I577 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS11970 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPC2 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/568768:Dpoa569_RS02015 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1F9 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS13620 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/568768:Dpoa569_RS01760 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5X4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.|||Cytoplasm|||Monomer.|||The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. http://togogenome.org/gene/568768:Dpoa569_RS00670 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0G7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/568768:Dpoa569_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5L4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:citrate (SCF) symporter family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS01370 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5P9 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/568768:Dpoa569_RS16490 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICV4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer.|||The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. http://togogenome.org/gene/568768:Dpoa569_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A5B8HYM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS17975 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJL4 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/568768:Dpoa569_RS18530 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/568768:Dpoa569_RS11950 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6F5 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/568768:Dpoa569_RS03950 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7A9 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS08965 ^@ http://purl.uniprot.org/uniprot/A0A5B8I637 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07285 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9Q4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sigma-70 factor family. FliA subfamily.|||Cytoplasm|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. http://togogenome.org/gene/568768:Dpoa569_RS18475 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE40 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/568768:Dpoa569_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3W2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the thioesterase PaaI family.|||Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).|||Homotetramer. Dimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS10500 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS01060 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0Q3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/568768:Dpoa569_RS15530 ^@ http://purl.uniprot.org/uniprot/A0A5B8IHH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS04865 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1I7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/568768:Dpoa569_RS09660 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS02840 ^@ http://purl.uniprot.org/uniprot/A0A5B8I223 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS05510 ^@ http://purl.uniprot.org/uniprot/A0A5B8I429 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/568768:Dpoa569_RS18525 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/568768:Dpoa569_RS10130 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMX8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/568768:Dpoa569_RS17745 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS10065 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMV9 ^@ Similarity|||Subunit ^@ Belongs to the KHG/KDPG aldolase family.|||Homotrimer. http://togogenome.org/gene/568768:Dpoa569_RS04205 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIJ3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/568768:Dpoa569_RS04310 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIL1 ^@ Function|||Similarity ^@ Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/568768:Dpoa569_RS10720 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDU1 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/568768:Dpoa569_RS14130 ^@ http://purl.uniprot.org/uniprot/A0A5B8HR10 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS00145 ^@ http://purl.uniprot.org/uniprot/A0A5B8I047 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell membrane|||Membrane|||Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter. http://togogenome.org/gene/568768:Dpoa569_RS09915 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBJ0 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the RssB family.|||Binds to RpoS.|||Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.|||Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. http://togogenome.org/gene/568768:Dpoa569_RS02585 ^@ http://purl.uniprot.org/uniprot/A0A5B8HF45 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS15605 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ07 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS13575 ^@ http://purl.uniprot.org/uniprot/A0A5B8IG14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/568768:Dpoa569_RS10435 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBW4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2A7 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/568768:Dpoa569_RS13445 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS13155 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAM4 ^@ Function|||Similarity ^@ Belongs to the isochorismate synthase family.|||Catalyzes the conversion of chorismate to isochorismate. http://togogenome.org/gene/568768:Dpoa569_RS15550 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9Z4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS09530 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMF9 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/568768:Dpoa569_RS13360 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAR3 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/568768:Dpoa569_RS18230 ^@ http://purl.uniprot.org/uniprot/A0A5B8HST1 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/568768:Dpoa569_RS13760 ^@ http://purl.uniprot.org/uniprot/A0A5B8I993 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/568768:Dpoa569_RS03070 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6R2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.|||nucleoid http://togogenome.org/gene/568768:Dpoa569_RS07445 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKH1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/568768:Dpoa569_RS00635 ^@ http://purl.uniprot.org/uniprot/A0A5B8HYR1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/568768:Dpoa569_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A5B8I662 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/568768:Dpoa569_RS04335 ^@ http://purl.uniprot.org/uniprot/A0A5B8I353 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.|||Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS02795 ^@ http://purl.uniprot.org/uniprot/A0A5B8I245 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS03890 ^@ http://purl.uniprot.org/uniprot/A0A5B8I793 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably interacts with PlsX. http://togogenome.org/gene/568768:Dpoa569_RS07485 ^@ http://purl.uniprot.org/uniprot/A0A5B8I531 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/568768:Dpoa569_RS03910 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIA5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS07465 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBG1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS17680 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/568768:Dpoa569_RS19390 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEQ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/568768:Dpoa569_RS14145 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQL7 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/568768:Dpoa569_RS03525 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS00105 ^@ http://purl.uniprot.org/uniprot/A0A5Q2V4R8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16475 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQJ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein bS18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS05700 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHB6 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/568768:Dpoa569_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5N6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M14 family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap. http://togogenome.org/gene/568768:Dpoa569_RS10515 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID16 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS05765 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8P3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/568768:Dpoa569_RS13480 ^@ http://purl.uniprot.org/uniprot/A0A5B8I948 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS01660 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEF1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transcriptional regulatory CopG/NikR family.|||Binds 1 nickel ion per subunit.|||Homotetramer.|||Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel. http://togogenome.org/gene/568768:Dpoa569_RS19370 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICD8 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/568768:Dpoa569_RS05810 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJ77 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/568768:Dpoa569_RS09575 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6K6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/568768:Dpoa569_RS10440 ^@ http://purl.uniprot.org/uniprot/A0A5B8I920 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS00330 ^@ http://purl.uniprot.org/uniprot/A0A5B8HDQ7 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigB subfamily.|||Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. http://togogenome.org/gene/568768:Dpoa569_RS11705 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEH0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS16850 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9T1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/568768:Dpoa569_RS05170 ^@ http://purl.uniprot.org/uniprot/A0A5B8I266 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 3 family.|||Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.|||Secreted http://togogenome.org/gene/568768:Dpoa569_RS07475 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3M9 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/568768:Dpoa569_RS03020 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2J6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/568768:Dpoa569_RS19125 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16495 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRV0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS17240 ^@ http://purl.uniprot.org/uniprot/A0A5B8IIY0 ^@ Similarity ^@ Belongs to the UPF0149 family. http://togogenome.org/gene/568768:Dpoa569_RS19380 ^@ http://purl.uniprot.org/uniprot/A0A5B8HUJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/568768:Dpoa569_RS08100 ^@ http://purl.uniprot.org/uniprot/A0A5B8HL12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0283 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS13875 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9B4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS03155 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2C9 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.|||Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM. http://togogenome.org/gene/568768:Dpoa569_RS10635 ^@ http://purl.uniprot.org/uniprot/A0A5B8HL73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS16640 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQM4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/568768:Dpoa569_RS05450 ^@ http://purl.uniprot.org/uniprot/A0A5B8I418 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/568768:Dpoa569_RS08040 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5E6 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/568768:Dpoa569_RS14965 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS01615 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1B6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anaerobic G-3-P dehydrogenase subunit B family.|||Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.|||Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor. http://togogenome.org/gene/568768:Dpoa569_RS01140 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0S1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/568768:Dpoa569_RS05650 ^@ http://purl.uniprot.org/uniprot/A0A5B8HH66 ^@ Function|||Similarity ^@ Belongs to the folylpolyglutamate synthase family.|||Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. http://togogenome.org/gene/568768:Dpoa569_RS05015 ^@ http://purl.uniprot.org/uniprot/A0A5B8I232 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS00680 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5P1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/568768:Dpoa569_RS02665 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6Y5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS01870 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5Z2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS18345 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJX4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MsrQ family.|||Binds 1 FMN per subunit.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Cell membrane|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain. http://togogenome.org/gene/568768:Dpoa569_RS07590 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS02370 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGE6 ^@ Similarity ^@ Belongs to the radical SAM superfamily. KamA family. http://togogenome.org/gene/568768:Dpoa569_RS16625 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9N1 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/568768:Dpoa569_RS04480 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGG3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/568768:Dpoa569_RS18890 ^@ http://purl.uniprot.org/uniprot/A0A5B8HU80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS01375 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0Y0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure. http://togogenome.org/gene/568768:Dpoa569_RS00150 ^@ http://purl.uniprot.org/uniprot/A0A5B8HDL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbsD / FucU family. RbsD subfamily.|||Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.|||Cytoplasm|||Homodecamer. http://togogenome.org/gene/568768:Dpoa569_RS11960 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7W9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS05665 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5Y6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS01675 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZH9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS11865 ^@ http://purl.uniprot.org/uniprot/A0A5B8HM92 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.|||Catalyzes the proton-dependent transport of glutamate and aspartate.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS02095 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1L6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/568768:Dpoa569_RS09125 ^@ http://purl.uniprot.org/uniprot/A0A5B8I679 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0266 family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS08205 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5P8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/568768:Dpoa569_RS11730 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS01030 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZ15 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.|||Cell outer membrane|||Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS05055 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8D5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxH family.|||Binds 2 Mn(2+) ions per subunit in a binuclear metal center.|||Cell inner membrane|||Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/568768:Dpoa569_RS09900 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6L8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS11020 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5V4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/568768:Dpoa569_RS19095 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS09175 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4M6 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/568768:Dpoa569_RS02110 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1Q6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/568768:Dpoa569_RS00315 ^@ http://purl.uniprot.org/uniprot/A0A5B8HYF6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/568768:Dpoa569_RS05060 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3S2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/568768:Dpoa569_RS03220 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2F3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS07850 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS18985 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICW3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/568768:Dpoa569_RS08025 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5K3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNR ribonuclease family. RNase II subfamily.|||Cytoplasm|||Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction. http://togogenome.org/gene/568768:Dpoa569_RS10330 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBU3 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/568768:Dpoa569_RS01880 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEJ3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/568768:Dpoa569_RS13035 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN55 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/568768:Dpoa569_RS00225 ^@ http://purl.uniprot.org/uniprot/A0A5B8I059 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbA subfamily.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS09080 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJU8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/568768:Dpoa569_RS11340 ^@ http://purl.uniprot.org/uniprot/A0A5B8HV41 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS08715 ^@ http://purl.uniprot.org/uniprot/A0A5B8HLU7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/568768:Dpoa569_RS06755 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6G3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/568768:Dpoa569_RS00815 ^@ http://purl.uniprot.org/uniprot/A0A5B8HE24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS09360 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDP6 ^@ Similarity ^@ Belongs to the UPF0162 family. http://togogenome.org/gene/568768:Dpoa569_RS10035 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/568768:Dpoa569_RS07790 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS14085 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEE4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MutH family.|||Cytoplasm|||Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. http://togogenome.org/gene/568768:Dpoa569_RS17275 ^@ http://purl.uniprot.org/uniprot/A0A5B8IIU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/568768:Dpoa569_RS16125 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRQ0 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/568768:Dpoa569_RS01950 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6H5 ^@ Similarity ^@ Belongs to the UPF0270 family. http://togogenome.org/gene/568768:Dpoa569_RS10420 ^@ http://purl.uniprot.org/uniprot/A0A5B8I724 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS18110 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRH0 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/568768:Dpoa569_RS18920 ^@ http://purl.uniprot.org/uniprot/A0A5B8IB14 ^@ Similarity ^@ Belongs to the autoinducer synthase family. http://togogenome.org/gene/568768:Dpoa569_RS18540 ^@ http://purl.uniprot.org/uniprot/A0A5B8IK20 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC1 family. UbiB subfamily.|||Cell membrane|||Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0W6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS01750 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEL0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NfuA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.|||Homodimer.|||Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. http://togogenome.org/gene/568768:Dpoa569_RS01275 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0V0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS14655 ^@ http://purl.uniprot.org/uniprot/A0A5B8IGR4 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/568768:Dpoa569_RS15045 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9Z5 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/568768:Dpoa569_RS16650 ^@ http://purl.uniprot.org/uniprot/A0A5B8IIB4 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/568768:Dpoa569_RS12550 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CpoB family.|||Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS16200 ^@ http://purl.uniprot.org/uniprot/A0A5B8II19 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.|||Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(acyl)-lipid IV(A).|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS00255 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5E7 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. http://togogenome.org/gene/568768:Dpoa569_RS01035 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0Q1 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/568768:Dpoa569_RS06055 ^@ http://purl.uniprot.org/uniprot/A0A5B8I652 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/568768:Dpoa569_RS16430 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRT7 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/568768:Dpoa569_RS04905 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3I4 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/568768:Dpoa569_RS18905 ^@ http://purl.uniprot.org/uniprot/A0A5B8HT61 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS08930 ^@ http://purl.uniprot.org/uniprot/A0A5B8HLX4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.|||Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site. http://togogenome.org/gene/568768:Dpoa569_RS18520 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTY4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.|||Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS12575 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbB/TolQ family.|||Cell inner membrane|||Membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/568768:Dpoa569_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A5B8I820 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04775 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3K3 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS10575 ^@ http://purl.uniprot.org/uniprot/A0A5B8I757 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/568768:Dpoa569_RS04935 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8C0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS05730 ^@ http://purl.uniprot.org/uniprot/A0A5B8I480 ^@ Similarity ^@ Belongs to the UPF0304 family. http://togogenome.org/gene/568768:Dpoa569_RS10460 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5J0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/568768:Dpoa569_RS19285 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. http://togogenome.org/gene/568768:Dpoa569_RS10465 ^@ http://purl.uniprot.org/uniprot/A0A5B8I796 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/568768:Dpoa569_RS07205 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4X4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Flagellar protein that affects chemotactic events.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS01115 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0R7 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/568768:Dpoa569_RS07885 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIZ2 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/568768:Dpoa569_RS18245 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAP2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RapZ-like family. RapZ subfamily.|||Homotrimer.|||Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS. http://togogenome.org/gene/568768:Dpoa569_RS02520 ^@ http://purl.uniprot.org/uniprot/A0A5B8I044 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueG family.|||Binds 2 [4Fe-4S] clusters per monomer.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS07110 ^@ http://purl.uniprot.org/uniprot/A0A5B8HID9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/568768:Dpoa569_RS17985 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAI8 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/568768:Dpoa569_RS12450 ^@ http://purl.uniprot.org/uniprot/A0A5B8I871 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.|||Belongs to the AcrZ family.|||Cell membrane|||Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB. http://togogenome.org/gene/568768:Dpoa569_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9J6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the cytochrome b562 family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.|||Electron-transport protein of unknown function. http://togogenome.org/gene/568768:Dpoa569_RS06065 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAG2 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/568768:Dpoa569_RS09355 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6A5 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/568768:Dpoa569_RS06170 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4G5 ^@ Similarity ^@ Belongs to the MobA/MobL family. http://togogenome.org/gene/568768:Dpoa569_RS04555 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIR4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase Slt family.|||Cell outer membrane|||In the C-terminal section; belongs to the transglycosylase Slt family.|||In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.|||The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain. http://togogenome.org/gene/568768:Dpoa569_RS07335 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKA1 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/568768:Dpoa569_RS15380 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9W5 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/568768:Dpoa569_RS12005 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6G8 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS03320 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2H6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/568768:Dpoa569_RS10450 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDN6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/568768:Dpoa569_RS07820 ^@ http://purl.uniprot.org/uniprot/A0A5B8I597 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo.|||Cytoplasm|||Homodimer. Interacts with SufE and the SufBCD complex composed of SufB, SufC and SufD. The interaction with SufE is required to mediate the direct transfer of the sulfur atom from the S-sulfanylcysteine. http://togogenome.org/gene/568768:Dpoa569_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2K3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15740 ^@ http://purl.uniprot.org/uniprot/A0A5B8IHP5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/568768:Dpoa569_RS13425 ^@ http://purl.uniprot.org/uniprot/A0A5B8I936 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/568768:Dpoa569_RS11055 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNL9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS09010 ^@ http://purl.uniprot.org/uniprot/A0A5B8I632 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/568768:Dpoa569_RS07780 ^@ http://purl.uniprot.org/uniprot/A0A5B8I750 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/568768:Dpoa569_RS15400 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS15590 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8X1 ^@ Similarity ^@ Belongs to the alkylbase DNA glycosidase AlkA family. http://togogenome.org/gene/568768:Dpoa569_RS09315 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMA1 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/568768:Dpoa569_RS01390 ^@ http://purl.uniprot.org/uniprot/A0A5B8I157 ^@ Function|||Similarity|||Subunit ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.|||Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS10665 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS04670 ^@ http://purl.uniprot.org/uniprot/A0A5B8I863 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HscB family.|||Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.|||Interacts with HscA and stimulates its ATPase activity. Interacts with IscU. http://togogenome.org/gene/568768:Dpoa569_RS18750 ^@ http://purl.uniprot.org/uniprot/A0A5B8IK93 ^@ Similarity ^@ Belongs to the UPF0758 family. YicR subfamily. http://togogenome.org/gene/568768:Dpoa569_RS11965 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMC4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS00055 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTI6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family. http://togogenome.org/gene/568768:Dpoa569_RS18800 ^@ http://purl.uniprot.org/uniprot/A0A5B8HT41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS00985 ^@ http://purl.uniprot.org/uniprot/A0A5B8HE54 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/568768:Dpoa569_RS15050 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8K7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS13515 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAY0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS11875 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICX4 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/568768:Dpoa569_RS17945 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the rhamnose mutarotase family.|||Cytoplasm|||Homodimer.|||Involved in the anomeric conversion of L-rhamnose. http://togogenome.org/gene/568768:Dpoa569_RS11635 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9Q6 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/568768:Dpoa569_RS03245 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2Q2 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/568768:Dpoa569_RS02765 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGN5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS10340 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS03285 ^@ http://purl.uniprot.org/uniprot/A0A5B8HH73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS05350 ^@ http://purl.uniprot.org/uniprot/A0A5B8IL82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/568768:Dpoa569_RS03290 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6W2 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/568768:Dpoa569_RS18075 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDT5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SIS family. DiaA subfamily.|||Homotetramer; dimer of dimers.|||Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. http://togogenome.org/gene/568768:Dpoa569_RS00390 ^@ http://purl.uniprot.org/uniprot/A0A5B8HDS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Gram-negative porin family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16390 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAQ1 ^@ Similarity ^@ Belongs to the SdhE FAD assembly factor family. http://togogenome.org/gene/568768:Dpoa569_RS11410 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7K3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MtfA family.|||Cytoplasm|||Interacts with Mlc.|||Involved in the regulation of ptsG expression by binding and inactivating Mlc. http://togogenome.org/gene/568768:Dpoa569_RS12915 ^@ http://purl.uniprot.org/uniprot/A0A5B8I718 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/568768:Dpoa569_RS03995 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHS5 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.|||Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS05305 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8E2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.|||Belongs to the GSP E family.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS11535 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9N5 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/568768:Dpoa569_RS04795 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGM9 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/568768:Dpoa569_RS13275 ^@ http://purl.uniprot.org/uniprot/A0A5B8I799 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/568768:Dpoa569_RS15755 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAQ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamE family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/568768:Dpoa569_RS00050 ^@ http://purl.uniprot.org/uniprot/A0A5B8IER9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS19015 ^@ http://purl.uniprot.org/uniprot/A0A5B8HT77 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/568768:Dpoa569_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A5B8I452 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS05545 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8J3 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.|||Methylates ribosomal protein uL3 on a specific glutamine residue. http://togogenome.org/gene/568768:Dpoa569_RS12855 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS17355 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJ12 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/568768:Dpoa569_RS06075 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2R3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS09625 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICZ9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. http://togogenome.org/gene/568768:Dpoa569_RS08065 ^@ http://purl.uniprot.org/uniprot/A0A5B8HL40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS07240 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/568768:Dpoa569_RS05585 ^@ http://purl.uniprot.org/uniprot/A0A5B8HH51 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/568768:Dpoa569_RS04770 ^@ http://purl.uniprot.org/uniprot/A0A5B8I886 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/568768:Dpoa569_RS09940 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6N7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10730 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5P6 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/568768:Dpoa569_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A5B8I550 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS07130 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKF9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/568768:Dpoa569_RS02910 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6N0 ^@ Function|||Similarity ^@ Belongs to the Ap4A hydrolase family.|||Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP. http://togogenome.org/gene/568768:Dpoa569_RS07095 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3E5 ^@ Function|||Similarity ^@ Belongs to the FlgM family.|||Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. http://togogenome.org/gene/568768:Dpoa569_RS12995 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamC family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/568768:Dpoa569_RS04055 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3B2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/568768:Dpoa569_RS18170 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJM2 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/568768:Dpoa569_RS12635 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8A7 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/568768:Dpoa569_RS08495 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7L8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PqiA family.|||Component of a transport pathway that contributes to membrane integrity.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS02335 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEU9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AceK family.|||Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS09020 ^@ http://purl.uniprot.org/uniprot/A0A5B8I650 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/568768:Dpoa569_RS18000 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRE8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.|||Cell membrane|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/568768:Dpoa569_RS00950 ^@ http://purl.uniprot.org/uniprot/A0A5B8HE09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS07540 ^@ http://purl.uniprot.org/uniprot/A0A5B8I544 ^@ Similarity ^@ Belongs to the UPF0227 family. http://togogenome.org/gene/568768:Dpoa569_RS13120 ^@ http://purl.uniprot.org/uniprot/A0A5B8I773 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/568768:Dpoa569_RS17990 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsP family.|||Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS07670 ^@ http://purl.uniprot.org/uniprot/A0A5B8I723 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS18480 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSX5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. Thiolase family.|||Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.|||Cytoplasm|||Heterotetramer of two alpha chains (FadB) and two beta chains (FadA). http://togogenome.org/gene/568768:Dpoa569_RS03655 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0Z1 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/568768:Dpoa569_RS14135 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEF8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase Slt family.|||Cell outer membrane|||Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. http://togogenome.org/gene/568768:Dpoa569_RS10950 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7E3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS01125 ^@ http://purl.uniprot.org/uniprot/A0A5B8HE75 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/568768:Dpoa569_RS00415 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein B family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04895 ^@ http://purl.uniprot.org/uniprot/A0A5B8I206 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS13925 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9C5 ^@ Similarity ^@ Belongs to the UPF0325 family. http://togogenome.org/gene/568768:Dpoa569_RS03600 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2N3 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/568768:Dpoa569_RS04255 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18360 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICG8 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/568768:Dpoa569_RS07435 ^@ http://purl.uniprot.org/uniprot/A0A5B8I520 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YceF subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/568768:Dpoa569_RS01990 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1E2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS04580 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3G9 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/568768:Dpoa569_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A5B8I846 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS04035 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2Y5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.|||Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family.|||Binds 1 FAD per subunit.|||Binds 1 FMN per subunit.|||Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||In the N-terminal section; belongs to the flavodoxin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS13170 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8Y0 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the RcsB family.|||Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.|||Interacts with RcsD.|||Phosphorylated and activated by RcsD. http://togogenome.org/gene/568768:Dpoa569_RS07340 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9R5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MatP family.|||Cytoplasm|||Homodimer.|||Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. http://togogenome.org/gene/568768:Dpoa569_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A5B8I139 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phospholipase A1 family.|||Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.|||Cell outer membrane|||Homodimer; dimerization is reversible, and the dimeric form is the active one.|||Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS03465 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2V3 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/568768:Dpoa569_RS11505 ^@ http://purl.uniprot.org/uniprot/A0A5B8I675 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS14860 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9L0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS11045 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICB0 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/568768:Dpoa569_RS09070 ^@ http://purl.uniprot.org/uniprot/A0A5B8I666 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS13175 ^@ http://purl.uniprot.org/uniprot/A0A5B8I781 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.|||Belongs to the RcsC family.|||Cell inner membrane|||Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.|||Interacts with RcsD. http://togogenome.org/gene/568768:Dpoa569_RS10300 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6W8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MukF family.|||Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.|||Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.|||nucleoid http://togogenome.org/gene/568768:Dpoa569_RS09680 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/568768:Dpoa569_RS07985 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5D6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapB family.|||Cell inner membrane|||Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane. http://togogenome.org/gene/568768:Dpoa569_RS10100 ^@ http://purl.uniprot.org/uniprot/A0A5B8I719 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 9 family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS15060 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9R0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS16685 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9P4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/568768:Dpoa569_RS15205 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9T2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/568768:Dpoa569_RS18340 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSV2 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the MsrP family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.|||Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. http://togogenome.org/gene/568768:Dpoa569_RS12360 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BexD/CtrA/VexA family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS13920 ^@ http://purl.uniprot.org/uniprot/A0A5B8IG94 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/568768:Dpoa569_RS00075 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/568768:Dpoa569_RS11060 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS15745 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAC3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS00100 ^@ http://purl.uniprot.org/uniprot/A0A5B8IET0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS00865 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0L3 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/568768:Dpoa569_RS15645 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAN4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS16690 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBB3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/568768:Dpoa569_RS12395 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8L6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/568768:Dpoa569_RS03190 ^@ http://purl.uniprot.org/uniprot/A0A5B8HUP7 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/568768:Dpoa569_RS07190 ^@ http://purl.uniprot.org/uniprot/A0A5B8I519 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS03125 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2M6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/568768:Dpoa569_RS02080 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEU5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/568768:Dpoa569_RS13240 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNC6 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/568768:Dpoa569_RS13560 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/568768:Dpoa569_RS15485 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA79 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/568768:Dpoa569_RS09600 ^@ http://purl.uniprot.org/uniprot/A0A5B8IF83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS07710 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS17700 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJ61 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/568768:Dpoa569_RS07570 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBI4 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/568768:Dpoa569_RS12270 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA33 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/568768:Dpoa569_RS19065 ^@ http://purl.uniprot.org/uniprot/A0A5B8HT91 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS12650 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDE7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/568768:Dpoa569_RS12105 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9Z9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS07650 ^@ http://purl.uniprot.org/uniprot/A0A5B8HTY8 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/568768:Dpoa569_RS10350 ^@ http://purl.uniprot.org/uniprot/A0A5B8I726 ^@ Similarity ^@ Belongs to the UPF0265 family. http://togogenome.org/gene/568768:Dpoa569_RS02010 ^@ http://purl.uniprot.org/uniprot/A0A5B8HZR9 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/568768:Dpoa569_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6A0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.|||May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA. http://togogenome.org/gene/568768:Dpoa569_RS19310 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS14855 ^@ http://purl.uniprot.org/uniprot/A0A5B8HT23 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS04275 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1G4 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/568768:Dpoa569_RS03990 ^@ http://purl.uniprot.org/uniprot/A0A5B8HG66 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS08980 ^@ http://purl.uniprot.org/uniprot/A0A5B8HLZ2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16190 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICP2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/568768:Dpoa569_RS02990 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 1 family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS08090 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5F8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS19350 ^@ http://purl.uniprot.org/uniprot/A0A5B8IKT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 83 family.|||Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS05925 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8W3 ^@ Cofactor|||Function ^@ Binds 4 [4Fe-4S] clusters per subunit.|||The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. http://togogenome.org/gene/568768:Dpoa569_RS06870 ^@ http://purl.uniprot.org/uniprot/A0A5B8HI64 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 24 family. http://togogenome.org/gene/568768:Dpoa569_RS09610 ^@ http://purl.uniprot.org/uniprot/A0A5B8I898 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/568768:Dpoa569_RS11640 ^@ http://purl.uniprot.org/uniprot/A0A5B8HP24 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS04045 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHU0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS09540 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSU0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell membrane|||Membrane|||Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter. http://togogenome.org/gene/568768:Dpoa569_RS08275 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS04660 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5C4 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/568768:Dpoa569_RS17215 ^@ http://purl.uniprot.org/uniprot/A0A5B8HT29 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/568768:Dpoa569_RS01805 ^@ http://purl.uniprot.org/uniprot/A0A5B8HG05 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS17250 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA46 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/568768:Dpoa569_RS08280 ^@ http://purl.uniprot.org/uniprot/A0A5B8HL47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS02945 ^@ http://purl.uniprot.org/uniprot/A0A5B8I279 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/568768:Dpoa569_RS14870 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRL3 ^@ Function|||Similarity ^@ Belongs to the FrsA family.|||Catalyzes the hydrolysis of esters. http://togogenome.org/gene/568768:Dpoa569_RS01480 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS18050 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBG5 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/568768:Dpoa569_RS17725 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraB family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.|||Interacts with the C-terminal region of Rne. http://togogenome.org/gene/568768:Dpoa569_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1S0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/568768:Dpoa569_RS07025 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEU1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhC family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers. http://togogenome.org/gene/568768:Dpoa569_RS13870 ^@ http://purl.uniprot.org/uniprot/A0A5B8IG84 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS15815 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAR4 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/568768:Dpoa569_RS03080 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Membrane|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/568768:Dpoa569_RS02595 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6E7 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/568768:Dpoa569_RS05990 ^@ http://purl.uniprot.org/uniprot/A0A5B8I639 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/568768:Dpoa569_RS18320 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRL0 ^@ Similarity ^@ Belongs to the MreC family. http://togogenome.org/gene/568768:Dpoa569_RS01455 ^@ http://purl.uniprot.org/uniprot/A0A5B8I647 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/568768:Dpoa569_RS19335 ^@ http://purl.uniprot.org/uniprot/A0A5B8IKQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family.|||Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS04350 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7M1 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/568768:Dpoa569_RS07470 ^@ http://purl.uniprot.org/uniprot/A0A5B8I573 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS10840 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNG1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/568768:Dpoa569_RS10325 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN40 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS03485 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0U9 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/568768:Dpoa569_RS08565 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4C8 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/568768:Dpoa569_RS10980 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNL5 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/568768:Dpoa569_RS13460 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAW6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane|||The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains. http://togogenome.org/gene/568768:Dpoa569_RS07020 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKD7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhD family.|||Cytoplasm|||Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.|||The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA. http://togogenome.org/gene/568768:Dpoa569_RS14070 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS07430 ^@ http://purl.uniprot.org/uniprot/A0A5B8I570 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/568768:Dpoa569_RS17195 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/568768:Dpoa569_RS02710 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGM2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/568768:Dpoa569_RS16645 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSQ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/568768:Dpoa569_RS01665 ^@ http://purl.uniprot.org/uniprot/A0A5B8I691 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS03930 ^@ http://purl.uniprot.org/uniprot/A0A5B8I311 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS01915 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Secreted http://togogenome.org/gene/568768:Dpoa569_RS00990 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFC4 ^@ Similarity|||Subunit ^@ Homotetramer.|||In the C-terminal section; belongs to the homoserine dehydrogenase family.|||In the N-terminal section; belongs to the aspartokinase family. http://togogenome.org/gene/568768:Dpoa569_RS01475 ^@ http://purl.uniprot.org/uniprot/A0A5B8I108 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/568768:Dpoa569_RS05680 ^@ http://purl.uniprot.org/uniprot/A0A5B8I468 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS12755 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAD0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS07440 ^@ http://purl.uniprot.org/uniprot/A0A5B8HIM2 ^@ Function|||Similarity ^@ Belongs to the DUF177 domain family.|||Plays a role in synthesis, processing and/or stability of 23S rRNA. http://togogenome.org/gene/568768:Dpoa569_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8L1 ^@ Cofactor ^@ Binds 1 phosphopantetheine covalently. http://togogenome.org/gene/568768:Dpoa569_RS05460 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3W4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS00460 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0C0 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/568768:Dpoa569_RS14915 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPL8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methylthioribose kinase family.|||Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS11255 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS17855 ^@ http://purl.uniprot.org/uniprot/A0A5B8IJC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/568768:Dpoa569_RS05555 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJI0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M74 family.|||Binds 2 Zn(2+) ions per subunit. Zn(2+) ion 1 is bound in the active site. Zn(2+) ion 2 is bound at the dimer interface by residues from both subunits.|||Dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS10235 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDI6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the PHP family.|||Binds 3 Zn(2+) ions per subunit.|||Homotrimer. http://togogenome.org/gene/568768:Dpoa569_RS11085 ^@ http://purl.uniprot.org/uniprot/A0A5B8HLK8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/568768:Dpoa569_RS15160 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. http://togogenome.org/gene/568768:Dpoa569_RS07715 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKQ9 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the SsuD family.|||Catalyzes the desulfonation of aliphatic sulfonates.|||FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.|||Homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS01265 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFI4 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/568768:Dpoa569_RS09875 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS16005 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0257 family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS02125 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1N1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/568768:Dpoa569_RS12810 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8Z4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10885 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC70 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/568768:Dpoa569_RS12605 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAA1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/568768:Dpoa569_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A5B8HHN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10175 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8R6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/568768:Dpoa569_RS04125 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS14055 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9Q5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS04340 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dGTPase family. Type 1 subfamily.|||Homotetramer.|||dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs. http://togogenome.org/gene/568768:Dpoa569_RS02360 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1T7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS04040 ^@ http://purl.uniprot.org/uniprot/A0A5B8HG81 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.|||Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Binds 1 siroheme per subunit.|||Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. http://togogenome.org/gene/568768:Dpoa569_RS03900 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEX3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS11450 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7M6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MdcC family.|||Covalently binds the prosthetic group of malonate decarboxylase.|||Cytoplasm|||Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism. http://togogenome.org/gene/568768:Dpoa569_RS01500 ^@ http://purl.uniprot.org/uniprot/A0A5B8I113 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Involved in a late step of protoheme IX synthesis.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS05575 ^@ http://purl.uniprot.org/uniprot/A0A5B8I442 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/568768:Dpoa569_RS01875 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1B5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DamX family.|||Cell inner membrane|||Non-essential cell division protein.|||The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring. http://togogenome.org/gene/568768:Dpoa569_RS04110 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7F2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS10815 ^@ http://purl.uniprot.org/uniprot/A0A5B8HLC3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15910 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRJ9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/568768:Dpoa569_RS09245 ^@ http://purl.uniprot.org/uniprot/A0A5B8I659 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||Multifunctional regulator of fatty acid metabolism. http://togogenome.org/gene/568768:Dpoa569_RS04490 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7P4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS15720 ^@ http://purl.uniprot.org/uniprot/A0A5B8HS51 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/568768:Dpoa569_RS03860 ^@ http://purl.uniprot.org/uniprot/A0A5B8I156 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS08270 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5J6 ^@ Function|||Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family.|||Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. http://togogenome.org/gene/568768:Dpoa569_RS08610 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5Y1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/568768:Dpoa569_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/568768:Dpoa569_RS17320 ^@ http://purl.uniprot.org/uniprot/A0A5B8HT53 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS05815 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8Q2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS18125 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDV1 ^@ Similarity ^@ Belongs to the GST superfamily. HSP26 family. http://togogenome.org/gene/568768:Dpoa569_RS05715 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5Z4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homohexamer.|||In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the CobB/CobQ family.|||Involved in acetate metabolism.|||The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site. http://togogenome.org/gene/568768:Dpoa569_RS06050 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8Y6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/568768:Dpoa569_RS10900 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS03095 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0J2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/568768:Dpoa569_RS13880 ^@ http://purl.uniprot.org/uniprot/A0A5B8IF81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/568768:Dpoa569_RS18255 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBM4 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/568768:Dpoa569_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7W2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/568768:Dpoa569_RS02155 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6M5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/568768:Dpoa569_RS02420 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGF9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase. http://togogenome.org/gene/568768:Dpoa569_RS04270 ^@ http://purl.uniprot.org/uniprot/A0A5B8I389 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/568768:Dpoa569_RS09320 ^@ http://purl.uniprot.org/uniprot/A0A5B8IB52 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/568768:Dpoa569_RS05130 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGT8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS18565 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRR4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS00585 ^@ http://purl.uniprot.org/uniprot/A0A5B8HYP2 ^@ Function ^@ Required for maximal bacterial cellulose synthesis. http://togogenome.org/gene/568768:Dpoa569_RS15500 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9Y2 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/568768:Dpoa569_RS13415 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ49 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/568768:Dpoa569_RS08640 ^@ http://purl.uniprot.org/uniprot/A0A5B8ILG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS02245 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1U9 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/568768:Dpoa569_RS10145 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5A8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/568768:Dpoa569_RS07215 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDL7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliH family.|||Cytoplasm|||Needed for flagellar regrowth and assembly. http://togogenome.org/gene/568768:Dpoa569_RS12685 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8B9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/568768:Dpoa569_RS11995 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A5B8HI44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/568768:Dpoa569_RS00085 ^@ http://purl.uniprot.org/uniprot/A0A5B8HS97 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/568768:Dpoa569_RS05935 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJS2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS02685 ^@ http://purl.uniprot.org/uniprot/A0A5B8I220 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS16570 ^@ http://purl.uniprot.org/uniprot/A0A5B8IB91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/568768:Dpoa569_RS18775 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBZ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/568768:Dpoa569_RS11530 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS13825 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9A2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/568768:Dpoa569_RS11510 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Cdh family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS10430 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN72 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.|||Feedback inhibited by histidine. http://togogenome.org/gene/568768:Dpoa569_RS00995 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5I5 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/568768:Dpoa569_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A5B8I629 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS13285 ^@ http://purl.uniprot.org/uniprot/A0A5B8I8P8 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS17420 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS09345 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4R4 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/568768:Dpoa569_RS18190 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBW9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD). http://togogenome.org/gene/568768:Dpoa569_RS01685 ^@ http://purl.uniprot.org/uniprot/A0A5B8I168 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/568768:Dpoa569_RS04650 ^@ http://purl.uniprot.org/uniprot/A0A5B8HI99 ^@ Cofactor|||Function ^@ Binds 1 [2Fe-2S] cluster.|||Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. http://togogenome.org/gene/568768:Dpoa569_RS09755 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6T2 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/568768:Dpoa569_RS16820 ^@ http://purl.uniprot.org/uniprot/A0A5B8HST5 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/568768:Dpoa569_RS13135 ^@ http://purl.uniprot.org/uniprot/A0A5B8HN88 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.|||Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/568768:Dpoa569_RS05050 ^@ http://purl.uniprot.org/uniprot/A0A5B8HJ60 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/568768:Dpoa569_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0M8 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/568768:Dpoa569_RS05880 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAC8 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/568768:Dpoa569_RS09685 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6G9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/568768:Dpoa569_RS10535 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNB0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/568768:Dpoa569_RS00690 ^@ http://purl.uniprot.org/uniprot/A0A5B8HYS9 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/568768:Dpoa569_RS04470 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3E7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RseB family.|||Periplasm http://togogenome.org/gene/568768:Dpoa569_RS02530 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1Y0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS10765 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS12555 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA93 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/568768:Dpoa569_RS10485 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBY1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS05325 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3Z3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GSP I family.|||Cell inner membrane|||Cleaved by prepilin peptidase.|||Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.|||Membrane|||Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. http://togogenome.org/gene/568768:Dpoa569_RS00765 ^@ http://purl.uniprot.org/uniprot/A0A5B8ID84 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB). http://togogenome.org/gene/568768:Dpoa569_RS01260 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEA1 ^@ Similarity ^@ Belongs to the UPF0438 family. http://togogenome.org/gene/568768:Dpoa569_RS00755 ^@ http://purl.uniprot.org/uniprot/A0A5B8HE14 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/568768:Dpoa569_RS16525 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQK1 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/568768:Dpoa569_RS07640 ^@ http://purl.uniprot.org/uniprot/A0A5B8I5B7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LplA family.|||Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.|||Cytoplasm|||In the transfer reaction, the free carboxyl group of lipoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS08005 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAA2 ^@ Similarity ^@ Belongs to the aldolase class II family. AraD/FucA subfamily. http://togogenome.org/gene/568768:Dpoa569_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1V7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/568768:Dpoa569_RS08945 ^@ http://purl.uniprot.org/uniprot/A0A5B8HLY5 ^@ Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudJ subfamily.|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS08505 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC96 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ProQ family.|||Cytoplasm|||RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. http://togogenome.org/gene/568768:Dpoa569_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A5B8I830 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.|||Belongs to the RecC family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/568768:Dpoa569_RS10590 ^@ http://purl.uniprot.org/uniprot/A0A5B8IC10 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/568768:Dpoa569_RS15015 ^@ http://purl.uniprot.org/uniprot/A0A5B8HPP8 ^@ Similarity ^@ Belongs to the HipA Ser/Thr kinase family. http://togogenome.org/gene/568768:Dpoa569_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A5B8IBC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/568768:Dpoa569_RS13700 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9J2 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/568768:Dpoa569_RS02445 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6T9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/568768:Dpoa569_RS11165 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. RhlE subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA. http://togogenome.org/gene/568768:Dpoa569_RS02830 ^@ http://purl.uniprot.org/uniprot/A0A5B8I294 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/568768:Dpoa569_RS01560 ^@ http://purl.uniprot.org/uniprot/A0A5B8I669 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07140 ^@ http://purl.uniprot.org/uniprot/A0A5B8I508 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/568768:Dpoa569_RS10605 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDR7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS13805 ^@ http://purl.uniprot.org/uniprot/A0A5B8IE77 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/568768:Dpoa569_RS06935 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKB3 ^@ Function|||Similarity ^@ Belongs to the phage GPA family.|||Possible endonuclease which induces a single-strand cut and initiates DNA replication. http://togogenome.org/gene/568768:Dpoa569_RS12715 ^@ http://purl.uniprot.org/uniprot/A0A5B8IF92 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/568768:Dpoa569_RS04290 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. http://togogenome.org/gene/568768:Dpoa569_RS01645 ^@ http://purl.uniprot.org/uniprot/A0A5B8HFW6 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/568768:Dpoa569_RS15630 ^@ http://purl.uniprot.org/uniprot/A0A5B8IHL4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZipA family.|||Cell inner membrane|||Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.|||Interacts with FtsZ via their C-terminal domains. http://togogenome.org/gene/568768:Dpoa569_RS02470 ^@ http://purl.uniprot.org/uniprot/A0A5B8HF27 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/568768:Dpoa569_RS01075 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS16540 ^@ http://purl.uniprot.org/uniprot/A0A5B8II53 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cell membrane|||Homodimer.|||May be involved in cell division. http://togogenome.org/gene/568768:Dpoa569_RS04680 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1Q5 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/568768:Dpoa569_RS11580 ^@ http://purl.uniprot.org/uniprot/A0A5B8ICQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS02385 ^@ http://purl.uniprot.org/uniprot/A0A5B8HEX0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the calycin superfamily. Lipocalin family.|||Cell outer membrane|||Homodimer.|||Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids. http://togogenome.org/gene/568768:Dpoa569_RS07900 ^@ http://purl.uniprot.org/uniprot/A0A5B8I772 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/568768:Dpoa569_RS04620 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3H0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.|||Cell membrane|||Efflux system for nickel and cobalt.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15830 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQ50 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/568768:Dpoa569_RS16420 ^@ http://purl.uniprot.org/uniprot/A0A5B8II32 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/568768:Dpoa569_RS14805 ^@ http://purl.uniprot.org/uniprot/A0A5B8IEV4 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/568768:Dpoa569_RS04280 ^@ http://purl.uniprot.org/uniprot/A0A5B8I3A8 ^@ Function|||Similarity ^@ Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/568768:Dpoa569_RS19275 ^@ http://purl.uniprot.org/uniprot/A0A5B8HUG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS07325 ^@ http://purl.uniprot.org/uniprot/A0A5B8I500 ^@ Function|||Similarity ^@ Belongs to the GMC oxidoreductase family.|||Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. http://togogenome.org/gene/568768:Dpoa569_RS17060 ^@ http://purl.uniprot.org/uniprot/A0A5B8IB71 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/568768:Dpoa569_RS09120 ^@ http://purl.uniprot.org/uniprot/A0A5B8I4L4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/568768:Dpoa569_RS14040 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9E6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS11900 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6E3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS02040 ^@ http://purl.uniprot.org/uniprot/A0A5B8I1K1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DsrF/TusC family.|||Cytoplasm|||Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. http://togogenome.org/gene/568768:Dpoa569_RS15390 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS12960 ^@ http://purl.uniprot.org/uniprot/A0A5B8IFI7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M20A family. DapE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS03640 ^@ http://purl.uniprot.org/uniprot/A0A5B8I2U2 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/568768:Dpoa569_RS01255 ^@ http://purl.uniprot.org/uniprot/A0A5B8I0V2 ^@ Function|||Similarity ^@ Belongs to the LysR transcriptional regulatory family.|||Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon. http://togogenome.org/gene/568768:Dpoa569_RS15525 ^@ http://purl.uniprot.org/uniprot/A0A5B8HRD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/568768:Dpoa569_RS10185 ^@ http://purl.uniprot.org/uniprot/A0A5B8IDH3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/568768:Dpoa569_RS07385 ^@ http://purl.uniprot.org/uniprot/A0A5B8HKB9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family.|||Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).|||Cell inner membrane http://togogenome.org/gene/568768:Dpoa569_RS16575 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAN2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/568768:Dpoa569_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGA7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/568768:Dpoa569_RS12640 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMT8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b560 family.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/568768:Dpoa569_RS14440 ^@ http://purl.uniprot.org/uniprot/A0A5B8I9C9 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/568768:Dpoa569_RS13375 ^@ http://purl.uniprot.org/uniprot/A0A5B8I927 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/568768:Dpoa569_RS12690 ^@ http://purl.uniprot.org/uniprot/A0A5B8HMV3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/568768:Dpoa569_RS19170 ^@ http://purl.uniprot.org/uniprot/A0A5B8HS35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial glucokinase family.|||Cytoplasm http://togogenome.org/gene/568768:Dpoa569_RS15650 ^@ http://purl.uniprot.org/uniprot/A0A5B8IA17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/568768:Dpoa569_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A5B8HGU7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.|||Homodimer. http://togogenome.org/gene/568768:Dpoa569_RS11155 ^@ http://purl.uniprot.org/uniprot/A0A5B8HNP7 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusC subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. http://togogenome.org/gene/568768:Dpoa569_RS16815 ^@ http://purl.uniprot.org/uniprot/A0A5B8HQQ6 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/568768:Dpoa569_RS10915 ^@ http://purl.uniprot.org/uniprot/A0A5B8I7B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/568768:Dpoa569_RS15985 ^@ http://purl.uniprot.org/uniprot/A0A5B8IAB7 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/568768:Dpoa569_RS16870 ^@ http://purl.uniprot.org/uniprot/A0A5B8HSV1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane|||Responsible for the transport of C4-dicarboxylates. http://togogenome.org/gene/568768:Dpoa569_RS07230 ^@ http://purl.uniprot.org/uniprot/A0A5B8I6S8 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family.