http://togogenome.org/gene/573413:SPIRS_RS09690 ^@ http://purl.uniprot.org/uniprot/E1R6M3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/573413:SPIRS_RS14590 ^@ http://purl.uniprot.org/uniprot/E1R3M1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/573413:SPIRS_RS03700 ^@ http://purl.uniprot.org/uniprot/E1RBY6 ^@ Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family. http://togogenome.org/gene/573413:SPIRS_RS05705 ^@ http://purl.uniprot.org/uniprot/E1R114 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS18455 ^@ http://purl.uniprot.org/uniprot/E1R7N9 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/573413:SPIRS_RS13245 ^@ http://purl.uniprot.org/uniprot/E1R4J2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS00405 ^@ http://purl.uniprot.org/uniprot/E1R899 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/573413:SPIRS_RS00950 ^@ http://purl.uniprot.org/uniprot/E1R8K0 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/573413:SPIRS_RS04510 ^@ http://purl.uniprot.org/uniprot/E1RCE6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS20735 ^@ http://purl.uniprot.org/uniprot/E1R9N0 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/573413:SPIRS_RS02860 ^@ http://purl.uniprot.org/uniprot/E1RBH8 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/573413:SPIRS_RS17175 ^@ http://purl.uniprot.org/uniprot/E1R2D2 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/573413:SPIRS_RS10360 ^@ http://purl.uniprot.org/uniprot/E1R2Y6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS20745 ^@ http://purl.uniprot.org/uniprot/E1R9N2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS19850 ^@ http://purl.uniprot.org/uniprot/E1R955 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS00930 ^@ http://purl.uniprot.org/uniprot/E1R8J6 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/573413:SPIRS_RS20755 ^@ http://purl.uniprot.org/uniprot/E1R9N4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/573413:SPIRS_RS14375 ^@ http://purl.uniprot.org/uniprot/E1R264 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MCH family.|||Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS09680 ^@ http://purl.uniprot.org/uniprot/E1R6M1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/573413:SPIRS_RS15380 ^@ http://purl.uniprot.org/uniprot/E1R4R0 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/573413:SPIRS_RS15410 ^@ http://purl.uniprot.org/uniprot/E1R4R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS03895 ^@ http://purl.uniprot.org/uniprot/E1RC26 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/573413:SPIRS_RS21420 ^@ http://purl.uniprot.org/uniprot/E1RA13 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS08215 ^@ http://purl.uniprot.org/uniprot/E1R5Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS16770 ^@ http://purl.uniprot.org/uniprot/E1RAQ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS20840 ^@ http://purl.uniprot.org/uniprot/E1R9Q1 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/573413:SPIRS_RS10185 ^@ http://purl.uniprot.org/uniprot/E1R1J6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/573413:SPIRS_RS11100 ^@ http://purl.uniprot.org/uniprot/E1R6Y8 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/573413:SPIRS_RS04840 ^@ http://purl.uniprot.org/uniprot/E1RCL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/573413:SPIRS_RS12025 ^@ http://purl.uniprot.org/uniprot/E1R1X2 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/573413:SPIRS_RS10515 ^@ http://purl.uniprot.org/uniprot/E1R316 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/573413:SPIRS_RS16130 ^@ http://purl.uniprot.org/uniprot/E1R5G9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/573413:SPIRS_RS07070 ^@ http://purl.uniprot.org/uniprot/E1R4A5 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/573413:SPIRS_RS21345 ^@ http://purl.uniprot.org/uniprot/E1R9Z8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS21990 ^@ http://purl.uniprot.org/uniprot/E1R3J5 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/573413:SPIRS_RS08530 ^@ http://purl.uniprot.org/uniprot/E1R649 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/573413:SPIRS_RS08000 ^@ http://purl.uniprot.org/uniprot/E1R5U3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/573413:SPIRS_RS10260 ^@ http://purl.uniprot.org/uniprot/E1R1L1 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/573413:SPIRS_RS12820 ^@ http://purl.uniprot.org/uniprot/E1R4A9 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/573413:SPIRS_RS03740 ^@ http://purl.uniprot.org/uniprot/E1RBZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS20400 ^@ http://purl.uniprot.org/uniprot/E1R9G3 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/573413:SPIRS_RS21155 ^@ http://purl.uniprot.org/uniprot/E1R9W2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS00055 ^@ http://purl.uniprot.org/uniprot/E1R6P0 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/573413:SPIRS_RS15375 ^@ http://purl.uniprot.org/uniprot/E1R4Q9 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/573413:SPIRS_RS13130 ^@ http://purl.uniprot.org/uniprot/E1R4G9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FliD family.|||Homopentamer.|||Periplasm|||Periplasmic flagellum|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. http://togogenome.org/gene/573413:SPIRS_RS13360 ^@ http://purl.uniprot.org/uniprot/E1R4L3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS08290 ^@ http://purl.uniprot.org/uniprot/E1R602 ^@ Cofactor ^@ Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/573413:SPIRS_RS18650 ^@ http://purl.uniprot.org/uniprot/E1R7S9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell inner membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS05630 ^@ http://purl.uniprot.org/uniprot/E1R100 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS03960 ^@ http://purl.uniprot.org/uniprot/E1RC39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS15755 ^@ http://purl.uniprot.org/uniprot/E1R4Y3 ^@ Caution|||Function|||Similarity ^@ Belongs to the GARS family.|||Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||In the C-terminal section; belongs to the GART family.|||In the central section; belongs to the AIR synthase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS00230 ^@ http://purl.uniprot.org/uniprot/E1R6S5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/573413:SPIRS_RS16205 ^@ http://purl.uniprot.org/uniprot/E1R5I4 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/573413:SPIRS_RS19225 ^@ http://purl.uniprot.org/uniprot/E1R844 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/573413:SPIRS_RS18150 ^@ http://purl.uniprot.org/uniprot/E1R7I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS03455 ^@ http://purl.uniprot.org/uniprot/E1RBU1 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/573413:SPIRS_RS16625 ^@ http://purl.uniprot.org/uniprot/E1RAM1 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/573413:SPIRS_RS15190 ^@ http://purl.uniprot.org/uniprot/E1R3Y9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Homodimer.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.|||The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.|||The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity. http://togogenome.org/gene/573413:SPIRS_RS11585 ^@ http://purl.uniprot.org/uniprot/E1R1N7 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/573413:SPIRS_RS11605 ^@ http://purl.uniprot.org/uniprot/E1R1P1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TER reductase family.|||Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS13085 ^@ http://purl.uniprot.org/uniprot/E1R4G0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/573413:SPIRS_RS08360 ^@ http://purl.uniprot.org/uniprot/E1R616 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/573413:SPIRS_RS04335 ^@ http://purl.uniprot.org/uniprot/E1RCB4 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/573413:SPIRS_RS07450 ^@ http://purl.uniprot.org/uniprot/E1R568 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/573413:SPIRS_RS07490 ^@ http://purl.uniprot.org/uniprot/E1R576 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS09170 ^@ http://purl.uniprot.org/uniprot/E1R6C0 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/573413:SPIRS_RS19380 ^@ http://purl.uniprot.org/uniprot/E1R876 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS03555 ^@ http://purl.uniprot.org/uniprot/E1RBV7 ^@ Function|||Similarity ^@ Belongs to the PemK/MazF family.|||Toxic component of a type II toxin-antitoxin (TA) system. http://togogenome.org/gene/573413:SPIRS_RS09455 ^@ http://purl.uniprot.org/uniprot/E1R6H5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RNase HII family.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/573413:SPIRS_RS17980 ^@ http://purl.uniprot.org/uniprot/E1R7E7 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/573413:SPIRS_RS15845 ^@ http://purl.uniprot.org/uniprot/E1R5B1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS15970 ^@ http://purl.uniprot.org/uniprot/E1R5D6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/573413:SPIRS_RS10280 ^@ http://purl.uniprot.org/uniprot/E1R1L5 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/573413:SPIRS_RS20585 ^@ http://purl.uniprot.org/uniprot/E1R9K0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/573413:SPIRS_RS21500 ^@ http://purl.uniprot.org/uniprot/E1RA28 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS00220 ^@ http://purl.uniprot.org/uniprot/E1R6S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS05495 ^@ http://purl.uniprot.org/uniprot/E1R0X3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.|||Cell inner membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Requires K(+) for maximal activity.|||Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. http://togogenome.org/gene/573413:SPIRS_RS09135 ^@ http://purl.uniprot.org/uniprot/E1R6B3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS02995 ^@ http://purl.uniprot.org/uniprot/E1RBK6 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/573413:SPIRS_RS15320 ^@ http://purl.uniprot.org/uniprot/E1R4P8 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/573413:SPIRS_RS10485 ^@ http://purl.uniprot.org/uniprot/E1R311 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS04105 ^@ http://purl.uniprot.org/uniprot/E1RC68 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/573413:SPIRS_RS06455 ^@ http://purl.uniprot.org/uniprot/E1R2X8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS08210 ^@ http://purl.uniprot.org/uniprot/E1R5Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS21870 ^@ http://purl.uniprot.org/uniprot/E1RAL2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS11150 ^@ http://purl.uniprot.org/uniprot/E1R6Z8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS00015 ^@ http://purl.uniprot.org/uniprot/E1R6N2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/573413:SPIRS_RS06835 ^@ http://purl.uniprot.org/uniprot/E1R458 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS05955 ^@ http://purl.uniprot.org/uniprot/E1R2N0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS00890 ^@ http://purl.uniprot.org/uniprot/E1R8I9 ^@ Similarity ^@ Belongs to the CobT family. http://togogenome.org/gene/573413:SPIRS_RS08420 ^@ http://purl.uniprot.org/uniprot/E1R627 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS18210 ^@ http://purl.uniprot.org/uniprot/E1R7J2 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/573413:SPIRS_RS10845 ^@ http://purl.uniprot.org/uniprot/E1R380 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS02420 ^@ http://purl.uniprot.org/uniprot/E1RB94 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/573413:SPIRS_RS16025 ^@ http://purl.uniprot.org/uniprot/E1R5E8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/573413:SPIRS_RS16285 ^@ http://purl.uniprot.org/uniprot/E1R5J5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS00795 ^@ http://purl.uniprot.org/uniprot/E1R8H0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell inner membrane http://togogenome.org/gene/573413:SPIRS_RS01320 ^@ http://purl.uniprot.org/uniprot/E1RAC6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS17020 ^@ http://purl.uniprot.org/uniprot/E1R2A3 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/573413:SPIRS_RS11775 ^@ http://purl.uniprot.org/uniprot/E1R1S3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS10255 ^@ http://purl.uniprot.org/uniprot/E1R1L0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/573413:SPIRS_RS15765 ^@ http://purl.uniprot.org/uniprot/E1R4Y5 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/573413:SPIRS_RS18275 ^@ http://purl.uniprot.org/uniprot/E1R7K3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Membrane|||Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/573413:SPIRS_RS21150 ^@ http://purl.uniprot.org/uniprot/E1R9W1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS17850 ^@ http://purl.uniprot.org/uniprot/E1R7C1 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/573413:SPIRS_RS19275 ^@ http://purl.uniprot.org/uniprot/E1R855 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS15870 ^@ http://purl.uniprot.org/uniprot/E1R5B6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS15535 ^@ http://purl.uniprot.org/uniprot/E1R4T9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS18575 ^@ http://purl.uniprot.org/uniprot/E1R7R4 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/573413:SPIRS_RS17455 ^@ http://purl.uniprot.org/uniprot/E1R2I7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system. http://togogenome.org/gene/573413:SPIRS_RS18255 ^@ http://purl.uniprot.org/uniprot/E1R7K0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/573413:SPIRS_RS15770 ^@ http://purl.uniprot.org/uniprot/E1R4Y6 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/573413:SPIRS_RS14520 ^@ http://purl.uniprot.org/uniprot/E1R293 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/573413:SPIRS_RS16920 ^@ http://purl.uniprot.org/uniprot/E1RAS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS00680 ^@ http://purl.uniprot.org/uniprot/E1R8E7 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/573413:SPIRS_RS17110 ^@ http://purl.uniprot.org/uniprot/E1R2C1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS04795 ^@ http://purl.uniprot.org/uniprot/E1RCK1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/573413:SPIRS_RS08475 ^@ http://purl.uniprot.org/uniprot/E1R638 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS00410 ^@ http://purl.uniprot.org/uniprot/E1R8A0 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/573413:SPIRS_RS03755 ^@ http://purl.uniprot.org/uniprot/E1RBZ7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS13300 ^@ http://purl.uniprot.org/uniprot/E1R4K1 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/573413:SPIRS_RS09855 ^@ http://purl.uniprot.org/uniprot/E1R1D3 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/573413:SPIRS_RS08260 ^@ http://purl.uniprot.org/uniprot/E1R5Z6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Membrane|||Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/573413:SPIRS_RS09435 ^@ http://purl.uniprot.org/uniprot/E1R6H2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Membrane|||Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/573413:SPIRS_RS00225 ^@ http://purl.uniprot.org/uniprot/E1R6S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS16430 ^@ http://purl.uniprot.org/uniprot/E1RAI5 ^@ Function|||Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.|||Catalyzes the biosynthesis of agmatine from arginine. http://togogenome.org/gene/573413:SPIRS_RS06585 ^@ http://purl.uniprot.org/uniprot/E1R408 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/573413:SPIRS_RS01195 ^@ http://purl.uniprot.org/uniprot/E1RAA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS04815 ^@ http://purl.uniprot.org/uniprot/E1RCK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/573413:SPIRS_RS11515 ^@ http://purl.uniprot.org/uniprot/E1R772 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/573413:SPIRS_RS07840 ^@ http://purl.uniprot.org/uniprot/E1R5R1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS12005 ^@ http://purl.uniprot.org/uniprot/E1R1W8 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/573413:SPIRS_RS00270 ^@ http://purl.uniprot.org/uniprot/E1R6T3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS08660 ^@ http://purl.uniprot.org/uniprot/E1R675 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/573413:SPIRS_RS09090 ^@ http://purl.uniprot.org/uniprot/E1R1A4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS02500 ^@ http://purl.uniprot.org/uniprot/E1RBB0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS14535 ^@ http://purl.uniprot.org/uniprot/E1R296 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/573413:SPIRS_RS06725 ^@ http://purl.uniprot.org/uniprot/E1R436 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/573413:SPIRS_RS05470 ^@ http://purl.uniprot.org/uniprot/E1R0W8 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/573413:SPIRS_RS01375 ^@ http://purl.uniprot.org/uniprot/E1RAD7 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/573413:SPIRS_RS19490 ^@ http://purl.uniprot.org/uniprot/E1R8Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS04545 ^@ http://purl.uniprot.org/uniprot/E1RCF3 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/573413:SPIRS_RS15430 ^@ http://purl.uniprot.org/uniprot/E1R4R9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS16650 ^@ http://purl.uniprot.org/uniprot/E1RAM6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/573413:SPIRS_RS17395 ^@ http://purl.uniprot.org/uniprot/E1R2H6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS07750 ^@ http://purl.uniprot.org/uniprot/E1R5P3 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/573413:SPIRS_RS21475 ^@ http://purl.uniprot.org/uniprot/E1RA24 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS13970 ^@ http://purl.uniprot.org/uniprot/E1R8W4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS21220 ^@ http://purl.uniprot.org/uniprot/E1R9X5 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/573413:SPIRS_RS20860 ^@ http://purl.uniprot.org/uniprot/E1R9Q5 ^@ Cofactor|||Similarity ^@ Belongs to the alkaline phosphatase family.|||Binds 1 Mg(2+) ion.|||Binds 2 Zn(2+) ions. http://togogenome.org/gene/573413:SPIRS_RS05890 ^@ http://purl.uniprot.org/uniprot/E1R150 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS14605 ^@ http://purl.uniprot.org/uniprot/E1R3M4 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/573413:SPIRS_RS05390 ^@ http://purl.uniprot.org/uniprot/E1R0V4 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/573413:SPIRS_RS07970 ^@ http://purl.uniprot.org/uniprot/E1R5T7 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS05415 ^@ http://purl.uniprot.org/uniprot/E1R0V9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/573413:SPIRS_RS07880 ^@ http://purl.uniprot.org/uniprot/E1R5R9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/573413:SPIRS_RS18060 ^@ http://purl.uniprot.org/uniprot/E1R7G2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS15670 ^@ http://purl.uniprot.org/uniprot/E1R4W6 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/573413:SPIRS_RS03685 ^@ http://purl.uniprot.org/uniprot/E1RBY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS18625 ^@ http://purl.uniprot.org/uniprot/E1R7S4 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/573413:SPIRS_RS03445 ^@ http://purl.uniprot.org/uniprot/E1RBT9 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/573413:SPIRS_RS00145 ^@ http://purl.uniprot.org/uniprot/E1R6Q8 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/573413:SPIRS_RS05030 ^@ http://purl.uniprot.org/uniprot/E1RCQ0 ^@ Similarity ^@ Belongs to the aldolase class II family. AraD/FucA subfamily. http://togogenome.org/gene/573413:SPIRS_RS06845 ^@ http://purl.uniprot.org/uniprot/E1R460 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/573413:SPIRS_RS08130 ^@ http://purl.uniprot.org/uniprot/E1R5X0 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/573413:SPIRS_RS17505 ^@ http://purl.uniprot.org/uniprot/E1R2J7 ^@ Similarity ^@ Belongs to the UPF0166 family. http://togogenome.org/gene/573413:SPIRS_RS09665 ^@ http://purl.uniprot.org/uniprot/E1R6L8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/573413:SPIRS_RS05320 ^@ http://purl.uniprot.org/uniprot/E1R0T9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS18770 ^@ http://purl.uniprot.org/uniprot/E1R7V3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS13415 ^@ http://purl.uniprot.org/uniprot/E1R4M2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS07300 ^@ http://purl.uniprot.org/uniprot/E1R538 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/573413:SPIRS_RS16255 ^@ http://purl.uniprot.org/uniprot/E1R5J3 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/573413:SPIRS_RS17985 ^@ http://purl.uniprot.org/uniprot/E1R7E8 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/573413:SPIRS_RS09910 ^@ http://purl.uniprot.org/uniprot/E1R1E3 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/573413:SPIRS_RS17595 ^@ http://purl.uniprot.org/uniprot/E1R2L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS21570 ^@ http://purl.uniprot.org/uniprot/E1RA42 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/573413:SPIRS_RS14825 ^@ http://purl.uniprot.org/uniprot/E1R3R7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS20885 ^@ http://purl.uniprot.org/uniprot/E1R9R0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS19075 ^@ http://purl.uniprot.org/uniprot/E1R814 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS09915 ^@ http://purl.uniprot.org/uniprot/E1R1E4 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/573413:SPIRS_RS02470 ^@ http://purl.uniprot.org/uniprot/E1RBA4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/573413:SPIRS_RS04025 ^@ http://purl.uniprot.org/uniprot/E1RC52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS08125 ^@ http://purl.uniprot.org/uniprot/E1R5W9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS12410 ^@ http://purl.uniprot.org/uniprot/E1R3E0 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/573413:SPIRS_RS18660 ^@ http://purl.uniprot.org/uniprot/E1R7T1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS16970 ^@ http://purl.uniprot.org/uniprot/E1RAT7 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/573413:SPIRS_RS04955 ^@ http://purl.uniprot.org/uniprot/E1RCN5 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/573413:SPIRS_RS18385 ^@ http://purl.uniprot.org/uniprot/E1R7M5 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS16735 ^@ http://purl.uniprot.org/uniprot/E1RAP3 ^@ Similarity ^@ Belongs to the peptidase C69 family. http://togogenome.org/gene/573413:SPIRS_RS15690 ^@ http://purl.uniprot.org/uniprot/E1R4X0 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/573413:SPIRS_RS20195 ^@ http://purl.uniprot.org/uniprot/E1R9C4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS05020 ^@ http://purl.uniprot.org/uniprot/E1RCP8 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS00425 ^@ http://purl.uniprot.org/uniprot/E1R8A3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/573413:SPIRS_RS12310 ^@ http://purl.uniprot.org/uniprot/E1R3C0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/573413:SPIRS_RS18380 ^@ http://purl.uniprot.org/uniprot/E1R7M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS21120 ^@ http://purl.uniprot.org/uniprot/E1R9V5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS19180 ^@ http://purl.uniprot.org/uniprot/E1R835 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/573413:SPIRS_RS08965 ^@ http://purl.uniprot.org/uniprot/E1R180 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS15915 ^@ http://purl.uniprot.org/uniprot/E1R5C4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS05050 ^@ http://purl.uniprot.org/uniprot/E1RCQ4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/573413:SPIRS_RS14705 ^@ http://purl.uniprot.org/uniprot/E1R3P4 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/573413:SPIRS_RS06700 ^@ http://purl.uniprot.org/uniprot/E1R431 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/573413:SPIRS_RS07140 ^@ http://purl.uniprot.org/uniprot/E1R506 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS09050 ^@ http://purl.uniprot.org/uniprot/E1R196 ^@ Similarity|||Subunit ^@ Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/573413:SPIRS_RS08500 ^@ http://purl.uniprot.org/uniprot/E1R643 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS20685 ^@ http://purl.uniprot.org/uniprot/E1R9M1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/573413:SPIRS_RS10290 ^@ http://purl.uniprot.org/uniprot/E1R1L7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS15130 ^@ http://purl.uniprot.org/uniprot/E1R3X7 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/573413:SPIRS_RS06595 ^@ http://purl.uniprot.org/uniprot/E1R410 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS10475 ^@ http://purl.uniprot.org/uniprot/E1R309 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS07380 ^@ http://purl.uniprot.org/uniprot/E1R554 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/573413:SPIRS_RS02785 ^@ http://purl.uniprot.org/uniprot/E1RBG3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/573413:SPIRS_RS03385 ^@ http://purl.uniprot.org/uniprot/E1RBS8 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/573413:SPIRS_RS05360 ^@ http://purl.uniprot.org/uniprot/E1R0U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS04850 ^@ http://purl.uniprot.org/uniprot/E1RCL2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/573413:SPIRS_RS11615 ^@ http://purl.uniprot.org/uniprot/E1R1P3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS21470 ^@ http://purl.uniprot.org/uniprot/E1RA23 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS17060 ^@ http://purl.uniprot.org/uniprot/E1R2B2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS10890 ^@ http://purl.uniprot.org/uniprot/E1R389 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS02615 ^@ http://purl.uniprot.org/uniprot/E1RBD1 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/573413:SPIRS_RS09130 ^@ http://purl.uniprot.org/uniprot/E1R6B2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/573413:SPIRS_RS03780 ^@ http://purl.uniprot.org/uniprot/E1RC02 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/573413:SPIRS_RS16505 ^@ http://purl.uniprot.org/uniprot/E1RAJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS02295 ^@ http://purl.uniprot.org/uniprot/E1RB69 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/573413:SPIRS_RS13165 ^@ http://purl.uniprot.org/uniprot/E1R4H6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/573413:SPIRS_RS11835 ^@ http://purl.uniprot.org/uniprot/E1R1T4 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/573413:SPIRS_RS21645 ^@ http://purl.uniprot.org/uniprot/E1RA57 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/573413:SPIRS_RS01340 ^@ http://purl.uniprot.org/uniprot/E1RAD0 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS13680 ^@ http://purl.uniprot.org/uniprot/E1R8Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS12190 ^@ http://purl.uniprot.org/uniprot/E1R396 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS15820 ^@ http://purl.uniprot.org/uniprot/E1R5A6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/573413:SPIRS_RS14610 ^@ http://purl.uniprot.org/uniprot/E1R3M5 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS01730 ^@ http://purl.uniprot.org/uniprot/E1RAW8 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/573413:SPIRS_RS12455 ^@ http://purl.uniprot.org/uniprot/E1R3E9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/573413:SPIRS_RS04835 ^@ http://purl.uniprot.org/uniprot/E1RCK9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/573413:SPIRS_RS06235 ^@ http://purl.uniprot.org/uniprot/E1R2T4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system. http://togogenome.org/gene/573413:SPIRS_RS13030 ^@ http://purl.uniprot.org/uniprot/E1R4E9 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/573413:SPIRS_RS17450 ^@ http://purl.uniprot.org/uniprot/E1R2I6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS18680 ^@ http://purl.uniprot.org/uniprot/E1R7T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein SsuA/TauA family.|||Periplasm http://togogenome.org/gene/573413:SPIRS_RS01360 ^@ http://purl.uniprot.org/uniprot/E1RAD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS05930 ^@ http://purl.uniprot.org/uniprot/E1R2M5 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS09195 ^@ http://purl.uniprot.org/uniprot/E1R6C4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/573413:SPIRS_RS14350 ^@ http://purl.uniprot.org/uniprot/E1R259 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS07410 ^@ http://purl.uniprot.org/uniprot/E1R560 ^@ Function|||Similarity ^@ Belongs to the ferredoxin thioredoxin reductase beta subunit family.|||Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin. http://togogenome.org/gene/573413:SPIRS_RS16820 ^@ http://purl.uniprot.org/uniprot/E1RAR0 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/573413:SPIRS_RS01435 ^@ http://purl.uniprot.org/uniprot/E1RAE9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS02555 ^@ http://purl.uniprot.org/uniprot/E1RBC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS16460 ^@ http://purl.uniprot.org/uniprot/E1RAJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS05865 ^@ http://purl.uniprot.org/uniprot/E1R145 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS02800 ^@ http://purl.uniprot.org/uniprot/E1RBG6 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/573413:SPIRS_RS08045 ^@ http://purl.uniprot.org/uniprot/E1R5V2 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/573413:SPIRS_RS12415 ^@ http://purl.uniprot.org/uniprot/E1R3E1 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/573413:SPIRS_RS21460 ^@ http://purl.uniprot.org/uniprot/E1RA21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS03280 ^@ http://purl.uniprot.org/uniprot/E1RBQ9 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/573413:SPIRS_RS08400 ^@ http://purl.uniprot.org/uniprot/E1R623 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/573413:SPIRS_RS00855 ^@ http://purl.uniprot.org/uniprot/E1R8I2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/573413:SPIRS_RS16715 ^@ http://purl.uniprot.org/uniprot/E1RAN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS20075 ^@ http://purl.uniprot.org/uniprot/E1R9A0 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/573413:SPIRS_RS06515 ^@ http://purl.uniprot.org/uniprot/E1R3Z9 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/573413:SPIRS_RS06345 ^@ http://purl.uniprot.org/uniprot/E1R2V6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/573413:SPIRS_RS02220 ^@ http://purl.uniprot.org/uniprot/E1RB55 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/573413:SPIRS_RS15315 ^@ http://purl.uniprot.org/uniprot/E1R4P7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS04935 ^@ http://purl.uniprot.org/uniprot/E1RCN1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/573413:SPIRS_RS06315 ^@ http://purl.uniprot.org/uniprot/E1R2V0 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/573413:SPIRS_RS14995 ^@ http://purl.uniprot.org/uniprot/E1R3V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS13175 ^@ http://purl.uniprot.org/uniprot/E1R4H8 ^@ Function|||Subcellular Location Annotation ^@ Component of the core of the flagella.|||Periplasmic flagellum http://togogenome.org/gene/573413:SPIRS_RS17770 ^@ http://purl.uniprot.org/uniprot/E1R7A5 ^@ Cofactor|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily.|||Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/573413:SPIRS_RS06035 ^@ http://purl.uniprot.org/uniprot/E1R2P6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS17425 ^@ http://purl.uniprot.org/uniprot/E1R2I2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS00525 ^@ http://purl.uniprot.org/uniprot/E1R8B8 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/573413:SPIRS_RS14560 ^@ http://purl.uniprot.org/uniprot/E1R2A1 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/573413:SPIRS_RS04205 ^@ http://purl.uniprot.org/uniprot/E1RC89 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS00985 ^@ http://purl.uniprot.org/uniprot/E1R8K6 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/573413:SPIRS_RS06440 ^@ http://purl.uniprot.org/uniprot/E1R2X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS14540 ^@ http://purl.uniprot.org/uniprot/E1R297 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/573413:SPIRS_RS18130 ^@ http://purl.uniprot.org/uniprot/E1R7H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS17370 ^@ http://purl.uniprot.org/uniprot/E1R2H1 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/573413:SPIRS_RS08325 ^@ http://purl.uniprot.org/uniprot/E1R609 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/573413:SPIRS_RS10805 ^@ http://purl.uniprot.org/uniprot/E1R372 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS00935 ^@ http://purl.uniprot.org/uniprot/E1R8J7 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/573413:SPIRS_RS06275 ^@ http://purl.uniprot.org/uniprot/E1R2U2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS08690 ^@ http://purl.uniprot.org/uniprot/E1R681 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS16935 ^@ http://purl.uniprot.org/uniprot/E1RAT1 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/573413:SPIRS_RS17815 ^@ http://purl.uniprot.org/uniprot/E1R7B4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS21355 ^@ http://purl.uniprot.org/uniprot/E1RA00 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/573413:SPIRS_RS05925 ^@ http://purl.uniprot.org/uniprot/E1R2M4 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/573413:SPIRS_RS16745 ^@ http://purl.uniprot.org/uniprot/E1RAP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS10715 ^@ http://purl.uniprot.org/uniprot/E1R354 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/573413:SPIRS_RS07525 ^@ http://purl.uniprot.org/uniprot/E1R583 ^@ Similarity ^@ Belongs to the TrpR family. http://togogenome.org/gene/573413:SPIRS_RS11315 ^@ http://purl.uniprot.org/uniprot/E1R732 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/573413:SPIRS_RS12095 ^@ http://purl.uniprot.org/uniprot/E1R1Y2 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/573413:SPIRS_RS10720 ^@ http://purl.uniprot.org/uniprot/E1R355 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS21090 ^@ http://purl.uniprot.org/uniprot/E1R9V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS13890 ^@ http://purl.uniprot.org/uniprot/E1R8U9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/573413:SPIRS_RS01365 ^@ http://purl.uniprot.org/uniprot/E1RAD5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/573413:SPIRS_RS15565 ^@ http://purl.uniprot.org/uniprot/E1R4U6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS15305 ^@ http://purl.uniprot.org/uniprot/E1R4P5 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/573413:SPIRS_RS12855 ^@ http://purl.uniprot.org/uniprot/E1R4B6 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/573413:SPIRS_RS17485 ^@ http://purl.uniprot.org/uniprot/E1R2J3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/573413:SPIRS_RS05580 ^@ http://purl.uniprot.org/uniprot/E1R0Z0 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/573413:SPIRS_RS03030 ^@ http://purl.uniprot.org/uniprot/E1RBL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/573413:SPIRS_RS04645 ^@ http://purl.uniprot.org/uniprot/E1RCH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS01505 ^@ http://purl.uniprot.org/uniprot/E1RAG3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS13955 ^@ http://purl.uniprot.org/uniprot/E1R8W1 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/573413:SPIRS_RS09635 ^@ http://purl.uniprot.org/uniprot/E1R6L2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS20750 ^@ http://purl.uniprot.org/uniprot/E1R9N3 ^@ Function|||Similarity ^@ Belongs to the TrpF family.|||Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.|||In the C-terminal section; belongs to the TrpF family.|||In the N-terminal section; belongs to the TrpC family. http://togogenome.org/gene/573413:SPIRS_RS19840 ^@ http://purl.uniprot.org/uniprot/E1R953 ^@ Similarity ^@ Belongs to the phosphopentomutase family. http://togogenome.org/gene/573413:SPIRS_RS17855 ^@ http://purl.uniprot.org/uniprot/E1R7C2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS04985 ^@ http://purl.uniprot.org/uniprot/E1RCP1 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/573413:SPIRS_RS11265 ^@ http://purl.uniprot.org/uniprot/E1R721 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS17025 ^@ http://purl.uniprot.org/uniprot/E1R2A4 ^@ Similarity ^@ Belongs to the YoeB family. http://togogenome.org/gene/573413:SPIRS_RS16015 ^@ http://purl.uniprot.org/uniprot/E1R5E6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS04905 ^@ http://purl.uniprot.org/uniprot/E1RCM4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/573413:SPIRS_RS19160 ^@ http://purl.uniprot.org/uniprot/E1R831 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/573413:SPIRS_RS14530 ^@ http://purl.uniprot.org/uniprot/E1R295 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/573413:SPIRS_RS05310 ^@ http://purl.uniprot.org/uniprot/E1R0T7 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/573413:SPIRS_RS00675 ^@ http://purl.uniprot.org/uniprot/E1R8E6 ^@ Similarity|||Subunit ^@ Belongs to the beta-eliminating lyase family.|||Homotetramer. http://togogenome.org/gene/573413:SPIRS_RS12200 ^@ http://purl.uniprot.org/uniprot/E1R398 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/573413:SPIRS_RS06590 ^@ http://purl.uniprot.org/uniprot/E1R409 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS10245 ^@ http://purl.uniprot.org/uniprot/E1R1K8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/573413:SPIRS_RS17440 ^@ http://purl.uniprot.org/uniprot/E1R2I4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS21630 ^@ http://purl.uniprot.org/uniprot/E1RA54 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/573413:SPIRS_RS06815 ^@ http://purl.uniprot.org/uniprot/E1R454 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/573413:SPIRS_RS15880 ^@ http://purl.uniprot.org/uniprot/E1R5B8 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS10785 ^@ http://purl.uniprot.org/uniprot/E1R368 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/573413:SPIRS_RS01675 ^@ http://purl.uniprot.org/uniprot/E1RAV7 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/573413:SPIRS_RS04825 ^@ http://purl.uniprot.org/uniprot/E1RCK7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/573413:SPIRS_RS08355 ^@ http://purl.uniprot.org/uniprot/E1R615 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/573413:SPIRS_RS05870 ^@ http://purl.uniprot.org/uniprot/E1R146 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS14635 ^@ http://purl.uniprot.org/uniprot/E1R3N0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/573413:SPIRS_RS09480 ^@ http://purl.uniprot.org/uniprot/E1R6I0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/573413:SPIRS_RS18220 ^@ http://purl.uniprot.org/uniprot/E1R7J4 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/573413:SPIRS_RS04500 ^@ http://purl.uniprot.org/uniprot/E1RCE4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 65 family. http://togogenome.org/gene/573413:SPIRS_RS19005 ^@ http://purl.uniprot.org/uniprot/E1R801 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS16305 ^@ http://purl.uniprot.org/uniprot/E1R5J9 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS13465 ^@ http://purl.uniprot.org/uniprot/E1R8L6 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/573413:SPIRS_RS02460 ^@ http://purl.uniprot.org/uniprot/E1RBA2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/573413:SPIRS_RS00820 ^@ http://purl.uniprot.org/uniprot/E1R8H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS08010 ^@ http://purl.uniprot.org/uniprot/E1R5U5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Cell membrane|||Membrane|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/573413:SPIRS_RS07065 ^@ http://purl.uniprot.org/uniprot/E1R4A4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/573413:SPIRS_RS15360 ^@ http://purl.uniprot.org/uniprot/E1R4Q5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS15460 ^@ http://purl.uniprot.org/uniprot/E1R4S5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS13445 ^@ http://purl.uniprot.org/uniprot/E1R8L2 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/573413:SPIRS_RS08315 ^@ http://purl.uniprot.org/uniprot/E1R607 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS12255 ^@ http://purl.uniprot.org/uniprot/E1R3A9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS16145 ^@ http://purl.uniprot.org/uniprot/E1R5H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/573413:SPIRS_RS12835 ^@ http://purl.uniprot.org/uniprot/E1R4B2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/573413:SPIRS_RS15060 ^@ http://purl.uniprot.org/uniprot/E1R3W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS10435 ^@ http://purl.uniprot.org/uniprot/E1R301 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS05790 ^@ http://purl.uniprot.org/uniprot/E1R131 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/573413:SPIRS_RS04470 ^@ http://purl.uniprot.org/uniprot/E1RCD8 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/573413:SPIRS_RS17400 ^@ http://purl.uniprot.org/uniprot/E1R2H7 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/573413:SPIRS_RS18620 ^@ http://purl.uniprot.org/uniprot/E1R7S3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/573413:SPIRS_RS17925 ^@ http://purl.uniprot.org/uniprot/E1R7D6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/573413:SPIRS_RS08005 ^@ http://purl.uniprot.org/uniprot/E1R5U4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/573413:SPIRS_RS15900 ^@ http://purl.uniprot.org/uniprot/E1R5C1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS04805 ^@ http://purl.uniprot.org/uniprot/E1RCK3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/573413:SPIRS_RS05155 ^@ http://purl.uniprot.org/uniprot/E1RCS5 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/573413:SPIRS_RS04145 ^@ http://purl.uniprot.org/uniprot/E1RC76 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS12090 ^@ http://purl.uniprot.org/uniprot/E1R1Y1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS06150 ^@ http://purl.uniprot.org/uniprot/E1R2R7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS12000 ^@ http://purl.uniprot.org/uniprot/E1R1W7 ^@ Function ^@ Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate. http://togogenome.org/gene/573413:SPIRS_RS10575 ^@ http://purl.uniprot.org/uniprot/E1R326 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS05145 ^@ http://purl.uniprot.org/uniprot/E1RCS3 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/573413:SPIRS_RS02830 ^@ http://purl.uniprot.org/uniprot/E1RBH2 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/573413:SPIRS_RS02445 ^@ http://purl.uniprot.org/uniprot/E1RB99 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/573413:SPIRS_RS04695 ^@ http://purl.uniprot.org/uniprot/E1RCI3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/573413:SPIRS_RS15175 ^@ http://purl.uniprot.org/uniprot/E1R3Y6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/573413:SPIRS_RS18495 ^@ http://purl.uniprot.org/uniprot/E1R7P7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/573413:SPIRS_RS11395 ^@ http://purl.uniprot.org/uniprot/E1R748 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS04265 ^@ http://purl.uniprot.org/uniprot/E1RCA0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS12350 ^@ http://purl.uniprot.org/uniprot/E1R3C8 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS09150 ^@ http://purl.uniprot.org/uniprot/E1R6B6 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/573413:SPIRS_RS13180 ^@ http://purl.uniprot.org/uniprot/E1R4H9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/573413:SPIRS_RS02795 ^@ http://purl.uniprot.org/uniprot/E1RBG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS01850 ^@ http://purl.uniprot.org/uniprot/E1RAZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS15170 ^@ http://purl.uniprot.org/uniprot/E1R3Y5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Binds 1 [8Fe-7S] cluster per heterodimer.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/573413:SPIRS_RS01180 ^@ http://purl.uniprot.org/uniprot/E1RA99 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/573413:SPIRS_RS13990 ^@ http://purl.uniprot.org/uniprot/E1R8W8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/573413:SPIRS_RS10175 ^@ http://purl.uniprot.org/uniprot/E1R1J4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/573413:SPIRS_RS07355 ^@ http://purl.uniprot.org/uniprot/E1R549 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/573413:SPIRS_RS09185 ^@ http://purl.uniprot.org/uniprot/E1R6C2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/573413:SPIRS_RS12270 ^@ http://purl.uniprot.org/uniprot/E1R3B2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS15225 ^@ http://purl.uniprot.org/uniprot/E1R4M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS19655 ^@ http://purl.uniprot.org/uniprot/E1R916 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/573413:SPIRS_RS12450 ^@ http://purl.uniprot.org/uniprot/E1R3E8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS18790 ^@ http://purl.uniprot.org/uniprot/E1R7V8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS20080 ^@ http://purl.uniprot.org/uniprot/E1R9A1 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/573413:SPIRS_RS17630 ^@ http://purl.uniprot.org/uniprot/E1R777 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS04945 ^@ http://purl.uniprot.org/uniprot/E1RCN3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/573413:SPIRS_RS02440 ^@ http://purl.uniprot.org/uniprot/E1RB98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS08910 ^@ http://purl.uniprot.org/uniprot/E1R169 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/573413:SPIRS_RS14115 ^@ http://purl.uniprot.org/uniprot/E1R210 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/573413:SPIRS_RS16810 ^@ http://purl.uniprot.org/uniprot/E1RAQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS06785 ^@ http://purl.uniprot.org/uniprot/E1R448 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/573413:SPIRS_RS03025 ^@ http://purl.uniprot.org/uniprot/E1RBL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS12100 ^@ http://purl.uniprot.org/uniprot/E1R1Y3 ^@ Similarity|||Subunit ^@ Belongs to the methylthioribose kinase family.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS13255 ^@ http://purl.uniprot.org/uniprot/E1R4J4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/573413:SPIRS_RS18740 ^@ http://purl.uniprot.org/uniprot/E1R7U7 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/573413:SPIRS_RS13490 ^@ http://purl.uniprot.org/uniprot/E1R8M1 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/573413:SPIRS_RS07905 ^@ http://purl.uniprot.org/uniprot/E1R5S4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/573413:SPIRS_RS11105 ^@ http://purl.uniprot.org/uniprot/E1R6Y9 ^@ Similarity ^@ Belongs to the YoeB family. http://togogenome.org/gene/573413:SPIRS_RS09550 ^@ http://purl.uniprot.org/uniprot/E1R6J5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/573413:SPIRS_RS15390 ^@ http://purl.uniprot.org/uniprot/E1R4R2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS07135 ^@ http://purl.uniprot.org/uniprot/E1R505 ^@ Similarity ^@ Belongs to the acetyltransferase family. ArgA subfamily. http://togogenome.org/gene/573413:SPIRS_RS05860 ^@ http://purl.uniprot.org/uniprot/E1R144 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/573413:SPIRS_RS19520 ^@ http://purl.uniprot.org/uniprot/E1R8Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS12335 ^@ http://purl.uniprot.org/uniprot/E1R3C5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS03625 ^@ http://purl.uniprot.org/uniprot/E1RBX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS07055 ^@ http://purl.uniprot.org/uniprot/E1R4A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS04225 ^@ http://purl.uniprot.org/uniprot/E1RC93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS15070 ^@ http://purl.uniprot.org/uniprot/E1R3W5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/573413:SPIRS_RS11550 ^@ http://purl.uniprot.org/uniprot/E1R1N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS15575 ^@ http://purl.uniprot.org/uniprot/E1R4U8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/573413:SPIRS_RS04925 ^@ http://purl.uniprot.org/uniprot/E1RCM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/573413:SPIRS_RS08595 ^@ http://purl.uniprot.org/uniprot/E1R662 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS21180 ^@ http://purl.uniprot.org/uniprot/E1R9W7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/573413:SPIRS_RS16065 ^@ http://purl.uniprot.org/uniprot/E1R5F6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/573413:SPIRS_RS02415 ^@ http://purl.uniprot.org/uniprot/E1RB93 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/573413:SPIRS_RS02980 ^@ http://purl.uniprot.org/uniprot/E1RBK3 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/573413:SPIRS_RS06485 ^@ http://purl.uniprot.org/uniprot/E1R3Z3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M3B family.|||Binds 1 zinc ion.|||Has oligopeptidase activity and degrades a variety of small bioactive peptides. http://togogenome.org/gene/573413:SPIRS_RS08435 ^@ http://purl.uniprot.org/uniprot/E1R630 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/573413:SPIRS_RS06055 ^@ http://purl.uniprot.org/uniprot/E1R2Q0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LPG synthase family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS06330 ^@ http://purl.uniprot.org/uniprot/E1R2V3 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/573413:SPIRS_RS19870 ^@ http://purl.uniprot.org/uniprot/E1R959 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/573413:SPIRS_RS06070 ^@ http://purl.uniprot.org/uniprot/E1R2Q3 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/573413:SPIRS_RS13080 ^@ http://purl.uniprot.org/uniprot/E1R4F9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS20050 ^@ http://purl.uniprot.org/uniprot/E1R995 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/573413:SPIRS_RS07110 ^@ http://purl.uniprot.org/uniprot/E1R500 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/573413:SPIRS_RS20390 ^@ http://purl.uniprot.org/uniprot/E1R9G1 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/573413:SPIRS_RS03915 ^@ http://purl.uniprot.org/uniprot/E1RC30 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/573413:SPIRS_RS16565 ^@ http://purl.uniprot.org/uniprot/E1RAL1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS19090 ^@ http://purl.uniprot.org/uniprot/E1R817 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/573413:SPIRS_RS05750 ^@ http://purl.uniprot.org/uniprot/E1R123 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/573413:SPIRS_RS14880 ^@ http://purl.uniprot.org/uniprot/E1R3S8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS04785 ^@ http://purl.uniprot.org/uniprot/E1RCJ9 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/573413:SPIRS_RS21660 ^@ http://purl.uniprot.org/uniprot/E1RA60 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/573413:SPIRS_RS04585 ^@ http://purl.uniprot.org/uniprot/E1RCG1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS18475 ^@ http://purl.uniprot.org/uniprot/E1R7P3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS06650 ^@ http://purl.uniprot.org/uniprot/E1R421 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/573413:SPIRS_RS01285 ^@ http://purl.uniprot.org/uniprot/E1RAB9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS01900 ^@ http://purl.uniprot.org/uniprot/E1RB02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS18360 ^@ http://purl.uniprot.org/uniprot/E1R7M0 ^@ Cofactor ^@ Binds 2 magnesium ions per subunit. http://togogenome.org/gene/573413:SPIRS_RS05850 ^@ http://purl.uniprot.org/uniprot/E1R142 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/573413:SPIRS_RS16815 ^@ http://purl.uniprot.org/uniprot/E1RAQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS12165 ^@ http://purl.uniprot.org/uniprot/E1R1Z6 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/573413:SPIRS_RS08815 ^@ http://purl.uniprot.org/uniprot/E1R6A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS15700 ^@ http://purl.uniprot.org/uniprot/E1R4X2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS10600 ^@ http://purl.uniprot.org/uniprot/E1R331 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/573413:SPIRS_RS00330 ^@ http://purl.uniprot.org/uniprot/E1R6U5 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/573413:SPIRS_RS06120 ^@ http://purl.uniprot.org/uniprot/E1R2R1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/573413:SPIRS_RS05525 ^@ http://purl.uniprot.org/uniprot/E1R0X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS02815 ^@ http://purl.uniprot.org/uniprot/E1RBG9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS20495 ^@ http://purl.uniprot.org/uniprot/E1R9I2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Membrane|||Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/573413:SPIRS_RS15840 ^@ http://purl.uniprot.org/uniprot/E1R5B0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.|||This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. http://togogenome.org/gene/573413:SPIRS_RS12075 ^@ http://purl.uniprot.org/uniprot/E1R1X8 ^@ Similarity ^@ Belongs to the Rpn/YhgA-like nuclease family. http://togogenome.org/gene/573413:SPIRS_RS17525 ^@ http://purl.uniprot.org/uniprot/E1R2K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS00035 ^@ http://purl.uniprot.org/uniprot/E1R6N6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell inner membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/573413:SPIRS_RS18195 ^@ http://purl.uniprot.org/uniprot/E1R7I9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS20135 ^@ http://purl.uniprot.org/uniprot/E1R9B2 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/573413:SPIRS_RS17845 ^@ http://purl.uniprot.org/uniprot/E1R7C0 ^@ Similarity ^@ Belongs to the CarB family. http://togogenome.org/gene/573413:SPIRS_RS06280 ^@ http://purl.uniprot.org/uniprot/E1R2U3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS06750 ^@ http://purl.uniprot.org/uniprot/E1R441 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/573413:SPIRS_RS06905 ^@ http://purl.uniprot.org/uniprot/E1R472 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS10850 ^@ http://purl.uniprot.org/uniprot/E1R381 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/573413:SPIRS_RS17715 ^@ http://purl.uniprot.org/uniprot/E1R794 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/573413:SPIRS_RS02915 ^@ http://purl.uniprot.org/uniprot/E1RBI9 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/573413:SPIRS_RS09115 ^@ http://purl.uniprot.org/uniprot/E1R6A9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS18970 ^@ http://purl.uniprot.org/uniprot/E1R7Z4 ^@ Cofactor|||Similarity ^@ Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/573413:SPIRS_RS03365 ^@ http://purl.uniprot.org/uniprot/E1RBS4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/573413:SPIRS_RS16670 ^@ http://purl.uniprot.org/uniprot/E1RAN0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/573413:SPIRS_RS05990 ^@ http://purl.uniprot.org/uniprot/E1R2N7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS02490 ^@ http://purl.uniprot.org/uniprot/E1RBA8 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/573413:SPIRS_RS15685 ^@ http://purl.uniprot.org/uniprot/E1R4W9 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/573413:SPIRS_RS19565 ^@ http://purl.uniprot.org/uniprot/E1R8Z8 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/573413:SPIRS_RS15245 ^@ http://purl.uniprot.org/uniprot/E1R4N3 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/573413:SPIRS_RS00335 ^@ http://purl.uniprot.org/uniprot/E1R6U6 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/573413:SPIRS_RS16550 ^@ http://purl.uniprot.org/uniprot/E1RAK8 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/573413:SPIRS_RS18645 ^@ http://purl.uniprot.org/uniprot/E1R7S8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/573413:SPIRS_RS00830 ^@ http://purl.uniprot.org/uniprot/E1R8H7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/573413:SPIRS_RS07805 ^@ http://purl.uniprot.org/uniprot/E1R5Q4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/573413:SPIRS_RS19940 ^@ http://purl.uniprot.org/uniprot/E1R973 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS16470 ^@ http://purl.uniprot.org/uniprot/E1RAJ2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/573413:SPIRS_RS03840 ^@ http://purl.uniprot.org/uniprot/E1RC14 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS19215 ^@ http://purl.uniprot.org/uniprot/E1R842 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/573413:SPIRS_RS17500 ^@ http://purl.uniprot.org/uniprot/E1R2J6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell inner membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/573413:SPIRS_RS08225 ^@ http://purl.uniprot.org/uniprot/E1R5Y9 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/573413:SPIRS_RS21360 ^@ http://purl.uniprot.org/uniprot/E1RA01 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS06175 ^@ http://purl.uniprot.org/uniprot/E1R2S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS03645 ^@ http://purl.uniprot.org/uniprot/E1RBX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS16035 ^@ http://purl.uniprot.org/uniprot/E1R5F0 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/573413:SPIRS_RS17700 ^@ http://purl.uniprot.org/uniprot/E1R791 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/573413:SPIRS_RS08060 ^@ http://purl.uniprot.org/uniprot/E1R5V5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/573413:SPIRS_RS16390 ^@ http://purl.uniprot.org/uniprot/E1R5L6 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/573413:SPIRS_RS16345 ^@ http://purl.uniprot.org/uniprot/E1R5K7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell inner membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/573413:SPIRS_RS11595 ^@ http://purl.uniprot.org/uniprot/E1R1N9 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/573413:SPIRS_RS16500 ^@ http://purl.uniprot.org/uniprot/E1RAJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS04670 ^@ http://purl.uniprot.org/uniprot/E1RCH8 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS02675 ^@ http://purl.uniprot.org/uniprot/E1RBE3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS07370 ^@ http://purl.uniprot.org/uniprot/E1R552 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/573413:SPIRS_RS04865 ^@ http://purl.uniprot.org/uniprot/E1RCL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/573413:SPIRS_RS05120 ^@ http://purl.uniprot.org/uniprot/E1RCR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS04780 ^@ http://purl.uniprot.org/uniprot/E1RCJ8 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/573413:SPIRS_RS14700 ^@ http://purl.uniprot.org/uniprot/E1R3P3 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/573413:SPIRS_RS22335 ^@ http://purl.uniprot.org/uniprot/E1RCJ6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/573413:SPIRS_RS13090 ^@ http://purl.uniprot.org/uniprot/E1R4G1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/573413:SPIRS_RS04820 ^@ http://purl.uniprot.org/uniprot/E1RCK6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/573413:SPIRS_RS06050 ^@ http://purl.uniprot.org/uniprot/E1R2P9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/573413:SPIRS_RS15120 ^@ http://purl.uniprot.org/uniprot/E1R3X5 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/573413:SPIRS_RS04890 ^@ http://purl.uniprot.org/uniprot/E1RCM0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/573413:SPIRS_RS18920 ^@ http://purl.uniprot.org/uniprot/E1R7Y3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/573413:SPIRS_RS07890 ^@ http://purl.uniprot.org/uniprot/E1R5S1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/573413:SPIRS_RS08450 ^@ http://purl.uniprot.org/uniprot/E1R633 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/573413:SPIRS_RS14920 ^@ http://purl.uniprot.org/uniprot/E1R3T6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS02465 ^@ http://purl.uniprot.org/uniprot/E1RBA3 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/573413:SPIRS_RS08605 ^@ http://purl.uniprot.org/uniprot/E1R664 ^@ Function|||Similarity ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane. http://togogenome.org/gene/573413:SPIRS_RS03785 ^@ http://purl.uniprot.org/uniprot/E1RC03 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS07940 ^@ http://purl.uniprot.org/uniprot/E1R5T1 ^@ Similarity ^@ Belongs to the FlgD family. http://togogenome.org/gene/573413:SPIRS_RS13700 ^@ http://purl.uniprot.org/uniprot/E1R8R3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/573413:SPIRS_RS17775 ^@ http://purl.uniprot.org/uniprot/E1R7A6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS02695 ^@ http://purl.uniprot.org/uniprot/E1RBE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS11540 ^@ http://purl.uniprot.org/uniprot/E1R1M8 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/573413:SPIRS_RS15775 ^@ http://purl.uniprot.org/uniprot/E1R4Y7 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/573413:SPIRS_RS03205 ^@ http://purl.uniprot.org/uniprot/E1RBP4 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/573413:SPIRS_RS03265 ^@ http://purl.uniprot.org/uniprot/E1RBQ6 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/573413:SPIRS_RS10295 ^@ http://purl.uniprot.org/uniprot/E1R1L8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/573413:SPIRS_RS05270 ^@ http://purl.uniprot.org/uniprot/E1RCU8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS11400 ^@ http://purl.uniprot.org/uniprot/E1R749 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS07260 ^@ http://purl.uniprot.org/uniprot/E1R531 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/573413:SPIRS_RS16620 ^@ http://purl.uniprot.org/uniprot/E1RAM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS01560 ^@ http://purl.uniprot.org/uniprot/E1RAH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS07180 ^@ http://purl.uniprot.org/uniprot/E1R514 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/573413:SPIRS_RS05530 ^@ http://purl.uniprot.org/uniprot/E1R0Y0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS12805 ^@ http://purl.uniprot.org/uniprot/E1R4A6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS11340 ^@ http://purl.uniprot.org/uniprot/E1R737 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS04180 ^@ http://purl.uniprot.org/uniprot/E1RC84 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/573413:SPIRS_RS07870 ^@ http://purl.uniprot.org/uniprot/E1R5R7 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/573413:SPIRS_RS17475 ^@ http://purl.uniprot.org/uniprot/E1R2J1 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/573413:SPIRS_RS05365 ^@ http://purl.uniprot.org/uniprot/E1R0U8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS00515 ^@ http://purl.uniprot.org/uniprot/E1R8B6 ^@ Similarity ^@ Belongs to the thymidine kinase family. http://togogenome.org/gene/573413:SPIRS_RS01145 ^@ http://purl.uniprot.org/uniprot/E1RA92 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/573413:SPIRS_RS06555 ^@ http://purl.uniprot.org/uniprot/E1R402 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/573413:SPIRS_RS04895 ^@ http://purl.uniprot.org/uniprot/E1RCM1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/573413:SPIRS_RS20440 ^@ http://purl.uniprot.org/uniprot/E1R9H1 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS09255 ^@ http://purl.uniprot.org/uniprot/E1R6D6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/573413:SPIRS_RS07625 ^@ http://purl.uniprot.org/uniprot/E1R5M4 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/573413:SPIRS_RS04920 ^@ http://purl.uniprot.org/uniprot/E1RCM7 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/573413:SPIRS_RS02410 ^@ http://purl.uniprot.org/uniprot/E1RB92 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/573413:SPIRS_RS11580 ^@ http://purl.uniprot.org/uniprot/E1R1N6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/573413:SPIRS_RS03150 ^@ http://purl.uniprot.org/uniprot/E1RBN3 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/573413:SPIRS_RS18540 ^@ http://purl.uniprot.org/uniprot/E1R7Q6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS09060 ^@ http://purl.uniprot.org/uniprot/E1R198 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||Periplasm|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/573413:SPIRS_RS10180 ^@ http://purl.uniprot.org/uniprot/E1R1J5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS11575 ^@ http://purl.uniprot.org/uniprot/E1R1N5 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/573413:SPIRS_RS08960 ^@ http://purl.uniprot.org/uniprot/E1R179 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS04560 ^@ http://purl.uniprot.org/uniprot/E1RCF6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 100 family. http://togogenome.org/gene/573413:SPIRS_RS18295 ^@ http://purl.uniprot.org/uniprot/E1R7K7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS19300 ^@ http://purl.uniprot.org/uniprot/E1R860 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/573413:SPIRS_RS01785 ^@ http://purl.uniprot.org/uniprot/E1RAX9 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/573413:SPIRS_RS11700 ^@ http://purl.uniprot.org/uniprot/E1R1Q8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS21465 ^@ http://purl.uniprot.org/uniprot/E1RA22 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS10210 ^@ http://purl.uniprot.org/uniprot/E1R1K1 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/573413:SPIRS_RS04530 ^@ http://purl.uniprot.org/uniprot/E1RCF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS20670 ^@ http://purl.uniprot.org/uniprot/E1R9L8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer. http://togogenome.org/gene/573413:SPIRS_RS11500 ^@ http://purl.uniprot.org/uniprot/E1R769 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/573413:SPIRS_RS16155 ^@ http://purl.uniprot.org/uniprot/E1R5H4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS07960 ^@ http://purl.uniprot.org/uniprot/E1R5T5 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/573413:SPIRS_RS18750 ^@ http://purl.uniprot.org/uniprot/E1R7U9 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS05245 ^@ http://purl.uniprot.org/uniprot/E1RCU3 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/573413:SPIRS_RS21400 ^@ http://purl.uniprot.org/uniprot/E1RA09 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/573413:SPIRS_RS19245 ^@ http://purl.uniprot.org/uniprot/E1R849 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS06780 ^@ http://purl.uniprot.org/uniprot/E1R447 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/573413:SPIRS_RS05940 ^@ http://purl.uniprot.org/uniprot/E1R2M7 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/573413:SPIRS_RS07855 ^@ http://purl.uniprot.org/uniprot/E1R5R4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/573413:SPIRS_RS08585 ^@ http://purl.uniprot.org/uniprot/E1R660 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/573413:SPIRS_RS09080 ^@ http://purl.uniprot.org/uniprot/E1R1A2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/573413:SPIRS_RS20760 ^@ http://purl.uniprot.org/uniprot/E1R9N5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/573413:SPIRS_RS11270 ^@ http://purl.uniprot.org/uniprot/E1R722 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/573413:SPIRS_RS18655 ^@ http://purl.uniprot.org/uniprot/E1R7T0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS14425 ^@ http://purl.uniprot.org/uniprot/E1R274 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/573413:SPIRS_RS06005 ^@ http://purl.uniprot.org/uniprot/E1R2P0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0316 family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS00770 ^@ http://purl.uniprot.org/uniprot/E1R8G5 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/573413:SPIRS_RS10905 ^@ http://purl.uniprot.org/uniprot/E1R392 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/573413:SPIRS_RS10480 ^@ http://purl.uniprot.org/uniprot/E1R310 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/573413:SPIRS_RS11290 ^@ http://purl.uniprot.org/uniprot/E1R727 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS00920 ^@ http://purl.uniprot.org/uniprot/E1R8J4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS20405 ^@ http://purl.uniprot.org/uniprot/E1R9G4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS13915 ^@ http://purl.uniprot.org/uniprot/E1R8V4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/573413:SPIRS_RS04005 ^@ http://purl.uniprot.org/uniprot/E1RC48 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/573413:SPIRS_RS04680 ^@ http://purl.uniprot.org/uniprot/E1RCI0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/573413:SPIRS_RS09700 ^@ http://purl.uniprot.org/uniprot/E1R6M5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/573413:SPIRS_RS17200 ^@ http://purl.uniprot.org/uniprot/E1R2D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS10385 ^@ http://purl.uniprot.org/uniprot/E1R2Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS01485 ^@ http://purl.uniprot.org/uniprot/E1RAF9 ^@ Similarity ^@ Belongs to the WrbA family. http://togogenome.org/gene/573413:SPIRS_RS19580 ^@ http://purl.uniprot.org/uniprot/E1R901 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS01105 ^@ http://purl.uniprot.org/uniprot/E1RA84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS21300 ^@ http://purl.uniprot.org/uniprot/E1R9Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS10595 ^@ http://purl.uniprot.org/uniprot/E1R330 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/573413:SPIRS_RS09560 ^@ http://purl.uniprot.org/uniprot/E1R6J7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS02865 ^@ http://purl.uniprot.org/uniprot/E1RBH9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS10250 ^@ http://purl.uniprot.org/uniprot/E1R1K9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/573413:SPIRS_RS15735 ^@ http://purl.uniprot.org/uniprot/E1R4X9 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/573413:SPIRS_RS12160 ^@ http://purl.uniprot.org/uniprot/E1R1Z5 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/573413:SPIRS_RS14890 ^@ http://purl.uniprot.org/uniprot/E1R3T0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/573413:SPIRS_RS14400 ^@ http://purl.uniprot.org/uniprot/E1R269 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/573413:SPIRS_RS03525 ^@ http://purl.uniprot.org/uniprot/E1RBV3 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/573413:SPIRS_RS19360 ^@ http://purl.uniprot.org/uniprot/E1R872 ^@ Similarity ^@ Belongs to the LarC family. http://togogenome.org/gene/573413:SPIRS_RS00125 ^@ http://purl.uniprot.org/uniprot/E1R6Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS07885 ^@ http://purl.uniprot.org/uniprot/E1R5S0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS04915 ^@ http://purl.uniprot.org/uniprot/E1RCM6 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/573413:SPIRS_RS17315 ^@ http://purl.uniprot.org/uniprot/E1R2G0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the arabinose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of L-arabinose to L-ribulose. http://togogenome.org/gene/573413:SPIRS_RS18105 ^@ http://purl.uniprot.org/uniprot/E1R7H1 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/573413:SPIRS_RS05710 ^@ http://purl.uniprot.org/uniprot/E1R115 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS00900 ^@ http://purl.uniprot.org/uniprot/E1R8J1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS21505 ^@ http://purl.uniprot.org/uniprot/E1RA29 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/573413:SPIRS_RS05240 ^@ http://purl.uniprot.org/uniprot/E1RCU2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS14555 ^@ http://purl.uniprot.org/uniprot/E1R2A0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS17865 ^@ http://purl.uniprot.org/uniprot/E1R7C4 ^@ Activity Regulation|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/573413:SPIRS_RS13540 ^@ http://purl.uniprot.org/uniprot/E1R8N1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS06600 ^@ http://purl.uniprot.org/uniprot/E1R411 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS02670 ^@ http://purl.uniprot.org/uniprot/E1RBE2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/573413:SPIRS_RS20070 ^@ http://purl.uniprot.org/uniprot/E1R999 ^@ Similarity ^@ Belongs to the radical SAM superfamily. KamA family. http://togogenome.org/gene/573413:SPIRS_RS08520 ^@ http://purl.uniprot.org/uniprot/E1R647 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/573413:SPIRS_RS05745 ^@ http://purl.uniprot.org/uniprot/E1R122 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/573413:SPIRS_RS06520 ^@ http://purl.uniprot.org/uniprot/E1R400 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/573413:SPIRS_RS07425 ^@ http://purl.uniprot.org/uniprot/E1R563 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS18725 ^@ http://purl.uniprot.org/uniprot/E1R7U4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS07550 ^@ http://purl.uniprot.org/uniprot/E1R588 ^@ Similarity ^@ Belongs to the UPF0164 family. http://togogenome.org/gene/573413:SPIRS_RS07910 ^@ http://purl.uniprot.org/uniprot/E1R5S5 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS05280 ^@ http://purl.uniprot.org/uniprot/E1RCV0 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/573413:SPIRS_RS02535 ^@ http://purl.uniprot.org/uniprot/E1RBB7 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/573413:SPIRS_RS10885 ^@ http://purl.uniprot.org/uniprot/E1R388 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS14460 ^@ http://purl.uniprot.org/uniprot/E1R281 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/573413:SPIRS_RS08535 ^@ http://purl.uniprot.org/uniprot/E1R650 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/573413:SPIRS_RS01780 ^@ http://purl.uniprot.org/uniprot/E1RAX8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/573413:SPIRS_RS06730 ^@ http://purl.uniprot.org/uniprot/E1R437 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/573413:SPIRS_RS05075 ^@ http://purl.uniprot.org/uniprot/E1RCQ9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/573413:SPIRS_RS01075 ^@ http://purl.uniprot.org/uniprot/E1RA78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS13910 ^@ http://purl.uniprot.org/uniprot/E1R8V3 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/573413:SPIRS_RS10505 ^@ http://purl.uniprot.org/uniprot/E1R314 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/573413:SPIRS_RS17530 ^@ http://purl.uniprot.org/uniprot/E1R2K2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/573413:SPIRS_RS06405 ^@ http://purl.uniprot.org/uniprot/E1R2W8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS18200 ^@ http://purl.uniprot.org/uniprot/E1R7J0 ^@ Cofactor|||Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Binds 1 FAD per subunit.|||Binds 1 FMN covalently per subunit. http://togogenome.org/gene/573413:SPIRS_RS17935 ^@ http://purl.uniprot.org/uniprot/E1R7D8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/573413:SPIRS_RS09045 ^@ http://purl.uniprot.org/uniprot/E1R195 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/573413:SPIRS_RS00670 ^@ http://purl.uniprot.org/uniprot/E1R8E5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS03710 ^@ http://purl.uniprot.org/uniprot/E1RBY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS20610 ^@ http://purl.uniprot.org/uniprot/E1R9K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS15890 ^@ http://purl.uniprot.org/uniprot/E1R5B9 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/573413:SPIRS_RS19775 ^@ http://purl.uniprot.org/uniprot/E1R940 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS04465 ^@ http://purl.uniprot.org/uniprot/E1RCD7 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/573413:SPIRS_RS10200 ^@ http://purl.uniprot.org/uniprot/E1R1J9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/573413:SPIRS_RS04260 ^@ http://purl.uniprot.org/uniprot/E1RC99 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS05205 ^@ http://purl.uniprot.org/uniprot/E1RCT5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS05315 ^@ http://purl.uniprot.org/uniprot/E1R0T8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS10855 ^@ http://purl.uniprot.org/uniprot/E1R382 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/573413:SPIRS_RS07345 ^@ http://purl.uniprot.org/uniprot/E1R547 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/573413:SPIRS_RS17570 ^@ http://purl.uniprot.org/uniprot/E1R2L0 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/573413:SPIRS_RS02495 ^@ http://purl.uniprot.org/uniprot/E1RBA9 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/573413:SPIRS_RS00025 ^@ http://purl.uniprot.org/uniprot/E1R6N4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/573413:SPIRS_RS05410 ^@ http://purl.uniprot.org/uniprot/E1R0V8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/573413:SPIRS_RS00570 ^@ http://purl.uniprot.org/uniprot/E1R8C5 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/573413:SPIRS_RS19900 ^@ http://purl.uniprot.org/uniprot/E1R965 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS04830 ^@ http://purl.uniprot.org/uniprot/E1RCK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/573413:SPIRS_RS17665 ^@ http://purl.uniprot.org/uniprot/E1R784 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/573413:SPIRS_RS08120 ^@ http://purl.uniprot.org/uniprot/E1R5W8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS09520 ^@ http://purl.uniprot.org/uniprot/E1R6I8 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/573413:SPIRS_RS18270 ^@ http://purl.uniprot.org/uniprot/E1R7K2 ^@ Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family. http://togogenome.org/gene/573413:SPIRS_RS02620 ^@ http://purl.uniprot.org/uniprot/E1RBD2 ^@ Caution|||Function|||Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS07895 ^@ http://purl.uniprot.org/uniprot/E1R5S2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/573413:SPIRS_RS00045 ^@ http://purl.uniprot.org/uniprot/E1R6N8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/573413:SPIRS_RS12365 ^@ http://purl.uniprot.org/uniprot/E1R3D1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/573413:SPIRS_RS15615 ^@ http://purl.uniprot.org/uniprot/E1R4V6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS21450 ^@ http://purl.uniprot.org/uniprot/E1RA19 ^@ Similarity|||Subunit ^@ Belongs to the CMP-NeuNAc synthase family.|||Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/573413:SPIRS_RS20015 ^@ http://purl.uniprot.org/uniprot/E1R988 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS05670 ^@ http://purl.uniprot.org/uniprot/E1R108 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS10340 ^@ http://purl.uniprot.org/uniprot/E1R2Y2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/573413:SPIRS_RS20490 ^@ http://purl.uniprot.org/uniprot/E1R9I1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/573413:SPIRS_RS17465 ^@ http://purl.uniprot.org/uniprot/E1R2I9 ^@ Function|||Similarity ^@ Belongs to the UxaE family.|||Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA). http://togogenome.org/gene/573413:SPIRS_RS15180 ^@ http://purl.uniprot.org/uniprot/E1R3Y7 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/573413:SPIRS_RS10735 ^@ http://purl.uniprot.org/uniprot/E1R358 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/573413:SPIRS_RS19025 ^@ http://purl.uniprot.org/uniprot/E1R804 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS10275 ^@ http://purl.uniprot.org/uniprot/E1R1L4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/573413:SPIRS_RS12175 ^@ http://purl.uniprot.org/uniprot/E1R1Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS16325 ^@ http://purl.uniprot.org/uniprot/E1R5K3 ^@ Cofactor|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily.|||Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/573413:SPIRS_RS09545 ^@ http://purl.uniprot.org/uniprot/E1R6J4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/573413:SPIRS_RS14570 ^@ http://purl.uniprot.org/uniprot/E1R3L7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family. http://togogenome.org/gene/573413:SPIRS_RS04280 ^@ http://purl.uniprot.org/uniprot/E1RCA3 ^@ Cofactor|||Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Binds 1 FAD per subunit.|||Binds 1 FMN covalently per subunit. http://togogenome.org/gene/573413:SPIRS_RS14015 ^@ http://purl.uniprot.org/uniprot/E1R8X3 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/573413:SPIRS_RS09660 ^@ http://purl.uniprot.org/uniprot/E1R6L7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/573413:SPIRS_RS15675 ^@ http://purl.uniprot.org/uniprot/E1R4W7 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/573413:SPIRS_RS13070 ^@ http://purl.uniprot.org/uniprot/E1R4F7 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/573413:SPIRS_RS04960 ^@ http://purl.uniprot.org/uniprot/E1RCN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS09155 ^@ http://purl.uniprot.org/uniprot/E1R6B7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/573413:SPIRS_RS02790 ^@ http://purl.uniprot.org/uniprot/E1RBG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS12825 ^@ http://purl.uniprot.org/uniprot/E1R4B0 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS01100 ^@ http://purl.uniprot.org/uniprot/E1RA83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS18155 ^@ http://purl.uniprot.org/uniprot/E1R7I1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS11195 ^@ http://purl.uniprot.org/uniprot/E1R707 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS05060 ^@ http://purl.uniprot.org/uniprot/E1RCQ6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS10190 ^@ http://purl.uniprot.org/uniprot/E1R1J7 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/573413:SPIRS_RS11770 ^@ http://purl.uniprot.org/uniprot/E1R1S2 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/573413:SPIRS_RS09845 ^@ http://purl.uniprot.org/uniprot/E1R1D1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/573413:SPIRS_RS18615 ^@ http://purl.uniprot.org/uniprot/E1R7S2 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/573413:SPIRS_RS09315 ^@ http://purl.uniprot.org/uniprot/E1R6E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS11220 ^@ http://purl.uniprot.org/uniprot/E1R712 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS20485 ^@ http://purl.uniprot.org/uniprot/E1R9I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS11990 ^@ http://purl.uniprot.org/uniprot/E1R1W5 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/573413:SPIRS_RS05805 ^@ http://purl.uniprot.org/uniprot/E1R134 ^@ Function|||Similarity ^@ Belongs to the anhydro-N-acetylmuramic acid kinase family.|||Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/573413:SPIRS_RS11955 ^@ http://purl.uniprot.org/uniprot/E1R1V8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/573413:SPIRS_RS01415 ^@ http://purl.uniprot.org/uniprot/E1RAE5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/573413:SPIRS_RS13985 ^@ http://purl.uniprot.org/uniprot/E1R8W7 ^@ Similarity ^@ In the C-terminal section; belongs to the homoserine dehydrogenase family.|||In the N-terminal section; belongs to the aspartokinase family. http://togogenome.org/gene/573413:SPIRS_RS20845 ^@ http://purl.uniprot.org/uniprot/E1R9Q2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS13900 ^@ http://purl.uniprot.org/uniprot/E1R8V1 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/573413:SPIRS_RS08455 ^@ http://purl.uniprot.org/uniprot/E1R634 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS08335 ^@ http://purl.uniprot.org/uniprot/E1R611 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/573413:SPIRS_RS10775 ^@ http://purl.uniprot.org/uniprot/E1R366 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. C-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/573413:SPIRS_RS10800 ^@ http://purl.uniprot.org/uniprot/E1R371 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS13045 ^@ http://purl.uniprot.org/uniprot/E1R4F2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS12810 ^@ http://purl.uniprot.org/uniprot/E1R4A7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS14895 ^@ http://purl.uniprot.org/uniprot/E1R3T1 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/573413:SPIRS_RS18350 ^@ http://purl.uniprot.org/uniprot/E1R7L8 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/573413:SPIRS_RS13480 ^@ http://purl.uniprot.org/uniprot/E1R8L9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS10880 ^@ http://purl.uniprot.org/uniprot/E1R387 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/573413:SPIRS_RS19460 ^@ http://purl.uniprot.org/uniprot/E1R8X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS04930 ^@ http://purl.uniprot.org/uniprot/E1RCM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/573413:SPIRS_RS12460 ^@ http://purl.uniprot.org/uniprot/E1R3F0 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/573413:SPIRS_RS12420 ^@ http://purl.uniprot.org/uniprot/E1R3E2 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/573413:SPIRS_RS00520 ^@ http://purl.uniprot.org/uniprot/E1R8B7 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/573413:SPIRS_RS07990 ^@ http://purl.uniprot.org/uniprot/E1R5U1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/573413:SPIRS_RS02880 ^@ http://purl.uniprot.org/uniprot/E1RBI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS07720 ^@ http://purl.uniprot.org/uniprot/E1R5P1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS04810 ^@ http://purl.uniprot.org/uniprot/E1RCK4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/573413:SPIRS_RS17305 ^@ http://purl.uniprot.org/uniprot/E1R2F8 ^@ Similarity ^@ Belongs to the ribulokinase family. http://togogenome.org/gene/573413:SPIRS_RS05590 ^@ http://purl.uniprot.org/uniprot/E1R0Z2 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/573413:SPIRS_RS04250 ^@ http://purl.uniprot.org/uniprot/E1RC97 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/573413:SPIRS_RS17130 ^@ http://purl.uniprot.org/uniprot/E1R2C3 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/573413:SPIRS_RS19000 ^@ http://purl.uniprot.org/uniprot/E1R800 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS16245 ^@ http://purl.uniprot.org/uniprot/E1R5J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS15865 ^@ http://purl.uniprot.org/uniprot/E1R5B5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS00990 ^@ http://purl.uniprot.org/uniprot/E1R8K7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS12260 ^@ http://purl.uniprot.org/uniprot/E1R3B0 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/573413:SPIRS_RS10165 ^@ http://purl.uniprot.org/uniprot/E1R1J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS17830 ^@ http://purl.uniprot.org/uniprot/E1R7B7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS19590 ^@ http://purl.uniprot.org/uniprot/E1R903 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/573413:SPIRS_RS18115 ^@ http://purl.uniprot.org/uniprot/E1R7H3 ^@ Function ^@ Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/573413:SPIRS_RS10895 ^@ http://purl.uniprot.org/uniprot/E1R390 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS20890 ^@ http://purl.uniprot.org/uniprot/E1R9R1 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS21085 ^@ http://purl.uniprot.org/uniprot/E1R9V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS09565 ^@ http://purl.uniprot.org/uniprot/E1R6J8 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/573413:SPIRS_RS11980 ^@ http://purl.uniprot.org/uniprot/E1R1W3 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/573413:SPIRS_RS15815 ^@ http://purl.uniprot.org/uniprot/E1R5A5 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/573413:SPIRS_RS17870 ^@ http://purl.uniprot.org/uniprot/E1R7C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS03450 ^@ http://purl.uniprot.org/uniprot/E1RBU0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS06510 ^@ http://purl.uniprot.org/uniprot/E1R3Z8 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/573413:SPIRS_RS15205 ^@ http://purl.uniprot.org/uniprot/E1R4M5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/573413:SPIRS_RS21550 ^@ http://purl.uniprot.org/uniprot/E1RA38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS11275 ^@ http://purl.uniprot.org/uniprot/E1R723 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS11455 ^@ http://purl.uniprot.org/uniprot/E1R760 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS07040 ^@ http://purl.uniprot.org/uniprot/E1R499 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS09460 ^@ http://purl.uniprot.org/uniprot/E1R6H6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/573413:SPIRS_RS20640 ^@ http://purl.uniprot.org/uniprot/E1R9L1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/573413:SPIRS_RS03955 ^@ http://purl.uniprot.org/uniprot/E1RC38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS16240 ^@ http://purl.uniprot.org/uniprot/E1R5J0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS11545 ^@ http://purl.uniprot.org/uniprot/E1R1M9 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/573413:SPIRS_RS09720 ^@ http://purl.uniprot.org/uniprot/E1R1A6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/573413:SPIRS_RS12385 ^@ http://purl.uniprot.org/uniprot/E1R3D5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/573413:SPIRS_RS20225 ^@ http://purl.uniprot.org/uniprot/E1R9C9 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS02810 ^@ http://purl.uniprot.org/uniprot/E1RBG8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS06840 ^@ http://purl.uniprot.org/uniprot/E1R459 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS13065 ^@ http://purl.uniprot.org/uniprot/E1R4F6 ^@ Subcellular Location Annotation ^@ Periplasmic flagellum http://togogenome.org/gene/573413:SPIRS_RS11825 ^@ http://purl.uniprot.org/uniprot/E1R1T3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS10225 ^@ http://purl.uniprot.org/uniprot/E1R1K4 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/573413:SPIRS_RS04910 ^@ http://purl.uniprot.org/uniprot/E1RCM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/573413:SPIRS_RS18830 ^@ http://purl.uniprot.org/uniprot/E1R7W5 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/573413:SPIRS_RS12185 ^@ http://purl.uniprot.org/uniprot/E1R395 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS02975 ^@ http://purl.uniprot.org/uniprot/E1RBK2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/573413:SPIRS_RS10510 ^@ http://purl.uniprot.org/uniprot/E1R315 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/573413:SPIRS_RS02970 ^@ http://purl.uniprot.org/uniprot/E1RBK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RlmKL family.|||Cytoplasm|||Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. http://togogenome.org/gene/573413:SPIRS_RS13475 ^@ http://purl.uniprot.org/uniprot/E1R8L8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS17680 ^@ http://purl.uniprot.org/uniprot/E1R787 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/573413:SPIRS_RS03965 ^@ http://purl.uniprot.org/uniprot/E1RC40 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/573413:SPIRS_RS07215 ^@ http://purl.uniprot.org/uniprot/E1R521 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS03775 ^@ http://purl.uniprot.org/uniprot/E1RC01 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS15465 ^@ http://purl.uniprot.org/uniprot/E1R4S6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS02590 ^@ http://purl.uniprot.org/uniprot/E1RBC6 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/573413:SPIRS_RS03510 ^@ http://purl.uniprot.org/uniprot/E1RBV1 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/573413:SPIRS_RS07850 ^@ http://purl.uniprot.org/uniprot/E1R5R3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell inner membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/573413:SPIRS_RS19975 ^@ http://purl.uniprot.org/uniprot/E1R980 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS05250 ^@ http://purl.uniprot.org/uniprot/E1RCU4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/573413:SPIRS_RS07760 ^@ http://purl.uniprot.org/uniprot/E1R5P5 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/573413:SPIRS_RS10380 ^@ http://purl.uniprot.org/uniprot/E1R2Z0 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/573413:SPIRS_RS15875 ^@ http://purl.uniprot.org/uniprot/E1R5B7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS20215 ^@ http://purl.uniprot.org/uniprot/E1R9C7 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/573413:SPIRS_RS07495 ^@ http://purl.uniprot.org/uniprot/E1R577 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS04220 ^@ http://purl.uniprot.org/uniprot/E1RC92 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/573413:SPIRS_RS06880 ^@ http://purl.uniprot.org/uniprot/E1R467 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/573413:SPIRS_RS17495 ^@ http://purl.uniprot.org/uniprot/E1R2J5 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/573413:SPIRS_RS11740 ^@ http://purl.uniprot.org/uniprot/E1R1R6 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/573413:SPIRS_RS17920 ^@ http://purl.uniprot.org/uniprot/E1R7D5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS12985 ^@ http://purl.uniprot.org/uniprot/E1R4D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS09595 ^@ http://purl.uniprot.org/uniprot/E1R6K4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/573413:SPIRS_RS09190 ^@ http://purl.uniprot.org/uniprot/E1R6C3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/573413:SPIRS_RS15520 ^@ http://purl.uniprot.org/uniprot/E1R4T6 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/573413:SPIRS_RS14845 ^@ http://purl.uniprot.org/uniprot/E1R3S1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the selenophosphate synthase 1 family. Class I subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Homodimer.|||Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/573413:SPIRS_RS20025 ^@ http://purl.uniprot.org/uniprot/E1R990 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS12195 ^@ http://purl.uniprot.org/uniprot/E1R397 ^@ Function ^@ Catalyzes the synthesis of GMP from XMP. http://togogenome.org/gene/573413:SPIRS_RS03845 ^@ http://purl.uniprot.org/uniprot/E1RC15 ^@ Function|||Similarity ^@ Belongs to the Thz kinase family.|||Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). http://togogenome.org/gene/573413:SPIRS_RS20045 ^@ http://purl.uniprot.org/uniprot/E1R994 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS20130 ^@ http://purl.uniprot.org/uniprot/E1R9B1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS17135 ^@ http://purl.uniprot.org/uniprot/E1R2C4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS13570 ^@ http://purl.uniprot.org/uniprot/E1R8N7 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/573413:SPIRS_RS13170 ^@ http://purl.uniprot.org/uniprot/E1R4H7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/573413:SPIRS_RS16350 ^@ http://purl.uniprot.org/uniprot/E1R5K8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS21455 ^@ http://purl.uniprot.org/uniprot/E1RA20 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/573413:SPIRS_RS16125 ^@ http://purl.uniprot.org/uniprot/E1R5G8 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/573413:SPIRS_RS11280 ^@ http://purl.uniprot.org/uniprot/E1R724 ^@ Caution|||Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/573413:SPIRS_RS09110 ^@ http://purl.uniprot.org/uniprot/E1R6A8 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/573413:SPIRS_RS18580 ^@ http://purl.uniprot.org/uniprot/E1R7R5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/573413:SPIRS_RS13895 ^@ http://purl.uniprot.org/uniprot/E1R8V0 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/573413:SPIRS_RS02145 ^@ http://purl.uniprot.org/uniprot/E1RB43 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/573413:SPIRS_RS11510 ^@ http://purl.uniprot.org/uniprot/E1R771 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS19525 ^@ http://purl.uniprot.org/uniprot/E1R8Z0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS04940 ^@ http://purl.uniprot.org/uniprot/E1RCN2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/573413:SPIRS_RS17725 ^@ http://purl.uniprot.org/uniprot/E1R796 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS15705 ^@ http://purl.uniprot.org/uniprot/E1R4X3 ^@ Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family. http://togogenome.org/gene/573413:SPIRS_RS00160 ^@ http://purl.uniprot.org/uniprot/E1R6R1 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/573413:SPIRS_RS20835 ^@ http://purl.uniprot.org/uniprot/E1R9Q0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family.|||Homotrimer.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/573413:SPIRS_RS03650 ^@ http://purl.uniprot.org/uniprot/E1RBX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS21980 ^@ http://purl.uniprot.org/uniprot/E1R1F8 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/573413:SPIRS_RS06945 ^@ http://purl.uniprot.org/uniprot/E1R480 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS15185 ^@ http://purl.uniprot.org/uniprot/E1R3Y8 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/573413:SPIRS_RS19970 ^@ http://purl.uniprot.org/uniprot/E1R979 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS07975 ^@ http://purl.uniprot.org/uniprot/E1R5T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliN/MopA/SpaO family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS17610 ^@ http://purl.uniprot.org/uniprot/E1R2L8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/573413:SPIRS_RS05540 ^@ http://purl.uniprot.org/uniprot/E1R0Y2 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/573413:SPIRS_RS19710 ^@ http://purl.uniprot.org/uniprot/E1R927 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/573413:SPIRS_RS19070 ^@ http://purl.uniprot.org/uniprot/E1R813 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS09600 ^@ http://purl.uniprot.org/uniprot/E1R6K5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/573413:SPIRS_RS14465 ^@ http://purl.uniprot.org/uniprot/E1R282 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/573413:SPIRS_RS03715 ^@ http://purl.uniprot.org/uniprot/E1RBY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS21000 ^@ http://purl.uniprot.org/uniprot/E1R9T3 ^@ Similarity ^@ Belongs to the acetaldehyde dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS13060 ^@ http://purl.uniprot.org/uniprot/E1R4F5 ^@ Subcellular Location Annotation ^@ Periplasmic flagellum http://togogenome.org/gene/573413:SPIRS_RS20210 ^@ http://purl.uniprot.org/uniprot/E1R9C6 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/573413:SPIRS_RS02985 ^@ http://purl.uniprot.org/uniprot/E1RBK4 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS20245 ^@ http://purl.uniprot.org/uniprot/E1R9D3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS14470 ^@ http://purl.uniprot.org/uniprot/E1R283 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS09120 ^@ http://purl.uniprot.org/uniprot/E1R6B0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/573413:SPIRS_RS14950 ^@ http://purl.uniprot.org/uniprot/E1R3U1 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/573413:SPIRS_RS04095 ^@ http://purl.uniprot.org/uniprot/E1RC66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS07860 ^@ http://purl.uniprot.org/uniprot/E1R5R5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/573413:SPIRS_RS14490 ^@ http://purl.uniprot.org/uniprot/E1R287 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS15910 ^@ http://purl.uniprot.org/uniprot/E1R5C3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS07475 ^@ http://purl.uniprot.org/uniprot/E1R573 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS14945 ^@ http://purl.uniprot.org/uniprot/E1R3U0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS13115 ^@ http://purl.uniprot.org/uniprot/E1R4G6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial flagellin family.|||Component of the core of the flagella.|||Periplasm|||Periplasmic flagellum http://togogenome.org/gene/573413:SPIRS_RS16150 ^@ http://purl.uniprot.org/uniprot/E1R5H3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS13225 ^@ http://purl.uniprot.org/uniprot/E1R4I8 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/573413:SPIRS_RS15975 ^@ http://purl.uniprot.org/uniprot/E1R5D7 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/573413:SPIRS_RS04870 ^@ http://purl.uniprot.org/uniprot/E1RCL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/573413:SPIRS_RS11720 ^@ http://purl.uniprot.org/uniprot/E1R1R2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS18250 ^@ http://purl.uniprot.org/uniprot/E1R7J9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS00010 ^@ http://purl.uniprot.org/uniprot/E1R6N1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/573413:SPIRS_RS05225 ^@ http://purl.uniprot.org/uniprot/E1RCT9 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/573413:SPIRS_RS01440 ^@ http://purl.uniprot.org/uniprot/E1RAF0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/573413:SPIRS_RS17550 ^@ http://purl.uniprot.org/uniprot/E1R2K6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS00180 ^@ http://purl.uniprot.org/uniprot/E1R6R5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/573413:SPIRS_RS16675 ^@ http://purl.uniprot.org/uniprot/E1RAN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS12400 ^@ http://purl.uniprot.org/uniprot/E1R3D8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS18175 ^@ http://purl.uniprot.org/uniprot/E1R7I5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS12150 ^@ http://purl.uniprot.org/uniprot/E1R1Z3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS18545 ^@ http://purl.uniprot.org/uniprot/E1R7Q7 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/573413:SPIRS_RS06255 ^@ http://purl.uniprot.org/uniprot/E1R2T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS11355 ^@ http://purl.uniprot.org/uniprot/E1R740 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/573413:SPIRS_RS06855 ^@ http://purl.uniprot.org/uniprot/E1R462 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS20695 ^@ http://purl.uniprot.org/uniprot/E1R9M3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS19550 ^@ http://purl.uniprot.org/uniprot/E1R8Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the encapsulin family. Family 1 subfamily.|||Encapsulin nanocompartment http://togogenome.org/gene/573413:SPIRS_RS02770 ^@ http://purl.uniprot.org/uniprot/E1RBG0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/573413:SPIRS_RS04580 ^@ http://purl.uniprot.org/uniprot/E1RCG0 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/573413:SPIRS_RS04800 ^@ http://purl.uniprot.org/uniprot/E1RCK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/573413:SPIRS_RS00005 ^@ http://purl.uniprot.org/uniprot/E1R6M9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/573413:SPIRS_RS19760 ^@ http://purl.uniprot.org/uniprot/E1R937 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS14780 ^@ http://purl.uniprot.org/uniprot/E1R3Q8 ^@ Subcellular Location Annotation ^@ Periplasmic flagellum http://togogenome.org/gene/573413:SPIRS_RS03375 ^@ http://purl.uniprot.org/uniprot/E1RBS6 ^@ Similarity ^@ Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family. http://togogenome.org/gene/573413:SPIRS_RS02825 ^@ http://purl.uniprot.org/uniprot/E1RBH1 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/573413:SPIRS_RS01790 ^@ http://purl.uniprot.org/uniprot/E1RAY0 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/573413:SPIRS_RS04640 ^@ http://purl.uniprot.org/uniprot/E1RCH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS11370 ^@ http://purl.uniprot.org/uniprot/E1R743 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/573413:SPIRS_RS18095 ^@ http://purl.uniprot.org/uniprot/E1R7G9 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/573413:SPIRS_RS01070 ^@ http://purl.uniprot.org/uniprot/E1RA77 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/573413:SPIRS_RS04950 ^@ http://purl.uniprot.org/uniprot/E1RCN4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/573413:SPIRS_RS00120 ^@ http://purl.uniprot.org/uniprot/E1R6Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS06670 ^@ http://purl.uniprot.org/uniprot/E1R425 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/573413:SPIRS_RS05370 ^@ http://purl.uniprot.org/uniprot/E1R0U9 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/573413:SPIRS_RS07185 ^@ http://purl.uniprot.org/uniprot/E1R515 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/573413:SPIRS_RS14165 ^@ http://purl.uniprot.org/uniprot/E1R221 ^@ Subcellular Location Annotation ^@ Virion http://togogenome.org/gene/573413:SPIRS_RS18190 ^@ http://purl.uniprot.org/uniprot/E1R7I8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS11985 ^@ http://purl.uniprot.org/uniprot/E1R1W4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS17005 ^@ http://purl.uniprot.org/uniprot/E1RAU3 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/573413:SPIRS_RS11330 ^@ http://purl.uniprot.org/uniprot/E1R735 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/573413:SPIRS_RS19410 ^@ http://purl.uniprot.org/uniprot/E1R882 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS14585 ^@ http://purl.uniprot.org/uniprot/E1R3M0 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/573413:SPIRS_RS16660 ^@ http://purl.uniprot.org/uniprot/E1RAM8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS16395 ^@ http://purl.uniprot.org/uniprot/E1R5L7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS19660 ^@ http://purl.uniprot.org/uniprot/E1R917 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS09610 ^@ http://purl.uniprot.org/uniprot/E1R6K7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS00605 ^@ http://purl.uniprot.org/uniprot/E1R8D2 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/573413:SPIRS_RS04540 ^@ http://purl.uniprot.org/uniprot/E1RCF2 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/573413:SPIRS_RS16005 ^@ http://purl.uniprot.org/uniprot/E1R5E4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/573413:SPIRS_RS20315 ^@ http://purl.uniprot.org/uniprot/E1R9E7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS02805 ^@ http://purl.uniprot.org/uniprot/E1RBG7 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/573413:SPIRS_RS20330 ^@ http://purl.uniprot.org/uniprot/E1R9F0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/573413:SPIRS_RS18925 ^@ http://purl.uniprot.org/uniprot/E1R7Y4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/573413:SPIRS_RS02990 ^@ http://purl.uniprot.org/uniprot/E1RBK5 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/573413:SPIRS_RS00240 ^@ http://purl.uniprot.org/uniprot/E1R6S7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS05715 ^@ http://purl.uniprot.org/uniprot/E1R116 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/573413:SPIRS_RS07365 ^@ http://purl.uniprot.org/uniprot/E1R551 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/573413:SPIRS_RS01290 ^@ http://purl.uniprot.org/uniprot/E1RAC0 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/573413:SPIRS_RS02930 ^@ http://purl.uniprot.org/uniprot/E1RBJ2 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/573413:SPIRS_RS04185 ^@ http://purl.uniprot.org/uniprot/E1RC85 ^@ Caution|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS14645 ^@ http://purl.uniprot.org/uniprot/E1R3N2 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/573413:SPIRS_RS11745 ^@ http://purl.uniprot.org/uniprot/E1R1R7 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/573413:SPIRS_RS07955 ^@ http://purl.uniprot.org/uniprot/E1R5T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS06180 ^@ http://purl.uniprot.org/uniprot/E1R2S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS19055 ^@ http://purl.uniprot.org/uniprot/E1R810 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. http://togogenome.org/gene/573413:SPIRS_RS15240 ^@ http://purl.uniprot.org/uniprot/E1R4N2 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M38 family.|||Binds 2 Zn(2+) ions per subunit.|||Carbamylation allows a single lysine to coordinate two zinc ions.|||Carboxylation allows a single lysine to coordinate two zinc ions.|||Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS18850 ^@ http://purl.uniprot.org/uniprot/E1R7W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Nucleus http://togogenome.org/gene/573413:SPIRS_RS09685 ^@ http://purl.uniprot.org/uniprot/E1R6M2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/573413:SPIRS_RS20715 ^@ http://purl.uniprot.org/uniprot/E1R9M6 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/573413:SPIRS_RS07985 ^@ http://purl.uniprot.org/uniprot/E1R5U0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/573413:SPIRS_RS15085 ^@ http://purl.uniprot.org/uniprot/E1R3W8 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/573413:SPIRS_RS14820 ^@ http://purl.uniprot.org/uniprot/E1R3R6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS01455 ^@ http://purl.uniprot.org/uniprot/E1RAF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS13625 ^@ http://purl.uniprot.org/uniprot/E1R8P8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS17255 ^@ http://purl.uniprot.org/uniprot/E1R2E8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS04525 ^@ http://purl.uniprot.org/uniprot/E1RCE9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/573413:SPIRS_RS10285 ^@ http://purl.uniprot.org/uniprot/E1R1L6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS04230 ^@ http://purl.uniprot.org/uniprot/E1RC94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS02885 ^@ http://purl.uniprot.org/uniprot/E1RBI3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS04775 ^@ http://purl.uniprot.org/uniprot/E1RCJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/573413:SPIRS_RS13750 ^@ http://purl.uniprot.org/uniprot/E1R8S3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS20570 ^@ http://purl.uniprot.org/uniprot/E1R9J7 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/573413:SPIRS_RS14515 ^@ http://purl.uniprot.org/uniprot/E1R292 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/573413:SPIRS_RS01740 ^@ http://purl.uniprot.org/uniprot/E1RAX0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS16120 ^@ http://purl.uniprot.org/uniprot/E1R5G7 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/573413:SPIRS_RS03830 ^@ http://purl.uniprot.org/uniprot/E1RC12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS03210 ^@ http://purl.uniprot.org/uniprot/E1RBP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS15990 ^@ http://purl.uniprot.org/uniprot/E1R5E0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/573413:SPIRS_RS09040 ^@ http://purl.uniprot.org/uniprot/E1R194 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/573413:SPIRS_RS04605 ^@ http://purl.uniprot.org/uniprot/E1RCG5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily. http://togogenome.org/gene/573413:SPIRS_RS07305 ^@ http://purl.uniprot.org/uniprot/E1R539 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS19440 ^@ http://purl.uniprot.org/uniprot/E1R888 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/573413:SPIRS_RS09675 ^@ http://purl.uniprot.org/uniprot/E1R6M0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/573413:SPIRS_RS15950 ^@ http://purl.uniprot.org/uniprot/E1R5D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS15680 ^@ http://purl.uniprot.org/uniprot/E1R4W8 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/573413:SPIRS_RS11785 ^@ http://purl.uniprot.org/uniprot/E1R1S5 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/573413:SPIRS_RS13810 ^@ http://purl.uniprot.org/uniprot/E1R8T3 ^@ Similarity ^@ Belongs to the dihydropyrimidine dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS21560 ^@ http://purl.uniprot.org/uniprot/E1RA40 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS21620 ^@ http://purl.uniprot.org/uniprot/E1RA52 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/573413:SPIRS_RS08365 ^@ http://purl.uniprot.org/uniprot/E1R617 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/573413:SPIRS_RS18100 ^@ http://purl.uniprot.org/uniprot/E1R7H0 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/573413:SPIRS_RS08700 ^@ http://purl.uniprot.org/uniprot/E1R683 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/573413:SPIRS_RS08385 ^@ http://purl.uniprot.org/uniprot/E1R620 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS01210 ^@ http://purl.uniprot.org/uniprot/E1RAA5 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/573413:SPIRS_RS17755 ^@ http://purl.uniprot.org/uniprot/E1R7A2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS17580 ^@ http://purl.uniprot.org/uniprot/E1R2L2 ^@ Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS16385 ^@ http://purl.uniprot.org/uniprot/E1R5L5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS18055 ^@ http://purl.uniprot.org/uniprot/E1R7G1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS01820 ^@ http://purl.uniprot.org/uniprot/E1RAY6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS05430 ^@ http://purl.uniprot.org/uniprot/E1R0W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS17750 ^@ http://purl.uniprot.org/uniprot/E1R7A1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS10445 ^@ http://purl.uniprot.org/uniprot/E1R303 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS06240 ^@ http://purl.uniprot.org/uniprot/E1R2T5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm|||The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/573413:SPIRS_RS13345 ^@ http://purl.uniprot.org/uniprot/E1R4L0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/573413:SPIRS_RS05260 ^@ http://purl.uniprot.org/uniprot/E1RCU6 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/573413:SPIRS_RS04885 ^@ http://purl.uniprot.org/uniprot/E1RCL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/573413:SPIRS_RS18690 ^@ http://purl.uniprot.org/uniprot/E1R7T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS03175 ^@ http://purl.uniprot.org/uniprot/E1RBN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS02610 ^@ http://purl.uniprot.org/uniprot/E1RBD0 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/573413:SPIRS_RS11570 ^@ http://purl.uniprot.org/uniprot/E1R1N4 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/573413:SPIRS_RS05760 ^@ http://purl.uniprot.org/uniprot/E1R125 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/573413:SPIRS_RS13385 ^@ http://purl.uniprot.org/uniprot/E1R4L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS21520 ^@ http://purl.uniprot.org/uniprot/E1RA32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS16360 ^@ http://purl.uniprot.org/uniprot/E1R5L0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/573413:SPIRS_RS11495 ^@ http://purl.uniprot.org/uniprot/E1R768 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 2 subfamily.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS00460 ^@ http://purl.uniprot.org/uniprot/E1R8A5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/573413:SPIRS_RS06215 ^@ http://purl.uniprot.org/uniprot/E1R2T0 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/573413:SPIRS_RS04720 ^@ http://purl.uniprot.org/uniprot/E1RCI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS01630 ^@ http://purl.uniprot.org/uniprot/E1RAU9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/573413:SPIRS_RS03730 ^@ http://purl.uniprot.org/uniprot/E1RBZ2 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/573413:SPIRS_RS09670 ^@ http://purl.uniprot.org/uniprot/E1R6L9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/573413:SPIRS_RS17390 ^@ http://purl.uniprot.org/uniprot/E1R2H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS01575 ^@ http://purl.uniprot.org/uniprot/E1RAH7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS06525 ^@ http://purl.uniprot.org/uniprot/E1R401 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/573413:SPIRS_RS09575 ^@ http://purl.uniprot.org/uniprot/E1R6K0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS09475 ^@ http://purl.uniprot.org/uniprot/E1R6H9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/573413:SPIRS_RS09290 ^@ http://purl.uniprot.org/uniprot/E1R6E3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/573413:SPIRS_RS18225 ^@ http://purl.uniprot.org/uniprot/E1R7J5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS02725 ^@ http://purl.uniprot.org/uniprot/E1RBF3 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/573413:SPIRS_RS17635 ^@ http://purl.uniprot.org/uniprot/E1R778 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS01590 ^@ http://purl.uniprot.org/uniprot/E1RAI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS19305 ^@ http://purl.uniprot.org/uniprot/E1R861 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS10820 ^@ http://purl.uniprot.org/uniprot/E1R375 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/573413:SPIRS_RS07045 ^@ http://purl.uniprot.org/uniprot/E1R4A0 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/573413:SPIRS_RS21210 ^@ http://purl.uniprot.org/uniprot/E1R9X3 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/573413:SPIRS_RS17890 ^@ http://purl.uniprot.org/uniprot/E1R7C9 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/573413:SPIRS_RS09450 ^@ http://purl.uniprot.org/uniprot/E1R6H4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/573413:SPIRS_RS06160 ^@ http://purl.uniprot.org/uniprot/E1R2R9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/573413:SPIRS_RS14915 ^@ http://purl.uniprot.org/uniprot/E1R3T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS18940 ^@ http://purl.uniprot.org/uniprot/E1R7Y8 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/573413:SPIRS_RS15165 ^@ http://purl.uniprot.org/uniprot/E1R3Y4 ^@ Function|||Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family.|||This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). http://togogenome.org/gene/573413:SPIRS_RS16055 ^@ http://purl.uniprot.org/uniprot/E1R5F4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS12105 ^@ http://purl.uniprot.org/uniprot/E1R1Y4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS19855 ^@ http://purl.uniprot.org/uniprot/E1R956 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/573413:SPIRS_RS08860 ^@ http://purl.uniprot.org/uniprot/E1R159 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS14565 ^@ http://purl.uniprot.org/uniprot/E1R3L6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS16795 ^@ http://purl.uniprot.org/uniprot/E1RAQ5 ^@ Cofactor|||Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Binds 1 FAD per subunit.|||Binds 1 FMN covalently per subunit. http://togogenome.org/gene/573413:SPIRS_RS13965 ^@ http://purl.uniprot.org/uniprot/E1R8W3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS13785 ^@ http://purl.uniprot.org/uniprot/E1R8S8 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/573413:SPIRS_RS00430 ^@ http://purl.uniprot.org/uniprot/E1R8A4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/573413:SPIRS_RS15210 ^@ http://purl.uniprot.org/uniprot/E1R4M6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/573413:SPIRS_RS16475 ^@ http://purl.uniprot.org/uniprot/E1RAJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS12340 ^@ http://purl.uniprot.org/uniprot/E1R3C6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/573413:SPIRS_RS06810 ^@ http://purl.uniprot.org/uniprot/E1R453 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/573413:SPIRS_RS21200 ^@ http://purl.uniprot.org/uniprot/E1R9X1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/573413:SPIRS_RS01745 ^@ http://purl.uniprot.org/uniprot/E1RAX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS07520 ^@ http://purl.uniprot.org/uniprot/E1R582 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/573413:SPIRS_RS18530 ^@ http://purl.uniprot.org/uniprot/E1R7Q4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS07375 ^@ http://purl.uniprot.org/uniprot/E1R553 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.|||Homodimer.|||Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate. http://togogenome.org/gene/573413:SPIRS_RS04755 ^@ http://purl.uniprot.org/uniprot/E1RCJ5 ^@ Function|||Subunit ^@ Interacts with sigma-54.|||Required for activation of most nif operons, which are directly involved in nitrogen fixation. http://togogenome.org/gene/573413:SPIRS_RS09730 ^@ http://purl.uniprot.org/uniprot/E1R1A8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS03870 ^@ http://purl.uniprot.org/uniprot/E1RC20 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/573413:SPIRS_RS14020 ^@ http://purl.uniprot.org/uniprot/E1R8X4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/573413:SPIRS_RS14615 ^@ http://purl.uniprot.org/uniprot/E1R3M6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS00420 ^@ http://purl.uniprot.org/uniprot/E1R8A2 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/573413:SPIRS_RS08380 ^@ http://purl.uniprot.org/uniprot/E1R619 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS03985 ^@ http://purl.uniprot.org/uniprot/E1RC44 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS05025 ^@ http://purl.uniprot.org/uniprot/E1RCP9 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/573413:SPIRS_RS11160 ^@ http://purl.uniprot.org/uniprot/E1R700 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CitD family.|||Covalent carrier of the coenzyme of citrate lyase.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6. http://togogenome.org/gene/573413:SPIRS_RS11125 ^@ http://purl.uniprot.org/uniprot/E1R6Z2 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/573413:SPIRS_RS14675 ^@ http://purl.uniprot.org/uniprot/E1R3N8 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/573413:SPIRS_RS19340 ^@ http://purl.uniprot.org/uniprot/E1R868 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS12945 ^@ http://purl.uniprot.org/uniprot/E1R4D1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/573413:SPIRS_RS12990 ^@ http://purl.uniprot.org/uniprot/E1R4E0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS01865 ^@ http://purl.uniprot.org/uniprot/E1RAZ5 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/573413:SPIRS_RS19270 ^@ http://purl.uniprot.org/uniprot/E1R854 ^@ Similarity ^@ Belongs to the FtsK/SpoIIIE/SftA family. http://togogenome.org/gene/573413:SPIRS_RS01330 ^@ http://purl.uniprot.org/uniprot/E1RAC8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS09485 ^@ http://purl.uniprot.org/uniprot/E1R6I1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/573413:SPIRS_RS21760 ^@ http://purl.uniprot.org/uniprot/E1R1G9 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/573413:SPIRS_RS11155 ^@ http://purl.uniprot.org/uniprot/E1R6Z9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6.|||Represents a citryl-ACP lyase. http://togogenome.org/gene/573413:SPIRS_RS03060 ^@ http://purl.uniprot.org/uniprot/E1RBL8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the desulfoferrodoxin family.|||Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.|||Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.|||Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity. http://togogenome.org/gene/573413:SPIRS_RS08525 ^@ http://purl.uniprot.org/uniprot/E1R648 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/573413:SPIRS_RS18990 ^@ http://purl.uniprot.org/uniprot/E1R7Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS14600 ^@ http://purl.uniprot.org/uniprot/E1R3M3 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/573413:SPIRS_RS04860 ^@ http://purl.uniprot.org/uniprot/E1RCL4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/573413:SPIRS_RS07795 ^@ http://purl.uniprot.org/uniprot/E1R5Q2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/573413:SPIRS_RS19605 ^@ http://purl.uniprot.org/uniprot/E1R906 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS15290 ^@ http://purl.uniprot.org/uniprot/E1R4P2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS16925 ^@ http://purl.uniprot.org/uniprot/E1RAS9 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/573413:SPIRS_RS19755 ^@ http://purl.uniprot.org/uniprot/E1R936 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/573413:SPIRS_RS11435 ^@ http://purl.uniprot.org/uniprot/E1R756 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/573413:SPIRS_RS03460 ^@ http://purl.uniprot.org/uniprot/E1RBU2 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/573413:SPIRS_RS04065 ^@ http://purl.uniprot.org/uniprot/E1RC60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS04900 ^@ http://purl.uniprot.org/uniprot/E1RCM3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/573413:SPIRS_RS17710 ^@ http://purl.uniprot.org/uniprot/E1R793 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/573413:SPIRS_RS11360 ^@ http://purl.uniprot.org/uniprot/E1R741 ^@ Cofactor|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/573413:SPIRS_RS08320 ^@ http://purl.uniprot.org/uniprot/E1R608 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily.|||Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS19020 ^@ http://purl.uniprot.org/uniprot/E1R803 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/573413:SPIRS_RS00775 ^@ http://purl.uniprot.org/uniprot/E1R8G6 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/573413:SPIRS_RS09345 ^@ http://purl.uniprot.org/uniprot/E1R6F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS04415 ^@ http://purl.uniprot.org/uniprot/E1RCC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS17095 ^@ http://purl.uniprot.org/uniprot/E1R2B9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/573413:SPIRS_RS18120 ^@ http://purl.uniprot.org/uniprot/E1R7H4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS06470 ^@ http://purl.uniprot.org/uniprot/E1R3Z1 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/573413:SPIRS_RS05375 ^@ http://purl.uniprot.org/uniprot/E1R0V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS18945 ^@ http://purl.uniprot.org/uniprot/E1R7Y9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS05820 ^@ http://purl.uniprot.org/uniprot/E1R137 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS17545 ^@ http://purl.uniprot.org/uniprot/E1R2K5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS20770 ^@ http://purl.uniprot.org/uniprot/E1R9N7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS00690 ^@ http://purl.uniprot.org/uniprot/E1R8E9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS18585 ^@ http://purl.uniprot.org/uniprot/E1R7R6 ^@ Similarity ^@ Belongs to the glutaminase PdxT/SNO family. http://togogenome.org/gene/573413:SPIRS_RS06395 ^@ http://purl.uniprot.org/uniprot/E1R2W6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS10710 ^@ http://purl.uniprot.org/uniprot/E1R353 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS07200 ^@ http://purl.uniprot.org/uniprot/E1R518 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS11015 ^@ http://purl.uniprot.org/uniprot/E1R6X0 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/573413:SPIRS_RS04435 ^@ http://purl.uniprot.org/uniprot/E1RCD1 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/573413:SPIRS_RS19890 ^@ http://purl.uniprot.org/uniprot/E1R963 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS16780 ^@ http://purl.uniprot.org/uniprot/E1RAQ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS15400 ^@ http://purl.uniprot.org/uniprot/E1R4R4 ^@ Cofactor ^@ Binds 2 Mg(2+) ions per monomer. http://togogenome.org/gene/573413:SPIRS_RS09580 ^@ http://purl.uniprot.org/uniprot/E1R6K1 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/573413:SPIRS_RS21215 ^@ http://purl.uniprot.org/uniprot/E1R9X4 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/573413:SPIRS_RS21230 ^@ http://purl.uniprot.org/uniprot/E1R9X7 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/573413:SPIRS_RS20260 ^@ http://purl.uniprot.org/uniprot/E1R9D6 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS09175 ^@ http://purl.uniprot.org/uniprot/E1R6C1 ^@ Function|||Similarity ^@ Belongs to the SpoVG family.|||Could be involved in septation. http://togogenome.org/gene/573413:SPIRS_RS17350 ^@ http://purl.uniprot.org/uniprot/E1R2G7 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/573413:SPIRS_RS00590 ^@ http://purl.uniprot.org/uniprot/E1R8C9 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/573413:SPIRS_RS00870 ^@ http://purl.uniprot.org/uniprot/E1R8I5 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/573413:SPIRS_RS01655 ^@ http://purl.uniprot.org/uniprot/E1RAV3 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/573413:SPIRS_RS14665 ^@ http://purl.uniprot.org/uniprot/E1R3N6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/573413:SPIRS_RS11190 ^@ http://purl.uniprot.org/uniprot/E1R706 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS11565 ^@ http://purl.uniprot.org/uniprot/E1R1N3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS00765 ^@ http://purl.uniprot.org/uniprot/E1R8G4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/573413:SPIRS_RS08565 ^@ http://purl.uniprot.org/uniprot/E1R656 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS06040 ^@ http://purl.uniprot.org/uniprot/E1R2P7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS09570 ^@ http://purl.uniprot.org/uniprot/E1R6J9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial flagellin family.|||Component of the core of the flagella.|||Periplasm|||Periplasmic flagellum http://togogenome.org/gene/573413:SPIRS_RS01255 ^@ http://purl.uniprot.org/uniprot/E1RAB3 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/573413:SPIRS_RS07830 ^@ http://purl.uniprot.org/uniprot/E1R5Q9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/573413:SPIRS_RS02170 ^@ http://purl.uniprot.org/uniprot/E1RB48 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/573413:SPIRS_RS05405 ^@ http://purl.uniprot.org/uniprot/E1R0V7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/573413:SPIRS_RS18600 ^@ http://purl.uniprot.org/uniprot/E1R7R9 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/573413:SPIRS_RS03370 ^@ http://purl.uniprot.org/uniprot/E1RBS5 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/573413:SPIRS_RS05950 ^@ http://purl.uniprot.org/uniprot/E1R2M9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS15370 ^@ http://purl.uniprot.org/uniprot/E1R4Q8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/573413:SPIRS_RS21490 ^@ http://purl.uniprot.org/uniprot/E1RA26 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/573413:SPIRS_RS14495 ^@ http://purl.uniprot.org/uniprot/E1R288 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS14595 ^@ http://purl.uniprot.org/uniprot/E1R3M2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS14850 ^@ http://purl.uniprot.org/uniprot/E1R3S2 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/573413:SPIRS_RS03215 ^@ http://purl.uniprot.org/uniprot/E1RBP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS00710 ^@ http://purl.uniprot.org/uniprot/E1R8F3 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/573413:SPIRS_RS03410 ^@ http://purl.uniprot.org/uniprot/E1RBT2 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS03890 ^@ http://purl.uniprot.org/uniprot/E1RC25 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/573413:SPIRS_RS00040 ^@ http://purl.uniprot.org/uniprot/E1R6N7 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpB RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpA.|||Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS20580 ^@ http://purl.uniprot.org/uniprot/E1R9J9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS11490 ^@ http://purl.uniprot.org/uniprot/E1R767 ^@ Similarity ^@ Belongs to the RNA polymerase subunit omega family. http://togogenome.org/gene/573413:SPIRS_RS13120 ^@ http://purl.uniprot.org/uniprot/E1R4G7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial flagellin family.|||Component of the core of the flagella.|||Periplasm|||Periplasmic flagellum http://togogenome.org/gene/573413:SPIRS_RS16525 ^@ http://purl.uniprot.org/uniprot/E1RAK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS00150 ^@ http://purl.uniprot.org/uniprot/E1R6Q9 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/573413:SPIRS_RS03760 ^@ http://purl.uniprot.org/uniprot/E1RBZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS00095 ^@ http://purl.uniprot.org/uniprot/E1R6P8 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/573413:SPIRS_RS08825 ^@ http://purl.uniprot.org/uniprot/E1R6A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS16740 ^@ http://purl.uniprot.org/uniprot/E1RAP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-ACP thioesterase family.|||chloroplast http://togogenome.org/gene/573413:SPIRS_RS09585 ^@ http://purl.uniprot.org/uniprot/E1R6K2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS05070 ^@ http://purl.uniprot.org/uniprot/E1RCQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS04845 ^@ http://purl.uniprot.org/uniprot/E1RCL1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/573413:SPIRS_RS09500 ^@ http://purl.uniprot.org/uniprot/E1R6I4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/573413:SPIRS_RS03935 ^@ http://purl.uniprot.org/uniprot/E1RC34 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS13410 ^@ http://purl.uniprot.org/uniprot/E1R4M1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 51 family. http://togogenome.org/gene/573413:SPIRS_RS12345 ^@ http://purl.uniprot.org/uniprot/E1R3C7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS11140 ^@ http://purl.uniprot.org/uniprot/E1R6Z6 ^@ Similarity ^@ Belongs to the CitG/MdcB family. http://togogenome.org/gene/573413:SPIRS_RS11135 ^@ http://purl.uniprot.org/uniprot/E1R6Z5 ^@ Function ^@ Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase. http://togogenome.org/gene/573413:SPIRS_RS20265 ^@ http://purl.uniprot.org/uniprot/E1R9D7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS20305 ^@ http://purl.uniprot.org/uniprot/E1R9E6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS09640 ^@ http://purl.uniprot.org/uniprot/E1R6L3 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/573413:SPIRS_RS01080 ^@ http://purl.uniprot.org/uniprot/E1RA79 ^@ Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. http://togogenome.org/gene/573413:SPIRS_RS08625 ^@ http://purl.uniprot.org/uniprot/E1R668 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS15850 ^@ http://purl.uniprot.org/uniprot/E1R5B2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS14475 ^@ http://purl.uniprot.org/uniprot/E1R284 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/573413:SPIRS_RS07060 ^@ http://purl.uniprot.org/uniprot/E1R4A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS05625 ^@ http://purl.uniprot.org/uniprot/E1R0Z9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system. http://togogenome.org/gene/573413:SPIRS_RS08540 ^@ http://purl.uniprot.org/uniprot/E1R651 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/573413:SPIRS_RS02165 ^@ http://purl.uniprot.org/uniprot/E1RB47 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS15920 ^@ http://purl.uniprot.org/uniprot/E1R5C5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS08085 ^@ http://purl.uniprot.org/uniprot/E1R5W0 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS12320 ^@ http://purl.uniprot.org/uniprot/E1R3C2 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/573413:SPIRS_RS16680 ^@ http://purl.uniprot.org/uniprot/E1RAN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS13805 ^@ http://purl.uniprot.org/uniprot/E1R8T2 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/573413:SPIRS_RS17330 ^@ http://purl.uniprot.org/uniprot/E1R2G3 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/573413:SPIRS_RS20815 ^@ http://purl.uniprot.org/uniprot/E1R9P6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/573413:SPIRS_RS02400 ^@ http://purl.uniprot.org/uniprot/E1RB90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS21315 ^@ http://purl.uniprot.org/uniprot/E1R9Z2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS20995 ^@ http://purl.uniprot.org/uniprot/E1R9T2 ^@ Caution|||Similarity ^@ Belongs to the 4-hydroxy-2-oxovalerate aldolase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS12830 ^@ http://purl.uniprot.org/uniprot/E1R4B1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS08280 ^@ http://purl.uniprot.org/uniprot/E1R600 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system. http://togogenome.org/gene/573413:SPIRS_RS21285 ^@ http://purl.uniprot.org/uniprot/E1R9Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS07290 ^@ http://purl.uniprot.org/uniprot/E1R536 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/573413:SPIRS_RS07765 ^@ http://purl.uniprot.org/uniprot/E1R5P6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS14480 ^@ http://purl.uniprot.org/uniprot/E1R285 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS20235 ^@ http://purl.uniprot.org/uniprot/E1R9D1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the OadG family.|||Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS04625 ^@ http://purl.uniprot.org/uniprot/E1RCG9 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/573413:SPIRS_RS00290 ^@ http://purl.uniprot.org/uniprot/E1R6T7 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/573413:SPIRS_RS10835 ^@ http://purl.uniprot.org/uniprot/E1R378 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/573413:SPIRS_RS21545 ^@ http://purl.uniprot.org/uniprot/E1RA37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS15395 ^@ http://purl.uniprot.org/uniprot/E1R4R3 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/573413:SPIRS_RS04515 ^@ http://purl.uniprot.org/uniprot/E1RCE7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/573413:SPIRS_RS03620 ^@ http://purl.uniprot.org/uniprot/E1RBX0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS15450 ^@ http://purl.uniprot.org/uniprot/E1R4S3 ^@ Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family. http://togogenome.org/gene/573413:SPIRS_RS08115 ^@ http://purl.uniprot.org/uniprot/E1R5W7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/573413:SPIRS_RS09765 ^@ http://purl.uniprot.org/uniprot/E1R1B5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/573413:SPIRS_RS09020 ^@ http://purl.uniprot.org/uniprot/E1R190 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS06060 ^@ http://purl.uniprot.org/uniprot/E1R2Q1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS05800 ^@ http://purl.uniprot.org/uniprot/E1R133 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. http://togogenome.org/gene/573413:SPIRS_RS21655 ^@ http://purl.uniprot.org/uniprot/E1RA59 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/573413:SPIRS_RS00175 ^@ http://purl.uniprot.org/uniprot/E1R6R4 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/573413:SPIRS_RS06155 ^@ http://purl.uniprot.org/uniprot/E1R2R8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/573413:SPIRS_RS06145 ^@ http://purl.uniprot.org/uniprot/E1R2R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS10195 ^@ http://purl.uniprot.org/uniprot/E1R1J8 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/573413:SPIRS_RS06425 ^@ http://purl.uniprot.org/uniprot/E1R2X2 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/573413:SPIRS_RS10725 ^@ http://purl.uniprot.org/uniprot/E1R356 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS19080 ^@ http://purl.uniprot.org/uniprot/E1R815 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS03090 ^@ http://purl.uniprot.org/uniprot/E1RBM2 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/573413:SPIRS_RS16340 ^@ http://purl.uniprot.org/uniprot/E1R5K6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell inner membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/573413:SPIRS_RS08675 ^@ http://purl.uniprot.org/uniprot/E1R678 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/573413:SPIRS_RS09555 ^@ http://purl.uniprot.org/uniprot/E1R6J6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS07925 ^@ http://purl.uniprot.org/uniprot/E1R5S8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS13150 ^@ http://purl.uniprot.org/uniprot/E1R4H3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS18555 ^@ http://purl.uniprot.org/uniprot/E1R7Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/573413:SPIRS_RS13000 ^@ http://purl.uniprot.org/uniprot/E1R4E3 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/573413:SPIRS_RS18460 ^@ http://purl.uniprot.org/uniprot/E1R7P0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS06200 ^@ http://purl.uniprot.org/uniprot/E1R2S7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/573413:SPIRS_RS07965 ^@ http://purl.uniprot.org/uniprot/E1R5T6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS10570 ^@ http://purl.uniprot.org/uniprot/E1R325 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS07190 ^@ http://purl.uniprot.org/uniprot/E1R516 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS08255 ^@ http://purl.uniprot.org/uniprot/E1R5Z5 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/573413:SPIRS_RS08905 ^@ http://purl.uniprot.org/uniprot/E1R168 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/573413:SPIRS_RS12475 ^@ http://purl.uniprot.org/uniprot/E1R3F3 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/573413:SPIRS_RS14660 ^@ http://purl.uniprot.org/uniprot/E1R3N5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS16180 ^@ http://purl.uniprot.org/uniprot/E1R5H9 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/573413:SPIRS_RS10790 ^@ http://purl.uniprot.org/uniprot/E1R369 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/573413:SPIRS_RS06435 ^@ http://purl.uniprot.org/uniprot/E1R2X4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS03380 ^@ http://purl.uniprot.org/uniprot/E1RBS7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS01620 ^@ http://purl.uniprot.org/uniprot/E1RAU7 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/573413:SPIRS_RS09490 ^@ http://purl.uniprot.org/uniprot/E1R6I2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/573413:SPIRS_RS17720 ^@ http://purl.uniprot.org/uniprot/E1R795 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS07770 ^@ http://purl.uniprot.org/uniprot/E1R5P7 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/573413:SPIRS_RS14270 ^@ http://purl.uniprot.org/uniprot/E1R243 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/573413:SPIRS_RS13230 ^@ http://purl.uniprot.org/uniprot/E1R4I9 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/573413:SPIRS_RS18665 ^@ http://purl.uniprot.org/uniprot/E1R7T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS19610 ^@ http://purl.uniprot.org/uniprot/E1R907 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS15525 ^@ http://purl.uniprot.org/uniprot/E1R4T7 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/573413:SPIRS_RS06490 ^@ http://purl.uniprot.org/uniprot/E1R3Z4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/573413:SPIRS_RS06900 ^@ http://purl.uniprot.org/uniprot/E1R471 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS08135 ^@ http://purl.uniprot.org/uniprot/E1R5X1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS19700 ^@ http://purl.uniprot.org/uniprot/E1R925 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/573413:SPIRS_RS11590 ^@ http://purl.uniprot.org/uniprot/E1R1N8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/573413:SPIRS_RS09740 ^@ http://purl.uniprot.org/uniprot/E1R1B0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS04880 ^@ http://purl.uniprot.org/uniprot/E1RCL8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/573413:SPIRS_RS14410 ^@ http://purl.uniprot.org/uniprot/E1R271 ^@ Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). http://togogenome.org/gene/573413:SPIRS_RS17625 ^@ http://purl.uniprot.org/uniprot/E1R776 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS16335 ^@ http://purl.uniprot.org/uniprot/E1R5K5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/573413:SPIRS_RS17560 ^@ http://purl.uniprot.org/uniprot/E1R2K8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS00940 ^@ http://purl.uniprot.org/uniprot/E1R8J8 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/573413:SPIRS_RS20230 ^@ http://purl.uniprot.org/uniprot/E1R9D0 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/573413:SPIRS_RS09285 ^@ http://purl.uniprot.org/uniprot/E1R6E2 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/573413:SPIRS_RS17915 ^@ http://purl.uniprot.org/uniprot/E1R7D4 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/573413:SPIRS_RS04725 ^@ http://purl.uniprot.org/uniprot/E1RCI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS03235 ^@ http://purl.uniprot.org/uniprot/E1RBQ0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/573413:SPIRS_RS18075 ^@ http://purl.uniprot.org/uniprot/E1R7G5 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/573413:SPIRS_RS02550 ^@ http://purl.uniprot.org/uniprot/E1RBC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS05385 ^@ http://purl.uniprot.org/uniprot/E1R0V3 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/573413:SPIRS_RS18985 ^@ http://purl.uniprot.org/uniprot/E1R7Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS16030 ^@ http://purl.uniprot.org/uniprot/E1R5E9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS13265 ^@ http://purl.uniprot.org/uniprot/E1R4J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS20730 ^@ http://purl.uniprot.org/uniprot/E1R9M9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS05720 ^@ http://purl.uniprot.org/uniprot/E1R117 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS10365 ^@ http://purl.uniprot.org/uniprot/E1R2Y7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS02715 ^@ http://purl.uniprot.org/uniprot/E1RBF1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.|||Belongs to the SrkA/RdoA protein kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS04875 ^@ http://purl.uniprot.org/uniprot/E1RCL7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/573413:SPIRS_RS21145 ^@ http://purl.uniprot.org/uniprot/E1R9W0 ^@ Similarity ^@ Belongs to the SIS family. PHI subfamily. http://togogenome.org/gene/573413:SPIRS_RS13715 ^@ http://purl.uniprot.org/uniprot/E1R8R6 ^@ Similarity ^@ Belongs to the UPF0597 family. http://togogenome.org/gene/573413:SPIRS_RS05135 ^@ http://purl.uniprot.org/uniprot/E1RCS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS05255 ^@ http://purl.uniprot.org/uniprot/E1RCU5 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/573413:SPIRS_RS08250 ^@ http://purl.uniprot.org/uniprot/E1R5Z4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell inner membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS00080 ^@ http://purl.uniprot.org/uniprot/E1R6P5 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/573413:SPIRS_RS11815 ^@ http://purl.uniprot.org/uniprot/E1R1T1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS10655 ^@ http://purl.uniprot.org/uniprot/E1R342 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/573413:SPIRS_RS20370 ^@ http://purl.uniprot.org/uniprot/E1R9F7 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS04855 ^@ http://purl.uniprot.org/uniprot/E1RCL3 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/573413:SPIRS_RS19295 ^@ http://purl.uniprot.org/uniprot/E1R859 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/573413:SPIRS_RS07995 ^@ http://purl.uniprot.org/uniprot/E1R5U2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/573413:SPIRS_RS07815 ^@ http://purl.uniprot.org/uniprot/E1R5Q6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/573413:SPIRS_RS04995 ^@ http://purl.uniprot.org/uniprot/E1RCP3 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/573413:SPIRS_RS06980 ^@ http://purl.uniprot.org/uniprot/E1R487 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/573413:SPIRS_RS07900 ^@ http://purl.uniprot.org/uniprot/E1R5S3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/573413:SPIRS_RS13720 ^@ http://purl.uniprot.org/uniprot/E1R8R7 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/573413:SPIRS_RS09495 ^@ http://purl.uniprot.org/uniprot/E1R6I3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/573413:SPIRS_RS00745 ^@ http://purl.uniprot.org/uniprot/E1R8G0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS01735 ^@ http://purl.uniprot.org/uniprot/E1RAW9 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/573413:SPIRS_RS16300 ^@ http://purl.uniprot.org/uniprot/E1R5J8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M32 family.|||Binds 1 zinc ion per subunit.|||Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. http://togogenome.org/gene/573413:SPIRS_RS17645 ^@ http://purl.uniprot.org/uniprot/E1R780 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS03805 ^@ http://purl.uniprot.org/uniprot/E1RC07 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS17960 ^@ http://purl.uniprot.org/uniprot/E1R7E3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS03070 ^@ http://purl.uniprot.org/uniprot/E1RBM0 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/573413:SPIRS_RS18025 ^@ http://purl.uniprot.org/uniprot/E1R7F5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/573413:SPIRS_RS08840 ^@ http://purl.uniprot.org/uniprot/E1R155 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS03580 ^@ http://purl.uniprot.org/uniprot/E1RBW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS10300 ^@ http://purl.uniprot.org/uniprot/E1R1L9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS16375 ^@ http://purl.uniprot.org/uniprot/E1R5L3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/573413:SPIRS_RS20985 ^@ http://purl.uniprot.org/uniprot/E1R9T0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS20425 ^@ http://purl.uniprot.org/uniprot/E1R9G8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/573413:SPIRS_RS02300 ^@ http://purl.uniprot.org/uniprot/E1RB70 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/573413:SPIRS_RS00300 ^@ http://purl.uniprot.org/uniprot/E1R6T9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/573413:SPIRS_RS20615 ^@ http://purl.uniprot.org/uniprot/E1R9K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS18410 ^@ http://purl.uniprot.org/uniprot/E1R7N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS08835 ^@ http://purl.uniprot.org/uniprot/E1R154 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS17685 ^@ http://purl.uniprot.org/uniprot/E1R788 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS13640 ^@ http://purl.uniprot.org/uniprot/E1R8Q1 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/573413:SPIRS_RS21745 ^@ http://purl.uniprot.org/uniprot/E1R403 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/573413:SPIRS_RS17075 ^@ http://purl.uniprot.org/uniprot/E1R2B5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/573413:SPIRS_RS12215 ^@ http://purl.uniprot.org/uniprot/E1R3A1 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/573413:SPIRS_RS02690 ^@ http://purl.uniprot.org/uniprot/E1RBE6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS11915 ^@ http://purl.uniprot.org/uniprot/E1R1V0 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/573413:SPIRS_RS14870 ^@ http://purl.uniprot.org/uniprot/E1R3S6 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/573413:SPIRS_RS19325 ^@ http://purl.uniprot.org/uniprot/E1R865 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS15695 ^@ http://purl.uniprot.org/uniprot/E1R4X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS14860 ^@ http://purl.uniprot.org/uniprot/E1R3S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS03850 ^@ http://purl.uniprot.org/uniprot/E1RC16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/573413:SPIRS_RS01875 ^@ http://purl.uniprot.org/uniprot/E1RAZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS05090 ^@ http://purl.uniprot.org/uniprot/E1RCR2 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/573413:SPIRS_RS07835 ^@ http://purl.uniprot.org/uniprot/E1R5R0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS04115 ^@ http://purl.uniprot.org/uniprot/E1RC70 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/573413:SPIRS_RS16710 ^@ http://purl.uniprot.org/uniprot/E1RAN8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/573413:SPIRS_RS10780 ^@ http://purl.uniprot.org/uniprot/E1R367 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/573413:SPIRS_RS00720 ^@ http://purl.uniprot.org/uniprot/E1R8F5 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/573413:SPIRS_RS15020 ^@ http://purl.uniprot.org/uniprot/E1R3V5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS01625 ^@ http://purl.uniprot.org/uniprot/E1RAU8 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/573413:SPIRS_RS16380 ^@ http://purl.uniprot.org/uniprot/E1R5L4 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS12915 ^@ http://purl.uniprot.org/uniprot/E1R4C5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS15580 ^@ http://purl.uniprot.org/uniprot/E1R4U9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/573413:SPIRS_RS11450 ^@ http://purl.uniprot.org/uniprot/E1R759 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/573413:SPIRS_RS04070 ^@ http://purl.uniprot.org/uniprot/E1RC61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS07235 ^@ http://purl.uniprot.org/uniprot/E1R526 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/573413:SPIRS_RS13850 ^@ http://purl.uniprot.org/uniprot/E1R8U1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/573413:SPIRS_RS19960 ^@ http://purl.uniprot.org/uniprot/E1R977 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS09140 ^@ http://purl.uniprot.org/uniprot/E1R6B4 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/573413:SPIRS_RS17780 ^@ http://purl.uniprot.org/uniprot/E1R7A7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS00895 ^@ http://purl.uniprot.org/uniprot/E1R8J0 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/573413:SPIRS_RS16185 ^@ http://purl.uniprot.org/uniprot/E1R5I0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/573413:SPIRS_RS04320 ^@ http://purl.uniprot.org/uniprot/E1RCB1 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/573413:SPIRS_RS04750 ^@ http://purl.uniprot.org/uniprot/E1RCJ4 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/573413:SPIRS_RS01660 ^@ http://purl.uniprot.org/uniprot/E1RAV4 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/573413:SPIRS_RS08080 ^@ http://purl.uniprot.org/uniprot/E1R5V9 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/573413:SPIRS_RS20020 ^@ http://purl.uniprot.org/uniprot/E1R989 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arginine deiminase family.|||Cytoplasm http://togogenome.org/gene/573413:SPIRS_RS07150 ^@ http://purl.uniprot.org/uniprot/E1R508 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS02450 ^@ http://purl.uniprot.org/uniprot/E1RBA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/573413:SPIRS_RS04055 ^@ http://purl.uniprot.org/uniprot/E1RC58 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/573413:SPIRS_RS06460 ^@ http://purl.uniprot.org/uniprot/E1R2X9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS15980 ^@ http://purl.uniprot.org/uniprot/E1R5D8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/573413:SPIRS_RS08305 ^@ http://purl.uniprot.org/uniprot/E1R605 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/573413:SPIRS_RS07320 ^@ http://purl.uniprot.org/uniprot/E1R542 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/573413:SPIRS_RS08350 ^@ http://purl.uniprot.org/uniprot/E1R614 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/573413:SPIRS_RS17250 ^@ http://purl.uniprot.org/uniprot/E1R2E7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS07175 ^@ http://purl.uniprot.org/uniprot/E1R513 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/573413:SPIRS_RS08810 ^@ http://purl.uniprot.org/uniprot/E1R6A4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS03750 ^@ http://purl.uniprot.org/uniprot/E1RBZ6 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/573413:SPIRS_RS08600 ^@ http://purl.uniprot.org/uniprot/E1R663 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/573413:SPIRS_RS06220 ^@ http://purl.uniprot.org/uniprot/E1R2T1 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/573413:SPIRS_RS07875 ^@ http://purl.uniprot.org/uniprot/E1R5R8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/573413:SPIRS_RS20875 ^@ http://purl.uniprot.org/uniprot/E1R9Q8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/573413:SPIRS_RS08150 ^@ http://purl.uniprot.org/uniprot/E1R5X4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS19485 ^@ http://purl.uniprot.org/uniprot/E1R8Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/573413:SPIRS_RS11335 ^@ http://purl.uniprot.org/uniprot/E1R736 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/573413:SPIRS_RS09750 ^@ http://purl.uniprot.org/uniprot/E1R1B2 ^@ Caution|||Similarity ^@ Belongs to the ATP:guanido phosphotransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.