http://togogenome.org/gene/5741:GL50803_0014259 ^@ http://purl.uniprot.org/uniprot/Q868I8 ^@ Similarity ^@ Belongs to the acetyltransferase family. GNA1 subfamily. http://togogenome.org/gene/5741:GL50803_00121045 ^@ http://purl.uniprot.org/uniprot/E2RTQ0 ^@ Similarity ^@ Belongs to the histone H2B family. http://togogenome.org/gene/5741:GL50803_0089347 ^@ http://purl.uniprot.org/uniprot/Q8MUU2 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/5741:GL50803_008035 ^@ http://purl.uniprot.org/uniprot/Q8ISM1 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/5741:GL50803_007309 ^@ http://purl.uniprot.org/uniprot/Q95WU8 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/5741:GL50803_0017563 ^@ http://purl.uniprot.org/uniprot/Q8IS82 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/5741:GL50803_00102515 ^@ http://purl.uniprot.org/uniprot/Q8MX71 ^@ Similarity ^@ Belongs to the RdRP family. http://togogenome.org/gene/5741:GL50803_0011649 ^@ http://purl.uniprot.org/uniprot/Q4VPP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the annexin family. Giardin subunit alpha subfamily.|||Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk (By similarity).|||cytoskeleton http://togogenome.org/gene/5741:GL50803_0014581 ^@ http://purl.uniprot.org/uniprot/Q9BKB8 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/5741:GL50803_009827 ^@ http://purl.uniprot.org/uniprot/Q8IFV3 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/5741:GL50803_006148 ^@ http://purl.uniprot.org/uniprot/Q95WU5 ^@ Developmental Stage|||Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S9C family.|||Expressed throughout the life cycle, but expression is slightly decreased during encystation.|||Expression increased in response to the protease inhibitor bestatin.|||May be involved in metabolism of dipeptides or may affect host defense mechanisms.|||Membrane http://togogenome.org/gene/5741:GL50803_0021942 ^@ http://purl.uniprot.org/uniprot/A0A0F6PNH3 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/5741:GL50803_00101906 ^@ http://purl.uniprot.org/uniprot/Q8T6L4 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/5741:GL50803_00113656 ^@ http://purl.uniprot.org/uniprot/Q962W3 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/5741:GL50803_0016069 ^@ http://purl.uniprot.org/uniprot/Q964G3 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/5741:GL50803_0010829 ^@ http://purl.uniprot.org/uniprot/O97440|||http://purl.uniprot.org/uniprot/Q549P6 ^@ Similarity|||Subunit ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.|||Homohexamer. http://togogenome.org/gene/5741:GL50803_0011218 ^@ http://purl.uniprot.org/uniprot/Q86MB5 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/5741:GL50803_006563 ^@ http://purl.uniprot.org/uniprot/Q86QI1 ^@ Similarity ^@ Belongs to the UPRTase family. http://togogenome.org/gene/5741:GL50803_00135231 ^@ http://purl.uniprot.org/uniprot/E2RU30 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/5741:GL50803_0014256 ^@ http://purl.uniprot.org/uniprot/E2RU15 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5741:GL50803_003281 ^@ http://purl.uniprot.org/uniprot/Q5XTS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone deacetylase family. HD Type 1 subfamily.|||Nucleus http://togogenome.org/gene/5741:GL50803_0014048 ^@ http://purl.uniprot.org/uniprot/Q06Z46 ^@ Similarity ^@ Belongs to the MAPRE family. http://togogenome.org/gene/5741:GL50803_0016086 ^@ http://purl.uniprot.org/uniprot/Q76KS5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/5741:GL50803_00112079 ^@ http://purl.uniprot.org/uniprot/Q9U014 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/5741:GL50803_004812 ^@ http://purl.uniprot.org/uniprot/A7U7Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF-assemblin family.|||cytoskeleton http://togogenome.org/gene/5741:GL50803_0011683 ^@ http://purl.uniprot.org/uniprot/Q4VPP7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the annexin family. Giardin subunit alpha subfamily.|||Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk (By similarity).|||cytoskeleton http://togogenome.org/gene/5741:GL50803_007797 ^@ http://purl.uniprot.org/uniprot/Q4VPQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the annexin family. Giardin subunit alpha subfamily.|||Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk (By similarity).|||cytoskeleton http://togogenome.org/gene/5741:GL50803_009368 ^@ http://purl.uniprot.org/uniprot/Q86QZ3 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/5741:GL50803_0091919 ^@ http://purl.uniprot.org/uniprot/Q9GU05 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/5741:GL50803_0016343 ^@ http://purl.uniprot.org/uniprot/Q08014 ^@ Domain|||Function|||Subcellular Location Annotation ^@ May have a role in immobilizing the microtubules between cell divisions.|||Shows an alpha-helical coiled coil structure (30 repeating heptads).|||cytoskeleton http://togogenome.org/gene/5741:GL50803_0033083 ^@ http://purl.uniprot.org/uniprot/Q6WDA1 ^@ Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family. http://togogenome.org/gene/5741:GL50803_001721 ^@ http://purl.uniprot.org/uniprot/Q86GG9 ^@ Similarity ^@ Belongs to the TBP family. http://togogenome.org/gene/5741:GL50803_003331 ^@ http://purl.uniprot.org/uniprot/Q9Y1U1 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family. http://togogenome.org/gene/5741:GL50803_0013452 ^@ http://purl.uniprot.org/uniprot/Q0GK31 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/5741:GL50803_00103437 ^@ http://purl.uniprot.org/uniprot/Q4VPP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the annexin family. Giardin subunit alpha subfamily.|||Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk (By similarity).|||cytoskeleton http://togogenome.org/gene/5741:GL50803_00113554 ^@ http://purl.uniprot.org/uniprot/A8W233 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/5741:GL50803_0011654 ^@ http://purl.uniprot.org/uniprot/P17063|||http://purl.uniprot.org/uniprot/Q4VPP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the annexin family. Giardin subunit alpha subfamily.|||Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk.|||cytoskeleton http://togogenome.org/gene/5741:GL50803_0014451 ^@ http://purl.uniprot.org/uniprot/Q962W2 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/5741:GL50803_004039 ^@ http://purl.uniprot.org/uniprot/Q86LL4 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/5741:GL50803_0015144 ^@ http://purl.uniprot.org/uniprot/Q8MUU6 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RPB8 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/5741:GL50803_00104173 ^@ http://purl.uniprot.org/uniprot/Q5KTW2 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/5741:GL50803_008917 ^@ http://purl.uniprot.org/uniprot/Q8T4M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes medium subunit family.|||Membrane http://togogenome.org/gene/5741:GL50803_0015339 ^@ http://purl.uniprot.org/uniprot/Q8MZS1 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/5741:GL50803_0015869 ^@ http://purl.uniprot.org/uniprot/P38543 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small GTPase superfamily. Ran family.|||Found in a nuclear export complex with RanGTP, exportin and pre-miRNA (By similarity).|||GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).|||Nucleus http://togogenome.org/gene/5741:GL50803_00114787 ^@ http://purl.uniprot.org/uniprot/Q8ITF7 ^@ Function|||Subcellular Location Annotation ^@ Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk.|||cytoskeleton http://togogenome.org/gene/5741:GL50803_00103891 ^@ http://purl.uniprot.org/uniprot/O46319 ^@ Similarity ^@ Belongs to the chaperonin (HSP60) family. http://togogenome.org/gene/5741:GL50803_0021750 ^@ http://purl.uniprot.org/uniprot/O62580 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/5741:GL50803_0011992 ^@ http://purl.uniprot.org/uniprot/Q9GU01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/5741:GL50803_0013346 ^@ http://purl.uniprot.org/uniprot/Q86C21 ^@ Similarity ^@ Belongs to the RecA family. DMC1 subfamily. http://togogenome.org/gene/5741:GL50803_0096994 ^@ http://purl.uniprot.org/uniprot/Q8T6U7 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/5741:GL50803_00103935 ^@ http://purl.uniprot.org/uniprot/Q6WD95 ^@ Similarity ^@ Belongs to the RAD52 family. http://togogenome.org/gene/5741:GL50803_0010311 ^@ http://purl.uniprot.org/uniprot/O76458 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/5741:GL50803_006226 ^@ http://purl.uniprot.org/uniprot/Q964G4 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/5741:GL50803_0017043 ^@ http://purl.uniprot.org/uniprot/Q27661 ^@ Similarity|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/5741:GL50803_005328 ^@ http://purl.uniprot.org/uniprot/Q8T4M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cell membrane|||coated pit http://togogenome.org/gene/5741:GL50803_006304 ^@ http://purl.uniprot.org/uniprot/Q9BKJ3 ^@ Similarity ^@ Belongs to the NARF family. http://togogenome.org/gene/5741:GL50803_0017395 ^@ http://purl.uniprot.org/uniprot/Q76KS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uL18 family.|||Cytoplasm http://togogenome.org/gene/5741:GL50803_002851 ^@ http://purl.uniprot.org/uniprot/Q5XTS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MYST (SAS/MOZ) family.|||Nucleus http://togogenome.org/gene/5741:GL50803_0040817 ^@ http://purl.uniprot.org/uniprot/P51775 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.|||Belongs to the actin family.|||cytoskeleton http://togogenome.org/gene/5741:GL50803_0016975 ^@ http://purl.uniprot.org/uniprot/Q86BT9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase family.|||Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.|||Homodimer. http://togogenome.org/gene/5741:GL50803_00103676 ^@ http://purl.uniprot.org/uniprot/Q9U014 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/5741:GL50803_006626 ^@ http://purl.uniprot.org/uniprot/Q6WDA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MND1 family.|||Nucleus|||Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. http://togogenome.org/gene/5741:GL50803_0089622 ^@ http://purl.uniprot.org/uniprot/Q8T4M6 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/5741:GL50803_00114119 ^@ http://purl.uniprot.org/uniprot/Q4VPN9 ^@ Function|||Subcellular Location Annotation ^@ Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk.|||cytoskeleton http://togogenome.org/gene/5741:GL50803_006744 ^@ http://purl.uniprot.org/uniprot/Q94836 ^@ Similarity ^@ Belongs to the centrin family. http://togogenome.org/gene/5741:GL50803_0010530 ^@ http://purl.uniprot.org/uniprot/O62579 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Vacuole membrane http://togogenome.org/gene/5741:GL50803_007272 ^@ http://purl.uniprot.org/uniprot/Q5MJ52 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5741:GL50803_0014551 ^@ http://purl.uniprot.org/uniprot/Q4VPP5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the annexin family. Giardin subunit alpha subfamily.|||Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk (By similarity).|||cytoskeleton http://togogenome.org/gene/5741:GL50803_0015228 ^@ http://purl.uniprot.org/uniprot/Q76KS2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS8 family. http://togogenome.org/gene/5741:GL50803_00112304 ^@ http://purl.uniprot.org/uniprot/V6TF72 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/5741:GL50803_0011214 ^@ http://purl.uniprot.org/uniprot/A8W2E5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/5741:GL50803_0017587 ^@ http://purl.uniprot.org/uniprot/Q27660 ^@ Function|||Similarity ^@ Belongs to the CTP synthase family.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. http://togogenome.org/gene/5741:GL50803_00135002 ^@ http://purl.uniprot.org/uniprot/E2RU60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5741:GL50803_0017263 ^@ http://purl.uniprot.org/uniprot/Q5XTS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MYST (SAS/MOZ) family.|||Nucleus http://togogenome.org/gene/5741:GL50803_008565 ^@ http://purl.uniprot.org/uniprot/Q86GS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/5741:GL50803_007878 ^@ http://purl.uniprot.org/uniprot/Q76KS3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS11 family. http://togogenome.org/gene/5741:GL50803_0027521 ^@ http://purl.uniprot.org/uniprot/E2RU15 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5741:GL50803_003869 ^@ http://purl.uniprot.org/uniprot/Q95WU7 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/5741:GL50803_006184 ^@ http://purl.uniprot.org/uniprot/Q86QZ8 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/5741:GL50803_00103373 ^@ http://purl.uniprot.org/uniprot/Q4VPP1 ^@ Function|||Subcellular Location Annotation ^@ Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk.|||cytoskeleton http://togogenome.org/gene/5741:GL50803_007796 ^@ http://purl.uniprot.org/uniprot/P19389|||http://purl.uniprot.org/uniprot/Q4VPQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the annexin family. Giardin subunit alpha subfamily.|||Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk.|||cytoskeleton http://togogenome.org/gene/5741:GL50803_0014497 ^@ http://purl.uniprot.org/uniprot/Q9N9W5 ^@ Similarity ^@ Belongs to the peptidase T1A family. http://togogenome.org/gene/5741:GL50803_0016076 ^@ http://purl.uniprot.org/uniprot/V6T8I9 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/5741:GL50803_0016223 ^@ http://purl.uniprot.org/uniprot/P25202 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition (By similarity).|||Nucleus http://togogenome.org/gene/5741:GL50803_008245 ^@ http://purl.uniprot.org/uniprot/Q9U028 ^@ Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. http://togogenome.org/gene/5741:GL50803_0017254 ^@ http://purl.uniprot.org/uniprot/Q964G2 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/5741:GL50803_0097219 ^@ http://purl.uniprot.org/uniprot/Q24957 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methyltransferase superfamily. Fibrillarin family.|||By homology to other fibrillarins, some or all of the N-terminal domain arginines are modified to asymmetric dimethylarginine (DMA).|||Component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. It is associated with the U3, U8 and U13 small nuclear RNAs.|||S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity).|||nucleolus http://togogenome.org/gene/5741:GL50803_0017448 ^@ http://purl.uniprot.org/uniprot/Q8MUV2 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/5741:GL50803_0017230 ^@ http://purl.uniprot.org/uniprot/P38413 ^@ Function|||Subcellular Location Annotation ^@ Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk.|||cytoskeleton http://togogenome.org/gene/5741:GL50803_003036 ^@ http://purl.uniprot.org/uniprot/Q8MUU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/5741:GL50803_007474 ^@ http://purl.uniprot.org/uniprot/Q8MUV1 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/5741:GL50803_0011118 ^@ http://purl.uniprot.org/uniprot/Q8WP40 ^@ Similarity ^@ Belongs to the enolase family. http://togogenome.org/gene/5741:GL50803_007799 ^@ http://purl.uniprot.org/uniprot/Q4VPQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the annexin family. Giardin subunit alpha subfamily.|||Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk (By similarity).|||cytoskeleton http://togogenome.org/gene/5741:GL50803_0095162 ^@ http://purl.uniprot.org/uniprot/A0A8G0BLB9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/5741:GL50803_009115 ^@ http://purl.uniprot.org/uniprot/Q968V7 ^@ Similarity ^@ Belongs to the GPI family. http://togogenome.org/gene/5741:GL50803_0017153 ^@ http://purl.uniprot.org/uniprot/Q4VPP2 ^@ Function|||Subcellular Location Annotation ^@ Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk.|||cytoskeleton http://togogenome.org/gene/5741:GL50803_0035428 ^@ http://purl.uniprot.org/uniprot/O77443 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/5741:GL50803_00121046 ^@ http://purl.uniprot.org/uniprot/E2RTQ0 ^@ Similarity ^@ Belongs to the histone H2B family. http://togogenome.org/gene/5741:GL50803_0091198 ^@ http://purl.uniprot.org/uniprot/Q8T4M8 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/5741:GL50803_0016945 ^@ http://purl.uniprot.org/uniprot/Q06Z47 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/5741:GL50803_00112312 ^@ http://purl.uniprot.org/uniprot/V6TF72 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/5741:GL50803_00135003 ^@ http://purl.uniprot.org/uniprot/E2RU60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5741:GL50803_0093938 ^@ http://purl.uniprot.org/uniprot/A0A0F6PNL6|||http://purl.uniprot.org/uniprot/P36186 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.|||Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. http://togogenome.org/gene/5741:GL50803_0015127 ^@ http://purl.uniprot.org/uniprot/Q86QZ5 ^@ Similarity ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.