http://togogenome.org/gene/583355:CAKA_RS06620 ^@ http://purl.uniprot.org/uniprot/D5EIW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS05530 ^@ http://purl.uniprot.org/uniprot/D5EHW6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/583355:CAKA_RS02450 ^@ http://purl.uniprot.org/uniprot/D5EN97 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/583355:CAKA_RS15210 ^@ http://purl.uniprot.org/uniprot/D5EI35 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/583355:CAKA_RS14670 ^@ http://purl.uniprot.org/uniprot/D5ERB8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/583355:CAKA_RS09105 ^@ http://purl.uniprot.org/uniprot/D5EKA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/583355:CAKA_RS11625 ^@ http://purl.uniprot.org/uniprot/D5EMW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/583355:CAKA_RS10460 ^@ http://purl.uniprot.org/uniprot/D5ELI9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/583355:CAKA_RS05070 ^@ http://purl.uniprot.org/uniprot/D5EHM5 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/583355:CAKA_RS07555 ^@ http://purl.uniprot.org/uniprot/D5EJE7 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/583355:CAKA_RS07840 ^@ http://purl.uniprot.org/uniprot/D5EJK4 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/583355:CAKA_RS00980 ^@ http://purl.uniprot.org/uniprot/D5ELQ9 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/583355:CAKA_RS13245 ^@ http://purl.uniprot.org/uniprot/D5EPU8 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/583355:CAKA_RS05675 ^@ http://purl.uniprot.org/uniprot/D5EIB8 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/583355:CAKA_RS07860 ^@ http://purl.uniprot.org/uniprot/D5EJK8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/583355:CAKA_RS07545 ^@ http://purl.uniprot.org/uniprot/D5EJE5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/583355:CAKA_RS13875 ^@ http://purl.uniprot.org/uniprot/D5EQI9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/583355:CAKA_RS09750 ^@ http://purl.uniprot.org/uniprot/D5EKS3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS12085 ^@ http://purl.uniprot.org/uniprot/D5ENH3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS07165 ^@ http://purl.uniprot.org/uniprot/D5EJ71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS02895 ^@ http://purl.uniprot.org/uniprot/D5ENW8 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS08355 ^@ http://purl.uniprot.org/uniprot/D5EJV6 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/583355:CAKA_RS16220 ^@ http://purl.uniprot.org/uniprot/D5EMU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS08465 ^@ http://purl.uniprot.org/uniprot/D5EJX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/583355:CAKA_RS13265 ^@ http://purl.uniprot.org/uniprot/D5EPV1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/583355:CAKA_RS11875 ^@ http://purl.uniprot.org/uniprot/D5END1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS07855 ^@ http://purl.uniprot.org/uniprot/D5EJK7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family. http://togogenome.org/gene/583355:CAKA_RS07145 ^@ http://purl.uniprot.org/uniprot/D5EJ67 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/583355:CAKA_RS14695 ^@ http://purl.uniprot.org/uniprot/D5ERC3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS05585 ^@ http://purl.uniprot.org/uniprot/D5EIA2 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/583355:CAKA_RS05940 ^@ http://purl.uniprot.org/uniprot/D5EIG9 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/583355:CAKA_RS10050 ^@ http://purl.uniprot.org/uniprot/D5ELA5 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/583355:CAKA_RS14650 ^@ http://purl.uniprot.org/uniprot/D5ERB4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS14875 ^@ http://purl.uniprot.org/uniprot/D5ERG1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/583355:CAKA_RS12285 ^@ http://purl.uniprot.org/uniprot/D5ENL2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/583355:CAKA_RS03245 ^@ http://purl.uniprot.org/uniprot/D5EPF9 ^@ Similarity ^@ Belongs to the AAE transporter (TC 2.A.81) family. http://togogenome.org/gene/583355:CAKA_RS13760 ^@ http://purl.uniprot.org/uniprot/D5EQG8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS10525 ^@ http://purl.uniprot.org/uniprot/D5ELK2 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/583355:CAKA_RS12835 ^@ http://purl.uniprot.org/uniprot/D5EP89 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/583355:CAKA_RS08045 ^@ http://purl.uniprot.org/uniprot/D5EJP5 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/583355:CAKA_RS02415 ^@ http://purl.uniprot.org/uniprot/D5EN90 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS11490 ^@ http://purl.uniprot.org/uniprot/D5EMU0 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/583355:CAKA_RS10340 ^@ http://purl.uniprot.org/uniprot/D5ELG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS10495 ^@ http://purl.uniprot.org/uniprot/D5ELJ6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS12555 ^@ http://purl.uniprot.org/uniprot/D5EP34 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/583355:CAKA_RS15115 ^@ http://purl.uniprot.org/uniprot/D5EI14 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS03670 ^@ http://purl.uniprot.org/uniprot/D5EPP2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/583355:CAKA_RS05775 ^@ http://purl.uniprot.org/uniprot/D5EID7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/583355:CAKA_RS07755 ^@ http://purl.uniprot.org/uniprot/D5EJI6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TER reductase family.|||Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).|||Monomer. http://togogenome.org/gene/583355:CAKA_RS12815 ^@ http://purl.uniprot.org/uniprot/D5EP85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS03250 ^@ http://purl.uniprot.org/uniprot/D5EPG0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/583355:CAKA_RS15945 ^@ http://purl.uniprot.org/uniprot/D5EIP1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS12830 ^@ http://purl.uniprot.org/uniprot/D5EP88 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/583355:CAKA_RS14890 ^@ http://purl.uniprot.org/uniprot/D5EHW8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.|||Cell inner membrane|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/583355:CAKA_RS07565 ^@ http://purl.uniprot.org/uniprot/D5EJE9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS13675 ^@ http://purl.uniprot.org/uniprot/D5EQF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS09780 ^@ http://purl.uniprot.org/uniprot/D5EKS9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS09255 ^@ http://purl.uniprot.org/uniprot/D5EKD3 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/583355:CAKA_RS01105 ^@ http://purl.uniprot.org/uniprot/D5ELT4 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/583355:CAKA_RS11955 ^@ http://purl.uniprot.org/uniprot/D5ENE7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS09600 ^@ http://purl.uniprot.org/uniprot/D5EKP3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS08130 ^@ http://purl.uniprot.org/uniprot/D5EJR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family.|||Cell outer membrane http://togogenome.org/gene/583355:CAKA_RS05540 ^@ http://purl.uniprot.org/uniprot/D5EI93 ^@ Function|||Similarity ^@ Belongs to the HMBS family.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. http://togogenome.org/gene/583355:CAKA_RS09130 ^@ http://purl.uniprot.org/uniprot/D5EKA8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell inner membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/583355:CAKA_RS12290 ^@ http://purl.uniprot.org/uniprot/D5ENL3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/583355:CAKA_RS06260 ^@ http://purl.uniprot.org/uniprot/D5EIP0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/583355:CAKA_RS09160 ^@ http://purl.uniprot.org/uniprot/D5EKB4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/583355:CAKA_RS07680 ^@ http://purl.uniprot.org/uniprot/D5EJH0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/583355:CAKA_RS13860 ^@ http://purl.uniprot.org/uniprot/D5EQI6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/583355:CAKA_RS12360 ^@ http://purl.uniprot.org/uniprot/D5ENM7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/583355:CAKA_RS02490 ^@ http://purl.uniprot.org/uniprot/D5ENA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS12165 ^@ http://purl.uniprot.org/uniprot/D5ENI9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL31 family. http://togogenome.org/gene/583355:CAKA_RS07850 ^@ http://purl.uniprot.org/uniprot/D5EJK6 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS05825 ^@ http://purl.uniprot.org/uniprot/D5EIE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS13795 ^@ http://purl.uniprot.org/uniprot/D5EQH3 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS01260 ^@ http://purl.uniprot.org/uniprot/D5ELW8 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/583355:CAKA_RS12770 ^@ http://purl.uniprot.org/uniprot/D5EP76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/583355:CAKA_RS01740 ^@ http://purl.uniprot.org/uniprot/D5EMI4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/583355:CAKA_RS03415 ^@ http://purl.uniprot.org/uniprot/D5EPJ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/583355:CAKA_RS05805 ^@ http://purl.uniprot.org/uniprot/D5EIE3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS10190 ^@ http://purl.uniprot.org/uniprot/D5ELD3 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/583355:CAKA_RS08675 ^@ http://purl.uniprot.org/uniprot/D5EK21 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/583355:CAKA_RS12230 ^@ http://purl.uniprot.org/uniprot/D5ENK1 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/583355:CAKA_RS06845 ^@ http://purl.uniprot.org/uniprot/D5EJ08 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS11720 ^@ http://purl.uniprot.org/uniprot/D5EMY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS10420 ^@ http://purl.uniprot.org/uniprot/D5ELI1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS12950 ^@ http://purl.uniprot.org/uniprot/D5EPB2 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/583355:CAKA_RS11080 ^@ http://purl.uniprot.org/uniprot/D5EM86 ^@ Function|||Similarity ^@ Belongs to the nucleoside phosphorylase PpnP family.|||Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. http://togogenome.org/gene/583355:CAKA_RS00885 ^@ http://purl.uniprot.org/uniprot/D5ELN9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS11985 ^@ http://purl.uniprot.org/uniprot/D5ENF3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/583355:CAKA_RS08470 ^@ http://purl.uniprot.org/uniprot/D5EJX9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/583355:CAKA_RS11165 ^@ http://purl.uniprot.org/uniprot/D5EMA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS03945 ^@ http://purl.uniprot.org/uniprot/D5EQ65 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.|||Cytoplasm|||Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity. http://togogenome.org/gene/583355:CAKA_RS03740 ^@ http://purl.uniprot.org/uniprot/D5EPQ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/583355:CAKA_RS07135 ^@ http://purl.uniprot.org/uniprot/D5EJ65 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/583355:CAKA_RS08050 ^@ http://purl.uniprot.org/uniprot/D5EJP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS06625 ^@ http://purl.uniprot.org/uniprot/D5EIW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS15090 ^@ http://purl.uniprot.org/uniprot/D5EI09 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/583355:CAKA_RS07255 ^@ http://purl.uniprot.org/uniprot/D5EJ89 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/583355:CAKA_RS01255 ^@ http://purl.uniprot.org/uniprot/D5ELW7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/583355:CAKA_RS08290 ^@ http://purl.uniprot.org/uniprot/D5EJU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/583355:CAKA_RS08210 ^@ http://purl.uniprot.org/uniprot/D5EJS7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS05290 ^@ http://purl.uniprot.org/uniprot/D5EHR9 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/583355:CAKA_RS13420 ^@ http://purl.uniprot.org/uniprot/D5EPY3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RNase HII family. RnhC subfamily.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/583355:CAKA_RS09115 ^@ http://purl.uniprot.org/uniprot/D5EKA5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Belongs to the SecD/SecF family. SecF subfamily.|||Cell inner membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/583355:CAKA_RS13745 ^@ http://purl.uniprot.org/uniprot/D5EQG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/583355:CAKA_RS11465 ^@ http://purl.uniprot.org/uniprot/D5EMT5 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/583355:CAKA_RS14795 ^@ http://purl.uniprot.org/uniprot/D5ERE5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS03930 ^@ http://purl.uniprot.org/uniprot/D5EQ62 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS08285 ^@ http://purl.uniprot.org/uniprot/D5EJU2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/583355:CAKA_RS00990 ^@ http://purl.uniprot.org/uniprot/D5ELR1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/583355:CAKA_RS12355 ^@ http://purl.uniprot.org/uniprot/D5ENM6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/583355:CAKA_RS01100 ^@ http://purl.uniprot.org/uniprot/D5ELT3 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS09585 ^@ http://purl.uniprot.org/uniprot/D5EKP0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS01640 ^@ http://purl.uniprot.org/uniprot/D5EMG3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/583355:CAKA_RS13235 ^@ http://purl.uniprot.org/uniprot/D5EPU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS10650 ^@ http://purl.uniprot.org/uniprot/D5EM03 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/583355:CAKA_RS01755 ^@ http://purl.uniprot.org/uniprot/D5EMI7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/583355:CAKA_RS09425 ^@ http://purl.uniprot.org/uniprot/D5EKK8 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/583355:CAKA_RS01665 ^@ http://purl.uniprot.org/uniprot/D5EMG8 ^@ Cofactor ^@ Binds 1 FAD per subunit.|||Binds 1 FMN per subunit. http://togogenome.org/gene/583355:CAKA_RS15255 ^@ http://purl.uniprot.org/uniprot/D5EI44 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS09110 ^@ http://purl.uniprot.org/uniprot/D5EKA4 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/583355:CAKA_RS07805 ^@ http://purl.uniprot.org/uniprot/D5EJJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/583355:CAKA_RS15280 ^@ http://purl.uniprot.org/uniprot/D5EI49 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell inner membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/583355:CAKA_RS05035 ^@ http://purl.uniprot.org/uniprot/D5EHL7 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/583355:CAKA_RS08220 ^@ http://purl.uniprot.org/uniprot/D5EJS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS12295 ^@ http://purl.uniprot.org/uniprot/D5ENL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell inner membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/583355:CAKA_RS08300 ^@ http://purl.uniprot.org/uniprot/D5EJU5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/583355:CAKA_RS07910 ^@ http://purl.uniprot.org/uniprot/D5EJL8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS10565 ^@ http://purl.uniprot.org/uniprot/D5ELL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS07155 ^@ http://purl.uniprot.org/uniprot/D5EJ69 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/583355:CAKA_RS00095 ^@ http://purl.uniprot.org/uniprot/D5EKG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS07170 ^@ http://purl.uniprot.org/uniprot/D5EJ72 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/583355:CAKA_RS08900 ^@ http://purl.uniprot.org/uniprot/D5EK66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/583355:CAKA_RS13920 ^@ http://purl.uniprot.org/uniprot/D5EQJ8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/583355:CAKA_RS12385 ^@ http://purl.uniprot.org/uniprot/D5ENN3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS10310 ^@ http://purl.uniprot.org/uniprot/D5ELF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/583355:CAKA_RS12445 ^@ http://purl.uniprot.org/uniprot/D5EP11 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/583355:CAKA_RS11570 ^@ http://purl.uniprot.org/uniprot/D5EMV7 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS06820 ^@ http://purl.uniprot.org/uniprot/D5EJ03 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS11965 ^@ http://purl.uniprot.org/uniprot/D5ENE9 ^@ Similarity ^@ Belongs to the SurE nucleotidase family. http://togogenome.org/gene/583355:CAKA_RS12350 ^@ http://purl.uniprot.org/uniprot/D5ENM5 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/583355:CAKA_RS04100 ^@ http://purl.uniprot.org/uniprot/D5EQ95 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/583355:CAKA_RS11540 ^@ http://purl.uniprot.org/uniprot/D5EMV0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS14495 ^@ http://purl.uniprot.org/uniprot/D5ER84 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS10575 ^@ http://purl.uniprot.org/uniprot/D5ELL2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the flotillin-like FloA family.|||Cell membrane|||Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.|||Homooligomerizes.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane raft http://togogenome.org/gene/583355:CAKA_RS06665 ^@ http://purl.uniprot.org/uniprot/D5EIX0 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/583355:CAKA_RS08305 ^@ http://purl.uniprot.org/uniprot/D5EJU6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/583355:CAKA_RS02180 ^@ http://purl.uniprot.org/uniprot/D5EN43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS05255 ^@ http://purl.uniprot.org/uniprot/D5EHR2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/583355:CAKA_RS13710 ^@ http://purl.uniprot.org/uniprot/D5EQF7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/583355:CAKA_RS05630 ^@ http://purl.uniprot.org/uniprot/D5EIA9 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/583355:CAKA_RS14645 ^@ http://purl.uniprot.org/uniprot/D5ERB3 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/583355:CAKA_RS13895 ^@ http://purl.uniprot.org/uniprot/D5EQJ3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/583355:CAKA_RS12945 ^@ http://purl.uniprot.org/uniprot/D5EPB1 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/583355:CAKA_RS11705 ^@ http://purl.uniprot.org/uniprot/D5EMY4 ^@ Cofactor|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/583355:CAKA_RS14855 ^@ http://purl.uniprot.org/uniprot/D5ERF7 ^@ Similarity ^@ Belongs to the MscS (TC 1.A.23) family. http://togogenome.org/gene/583355:CAKA_RS08340 ^@ http://purl.uniprot.org/uniprot/D5EJV3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/583355:CAKA_RS08150 ^@ http://purl.uniprot.org/uniprot/D5EJR6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS07595 ^@ http://purl.uniprot.org/uniprot/D5EJF5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/583355:CAKA_RS05205 ^@ http://purl.uniprot.org/uniprot/D5EHQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the porin LamB (TC 1.B.3) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS13665 ^@ http://purl.uniprot.org/uniprot/D5EQE8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/583355:CAKA_RS10215 ^@ http://purl.uniprot.org/uniprot/D5ELD8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/583355:CAKA_RS02920 ^@ http://purl.uniprot.org/uniprot/D5ENX3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/583355:CAKA_RS00310 ^@ http://purl.uniprot.org/uniprot/D5EKZ1 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.|||Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.|||Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Periplasm|||Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. http://togogenome.org/gene/583355:CAKA_RS06870 ^@ http://purl.uniprot.org/uniprot/D5EJ13 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/583355:CAKA_RS10020 ^@ http://purl.uniprot.org/uniprot/D5EL99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/583355:CAKA_RS04360 ^@ http://purl.uniprot.org/uniprot/D5EQS3 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/583355:CAKA_RS03845 ^@ http://purl.uniprot.org/uniprot/D5EQ45 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/583355:CAKA_RS03490 ^@ http://purl.uniprot.org/uniprot/D5EPK5 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/583355:CAKA_RS15235 ^@ http://purl.uniprot.org/uniprot/D5EI40 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/583355:CAKA_RS07100 ^@ http://purl.uniprot.org/uniprot/D5EJ59 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/583355:CAKA_RS03710 ^@ http://purl.uniprot.org/uniprot/D5EPQ2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS03875 ^@ http://purl.uniprot.org/uniprot/D5EQ51 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/583355:CAKA_RS02385 ^@ http://purl.uniprot.org/uniprot/D5EN84 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/583355:CAKA_RS05930 ^@ http://purl.uniprot.org/uniprot/D5EIG7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/583355:CAKA_RS14285 ^@ http://purl.uniprot.org/uniprot/D5EQS0 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/583355:CAKA_RS01005 ^@ http://purl.uniprot.org/uniprot/D5ELR4 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/583355:CAKA_RS07990 ^@ http://purl.uniprot.org/uniprot/D5EJN4 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/583355:CAKA_RS12145 ^@ http://purl.uniprot.org/uniprot/D5ENI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/583355:CAKA_RS07560 ^@ http://purl.uniprot.org/uniprot/D5EJE8 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/583355:CAKA_RS01050 ^@ http://purl.uniprot.org/uniprot/D5ELS3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/583355:CAKA_RS14950 ^@ http://purl.uniprot.org/uniprot/D5EHX9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/583355:CAKA_RS08225 ^@ http://purl.uniprot.org/uniprot/D5EJT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS04295 ^@ http://purl.uniprot.org/uniprot/D5EQD4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS11105 ^@ http://purl.uniprot.org/uniprot/D5EM91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS11195 ^@ http://purl.uniprot.org/uniprot/D5EMA8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/583355:CAKA_RS08625 ^@ http://purl.uniprot.org/uniprot/D5EK11 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS14565 ^@ http://purl.uniprot.org/uniprot/D5ER98 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/583355:CAKA_RS13955 ^@ http://purl.uniprot.org/uniprot/D5EQK5 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/583355:CAKA_RS06360 ^@ http://purl.uniprot.org/uniprot/D5EIR0 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/583355:CAKA_RS07605 ^@ http://purl.uniprot.org/uniprot/D5EJF7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS07300 ^@ http://purl.uniprot.org/uniprot/D5EJ98 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/583355:CAKA_RS07915 ^@ http://purl.uniprot.org/uniprot/D5EJL9 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/583355:CAKA_RS14680 ^@ http://purl.uniprot.org/uniprot/D5ERC0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/583355:CAKA_RS12735 ^@ http://purl.uniprot.org/uniprot/D5EP68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS04140 ^@ http://purl.uniprot.org/uniprot/D5EQA3 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/583355:CAKA_RS10380 ^@ http://purl.uniprot.org/uniprot/D5ELH3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS12025 ^@ http://purl.uniprot.org/uniprot/D5ENG1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS05790 ^@ http://purl.uniprot.org/uniprot/D5EIE0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/583355:CAKA_RS10320 ^@ http://purl.uniprot.org/uniprot/D5ELG0 ^@ Caution|||Function|||Similarity ^@ Belongs to the transcriptional regulatory CopG/NikR family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transcriptional regulator. http://togogenome.org/gene/583355:CAKA_RS10700 ^@ http://purl.uniprot.org/uniprot/D5EM14 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/583355:CAKA_RS14785 ^@ http://purl.uniprot.org/uniprot/D5ERE3 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/583355:CAKA_RS04505 ^@ http://purl.uniprot.org/uniprot/D5EQV6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/583355:CAKA_RS03880 ^@ http://purl.uniprot.org/uniprot/D5EQ52 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS13075 ^@ http://purl.uniprot.org/uniprot/D5EPR5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS06725 ^@ http://purl.uniprot.org/uniprot/D5EIY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS15230 ^@ http://purl.uniprot.org/uniprot/D5EI39 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS07570 ^@ http://purl.uniprot.org/uniprot/D5EJF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS15245 ^@ http://purl.uniprot.org/uniprot/D5EI42 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS03320 ^@ http://purl.uniprot.org/uniprot/D5EPH1 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/583355:CAKA_RS15675 ^@ http://purl.uniprot.org/uniprot/D5EMN1 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/583355:CAKA_RS06225 ^@ http://purl.uniprot.org/uniprot/D5EIN3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/583355:CAKA_RS01150 ^@ http://purl.uniprot.org/uniprot/D5ELU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS14005 ^@ http://purl.uniprot.org/uniprot/D5EQL6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/583355:CAKA_RS14945 ^@ http://purl.uniprot.org/uniprot/D5EHX8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/583355:CAKA_RS14815 ^@ http://purl.uniprot.org/uniprot/D5ERE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/583355:CAKA_RS16135 ^@ http://purl.uniprot.org/uniprot/D5ELD5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/583355:CAKA_RS08195 ^@ http://purl.uniprot.org/uniprot/D5EJS4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/583355:CAKA_RS03640 ^@ http://purl.uniprot.org/uniprot/D5EPN6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/583355:CAKA_RS05820 ^@ http://purl.uniprot.org/uniprot/D5EIE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/583355:CAKA_RS14265 ^@ http://purl.uniprot.org/uniprot/D5EQR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS05510 ^@ http://purl.uniprot.org/uniprot/D5EHW3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/583355:CAKA_RS12120 ^@ http://purl.uniprot.org/uniprot/D5ENI0 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/583355:CAKA_RS00210 ^@ http://purl.uniprot.org/uniprot/D5EKX0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS13510 ^@ http://purl.uniprot.org/uniprot/D5EQ00 ^@ Similarity ^@ Belongs to the UPF0502 family. http://togogenome.org/gene/583355:CAKA_RS12865 ^@ http://purl.uniprot.org/uniprot/D5EP95 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/583355:CAKA_RS10015 ^@ http://purl.uniprot.org/uniprot/D5EL98 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS06520 ^@ http://purl.uniprot.org/uniprot/D5EIU1 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/583355:CAKA_RS09810 ^@ http://purl.uniprot.org/uniprot/D5EKT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/583355:CAKA_RS08685 ^@ http://purl.uniprot.org/uniprot/D5EK23 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/583355:CAKA_RS02425 ^@ http://purl.uniprot.org/uniprot/D5EN92 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS10080 ^@ http://purl.uniprot.org/uniprot/D5ELB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS12795 ^@ http://purl.uniprot.org/uniprot/D5EP81 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell inner membrane|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/583355:CAKA_RS03185 ^@ http://purl.uniprot.org/uniprot/D5EPE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS10470 ^@ http://purl.uniprot.org/uniprot/D5ELJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/583355:CAKA_RS08295 ^@ http://purl.uniprot.org/uniprot/D5EJU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/583355:CAKA_RS07790 ^@ http://purl.uniprot.org/uniprot/D5EJJ4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS06950 ^@ http://purl.uniprot.org/uniprot/D5EJ29 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/583355:CAKA_RS12880 ^@ http://purl.uniprot.org/uniprot/D5EP98 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/583355:CAKA_RS09185 ^@ http://purl.uniprot.org/uniprot/D5EKB9 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/583355:CAKA_RS10120 ^@ http://purl.uniprot.org/uniprot/D5ELB9 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/583355:CAKA_RS02085 ^@ http://purl.uniprot.org/uniprot/D5EN23 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 16 family. http://togogenome.org/gene/583355:CAKA_RS10105 ^@ http://purl.uniprot.org/uniprot/D5ELB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS12010 ^@ http://purl.uniprot.org/uniprot/D5ENF8 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS10410 ^@ http://purl.uniprot.org/uniprot/D5ELH9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS05025 ^@ http://purl.uniprot.org/uniprot/D5EHL5 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/583355:CAKA_RS11110 ^@ http://purl.uniprot.org/uniprot/D5EM92 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/583355:CAKA_RS09320 ^@ http://purl.uniprot.org/uniprot/D5EKE6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/583355:CAKA_RS07000 ^@ http://purl.uniprot.org/uniprot/D5EJ39 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/583355:CAKA_RS10335 ^@ http://purl.uniprot.org/uniprot/D5ELG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/583355:CAKA_RS06285 ^@ http://purl.uniprot.org/uniprot/D5EIP5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/583355:CAKA_RS03495 ^@ http://purl.uniprot.org/uniprot/D5EPK6 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival. http://togogenome.org/gene/583355:CAKA_RS01845 ^@ http://purl.uniprot.org/uniprot/D5EMK5 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/583355:CAKA_RS05305 ^@ http://purl.uniprot.org/uniprot/D5EHS2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/583355:CAKA_RS11900 ^@ http://purl.uniprot.org/uniprot/D5END6 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/583355:CAKA_RS13765 ^@ http://purl.uniprot.org/uniprot/D5EQG9 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/583355:CAKA_RS00395 ^@ http://purl.uniprot.org/uniprot/D5EL08 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily. http://togogenome.org/gene/583355:CAKA_RS04665 ^@ http://purl.uniprot.org/uniprot/D5EQY9 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily. http://togogenome.org/gene/583355:CAKA_RS06280 ^@ http://purl.uniprot.org/uniprot/D5EIP4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/583355:CAKA_RS12475 ^@ http://purl.uniprot.org/uniprot/D5EP17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS08455 ^@ http://purl.uniprot.org/uniprot/D5EJX6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/583355:CAKA_RS13945 ^@ http://purl.uniprot.org/uniprot/D5EQK3 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/583355:CAKA_RS11350 ^@ http://purl.uniprot.org/uniprot/D5EMR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS14760 ^@ http://purl.uniprot.org/uniprot/D5ERD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS14690 ^@ http://purl.uniprot.org/uniprot/D5ERC2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS14715 ^@ http://purl.uniprot.org/uniprot/D5ERC8 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/583355:CAKA_RS07870 ^@ http://purl.uniprot.org/uniprot/D5EJL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS13005 ^@ http://purl.uniprot.org/uniprot/D5EPC3 ^@ Similarity ^@ Belongs to the OprB family. http://togogenome.org/gene/583355:CAKA_RS08910 ^@ http://purl.uniprot.org/uniprot/D5EK68 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/583355:CAKA_RS11550 ^@ http://purl.uniprot.org/uniprot/D5EMV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS15445 ^@ http://purl.uniprot.org/uniprot/D5EI87 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/583355:CAKA_RS00985 ^@ http://purl.uniprot.org/uniprot/D5ELR0 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/583355:CAKA_RS06480 ^@ http://purl.uniprot.org/uniprot/D5EIT3 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/583355:CAKA_RS03625 ^@ http://purl.uniprot.org/uniprot/D5EPN3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/583355:CAKA_RS03565 ^@ http://purl.uniprot.org/uniprot/D5EPM0 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/583355:CAKA_RS11980 ^@ http://purl.uniprot.org/uniprot/D5ENF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS08810 ^@ http://purl.uniprot.org/uniprot/D5EK48 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/583355:CAKA_RS11870 ^@ http://purl.uniprot.org/uniprot/D5END0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS03915 ^@ http://purl.uniprot.org/uniprot/D5EQ59 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/583355:CAKA_RS08375 ^@ http://purl.uniprot.org/uniprot/D5EJW0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/583355:CAKA_RS04740 ^@ http://purl.uniprot.org/uniprot/D5ER03 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/583355:CAKA_RS13580 ^@ http://purl.uniprot.org/uniprot/D5EQ14 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/583355:CAKA_RS05325 ^@ http://purl.uniprot.org/uniprot/D5EHS6 ^@ Similarity ^@ Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family. http://togogenome.org/gene/583355:CAKA_RS07150 ^@ http://purl.uniprot.org/uniprot/D5EJ68 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/583355:CAKA_RS03360 ^@ http://purl.uniprot.org/uniprot/D5EPH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS10040 ^@ http://purl.uniprot.org/uniprot/D5ELA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/583355:CAKA_RS09730 ^@ http://purl.uniprot.org/uniprot/D5EKR9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS03050 ^@ http://purl.uniprot.org/uniprot/D5ENZ9 ^@ Cofactor|||PTM|||Subcellular Location Annotation ^@ Binds 2 heme groups per subunit.|||Binds 2 heme groups.|||Periplasm http://togogenome.org/gene/583355:CAKA_RS07845 ^@ http://purl.uniprot.org/uniprot/D5EJK5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/583355:CAKA_RS01610 ^@ http://purl.uniprot.org/uniprot/D5EMF7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/583355:CAKA_RS02050 ^@ http://purl.uniprot.org/uniprot/D5EN16 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS07005 ^@ http://purl.uniprot.org/uniprot/D5EJ40 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/583355:CAKA_RS11100 ^@ http://purl.uniprot.org/uniprot/D5EM90 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/583355:CAKA_RS06835 ^@ http://purl.uniprot.org/uniprot/D5EJ06 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS09710 ^@ http://purl.uniprot.org/uniprot/D5EKR5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS14330 ^@ http://purl.uniprot.org/uniprot/D5ER51 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS13720 ^@ http://purl.uniprot.org/uniprot/D5EQG0 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/583355:CAKA_RS03695 ^@ http://purl.uniprot.org/uniprot/D5EPP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/583355:CAKA_RS09945 ^@ http://purl.uniprot.org/uniprot/D5EKW2 ^@ Similarity ^@ Belongs to the HisA/HisF family. http://togogenome.org/gene/583355:CAKA_RS00085 ^@ http://purl.uniprot.org/uniprot/D5EKG5 ^@ Cofactor ^@ Binds 4 heme c groups covalently per monomer. http://togogenome.org/gene/583355:CAKA_RS12800 ^@ http://purl.uniprot.org/uniprot/D5EP82 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/583355:CAKA_RS11095 ^@ http://purl.uniprot.org/uniprot/D5EM89 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/583355:CAKA_RS04240 ^@ http://purl.uniprot.org/uniprot/D5EQC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS09835 ^@ http://purl.uniprot.org/uniprot/D5EKT9 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/583355:CAKA_RS00680 ^@ http://purl.uniprot.org/uniprot/D5EL70 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS00040 ^@ http://purl.uniprot.org/uniprot/D5EKF6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS06055 ^@ http://purl.uniprot.org/uniprot/D5EIJ0 ^@ Similarity ^@ Belongs to the peptidase S24 family. http://togogenome.org/gene/583355:CAKA_RS14085 ^@ http://purl.uniprot.org/uniprot/D5EQN2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/583355:CAKA_RS04645 ^@ http://purl.uniprot.org/uniprot/D5EQY5 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily. http://togogenome.org/gene/583355:CAKA_RS02185 ^@ http://purl.uniprot.org/uniprot/D5EN44 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS08645 ^@ http://purl.uniprot.org/uniprot/D5EK15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS13600 ^@ http://purl.uniprot.org/uniprot/D5EQ18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS01815 ^@ http://purl.uniprot.org/uniprot/D5EMJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS10425 ^@ http://purl.uniprot.org/uniprot/D5ELI2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/583355:CAKA_RS14905 ^@ http://purl.uniprot.org/uniprot/D5EHX0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS09260 ^@ http://purl.uniprot.org/uniprot/D5EKD4 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/583355:CAKA_RS15130 ^@ http://purl.uniprot.org/uniprot/D5EI17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS02110 ^@ http://purl.uniprot.org/uniprot/D5EN28 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/583355:CAKA_RS01585 ^@ http://purl.uniprot.org/uniprot/D5EMF2 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/583355:CAKA_RS00465 ^@ http://purl.uniprot.org/uniprot/D5EL24 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/583355:CAKA_RS05335 ^@ http://purl.uniprot.org/uniprot/D5EHS8 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/583355:CAKA_RS14480 ^@ http://purl.uniprot.org/uniprot/D5ER81 ^@ Similarity ^@ Belongs to the cytochrome c-552 family. http://togogenome.org/gene/583355:CAKA_RS08275 ^@ http://purl.uniprot.org/uniprot/D5EJU0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/583355:CAKA_RS11830 ^@ http://purl.uniprot.org/uniprot/D5ENC2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/583355:CAKA_RS13425 ^@ http://purl.uniprot.org/uniprot/D5EPY4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RNase HII family.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/583355:CAKA_RS10980 ^@ http://purl.uniprot.org/uniprot/D5EM67 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/583355:CAKA_RS08590 ^@ http://purl.uniprot.org/uniprot/D5EK03 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/583355:CAKA_RS00305 ^@ http://purl.uniprot.org/uniprot/D5EKZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NapB family.|||Periplasm http://togogenome.org/gene/583355:CAKA_RS10790 ^@ http://purl.uniprot.org/uniprot/D5EM32 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/583355:CAKA_RS05320 ^@ http://purl.uniprot.org/uniprot/D5EHS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS11915 ^@ http://purl.uniprot.org/uniprot/D5END9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/583355:CAKA_RS01280 ^@ http://purl.uniprot.org/uniprot/D5ELX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS11280 ^@ http://purl.uniprot.org/uniprot/D5EMP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS11525 ^@ http://purl.uniprot.org/uniprot/D5EMU7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS05980 ^@ http://purl.uniprot.org/uniprot/D5EIH7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS11560 ^@ http://purl.uniprot.org/uniprot/D5EMV5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS05905 ^@ http://purl.uniprot.org/uniprot/D5EIG2 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/583355:CAKA_RS07335 ^@ http://purl.uniprot.org/uniprot/D5EJA3 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/583355:CAKA_RS09485 ^@ http://purl.uniprot.org/uniprot/D5EKM0 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/583355:CAKA_RS11090 ^@ http://purl.uniprot.org/uniprot/D5EM88 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/583355:CAKA_RS14200 ^@ http://purl.uniprot.org/uniprot/D5EQQ5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS13435 ^@ http://purl.uniprot.org/uniprot/D5EPY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/583355:CAKA_RS12985 ^@ http://purl.uniprot.org/uniprot/D5EPB9 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/583355:CAKA_RS04400 ^@ http://purl.uniprot.org/uniprot/D5EQT3 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. http://togogenome.org/gene/583355:CAKA_RS14675 ^@ http://purl.uniprot.org/uniprot/D5ERB9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/583355:CAKA_RS05925 ^@ http://purl.uniprot.org/uniprot/D5EIG6 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/583355:CAKA_RS10325 ^@ http://purl.uniprot.org/uniprot/D5ELG2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS06920 ^@ http://purl.uniprot.org/uniprot/D5EJ23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS15895 ^@ http://purl.uniprot.org/uniprot/D5EHW5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS01660 ^@ http://purl.uniprot.org/uniprot/D5EMG7 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. http://togogenome.org/gene/583355:CAKA_RS11180 ^@ http://purl.uniprot.org/uniprot/D5EMA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS05090 ^@ http://purl.uniprot.org/uniprot/D5EHM9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/583355:CAKA_RS07585 ^@ http://purl.uniprot.org/uniprot/D5EJF3 ^@ Function|||Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.|||Catalyzes the biosynthesis of agmatine from arginine. http://togogenome.org/gene/583355:CAKA_RS15095 ^@ http://purl.uniprot.org/uniprot/D5EI10 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS14115 ^@ http://purl.uniprot.org/uniprot/D5EQN8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Homodimer.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.|||The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.|||The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity. http://togogenome.org/gene/583355:CAKA_RS09410 ^@ http://purl.uniprot.org/uniprot/D5EKK5 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/583355:CAKA_RS04160 ^@ http://purl.uniprot.org/uniprot/D5EQA7 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS13290 ^@ http://purl.uniprot.org/uniprot/D5EPV6 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/583355:CAKA_RS03165 ^@ http://purl.uniprot.org/uniprot/D5EPE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS09300 ^@ http://purl.uniprot.org/uniprot/D5EKE2 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/583355:CAKA_RS14920 ^@ http://purl.uniprot.org/uniprot/D5EHX3 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS12305 ^@ http://purl.uniprot.org/uniprot/D5ENL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS08985 ^@ http://purl.uniprot.org/uniprot/D5EK78 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/583355:CAKA_RS08330 ^@ http://purl.uniprot.org/uniprot/D5EJV1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/583355:CAKA_RS06515 ^@ http://purl.uniprot.org/uniprot/D5EIU0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/583355:CAKA_RS06975 ^@ http://purl.uniprot.org/uniprot/D5EJ34 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/583355:CAKA_RS10990 ^@ http://purl.uniprot.org/uniprot/D5EM69 ^@ Function|||Similarity ^@ Belongs to the GTP cyclohydrolase IV family.|||Converts GTP to 7,8-dihydroneopterin triphosphate. http://togogenome.org/gene/583355:CAKA_RS10300 ^@ http://purl.uniprot.org/uniprot/D5ELF5 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/583355:CAKA_RS14965 ^@ http://purl.uniprot.org/uniprot/D5EHY3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/583355:CAKA_RS14820 ^@ http://purl.uniprot.org/uniprot/D5ERF0 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/583355:CAKA_RS08680 ^@ http://purl.uniprot.org/uniprot/D5EK22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/583355:CAKA_RS13970 ^@ http://purl.uniprot.org/uniprot/D5EQK8 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/583355:CAKA_RS08880 ^@ http://purl.uniprot.org/uniprot/D5EK62 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/583355:CAKA_RS14105 ^@ http://purl.uniprot.org/uniprot/D5EQN6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Binds 1 [8Fe-7S] cluster per heterodimer.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/583355:CAKA_RS11235 ^@ http://purl.uniprot.org/uniprot/D5EMN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS06510 ^@ http://purl.uniprot.org/uniprot/D5EIT9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS08365 ^@ http://purl.uniprot.org/uniprot/D5EJV8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/583355:CAKA_RS01225 ^@ http://purl.uniprot.org/uniprot/D5ELW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III. http://togogenome.org/gene/583355:CAKA_RS12490 ^@ http://purl.uniprot.org/uniprot/D5EP20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS08670 ^@ http://purl.uniprot.org/uniprot/D5EK20 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/583355:CAKA_RS02210 ^@ http://purl.uniprot.org/uniprot/D5EN49 ^@ Function|||Similarity ^@ Belongs to the UxaE family.|||Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA). http://togogenome.org/gene/583355:CAKA_RS09165 ^@ http://purl.uniprot.org/uniprot/D5EKB5 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/583355:CAKA_RS13150 ^@ http://purl.uniprot.org/uniprot/D5EPT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS12750 ^@ http://purl.uniprot.org/uniprot/D5EP72 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/583355:CAKA_RS08325 ^@ http://purl.uniprot.org/uniprot/D5EJV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/583355:CAKA_RS11925 ^@ http://purl.uniprot.org/uniprot/D5ENE1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS08640 ^@ http://purl.uniprot.org/uniprot/D5EK14 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/583355:CAKA_RS13905 ^@ http://purl.uniprot.org/uniprot/D5EQJ5 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. http://togogenome.org/gene/583355:CAKA_RS06830 ^@ http://purl.uniprot.org/uniprot/D5EJ05 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS00750 ^@ http://purl.uniprot.org/uniprot/D5EL84 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/583355:CAKA_RS07985 ^@ http://purl.uniprot.org/uniprot/D5EJN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS08895 ^@ http://purl.uniprot.org/uniprot/D5EK65 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/583355:CAKA_RS15240 ^@ http://purl.uniprot.org/uniprot/D5EI41 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS13515 ^@ http://purl.uniprot.org/uniprot/D5EQ01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS15430 ^@ http://purl.uniprot.org/uniprot/D5EI84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS03980 ^@ http://purl.uniprot.org/uniprot/D5EQ72 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the KduI family.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. http://togogenome.org/gene/583355:CAKA_RS10130 ^@ http://purl.uniprot.org/uniprot/D5ELC1 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/583355:CAKA_RS15265 ^@ http://purl.uniprot.org/uniprot/D5EI46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS10035 ^@ http://purl.uniprot.org/uniprot/D5ELA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell inner membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS15700 ^@ http://purl.uniprot.org/uniprot/D5EN75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/583355:CAKA_RS12825 ^@ http://purl.uniprot.org/uniprot/D5EP87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/583355:CAKA_RS01985 ^@ http://purl.uniprot.org/uniprot/D5EN04 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/583355:CAKA_RS09180 ^@ http://purl.uniprot.org/uniprot/D5EKB8 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS07500 ^@ http://purl.uniprot.org/uniprot/D5EJD6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/583355:CAKA_RS01990 ^@ http://purl.uniprot.org/uniprot/D5EN05 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS00745 ^@ http://purl.uniprot.org/uniprot/D5EL83 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/583355:CAKA_RS08500 ^@ http://purl.uniprot.org/uniprot/D5EJY5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS06420 ^@ http://purl.uniprot.org/uniprot/D5EIS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/583355:CAKA_RS13375 ^@ http://purl.uniprot.org/uniprot/D5EPX3 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/583355:CAKA_RS07140 ^@ http://purl.uniprot.org/uniprot/D5EJ66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS07760 ^@ http://purl.uniprot.org/uniprot/D5EJI7 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/583355:CAKA_RS06275 ^@ http://purl.uniprot.org/uniprot/D5EIP3 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/583355:CAKA_RS01130 ^@ http://purl.uniprot.org/uniprot/D5ELU0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS14810 ^@ http://purl.uniprot.org/uniprot/D5ERE8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/583355:CAKA_RS15540 ^@ http://purl.uniprot.org/uniprot/D5EIM4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS03520 ^@ http://purl.uniprot.org/uniprot/D5EPL1 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/583355:CAKA_RS13400 ^@ http://purl.uniprot.org/uniprot/D5EPX8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/583355:CAKA_RS07350 ^@ http://purl.uniprot.org/uniprot/D5EJA6 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/583355:CAKA_RS00035 ^@ http://purl.uniprot.org/uniprot/D5EKF5 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/583355:CAKA_RS10225 ^@ http://purl.uniprot.org/uniprot/D5ELE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/583355:CAKA_RS11715 ^@ http://purl.uniprot.org/uniprot/D5EMY6 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS15085 ^@ http://purl.uniprot.org/uniprot/D5EI08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS12690 ^@ http://purl.uniprot.org/uniprot/D5EP60 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/583355:CAKA_RS06970 ^@ http://purl.uniprot.org/uniprot/D5EJ33 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/583355:CAKA_RS10240 ^@ http://purl.uniprot.org/uniprot/D5ELE3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/583355:CAKA_RS12500 ^@ http://purl.uniprot.org/uniprot/D5EP23 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/583355:CAKA_RS00245 ^@ http://purl.uniprot.org/uniprot/D5EKX6 ^@ Similarity ^@ Belongs to the aconitase/IPM isomerase family. http://togogenome.org/gene/583355:CAKA_RS14195 ^@ http://purl.uniprot.org/uniprot/D5EQQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/583355:CAKA_RS10840 ^@ http://purl.uniprot.org/uniprot/D5EM41 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS05110 ^@ http://purl.uniprot.org/uniprot/D5EHN3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS04640 ^@ http://purl.uniprot.org/uniprot/D5EQY4 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily. http://togogenome.org/gene/583355:CAKA_RS03455 ^@ http://purl.uniprot.org/uniprot/D5EPJ8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS13465 ^@ http://purl.uniprot.org/uniprot/D5EPZ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/583355:CAKA_RS06825 ^@ http://purl.uniprot.org/uniprot/D5EJ04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS13980 ^@ http://purl.uniprot.org/uniprot/D5EQL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/583355:CAKA_RS08905 ^@ http://purl.uniprot.org/uniprot/D5EK67 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS13730 ^@ http://purl.uniprot.org/uniprot/D5EQG2 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/583355:CAKA_RS03400 ^@ http://purl.uniprot.org/uniprot/D5EPI6 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/583355:CAKA_RS03000 ^@ http://purl.uniprot.org/uniprot/D5ENY9 ^@ Cofactor ^@ Binds 1 FAD per subunit.|||Binds 1 FMN per subunit. http://togogenome.org/gene/583355:CAKA_RS14835 ^@ http://purl.uniprot.org/uniprot/D5ERF3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS11410 ^@ http://purl.uniprot.org/uniprot/D5EMS5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS08570 ^@ http://purl.uniprot.org/uniprot/D5EJZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/583355:CAKA_RS01235 ^@ http://purl.uniprot.org/uniprot/D5ELW3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Cytoplasm|||Homodimer.|||Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS05850 ^@ http://purl.uniprot.org/uniprot/D5EIF2 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/583355:CAKA_RS02100 ^@ http://purl.uniprot.org/uniprot/D5EN26 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS10810 ^@ http://purl.uniprot.org/uniprot/D5EM36 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/583355:CAKA_RS08030 ^@ http://purl.uniprot.org/uniprot/D5EJP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS12720 ^@ http://purl.uniprot.org/uniprot/D5EP66 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/583355:CAKA_RS01095 ^@ http://purl.uniprot.org/uniprot/D5ELT2 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS08360 ^@ http://purl.uniprot.org/uniprot/D5EJV7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/583355:CAKA_RS05870 ^@ http://purl.uniprot.org/uniprot/D5EIF6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/583355:CAKA_RS10485 ^@ http://purl.uniprot.org/uniprot/D5ELJ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/583355:CAKA_RS12780 ^@ http://purl.uniprot.org/uniprot/D5EP78 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/583355:CAKA_RS04560 ^@ http://purl.uniprot.org/uniprot/D5EQW6 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/583355:CAKA_RS00780 ^@ http://purl.uniprot.org/uniprot/D5EL90 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/583355:CAKA_RS14825 ^@ http://purl.uniprot.org/uniprot/D5ERF1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/583355:CAKA_RS11995 ^@ http://purl.uniprot.org/uniprot/D5ENF5 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/583355:CAKA_RS09220 ^@ http://purl.uniprot.org/uniprot/D5EKC6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/583355:CAKA_RS05780 ^@ http://purl.uniprot.org/uniprot/D5EID8 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/583355:CAKA_RS12820 ^@ http://purl.uniprot.org/uniprot/D5EP86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS08775 ^@ http://purl.uniprot.org/uniprot/D5EK41 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/583355:CAKA_RS11670 ^@ http://purl.uniprot.org/uniprot/D5EMX7 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/583355:CAKA_RS03380 ^@ http://purl.uniprot.org/uniprot/D5EPI2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/583355:CAKA_RS06815 ^@ http://purl.uniprot.org/uniprot/D5EJ02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS09965 ^@ http://purl.uniprot.org/uniprot/D5EKW6 ^@ Similarity ^@ Belongs to the radical SAM superfamily. KamA family. http://togogenome.org/gene/583355:CAKA_RS13190 ^@ http://purl.uniprot.org/uniprot/D5EPT7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/583355:CAKA_RS10185 ^@ http://purl.uniprot.org/uniprot/D5ELD2 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/583355:CAKA_RS10675 ^@ http://purl.uniprot.org/uniprot/D5EM09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS10210 ^@ http://purl.uniprot.org/uniprot/D5ELD7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/583355:CAKA_RS04600 ^@ http://purl.uniprot.org/uniprot/D5EQX5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/583355:CAKA_RS13455 ^@ http://purl.uniprot.org/uniprot/D5EPY8 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/583355:CAKA_RS08370 ^@ http://purl.uniprot.org/uniprot/D5EJV9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/583355:CAKA_RS08870 ^@ http://purl.uniprot.org/uniprot/D5EK60 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/583355:CAKA_RS12395 ^@ http://purl.uniprot.org/uniprot/D5ENN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS11295 ^@ http://purl.uniprot.org/uniprot/D5EMP9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/583355:CAKA_RS01045 ^@ http://purl.uniprot.org/uniprot/D5ELS2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/583355:CAKA_RS14100 ^@ http://purl.uniprot.org/uniprot/D5EQN5 ^@ Function|||Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family.|||This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). http://togogenome.org/gene/583355:CAKA_RS02890 ^@ http://purl.uniprot.org/uniprot/D5ENW6 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS14900 ^@ http://purl.uniprot.org/uniprot/D5EHW9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/583355:CAKA_RS07690 ^@ http://purl.uniprot.org/uniprot/D5EJH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS00765 ^@ http://purl.uniprot.org/uniprot/D5EL87 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS14750 ^@ http://purl.uniprot.org/uniprot/D5ERD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/583355:CAKA_RS07695 ^@ http://purl.uniprot.org/uniprot/D5EJH3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS05670 ^@ http://purl.uniprot.org/uniprot/D5EIB7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS14165 ^@ http://purl.uniprot.org/uniprot/D5EQP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS08250 ^@ http://purl.uniprot.org/uniprot/D5EJT5 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/583355:CAKA_RS03865 ^@ http://purl.uniprot.org/uniprot/D5EQ49 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS07935 ^@ http://purl.uniprot.org/uniprot/D5EJM3 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/583355:CAKA_RS03940 ^@ http://purl.uniprot.org/uniprot/D5EQ64 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/583355:CAKA_RS07365 ^@ http://purl.uniprot.org/uniprot/D5EJB0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS12140 ^@ http://purl.uniprot.org/uniprot/D5ENI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS01155 ^@ http://purl.uniprot.org/uniprot/D5ELU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS07800 ^@ http://purl.uniprot.org/uniprot/D5EJJ6 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/583355:CAKA_RS14755 ^@ http://purl.uniprot.org/uniprot/D5ERD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/583355:CAKA_RS01065 ^@ http://purl.uniprot.org/uniprot/D5ELS6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/583355:CAKA_RS12000 ^@ http://purl.uniprot.org/uniprot/D5ENF6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS09090 ^@ http://purl.uniprot.org/uniprot/D5EK99 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/583355:CAKA_RS10385 ^@ http://purl.uniprot.org/uniprot/D5ELH4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS05910 ^@ http://purl.uniprot.org/uniprot/D5EIG3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS11050 ^@ http://purl.uniprot.org/uniprot/D5EM80 ^@ Activity Regulation|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/583355:CAKA_RS10785 ^@ http://purl.uniprot.org/uniprot/D5EM31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.|||Catalyzes the sodium-dependent transport of glutamate.|||Cell inner membrane http://togogenome.org/gene/583355:CAKA_RS00050 ^@ http://purl.uniprot.org/uniprot/D5EKF8 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/583355:CAKA_RS06545 ^@ http://purl.uniprot.org/uniprot/D5EIU6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS11860 ^@ http://purl.uniprot.org/uniprot/D5ENC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS13770 ^@ http://purl.uniprot.org/uniprot/D5EQH0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/583355:CAKA_RS00785 ^@ http://purl.uniprot.org/uniprot/D5ELL8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/583355:CAKA_RS11730 ^@ http://purl.uniprot.org/uniprot/D5EMY9 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/583355:CAKA_RS12260 ^@ http://purl.uniprot.org/uniprot/D5ENK7 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/583355:CAKA_RS01750 ^@ http://purl.uniprot.org/uniprot/D5EMI6 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS05375 ^@ http://purl.uniprot.org/uniprot/D5EHT6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/583355:CAKA_RS00380 ^@ http://purl.uniprot.org/uniprot/D5EL05 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS09010 ^@ http://purl.uniprot.org/uniprot/D5EK83 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS12450 ^@ http://purl.uniprot.org/uniprot/D5EP12 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS11160 ^@ http://purl.uniprot.org/uniprot/D5EMA1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/583355:CAKA_RS08975 ^@ http://purl.uniprot.org/uniprot/D5EK76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS09085 ^@ http://purl.uniprot.org/uniprot/D5EK98 ^@ Cofactor|||Similarity ^@ Belongs to the ApbE family.|||Magnesium. Can also use manganese. http://togogenome.org/gene/583355:CAKA_RS14190 ^@ http://purl.uniprot.org/uniprot/D5EQQ3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS05395 ^@ http://purl.uniprot.org/uniprot/D5EHU0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS08490 ^@ http://purl.uniprot.org/uniprot/D5EJY3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/583355:CAKA_RS15040 ^@ http://purl.uniprot.org/uniprot/D5EHZ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS08915 ^@ http://purl.uniprot.org/uniprot/D5EK69 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/583355:CAKA_RS06310 ^@ http://purl.uniprot.org/uniprot/D5EIQ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS10010 ^@ http://purl.uniprot.org/uniprot/D5EL97 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/583355:CAKA_RS11485 ^@ http://purl.uniprot.org/uniprot/D5EMT9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/583355:CAKA_RS08170 ^@ http://purl.uniprot.org/uniprot/D5EJS0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/583355:CAKA_RS01580 ^@ http://purl.uniprot.org/uniprot/D5EMF1 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/583355:CAKA_RS07020 ^@ http://purl.uniprot.org/uniprot/D5EJ43 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/583355:CAKA_RS03145 ^@ http://purl.uniprot.org/uniprot/D5EPD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS10220 ^@ http://purl.uniprot.org/uniprot/D5ELD9 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS16795 ^@ http://purl.uniprot.org/uniprot/D5ELN2 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/583355:CAKA_RS14970 ^@ http://purl.uniprot.org/uniprot/D5EHY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS05050 ^@ http://purl.uniprot.org/uniprot/D5EHM1 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS10715 ^@ http://purl.uniprot.org/uniprot/D5EM17 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/583355:CAKA_RS00200 ^@ http://purl.uniprot.org/uniprot/D5EKI9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS13305 ^@ http://purl.uniprot.org/uniprot/D5EPV9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS05310 ^@ http://purl.uniprot.org/uniprot/D5EHS3 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/583355:CAKA_RS07950 ^@ http://purl.uniprot.org/uniprot/D5EJM6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS03410 ^@ http://purl.uniprot.org/uniprot/D5EPI9 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/583355:CAKA_RS09005 ^@ http://purl.uniprot.org/uniprot/D5EK82 ^@ Cofactor|||Similarity ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/583355:CAKA_RS14500 ^@ http://purl.uniprot.org/uniprot/D5ER85 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/583355:CAKA_RS01120 ^@ http://purl.uniprot.org/uniprot/D5ELT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS06755 ^@ http://purl.uniprot.org/uniprot/D5EIY8 ^@ Cofactor|||Similarity ^@ Belongs to the truncated hemoglobin family. Group I subfamily.|||Binds 1 heme group per subunit. http://togogenome.org/gene/583355:CAKA_RS11680 ^@ http://purl.uniprot.org/uniprot/D5EMX9 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/583355:CAKA_RS11920 ^@ http://purl.uniprot.org/uniprot/D5ENE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OmpP1/FadL family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS04080 ^@ http://purl.uniprot.org/uniprot/D5EQ91 ^@ Function ^@ Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/583355:CAKA_RS08750 ^@ http://purl.uniprot.org/uniprot/D5EK37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS06560 ^@ http://purl.uniprot.org/uniprot/D5EIU9 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/583355:CAKA_RS00775 ^@ http://purl.uniprot.org/uniprot/D5EL89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS03255 ^@ http://purl.uniprot.org/uniprot/D5EPG1 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/583355:CAKA_RS14230 ^@ http://purl.uniprot.org/uniprot/D5EQQ9 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/583355:CAKA_RS08540 ^@ http://purl.uniprot.org/uniprot/D5EJZ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS09795 ^@ http://purl.uniprot.org/uniprot/D5EKT2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS10505 ^@ http://purl.uniprot.org/uniprot/D5ELJ8 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/583355:CAKA_RS06945 ^@ http://purl.uniprot.org/uniprot/D5EJ28 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/583355:CAKA_RS04445 ^@ http://purl.uniprot.org/uniprot/D5EQU2 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/583355:CAKA_RS04190 ^@ http://purl.uniprot.org/uniprot/D5EQB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS04390 ^@ http://purl.uniprot.org/uniprot/D5EQT1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/583355:CAKA_RS10365 ^@ http://purl.uniprot.org/uniprot/D5ELH0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/583355:CAKA_RS05815 ^@ http://purl.uniprot.org/uniprot/D5EIE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS07620 ^@ http://purl.uniprot.org/uniprot/D5EJG0 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/583355:CAKA_RS01125 ^@ http://purl.uniprot.org/uniprot/D5ELT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS09785 ^@ http://purl.uniprot.org/uniprot/D5EKT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS14910 ^@ http://purl.uniprot.org/uniprot/D5EHX1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/583355:CAKA_RS11895 ^@ http://purl.uniprot.org/uniprot/D5END5 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/583355:CAKA_RS00770 ^@ http://purl.uniprot.org/uniprot/D5EL88 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/583355:CAKA_RS07485 ^@ http://purl.uniprot.org/uniprot/D5EJD3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell inner membrane|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/583355:CAKA_RS06745 ^@ http://purl.uniprot.org/uniprot/D5EIY5 ^@ Similarity ^@ Belongs to the cytochrome c-552 family. http://togogenome.org/gene/583355:CAKA_RS10475 ^@ http://purl.uniprot.org/uniprot/D5ELJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/583355:CAKA_RS10095 ^@ http://purl.uniprot.org/uniprot/D5ELB4 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/583355:CAKA_RS09155 ^@ http://purl.uniprot.org/uniprot/D5EKB3 ^@ Function ^@ The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. http://togogenome.org/gene/583355:CAKA_RS08995 ^@ http://purl.uniprot.org/uniprot/D5EK80 ^@ Cofactor|||Subunit ^@ Binds 1 zinc ion.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS07370 ^@ http://purl.uniprot.org/uniprot/D5EJB1 ^@ Similarity ^@ Belongs to the MYG1 family. http://togogenome.org/gene/583355:CAKA_RS02105 ^@ http://purl.uniprot.org/uniprot/D5EN27 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/583355:CAKA_RS05095 ^@ http://purl.uniprot.org/uniprot/D5EHN0 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/583355:CAKA_RS11060 ^@ http://purl.uniprot.org/uniprot/D5EM82 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/583355:CAKA_RS05785 ^@ http://purl.uniprot.org/uniprot/D5EID9 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/583355:CAKA_RS12110 ^@ http://purl.uniprot.org/uniprot/D5ENH8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/583355:CAKA_RS07820 ^@ http://purl.uniprot.org/uniprot/D5EJK0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS01995 ^@ http://purl.uniprot.org/uniprot/D5EN06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS13595 ^@ http://purl.uniprot.org/uniprot/D5EQ17 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS15555 ^@ http://purl.uniprot.org/uniprot/D5EIM8 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/583355:CAKA_RS04130 ^@ http://purl.uniprot.org/uniprot/D5EQA1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS10500 ^@ http://purl.uniprot.org/uniprot/D5ELJ7 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/583355:CAKA_RS01170 ^@ http://purl.uniprot.org/uniprot/D5ELU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS05170 ^@ http://purl.uniprot.org/uniprot/D5EHP6 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/583355:CAKA_RS07980 ^@ http://purl.uniprot.org/uniprot/D5EJN2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/583355:CAKA_RS01890 ^@ http://purl.uniprot.org/uniprot/D5EML4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS09280 ^@ http://purl.uniprot.org/uniprot/D5EKD8 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/583355:CAKA_RS03635 ^@ http://purl.uniprot.org/uniprot/D5EPN5 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/583355:CAKA_RS04450 ^@ http://purl.uniprot.org/uniprot/D5EQU3 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/583355:CAKA_RS02055 ^@ http://purl.uniprot.org/uniprot/D5EN17 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS10480 ^@ http://purl.uniprot.org/uniprot/D5ELJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/583355:CAKA_RS12740 ^@ http://purl.uniprot.org/uniprot/D5EP69 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/583355:CAKA_RS12045 ^@ http://purl.uniprot.org/uniprot/D5ENG5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS14075 ^@ http://purl.uniprot.org/uniprot/D5EQN0 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/583355:CAKA_RS10440 ^@ http://purl.uniprot.org/uniprot/D5ELI5 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS11685 ^@ http://purl.uniprot.org/uniprot/D5EMY0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/583355:CAKA_RS09245 ^@ http://purl.uniprot.org/uniprot/D5EKD1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS02145 ^@ http://purl.uniprot.org/uniprot/D5EN35 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/583355:CAKA_RS06940 ^@ http://purl.uniprot.org/uniprot/D5EJ27 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/583355:CAKA_RS13270 ^@ http://purl.uniprot.org/uniprot/D5EPV2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/583355:CAKA_RS09405 ^@ http://purl.uniprot.org/uniprot/D5EKK4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS11835 ^@ http://purl.uniprot.org/uniprot/D5ENC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS01265 ^@ http://purl.uniprot.org/uniprot/D5ELW9 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/583355:CAKA_RS00520 ^@ http://purl.uniprot.org/uniprot/D5EL35 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/583355:CAKA_RS12745 ^@ http://purl.uniprot.org/uniprot/D5EP71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS12005 ^@ http://purl.uniprot.org/uniprot/D5ENF7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS09050 ^@ http://purl.uniprot.org/uniprot/D5EK91 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/583355:CAKA_RS09355 ^@ http://purl.uniprot.org/uniprot/D5EKJ5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/583355:CAKA_RS12570 ^@ http://purl.uniprot.org/uniprot/D5EP36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS02045 ^@ http://purl.uniprot.org/uniprot/D5EN15 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS04430 ^@ http://purl.uniprot.org/uniprot/D5EQT9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/583355:CAKA_RS12430 ^@ http://purl.uniprot.org/uniprot/D5ENP1 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/583355:CAKA_RS08320 ^@ http://purl.uniprot.org/uniprot/D5EJU9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/583355:CAKA_RS04205 ^@ http://purl.uniprot.org/uniprot/D5EQB6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/583355:CAKA_RS08255 ^@ http://purl.uniprot.org/uniprot/D5EJT6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/583355:CAKA_RS00195 ^@ http://purl.uniprot.org/uniprot/D5EKI8 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/583355:CAKA_RS07075 ^@ http://purl.uniprot.org/uniprot/D5EJ54 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/583355:CAKA_RS12365 ^@ http://purl.uniprot.org/uniprot/D5ENM8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS01980 ^@ http://purl.uniprot.org/uniprot/D5EMN2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/583355:CAKA_RS04355 ^@ http://purl.uniprot.org/uniprot/D5EQS2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/583355:CAKA_RS06555 ^@ http://purl.uniprot.org/uniprot/D5EIU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS00760 ^@ http://purl.uniprot.org/uniprot/D5EL86 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/583355:CAKA_RS13445 ^@ http://purl.uniprot.org/uniprot/D5EPY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/583355:CAKA_RS09040 ^@ http://purl.uniprot.org/uniprot/D5EK89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS12160 ^@ http://purl.uniprot.org/uniprot/D5ENI7 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/583355:CAKA_RS04050 ^@ http://purl.uniprot.org/uniprot/D5EQ86 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/583355:CAKA_RS01185 ^@ http://purl.uniprot.org/uniprot/D5ELV2 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/583355:CAKA_RS11990 ^@ http://purl.uniprot.org/uniprot/D5ENF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS04335 ^@ http://purl.uniprot.org/uniprot/D5EQE3 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/583355:CAKA_RS11630 ^@ http://purl.uniprot.org/uniprot/D5EMW9 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/583355:CAKA_RS15055 ^@ http://purl.uniprot.org/uniprot/D5EI02 ^@ Similarity ^@ Belongs to the UPRTase family. http://togogenome.org/gene/583355:CAKA_RS10235 ^@ http://purl.uniprot.org/uniprot/D5ELE2 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/583355:CAKA_RS07230 ^@ http://purl.uniprot.org/uniprot/D5EJ83 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Binds 1 copper ion per subunit, denoted as copper B.|||Binds 2 heme groups per subunit, denoted as high- and low-spin.|||Membrane http://togogenome.org/gene/583355:CAKA_RS12980 ^@ http://purl.uniprot.org/uniprot/D5EPB8 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/583355:CAKA_RS08235 ^@ http://purl.uniprot.org/uniprot/D5EJT2 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/583355:CAKA_RS09755 ^@ http://purl.uniprot.org/uniprot/D5EKS4 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/583355:CAKA_RS05485 ^@ http://purl.uniprot.org/uniprot/D5EHV8 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/583355:CAKA_RS14880 ^@ http://purl.uniprot.org/uniprot/D5ERG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/583355:CAKA_RS12510 ^@ http://purl.uniprot.org/uniprot/D5EP25 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/583355:CAKA_RS10670 ^@ http://purl.uniprot.org/uniprot/D5EM08 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS12340 ^@ http://purl.uniprot.org/uniprot/D5ENM3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/583355:CAKA_RS12960 ^@ http://purl.uniprot.org/uniprot/D5EPB4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/583355:CAKA_RS16015 ^@ http://purl.uniprot.org/uniprot/D5EJL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS07120 ^@ http://purl.uniprot.org/uniprot/D5EJ62 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS12300 ^@ http://purl.uniprot.org/uniprot/D5ENL5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell inner membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/583355:CAKA_RS05160 ^@ http://purl.uniprot.org/uniprot/D5EHP4 ^@ Similarity ^@ Belongs to the ATP:guanido phosphotransferase family. http://togogenome.org/gene/583355:CAKA_RS06335 ^@ http://purl.uniprot.org/uniprot/D5EIQ5 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily. http://togogenome.org/gene/583355:CAKA_RS03370 ^@ http://purl.uniprot.org/uniprot/D5EPI0 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/583355:CAKA_RS10540 ^@ http://purl.uniprot.org/uniprot/D5ELK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS01835 ^@ http://purl.uniprot.org/uniprot/D5EMK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS03575 ^@ http://purl.uniprot.org/uniprot/D5EPM3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/583355:CAKA_RS09790 ^@ http://purl.uniprot.org/uniprot/D5EKT1 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/583355:CAKA_RS10455 ^@ http://purl.uniprot.org/uniprot/D5ELI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS14530 ^@ http://purl.uniprot.org/uniprot/D5ER91 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily. http://togogenome.org/gene/583355:CAKA_RS05215 ^@ http://purl.uniprot.org/uniprot/D5EHQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.|||Cell membrane|||Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/583355:CAKA_RS10695 ^@ http://purl.uniprot.org/uniprot/D5EM13 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/583355:CAKA_RS11055 ^@ http://purl.uniprot.org/uniprot/D5EM81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS01775 ^@ http://purl.uniprot.org/uniprot/D5EMJ1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/583355:CAKA_RS03550 ^@ http://purl.uniprot.org/uniprot/D5EPL7 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/583355:CAKA_RS03920 ^@ http://purl.uniprot.org/uniprot/D5EQ60 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/583355:CAKA_RS12585 ^@ http://purl.uniprot.org/uniprot/D5EP40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS10690 ^@ http://purl.uniprot.org/uniprot/D5EM12 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/583355:CAKA_RS04440 ^@ http://purl.uniprot.org/uniprot/D5EQU1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/583355:CAKA_RS08950 ^@ http://purl.uniprot.org/uniprot/D5EK71 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/583355:CAKA_RS03555 ^@ http://purl.uniprot.org/uniprot/D5EPL8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/583355:CAKA_RS09370 ^@ http://purl.uniprot.org/uniprot/D5EKJ8 ^@ Function|||Similarity ^@ Belongs to the LarC family.|||Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. http://togogenome.org/gene/583355:CAKA_RS03570 ^@ http://purl.uniprot.org/uniprot/D5EPM2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/583355:CAKA_RS15925 ^@ http://purl.uniprot.org/uniprot/D5EIK2 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/583355:CAKA_RS12335 ^@ http://purl.uniprot.org/uniprot/D5ENM2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/583355:CAKA_RS05195 ^@ http://purl.uniprot.org/uniprot/D5EHQ0 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/583355:CAKA_RS12280 ^@ http://purl.uniprot.org/uniprot/D5ENL1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS11025 ^@ http://purl.uniprot.org/uniprot/D5EM76 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/583355:CAKA_RS16115 ^@ http://purl.uniprot.org/uniprot/D5EKV6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS14700 ^@ http://purl.uniprot.org/uniprot/D5ERC4 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/583355:CAKA_RS09470 ^@ http://purl.uniprot.org/uniprot/D5EKL7 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/583355:CAKA_RS02930 ^@ http://purl.uniprot.org/uniprot/D5ENX5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/583355:CAKA_RS11950 ^@ http://purl.uniprot.org/uniprot/D5ENE6 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/583355:CAKA_RS10770 ^@ http://purl.uniprot.org/uniprot/D5EM28 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/583355:CAKA_RS02365 ^@ http://purl.uniprot.org/uniprot/D5EN80 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 16 family. http://togogenome.org/gene/583355:CAKA_RS13650 ^@ http://purl.uniprot.org/uniprot/D5EQ26 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/583355:CAKA_RS08040 ^@ http://purl.uniprot.org/uniprot/D5EJP4 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/583355:CAKA_RS10930 ^@ http://purl.uniprot.org/uniprot/D5EM57 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS07270 ^@ http://purl.uniprot.org/uniprot/D5EJ92 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/583355:CAKA_RS08095 ^@ http://purl.uniprot.org/uniprot/D5EJQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP G family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS09660 ^@ http://purl.uniprot.org/uniprot/D5EKQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/583355:CAKA_RS12775 ^@ http://purl.uniprot.org/uniprot/D5EP77 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/583355:CAKA_RS00360 ^@ http://purl.uniprot.org/uniprot/D5EL01 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/583355:CAKA_RS12910 ^@ http://purl.uniprot.org/uniprot/D5EPA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/583355:CAKA_RS06105 ^@ http://purl.uniprot.org/uniprot/D5EIJ5 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/583355:CAKA_RS00005 ^@ http://purl.uniprot.org/uniprot/D5EKE9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/583355:CAKA_RS03870 ^@ http://purl.uniprot.org/uniprot/D5EQ50 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/583355:CAKA_RS08230 ^@ http://purl.uniprot.org/uniprot/D5EJT1 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/583355:CAKA_RS11580 ^@ http://purl.uniprot.org/uniprot/D5EMV9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/583355:CAKA_RS03990 ^@ http://purl.uniprot.org/uniprot/D5EQ74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS00285 ^@ http://purl.uniprot.org/uniprot/D5EKY6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 16 family. http://togogenome.org/gene/583355:CAKA_RS16885 ^@ http://purl.uniprot.org/uniprot/D5EMP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/583355:CAKA_RS08345 ^@ http://purl.uniprot.org/uniprot/D5EJV4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/583355:CAKA_RS15270 ^@ http://purl.uniprot.org/uniprot/D5EI47 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS07050 ^@ http://purl.uniprot.org/uniprot/D5EJ49 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the CobB/CobQ family.|||Involved in acetate metabolism.|||The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site. http://togogenome.org/gene/583355:CAKA_RS13175 ^@ http://purl.uniprot.org/uniprot/D5EPT4 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/583355:CAKA_RS04040 ^@ http://purl.uniprot.org/uniprot/D5EQ84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS10205 ^@ http://purl.uniprot.org/uniprot/D5ELD6 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/583355:CAKA_RS03900 ^@ http://purl.uniprot.org/uniprot/D5EQ56 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/583355:CAKA_RS03515 ^@ http://purl.uniprot.org/uniprot/D5EPL0 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/583355:CAKA_RS11130 ^@ http://purl.uniprot.org/uniprot/D5EM96 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS16205 ^@ http://purl.uniprot.org/uniprot/D5EMP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS02020 ^@ http://purl.uniprot.org/uniprot/D5EN10 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily. http://togogenome.org/gene/583355:CAKA_RS04350 ^@ http://purl.uniprot.org/uniprot/D5EQE6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/583355:CAKA_RS07305 ^@ http://purl.uniprot.org/uniprot/D5EJ99 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/583355:CAKA_RS00795 ^@ http://purl.uniprot.org/uniprot/D5ELM0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/583355:CAKA_RS14955 ^@ http://purl.uniprot.org/uniprot/D5EHY0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/583355:CAKA_RS08860 ^@ http://purl.uniprot.org/uniprot/D5EK58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/583355:CAKA_RS01605 ^@ http://purl.uniprot.org/uniprot/D5EMF6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/583355:CAKA_RS12015 ^@ http://purl.uniprot.org/uniprot/D5ENF9 ^@ Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. http://togogenome.org/gene/583355:CAKA_RS03150 ^@ http://purl.uniprot.org/uniprot/D5EPE0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS12115 ^@ http://purl.uniprot.org/uniprot/D5ENH9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS18 family. http://togogenome.org/gene/583355:CAKA_RS12080 ^@ http://purl.uniprot.org/uniprot/D5ENH2 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS04105 ^@ http://purl.uniprot.org/uniprot/D5EQ96 ^@ Caution|||Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS05475 ^@ http://purl.uniprot.org/uniprot/D5EHV6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/583355:CAKA_RS14035 ^@ http://purl.uniprot.org/uniprot/D5EQM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS11275 ^@ http://purl.uniprot.org/uniprot/D5EMP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/583355:CAKA_RS11340 ^@ http://purl.uniprot.org/uniprot/D5EMR0 ^@ Similarity ^@ Belongs to the AIR synthase family. http://togogenome.org/gene/583355:CAKA_RS05200 ^@ http://purl.uniprot.org/uniprot/D5EHQ1 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/583355:CAKA_RS03260 ^@ http://purl.uniprot.org/uniprot/D5EPG2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS07810 ^@ http://purl.uniprot.org/uniprot/D5EJJ8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS00595 ^@ http://purl.uniprot.org/uniprot/D5EL51 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/583355:CAKA_RS14280 ^@ http://purl.uniprot.org/uniprot/D5EQR9 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/583355:CAKA_RS07975 ^@ http://purl.uniprot.org/uniprot/D5EJN1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxC family.|||Belongs to the thioester dehydratase family. FabZ subfamily.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/583355:CAKA_RS05105 ^@ http://purl.uniprot.org/uniprot/D5EHN2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/583355:CAKA_RS15260 ^@ http://purl.uniprot.org/uniprot/D5EI45 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell inner membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS03745 ^@ http://purl.uniprot.org/uniprot/D5EQ28 ^@ Similarity ^@ Belongs to the acetyltransferase family. ArgA subfamily. http://togogenome.org/gene/583355:CAKA_RS13450 ^@ http://purl.uniprot.org/uniprot/D5EPY7 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/583355:CAKA_RS07090 ^@ http://purl.uniprot.org/uniprot/D5EJ57 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/583355:CAKA_RS13030 ^@ http://purl.uniprot.org/uniprot/D5EPC8 ^@ Similarity ^@ Belongs to the OprB family. http://togogenome.org/gene/583355:CAKA_RS01000 ^@ http://purl.uniprot.org/uniprot/D5ELR3 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/583355:CAKA_RS16985 ^@ http://purl.uniprot.org/uniprot/D5EM00 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/583355:CAKA_RS00550 ^@ http://purl.uniprot.org/uniprot/D5EL41 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/583355:CAKA_RS13460 ^@ http://purl.uniprot.org/uniprot/D5EPY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/583355:CAKA_RS15080 ^@ http://purl.uniprot.org/uniprot/D5EI07 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/583355:CAKA_RS01925 ^@ http://purl.uniprot.org/uniprot/D5EMM1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS08335 ^@ http://purl.uniprot.org/uniprot/D5EJV2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/583355:CAKA_RS03705 ^@ http://purl.uniprot.org/uniprot/D5EPQ1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS07215 ^@ http://purl.uniprot.org/uniprot/D5EJ79 ^@ Function ^@ Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. http://togogenome.org/gene/583355:CAKA_RS08875 ^@ http://purl.uniprot.org/uniprot/D5EK61 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/583355:CAKA_RS15120 ^@ http://purl.uniprot.org/uniprot/D5EI15 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/583355:CAKA_RS09715 ^@ http://purl.uniprot.org/uniprot/D5EKR6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/583355:CAKA_RS05835 ^@ http://purl.uniprot.org/uniprot/D5EIE9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS03005 ^@ http://purl.uniprot.org/uniprot/D5ENZ0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.|||Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Binds 1 siroheme per subunit.|||Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. http://togogenome.org/gene/583355:CAKA_RS14515 ^@ http://purl.uniprot.org/uniprot/D5ER88 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).|||Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Cell inner membrane|||Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/583355:CAKA_RS00755 ^@ http://purl.uniprot.org/uniprot/D5EL85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS08155 ^@ http://purl.uniprot.org/uniprot/D5EJR7 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/583355:CAKA_RS14870 ^@ http://purl.uniprot.org/uniprot/D5ERG0 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/583355:CAKA_RS05565 ^@ http://purl.uniprot.org/uniprot/D5EI98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS05220 ^@ http://purl.uniprot.org/uniprot/D5EHQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/583355:CAKA_RS12900 ^@ http://purl.uniprot.org/uniprot/D5EPA2 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS07630 ^@ http://purl.uniprot.org/uniprot/D5EJG1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/583355:CAKA_RS15050 ^@ http://purl.uniprot.org/uniprot/D5EI01 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/583355:CAKA_RS02435 ^@ http://purl.uniprot.org/uniprot/D5EN94 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS07460 ^@ http://purl.uniprot.org/uniprot/D5EJC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS07830 ^@ http://purl.uniprot.org/uniprot/D5EJK2 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/583355:CAKA_RS07055 ^@ http://purl.uniprot.org/uniprot/D5EJ50 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/583355:CAKA_RS06400 ^@ http://purl.uniprot.org/uniprot/D5EIR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS00815 ^@ http://purl.uniprot.org/uniprot/D5ELM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS01625 ^@ http://purl.uniprot.org/uniprot/D5EMG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/583355:CAKA_RS04175 ^@ http://purl.uniprot.org/uniprot/D5EQA9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/583355:CAKA_RS07475 ^@ http://purl.uniprot.org/uniprot/D5EJD1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/583355:CAKA_RS09120 ^@ http://purl.uniprot.org/uniprot/D5EKA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS14975 ^@ http://purl.uniprot.org/uniprot/D5EHY5 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/583355:CAKA_RS01735 ^@ http://purl.uniprot.org/uniprot/D5EMI3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 16 family. http://togogenome.org/gene/583355:CAKA_RS15645 ^@ http://purl.uniprot.org/uniprot/D5ELX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/583355:CAKA_RS13740 ^@ http://purl.uniprot.org/uniprot/D5EQG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS03160 ^@ http://purl.uniprot.org/uniprot/D5EPE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS08315 ^@ http://purl.uniprot.org/uniprot/D5EJU8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/583355:CAKA_RS09095 ^@ http://purl.uniprot.org/uniprot/D5EKA0 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/583355:CAKA_RS11205 ^@ http://purl.uniprot.org/uniprot/D5EMB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS11325 ^@ http://purl.uniprot.org/uniprot/D5EMQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family.|||Cell outer membrane http://togogenome.org/gene/583355:CAKA_RS12415 ^@ http://purl.uniprot.org/uniprot/D5ENN8 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/583355:CAKA_RS09345 ^@ http://purl.uniprot.org/uniprot/D5EKJ3 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/583355:CAKA_RS15785 ^@ http://purl.uniprot.org/uniprot/D5EPQ3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS13705 ^@ http://purl.uniprot.org/uniprot/D5EQF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS08735 ^@ http://purl.uniprot.org/uniprot/D5EK34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS09550 ^@ http://purl.uniprot.org/uniprot/D5EKN3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS03450 ^@ http://purl.uniprot.org/uniprot/D5EPJ7 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/583355:CAKA_RS11725 ^@ http://purl.uniprot.org/uniprot/D5EMY8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/583355:CAKA_RS08265 ^@ http://purl.uniprot.org/uniprot/D5EJT8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/583355:CAKA_RS05455 ^@ http://purl.uniprot.org/uniprot/D5EHV2 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/583355:CAKA_RS15065 ^@ http://purl.uniprot.org/uniprot/D5EI04 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/583355:CAKA_RS02910 ^@ http://purl.uniprot.org/uniprot/D5ENX1 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS00975 ^@ http://purl.uniprot.org/uniprot/D5ELQ8 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/583355:CAKA_RS02000 ^@ http://purl.uniprot.org/uniprot/D5EN07 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS14300 ^@ http://purl.uniprot.org/uniprot/D5ER45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS10585 ^@ http://purl.uniprot.org/uniprot/D5ELL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/583355:CAKA_RS05620 ^@ http://purl.uniprot.org/uniprot/D5EIA7 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/583355:CAKA_RS00800 ^@ http://purl.uniprot.org/uniprot/D5ELM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS09480 ^@ http://purl.uniprot.org/uniprot/D5EKL9 ^@ Similarity ^@ Belongs to the UDPGP type 1 family. http://togogenome.org/gene/583355:CAKA_RS14735 ^@ http://purl.uniprot.org/uniprot/D5ERD2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/583355:CAKA_RS02590 ^@ http://purl.uniprot.org/uniprot/D5ENQ3 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/583355:CAKA_RS05860 ^@ http://purl.uniprot.org/uniprot/D5EIF4 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/583355:CAKA_RS06635 ^@ http://purl.uniprot.org/uniprot/D5EIW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS10075 ^@ http://purl.uniprot.org/uniprot/D5ELB0 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/583355:CAKA_RS03125 ^@ http://purl.uniprot.org/uniprot/D5EPD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS09335 ^@ http://purl.uniprot.org/uniprot/D5EKJ1 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/583355:CAKA_RS08510 ^@ http://purl.uniprot.org/uniprot/D5EJY7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/583355:CAKA_RS00620 ^@ http://purl.uniprot.org/uniprot/D5EL57 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS11125 ^@ http://purl.uniprot.org/uniprot/D5EM95 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS12505 ^@ http://purl.uniprot.org/uniprot/D5EP24 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/583355:CAKA_RS09210 ^@ http://purl.uniprot.org/uniprot/D5EKC4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/583355:CAKA_RS05735 ^@ http://purl.uniprot.org/uniprot/D5EIC9 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/583355:CAKA_RS04135 ^@ http://purl.uniprot.org/uniprot/D5EQA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/583355:CAKA_RS08280 ^@ http://purl.uniprot.org/uniprot/D5EJU1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/583355:CAKA_RS08460 ^@ http://purl.uniprot.org/uniprot/D5EJX7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/583355:CAKA_RS02570 ^@ http://purl.uniprot.org/uniprot/D5ENP8 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS14850 ^@ http://purl.uniprot.org/uniprot/D5ERF6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS14915 ^@ http://purl.uniprot.org/uniprot/D5EHX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS04425 ^@ http://purl.uniprot.org/uniprot/D5EQT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS12195 ^@ http://purl.uniprot.org/uniprot/D5ENJ5 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/583355:CAKA_RS06505 ^@ http://purl.uniprot.org/uniprot/D5EIT8 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/583355:CAKA_RS11380 ^@ http://purl.uniprot.org/uniprot/D5EMR9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS05865 ^@ http://purl.uniprot.org/uniprot/D5EIF5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS13395 ^@ http://purl.uniprot.org/uniprot/D5EPX7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS10775 ^@ http://purl.uniprot.org/uniprot/D5EM29 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/583355:CAKA_RS00695 ^@ http://purl.uniprot.org/uniprot/D5EL74 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||In the N-terminal section; belongs to the FGAMS family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. http://togogenome.org/gene/583355:CAKA_RS05435 ^@ http://purl.uniprot.org/uniprot/D5EHU8 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/583355:CAKA_RS12895 ^@ http://purl.uniprot.org/uniprot/D5EPA1 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/583355:CAKA_RS15045 ^@ http://purl.uniprot.org/uniprot/D5EI00 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS11815 ^@ http://purl.uniprot.org/uniprot/D5ENB9 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/583355:CAKA_RS12710 ^@ http://purl.uniprot.org/uniprot/D5EP64 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS12250 ^@ http://purl.uniprot.org/uniprot/D5ENK5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS11695 ^@ http://purl.uniprot.org/uniprot/D5EMY2 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS01310 ^@ http://purl.uniprot.org/uniprot/D5ELX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/583355:CAKA_RS16315 ^@ http://purl.uniprot.org/uniprot/D5EQ04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/583355:CAKA_RS04785 ^@ http://purl.uniprot.org/uniprot/D5ER12 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/583355:CAKA_RS03840 ^@ http://purl.uniprot.org/uniprot/D5EQ44 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/583355:CAKA_RS13475 ^@ http://purl.uniprot.org/uniprot/D5EPZ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/583355:CAKA_RS12660 ^@ http://purl.uniprot.org/uniprot/D5EP54 ^@ Similarity ^@ Belongs to the glycosyltransferase 10 family. http://togogenome.org/gene/583355:CAKA_RS03820 ^@ http://purl.uniprot.org/uniprot/D5EQ40 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/583355:CAKA_RS02565 ^@ http://purl.uniprot.org/uniprot/D5ENP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS14320 ^@ http://purl.uniprot.org/uniprot/D5ER49 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/583355:CAKA_RS06720 ^@ http://purl.uniprot.org/uniprot/D5EIY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/583355:CAKA_RS00735 ^@ http://purl.uniprot.org/uniprot/D5EL82 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/583355:CAKA_RS03310 ^@ http://purl.uniprot.org/uniprot/D5EPH0 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/583355:CAKA_RS08725 ^@ http://purl.uniprot.org/uniprot/D5EK31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS14125 ^@ http://purl.uniprot.org/uniprot/D5EQP0 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/583355:CAKA_RS04120 ^@ http://purl.uniprot.org/uniprot/D5EQ99 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/583355:CAKA_RS15575 ^@ http://purl.uniprot.org/uniprot/D5EKI6 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/583355:CAKA_RS11865 ^@ http://purl.uniprot.org/uniprot/D5ENC9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS03530 ^@ http://purl.uniprot.org/uniprot/D5EPL3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/583355:CAKA_RS13470 ^@ http://purl.uniprot.org/uniprot/D5EPZ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/583355:CAKA_RS12435 ^@ http://purl.uniprot.org/uniprot/D5ENP3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/583355:CAKA_RS05185 ^@ http://purl.uniprot.org/uniprot/D5EHP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/583355:CAKA_RS12930 ^@ http://purl.uniprot.org/uniprot/D5EPA8 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/583355:CAKA_RS12810 ^@ http://purl.uniprot.org/uniprot/D5EP84 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/583355:CAKA_RS12915 ^@ http://purl.uniprot.org/uniprot/D5EPA5 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/583355:CAKA_RS12965 ^@ http://purl.uniprot.org/uniprot/D5EPB5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/583355:CAKA_RS13555 ^@ http://purl.uniprot.org/uniprot/D5EQ09 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/583355:CAKA_RS07085 ^@ http://purl.uniprot.org/uniprot/D5EJ56 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/583355:CAKA_RS12765 ^@ http://purl.uniprot.org/uniprot/D5EP75 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/583355:CAKA_RS11355 ^@ http://purl.uniprot.org/uniprot/D5EMR3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/583355:CAKA_RS02970 ^@ http://purl.uniprot.org/uniprot/D5ENY3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/583355:CAKA_RS06530 ^@ http://purl.uniprot.org/uniprot/D5EIU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/583355:CAKA_RS12545 ^@ http://purl.uniprot.org/uniprot/D5EP32 ^@ Cofactor|||Similarity ^@ Belongs to the monomeric-type IDH family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/583355:CAKA_RS10730 ^@ http://purl.uniprot.org/uniprot/D5EM20 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/583355:CAKA_RS13925 ^@ http://purl.uniprot.org/uniprot/D5EQJ9 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/583355:CAKA_RS16195 ^@ http://purl.uniprot.org/uniprot/D5EMB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/583355:CAKA_RS14725 ^@ http://purl.uniprot.org/uniprot/D5ERD0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/583355:CAKA_RS14095 ^@ http://purl.uniprot.org/uniprot/D5EQN4 ^@ Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family. http://togogenome.org/gene/583355:CAKA_RS10110 ^@ http://purl.uniprot.org/uniprot/D5ELB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/583355:CAKA_RS14225 ^@ http://purl.uniprot.org/uniprot/D5EQQ8 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/583355:CAKA_RS13250 ^@ http://purl.uniprot.org/uniprot/D5EPU9 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/583355:CAKA_RS02345 ^@ http://purl.uniprot.org/uniprot/D5EN76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/583355:CAKA_RS07825 ^@ http://purl.uniprot.org/uniprot/D5EJK1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/583355:CAKA_RS08890 ^@ http://purl.uniprot.org/uniprot/D5EK64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/583355:CAKA_RS12760 ^@ http://purl.uniprot.org/uniprot/D5EP74 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/583355:CAKA_RS14490 ^@ http://purl.uniprot.org/uniprot/D5ER83 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer.