http://togogenome.org/gene/634177:GLX_RS01895 ^@ http://purl.uniprot.org/uniprot/G2I3T4 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/634177:GLX_RS09480 ^@ http://purl.uniprot.org/uniprot/G2HZW4 ^@ Function|||Similarity ^@ Belongs to the PqqB family.|||May be involved in the transport of PQQ or its precursor to the periplasm. http://togogenome.org/gene/634177:GLX_RS13700 ^@ http://purl.uniprot.org/uniprot/G2I2T6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/634177:GLX_RS14210 ^@ http://purl.uniprot.org/uniprot/G2I3J4 ^@ Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||In the C-terminal section; belongs to the AcsB/BcsB family.|||In the N-terminal section; belongs to the glycosyltransferase 2 family.|||Membrane http://togogenome.org/gene/634177:GLX_RS04925 ^@ http://purl.uniprot.org/uniprot/G2I5F2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/634177:GLX_RS12670 ^@ http://purl.uniprot.org/uniprot/G2I1S4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS06080 ^@ http://purl.uniprot.org/uniprot/G2I628 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/634177:GLX_RS05520 ^@ http://purl.uniprot.org/uniprot/G2I5S1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/634177:GLX_RS10025 ^@ http://purl.uniprot.org/uniprot/G2I078 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS09560 ^@ http://purl.uniprot.org/uniprot/G2HZY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS02170 ^@ http://purl.uniprot.org/uniprot/G2I3Y7 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/634177:GLX_RS03975 ^@ http://purl.uniprot.org/uniprot/G2I4X6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/634177:GLX_RS05960 ^@ http://purl.uniprot.org/uniprot/G2I608 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS07060 ^@ http://purl.uniprot.org/uniprot/G2I6K9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/634177:GLX_RS13775 ^@ http://purl.uniprot.org/uniprot/G2I2V1 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/634177:GLX_RS13670 ^@ http://purl.uniprot.org/uniprot/G2I2T0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/634177:GLX_RS09290 ^@ http://purl.uniprot.org/uniprot/G2HZS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS12845 ^@ http://purl.uniprot.org/uniprot/G2I1V9 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/634177:GLX_RS07800 ^@ http://purl.uniprot.org/uniprot/G2I700 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M15D family.|||Binds 1 zinc ion per subunit.|||Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. http://togogenome.org/gene/634177:GLX_RS05320 ^@ http://purl.uniprot.org/uniprot/G2I5N1 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/634177:GLX_RS06410 ^@ http://purl.uniprot.org/uniprot/G2I690 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/634177:GLX_RS03130 ^@ http://purl.uniprot.org/uniprot/G2I4G2 ^@ Similarity ^@ Belongs to the bacterial PQQ dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS07290 ^@ http://purl.uniprot.org/uniprot/G2I6Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family. Hemolysin C subfamily.|||Membrane http://togogenome.org/gene/634177:GLX_RS04305 ^@ http://purl.uniprot.org/uniprot/G2I540 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS14000 ^@ http://purl.uniprot.org/uniprot/G2I3G0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/634177:GLX_RS01950 ^@ http://purl.uniprot.org/uniprot/G2I3U5 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/634177:GLX_RS04700 ^@ http://purl.uniprot.org/uniprot/G2I5A8 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/634177:GLX_RS12680 ^@ http://purl.uniprot.org/uniprot/G2I1S6 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/634177:GLX_RS02675 ^@ http://purl.uniprot.org/uniprot/G2I477 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/634177:GLX_RS15125 ^@ http://purl.uniprot.org/uniprot/G2I842 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Cell membrane|||Involved in arsenical resistance. Thought to form the channel of an arsenite pump.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/634177:GLX_RS05460 ^@ http://purl.uniprot.org/uniprot/G2I5Q9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/634177:GLX_RS12650 ^@ http://purl.uniprot.org/uniprot/G2I1S0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/634177:GLX_RS04845 ^@ http://purl.uniprot.org/uniprot/G2I5D6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/634177:GLX_RS05610 ^@ http://purl.uniprot.org/uniprot/G2I5T9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/634177:GLX_RS13475 ^@ http://purl.uniprot.org/uniprot/G2I2P1 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/634177:GLX_RS01375 ^@ http://purl.uniprot.org/uniprot/G2I379 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS12880 ^@ http://purl.uniprot.org/uniprot/G2I1W6 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. http://togogenome.org/gene/634177:GLX_RS12900 ^@ http://purl.uniprot.org/uniprot/G2I1X0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/634177:GLX_RS15455 ^@ http://purl.uniprot.org/uniprot/G2I8B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS00685 ^@ http://purl.uniprot.org/uniprot/G2I2D0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/634177:GLX_RS02625 ^@ http://purl.uniprot.org/uniprot/G2I254 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/634177:GLX_RS10510 ^@ http://purl.uniprot.org/uniprot/G2I0H3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS00050 ^@ http://purl.uniprot.org/uniprot/G2I1K0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/634177:GLX_RS16705 ^@ http://purl.uniprot.org/uniprot/G2I5Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0391 family.|||Cell membrane http://togogenome.org/gene/634177:GLX_RS00595 ^@ http://purl.uniprot.org/uniprot/G2I2B2 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS02975 ^@ http://purl.uniprot.org/uniprot/G2I4D1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer and homodimer. http://togogenome.org/gene/634177:GLX_RS03865 ^@ http://purl.uniprot.org/uniprot/G2I4V5 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/634177:GLX_RS05555 ^@ http://purl.uniprot.org/uniprot/G2I5S8 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/634177:GLX_RS13440 ^@ http://purl.uniprot.org/uniprot/G2I2N4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/634177:GLX_RS06350 ^@ http://purl.uniprot.org/uniprot/G2I677 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/634177:GLX_RS05545 ^@ http://purl.uniprot.org/uniprot/G2I5S6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/634177:GLX_RS05940 ^@ http://purl.uniprot.org/uniprot/G2I604 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell inner membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/634177:GLX_RS08935 ^@ http://purl.uniprot.org/uniprot/G2I7L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/634177:GLX_RS09110 ^@ http://purl.uniprot.org/uniprot/G2I7Q4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS06640 ^@ http://purl.uniprot.org/uniprot/G2I6D0 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/634177:GLX_RS04530 ^@ http://purl.uniprot.org/uniprot/G2I577 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/634177:GLX_RS09420 ^@ http://purl.uniprot.org/uniprot/G2HZV2 ^@ Function ^@ Multidrug efflux pump. http://togogenome.org/gene/634177:GLX_RS03240 ^@ http://purl.uniprot.org/uniprot/G2I4I3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/634177:GLX_RS11685 ^@ http://purl.uniprot.org/uniprot/G2I147 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/634177:GLX_RS05605 ^@ http://purl.uniprot.org/uniprot/G2I5T8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/634177:GLX_RS10780 ^@ http://purl.uniprot.org/uniprot/G2I0M6 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS08885 ^@ http://purl.uniprot.org/uniprot/G2I7K7 ^@ Similarity ^@ Belongs to the UPF0260 family. http://togogenome.org/gene/634177:GLX_RS13800 ^@ http://purl.uniprot.org/uniprot/G2I2V7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS04215 ^@ http://purl.uniprot.org/uniprot/G2I523 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/634177:GLX_RS04185 ^@ http://purl.uniprot.org/uniprot/G2I518 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/634177:GLX_RS09535 ^@ http://purl.uniprot.org/uniprot/G2HZX5 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS07065 ^@ http://purl.uniprot.org/uniprot/G2I6L0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/634177:GLX_RS13095 ^@ http://purl.uniprot.org/uniprot/G2I209 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/634177:GLX_RS06150 ^@ http://purl.uniprot.org/uniprot/G2I642 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS12450 ^@ http://purl.uniprot.org/uniprot/G2I1N1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS04565 ^@ http://purl.uniprot.org/uniprot/G2I584 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/634177:GLX_RS09820 ^@ http://purl.uniprot.org/uniprot/G2I039 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS07040 ^@ http://purl.uniprot.org/uniprot/G2I6K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/634177:GLX_RS03375 ^@ http://purl.uniprot.org/uniprot/G2I4L0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/634177:GLX_RS02030 ^@ http://purl.uniprot.org/uniprot/G2I3W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS03925 ^@ http://purl.uniprot.org/uniprot/G2I4W7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS09605 ^@ http://purl.uniprot.org/uniprot/G2HZY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/634177:GLX_RS17865 ^@ http://purl.uniprot.org/uniprot/G2I8S5 ^@ Similarity ^@ Belongs to the YoeB family. http://togogenome.org/gene/634177:GLX_RS15935 ^@ http://purl.uniprot.org/uniprot/G2I8L1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS01530 ^@ http://purl.uniprot.org/uniprot/G2I3A8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS10275 ^@ http://purl.uniprot.org/uniprot/G2I0C7 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. http://togogenome.org/gene/634177:GLX_RS00765 ^@ http://purl.uniprot.org/uniprot/G2I2E6 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/634177:GLX_RS07070 ^@ http://purl.uniprot.org/uniprot/G2I6L1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS09075 ^@ http://purl.uniprot.org/uniprot/G2I7P7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/634177:GLX_RS08400 ^@ http://purl.uniprot.org/uniprot/G2I7C0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/634177:GLX_RS13045 ^@ http://purl.uniprot.org/uniprot/G2I1Z9 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/634177:GLX_RS10240 ^@ http://purl.uniprot.org/uniprot/G2I0C0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/634177:GLX_RS05815 ^@ http://purl.uniprot.org/uniprot/G2I5Y0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/634177:GLX_RS13105 ^@ http://purl.uniprot.org/uniprot/G2I211 ^@ Cofactor|||Similarity ^@ Belongs to the class-II DAHP synthase family.|||Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions. http://togogenome.org/gene/634177:GLX_RS05030 ^@ http://purl.uniprot.org/uniprot/G2I5H3 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/634177:GLX_RS15275 ^@ http://purl.uniprot.org/uniprot/G2I875 ^@ Similarity ^@ Belongs to the OprB family. http://togogenome.org/gene/634177:GLX_RS01350 ^@ http://purl.uniprot.org/uniprot/G2I374 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/634177:GLX_RS05265 ^@ http://purl.uniprot.org/uniprot/G2I5M0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/634177:GLX_RS08825 ^@ http://purl.uniprot.org/uniprot/G2I7J5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK. http://togogenome.org/gene/634177:GLX_RS10155 ^@ http://purl.uniprot.org/uniprot/G2I0A3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/634177:GLX_RS05800 ^@ http://purl.uniprot.org/uniprot/G2I5X7 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/634177:GLX_RS12245 ^@ http://purl.uniprot.org/uniprot/G2I1G9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/634177:GLX_RS03470 ^@ http://purl.uniprot.org/uniprot/G2I4M7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/634177:GLX_RS15020 ^@ http://purl.uniprot.org/uniprot/G2I820 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/634177:GLX_RS11990 ^@ http://purl.uniprot.org/uniprot/G2I1B0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS14070 ^@ http://purl.uniprot.org/uniprot/G2I3H3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS10055 ^@ http://purl.uniprot.org/uniprot/G2I084 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/634177:GLX_RS03330 ^@ http://purl.uniprot.org/uniprot/G2I4K1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS10085 ^@ http://purl.uniprot.org/uniprot/G2I089 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS03090 ^@ http://purl.uniprot.org/uniprot/G2I4F4 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/634177:GLX_RS12800 ^@ http://purl.uniprot.org/uniprot/G2I1V0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS16400 ^@ http://purl.uniprot.org/uniprot/G2I8V6 ^@ Similarity ^@ Belongs to the RelE toxin family. http://togogenome.org/gene/634177:GLX_RS14050 ^@ http://purl.uniprot.org/uniprot/G2I3H0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/634177:GLX_RS05200 ^@ http://purl.uniprot.org/uniprot/G2I5K7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/634177:GLX_RS11230 ^@ http://purl.uniprot.org/uniprot/G2I0W4 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/634177:GLX_RS10350 ^@ http://purl.uniprot.org/uniprot/G2I0E2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/634177:GLX_RS06530 ^@ http://purl.uniprot.org/uniprot/G2I6A8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/634177:GLX_RS14085 ^@ http://purl.uniprot.org/uniprot/G2I3H6 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/634177:GLX_RS16395 ^@ http://purl.uniprot.org/uniprot/G2I8V5 ^@ Similarity ^@ Belongs to the RelB/DinJ antitoxin family. http://togogenome.org/gene/634177:GLX_RS13975 ^@ http://purl.uniprot.org/uniprot/G2I3F4 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/634177:GLX_RS00825 ^@ http://purl.uniprot.org/uniprot/G2I2F7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/634177:GLX_RS08865 ^@ http://purl.uniprot.org/uniprot/G2I7K3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS06215 ^@ http://purl.uniprot.org/uniprot/G2I655 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell inner membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/634177:GLX_RS01795 ^@ http://purl.uniprot.org/uniprot/G2I3R5 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/634177:GLX_RS00705 ^@ http://purl.uniprot.org/uniprot/G2I2D5 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/634177:GLX_RS14515 ^@ http://purl.uniprot.org/uniprot/G2I3Q3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS15950 ^@ http://purl.uniprot.org/uniprot/G2I8L4 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/634177:GLX_RS11530 ^@ http://purl.uniprot.org/uniprot/G2I122 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/634177:GLX_RS09680 ^@ http://purl.uniprot.org/uniprot/G2I6X3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/634177:GLX_RS11395 ^@ http://purl.uniprot.org/uniprot/G2I0Z7 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/634177:GLX_RS00760 ^@ http://purl.uniprot.org/uniprot/G2I2E5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS06515 ^@ http://purl.uniprot.org/uniprot/G2I6A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS03405 ^@ http://purl.uniprot.org/uniprot/G2I4L5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/634177:GLX_RS15665 ^@ http://purl.uniprot.org/uniprot/G2I8C5 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/634177:GLX_RS05780 ^@ http://purl.uniprot.org/uniprot/G2I5X3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/634177:GLX_RS12915 ^@ http://purl.uniprot.org/uniprot/G2I1X3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS09170 ^@ http://purl.uniprot.org/uniprot/G2I7R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS16610 ^@ http://purl.uniprot.org/uniprot/G2I772 ^@ Similarity ^@ Belongs to the virb1 family. http://togogenome.org/gene/634177:GLX_RS04510 ^@ http://purl.uniprot.org/uniprot/G2I573 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/634177:GLX_RS01520 ^@ http://purl.uniprot.org/uniprot/G2I3A6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/634177:GLX_RS01790 ^@ http://purl.uniprot.org/uniprot/G2I3R4 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/634177:GLX_RS13040 ^@ http://purl.uniprot.org/uniprot/G2I1Z8 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/634177:GLX_RS10320 ^@ http://purl.uniprot.org/uniprot/G2I0D6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).|||Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3). http://togogenome.org/gene/634177:GLX_RS12390 ^@ http://purl.uniprot.org/uniprot/G2I1L9 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS00490 ^@ http://purl.uniprot.org/uniprot/G2I291 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS01185 ^@ http://purl.uniprot.org/uniprot/G2I6X3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/634177:GLX_RS12465 ^@ http://purl.uniprot.org/uniprot/G2I1N4 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/634177:GLX_RS10775 ^@ http://purl.uniprot.org/uniprot/G2I0M5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/634177:GLX_RS03210 ^@ http://purl.uniprot.org/uniprot/G2I4H7 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/634177:GLX_RS11415 ^@ http://purl.uniprot.org/uniprot/G2I101 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS01395 ^@ http://purl.uniprot.org/uniprot/G2I383 ^@ Similarity ^@ Belongs to the OprB family. http://togogenome.org/gene/634177:GLX_RS13255 ^@ http://purl.uniprot.org/uniprot/G2I2J7 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/634177:GLX_RS02285 ^@ http://purl.uniprot.org/uniprot/G2I408 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS13080 ^@ http://purl.uniprot.org/uniprot/G2I206 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS07660 ^@ http://purl.uniprot.org/uniprot/G2I6X3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/634177:GLX_RS03550 ^@ http://purl.uniprot.org/uniprot/G2I4P2 ^@ Similarity ^@ Belongs to the UPF0053 family. Hemolysin C subfamily. http://togogenome.org/gene/634177:GLX_RS04335 ^@ http://purl.uniprot.org/uniprot/G2I546 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/634177:GLX_RS10970 ^@ http://purl.uniprot.org/uniprot/G2I0R2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/634177:GLX_RS15505 ^@ http://purl.uniprot.org/uniprot/G2I8C4 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/634177:GLX_RS04255 ^@ http://purl.uniprot.org/uniprot/G2I530 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/634177:GLX_RS00140 ^@ http://purl.uniprot.org/uniprot/G2I225 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/634177:GLX_RS13140 ^@ http://purl.uniprot.org/uniprot/G2I218 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/634177:GLX_RS00090 ^@ http://purl.uniprot.org/uniprot/G2I1K9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS01450 ^@ http://purl.uniprot.org/uniprot/G2I393 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS08540 ^@ http://purl.uniprot.org/uniprot/G2I7F0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/634177:GLX_RS05035 ^@ http://purl.uniprot.org/uniprot/G2I5H4 ^@ Function ^@ Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY. http://togogenome.org/gene/634177:GLX_RS05305 ^@ http://purl.uniprot.org/uniprot/G2I5M8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/634177:GLX_RS03900 ^@ http://purl.uniprot.org/uniprot/G2I4W2 ^@ Similarity ^@ Belongs to the transglycosylase Slt family.|||Belongs to the virb1 family. http://togogenome.org/gene/634177:GLX_RS05295 ^@ http://purl.uniprot.org/uniprot/G2I5M6 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/634177:GLX_RS03585 ^@ http://purl.uniprot.org/uniprot/G2I4P9 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/634177:GLX_RS03980 ^@ http://purl.uniprot.org/uniprot/G2I4X7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PpiC/parvulin rotamase family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS07850 ^@ http://purl.uniprot.org/uniprot/G2I712 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/634177:GLX_RS15365 ^@ http://purl.uniprot.org/uniprot/G2I893 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS13840 ^@ http://purl.uniprot.org/uniprot/G2I2W5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/634177:GLX_RS05470 ^@ http://purl.uniprot.org/uniprot/G2I5R1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/634177:GLX_RS04625 ^@ http://purl.uniprot.org/uniprot/G2I594 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/634177:GLX_RS10040 ^@ http://purl.uniprot.org/uniprot/G2I081 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/634177:GLX_RS12940 ^@ http://purl.uniprot.org/uniprot/G2I1X7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/634177:GLX_RS12385 ^@ http://purl.uniprot.org/uniprot/G2I1L8 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/634177:GLX_RS17480 ^@ http://purl.uniprot.org/uniprot/G2I1D2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS12820 ^@ http://purl.uniprot.org/uniprot/G2I1V4 ^@ Function|||Similarity|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ. http://togogenome.org/gene/634177:GLX_RS05580 ^@ http://purl.uniprot.org/uniprot/G2I5T3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/634177:GLX_RS07140 ^@ http://purl.uniprot.org/uniprot/G2I6M4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the trans-sulfuration enzymes family. MetZ subfamily.|||Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.|||Homotetramer. http://togogenome.org/gene/634177:GLX_RS01340 ^@ http://purl.uniprot.org/uniprot/G2I372 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS12070 ^@ http://purl.uniprot.org/uniprot/G2I1D0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/634177:GLX_RS05180 ^@ http://purl.uniprot.org/uniprot/G2I5K3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS02730 ^@ http://purl.uniprot.org/uniprot/G2I487 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/634177:GLX_RS01090 ^@ http://purl.uniprot.org/uniprot/G2I321 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS07180 ^@ http://purl.uniprot.org/uniprot/G2I6N2 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit. http://togogenome.org/gene/634177:GLX_RS07395 ^@ http://purl.uniprot.org/uniprot/G2I6S5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/634177:GLX_RS14570 ^@ http://purl.uniprot.org/uniprot/G2I7S7 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/634177:GLX_RS09930 ^@ http://purl.uniprot.org/uniprot/G2I060 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. YhhS family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS09565 ^@ http://purl.uniprot.org/uniprot/G2HZY1 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/634177:GLX_RS03960 ^@ http://purl.uniprot.org/uniprot/G2I4X3 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/634177:GLX_RS05315 ^@ http://purl.uniprot.org/uniprot/G2I5N0 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/634177:GLX_RS00240 ^@ http://purl.uniprot.org/uniprot/G2I245 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS03030 ^@ http://purl.uniprot.org/uniprot/G2I4E2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/634177:GLX_RS09300 ^@ http://purl.uniprot.org/uniprot/G2HZT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/634177:GLX_RS15920 ^@ http://purl.uniprot.org/uniprot/G2I8K8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell inner membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/634177:GLX_RS01115 ^@ http://purl.uniprot.org/uniprot/G2I326 ^@ Function|||Subcellular Location Annotation ^@ Could be a virulence factor.|||Secreted http://togogenome.org/gene/634177:GLX_RS13120 ^@ http://purl.uniprot.org/uniprot/G2I214 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/634177:GLX_RS04840 ^@ http://purl.uniprot.org/uniprot/G2I5D5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/634177:GLX_RS00940 ^@ http://purl.uniprot.org/uniprot/G2I2Z0 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/634177:GLX_RS05040 ^@ http://purl.uniprot.org/uniprot/G2I5H5 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/634177:GLX_RS00195 ^@ http://purl.uniprot.org/uniprot/G2I236 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/634177:GLX_RS00515 ^@ http://purl.uniprot.org/uniprot/G2I296 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/634177:GLX_RS12300 ^@ http://purl.uniprot.org/uniprot/G2I1I0 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/634177:GLX_RS13765 ^@ http://purl.uniprot.org/uniprot/G2I2U9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/634177:GLX_RS10140 ^@ http://purl.uniprot.org/uniprot/G2I0A0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/634177:GLX_RS05845 ^@ http://purl.uniprot.org/uniprot/G2I5Y6 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/634177:GLX_RS16260 ^@ http://purl.uniprot.org/uniprot/G2I8S8 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/634177:GLX_RS13935 ^@ http://purl.uniprot.org/uniprot/G2I2Y4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/634177:GLX_RS01305 ^@ http://purl.uniprot.org/uniprot/G2I365 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS13530 ^@ http://purl.uniprot.org/uniprot/G2I2Q1 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/634177:GLX_RS00625 ^@ http://purl.uniprot.org/uniprot/G2I2B9 ^@ Caution|||Function|||Similarity ^@ Belongs to the globin family.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS07765 ^@ http://purl.uniprot.org/uniprot/G2I6Z3 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/634177:GLX_RS03105 ^@ http://purl.uniprot.org/uniprot/G2I4F7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/634177:GLX_RS00860 ^@ http://purl.uniprot.org/uniprot/G2I2G4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS04290 ^@ http://purl.uniprot.org/uniprot/G2I537 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS06100 ^@ http://purl.uniprot.org/uniprot/G2I632 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/634177:GLX_RS00010 ^@ http://purl.uniprot.org/uniprot/G2I1J2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/634177:GLX_RS06220 ^@ http://purl.uniprot.org/uniprot/G2I656 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS13685 ^@ http://purl.uniprot.org/uniprot/G2I2T3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/634177:GLX_RS07010 ^@ http://purl.uniprot.org/uniprot/G2I6J9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS13850 ^@ http://purl.uniprot.org/uniprot/G2I2W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS09510 ^@ http://purl.uniprot.org/uniprot/G2HZX0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/634177:GLX_RS04000 ^@ http://purl.uniprot.org/uniprot/G2I4Y1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS10050 ^@ http://purl.uniprot.org/uniprot/G2I083 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS14040 ^@ http://purl.uniprot.org/uniprot/G2I3G8 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/634177:GLX_RS07475 ^@ http://purl.uniprot.org/uniprot/G2I6T8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS03125 ^@ http://purl.uniprot.org/uniprot/G2I4G1 ^@ Cofactor ^@ Binds 3 heme c groups covalently per subunit. http://togogenome.org/gene/634177:GLX_RS10295 ^@ http://purl.uniprot.org/uniprot/G2I0D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/634177:GLX_RS15655 ^@ http://purl.uniprot.org/uniprot/G2I8F9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS06790 ^@ http://purl.uniprot.org/uniprot/G2I6G0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/634177:GLX_RS05190 ^@ http://purl.uniprot.org/uniprot/G2I5K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PpiC/parvulin rotamase family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS03615 ^@ http://purl.uniprot.org/uniprot/G2I4Q5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/634177:GLX_RS09840 ^@ http://purl.uniprot.org/uniprot/G2I043 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/634177:GLX_RS13805 ^@ http://purl.uniprot.org/uniprot/G2I2V8 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/634177:GLX_RS11280 ^@ http://purl.uniprot.org/uniprot/G2I0X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/634177:GLX_RS11515 ^@ http://purl.uniprot.org/uniprot/G2I119 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/634177:GLX_RS05705 ^@ http://purl.uniprot.org/uniprot/G2I5V8 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS10485 ^@ http://purl.uniprot.org/uniprot/G2I0G8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/634177:GLX_RS06785 ^@ http://purl.uniprot.org/uniprot/G2I6F9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/634177:GLX_RS03235 ^@ http://purl.uniprot.org/uniprot/G2I4I2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/634177:GLX_RS02700 ^@ http://purl.uniprot.org/uniprot/G2I482 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/634177:GLX_RS05750 ^@ http://purl.uniprot.org/uniprot/G2I5W7 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/634177:GLX_RS13325 ^@ http://purl.uniprot.org/uniprot/G2I2L1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/634177:GLX_RS05570 ^@ http://purl.uniprot.org/uniprot/G2I5T1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/634177:GLX_RS04500 ^@ http://purl.uniprot.org/uniprot/G2I571 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/634177:GLX_RS10605 ^@ http://purl.uniprot.org/uniprot/G2I0J2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/634177:GLX_RS14115 ^@ http://purl.uniprot.org/uniprot/G2I3I2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial glucokinase family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS10940 ^@ http://purl.uniprot.org/uniprot/G2I0Q7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons.|||Oligomer of 12 subunits arranged in the form of two hexameric ring. http://togogenome.org/gene/634177:GLX_RS13090 ^@ http://purl.uniprot.org/uniprot/G2I208 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/634177:GLX_RS07365 ^@ http://purl.uniprot.org/uniprot/G2I6R9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/634177:GLX_RS13925 ^@ http://purl.uniprot.org/uniprot/G2I2Y2 ^@ Function|||Similarity ^@ Belongs to the polysaccharide deacetylase family.|||Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts. http://togogenome.org/gene/634177:GLX_RS15450 ^@ http://purl.uniprot.org/uniprot/G2I8B2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/634177:GLX_RS07480 ^@ http://purl.uniprot.org/uniprot/G2I6T9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS03505 ^@ http://purl.uniprot.org/uniprot/G2I4N4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS00745 ^@ http://purl.uniprot.org/uniprot/G2I2E2 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/634177:GLX_RS13310 ^@ http://purl.uniprot.org/uniprot/G2I2K8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/634177:GLX_RS05585 ^@ http://purl.uniprot.org/uniprot/G2I5T4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/634177:GLX_RS03985 ^@ http://purl.uniprot.org/uniprot/G2I4X8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS01145 ^@ http://purl.uniprot.org/uniprot/G2I332 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/634177:GLX_RS01820 ^@ http://purl.uniprot.org/uniprot/G2I3S0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/634177:GLX_RS13455 ^@ http://purl.uniprot.org/uniprot/G2I2N7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/634177:GLX_RS05915 ^@ http://purl.uniprot.org/uniprot/G2I5Z9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/634177:GLX_RS03705 ^@ http://purl.uniprot.org/uniprot/G2I4S3 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/634177:GLX_RS05390 ^@ http://purl.uniprot.org/uniprot/G2I5P5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/634177:GLX_RS05505 ^@ http://purl.uniprot.org/uniprot/G2I5R8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/634177:GLX_RS10580 ^@ http://purl.uniprot.org/uniprot/G2I0I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/634177:GLX_RS00145 ^@ http://purl.uniprot.org/uniprot/G2I226 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer. http://togogenome.org/gene/634177:GLX_RS12925 ^@ http://purl.uniprot.org/uniprot/G2I1X4 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. http://togogenome.org/gene/634177:GLX_RS00830 ^@ http://purl.uniprot.org/uniprot/G2I2F8 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/634177:GLX_RS08605 ^@ http://purl.uniprot.org/uniprot/G2I7G2 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/634177:GLX_RS00820 ^@ http://purl.uniprot.org/uniprot/G2I2F6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS05535 ^@ http://purl.uniprot.org/uniprot/G2I5S4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/634177:GLX_RS02920 ^@ http://purl.uniprot.org/uniprot/G2I4C1 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/634177:GLX_RS04605 ^@ http://purl.uniprot.org/uniprot/G2I592 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell inner membrane|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/634177:GLX_RS10805 ^@ http://purl.uniprot.org/uniprot/G2I0N1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/634177:GLX_RS00845 ^@ http://purl.uniprot.org/uniprot/G2I2G1 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/634177:GLX_RS04150 ^@ http://purl.uniprot.org/uniprot/G2I511 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/634177:GLX_RS04310 ^@ http://purl.uniprot.org/uniprot/G2I541 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS14320 ^@ http://purl.uniprot.org/uniprot/G2I3L6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/634177:GLX_RS03995 ^@ http://purl.uniprot.org/uniprot/G2I4Y0 ^@ Activity Regulation|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer. http://togogenome.org/gene/634177:GLX_RS12895 ^@ http://purl.uniprot.org/uniprot/G2I1W9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/634177:GLX_RS02600 ^@ http://purl.uniprot.org/uniprot/G2I464 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS05880 ^@ http://purl.uniprot.org/uniprot/G2I5Z3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane http://togogenome.org/gene/634177:GLX_RS04670 ^@ http://purl.uniprot.org/uniprot/G2I5A2 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/634177:GLX_RS04160 ^@ http://purl.uniprot.org/uniprot/G2I513 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/634177:GLX_RS08950 ^@ http://purl.uniprot.org/uniprot/G2I254 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/634177:GLX_RS07215 ^@ http://purl.uniprot.org/uniprot/G2I6N9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/634177:GLX_RS06740 ^@ http://purl.uniprot.org/uniprot/G2I6F0 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS00465 ^@ http://purl.uniprot.org/uniprot/G2I286 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M81 family.|||Binds 1 zinc ion per subunit.|||Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC). http://togogenome.org/gene/634177:GLX_RS01075 ^@ http://purl.uniprot.org/uniprot/G2I318 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS05935 ^@ http://purl.uniprot.org/uniprot/G2I603 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/634177:GLX_RS04695 ^@ http://purl.uniprot.org/uniprot/G2I5A7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/634177:GLX_RS15785 ^@ http://purl.uniprot.org/uniprot/G2I8I3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbI/VirB10 family.|||Membrane http://togogenome.org/gene/634177:GLX_RS12850 ^@ http://purl.uniprot.org/uniprot/G2I1W0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/634177:GLX_RS05090 ^@ http://purl.uniprot.org/uniprot/G2I5I5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Binds 2 Zn(2+) ions per subunit.|||Monomer.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/634177:GLX_RS14520 ^@ http://purl.uniprot.org/uniprot/G2I3Q4 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/634177:GLX_RS05575 ^@ http://purl.uniprot.org/uniprot/G2I5T2 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/634177:GLX_RS01210 ^@ http://purl.uniprot.org/uniprot/G2I346 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS16370 ^@ http://purl.uniprot.org/uniprot/G2I8U9 ^@ Similarity ^@ Belongs to the MobA/MobL family. http://togogenome.org/gene/634177:GLX_RS04120 ^@ http://purl.uniprot.org/uniprot/G2I505 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/634177:GLX_RS15875 ^@ http://purl.uniprot.org/uniprot/G2I8K0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter. http://togogenome.org/gene/634177:GLX_RS16155 ^@ http://purl.uniprot.org/uniprot/G2I8Q7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS11475 ^@ http://purl.uniprot.org/uniprot/G2I111 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell inner membrane http://togogenome.org/gene/634177:GLX_RS00315 ^@ http://purl.uniprot.org/uniprot/G2I254 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/634177:GLX_RS09105 ^@ http://purl.uniprot.org/uniprot/G2I7Q3 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/634177:GLX_RS04300 ^@ http://purl.uniprot.org/uniprot/G2I539 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS06795 ^@ http://purl.uniprot.org/uniprot/G2I6G1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/634177:GLX_RS11740 ^@ http://purl.uniprot.org/uniprot/G2I158 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbI/VirB10 family.|||Membrane http://togogenome.org/gene/634177:GLX_RS07085 ^@ http://purl.uniprot.org/uniprot/G2I6L4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/634177:GLX_RS04140 ^@ http://purl.uniprot.org/uniprot/G2I509 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS03500 ^@ http://purl.uniprot.org/uniprot/G2I4N3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/634177:GLX_RS14295 ^@ http://purl.uniprot.org/uniprot/G2I3L1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS04340 ^@ http://purl.uniprot.org/uniprot/G2I547 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/634177:GLX_RS05600 ^@ http://purl.uniprot.org/uniprot/G2I5T7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/634177:GLX_RS10225 ^@ http://purl.uniprot.org/uniprot/G2I0B7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein bS18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS00005 ^@ http://purl.uniprot.org/uniprot/G2I1J1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/634177:GLX_RS12685 ^@ http://purl.uniprot.org/uniprot/G2I1S7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/634177:GLX_RS01460 ^@ http://purl.uniprot.org/uniprot/G2I395 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/634177:GLX_RS03015 ^@ http://purl.uniprot.org/uniprot/G2I4D9 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/634177:GLX_RS03905 ^@ http://purl.uniprot.org/uniprot/G2I4W3 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). http://togogenome.org/gene/634177:GLX_RS14010 ^@ http://purl.uniprot.org/uniprot/G2I3G2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/634177:GLX_RS04495 ^@ http://purl.uniprot.org/uniprot/G2I570 ^@ Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||In the C-terminal section; belongs to the AcsB/BcsB family.|||In the N-terminal section; belongs to the glycosyltransferase 2 family.|||Membrane http://togogenome.org/gene/634177:GLX_RS02000 ^@ http://purl.uniprot.org/uniprot/G2I3V5 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/634177:GLX_RS03430 ^@ http://purl.uniprot.org/uniprot/G2I4L9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/634177:GLX_RS00130 ^@ http://purl.uniprot.org/uniprot/G2I223 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS14410 ^@ http://purl.uniprot.org/uniprot/G2I3N4 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/634177:GLX_RS05475 ^@ http://purl.uniprot.org/uniprot/G2I5R2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/634177:GLX_RS05810 ^@ http://purl.uniprot.org/uniprot/G2I5X9 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/634177:GLX_RS16145 ^@ http://purl.uniprot.org/uniprot/G2I8L4 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/634177:GLX_RS10575 ^@ http://purl.uniprot.org/uniprot/G2I0I6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS10365 ^@ http://purl.uniprot.org/uniprot/G2I0E5 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/634177:GLX_RS14430 ^@ http://purl.uniprot.org/uniprot/G2I3N8 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/634177:GLX_RS09140 ^@ http://purl.uniprot.org/uniprot/G2I7R0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS08510 ^@ http://purl.uniprot.org/uniprot/G2I7E4 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/634177:GLX_RS13525 ^@ http://purl.uniprot.org/uniprot/G2I2Q0 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/634177:GLX_RS13740 ^@ http://purl.uniprot.org/uniprot/G2I2U4 ^@ Cofactor|||Similarity ^@ Belongs to the bacterial PQQ dehydrogenase family.|||Binds 1 Ca(2+) ion per subunit.|||Binds 1 PQQ group per subunit.|||Binds 1 heme c group per subunit. http://togogenome.org/gene/634177:GLX_RS00015 ^@ http://purl.uniprot.org/uniprot/G2I1J3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/634177:GLX_RS00330 ^@ http://purl.uniprot.org/uniprot/G2I254 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/634177:GLX_RS00160 ^@ http://purl.uniprot.org/uniprot/G2I229 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/634177:GLX_RS14095 ^@ http://purl.uniprot.org/uniprot/G2I3H8 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/634177:GLX_RS13730 ^@ http://purl.uniprot.org/uniprot/G2I2U2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. http://togogenome.org/gene/634177:GLX_RS00950 ^@ http://purl.uniprot.org/uniprot/G2I2Z2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS13340 ^@ http://purl.uniprot.org/uniprot/G2I2L4 ^@ Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/634177:GLX_RS01890 ^@ http://purl.uniprot.org/uniprot/G2I3T3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS03640 ^@ http://purl.uniprot.org/uniprot/G2I4R0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/634177:GLX_RS07405 ^@ http://purl.uniprot.org/uniprot/G2I6S7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/634177:GLX_RS07440 ^@ http://purl.uniprot.org/uniprot/G2I6T2 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/634177:GLX_RS13355 ^@ http://purl.uniprot.org/uniprot/G2I2L7 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/634177:GLX_RS00100 ^@ http://purl.uniprot.org/uniprot/G2I1L1 ^@ Function|||Subunit ^@ DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease. http://togogenome.org/gene/634177:GLX_RS08430 ^@ http://purl.uniprot.org/uniprot/G2I7C6 ^@ Similarity ^@ Belongs to the class A bacterial acid phosphatase family. http://togogenome.org/gene/634177:GLX_RS07030 ^@ http://purl.uniprot.org/uniprot/G2I6K3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/634177:GLX_RS04220 ^@ http://purl.uniprot.org/uniprot/G2I524 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS12645 ^@ http://purl.uniprot.org/uniprot/G2I1R9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/634177:GLX_RS08480 ^@ http://purl.uniprot.org/uniprot/G2I7D6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS07385 ^@ http://purl.uniprot.org/uniprot/G2I6S3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/634177:GLX_RS13410 ^@ http://purl.uniprot.org/uniprot/G2I2M8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS05150 ^@ http://purl.uniprot.org/uniprot/G2I5J7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/634177:GLX_RS13300 ^@ http://purl.uniprot.org/uniprot/G2I2K6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/634177:GLX_RS13435 ^@ http://purl.uniprot.org/uniprot/G2I2N3 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/634177:GLX_RS13135 ^@ http://purl.uniprot.org/uniprot/G2I217 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/634177:GLX_RS01550 ^@ http://purl.uniprot.org/uniprot/G2I3B2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/634177:GLX_RS02850 ^@ http://purl.uniprot.org/uniprot/G2I4A7 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS15495 ^@ http://purl.uniprot.org/uniprot/G2I8C1 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. http://togogenome.org/gene/634177:GLX_RS08575 ^@ http://purl.uniprot.org/uniprot/G2I7F7 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/634177:GLX_RS04905 ^@ http://purl.uniprot.org/uniprot/G2I5E8 ^@ Similarity ^@ Belongs to the pseudomonas-type ThrB family. http://togogenome.org/gene/634177:GLX_RS03815 ^@ http://purl.uniprot.org/uniprot/G2I4U5 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/634177:GLX_RS04740 ^@ http://purl.uniprot.org/uniprot/G2I5B6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS09400 ^@ http://purl.uniprot.org/uniprot/G2HZU9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS06430 ^@ http://purl.uniprot.org/uniprot/G2I6X3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/634177:GLX_RS12490 ^@ http://purl.uniprot.org/uniprot/G2I1N9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS04155 ^@ http://purl.uniprot.org/uniprot/G2I512 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS06990 ^@ http://purl.uniprot.org/uniprot/G2I6J5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS14075 ^@ http://purl.uniprot.org/uniprot/G2I3H4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS09590 ^@ http://purl.uniprot.org/uniprot/G2HZY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS13215 ^@ http://purl.uniprot.org/uniprot/G2I2I9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS03520 ^@ http://purl.uniprot.org/uniprot/G2I4N7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS11260 ^@ http://purl.uniprot.org/uniprot/G2I0X1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/634177:GLX_RS03465 ^@ http://purl.uniprot.org/uniprot/G2I4M6 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/634177:GLX_RS06885 ^@ http://purl.uniprot.org/uniprot/G2I6H6 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/634177:GLX_RS04640 ^@ http://purl.uniprot.org/uniprot/G2I597 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/634177:GLX_RS03825 ^@ http://purl.uniprot.org/uniprot/G2I4U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS04210 ^@ http://purl.uniprot.org/uniprot/G2I522 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/634177:GLX_RS10030 ^@ http://purl.uniprot.org/uniprot/G2I079 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/634177:GLX_RS06505 ^@ http://purl.uniprot.org/uniprot/G2I6A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS04295 ^@ http://purl.uniprot.org/uniprot/G2I538 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell inner membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS10925 ^@ http://purl.uniprot.org/uniprot/G2I0Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/634177:GLX_RS02660 ^@ http://purl.uniprot.org/uniprot/G2I474 ^@ Similarity ^@ Belongs to the RNase T2 family. http://togogenome.org/gene/634177:GLX_RS04365 ^@ http://purl.uniprot.org/uniprot/G2I552 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS05230 ^@ http://purl.uniprot.org/uniprot/G2I5L3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/634177:GLX_RS00480 ^@ http://purl.uniprot.org/uniprot/G2I289 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/634177:GLX_RS03445 ^@ http://purl.uniprot.org/uniprot/G2I4M2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/634177:GLX_RS08860 ^@ http://purl.uniprot.org/uniprot/G2I7K2 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/634177:GLX_RS05495 ^@ http://purl.uniprot.org/uniprot/G2I5R6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/634177:GLX_RS12970 ^@ http://purl.uniprot.org/uniprot/G2I1Y2 ^@ Function|||Subcellular Location Annotation ^@ Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS10520 ^@ http://purl.uniprot.org/uniprot/G2I0H5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/634177:GLX_RS12190 ^@ http://purl.uniprot.org/uniprot/G2I1F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CitM (TC 2.A.11) transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS00660 ^@ http://purl.uniprot.org/uniprot/G2I2C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS00425 ^@ http://purl.uniprot.org/uniprot/G2I278 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M81 family.|||Binds 1 zinc ion per subunit.|||Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC). http://togogenome.org/gene/634177:GLX_RS05625 ^@ http://purl.uniprot.org/uniprot/G2I5U2 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/634177:GLX_RS14020 ^@ http://purl.uniprot.org/uniprot/G2I3G4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell inner membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/634177:GLX_RS01495 ^@ http://purl.uniprot.org/uniprot/G2I3A2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/634177:GLX_RS09530 ^@ http://purl.uniprot.org/uniprot/G2HZX4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS05245 ^@ http://purl.uniprot.org/uniprot/G2I5L6 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS14490 ^@ http://purl.uniprot.org/uniprot/G2I3P8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/634177:GLX_RS03625 ^@ http://purl.uniprot.org/uniprot/G2I4Q7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaE family.|||Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/634177:GLX_RS03780 ^@ http://purl.uniprot.org/uniprot/G2I4T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS10845 ^@ http://purl.uniprot.org/uniprot/G2I0N8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/634177:GLX_RS09390 ^@ http://purl.uniprot.org/uniprot/G2HZU7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HemJ family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/634177:GLX_RS05720 ^@ http://purl.uniprot.org/uniprot/G2I5W0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/634177:GLX_RS09455 ^@ http://purl.uniprot.org/uniprot/G2HZV9 ^@ Similarity ^@ Belongs to the OmpW/AlkL family. http://togogenome.org/gene/634177:GLX_RS04835 ^@ http://purl.uniprot.org/uniprot/G2I5D4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/634177:GLX_RS05620 ^@ http://purl.uniprot.org/uniprot/G2I5U1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/634177:GLX_RS12610 ^@ http://purl.uniprot.org/uniprot/G2I1R3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/634177:GLX_RS12375 ^@ http://purl.uniprot.org/uniprot/G2I1L6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell inner membrane|||Membrane|||Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter. http://togogenome.org/gene/634177:GLX_RS05175 ^@ http://purl.uniprot.org/uniprot/G2I5K2 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS14325 ^@ http://purl.uniprot.org/uniprot/G2I3L7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/634177:GLX_RS15775 ^@ http://purl.uniprot.org/uniprot/G2I8I1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS01870 ^@ http://purl.uniprot.org/uniprot/G2I3S9 ^@ Caution|||Cofactor|||Similarity ^@ Belongs to the WrbA family.|||Binds 1 FMN per monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS13600 ^@ http://purl.uniprot.org/uniprot/G2I2R6 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/634177:GLX_RS10000 ^@ http://purl.uniprot.org/uniprot/G2I073 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/634177:GLX_RS04110 ^@ http://purl.uniprot.org/uniprot/G2I503 ^@ Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family. http://togogenome.org/gene/634177:GLX_RS12230 ^@ http://purl.uniprot.org/uniprot/G2I1G6 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/634177:GLX_RS07410 ^@ http://purl.uniprot.org/uniprot/G2I6S8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/634177:GLX_RS17470 ^@ http://purl.uniprot.org/uniprot/G2I1B9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS13715 ^@ http://purl.uniprot.org/uniprot/G2I2T9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS08875 ^@ http://purl.uniprot.org/uniprot/G2I7K5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS06680 ^@ http://purl.uniprot.org/uniprot/G2I6D8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS02745 ^@ http://purl.uniprot.org/uniprot/G2I490 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS06635 ^@ http://purl.uniprot.org/uniprot/G2I6C9 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/634177:GLX_RS05005 ^@ http://purl.uniprot.org/uniprot/G2I5G8 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/634177:GLX_RS00035 ^@ http://purl.uniprot.org/uniprot/G2I1J7 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/634177:GLX_RS15905 ^@ http://purl.uniprot.org/uniprot/G2I8K6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS01070 ^@ http://purl.uniprot.org/uniprot/G2I317 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS05490 ^@ http://purl.uniprot.org/uniprot/G2I5R5 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/634177:GLX_RS01220 ^@ http://purl.uniprot.org/uniprot/G2I348 ^@ Function|||Similarity ^@ Belongs to the SsuD family.|||Catalyzes the desulfonation of aliphatic sulfonates. http://togogenome.org/gene/634177:GLX_RS13665 ^@ http://purl.uniprot.org/uniprot/G2I2S9 ^@ Cofactor ^@ Binds 1 heme c group covalently per subunit. http://togogenome.org/gene/634177:GLX_RS11645 ^@ http://purl.uniprot.org/uniprot/G2I139 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/634177:GLX_RS16090 ^@ http://purl.uniprot.org/uniprot/G2I8P3 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/634177:GLX_RS13165 ^@ http://purl.uniprot.org/uniprot/G2I2I0 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/634177:GLX_RS12630 ^@ http://purl.uniprot.org/uniprot/G2I1R7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IlvD/Edd family.|||Binds 1 [4Fe-4S] cluster.|||Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate. http://togogenome.org/gene/634177:GLX_RS16220 ^@ http://purl.uniprot.org/uniprot/G2I8S0 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/634177:GLX_RS06490 ^@ http://purl.uniprot.org/uniprot/G2I6A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS12980 ^@ http://purl.uniprot.org/uniprot/G2I1Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AcsC/BcsC family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS05485 ^@ http://purl.uniprot.org/uniprot/G2I5R4 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/634177:GLX_RS04755 ^@ http://purl.uniprot.org/uniprot/G2I5B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS00755 ^@ http://purl.uniprot.org/uniprot/G2I2E4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/634177:GLX_RS15660 ^@ http://purl.uniprot.org/uniprot/G2I8G0 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/634177:GLX_RS01005 ^@ http://purl.uniprot.org/uniprot/G2I303 ^@ Similarity ^@ Belongs to the sodium:galactoside symporter (TC 2.A.2) family. http://togogenome.org/gene/634177:GLX_RS07090 ^@ http://purl.uniprot.org/uniprot/G2I6L5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS13175 ^@ http://purl.uniprot.org/uniprot/G2I2I2 ^@ Function|||Similarity ^@ Belongs to the TenA family.|||Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. http://togogenome.org/gene/634177:GLX_RS09525 ^@ http://purl.uniprot.org/uniprot/G2HZX3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/634177:GLX_RS10655 ^@ http://purl.uniprot.org/uniprot/G2I0K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS04585 ^@ http://purl.uniprot.org/uniprot/G2I588 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/634177:GLX_RS16375 ^@ http://purl.uniprot.org/uniprot/G2I8V1 ^@ Similarity ^@ Belongs to the RelE toxin family. http://togogenome.org/gene/634177:GLX_RS00080 ^@ http://purl.uniprot.org/uniprot/G2I1K7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS07150 ^@ http://purl.uniprot.org/uniprot/G2I6M6 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/634177:GLX_RS01445 ^@ http://purl.uniprot.org/uniprot/G2I392 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS01540 ^@ http://purl.uniprot.org/uniprot/G2I3B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS12510 ^@ http://purl.uniprot.org/uniprot/G2I1P3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS03080 ^@ http://purl.uniprot.org/uniprot/G2I4F2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS05440 ^@ http://purl.uniprot.org/uniprot/G2I5Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/634177:GLX_RS07325 ^@ http://purl.uniprot.org/uniprot/G2I6R1 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/634177:GLX_RS01980 ^@ http://purl.uniprot.org/uniprot/G2I3V1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/634177:GLX_RS10445 ^@ http://purl.uniprot.org/uniprot/G2I0G1 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/634177:GLX_RS13315 ^@ http://purl.uniprot.org/uniprot/G2I2K9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell inner membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/634177:GLX_RS02785 ^@ http://purl.uniprot.org/uniprot/G2I496 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/634177:GLX_RS11735 ^@ http://purl.uniprot.org/uniprot/G2I157 ^@ Similarity ^@ Belongs to the TrbG/VirB9 family. http://togogenome.org/gene/634177:GLX_RS02750 ^@ http://purl.uniprot.org/uniprot/G2I491 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS10985 ^@ http://purl.uniprot.org/uniprot/G2I0R5 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/634177:GLX_RS04830 ^@ http://purl.uniprot.org/uniprot/G2I5D3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/634177:GLX_RS06620 ^@ http://purl.uniprot.org/uniprot/G2I6C6 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/634177:GLX_RS15130 ^@ http://purl.uniprot.org/uniprot/G2I843 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/634177:GLX_RS09070 ^@ http://purl.uniprot.org/uniprot/G2I7P6 ^@ Similarity ^@ Belongs to the XFP family. http://togogenome.org/gene/634177:GLX_RS13690 ^@ http://purl.uniprot.org/uniprot/G2I2T4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/634177:GLX_RS05380 ^@ http://purl.uniprot.org/uniprot/G2I5P3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/634177:GLX_RS04940 ^@ http://purl.uniprot.org/uniprot/G2I5F5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/634177:GLX_RS05185 ^@ http://purl.uniprot.org/uniprot/G2I5K4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptD family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS05660 ^@ http://purl.uniprot.org/uniprot/G2I5U9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS03450 ^@ http://purl.uniprot.org/uniprot/G2I4M3 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/634177:GLX_RS03685 ^@ http://purl.uniprot.org/uniprot/G2I4R9 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/634177:GLX_RS14825 ^@ http://purl.uniprot.org/uniprot/G2I7X9 ^@ Similarity ^@ Belongs to the virb1 family. http://togogenome.org/gene/634177:GLX_RS11105 ^@ http://purl.uniprot.org/uniprot/G2I0T9 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/634177:GLX_RS03490 ^@ http://purl.uniprot.org/uniprot/G2I4N1 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/634177:GLX_RS05550 ^@ http://purl.uniprot.org/uniprot/G2I5S7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/634177:GLX_RS10785 ^@ http://purl.uniprot.org/uniprot/G2I0M7 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS01155 ^@ http://purl.uniprot.org/uniprot/G2I254 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/634177:GLX_RS05225 ^@ http://purl.uniprot.org/uniprot/G2I5L2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/634177:GLX_RS08375 ^@ http://purl.uniprot.org/uniprot/G2I7B5 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/634177:GLX_RS05270 ^@ http://purl.uniprot.org/uniprot/G2I5M1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS12045 ^@ http://purl.uniprot.org/uniprot/G2I1C4 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/634177:GLX_RS13365 ^@ http://purl.uniprot.org/uniprot/G2I2L9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/634177:GLX_RS13050 ^@ http://purl.uniprot.org/uniprot/G2I200 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/634177:GLX_RS12935 ^@ http://purl.uniprot.org/uniprot/G2I1X6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/634177:GLX_RS14530 ^@ http://purl.uniprot.org/uniprot/G2I3Q6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/634177:GLX_RS14555 ^@ http://purl.uniprot.org/uniprot/G2I7S4 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/634177:GLX_RS04205 ^@ http://purl.uniprot.org/uniprot/G2I521 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/634177:GLX_RS05070 ^@ http://purl.uniprot.org/uniprot/G2I5I1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS01425 ^@ http://purl.uniprot.org/uniprot/G2I388 ^@ Function|||Similarity ^@ Belongs to the DadA oxidoreductase family.|||Oxidative deamination of D-amino acids. http://togogenome.org/gene/634177:GLX_RS09520 ^@ http://purl.uniprot.org/uniprot/G2HZX2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/634177:GLX_RS06485 ^@ http://purl.uniprot.org/uniprot/G2I699 ^@ Cofactor|||Similarity ^@ Belongs to the nitroreductase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/634177:GLX_RS09980 ^@ http://purl.uniprot.org/uniprot/G2I069 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||The active site is located at the dimer interface. http://togogenome.org/gene/634177:GLX_RS16300 ^@ http://purl.uniprot.org/uniprot/G2I8T8 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/634177:GLX_RS07540 ^@ http://purl.uniprot.org/uniprot/G2I6V1 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS01345 ^@ http://purl.uniprot.org/uniprot/G2I373 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily. http://togogenome.org/gene/634177:GLX_RS00470 ^@ http://purl.uniprot.org/uniprot/G2I287 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/634177:GLX_RS03095 ^@ http://purl.uniprot.org/uniprot/G2I4F5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/634177:GLX_RS11545 ^@ http://purl.uniprot.org/uniprot/G2I125 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/634177:GLX_RS01370 ^@ http://purl.uniprot.org/uniprot/G2I378 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS07155 ^@ http://purl.uniprot.org/uniprot/G2I6M7 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/634177:GLX_RS03040 ^@ http://purl.uniprot.org/uniprot/G2I4E4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/634177:GLX_RS13010 ^@ http://purl.uniprot.org/uniprot/G2I1Z1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/634177:GLX_RS03945 ^@ http://purl.uniprot.org/uniprot/G2I4X0 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/634177:GLX_RS13610 ^@ http://purl.uniprot.org/uniprot/G2I2R8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/634177:GLX_RS14840 ^@ http://purl.uniprot.org/uniprot/G2I7Y2 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/634177:GLX_RS06190 ^@ http://purl.uniprot.org/uniprot/G2I650 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/634177:GLX_RS12105 ^@ http://purl.uniprot.org/uniprot/G2I1D8 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/634177:GLX_RS14445 ^@ http://purl.uniprot.org/uniprot/G2I3P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. YfcJ family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS04360 ^@ http://purl.uniprot.org/uniprot/G2I551 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS07055 ^@ http://purl.uniprot.org/uniprot/G2I6K8 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/634177:GLX_RS10515 ^@ http://purl.uniprot.org/uniprot/G2I0H4 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/634177:GLX_RS12860 ^@ http://purl.uniprot.org/uniprot/G2I1W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP12 family.|||Mitochondrion http://togogenome.org/gene/634177:GLX_RS04270 ^@ http://purl.uniprot.org/uniprot/G2I533 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS11660 ^@ http://purl.uniprot.org/uniprot/G2I142 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HsdR family.|||Subunit R is required for both nuclease and ATPase activities, but not for modification.|||The type I restriction/modification system is composed of three polypeptides R, M and S. http://togogenome.org/gene/634177:GLX_RS12225 ^@ http://purl.uniprot.org/uniprot/G2I1G5 ^@ Similarity ^@ Belongs to the PhzF family. http://togogenome.org/gene/634177:GLX_RS10500 ^@ http://purl.uniprot.org/uniprot/G2I0H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/634177:GLX_RS05160 ^@ http://purl.uniprot.org/uniprot/G2I5J9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/634177:GLX_RS00970 ^@ http://purl.uniprot.org/uniprot/G2I2Z6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS12745 ^@ http://purl.uniprot.org/uniprot/G2I1T9 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/634177:GLX_RS05465 ^@ http://purl.uniprot.org/uniprot/G2I5R0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/634177:GLX_RS10325 ^@ http://purl.uniprot.org/uniprot/G2I0D7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/634177:GLX_RS08390 ^@ http://purl.uniprot.org/uniprot/G2I7B8 ^@ Caution|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/634177:GLX_RS14505 ^@ http://purl.uniprot.org/uniprot/G2I3Q1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/634177:GLX_RS05155 ^@ http://purl.uniprot.org/uniprot/G2I5J8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol monophosphatase superfamily. CysQ family.|||Cell inner membrane|||Converts adenosine-3',5'-bisphosphate (PAP) to AMP. http://togogenome.org/gene/634177:GLX_RS13960 ^@ http://purl.uniprot.org/uniprot/G2I3F1 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/634177:GLX_RS05615 ^@ http://purl.uniprot.org/uniprot/G2I5U0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/634177:GLX_RS08975 ^@ http://purl.uniprot.org/uniprot/G2I7M5 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/634177:GLX_RS12815 ^@ http://purl.uniprot.org/uniprot/G2I1V3 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/634177:GLX_RS14525 ^@ http://purl.uniprot.org/uniprot/G2I3Q5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/634177:GLX_RS07025 ^@ http://purl.uniprot.org/uniprot/G2I6K2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/634177:GLX_RS09555 ^@ http://purl.uniprot.org/uniprot/G2HZX9 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.|||Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.|||Homodimer.|||In the C-terminal section; belongs to the cytidylyltransferase family.|||In the N-terminal section; belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/634177:GLX_RS02835 ^@ http://purl.uniprot.org/uniprot/G2I4A4 ^@ Function ^@ Multidrug efflux pump. http://togogenome.org/gene/634177:GLX_RS07960 ^@ http://purl.uniprot.org/uniprot/G2I736 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/634177:GLX_RS00680 ^@ http://purl.uniprot.org/uniprot/G2I2C9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/634177:GLX_RS10540 ^@ http://purl.uniprot.org/uniprot/G2I0H9 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/634177:GLX_RS10680 ^@ http://purl.uniprot.org/uniprot/G2I0K6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueG family.|||Binds 2 [4Fe-4S] clusters per monomer.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/634177:GLX_RS10670 ^@ http://purl.uniprot.org/uniprot/G2I0K4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/634177:GLX_RS07905 ^@ http://purl.uniprot.org/uniprot/G2I725 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/634177:GLX_RS12700 ^@ http://purl.uniprot.org/uniprot/G2I1T0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/634177:GLX_RS03850 ^@ http://purl.uniprot.org/uniprot/G2I4V2 ^@ Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily. http://togogenome.org/gene/634177:GLX_RS00155 ^@ http://purl.uniprot.org/uniprot/G2I228 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/634177:GLX_RS13890 ^@ http://purl.uniprot.org/uniprot/G2I2X5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS11370 ^@ http://purl.uniprot.org/uniprot/G2I0Z2 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/634177:GLX_RS04555 ^@ http://purl.uniprot.org/uniprot/G2I582 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/634177:GLX_RS05825 ^@ http://purl.uniprot.org/uniprot/G2I5Y2 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/634177:GLX_RS10120 ^@ http://purl.uniprot.org/uniprot/G2I096 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/634177:GLX_RS12640 ^@ http://purl.uniprot.org/uniprot/G2I1R8 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/634177:GLX_RS10890 ^@ http://purl.uniprot.org/uniprot/G2I0P7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/634177:GLX_RS15075 ^@ http://purl.uniprot.org/uniprot/G2I831 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS04850 ^@ http://purl.uniprot.org/uniprot/G2I5D7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/634177:GLX_RS04405 ^@ http://purl.uniprot.org/uniprot/G2I558 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.|||Cell inner membrane|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine. http://togogenome.org/gene/634177:GLX_RS10160 ^@ http://purl.uniprot.org/uniprot/G2I0A4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/634177:GLX_RS13980 ^@ http://purl.uniprot.org/uniprot/G2I3F5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/634177:GLX_RS16530 ^@ http://purl.uniprot.org/uniprot/G2I772 ^@ Similarity ^@ Belongs to the virb1 family. http://togogenome.org/gene/634177:GLX_RS10875 ^@ http://purl.uniprot.org/uniprot/G2I0P4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/634177:GLX_RS03965 ^@ http://purl.uniprot.org/uniprot/G2I4X4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS06545 ^@ http://purl.uniprot.org/uniprot/G2I6B1 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/634177:GLX_RS05345 ^@ http://purl.uniprot.org/uniprot/G2I5N6 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/634177:GLX_RS01955 ^@ http://purl.uniprot.org/uniprot/G2I3U6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS12730 ^@ http://purl.uniprot.org/uniprot/G2I1T6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/634177:GLX_RS17475 ^@ http://purl.uniprot.org/uniprot/G2I1C5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS10495 ^@ http://purl.uniprot.org/uniprot/G2I0H0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/634177:GLX_RS06560 ^@ http://purl.uniprot.org/uniprot/G2I6B4 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/634177:GLX_RS04280 ^@ http://purl.uniprot.org/uniprot/G2I535 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS04880 ^@ http://purl.uniprot.org/uniprot/G2I5E3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/634177:GLX_RS01500 ^@ http://purl.uniprot.org/uniprot/G2I3A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic sulfate-binding protein family.|||Periplasm http://togogenome.org/gene/634177:GLX_RS04575 ^@ http://purl.uniprot.org/uniprot/G2I586 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/634177:GLX_RS13130 ^@ http://purl.uniprot.org/uniprot/G2I216 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/634177:GLX_RS03410 ^@ http://purl.uniprot.org/uniprot/G2I4L6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/634177:GLX_RS13380 ^@ http://purl.uniprot.org/uniprot/G2I2M2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Binds 1 nickel ion per subunit.|||Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/634177:GLX_RS14495 ^@ http://purl.uniprot.org/uniprot/G2I3P9 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/634177:GLX_RS03320 ^@ http://purl.uniprot.org/uniprot/G2I4J9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.|||Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.|||Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).|||Homodimer or monomer when oxidized or reduced, respectively.|||chloroplast http://togogenome.org/gene/634177:GLX_RS04285 ^@ http://purl.uniprot.org/uniprot/G2I536 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS15795 ^@ http://purl.uniprot.org/uniprot/G2I8I5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/634177:GLX_RS07470 ^@ http://purl.uniprot.org/uniprot/G2I6T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/634177:GLX_RS03690 ^@ http://purl.uniprot.org/uniprot/G2I4S0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/634177:GLX_RS10250 ^@ http://purl.uniprot.org/uniprot/G2I0C2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS05195 ^@ http://purl.uniprot.org/uniprot/G2I5K6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/634177:GLX_RS04955 ^@ http://purl.uniprot.org/uniprot/G2I5F8 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/634177:GLX_RS06005 ^@ http://purl.uniprot.org/uniprot/G2I615 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the reversible phosphorylation of pyruvate and phosphate. http://togogenome.org/gene/634177:GLX_RS05635 ^@ http://purl.uniprot.org/uniprot/G2I5U4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/634177:GLX_RS02280 ^@ http://purl.uniprot.org/uniprot/G2I407 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/634177:GLX_RS07875 ^@ http://purl.uniprot.org/uniprot/G2I719 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS10945 ^@ http://purl.uniprot.org/uniprot/G2I0Q8 ^@ Similarity|||Subunit ^@ Belongs to the P(II) protein family.|||Homotrimer. http://togogenome.org/gene/634177:GLX_RS09935 ^@ http://purl.uniprot.org/uniprot/G2I061 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/634177:GLX_RS01995 ^@ http://purl.uniprot.org/uniprot/G2I3V4 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/634177:GLX_RS03145 ^@ http://purl.uniprot.org/uniprot/G2I4G5 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/634177:GLX_RS13710 ^@ http://purl.uniprot.org/uniprot/G2I2T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS04055 ^@ http://purl.uniprot.org/uniprot/G2I4Z2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/634177:GLX_RS03230 ^@ http://purl.uniprot.org/uniprot/G2I4I1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/634177:GLX_RS04545 ^@ http://purl.uniprot.org/uniprot/G2I580 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/634177:GLX_RS05500 ^@ http://purl.uniprot.org/uniprot/G2I5R7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/634177:GLX_RS04860 ^@ http://purl.uniprot.org/uniprot/G2I5D9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Cell inner membrane|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/634177:GLX_RS10035 ^@ http://purl.uniprot.org/uniprot/G2I080 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/634177:GLX_RS00750 ^@ http://purl.uniprot.org/uniprot/G2I2E3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/634177:GLX_RS09260 ^@ http://purl.uniprot.org/uniprot/G2HZS2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b family.|||Binds 2 heme groups non-covalently.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/634177:GLX_RS02965 ^@ http://purl.uniprot.org/uniprot/G2I4C9 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/634177:GLX_RS12655 ^@ http://purl.uniprot.org/uniprot/G2I1S1 ^@ Function|||Subunit ^@ Homotetramer.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/634177:GLX_RS05725 ^@ http://purl.uniprot.org/uniprot/G2I5W1 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/634177:GLX_RS05510 ^@ http://purl.uniprot.org/uniprot/G2I5R9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/634177:GLX_RS03855 ^@ http://purl.uniprot.org/uniprot/G2I4V3 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/634177:GLX_RS10265 ^@ http://purl.uniprot.org/uniprot/G2I0C5 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein. http://togogenome.org/gene/634177:GLX_RS13275 ^@ http://purl.uniprot.org/uniprot/G2I2K1 ^@ Similarity ^@ Belongs to the MQO family. http://togogenome.org/gene/634177:GLX_RS10455 ^@ http://purl.uniprot.org/uniprot/G2I0G3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.|||Homodimer. http://togogenome.org/gene/634177:GLX_RS13250 ^@ http://purl.uniprot.org/uniprot/G2I2J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS14100 ^@ http://purl.uniprot.org/uniprot/G2I3H9 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/634177:GLX_RS02055 ^@ http://purl.uniprot.org/uniprot/G2I3W5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/634177:GLX_RS05455 ^@ http://purl.uniprot.org/uniprot/G2I5Q8 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/634177:GLX_RS09305 ^@ http://purl.uniprot.org/uniprot/G2HZT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/634177:GLX_RS07270 ^@ http://purl.uniprot.org/uniprot/G2I6Q0 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/634177:GLX_RS11505 ^@ http://purl.uniprot.org/uniprot/G2I117 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/634177:GLX_RS12840 ^@ http://purl.uniprot.org/uniprot/G2I1V8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/634177:GLX_RS15090 ^@ http://purl.uniprot.org/uniprot/G2I834 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS00695 ^@ http://purl.uniprot.org/uniprot/G2I2D3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS10755 ^@ http://purl.uniprot.org/uniprot/G2I0M1 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/634177:GLX_RS12410 ^@ http://purl.uniprot.org/uniprot/G2I1M3 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/634177:GLX_RS04650 ^@ http://purl.uniprot.org/uniprot/G2I598 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS09335 ^@ http://purl.uniprot.org/uniprot/G2HZT7 ^@ Function ^@ Acts on leucine, isoleucine and valine. http://togogenome.org/gene/634177:GLX_RS01685 ^@ http://purl.uniprot.org/uniprot/G2I3D8 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/634177:GLX_RS05540 ^@ http://purl.uniprot.org/uniprot/G2I5S5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/634177:GLX_RS10145 ^@ http://purl.uniprot.org/uniprot/G2I0A1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/634177:GLX_RS11650 ^@ http://purl.uniprot.org/uniprot/G2I140 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/634177:GLX_RS07865 ^@ http://purl.uniprot.org/uniprot/G2I717 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS15735 ^@ http://purl.uniprot.org/uniprot/G2I8H5 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/634177:GLX_RS13825 ^@ http://purl.uniprot.org/uniprot/G2I2W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS06140 ^@ http://purl.uniprot.org/uniprot/G2I640 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS02015 ^@ http://purl.uniprot.org/uniprot/G2I3V8 ^@ Similarity ^@ Belongs to the dihydropyrimidine dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS10175 ^@ http://purl.uniprot.org/uniprot/G2I0A7 ^@ Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/634177:GLX_RS05920 ^@ http://purl.uniprot.org/uniprot/G2I600 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/634177:GLX_RS03460 ^@ http://purl.uniprot.org/uniprot/G2I4M5 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/634177:GLX_RS13660 ^@ http://purl.uniprot.org/uniprot/G2I2S8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Cytoplasm|||Homodimer.|||Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. http://togogenome.org/gene/634177:GLX_RS03935 ^@ http://purl.uniprot.org/uniprot/G2I4W8 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/634177:GLX_RS15230 ^@ http://purl.uniprot.org/uniprot/G2I866 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/634177:GLX_RS00135 ^@ http://purl.uniprot.org/uniprot/G2I224 ^@ Function|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. http://togogenome.org/gene/634177:GLX_RS12425 ^@ http://purl.uniprot.org/uniprot/G2I1M6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/634177:GLX_RS10230 ^@ http://purl.uniprot.org/uniprot/G2I0B8 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/634177:GLX_RS06775 ^@ http://purl.uniprot.org/uniprot/G2I6F7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS09450 ^@ http://purl.uniprot.org/uniprot/G2HZV8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/634177:GLX_RS04970 ^@ http://purl.uniprot.org/uniprot/G2I5G1 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/634177:GLX_RS15250 ^@ http://purl.uniprot.org/uniprot/G2I870 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/634177:GLX_RS04230 ^@ http://purl.uniprot.org/uniprot/G2I526 ^@ Similarity ^@ Belongs to the UPF0335 family. http://togogenome.org/gene/634177:GLX_RS12380 ^@ http://purl.uniprot.org/uniprot/G2I1L7 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/634177:GLX_RS03215 ^@ http://purl.uniprot.org/uniprot/G2I4H8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS10555 ^@ http://purl.uniprot.org/uniprot/G2I0I2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS05560 ^@ http://purl.uniprot.org/uniprot/G2I5S9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/634177:GLX_RS11470 ^@ http://purl.uniprot.org/uniprot/G2I110 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS13020 ^@ http://purl.uniprot.org/uniprot/G2I1Z4 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/634177:GLX_RS10910 ^@ http://purl.uniprot.org/uniprot/G2I0Q1 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/634177:GLX_RS02880 ^@ http://purl.uniprot.org/uniprot/G2I4B3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/634177:GLX_RS06565 ^@ http://purl.uniprot.org/uniprot/G2I6B5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/634177:GLX_RS10370 ^@ http://purl.uniprot.org/uniprot/G2I0E6 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/634177:GLX_RS10235 ^@ http://purl.uniprot.org/uniprot/G2I0B9 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/634177:GLX_RS02905 ^@ http://purl.uniprot.org/uniprot/G2I4B8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/634177:GLX_RS11295 ^@ http://purl.uniprot.org/uniprot/G2I0X7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/634177:GLX_RS09610 ^@ http://purl.uniprot.org/uniprot/G2HZZ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/634177:GLX_RS09515 ^@ http://purl.uniprot.org/uniprot/G2HZX1 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/634177:GLX_RS03600 ^@ http://purl.uniprot.org/uniprot/G2I4Q2 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/634177:GLX_RS13270 ^@ http://purl.uniprot.org/uniprot/G2I2K0 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/634177:GLX_RS13615 ^@ http://purl.uniprot.org/uniprot/G2I2R9 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/634177:GLX_RS11455 ^@ http://purl.uniprot.org/uniprot/G2I107 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS05830 ^@ http://purl.uniprot.org/uniprot/G2I5Y3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/634177:GLX_RS01835 ^@ http://purl.uniprot.org/uniprot/G2I3S3 ^@ Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family. http://togogenome.org/gene/634177:GLX_RS04275 ^@ http://purl.uniprot.org/uniprot/G2I534 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/634177:GLX_RS12565 ^@ http://purl.uniprot.org/uniprot/G2I1Q4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/634177:GLX_RS10395 ^@ http://purl.uniprot.org/uniprot/G2I0F1 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/634177:GLX_RS12340 ^@ http://purl.uniprot.org/uniprot/G2I1I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS01860 ^@ http://purl.uniprot.org/uniprot/G2I3S7 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/634177:GLX_RS04855 ^@ http://purl.uniprot.org/uniprot/G2I5D8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/634177:GLX_RS10270 ^@ http://purl.uniprot.org/uniprot/G2I0C6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS09240 ^@ http://purl.uniprot.org/uniprot/G2HZR9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/634177:GLX_RS09330 ^@ http://purl.uniprot.org/uniprot/G2HZT6 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/634177:GLX_RS08585 ^@ http://purl.uniprot.org/uniprot/G2I7F9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/634177:GLX_RS13955 ^@ http://purl.uniprot.org/uniprot/G2I3F0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/634177:GLX_RS03880 ^@ http://purl.uniprot.org/uniprot/G2I4V8 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/634177:GLX_RS06040 ^@ http://purl.uniprot.org/uniprot/G2I621 ^@ Cofactor ^@ Binds 3 heme c groups covalently per subunit. http://togogenome.org/gene/634177:GLX_RS09495 ^@ http://purl.uniprot.org/uniprot/G2HZW7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. PqqE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).|||Interacts with PqqD. The interaction is necessary for activity of PqqE. http://togogenome.org/gene/634177:GLX_RS03205 ^@ http://purl.uniprot.org/uniprot/G2I4H6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.|||Cell membrane|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/634177:GLX_RS07750 ^@ http://purl.uniprot.org/uniprot/G2I6Z0 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/634177:GLX_RS17025 ^@ http://purl.uniprot.org/uniprot/G2I5T6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/634177:GLX_RS03395 ^@ http://purl.uniprot.org/uniprot/G2I4L3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/634177:GLX_RS11385 ^@ http://purl.uniprot.org/uniprot/G2I0Z5 ^@ Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family. http://togogenome.org/gene/634177:GLX_RS16225 ^@ http://purl.uniprot.org/uniprot/G2I8S1 ^@ Similarity ^@ Belongs to the transposase IS21/IS408/IS1162 family. http://togogenome.org/gene/634177:GLX_RS19240 ^@ http://purl.uniprot.org/uniprot/G2I2J2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/634177:GLX_RS11940 ^@ http://purl.uniprot.org/uniprot/G2I197 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/634177:GLX_RS11700 ^@ http://purl.uniprot.org/uniprot/G2I150 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/634177:GLX_RS13170 ^@ http://purl.uniprot.org/uniprot/G2I2I1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS10770 ^@ http://purl.uniprot.org/uniprot/G2I0M4 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family.|||Homodimer. http://togogenome.org/gene/634177:GLX_RS12770 ^@ http://purl.uniprot.org/uniprot/G2I1U4 ^@ Function|||Similarity ^@ Belongs to the thioredoxin family. DsbA subfamily.|||May be required for disulfide bond formation in some proteins. http://togogenome.org/gene/634177:GLX_RS15820 ^@ http://purl.uniprot.org/uniprot/G2I8J0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Cell membrane|||Involved in arsenical resistance. Thought to form the channel of an arsenite pump.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/634177:GLX_RS06480 ^@ http://purl.uniprot.org/uniprot/G2I698 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/634177:GLX_RS15760 ^@ http://purl.uniprot.org/uniprot/G2I8H8 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/634177:GLX_RS09235 ^@ http://purl.uniprot.org/uniprot/G2HZR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS12170 ^@ http://purl.uniprot.org/uniprot/G2I1F1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS13640 ^@ http://purl.uniprot.org/uniprot/G2I2S4 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/634177:GLX_RS06555 ^@ http://purl.uniprot.org/uniprot/G2I6B3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell inner membrane|||Probably interacts with PlsX. http://togogenome.org/gene/634177:GLX_RS14880 ^@ http://purl.uniprot.org/uniprot/G2I7Z2 ^@ Similarity ^@ Belongs to the HipA Ser/Thr kinase family. http://togogenome.org/gene/634177:GLX_RS11510 ^@ http://purl.uniprot.org/uniprot/G2I118 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/634177:GLX_RS08495 ^@ http://purl.uniprot.org/uniprot/G2I7D9 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/634177:GLX_RS13560 ^@ http://purl.uniprot.org/uniprot/G2I2Q8 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/634177:GLX_RS06965 ^@ http://purl.uniprot.org/uniprot/G2I6J0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/634177:GLX_RS05210 ^@ http://purl.uniprot.org/uniprot/G2I5K9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/634177:GLX_RS02815 ^@ http://purl.uniprot.org/uniprot/G2I4A1 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/634177:GLX_RS13575 ^@ http://purl.uniprot.org/uniprot/G2I2R1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M32 family.|||Binds 1 zinc ion per subunit.|||Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. http://togogenome.org/gene/634177:GLX_RS06500 ^@ http://purl.uniprot.org/uniprot/G2I6A2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/634177:GLX_RS00210 ^@ http://purl.uniprot.org/uniprot/G2I239 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/634177:GLX_RS05250 ^@ http://purl.uniprot.org/uniprot/G2I5L7 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/634177:GLX_RS08840 ^@ http://purl.uniprot.org/uniprot/G2I7J8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS05890 ^@ http://purl.uniprot.org/uniprot/G2I5Z5 ^@ Cofactor ^@ Binds 3 heme c groups covalently per subunit. http://togogenome.org/gene/634177:GLX_RS01385 ^@ http://purl.uniprot.org/uniprot/G2I381 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/634177:GLX_RS14090 ^@ http://purl.uniprot.org/uniprot/G2I3H7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/634177:GLX_RS04235 ^@ http://purl.uniprot.org/uniprot/G2I527 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS06340 ^@ http://purl.uniprot.org/uniprot/G2I675 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS04800 ^@ http://purl.uniprot.org/uniprot/G2I5C7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/634177:GLX_RS06805 ^@ http://purl.uniprot.org/uniprot/G2I6G3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/634177:GLX_RS02780 ^@ http://purl.uniprot.org/uniprot/G2I495 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/634177:GLX_RS10975 ^@ http://purl.uniprot.org/uniprot/G2I0R3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/634177:GLX_RS04570 ^@ http://purl.uniprot.org/uniprot/G2I585 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/634177:GLX_RS15195 ^@ http://purl.uniprot.org/uniprot/G2I857 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LysR transcriptional regulatory family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS05735 ^@ http://purl.uniprot.org/uniprot/G2I5W4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell inner membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/634177:GLX_RS13515 ^@ http://purl.uniprot.org/uniprot/G2I2P8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/634177:GLX_RS15240 ^@ http://purl.uniprot.org/uniprot/G2I868 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS13295 ^@ http://purl.uniprot.org/uniprot/G2I2K5 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/634177:GLX_RS13545 ^@ http://purl.uniprot.org/uniprot/G2I2Q4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell inner membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/634177:GLX_RS10285 ^@ http://purl.uniprot.org/uniprot/G2I0C9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS09150 ^@ http://purl.uniprot.org/uniprot/G2I7R2 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/634177:GLX_RS04325 ^@ http://purl.uniprot.org/uniprot/G2I544 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/634177:GLX_RS12530 ^@ http://purl.uniprot.org/uniprot/G2I1P7 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/634177:GLX_RS11000 ^@ http://purl.uniprot.org/uniprot/G2I0R9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS08965 ^@ http://purl.uniprot.org/uniprot/G2I7M3 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/634177:GLX_RS13770 ^@ http://purl.uniprot.org/uniprot/G2I2V0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/634177:GLX_RS07400 ^@ http://purl.uniprot.org/uniprot/G2I6S6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/634177:GLX_RS07075 ^@ http://purl.uniprot.org/uniprot/G2I6L2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/634177:GLX_RS02740 ^@ http://purl.uniprot.org/uniprot/G2I489 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/634177:GLX_RS10920 ^@ http://purl.uniprot.org/uniprot/G2I0Q3 ^@ Function|||Similarity ^@ Belongs to the AMP nucleosidase family.|||Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. http://togogenome.org/gene/634177:GLX_RS02735 ^@ http://purl.uniprot.org/uniprot/G2I488 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/634177:GLX_RS13290 ^@ http://purl.uniprot.org/uniprot/G2I2K4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/634177:GLX_RS10820 ^@ http://purl.uniprot.org/uniprot/G2I0N4 ^@ Similarity ^@ Belongs to the fructosamine kinase family. http://togogenome.org/gene/634177:GLX_RS03190 ^@ http://purl.uniprot.org/uniprot/G2I4H3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS03150 ^@ http://purl.uniprot.org/uniprot/G2I4G6 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/634177:GLX_RS06510 ^@ http://purl.uniprot.org/uniprot/G2I6A4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/634177:GLX_RS14025 ^@ http://purl.uniprot.org/uniprot/G2I3G5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell inner membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/634177:GLX_RS12580 ^@ http://purl.uniprot.org/uniprot/G2I1Q7 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/634177:GLX_RS13500 ^@ http://purl.uniprot.org/uniprot/G2I2P5 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/634177:GLX_RS07900 ^@ http://purl.uniprot.org/uniprot/G2I724 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS03325 ^@ http://purl.uniprot.org/uniprot/G2I4K0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/634177:GLX_RS09855 ^@ http://purl.uniprot.org/uniprot/G2I046 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/634177:GLX_RS07345 ^@ http://purl.uniprot.org/uniprot/G2I6R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS12945 ^@ http://purl.uniprot.org/uniprot/G2I1X8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/634177:GLX_RS11760 ^@ http://purl.uniprot.org/uniprot/G2I162 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/634177:GLX_RS15790 ^@ http://purl.uniprot.org/uniprot/G2I8I4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP E family.|||Cytoplasm|||Part of the Type IV secretion system. http://togogenome.org/gene/634177:GLX_RS14685 ^@ http://purl.uniprot.org/uniprot/G2I7U7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/634177:GLX_RS15930 ^@ http://purl.uniprot.org/uniprot/G2I8L0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell inner membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/634177:GLX_RS04890 ^@ http://purl.uniprot.org/uniprot/G2I5E5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/634177:GLX_RS04730 ^@ http://purl.uniprot.org/uniprot/G2I5B4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/634177:GLX_RS03860 ^@ http://purl.uniprot.org/uniprot/G2I4V4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/634177:GLX_RS12445 ^@ http://purl.uniprot.org/uniprot/G2I1N0 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/634177:GLX_RS10810 ^@ http://purl.uniprot.org/uniprot/G2I0N2 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/634177:GLX_RS10675 ^@ http://purl.uniprot.org/uniprot/G2I0K5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/634177:GLX_RS03650 ^@ http://purl.uniprot.org/uniprot/G2I4R2 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/634177:GLX_RS08345 ^@ http://purl.uniprot.org/uniprot/G2I6X3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/634177:GLX_RS10045 ^@ http://purl.uniprot.org/uniprot/G2I082 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/634177:GLX_RS03065 ^@ http://purl.uniprot.org/uniprot/G2I4E9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/634177:GLX_RS01390 ^@ http://purl.uniprot.org/uniprot/G2I382 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS05925 ^@ http://purl.uniprot.org/uniprot/G2I601 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Cob(I)alamin adenosyltransferase family.|||Cytoplasm|||Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. http://togogenome.org/gene/634177:GLX_RS09815 ^@ http://purl.uniprot.org/uniprot/G2I038 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS01325 ^@ http://purl.uniprot.org/uniprot/G2I369 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/634177:GLX_RS07655 ^@ http://purl.uniprot.org/uniprot/G2I6X1 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS11725 ^@ http://purl.uniprot.org/uniprot/G2I155 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbL/VirB6 family.|||Membrane http://togogenome.org/gene/634177:GLX_RS03535 ^@ http://purl.uniprot.org/uniprot/G2I4N9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/634177:GLX_RS09310 ^@ http://purl.uniprot.org/uniprot/G2HZT2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/634177:GLX_RS02060 ^@ http://purl.uniprot.org/uniprot/G2I3W6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/634177:GLX_RS05450 ^@ http://purl.uniprot.org/uniprot/G2I5Q7 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/634177:GLX_RS01490 ^@ http://purl.uniprot.org/uniprot/G2I3A1 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/634177:GLX_RS00555 ^@ http://purl.uniprot.org/uniprot/G2I6X3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/634177:GLX_RS04550 ^@ http://purl.uniprot.org/uniprot/G2I581 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS01430 ^@ http://purl.uniprot.org/uniprot/G2I389 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/634177:GLX_RS10330 ^@ http://purl.uniprot.org/uniprot/G2I0D8 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/634177:GLX_RS09595 ^@ http://purl.uniprot.org/uniprot/G2HZY7 ^@ Function|||Similarity ^@ Belongs to the folylpolyglutamate synthase family.|||Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. http://togogenome.org/gene/634177:GLX_RS12825 ^@ http://purl.uniprot.org/uniprot/G2I1V5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/634177:GLX_RS09010 ^@ http://purl.uniprot.org/uniprot/G2I7N3 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/634177:GLX_RS00675 ^@ http://purl.uniprot.org/uniprot/G2I2C8 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/634177:GLX_RS12665 ^@ http://purl.uniprot.org/uniprot/G2I1S3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/634177:GLX_RS10870 ^@ http://purl.uniprot.org/uniprot/G2I0P3 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/634177:GLX_RS00835 ^@ http://purl.uniprot.org/uniprot/G2I2F9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS15190 ^@ http://purl.uniprot.org/uniprot/G2I856 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/634177:GLX_RS09975 ^@ http://purl.uniprot.org/uniprot/G2I068 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/634177:GLX_RS16195 ^@ http://purl.uniprot.org/uniprot/G2I8R5 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/634177:GLX_RS00075 ^@ http://purl.uniprot.org/uniprot/G2I1K5 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/634177:GLX_RS12485 ^@ http://purl.uniprot.org/uniprot/G2I1N8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS09760 ^@ http://purl.uniprot.org/uniprot/G2I254 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/634177:GLX_RS04655 ^@ http://purl.uniprot.org/uniprot/G2I599 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS06630 ^@ http://purl.uniprot.org/uniprot/G2I6C8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/634177:GLX_RS03565 ^@ http://purl.uniprot.org/uniprot/G2I4P5 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/634177:GLX_RS12605 ^@ http://purl.uniprot.org/uniprot/G2I1R2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/634177:GLX_RS01715 ^@ http://purl.uniprot.org/uniprot/G2I3E4 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/634177:GLX_RS12435 ^@ http://purl.uniprot.org/uniprot/G2I1M8 ^@ Function ^@ Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation. http://togogenome.org/gene/634177:GLX_RS06735 ^@ http://purl.uniprot.org/uniprot/G2I6E9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/634177:GLX_RS04345 ^@ http://purl.uniprot.org/uniprot/G2I548 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS15815 ^@ http://purl.uniprot.org/uniprot/G2I8I9 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/634177:GLX_RS09430 ^@ http://purl.uniprot.org/uniprot/G2HZV4 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/634177:GLX_RS07190 ^@ http://purl.uniprot.org/uniprot/G2I6N4 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/634177:GLX_RS00665 ^@ http://purl.uniprot.org/uniprot/G2I2C6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/634177:GLX_RS06225 ^@ http://purl.uniprot.org/uniprot/G2I657 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/634177:GLX_RS08555 ^@ http://purl.uniprot.org/uniprot/G2I7F3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS11965 ^@ http://purl.uniprot.org/uniprot/G2I1A2 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/634177:GLX_RS15000 ^@ http://purl.uniprot.org/uniprot/G2I816 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/634177:GLX_RS14415 ^@ http://purl.uniprot.org/uniprot/G2I3N5 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/634177:GLX_RS03485 ^@ http://purl.uniprot.org/uniprot/G2I4N0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS09600 ^@ http://purl.uniprot.org/uniprot/G2HZY8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS00565 ^@ http://purl.uniprot.org/uniprot/G2I2A7 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/634177:GLX_RS12750 ^@ http://purl.uniprot.org/uniprot/G2I1U0 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS11535 ^@ http://purl.uniprot.org/uniprot/G2I123 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/634177:GLX_RS01225 ^@ http://purl.uniprot.org/uniprot/G2I349 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/634177:GLX_RS08870 ^@ http://purl.uniprot.org/uniprot/G2I7K4 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/634177:GLX_RS12440 ^@ http://purl.uniprot.org/uniprot/G2I1M9 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.|||Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation. http://togogenome.org/gene/634177:GLX_RS06055 ^@ http://purl.uniprot.org/uniprot/G2I624 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS12625 ^@ http://purl.uniprot.org/uniprot/G2I1R6 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/634177:GLX_RS04600 ^@ http://purl.uniprot.org/uniprot/G2I591 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/634177:GLX_RS09125 ^@ http://purl.uniprot.org/uniprot/G2I7Q7 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/634177:GLX_RS16250 ^@ http://purl.uniprot.org/uniprot/G2I8S6 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/634177:GLX_RS10080 ^@ http://purl.uniprot.org/uniprot/G2I088 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/634177:GLX_RS01975 ^@ http://purl.uniprot.org/uniprot/G2I3V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS10645 ^@ http://purl.uniprot.org/uniprot/G2I0J9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/634177:GLX_RS05385 ^@ http://purl.uniprot.org/uniprot/G2I5P4 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/634177:GLX_RS03200 ^@ http://purl.uniprot.org/uniprot/G2I4H5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the R-transferase family. Bpt subfamily.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. http://togogenome.org/gene/634177:GLX_RS04250 ^@ http://purl.uniprot.org/uniprot/G2I529 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/634177:GLX_RS00165 ^@ http://purl.uniprot.org/uniprot/G2I230 ^@ Similarity ^@ Belongs to the fatty acid desaturase type 2 family. http://togogenome.org/gene/634177:GLX_RS13810 ^@ http://purl.uniprot.org/uniprot/G2I2V9 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/634177:GLX_RS05420 ^@ http://purl.uniprot.org/uniprot/G2I5Q1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/634177:GLX_RS13590 ^@ http://purl.uniprot.org/uniprot/G2I2R4 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/634177:GLX_RS11365 ^@ http://purl.uniprot.org/uniprot/G2I0Z1 ^@ Function|||Similarity ^@ Belongs to the trehalose phosphatase family.|||Removes the phosphate from trehalose 6-phosphate to produce free trehalose. http://togogenome.org/gene/634177:GLX_RS13595 ^@ http://purl.uniprot.org/uniprot/G2I2R5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/634177:GLX_RS13415 ^@ http://purl.uniprot.org/uniprot/G2I2M9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/634177:GLX_RS13565 ^@ http://purl.uniprot.org/uniprot/G2I2Q9 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/634177:GLX_RS10550 ^@ http://purl.uniprot.org/uniprot/G2I0I1 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/634177:GLX_RS14665 ^@ http://purl.uniprot.org/uniprot/G2I7U3 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/634177:GLX_RS05590 ^@ http://purl.uniprot.org/uniprot/G2I5T5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/634177:GLX_RS07000 ^@ http://purl.uniprot.org/uniprot/G2I6J7 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/634177:GLX_RS04195 ^@ http://purl.uniprot.org/uniprot/G2I520 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. http://togogenome.org/gene/634177:GLX_RS15780 ^@ http://purl.uniprot.org/uniprot/G2I8I2 ^@ Similarity ^@ Belongs to the TrbG/VirB9 family. http://togogenome.org/gene/634177:GLX_RS12740 ^@ http://purl.uniprot.org/uniprot/G2I1T8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/634177:GLX_RS13945 ^@ http://purl.uniprot.org/uniprot/G2I2Y6 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/634177:GLX_RS10400 ^@ http://purl.uniprot.org/uniprot/G2I0F2 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/634177:GLX_RS05970 ^@ http://purl.uniprot.org/uniprot/G2I610 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/634177:GLX_RS04715 ^@ http://purl.uniprot.org/uniprot/G2I5B1 ^@ Function ^@ Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. http://togogenome.org/gene/634177:GLX_RS11320 ^@ http://purl.uniprot.org/uniprot/G2I0Y2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/634177:GLX_RS06670 ^@ http://purl.uniprot.org/uniprot/G2I6D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS05330 ^@ http://purl.uniprot.org/uniprot/G2I5N3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS15150 ^@ http://purl.uniprot.org/uniprot/G2I848 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/634177:GLX_RS12690 ^@ http://purl.uniprot.org/uniprot/G2I1S8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/634177:GLX_RS10615 ^@ http://purl.uniprot.org/uniprot/G2I0J3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/634177:GLX_RS12050 ^@ http://purl.uniprot.org/uniprot/G2I1C6 ^@ Caution|||Cofactor|||Similarity ^@ Belongs to the WrbA family.|||Binds 1 FMN per monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS04780 ^@ http://purl.uniprot.org/uniprot/G2I5C3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/634177:GLX_RS09315 ^@ http://purl.uniprot.org/uniprot/G2HZT3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell inner membrane|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/634177:GLX_RS07005 ^@ http://purl.uniprot.org/uniprot/G2I6J8 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/634177:GLX_RS07530 ^@ http://purl.uniprot.org/uniprot/G2I6U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS03955 ^@ http://purl.uniprot.org/uniprot/G2I4X2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/634177:GLX_RS05515 ^@ http://purl.uniprot.org/uniprot/G2I5S0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/634177:GLX_RS03085 ^@ http://purl.uniprot.org/uniprot/G2I4F3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/634177:GLX_RS16635 ^@ http://purl.uniprot.org/uniprot/G2I133 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/634177:GLX_RS04775 ^@ http://purl.uniprot.org/uniprot/G2I5C2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/634177:GLX_RS05820 ^@ http://purl.uniprot.org/uniprot/G2I5Y1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/634177:GLX_RS02950 ^@ http://purl.uniprot.org/uniprot/G2I4C7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/634177:GLX_RS04950 ^@ http://purl.uniprot.org/uniprot/G2I5F7 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/634177:GLX_RS12550 ^@ http://purl.uniprot.org/uniprot/G2I1Q2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase E/G family. RNase E subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per homotetramer.|||Cell inner membrane|||Cytoplasm|||Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.|||Homotetramer formed by a dimer of dimers. http://togogenome.org/gene/634177:GLX_RS04315 ^@ http://purl.uniprot.org/uniprot/G2I542 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. http://togogenome.org/gene/634177:GLX_RS00200 ^@ http://purl.uniprot.org/uniprot/G2I237 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS03560 ^@ http://purl.uniprot.org/uniprot/G2I4P4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/634177:GLX_RS03810 ^@ http://purl.uniprot.org/uniprot/G2I4U4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/634177:GLX_RS03875 ^@ http://purl.uniprot.org/uniprot/G2I4V7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/634177:GLX_RS03255 ^@ http://purl.uniprot.org/uniprot/G2I4I6 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/634177:GLX_RS07160 ^@ http://purl.uniprot.org/uniprot/G2I6M8 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/634177:GLX_RS03890 ^@ http://purl.uniprot.org/uniprot/G2I4W0 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/634177:GLX_RS14650 ^@ http://purl.uniprot.org/uniprot/G2I7U0 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/634177:GLX_RS06535 ^@ http://purl.uniprot.org/uniprot/G2I6A9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS09475 ^@ http://purl.uniprot.org/uniprot/G2HZW3 ^@ Function|||Similarity ^@ Belongs to the PqqA family.|||Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide. http://togogenome.org/gene/634177:GLX_RS10415 ^@ http://purl.uniprot.org/uniprot/G2I0F5 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/634177:GLX_RS00095 ^@ http://purl.uniprot.org/uniprot/G2I1L0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS12115 ^@ http://purl.uniprot.org/uniprot/G2I1D9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS15030 ^@ http://purl.uniprot.org/uniprot/G2I822 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/634177:GLX_RS03495 ^@ http://purl.uniprot.org/uniprot/G2I4N2 ^@ Function|||Similarity ^@ Belongs to the esterase D family.|||Serine hydrolase involved in the detoxification of formaldehyde. http://togogenome.org/gene/634177:GLX_RS05995 ^@ http://purl.uniprot.org/uniprot/G2I613 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit. http://togogenome.org/gene/634177:GLX_RS05480 ^@ http://purl.uniprot.org/uniprot/G2I5R3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/634177:GLX_RS05980 ^@ http://purl.uniprot.org/uniprot/G2I612 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS01320 ^@ http://purl.uniprot.org/uniprot/G2I368 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/634177:GLX_RS01120 ^@ http://purl.uniprot.org/uniprot/G2I327 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the encapsulin family. Family 1 subfamily.|||Encapsulin nanocompartment http://togogenome.org/gene/634177:GLX_RS05100 ^@ http://purl.uniprot.org/uniprot/G2I5I7 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/634177:GLX_RS00435 ^@ http://purl.uniprot.org/uniprot/G2I280 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/634177:GLX_RS01930 ^@ http://purl.uniprot.org/uniprot/G2I3U1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/634177:GLX_RS02990 ^@ http://purl.uniprot.org/uniprot/G2I4D4 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/634177:GLX_RS10190 ^@ http://purl.uniprot.org/uniprot/G2I0B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/634177:GLX_RS16170 ^@ http://purl.uniprot.org/uniprot/G2I8R0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer.|||Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). http://togogenome.org/gene/634177:GLX_RS01555 ^@ http://purl.uniprot.org/uniprot/G2I3B3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/634177:GLX_RS14510 ^@ http://purl.uniprot.org/uniprot/G2I3Q2 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/634177:GLX_RS03220 ^@ http://purl.uniprot.org/uniprot/G2I4H9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/634177:GLX_RS03350 ^@ http://purl.uniprot.org/uniprot/G2I4K5 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/634177:GLX_RS04590 ^@ http://purl.uniprot.org/uniprot/G2I589 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/634177:GLX_RS08855 ^@ http://purl.uniprot.org/uniprot/G2I7K1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/634177:GLX_RS05785 ^@ http://purl.uniprot.org/uniprot/G2I5X4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS04170 ^@ http://purl.uniprot.org/uniprot/G2I515 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/634177:GLX_RS09740 ^@ http://purl.uniprot.org/uniprot/G2I015 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/634177:GLX_RS03675 ^@ http://purl.uniprot.org/uniprot/G2I4R7 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/634177:GLX_RS04525 ^@ http://purl.uniprot.org/uniprot/G2I576 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/634177:GLX_RS01080 ^@ http://purl.uniprot.org/uniprot/G2I319 ^@ Similarity ^@ Belongs to the OprB family. http://togogenome.org/gene/634177:GLX_RS16415 ^@ http://purl.uniprot.org/uniprot/G2I269 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/634177:GLX_RS03920 ^@ http://purl.uniprot.org/uniprot/G2I4W6 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/634177:GLX_RS05205 ^@ http://purl.uniprot.org/uniprot/G2I5K8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/634177:GLX_RS15295 ^@ http://purl.uniprot.org/uniprot/G2I878 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/634177:GLX_RS05700 ^@ http://purl.uniprot.org/uniprot/G2I5V7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/634177:GLX_RS08750 ^@ http://purl.uniprot.org/uniprot/G2I6X3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/634177:GLX_RS01455 ^@ http://purl.uniprot.org/uniprot/G2I394 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/634177:GLX_RS04180 ^@ http://purl.uniprot.org/uniprot/G2I517 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS12250 ^@ http://purl.uniprot.org/uniprot/G2I1H0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS15880 ^@ http://purl.uniprot.org/uniprot/G2I8K1 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/634177:GLX_RS13400 ^@ http://purl.uniprot.org/uniprot/G2I2M6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell inner membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/634177:GLX_RS09345 ^@ http://purl.uniprot.org/uniprot/G2HZT9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/634177:GLX_RS09435 ^@ http://purl.uniprot.org/uniprot/G2HZV5 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/634177:GLX_RS13335 ^@ http://purl.uniprot.org/uniprot/G2I2L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/634177:GLX_RS06870 ^@ http://purl.uniprot.org/uniprot/G2I6H4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/634177:GLX_RS05740 ^@ http://purl.uniprot.org/uniprot/G2I5W5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS12175 ^@ http://purl.uniprot.org/uniprot/G2I254 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/634177:GLX_RS05790 ^@ http://purl.uniprot.org/uniprot/G2I5X5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/634177:GLX_RS01805 ^@ http://purl.uniprot.org/uniprot/G2I3R7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS10110 ^@ http://purl.uniprot.org/uniprot/G2I094 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/634177:GLX_RS12255 ^@ http://purl.uniprot.org/uniprot/G2I1H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/634177:GLX_RS14185 ^@ http://purl.uniprot.org/uniprot/G2I254 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/634177:GLX_RS13390 ^@ http://purl.uniprot.org/uniprot/G2I2M4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/634177:GLX_RS00980 ^@ http://purl.uniprot.org/uniprot/G2I254 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/634177:GLX_RS04330 ^@ http://purl.uniprot.org/uniprot/G2I545 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/634177:GLX_RS05525 ^@ http://purl.uniprot.org/uniprot/G2I5S2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/634177:GLX_RS09710 ^@ http://purl.uniprot.org/uniprot/G2I6X3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/634177:GLX_RS13345 ^@ http://purl.uniprot.org/uniprot/G2I2L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/634177:GLX_RS04725 ^@ http://purl.uniprot.org/uniprot/G2I5B3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS08135 ^@ http://purl.uniprot.org/uniprot/G2I0T9 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/634177:GLX_RS10830 ^@ http://purl.uniprot.org/uniprot/G2I0N5 ^@ Function|||Similarity ^@ Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.|||Belongs to the AhpD family. http://togogenome.org/gene/634177:GLX_RS04620 ^@ http://purl.uniprot.org/uniprot/G2I593 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/634177:GLX_RS10815 ^@ http://purl.uniprot.org/uniprot/G2I0N3 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/634177:GLX_RS16210 ^@ http://purl.uniprot.org/uniprot/G2I8R8 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/634177:GLX_RS09870 ^@ http://purl.uniprot.org/uniprot/G2I048 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/634177:GLX_RS04805 ^@ http://purl.uniprot.org/uniprot/G2I5C8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/634177:GLX_RS10840 ^@ http://purl.uniprot.org/uniprot/G2I0N7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/634177:GLX_RS07285 ^@ http://purl.uniprot.org/uniprot/G2I6Q3 ^@ Similarity ^@ Belongs to the virb1 family. http://togogenome.org/gene/634177:GLX_RS00450 ^@ http://purl.uniprot.org/uniprot/G2I282 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/634177:GLX_RS11495 ^@ http://purl.uniprot.org/uniprot/G2I115 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/634177:GLX_RS03455 ^@ http://purl.uniprot.org/uniprot/G2I4M4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/634177:GLX_RS11520 ^@ http://purl.uniprot.org/uniprot/G2I120 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS13555 ^@ http://purl.uniprot.org/uniprot/G2I2Q7 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/634177:GLX_RS05530 ^@ http://purl.uniprot.org/uniprot/G2I5S3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/634177:GLX_RS06610 ^@ http://purl.uniprot.org/uniprot/G2I6C4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/634177:GLX_RS12780 ^@ http://purl.uniprot.org/uniprot/G2I1U6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS01825 ^@ http://purl.uniprot.org/uniprot/G2I3S1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/634177:GLX_RS09145 ^@ http://purl.uniprot.org/uniprot/G2I7R1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS06615 ^@ http://purl.uniprot.org/uniprot/G2I6C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/634177:GLX_RS03670 ^@ http://purl.uniprot.org/uniprot/G2I4R6 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS04690 ^@ http://purl.uniprot.org/uniprot/G2I5A6 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/634177:GLX_RS01165 ^@ http://purl.uniprot.org/uniprot/G2I337 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.|||Cytoplasm http://togogenome.org/gene/634177:GLX_RS09155 ^@ http://purl.uniprot.org/uniprot/G2I7R3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||Homodimer.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/634177:GLX_RS09485 ^@ http://purl.uniprot.org/uniprot/G2HZW5 ^@ Function|||Similarity ^@ Belongs to the PqqC family.|||Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ. http://togogenome.org/gene/634177:GLX_RS04580 ^@ http://purl.uniprot.org/uniprot/G2I587 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/634177:GLX_RS16285 ^@ http://purl.uniprot.org/uniprot/G2I8T4 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/634177:GLX_RS07420 ^@ http://purl.uniprot.org/uniprot/G2I6T0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/634177:GLX_RS04875 ^@ http://purl.uniprot.org/uniprot/G2I5E2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/634177:GLX_RS07630 ^@ http://purl.uniprot.org/uniprot/G2I6W6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/634177:GLX_RS00265 ^@ http://purl.uniprot.org/uniprot/G2I250 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/634177:GLX_RS13745 ^@ http://purl.uniprot.org/uniprot/G2I2U5 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/634177:GLX_RS11715 ^@ http://purl.uniprot.org/uniprot/G2I153 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/634177:GLX_RS03940 ^@ http://purl.uniprot.org/uniprot/G2I4W9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||Forms a 24-polypeptide structural core with octahedral symmetry.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/634177:GLX_RS06770 ^@ http://purl.uniprot.org/uniprot/G2I6F6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS03990 ^@ http://purl.uniprot.org/uniprot/G2I4X9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/634177:GLX_RS07050 ^@ http://purl.uniprot.org/uniprot/G2I6K7 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/634177:GLX_RS03645 ^@ http://purl.uniprot.org/uniprot/G2I4R1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/634177:GLX_RS10135 ^@ http://purl.uniprot.org/uniprot/G2I099 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/634177:GLX_RS08560 ^@ http://purl.uniprot.org/uniprot/G2I7F4 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/634177:GLX_RS08255 ^@ http://purl.uniprot.org/uniprot/G2I794 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/634177:GLX_RS13025 ^@ http://purl.uniprot.org/uniprot/G2I1Z5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/634177:GLX_RS15770 ^@ http://purl.uniprot.org/uniprot/G2I8I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbL/VirB6 family.|||Membrane http://togogenome.org/gene/634177:GLX_RS06650 ^@ http://purl.uniprot.org/uniprot/G2I6D2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds 1 Fe(2+) cation per monomer.|||Binds 1 nickel ion per monomer.|||Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Monomer. http://togogenome.org/gene/634177:GLX_RS14005 ^@ http://purl.uniprot.org/uniprot/G2I3G1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds the 23S rRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the 50S ribosomal subunit.