http://togogenome.org/gene/758793:BRPE64_RS02975 ^@ http://purl.uniprot.org/uniprot/R4WFQ2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS09145 ^@ http://purl.uniprot.org/uniprot/R4WRT7 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS04235 ^@ http://purl.uniprot.org/uniprot/R4WUM0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.|||Cytoplasm|||Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity. http://togogenome.org/gene/758793:BRPE64_RS19570 ^@ http://purl.uniprot.org/uniprot/R4WMU8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS29540 ^@ http://purl.uniprot.org/uniprot/R4X101 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS09390 ^@ http://purl.uniprot.org/uniprot/R4WZ91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS19965 ^@ http://purl.uniprot.org/uniprot/R4X300 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS19315 ^@ http://purl.uniprot.org/uniprot/R4WMG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhE family.|||Cytoplasm|||Necessary for formate dehydrogenase activity. http://togogenome.org/gene/758793:BRPE64_RS31115 ^@ http://purl.uniprot.org/uniprot/A0A060PKE7 ^@ Similarity ^@ Belongs to the nitrile hydratase subunit alpha family. http://togogenome.org/gene/758793:BRPE64_RS04360 ^@ http://purl.uniprot.org/uniprot/R4WFW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/758793:BRPE64_RS25400 ^@ http://purl.uniprot.org/uniprot/R4WR81 ^@ Similarity ^@ Belongs to the bacterial PQQ dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS23875 ^@ http://purl.uniprot.org/uniprot/R4X3W3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS08375 ^@ http://purl.uniprot.org/uniprot/R4WHE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS27965 ^@ http://purl.uniprot.org/uniprot/R4X3S1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS30170 ^@ http://purl.uniprot.org/uniprot/R4X184 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.|||Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.|||Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.|||Periplasm|||Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. http://togogenome.org/gene/758793:BRPE64_RS12035 ^@ http://purl.uniprot.org/uniprot/R4WIR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS00240 ^@ http://purl.uniprot.org/uniprot/R4WSF7 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/758793:BRPE64_RS28410 ^@ http://purl.uniprot.org/uniprot/R4X4Z5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS14085 ^@ http://purl.uniprot.org/uniprot/R4WJS0 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/758793:BRPE64_RS11725 ^@ http://purl.uniprot.org/uniprot/R4WY95 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/758793:BRPE64_RS17830 ^@ http://purl.uniprot.org/uniprot/R4WLJ0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/758793:BRPE64_RS12355 ^@ http://purl.uniprot.org/uniprot/R4WTM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/758793:BRPE64_RS06285 ^@ http://purl.uniprot.org/uniprot/R4WGR7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS11835 ^@ http://purl.uniprot.org/uniprot/R4X041 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/758793:BRPE64_RS02740 ^@ http://purl.uniprot.org/uniprot/R4WFN0 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/758793:BRPE64_RS18900 ^@ http://purl.uniprot.org/uniprot/R4X2K1 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/758793:BRPE64_RS20780 ^@ http://purl.uniprot.org/uniprot/R4X1E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS09525 ^@ http://purl.uniprot.org/uniprot/R4WHP8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/758793:BRPE64_RS09960 ^@ http://purl.uniprot.org/uniprot/R4WHY8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/758793:BRPE64_RS10430 ^@ http://purl.uniprot.org/uniprot/R4WHZ5 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/758793:BRPE64_RS23220 ^@ http://purl.uniprot.org/uniprot/R4X2B4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS00765 ^@ http://purl.uniprot.org/uniprot/R4WEY8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS13545 ^@ http://purl.uniprot.org/uniprot/R4WJC5 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/758793:BRPE64_RS02010 ^@ http://purl.uniprot.org/uniprot/R4WF45 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS19035 ^@ http://purl.uniprot.org/uniprot/R4WMH6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS11550 ^@ http://purl.uniprot.org/uniprot/R4WIM5 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/758793:BRPE64_RS00930 ^@ http://purl.uniprot.org/uniprot/R4WF05 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/758793:BRPE64_RS02455 ^@ http://purl.uniprot.org/uniprot/R4WFK1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS12390 ^@ http://purl.uniprot.org/uniprot/R4X0C5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/758793:BRPE64_RS24805 ^@ http://purl.uniprot.org/uniprot/R4X2W1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/758793:BRPE64_RS25440 ^@ http://purl.uniprot.org/uniprot/R4WR92 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/758793:BRPE64_RS13520 ^@ http://purl.uniprot.org/uniprot/R4X0P9 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/758793:BRPE64_RS15770 ^@ http://purl.uniprot.org/uniprot/R4WKP0 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/758793:BRPE64_RS08475 ^@ http://purl.uniprot.org/uniprot/R4WRF1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS04465 ^@ http://purl.uniprot.org/uniprot/R4WP61 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/758793:BRPE64_RS00600 ^@ http://purl.uniprot.org/uniprot/R4WEN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS25760 ^@ http://purl.uniprot.org/uniprot/R4WR67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the urea transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS01030 ^@ http://purl.uniprot.org/uniprot/R4WF15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS11380 ^@ http://purl.uniprot.org/uniprot/R4WIE4 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/758793:BRPE64_RS28240 ^@ http://purl.uniprot.org/uniprot/R4X4X7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS06195 ^@ http://purl.uniprot.org/uniprot/R4WVS0 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS00120 ^@ http://purl.uniprot.org/uniprot/R4WSD4 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/758793:BRPE64_RS04300 ^@ http://purl.uniprot.org/uniprot/R4WP14 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/758793:BRPE64_RS17070 ^@ http://purl.uniprot.org/uniprot/R4WL76 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS00965 ^@ http://purl.uniprot.org/uniprot/R4WSU1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/758793:BRPE64_RS00440 ^@ http://purl.uniprot.org/uniprot/R4WEV3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS05470 ^@ http://purl.uniprot.org/uniprot/R4WG98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS22020 ^@ http://purl.uniprot.org/uniprot/R4WNY5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS15575 ^@ http://purl.uniprot.org/uniprot/R4X1G1 ^@ Cofactor ^@ Binds 1 Ca(2+) ion per subunit. http://togogenome.org/gene/758793:BRPE64_RS04255 ^@ http://purl.uniprot.org/uniprot/R4WP04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS28530 ^@ http://purl.uniprot.org/uniprot/R4WT39 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS22045 ^@ http://purl.uniprot.org/uniprot/R4WNZ0 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/758793:BRPE64_RS01595 ^@ http://purl.uniprot.org/uniprot/R4WEZ7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS08405 ^@ http://purl.uniprot.org/uniprot/R4WX16 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/758793:BRPE64_RS06300 ^@ http://purl.uniprot.org/uniprot/R4WY31 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/758793:BRPE64_RS29135 ^@ http://purl.uniprot.org/uniprot/R4X428 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/758793:BRPE64_RS08630 ^@ http://purl.uniprot.org/uniprot/R4WX50 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS09360 ^@ http://purl.uniprot.org/uniprot/R4WHM1 ^@ Function|||Subunit ^@ DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease. http://togogenome.org/gene/758793:BRPE64_RS24470 ^@ http://purl.uniprot.org/uniprot/R4WZ36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS05270 ^@ http://purl.uniprot.org/uniprot/R4WG82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS25875 ^@ http://purl.uniprot.org/uniprot/R4X4D3 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/758793:BRPE64_RS03925 ^@ http://purl.uniprot.org/uniprot/R4WUG9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/758793:BRPE64_RS10715 ^@ http://purl.uniprot.org/uniprot/R4WXW8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS31740 ^@ http://purl.uniprot.org/uniprot/A0A060PRD1 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/758793:BRPE64_RS04265 ^@ http://purl.uniprot.org/uniprot/R4WXB3 ^@ Similarity ^@ Belongs to the PhzF family. http://togogenome.org/gene/758793:BRPE64_RS14895 ^@ http://purl.uniprot.org/uniprot/R4WV05 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS06665 ^@ http://purl.uniprot.org/uniprot/R4WW07 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS22210 ^@ http://purl.uniprot.org/uniprot/R4WPA3 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/758793:BRPE64_RS05825 ^@ http://purl.uniprot.org/uniprot/R4WGL8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/758793:BRPE64_RS18365 ^@ http://purl.uniprot.org/uniprot/R4WWV2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Cob(I)alamin adenosyltransferase family.|||Cytoplasm|||Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. http://togogenome.org/gene/758793:BRPE64_RS06320 ^@ http://purl.uniprot.org/uniprot/R4WVU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS22750 ^@ http://purl.uniprot.org/uniprot/R4X3M7 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/758793:BRPE64_RS18570 ^@ http://purl.uniprot.org/uniprot/R4X2G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS01885 ^@ http://purl.uniprot.org/uniprot/R4WTC0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS25430 ^@ http://purl.uniprot.org/uniprot/R4X494 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/758793:BRPE64_RS15860 ^@ http://purl.uniprot.org/uniprot/R4WKR1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS06775 ^@ http://purl.uniprot.org/uniprot/R4WQH7 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/758793:BRPE64_RS02615 ^@ http://purl.uniprot.org/uniprot/R4WTU8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS01690 ^@ http://purl.uniprot.org/uniprot/R4WW09 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/758793:BRPE64_RS14640 ^@ http://purl.uniprot.org/uniprot/R4WK42 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. PqqE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).|||Interacts with PqqD. The interaction is necessary for activity of PqqE. http://togogenome.org/gene/758793:BRPE64_RS19430 ^@ http://purl.uniprot.org/uniprot/R4WMS8 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/758793:BRPE64_RS16780 ^@ http://purl.uniprot.org/uniprot/R4WL36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS05560 ^@ http://purl.uniprot.org/uniprot/R4WXU7 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/758793:BRPE64_RS01860 ^@ http://purl.uniprot.org/uniprot/R4WTB4 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/758793:BRPE64_RS31470 ^@ http://purl.uniprot.org/uniprot/A0A060PKN1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS01525 ^@ http://purl.uniprot.org/uniprot/R4WEY7 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/758793:BRPE64_RS06765 ^@ http://purl.uniprot.org/uniprot/R4WGR0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS11050 ^@ http://purl.uniprot.org/uniprot/R4WZU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CpoB family.|||Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS29400 ^@ http://purl.uniprot.org/uniprot/R4X563 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS10230 ^@ http://purl.uniprot.org/uniprot/R4WHW9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/758793:BRPE64_RS23545 ^@ http://purl.uniprot.org/uniprot/R4WPU4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS08315 ^@ http://purl.uniprot.org/uniprot/R4WYV1 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/758793:BRPE64_RS31710 ^@ http://purl.uniprot.org/uniprot/A0A060PHD8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/758793:BRPE64_RS10145 ^@ http://purl.uniprot.org/uniprot/R4WZI9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS01500 ^@ http://purl.uniprot.org/uniprot/R4WVX9 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/758793:BRPE64_RS00885 ^@ http://purl.uniprot.org/uniprot/R4WM67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiK family.|||Cytoplasm|||Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both. http://togogenome.org/gene/758793:BRPE64_RS12015 ^@ http://purl.uniprot.org/uniprot/R4WIX3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/758793:BRPE64_RS13080 ^@ http://purl.uniprot.org/uniprot/R4WJB1 ^@ Function|||Similarity ^@ Belongs to the FliK family.|||Controls the length of the flagellar hook. http://togogenome.org/gene/758793:BRPE64_RS16055 ^@ http://purl.uniprot.org/uniprot/R4WKV2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS17360 ^@ http://purl.uniprot.org/uniprot/R4X235 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS05700 ^@ http://purl.uniprot.org/uniprot/R4WXW5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/758793:BRPE64_RS02700 ^@ http://purl.uniprot.org/uniprot/R4WFM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS03055 ^@ http://purl.uniprot.org/uniprot/R4WU29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS19935 ^@ http://purl.uniprot.org/uniprot/R4WXH4 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/758793:BRPE64_RS09020 ^@ http://purl.uniprot.org/uniprot/R4WHM5 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/758793:BRPE64_RS16935 ^@ http://purl.uniprot.org/uniprot/R4WLE7 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/758793:BRPE64_RS08120 ^@ http://purl.uniprot.org/uniprot/R4WR91 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS10065 ^@ http://purl.uniprot.org/uniprot/R4WHV0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS12125 ^@ http://purl.uniprot.org/uniprot/R4X095 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS05070 ^@ http://purl.uniprot.org/uniprot/R4WXN8 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS04935 ^@ http://purl.uniprot.org/uniprot/R4WPJ9 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/758793:BRPE64_RS14745 ^@ http://purl.uniprot.org/uniprot/R4WK57 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS05720 ^@ http://purl.uniprot.org/uniprot/R4WXW7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/758793:BRPE64_RS04640 ^@ http://purl.uniprot.org/uniprot/R4WXH1 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.|||Belongs to the RecC family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/758793:BRPE64_RS06240 ^@ http://purl.uniprot.org/uniprot/R4WQ65 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/758793:BRPE64_RS07620 ^@ http://purl.uniprot.org/uniprot/R4WYN0 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.|||Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA. http://togogenome.org/gene/758793:BRPE64_RS03715 ^@ http://purl.uniprot.org/uniprot/R4WX55 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/758793:BRPE64_RS30395 ^@ http://purl.uniprot.org/uniprot/R4X4D2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS07555 ^@ http://purl.uniprot.org/uniprot/R4WH59 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/758793:BRPE64_RS30255 ^@ http://purl.uniprot.org/uniprot/R4WU37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS15495 ^@ http://purl.uniprot.org/uniprot/R4WKI3 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS04780 ^@ http://purl.uniprot.org/uniprot/R4WXK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS14295 ^@ http://purl.uniprot.org/uniprot/R4WJQ1 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS01985 ^@ http://purl.uniprot.org/uniprot/R4WF42 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS13105 ^@ http://purl.uniprot.org/uniprot/R4WJB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/758793:BRPE64_RS16575 ^@ http://purl.uniprot.org/uniprot/R4WKX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS27925 ^@ http://purl.uniprot.org/uniprot/R4WSL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS32095 ^@ http://purl.uniprot.org/uniprot/R4WPE4 ^@ Caution|||Similarity ^@ Belongs to the UPF0391 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS27805 ^@ http://purl.uniprot.org/uniprot/R4WSI1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS30700 ^@ http://purl.uniprot.org/uniprot/R4X1I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS07560 ^@ http://purl.uniprot.org/uniprot/R4WQZ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS19740 ^@ http://purl.uniprot.org/uniprot/R4WMM5 ^@ Function|||Similarity ^@ Belongs to the GTP cyclohydrolase IV family.|||Converts GTP to 7,8-dihydroneopterin triphosphate. http://togogenome.org/gene/758793:BRPE64_RS31265 ^@ http://purl.uniprot.org/uniprot/A0A060PQY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS23620 ^@ http://purl.uniprot.org/uniprot/R4WPW2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/758793:BRPE64_RS03750 ^@ http://purl.uniprot.org/uniprot/R4WFX2 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS18310 ^@ http://purl.uniprot.org/uniprot/R4X2D9 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/758793:BRPE64_RS24980 ^@ http://purl.uniprot.org/uniprot/R4WQX0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS15935 ^@ http://purl.uniprot.org/uniprot/R4WVK2 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/758793:BRPE64_RS30070 ^@ http://purl.uniprot.org/uniprot/R4WU28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS23525 ^@ http://purl.uniprot.org/uniprot/R4WPT9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS26110 ^@ http://purl.uniprot.org/uniprot/R4X3A6 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/758793:BRPE64_RS01145 ^@ http://purl.uniprot.org/uniprot/R4WEU0 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS19545 ^@ http://purl.uniprot.org/uniprot/R4WMU5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS27970 ^@ http://purl.uniprot.org/uniprot/R4X4V5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS22375 ^@ http://purl.uniprot.org/uniprot/R4X200 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS02710 ^@ http://purl.uniprot.org/uniprot/R4WWR1 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/758793:BRPE64_RS14755 ^@ http://purl.uniprot.org/uniprot/R4WZC6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS11200 ^@ http://purl.uniprot.org/uniprot/R4WIB1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS03985 ^@ http://purl.uniprot.org/uniprot/R4WFR7 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/758793:BRPE64_RS01970 ^@ http://purl.uniprot.org/uniprot/R4WMS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS31530 ^@ http://purl.uniprot.org/uniprot/A0A060PR49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS28050 ^@ http://purl.uniprot.org/uniprot/R4WSP7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS03910 ^@ http://purl.uniprot.org/uniprot/R4WFQ8 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS16940 ^@ http://purl.uniprot.org/uniprot/R4WW38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/758793:BRPE64_RS06620 ^@ http://purl.uniprot.org/uniprot/R4WY82 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/758793:BRPE64_RS01135 ^@ http://purl.uniprot.org/uniprot/R4WSX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/758793:BRPE64_RS08920 ^@ http://purl.uniprot.org/uniprot/R4WRN6 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/758793:BRPE64_RS14335 ^@ http://purl.uniprot.org/uniprot/R4WZ76 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/758793:BRPE64_RS01895 ^@ http://purl.uniprot.org/uniprot/R4WF30 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS16300 ^@ http://purl.uniprot.org/uniprot/R4WL04 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS11795 ^@ http://purl.uniprot.org/uniprot/R4WYA5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbC subfamily.|||Periplasm|||Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. http://togogenome.org/gene/758793:BRPE64_RS25595 ^@ http://purl.uniprot.org/uniprot/R4X4A7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS05940 ^@ http://purl.uniprot.org/uniprot/R4WGF5 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/758793:BRPE64_RS11545 ^@ http://purl.uniprot.org/uniprot/R4WIG9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/758793:BRPE64_RS20285 ^@ http://purl.uniprot.org/uniprot/R4WMX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS01250 ^@ http://purl.uniprot.org/uniprot/R4WEV2 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/758793:BRPE64_RS27765 ^@ http://purl.uniprot.org/uniprot/R4WSG8 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/758793:BRPE64_RS08495 ^@ http://purl.uniprot.org/uniprot/R4WHG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS28685 ^@ http://purl.uniprot.org/uniprot/R4X0Q9 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/758793:BRPE64_RS10450 ^@ http://purl.uniprot.org/uniprot/R4WHZ8 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/758793:BRPE64_RS22545 ^@ http://purl.uniprot.org/uniprot/R4X221 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS13665 ^@ http://purl.uniprot.org/uniprot/R4WYY2 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/758793:BRPE64_RS10795 ^@ http://purl.uniprot.org/uniprot/R4WSR6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS21785 ^@ http://purl.uniprot.org/uniprot/R4WNV5 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/758793:BRPE64_RS23185 ^@ http://purl.uniprot.org/uniprot/R4X3R1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the CoA-transferase III family. Frc subfamily.|||Homodimer.|||Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS08165 ^@ http://purl.uniprot.org/uniprot/R4WR99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HscB family.|||Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.|||Interacts with HscA and stimulates its ATPase activity. http://togogenome.org/gene/758793:BRPE64_RS02195 ^@ http://purl.uniprot.org/uniprot/R4WWC4 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS21490 ^@ http://purl.uniprot.org/uniprot/R4X3C9 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/758793:BRPE64_RS27710 ^@ http://purl.uniprot.org/uniprot/R4X4T4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS06950 ^@ http://purl.uniprot.org/uniprot/R4WYC8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS15570 ^@ http://purl.uniprot.org/uniprot/R4WZM1 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/758793:BRPE64_RS24270 ^@ http://purl.uniprot.org/uniprot/R4WQ96 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/758793:BRPE64_RS10240 ^@ http://purl.uniprot.org/uniprot/R4WSF4 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/758793:BRPE64_RS17775 ^@ http://purl.uniprot.org/uniprot/R4X0E0 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/758793:BRPE64_RS16865 ^@ http://purl.uniprot.org/uniprot/R4WW28 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS03225 ^@ http://purl.uniprot.org/uniprot/R4WNH7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS02545 ^@ http://purl.uniprot.org/uniprot/R4WWN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS31575 ^@ http://purl.uniprot.org/uniprot/A0A060PR70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS31465 ^@ http://purl.uniprot.org/uniprot/A0A060PR34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS15525 ^@ http://purl.uniprot.org/uniprot/R4WZL6 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/758793:BRPE64_RS09355 ^@ http://purl.uniprot.org/uniprot/R4WZ87 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS18930 ^@ http://purl.uniprot.org/uniprot/R4WM61 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/758793:BRPE64_RS20670 ^@ http://purl.uniprot.org/uniprot/R4WXR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/758793:BRPE64_RS08925 ^@ http://purl.uniprot.org/uniprot/R4WX84 ^@ Similarity ^@ Belongs to the truncated hemoglobin family. Group II subfamily. http://togogenome.org/gene/758793:BRPE64_RS14035 ^@ http://purl.uniprot.org/uniprot/R4WZ34 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/758793:BRPE64_RS25420 ^@ http://purl.uniprot.org/uniprot/R4WZE6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/758793:BRPE64_RS06595 ^@ http://purl.uniprot.org/uniprot/R4WY78 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||In the N-terminal section; belongs to the FGAMS family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. http://togogenome.org/gene/758793:BRPE64_RS04655 ^@ http://purl.uniprot.org/uniprot/R4WPB0 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/758793:BRPE64_RS02080 ^@ http://purl.uniprot.org/uniprot/R4WF56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS09335 ^@ http://purl.uniprot.org/uniprot/R4WHL8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS11025 ^@ http://purl.uniprot.org/uniprot/R4WZT8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbB/TolQ family.|||Cell inner membrane|||Membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/758793:BRPE64_RS01195 ^@ http://purl.uniprot.org/uniprot/R4WSY1 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/758793:BRPE64_RS24215 ^@ http://purl.uniprot.org/uniprot/R4X2N8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS25640 ^@ http://purl.uniprot.org/uniprot/R4X4B1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS08620 ^@ http://purl.uniprot.org/uniprot/R4WHH5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxH family.|||Binds 2 Mn(2+) ions per subunit in a binuclear metal center.|||Cell inner membrane|||Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS27240 ^@ http://purl.uniprot.org/uniprot/R4X037 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily. http://togogenome.org/gene/758793:BRPE64_RS15215 ^@ http://purl.uniprot.org/uniprot/R4X1C3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS10600 ^@ http://purl.uniprot.org/uniprot/R4WZP1 ^@ Function|||Similarity ^@ Belongs to the Ap4A hydrolase family.|||Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP. http://togogenome.org/gene/758793:BRPE64_RS26375 ^@ http://purl.uniprot.org/uniprot/R4X4H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS17375 ^@ http://purl.uniprot.org/uniprot/R4X099 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhD family.|||Cytoplasm|||Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.|||The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA. http://togogenome.org/gene/758793:BRPE64_RS28960 ^@ http://purl.uniprot.org/uniprot/R4X528 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS26870 ^@ http://purl.uniprot.org/uniprot/R4X3G6 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/758793:BRPE64_RS10255 ^@ http://purl.uniprot.org/uniprot/R4WHX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/758793:BRPE64_RS14685 ^@ http://purl.uniprot.org/uniprot/R4WK50 ^@ Similarity ^@ Belongs to the HisA/HisF family. http://togogenome.org/gene/758793:BRPE64_RS02770 ^@ http://purl.uniprot.org/uniprot/R4WN96 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS31435 ^@ http://purl.uniprot.org/uniprot/A0A060PH56 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/758793:BRPE64_RS13180 ^@ http://purl.uniprot.org/uniprot/R4WJC7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/758793:BRPE64_RS29460 ^@ http://purl.uniprot.org/uniprot/R4WTM9 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/758793:BRPE64_RS13580 ^@ http://purl.uniprot.org/uniprot/R4WYX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP H family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS09640 ^@ http://purl.uniprot.org/uniprot/R4WZD1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS11845 ^@ http://purl.uniprot.org/uniprot/R4WTC6 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/758793:BRPE64_RS10630 ^@ http://purl.uniprot.org/uniprot/R4WI22 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/758793:BRPE64_RS06545 ^@ http://purl.uniprot.org/uniprot/R4WGN2 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/758793:BRPE64_RS17090 ^@ http://purl.uniprot.org/uniprot/R4WL79 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/758793:BRPE64_RS18050 ^@ http://purl.uniprot.org/uniprot/R4WLX2 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/758793:BRPE64_RS24020 ^@ http://purl.uniprot.org/uniprot/R4WYY8 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS18620 ^@ http://purl.uniprot.org/uniprot/R4WLZ8 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/758793:BRPE64_RS10800 ^@ http://purl.uniprot.org/uniprot/R4WXX9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS26905 ^@ http://purl.uniprot.org/uniprot/R4WRY1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 37 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Periplasm|||Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system. http://togogenome.org/gene/758793:BRPE64_RS10740 ^@ http://purl.uniprot.org/uniprot/R4WZQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. YhhS family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS07645 ^@ http://purl.uniprot.org/uniprot/R4WYN3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/758793:BRPE64_RS21320 ^@ http://purl.uniprot.org/uniprot/R4X3A7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS18370 ^@ http://purl.uniprot.org/uniprot/R4X0K7 ^@ Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily. http://togogenome.org/gene/758793:BRPE64_RS09945 ^@ http://purl.uniprot.org/uniprot/R4WXM5 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS27110 ^@ http://purl.uniprot.org/uniprot/R4WS84 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/758793:BRPE64_RS06780 ^@ http://purl.uniprot.org/uniprot/R4WYA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/758793:BRPE64_RS05205 ^@ http://purl.uniprot.org/uniprot/R4WPP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS04920 ^@ http://purl.uniprot.org/uniprot/R4WV40 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 2 lipoyl cofactors covalently.|||Forms a 24-polypeptide structural core with octahedral symmetry.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/758793:BRPE64_RS22735 ^@ http://purl.uniprot.org/uniprot/R4WPK1 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/758793:BRPE64_RS05740 ^@ http://purl.uniprot.org/uniprot/R4WVI5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/758793:BRPE64_RS13675 ^@ http://purl.uniprot.org/uniprot/R4WJF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/758793:BRPE64_RS28285 ^@ http://purl.uniprot.org/uniprot/R4X3U9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/758793:BRPE64_RS10765 ^@ http://purl.uniprot.org/uniprot/R4WI39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS09395 ^@ http://purl.uniprot.org/uniprot/R4WHM4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyltransferase 20 family.|||Homotetramer.|||Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor. http://togogenome.org/gene/758793:BRPE64_RS11435 ^@ http://purl.uniprot.org/uniprot/R4WT31 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/758793:BRPE64_RS17885 ^@ http://purl.uniprot.org/uniprot/R4WLT9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS30695 ^@ http://purl.uniprot.org/uniprot/R4WUI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS01035 ^@ http://purl.uniprot.org/uniprot/R4WM88 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS11565 ^@ http://purl.uniprot.org/uniprot/R4X012 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/758793:BRPE64_RS00510 ^@ http://purl.uniprot.org/uniprot/R4WEN2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS19435 ^@ http://purl.uniprot.org/uniprot/R4WXC8 ^@ Function ^@ Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY. http://togogenome.org/gene/758793:BRPE64_RS04440 ^@ http://purl.uniprot.org/uniprot/R4WFX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS02005 ^@ http://purl.uniprot.org/uniprot/R4WW75 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/758793:BRPE64_RS14665 ^@ http://purl.uniprot.org/uniprot/R4WK46 ^@ Similarity ^@ Belongs to the FwdC/FmdC family. http://togogenome.org/gene/758793:BRPE64_RS19750 ^@ http://purl.uniprot.org/uniprot/R4WXF6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/758793:BRPE64_RS07285 ^@ http://purl.uniprot.org/uniprot/R4WQU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS19300 ^@ http://purl.uniprot.org/uniprot/R4WXB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS20530 ^@ http://purl.uniprot.org/uniprot/R4WXP3 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/758793:BRPE64_RS26415 ^@ http://purl.uniprot.org/uniprot/R4X3C3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/758793:BRPE64_RS22955 ^@ http://purl.uniprot.org/uniprot/R4WPQ0 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/758793:BRPE64_RS18180 ^@ http://purl.uniprot.org/uniprot/R4WWR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS12405 ^@ http://purl.uniprot.org/uniprot/R4WTM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/758793:BRPE64_RS14840 ^@ http://purl.uniprot.org/uniprot/R4WK73 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/758793:BRPE64_RS23330 ^@ http://purl.uniprot.org/uniprot/R4WPP7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS29020 ^@ http://purl.uniprot.org/uniprot/R4X418 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS27760 ^@ http://purl.uniprot.org/uniprot/R4X4T8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS19930 ^@ http://purl.uniprot.org/uniprot/R4WN05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS09205 ^@ http://purl.uniprot.org/uniprot/R4WXC6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS15170 ^@ http://purl.uniprot.org/uniprot/R4WKC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS17710 ^@ http://purl.uniprot.org/uniprot/R4WLG8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS18325 ^@ http://purl.uniprot.org/uniprot/R4WWU0 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/758793:BRPE64_RS23735 ^@ http://purl.uniprot.org/uniprot/R4X3V6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS09935 ^@ http://purl.uniprot.org/uniprot/R4WHY7 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer. http://togogenome.org/gene/758793:BRPE64_RS18525 ^@ http://purl.uniprot.org/uniprot/R4WLX8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS16000 ^@ http://purl.uniprot.org/uniprot/R4WKJ4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/758793:BRPE64_RS03980 ^@ http://purl.uniprot.org/uniprot/R4WX81 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS08540 ^@ http://purl.uniprot.org/uniprot/R4WHC2 ^@ PTM|||Subcellular Location Annotation ^@ Covalently binds the prosthetic group of malonate decarboxylase.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS06205 ^@ http://purl.uniprot.org/uniprot/R4WGI8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.|||The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ). http://togogenome.org/gene/758793:BRPE64_RS09025 ^@ http://purl.uniprot.org/uniprot/R4WRQ9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/758793:BRPE64_RS27515 ^@ http://purl.uniprot.org/uniprot/R4WSA2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/758793:BRPE64_RS30165 ^@ http://purl.uniprot.org/uniprot/R4WU51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NapD family.|||Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.|||Cytoplasm|||Interacts with the cytoplasmic NapA precursor. http://togogenome.org/gene/758793:BRPE64_RS16945 ^@ http://purl.uniprot.org/uniprot/R4X054 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxine kinase family. PdxY subfamily.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. http://togogenome.org/gene/758793:BRPE64_RS09895 ^@ http://purl.uniprot.org/uniprot/R4WS89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS16130 ^@ http://purl.uniprot.org/uniprot/R4X1L7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/758793:BRPE64_RS20255 ^@ http://purl.uniprot.org/uniprot/R4X326 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/758793:BRPE64_RS20290 ^@ http://purl.uniprot.org/uniprot/R4WN68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS04850 ^@ http://purl.uniprot.org/uniprot/R4WPI2 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/758793:BRPE64_RS20020 ^@ http://purl.uniprot.org/uniprot/R4WN18 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS12300 ^@ http://purl.uniprot.org/uniprot/R4WJ12 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/758793:BRPE64_RS03860 ^@ http://purl.uniprot.org/uniprot/R4WX70 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS21540 ^@ http://purl.uniprot.org/uniprot/R4WNS2 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/758793:BRPE64_RS20035 ^@ http://purl.uniprot.org/uniprot/R4WMT4 ^@ Function|||Similarity ^@ Belongs to the folylpolyglutamate synthase family.|||Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. http://togogenome.org/gene/758793:BRPE64_RS30535 ^@ http://purl.uniprot.org/uniprot/R4WUE0 ^@ Function ^@ E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/758793:BRPE64_RS23910 ^@ http://purl.uniprot.org/uniprot/R4WQE5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS18810 ^@ http://purl.uniprot.org/uniprot/R4X2I7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS14230 ^@ http://purl.uniprot.org/uniprot/R4WJN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS24560 ^@ http://purl.uniprot.org/uniprot/R4WZ44 ^@ Function|||Similarity ^@ Belongs to the nucleoside phosphorylase PpnP family.|||Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. http://togogenome.org/gene/758793:BRPE64_RS00150 ^@ http://purl.uniprot.org/uniprot/R4WES4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS05100 ^@ http://purl.uniprot.org/uniprot/R4WGE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS00105 ^@ http://purl.uniprot.org/uniprot/R4WSD1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS08415 ^@ http://purl.uniprot.org/uniprot/R4WHA8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/758793:BRPE64_RS07075 ^@ http://purl.uniprot.org/uniprot/R4WGZ6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS14670 ^@ http://purl.uniprot.org/uniprot/R4WUY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FTR family.|||Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/758793:BRPE64_RS13200 ^@ http://purl.uniprot.org/uniprot/R4WJ63 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/758793:BRPE64_RS20490 ^@ http://purl.uniprot.org/uniprot/R4X344 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lipase chaperone family.|||Cell inner membrane|||May be involved in the folding of the extracellular lipase during its passage through the periplasm. http://togogenome.org/gene/758793:BRPE64_RS00225 ^@ http://purl.uniprot.org/uniprot/R4WEL4 ^@ Similarity ^@ Belongs to the MreC family. http://togogenome.org/gene/758793:BRPE64_RS12485 ^@ http://purl.uniprot.org/uniprot/R4X0D6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/758793:BRPE64_RS24065 ^@ http://purl.uniprot.org/uniprot/R4WQG5 ^@ Similarity ^@ Belongs to the AAA ATPase family.|||In the C-terminal section; belongs to the peptidase M41 family. http://togogenome.org/gene/758793:BRPE64_RS27625 ^@ http://purl.uniprot.org/uniprot/R4X087 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/758793:BRPE64_RS11090 ^@ http://purl.uniprot.org/uniprot/R4WSX0 ^@ Domain|||Function|||Subcellular Location Annotation ^@ Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.|||Periplasm|||The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition. http://togogenome.org/gene/758793:BRPE64_RS27265 ^@ http://purl.uniprot.org/uniprot/R4X4P9 ^@ Function|||Similarity ^@ Belongs to the SsuD family.|||Catalyzes the desulfonation of aliphatic sulfonates. http://togogenome.org/gene/758793:BRPE64_RS28500 ^@ http://purl.uniprot.org/uniprot/R4X0P0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS29100 ^@ http://purl.uniprot.org/uniprot/R4WTG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS13290 ^@ http://purl.uniprot.org/uniprot/R4WYT6 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/758793:BRPE64_RS12205 ^@ http://purl.uniprot.org/uniprot/R4WIT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS08380 ^@ http://purl.uniprot.org/uniprot/R4WRD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/758793:BRPE64_RS12200 ^@ http://purl.uniprot.org/uniprot/R4X0A3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB). http://togogenome.org/gene/758793:BRPE64_RS17670 ^@ http://purl.uniprot.org/uniprot/R4WLQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/758793:BRPE64_RS12400 ^@ http://purl.uniprot.org/uniprot/R4WJ24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/758793:BRPE64_RS12585 ^@ http://purl.uniprot.org/uniprot/R4WTQ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS11430 ^@ http://purl.uniprot.org/uniprot/R4WIK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS25085 ^@ http://purl.uniprot.org/uniprot/R4X2Z7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS10840 ^@ http://purl.uniprot.org/uniprot/R4WIB2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS16355 ^@ http://purl.uniprot.org/uniprot/R4WZX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS03900 ^@ http://purl.uniprot.org/uniprot/R4WUG5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiD family.|||Binds 1 prenylated FMN (prenyl-FMN) per subunit.|||Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.|||Cell membrane|||Homohexamer. http://togogenome.org/gene/758793:BRPE64_RS15300 ^@ http://purl.uniprot.org/uniprot/R4X1D3 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/758793:BRPE64_RS13010 ^@ http://purl.uniprot.org/uniprot/R4WJ98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS30825 ^@ http://purl.uniprot.org/uniprot/R4X1L2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS23515 ^@ http://purl.uniprot.org/uniprot/R4X2E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS05880 ^@ http://purl.uniprot.org/uniprot/R4WQ02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS12505 ^@ http://purl.uniprot.org/uniprot/R4WYJ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/758793:BRPE64_RS03380 ^@ http://purl.uniprot.org/uniprot/R4WNK3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/758793:BRPE64_RS15380 ^@ http://purl.uniprot.org/uniprot/R4WZJ9 ^@ PTM ^@ Binds 2 heme c groups covalently per subunit. http://togogenome.org/gene/758793:BRPE64_RS11605 ^@ http://purl.uniprot.org/uniprot/R4WT65 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS02835 ^@ http://purl.uniprot.org/uniprot/R4WFP0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS03415 ^@ http://purl.uniprot.org/uniprot/R4WFL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS04055 ^@ http://purl.uniprot.org/uniprot/R4WFS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS08010 ^@ http://purl.uniprot.org/uniprot/R4WH66 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/758793:BRPE64_RS14970 ^@ http://purl.uniprot.org/uniprot/R4X1A0 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/758793:BRPE64_RS21960 ^@ http://purl.uniprot.org/uniprot/R4WY83 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS03385 ^@ http://purl.uniprot.org/uniprot/R4WU86 ^@ Function|||Similarity|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ. http://togogenome.org/gene/758793:BRPE64_RS00945 ^@ http://purl.uniprot.org/uniprot/R4WVM2 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/758793:BRPE64_RS19385 ^@ http://purl.uniprot.org/uniprot/R4WMS1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS21600 ^@ http://purl.uniprot.org/uniprot/R4X1S0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS22140 ^@ http://purl.uniprot.org/uniprot/R4X3H8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS02825 ^@ http://purl.uniprot.org/uniprot/R4WWT3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/758793:BRPE64_RS08985 ^@ http://purl.uniprot.org/uniprot/R4WX92 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/758793:BRPE64_RS12090 ^@ http://purl.uniprot.org/uniprot/R4WTI6 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/758793:BRPE64_RS22455 ^@ http://purl.uniprot.org/uniprot/R4X3K4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS20075 ^@ http://purl.uniprot.org/uniprot/R4X151 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS13145 ^@ http://purl.uniprot.org/uniprot/R4X0K6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/758793:BRPE64_RS11610 ^@ http://purl.uniprot.org/uniprot/R4WY80 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS24445 ^@ http://purl.uniprot.org/uniprot/R4WQM6 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/758793:BRPE64_RS00265 ^@ http://purl.uniprot.org/uniprot/R4WSG1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS29125 ^@ http://purl.uniprot.org/uniprot/R4WTH3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS05810 ^@ http://purl.uniprot.org/uniprot/R4WVJ9 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/758793:BRPE64_RS08870 ^@ http://purl.uniprot.org/uniprot/R4WRM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS25700 ^@ http://purl.uniprot.org/uniprot/R4WZJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS19325 ^@ http://purl.uniprot.org/uniprot/R4WXB6 ^@ Cofactor ^@ Binds 4 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/758793:BRPE64_RS07250 ^@ http://purl.uniprot.org/uniprot/R4WGZ8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS04550 ^@ http://purl.uniprot.org/uniprot/R4WXF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS02660 ^@ http://purl.uniprot.org/uniprot/R4WN75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAE transporter (TC 2.A.81) family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS17320 ^@ http://purl.uniprot.org/uniprot/R4WLK3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/758793:BRPE64_RS30870 ^@ http://purl.uniprot.org/uniprot/A0A060PGS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS10120 ^@ http://purl.uniprot.org/uniprot/R4WXP8 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/758793:BRPE64_RS11345 ^@ http://purl.uniprot.org/uniprot/R4WII6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS20085 ^@ http://purl.uniprot.org/uniprot/R4WN30 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/758793:BRPE64_RS13655 ^@ http://purl.uniprot.org/uniprot/R4WJK6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/758793:BRPE64_RS17655 ^@ http://purl.uniprot.org/uniprot/R4X0C9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS10445 ^@ http://purl.uniprot.org/uniprot/R4WZM3 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/758793:BRPE64_RS07460 ^@ http://purl.uniprot.org/uniprot/R4WQX2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/758793:BRPE64_RS18670 ^@ http://purl.uniprot.org/uniprot/R4WM07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS12675 ^@ http://purl.uniprot.org/uniprot/R4WJ54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS00850 ^@ http://purl.uniprot.org/uniprot/R4WSR9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS25265 ^@ http://purl.uniprot.org/uniprot/R4WZB6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS12325 ^@ http://purl.uniprot.org/uniprot/R4WTL7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/758793:BRPE64_RS21160 ^@ http://purl.uniprot.org/uniprot/R4WXY6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS25170 ^@ http://purl.uniprot.org/uniprot/R4WR20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS20400 ^@ http://purl.uniprot.org/uniprot/R4X337 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS09300 ^@ http://purl.uniprot.org/uniprot/R4WXE2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS01795 ^@ http://purl.uniprot.org/uniprot/R4WT96 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/758793:BRPE64_RS09815 ^@ http://purl.uniprot.org/uniprot/R4WHX5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/758793:BRPE64_RS25315 ^@ http://purl.uniprot.org/uniprot/R4WZC5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS12500 ^@ http://purl.uniprot.org/uniprot/R4WTP4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/758793:BRPE64_RS13310 ^@ http://purl.uniprot.org/uniprot/R4WU41 ^@ Function|||Similarity ^@ In the C-terminal section; belongs to the aldehyde dehydrogenase family.|||In the N-terminal section; belongs to the proline dehydrogenase family.|||Oxidizes proline to glutamate for use as a carbon and nitrogen source. http://togogenome.org/gene/758793:BRPE64_RS28070 ^@ http://purl.uniprot.org/uniprot/R4X4W3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS19565 ^@ http://purl.uniprot.org/uniprot/R4WMJ6 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS01570 ^@ http://purl.uniprot.org/uniprot/R4WEZ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/758793:BRPE64_RS12985 ^@ http://purl.uniprot.org/uniprot/R4WJ95 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/758793:BRPE64_RS23120 ^@ http://purl.uniprot.org/uniprot/R4WYK8 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/758793:BRPE64_RS04615 ^@ http://purl.uniprot.org/uniprot/R4WXG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS07490 ^@ http://purl.uniprot.org/uniprot/R4WWJ6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS00520 ^@ http://purl.uniprot.org/uniprot/R4WM00 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/758793:BRPE64_RS28380 ^@ http://purl.uniprot.org/uniprot/R4X0K9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS20545 ^@ http://purl.uniprot.org/uniprot/R4WN20 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS17520 ^@ http://purl.uniprot.org/uniprot/R4WWC8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS25975 ^@ http://purl.uniprot.org/uniprot/R4X388 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS07255 ^@ http://purl.uniprot.org/uniprot/R4WH29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS00230 ^@ http://purl.uniprot.org/uniprot/R4WET1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/758793:BRPE64_RS21645 ^@ http://purl.uniprot.org/uniprot/R4WY55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS06230 ^@ http://purl.uniprot.org/uniprot/R4WGJ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/758793:BRPE64_RS16275 ^@ http://purl.uniprot.org/uniprot/R4WZV5 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/758793:BRPE64_RS23715 ^@ http://purl.uniprot.org/uniprot/R4WQ04 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS25300 ^@ http://purl.uniprot.org/uniprot/R4X482 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS14960 ^@ http://purl.uniprot.org/uniprot/R4WK90 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/758793:BRPE64_RS18645 ^@ http://purl.uniprot.org/uniprot/R4WM03 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS09515 ^@ http://purl.uniprot.org/uniprot/R4WXI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RseB family.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS03150 ^@ http://purl.uniprot.org/uniprot/R4WNG4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/758793:BRPE64_RS21660 ^@ http://purl.uniprot.org/uniprot/R4WNU0 ^@ Caution|||Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS00615 ^@ http://purl.uniprot.org/uniprot/R4WSM5 ^@ Function ^@ Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY. http://togogenome.org/gene/758793:BRPE64_RS29745 ^@ http://purl.uniprot.org/uniprot/R4WTQ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS30135 ^@ http://purl.uniprot.org/uniprot/R4X5C6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS09030 ^@ http://purl.uniprot.org/uniprot/R4WX99 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/758793:BRPE64_RS17565 ^@ http://purl.uniprot.org/uniprot/R4WLE6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS09880 ^@ http://purl.uniprot.org/uniprot/R4WZF7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS30295 ^@ http://purl.uniprot.org/uniprot/R4X4C4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS26205 ^@ http://purl.uniprot.org/uniprot/R4X3B3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS15870 ^@ http://purl.uniprot.org/uniprot/R4WZQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS19220 ^@ http://purl.uniprot.org/uniprot/R4WMP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic sulfate-binding protein family.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS22695 ^@ http://purl.uniprot.org/uniprot/R4WPI9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS07735 ^@ http://purl.uniprot.org/uniprot/R4WR23 ^@ Similarity ^@ In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/758793:BRPE64_RS10790 ^@ http://purl.uniprot.org/uniprot/R4WIA5 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/758793:BRPE64_RS26270 ^@ http://purl.uniprot.org/uniprot/R4WRV1 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. http://togogenome.org/gene/758793:BRPE64_RS21115 ^@ http://purl.uniprot.org/uniprot/R4WNF6 ^@ Function|||Similarity ^@ Belongs to the ClpA/ClpB family.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK. http://togogenome.org/gene/758793:BRPE64_RS04890 ^@ http://purl.uniprot.org/uniprot/R4WPJ0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS12420 ^@ http://purl.uniprot.org/uniprot/R4WIV8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/758793:BRPE64_RS28565 ^@ http://purl.uniprot.org/uniprot/R4WT84 ^@ Similarity ^@ Belongs to the class-C beta-lactamase family. http://togogenome.org/gene/758793:BRPE64_RS21775 ^@ http://purl.uniprot.org/uniprot/R4X1T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS21335 ^@ http://purl.uniprot.org/uniprot/R4WY08 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS12270 ^@ http://purl.uniprot.org/uniprot/R4WYG6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MsrQ family.|||Binds 1 FMN per subunit.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Cell membrane|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Membrane|||Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain. http://togogenome.org/gene/758793:BRPE64_RS11185 ^@ http://purl.uniprot.org/uniprot/R4WSY9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS16565 ^@ http://purl.uniprot.org/uniprot/R4X004 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Member of a two-component regulatory system. http://togogenome.org/gene/758793:BRPE64_RS11140 ^@ http://purl.uniprot.org/uniprot/R4WY19 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HemJ family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS11085 ^@ http://purl.uniprot.org/uniprot/R4WIF0 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||The active site is located at the dimer interface. http://togogenome.org/gene/758793:BRPE64_RS11645 ^@ http://purl.uniprot.org/uniprot/R4WII3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Membrane|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/758793:BRPE64_RS16860 ^@ http://purl.uniprot.org/uniprot/R4WLD6 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/758793:BRPE64_RS05565 ^@ http://purl.uniprot.org/uniprot/R4WGA8 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/758793:BRPE64_RS00215 ^@ http://purl.uniprot.org/uniprot/R4WSF2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. MrdA subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall.|||Cell inner membrane http://togogenome.org/gene/758793:BRPE64_RS08750 ^@ http://purl.uniprot.org/uniprot/R4WZ08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS16165 ^@ http://purl.uniprot.org/uniprot/R4WKM7 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS08400 ^@ http://purl.uniprot.org/uniprot/R4WRE0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/758793:BRPE64_RS22490 ^@ http://purl.uniprot.org/uniprot/R4WYD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS20065 ^@ http://purl.uniprot.org/uniprot/R4WN26 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS09280 ^@ http://purl.uniprot.org/uniprot/R4WZ80 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/758793:BRPE64_RS15225 ^@ http://purl.uniprot.org/uniprot/R4WKD1 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/758793:BRPE64_RS13110 ^@ http://purl.uniprot.org/uniprot/R4WU04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/758793:BRPE64_RS10850 ^@ http://purl.uniprot.org/uniprot/R4WXY5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably interacts with PlsX. http://togogenome.org/gene/758793:BRPE64_RS11485 ^@ http://purl.uniprot.org/uniprot/R4X002 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS07985 ^@ http://purl.uniprot.org/uniprot/R4WWU2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS02140 ^@ http://purl.uniprot.org/uniprot/R4WMW3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS01800 ^@ http://purl.uniprot.org/uniprot/R4WF22 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/758793:BRPE64_RS10950 ^@ http://purl.uniprot.org/uniprot/R4WZS9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the tryptophan 2,3-dioxygenase family.|||Binds 1 heme group per subunit.|||Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.|||Homotetramer. http://togogenome.org/gene/758793:BRPE64_RS02250 ^@ http://purl.uniprot.org/uniprot/R4WF90 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/758793:BRPE64_RS15065 ^@ http://purl.uniprot.org/uniprot/R4X1A9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS00845 ^@ http://purl.uniprot.org/uniprot/R4WM60 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/758793:BRPE64_RS03940 ^@ http://purl.uniprot.org/uniprot/R4WFZ4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS10325 ^@ http://purl.uniprot.org/uniprot/R4WI35 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS04845 ^@ http://purl.uniprot.org/uniprot/R4WGB3 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. http://togogenome.org/gene/758793:BRPE64_RS20520 ^@ http://purl.uniprot.org/uniprot/R4WN17 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/758793:BRPE64_RS04025 ^@ http://purl.uniprot.org/uniprot/R4WX85 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/758793:BRPE64_RS07695 ^@ http://purl.uniprot.org/uniprot/R4WYN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/758793:BRPE64_RS10465 ^@ http://purl.uniprot.org/uniprot/R4WXT8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS06870 ^@ http://purl.uniprot.org/uniprot/R4WQJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS06335 ^@ http://purl.uniprot.org/uniprot/R4WGS1 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/758793:BRPE64_RS24880 ^@ http://purl.uniprot.org/uniprot/R4WQK6 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system. http://togogenome.org/gene/758793:BRPE64_RS26665 ^@ http://purl.uniprot.org/uniprot/R4X4J3 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/758793:BRPE64_RS27160 ^@ http://purl.uniprot.org/uniprot/R4WS93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS28820 ^@ http://purl.uniprot.org/uniprot/R4WT82 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/758793:BRPE64_RS23405 ^@ http://purl.uniprot.org/uniprot/R4X3S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS00950 ^@ http://purl.uniprot.org/uniprot/R4WER6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/758793:BRPE64_RS31460 ^@ http://purl.uniprot.org/uniprot/A0A060PJL7 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/758793:BRPE64_RS11515 ^@ http://purl.uniprot.org/uniprot/R4X006 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS01660 ^@ http://purl.uniprot.org/uniprot/R4WMJ9 ^@ Similarity ^@ Belongs to the transcriptional regulatory Fis family. http://togogenome.org/gene/758793:BRPE64_RS12050 ^@ http://purl.uniprot.org/uniprot/R4WYE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS18785 ^@ http://purl.uniprot.org/uniprot/R4X2I5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. http://togogenome.org/gene/758793:BRPE64_RS01065 ^@ http://purl.uniprot.org/uniprot/R4WVP5 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/758793:BRPE64_RS27020 ^@ http://purl.uniprot.org/uniprot/R4WS65 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS30865 ^@ http://purl.uniprot.org/uniprot/A0A060PK96 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/758793:BRPE64_RS09900 ^@ http://purl.uniprot.org/uniprot/R4WXL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS30045 ^@ http://purl.uniprot.org/uniprot/R4X163 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/758793:BRPE64_RS10190 ^@ http://purl.uniprot.org/uniprot/R4WSE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreD family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/758793:BRPE64_RS13360 ^@ http://purl.uniprot.org/uniprot/R4WYU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/758793:BRPE64_RS31090 ^@ http://purl.uniprot.org/uniprot/A0A060PRF6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS15930 ^@ http://purl.uniprot.org/uniprot/R4WKS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS28490 ^@ http://purl.uniprot.org/uniprot/R4WT34 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS13650 ^@ http://purl.uniprot.org/uniprot/R4WJE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS07220 ^@ http://purl.uniprot.org/uniprot/R4WWF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS09345 ^@ http://purl.uniprot.org/uniprot/R4WRY4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Binds 2 Zn(2+) ions per subunit.|||Monomer.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/758793:BRPE64_RS10965 ^@ http://purl.uniprot.org/uniprot/R4WSU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS28695 ^@ http://purl.uniprot.org/uniprot/R4X514 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS06580 ^@ http://purl.uniprot.org/uniprot/R4WGN6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS31420 ^@ http://purl.uniprot.org/uniprot/A0A060PR26 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS29055 ^@ http://purl.uniprot.org/uniprot/R4X0U4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS30740 ^@ http://purl.uniprot.org/uniprot/R4X1J9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS26265 ^@ http://purl.uniprot.org/uniprot/R4WRL8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS05485 ^@ http://purl.uniprot.org/uniprot/R4WVD8 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/758793:BRPE64_RS02505 ^@ http://purl.uniprot.org/uniprot/R4WFK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS27025 ^@ http://purl.uniprot.org/uniprot/R4X019 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS21780 ^@ http://purl.uniprot.org/uniprot/R4X3F0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS09855 ^@ http://purl.uniprot.org/uniprot/R4WZF4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/758793:BRPE64_RS16095 ^@ http://purl.uniprot.org/uniprot/R4WKL2 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS09325 ^@ http://purl.uniprot.org/uniprot/R4WXE6 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS28935 ^@ http://purl.uniprot.org/uniprot/R4X527 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS21225 ^@ http://purl.uniprot.org/uniprot/R4WNI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS24185 ^@ http://purl.uniprot.org/uniprot/R4WQI1 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/758793:BRPE64_RS06850 ^@ http://purl.uniprot.org/uniprot/R4WW41 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/758793:BRPE64_RS31495 ^@ http://purl.uniprot.org/uniprot/A0A060PH70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS20050 ^@ http://purl.uniprot.org/uniprot/R4X148 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/758793:BRPE64_RS12385 ^@ http://purl.uniprot.org/uniprot/R4WYI2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/758793:BRPE64_RS01665 ^@ http://purl.uniprot.org/uniprot/R4WT63 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusB subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/758793:BRPE64_RS02800 ^@ http://purl.uniprot.org/uniprot/R4WTY2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS06200 ^@ http://purl.uniprot.org/uniprot/R4WY22 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS13210 ^@ http://purl.uniprot.org/uniprot/R4WU23 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/758793:BRPE64_RS11865 ^@ http://purl.uniprot.org/uniprot/R4WIS9 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS03175 ^@ http://purl.uniprot.org/uniprot/R4WFS1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS24155 ^@ http://purl.uniprot.org/uniprot/R4WQ80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS07995 ^@ http://purl.uniprot.org/uniprot/R4WR72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS29495 ^@ http://purl.uniprot.org/uniprot/R4X458 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS11265 ^@ http://purl.uniprot.org/uniprot/R4WZX2 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/758793:BRPE64_RS10330 ^@ http://purl.uniprot.org/uniprot/R4WSH3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS15960 ^@ http://purl.uniprot.org/uniprot/R4WVK7 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS03400 ^@ http://purl.uniprot.org/uniprot/R4WNK8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS25575 ^@ http://purl.uniprot.org/uniprot/R4WR15 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/758793:BRPE64_RS11270 ^@ http://purl.uniprot.org/uniprot/R4WIC2 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/758793:BRPE64_RS03245 ^@ http://purl.uniprot.org/uniprot/R4WFS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS21735 ^@ http://purl.uniprot.org/uniprot/R4WP20 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/758793:BRPE64_RS02680 ^@ http://purl.uniprot.org/uniprot/R4WFM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS11535 ^@ http://purl.uniprot.org/uniprot/R4WY69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS17435 ^@ http://purl.uniprot.org/uniprot/R4WLC9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/758793:BRPE64_RS15440 ^@ http://purl.uniprot.org/uniprot/R4WK86 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS05770 ^@ http://purl.uniprot.org/uniprot/R4WXX3 ^@ Similarity ^@ Belongs to the skp family. http://togogenome.org/gene/758793:BRPE64_RS27380 ^@ http://purl.uniprot.org/uniprot/R4X3L5 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/758793:BRPE64_RS13115 ^@ http://purl.uniprot.org/uniprot/R4WYR5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/758793:BRPE64_RS17385 ^@ http://purl.uniprot.org/uniprot/R4WLC2 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/758793:BRPE64_RS23190 ^@ http://purl.uniprot.org/uniprot/R4WPL1 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/758793:BRPE64_RS10805 ^@ http://purl.uniprot.org/uniprot/R4WZR2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS06615 ^@ http://purl.uniprot.org/uniprot/R4WW02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YciB family.|||Cell inner membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. http://togogenome.org/gene/758793:BRPE64_RS21295 ^@ http://purl.uniprot.org/uniprot/R4X3A5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS02235 ^@ http://purl.uniprot.org/uniprot/R4WMY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS15155 ^@ http://purl.uniprot.org/uniprot/R4WV50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS02025 ^@ http://purl.uniprot.org/uniprot/R4WTF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS04290 ^@ http://purl.uniprot.org/uniprot/R4WXB7 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS27610 ^@ http://purl.uniprot.org/uniprot/R4X4S6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/758793:BRPE64_RS29345 ^@ http://purl.uniprot.org/uniprot/R4X446 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/758793:BRPE64_RS27415 ^@ http://purl.uniprot.org/uniprot/R4WS81 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/758793:BRPE64_RS01775 ^@ http://purl.uniprot.org/uniprot/R4WT91 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/758793:BRPE64_RS18300 ^@ http://purl.uniprot.org/uniprot/R4WWT5 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/758793:BRPE64_RS02565 ^@ http://purl.uniprot.org/uniprot/R4WTU1 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS19530 ^@ http://purl.uniprot.org/uniprot/R4X0Z8 ^@ Similarity ^@ Belongs to the bacterial phospholipase C family. http://togogenome.org/gene/758793:BRPE64_RS03115 ^@ http://purl.uniprot.org/uniprot/R4WFH7 ^@ Function ^@ Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/758793:BRPE64_RS29240 ^@ http://purl.uniprot.org/uniprot/R4WTF8 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/758793:BRPE64_RS03950 ^@ http://purl.uniprot.org/uniprot/R4WUH3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS18460 ^@ http://purl.uniprot.org/uniprot/R4X0L7 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/758793:BRPE64_RS08700 ^@ http://purl.uniprot.org/uniprot/R4WZ01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS01645 ^@ http://purl.uniprot.org/uniprot/R4WW03 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/758793:BRPE64_RS22405 ^@ http://purl.uniprot.org/uniprot/R4X3K0 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/758793:BRPE64_RS23830 ^@ http://purl.uniprot.org/uniprot/R4WQ32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS30315 ^@ http://purl.uniprot.org/uniprot/R4X1A6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS16175 ^@ http://purl.uniprot.org/uniprot/R4WZU0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS06330 ^@ http://purl.uniprot.org/uniprot/R4WGK2 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/758793:BRPE64_RS29535 ^@ http://purl.uniprot.org/uniprot/R4WTP7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS09635 ^@ http://purl.uniprot.org/uniprot/R4WXJ1 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/758793:BRPE64_RS29330 ^@ http://purl.uniprot.org/uniprot/R4WTH6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/758793:BRPE64_RS02745 ^@ http://purl.uniprot.org/uniprot/R4WN92 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/758793:BRPE64_RS23070 ^@ http://purl.uniprot.org/uniprot/R4X3Q0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS11360 ^@ http://purl.uniprot.org/uniprot/R4WZY4 ^@ Function|||Similarity ^@ Belongs to the MurCDEF family. Mpl subfamily.|||Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate. http://togogenome.org/gene/758793:BRPE64_RS31360 ^@ http://purl.uniprot.org/uniprot/A0A060PJI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS25955 ^@ http://purl.uniprot.org/uniprot/R4WRC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS05305 ^@ http://purl.uniprot.org/uniprot/R4WPQ8 ^@ Similarity ^@ Belongs to the WrbA family. http://togogenome.org/gene/758793:BRPE64_RS00260 ^@ http://purl.uniprot.org/uniprot/R4WLW0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/758793:BRPE64_RS23635 ^@ http://purl.uniprot.org/uniprot/R4X3U6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS15245 ^@ http://purl.uniprot.org/uniprot/R4WKD4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/758793:BRPE64_RS26385 ^@ http://purl.uniprot.org/uniprot/R4WRX0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS09540 ^@ http://purl.uniprot.org/uniprot/R4WXI3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS29365 ^@ http://purl.uniprot.org/uniprot/R4X0X8 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS28225 ^@ http://purl.uniprot.org/uniprot/R4WSY7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/758793:BRPE64_RS09250 ^@ http://purl.uniprot.org/uniprot/R4WXD3 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/758793:BRPE64_RS30200 ^@ http://purl.uniprot.org/uniprot/R4X5D2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/758793:BRPE64_RS03025 ^@ http://purl.uniprot.org/uniprot/R4WNE1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/758793:BRPE64_RS17365 ^@ http://purl.uniprot.org/uniprot/R4WLB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS19640 ^@ http://purl.uniprot.org/uniprot/R4WMV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS06825 ^@ http://purl.uniprot.org/uniprot/R4WYB4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS25185 ^@ http://purl.uniprot.org/uniprot/R4X471 ^@ Similarity ^@ Belongs to the proline racemase family. http://togogenome.org/gene/758793:BRPE64_RS20155 ^@ http://purl.uniprot.org/uniprot/R4X319 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/758793:BRPE64_RS19070 ^@ http://purl.uniprot.org/uniprot/R4X2P8 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/758793:BRPE64_RS17355 ^@ http://purl.uniprot.org/uniprot/R4X096 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the selenophosphate synthase 1 family. Class I subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Homodimer.|||Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/758793:BRPE64_RS11375 ^@ http://purl.uniprot.org/uniprot/R4WZY7 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/758793:BRPE64_RS05245 ^@ http://purl.uniprot.org/uniprot/R4WG80 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.|||Binds 1 zinc ion per subunit.|||Transforms N(2)-succinylglutamate into succinate and glutamate. http://togogenome.org/gene/758793:BRPE64_RS24685 ^@ http://purl.uniprot.org/uniprot/R4WZ57 ^@ Similarity ^@ Belongs to the bacterial phospholipase C family. http://togogenome.org/gene/758793:BRPE64_RS18850 ^@ http://purl.uniprot.org/uniprot/R4X0Q7 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS24935 ^@ http://purl.uniprot.org/uniprot/R4WQV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS22220 ^@ http://purl.uniprot.org/uniprot/R4X1X9 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/758793:BRPE64_RS08855 ^@ http://purl.uniprot.org/uniprot/R4WZ22 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/758793:BRPE64_RS20385 ^@ http://purl.uniprot.org/uniprot/R4WN86 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/758793:BRPE64_RS25075 ^@ http://purl.uniprot.org/uniprot/R4WQZ5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS02085 ^@ http://purl.uniprot.org/uniprot/R4WFE2 ^@ Cofactor ^@ Binds 3 heme c groups covalently per subunit. http://togogenome.org/gene/758793:BRPE64_RS05605 ^@ http://purl.uniprot.org/uniprot/R4WXV3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS03295 ^@ http://purl.uniprot.org/uniprot/R4WFT2 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/758793:BRPE64_RS01780 ^@ http://purl.uniprot.org/uniprot/R4WW25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/758793:BRPE64_RS11080 ^@ http://purl.uniprot.org/uniprot/R4WI89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/758793:BRPE64_RS07225 ^@ http://purl.uniprot.org/uniprot/R4WYI6 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/758793:BRPE64_RS03260 ^@ http://purl.uniprot.org/uniprot/R4WX06 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/758793:BRPE64_RS22785 ^@ http://purl.uniprot.org/uniprot/R4WPL2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS24985 ^@ http://purl.uniprot.org/uniprot/R4WZ86 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family.|||Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/758793:BRPE64_RS25365 ^@ http://purl.uniprot.org/uniprot/R4X329 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/758793:BRPE64_RS03340 ^@ http://purl.uniprot.org/uniprot/R4WFK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS14440 ^@ http://purl.uniprot.org/uniprot/R4WZA2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS12395 ^@ http://purl.uniprot.org/uniprot/R4WIV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/758793:BRPE64_RS13250 ^@ http://purl.uniprot.org/uniprot/R4WJ70 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. UvrD subfamily.|||Homodimer.|||Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. http://togogenome.org/gene/758793:BRPE64_RS01000 ^@ http://purl.uniprot.org/uniprot/R4WES3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COX11/CtaG family.|||Cell inner membrane|||Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I. http://togogenome.org/gene/758793:BRPE64_RS19785 ^@ http://purl.uniprot.org/uniprot/R4WMN3 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/758793:BRPE64_RS01590 ^@ http://purl.uniprot.org/uniprot/R4WVZ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS06450 ^@ http://purl.uniprot.org/uniprot/R4WY56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/758793:BRPE64_RS28655 ^@ http://purl.uniprot.org/uniprot/R4WTA0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS15775 ^@ http://purl.uniprot.org/uniprot/R4WVH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.|||Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.|||Homotetramer; dimer of dimers.|||Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate. http://togogenome.org/gene/758793:BRPE64_RS09285 ^@ http://purl.uniprot.org/uniprot/R4WHL3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/758793:BRPE64_RS09985 ^@ http://purl.uniprot.org/uniprot/R4WHZ1 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS01790 ^@ http://purl.uniprot.org/uniprot/R4WF94 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS26085 ^@ http://purl.uniprot.org/uniprot/R4X3A4 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/758793:BRPE64_RS08030 ^@ http://purl.uniprot.org/uniprot/R4WYS6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/758793:BRPE64_RS11800 ^@ http://purl.uniprot.org/uniprot/R4X036 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/758793:BRPE64_RS08585 ^@ http://purl.uniprot.org/uniprot/R4WX45 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/758793:BRPE64_RS18035 ^@ http://purl.uniprot.org/uniprot/R4X0H0 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS03795 ^@ http://purl.uniprot.org/uniprot/R4WFX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.|||Homodimer.|||Involved in phosphonate degradation. http://togogenome.org/gene/758793:BRPE64_RS09410 ^@ http://purl.uniprot.org/uniprot/R4WXF8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS27045 ^@ http://purl.uniprot.org/uniprot/R4WS70 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS28075 ^@ http://purl.uniprot.org/uniprot/R4WSQ3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS29645 ^@ http://purl.uniprot.org/uniprot/R4X585 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS01545 ^@ http://purl.uniprot.org/uniprot/R4WEZ0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/758793:BRPE64_RS05655 ^@ http://purl.uniprot.org/uniprot/R4WGC0 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.|||Methylates ribosomal protein uL3 on a specific glutamine residue. http://togogenome.org/gene/758793:BRPE64_RS12010 ^@ http://purl.uniprot.org/uniprot/R4WIR0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/758793:BRPE64_RS07715 ^@ http://purl.uniprot.org/uniprot/R4WWN7 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/758793:BRPE64_RS13720 ^@ http://purl.uniprot.org/uniprot/R4X0T2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS13030 ^@ http://purl.uniprot.org/uniprot/R4WJA2 ^@ Similarity ^@ Belongs to the type III secretion exporter family. http://togogenome.org/gene/758793:BRPE64_RS08615 ^@ http://purl.uniprot.org/uniprot/R4WHD1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/758793:BRPE64_RS10415 ^@ http://purl.uniprot.org/uniprot/R4WSJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS11590 ^@ http://purl.uniprot.org/uniprot/R4X015 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/758793:BRPE64_RS09500 ^@ http://purl.uniprot.org/uniprot/R4WZA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/758793:BRPE64_RS20355 ^@ http://purl.uniprot.org/uniprot/R4X334 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/758793:BRPE64_RS17260 ^@ http://purl.uniprot.org/uniprot/R4WW89 ^@ Similarity ^@ Belongs to the peptidase S45 family. http://togogenome.org/gene/758793:BRPE64_RS06530 ^@ http://purl.uniprot.org/uniprot/R4WQC3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/758793:BRPE64_RS24425 ^@ http://purl.uniprot.org/uniprot/R4WQM2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS14300 ^@ http://purl.uniprot.org/uniprot/R4WJV4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS00255 ^@ http://purl.uniprot.org/uniprot/R4WET3 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/758793:BRPE64_RS23350 ^@ http://purl.uniprot.org/uniprot/R4X3S4 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/758793:BRPE64_RS10310 ^@ http://purl.uniprot.org/uniprot/R4WXR9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS10250 ^@ http://purl.uniprot.org/uniprot/R4WZK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreF family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/758793:BRPE64_RS16885 ^@ http://purl.uniprot.org/uniprot/R4WLE1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS17725 ^@ http://purl.uniprot.org/uniprot/R4X0D5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS11750 ^@ http://purl.uniprot.org/uniprot/R4WY98 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.|||Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. http://togogenome.org/gene/758793:BRPE64_RS07380 ^@ http://purl.uniprot.org/uniprot/R4WH40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS04775 ^@ http://purl.uniprot.org/uniprot/R4WV14 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/758793:BRPE64_RS26185 ^@ http://purl.uniprot.org/uniprot/R4X4G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS05495 ^@ http://purl.uniprot.org/uniprot/R4WG99 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/758793:BRPE64_RS11015 ^@ http://purl.uniprot.org/uniprot/R4WSV7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS20955 ^@ http://purl.uniprot.org/uniprot/R4WNB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS09535 ^@ http://purl.uniprot.org/uniprot/R4WS42 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/758793:BRPE64_RS00895 ^@ http://purl.uniprot.org/uniprot/R4WVL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS07435 ^@ http://purl.uniprot.org/uniprot/R4WQW9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/758793:BRPE64_RS04670 ^@ http://purl.uniprot.org/uniprot/R4WG01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell inner membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/758793:BRPE64_RS31100 ^@ http://purl.uniprot.org/uniprot/A0A060PJD5 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/758793:BRPE64_RS15160 ^@ http://purl.uniprot.org/uniprot/R4WZH2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS16080 ^@ http://purl.uniprot.org/uniprot/R4WVM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS07785 ^@ http://purl.uniprot.org/uniprot/R4WWQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/758793:BRPE64_RS28230 ^@ http://purl.uniprot.org/uniprot/R4X0I4 ^@ Function ^@ Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. http://togogenome.org/gene/758793:BRPE64_RS18125 ^@ http://purl.uniprot.org/uniprot/R4X2B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS11490 ^@ http://purl.uniprot.org/uniprot/R4WIG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS20480 ^@ http://purl.uniprot.org/uniprot/R4WXN7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS09400 ^@ http://purl.uniprot.org/uniprot/R4WHR3 ^@ Function|||Similarity ^@ Belongs to the trehalose phosphatase family.|||Removes the phosphate from trehalose 6-phosphate to produce free trehalose. http://togogenome.org/gene/758793:BRPE64_RS21015 ^@ http://purl.uniprot.org/uniprot/R4X387 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS29270 ^@ http://purl.uniprot.org/uniprot/R4WTJ6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS14120 ^@ http://purl.uniprot.org/uniprot/R4WZ46 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/758793:BRPE64_RS09450 ^@ http://purl.uniprot.org/uniprot/R4WZ97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/758793:BRPE64_RS24280 ^@ http://purl.uniprot.org/uniprot/R4WZ14 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS28595 ^@ http://purl.uniprot.org/uniprot/R4X0Q0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS27245 ^@ http://purl.uniprot.org/uniprot/R4X3K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS01770 ^@ http://purl.uniprot.org/uniprot/R4WMM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS01555 ^@ http://purl.uniprot.org/uniprot/R4WMI3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS13825 ^@ http://purl.uniprot.org/uniprot/R4WUE9 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/758793:BRPE64_RS01695 ^@ http://purl.uniprot.org/uniprot/R4WF09 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/758793:BRPE64_RS04455 ^@ http://purl.uniprot.org/uniprot/R4WXE4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/758793:BRPE64_RS12855 ^@ http://purl.uniprot.org/uniprot/R4WYN4 ^@ Cofactor|||Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ A single active site specifically recognizes both ATP and CTP and is responsible for their addition.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.|||Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.|||Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.|||Magnesium is required for nucleotidyltransferase activity.|||Monomer. Can also form homodimers and oligomers.|||Nickel for phosphatase activity. http://togogenome.org/gene/758793:BRPE64_RS21730 ^@ http://purl.uniprot.org/uniprot/R4WNU8 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/758793:BRPE64_RS01975 ^@ http://purl.uniprot.org/uniprot/R4WTE0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/758793:BRPE64_RS29425 ^@ http://purl.uniprot.org/uniprot/R4X566 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS30875 ^@ http://purl.uniprot.org/uniprot/A0A060PJ90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS05750 ^@ http://purl.uniprot.org/uniprot/R4WGD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS11575 ^@ http://purl.uniprot.org/uniprot/R4WIM8 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/758793:BRPE64_RS01995 ^@ http://purl.uniprot.org/uniprot/R4WMS9 ^@ Function|||Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family.|||Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. http://togogenome.org/gene/758793:BRPE64_RS20570 ^@ http://purl.uniprot.org/uniprot/R4WNC9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family.|||Binds 2 potassium ions per subunit.|||Dimer of dimers.|||Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS02270 ^@ http://purl.uniprot.org/uniprot/R4WWI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS04555 ^@ http://purl.uniprot.org/uniprot/R4WFY5 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/758793:BRPE64_RS26655 ^@ http://purl.uniprot.org/uniprot/R4WZX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS20040 ^@ http://purl.uniprot.org/uniprot/R4WN22 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS29800 ^@ http://purl.uniprot.org/uniprot/R4WTW2 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/758793:BRPE64_RS05670 ^@ http://purl.uniprot.org/uniprot/R4WVH1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/758793:BRPE64_RS28080 ^@ http://purl.uniprot.org/uniprot/R4WSV6 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/758793:BRPE64_RS13125 ^@ http://purl.uniprot.org/uniprot/R4WJ53 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Secreted http://togogenome.org/gene/758793:BRPE64_RS14820 ^@ http://purl.uniprot.org/uniprot/R4WUZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MCH family.|||Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS04650 ^@ http://purl.uniprot.org/uniprot/R4WG71 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.|||Belongs to the RecD family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/758793:BRPE64_RS09760 ^@ http://purl.uniprot.org/uniprot/R4WS69 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/758793:BRPE64_RS10910 ^@ http://purl.uniprot.org/uniprot/R4WI61 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS13800 ^@ http://purl.uniprot.org/uniprot/R4WJN0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.|||Belongs to the SrkA/RdoA protein kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS22500 ^@ http://purl.uniprot.org/uniprot/R4X3K7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/758793:BRPE64_RS13840 ^@ http://purl.uniprot.org/uniprot/R4WJI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/758793:BRPE64_RS13090 ^@ http://purl.uniprot.org/uniprot/R4WYR2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS21740 ^@ http://purl.uniprot.org/uniprot/R4WY64 ^@ Function|||Similarity ^@ Belongs to the cyanase family.|||Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. http://togogenome.org/gene/758793:BRPE64_RS00140 ^@ http://purl.uniprot.org/uniprot/R4WSE0 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/758793:BRPE64_RS05325 ^@ http://purl.uniprot.org/uniprot/R4WGG4 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/758793:BRPE64_RS18520 ^@ http://purl.uniprot.org/uniprot/R4X2G1 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS06185 ^@ http://purl.uniprot.org/uniprot/R4WGI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS19015 ^@ http://purl.uniprot.org/uniprot/R4X0T0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS26600 ^@ http://purl.uniprot.org/uniprot/R4WRR8 ^@ Cofactor|||Similarity ^@ Belongs to the bacterial PQQ dehydrogenase family.|||Binds 1 Ca(2+) ion per subunit.|||Binds 1 PQQ group per subunit. http://togogenome.org/gene/758793:BRPE64_RS26115 ^@ http://purl.uniprot.org/uniprot/R4X4F8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS05465 ^@ http://purl.uniprot.org/uniprot/R4WXT6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS28660 ^@ http://purl.uniprot.org/uniprot/R4X0Q8 ^@ Similarity|||Subunit ^@ Belongs to the muconolactone Delta-isomerase family.|||Homodecamer. http://togogenome.org/gene/758793:BRPE64_RS07850 ^@ http://purl.uniprot.org/uniprot/R4WR45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS28520 ^@ http://purl.uniprot.org/uniprot/R4X3X6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS19305 ^@ http://purl.uniprot.org/uniprot/R4X0X7 ^@ Function ^@ Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. http://togogenome.org/gene/758793:BRPE64_RS02715 ^@ http://purl.uniprot.org/uniprot/R4WFM8 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/758793:BRPE64_RS11780 ^@ http://purl.uniprot.org/uniprot/R4WIK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/758793:BRPE64_RS00355 ^@ http://purl.uniprot.org/uniprot/R4WLX3 ^@ Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family. http://togogenome.org/gene/758793:BRPE64_RS11470 ^@ http://purl.uniprot.org/uniprot/R4WIL3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS11215 ^@ http://purl.uniprot.org/uniprot/R4WY25 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS04540 ^@ http://purl.uniprot.org/uniprot/R4WP79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Cytoplasm|||Homodimer.|||Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. http://togogenome.org/gene/758793:BRPE64_RS05025 ^@ http://purl.uniprot.org/uniprot/R4WG49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS24310 ^@ http://purl.uniprot.org/uniprot/R4X2P6 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/758793:BRPE64_RS28350 ^@ http://purl.uniprot.org/uniprot/R4WT11 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS20615 ^@ http://purl.uniprot.org/uniprot/R4WN34 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/758793:BRPE64_RS24250 ^@ http://purl.uniprot.org/uniprot/R4WQJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS14735 ^@ http://purl.uniprot.org/uniprot/R4X177 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RuBisCO small chain family.|||Heterohexadecamer of 8 large and 8 small subunits.|||RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.|||The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'. http://togogenome.org/gene/758793:BRPE64_RS10175 ^@ http://purl.uniprot.org/uniprot/R4WZJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS04985 ^@ http://purl.uniprot.org/uniprot/R4WPK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS31245 ^@ http://purl.uniprot.org/uniprot/A0A060PRJ4 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/758793:BRPE64_RS05055 ^@ http://purl.uniprot.org/uniprot/R4WGD6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS24865 ^@ http://purl.uniprot.org/uniprot/R4WZ77 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS17715 ^@ http://purl.uniprot.org/uniprot/R4WLQ8 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/758793:BRPE64_RS16740 ^@ http://purl.uniprot.org/uniprot/R4WW15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS02820 ^@ http://purl.uniprot.org/uniprot/R4WTY7 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/758793:BRPE64_RS18795 ^@ http://purl.uniprot.org/uniprot/R4WMB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/758793:BRPE64_RS15950 ^@ http://purl.uniprot.org/uniprot/R4WKI6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/758793:BRPE64_RS29090 ^@ http://purl.uniprot.org/uniprot/R4X535 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS14715 ^@ http://purl.uniprot.org/uniprot/R4WK53 ^@ Function ^@ Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). http://togogenome.org/gene/758793:BRPE64_RS13380 ^@ http://purl.uniprot.org/uniprot/R4WU55 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS11585 ^@ http://purl.uniprot.org/uniprot/R4WY76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/758793:BRPE64_RS13345 ^@ http://purl.uniprot.org/uniprot/R4WJ86 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/758793:BRPE64_RS08455 ^@ http://purl.uniprot.org/uniprot/R4WRE8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/758793:BRPE64_RS03370 ^@ http://purl.uniprot.org/uniprot/R4WFK3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/758793:BRPE64_RS02440 ^@ http://purl.uniprot.org/uniprot/R4WN40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS31145 ^@ http://purl.uniprot.org/uniprot/A0A060PJE5 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/758793:BRPE64_RS15135 ^@ http://purl.uniprot.org/uniprot/R4WV46 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/758793:BRPE64_RS04325 ^@ http://purl.uniprot.org/uniprot/R4WUN9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiC family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. http://togogenome.org/gene/758793:BRPE64_RS11395 ^@ http://purl.uniprot.org/uniprot/R4WZZ0 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/758793:BRPE64_RS09860 ^@ http://purl.uniprot.org/uniprot/R4WHT3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS19200 ^@ http://purl.uniprot.org/uniprot/R4WXA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS31110 ^@ http://purl.uniprot.org/uniprot/A0A060PRG2 ^@ Function|||Similarity ^@ Belongs to the nitrile hydratase subunit beta family.|||NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. http://togogenome.org/gene/758793:BRPE64_RS07585 ^@ http://purl.uniprot.org/uniprot/R4WQZ7 ^@ Similarity ^@ Belongs to the YfgM family. http://togogenome.org/gene/758793:BRPE64_RS07700 ^@ http://purl.uniprot.org/uniprot/R4WH28 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/758793:BRPE64_RS16045 ^@ http://purl.uniprot.org/uniprot/R4X1K5 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/758793:BRPE64_RS13135 ^@ http://purl.uniprot.org/uniprot/R4WU08 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.|||Bacterial flagellum basal body|||Belongs to the YcgR family.|||Monomer. Interacts with the flagellar basal bodies. http://togogenome.org/gene/758793:BRPE64_RS13075 ^@ http://purl.uniprot.org/uniprot/R4WJ46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS29435 ^@ http://purl.uniprot.org/uniprot/R4WTM5 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. http://togogenome.org/gene/758793:BRPE64_RS03130 ^@ http://purl.uniprot.org/uniprot/R4WU42 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/758793:BRPE64_RS01450 ^@ http://purl.uniprot.org/uniprot/R4WVX1 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/758793:BRPE64_RS10775 ^@ http://purl.uniprot.org/uniprot/R4WSR1 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/758793:BRPE64_RS21370 ^@ http://purl.uniprot.org/uniprot/R4X3B2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS20145 ^@ http://purl.uniprot.org/uniprot/R4WXJ0 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/758793:BRPE64_RS08390 ^@ http://purl.uniprot.org/uniprot/R4WHA5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/758793:BRPE64_RS26955 ^@ http://purl.uniprot.org/uniprot/R4X011 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS13315 ^@ http://purl.uniprot.org/uniprot/R4X0M2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/758793:BRPE64_RS14220 ^@ http://purl.uniprot.org/uniprot/R4WZ60 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS02115 ^@ http://purl.uniprot.org/uniprot/R4WMV8 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/758793:BRPE64_RS16810 ^@ http://purl.uniprot.org/uniprot/R4WLC8 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/758793:BRPE64_RS09610 ^@ http://purl.uniprot.org/uniprot/R4WXI9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/758793:BRPE64_RS17615 ^@ http://purl.uniprot.org/uniprot/R4WLF5 ^@ Function ^@ May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit. http://togogenome.org/gene/758793:BRPE64_RS03835 ^@ http://purl.uniprot.org/uniprot/R4WX68 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DsbB family.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein. http://togogenome.org/gene/758793:BRPE64_RS23730 ^@ http://purl.uniprot.org/uniprot/R4X2J1 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/758793:BRPE64_RS10015 ^@ http://purl.uniprot.org/uniprot/R4WXN4 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. http://togogenome.org/gene/758793:BRPE64_RS09245 ^@ http://purl.uniprot.org/uniprot/R4WRW0 ^@ Similarity ^@ Belongs to the GppA/Ppx family. http://togogenome.org/gene/758793:BRPE64_RS15690 ^@ http://purl.uniprot.org/uniprot/R4X1H4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS09555 ^@ http://purl.uniprot.org/uniprot/R4WHU8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/758793:BRPE64_RS17080 ^@ http://purl.uniprot.org/uniprot/R4X065 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/758793:BRPE64_RS11635 ^@ http://purl.uniprot.org/uniprot/R4WY84 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS13185 ^@ http://purl.uniprot.org/uniprot/R4WU18 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/758793:BRPE64_RS28845 ^@ http://purl.uniprot.org/uniprot/R4WTD1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS16070 ^@ http://purl.uniprot.org/uniprot/R4WKK8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS05920 ^@ http://purl.uniprot.org/uniprot/R4WGM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS29945 ^@ http://purl.uniprot.org/uniprot/R4X149 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.|||Bacterial flagellum basal body|||Belongs to the YcgR family.|||Monomer. Interacts with the flagellar basal bodies. http://togogenome.org/gene/758793:BRPE64_RS21715 ^@ http://purl.uniprot.org/uniprot/R4WY61 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS05370 ^@ http://purl.uniprot.org/uniprot/R4WG89 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/758793:BRPE64_RS31140 ^@ http://purl.uniprot.org/uniprot/A0A060PGZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS10785 ^@ http://purl.uniprot.org/uniprot/R4WI44 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/758793:BRPE64_RS12080 ^@ http://purl.uniprot.org/uniprot/R4X089 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/758793:BRPE64_RS24405 ^@ http://purl.uniprot.org/uniprot/R4WZ28 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.|||Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids. http://togogenome.org/gene/758793:BRPE64_RS26325 ^@ http://purl.uniprot.org/uniprot/R4X3B8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS30510 ^@ http://purl.uniprot.org/uniprot/R4WUD6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS20025 ^@ http://purl.uniprot.org/uniprot/R4X146 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS24415 ^@ http://purl.uniprot.org/uniprot/R4X405 ^@ Similarity ^@ Belongs to the proline racemase family. http://togogenome.org/gene/758793:BRPE64_RS01650 ^@ http://purl.uniprot.org/uniprot/R4WF02 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/758793:BRPE64_RS22250 ^@ http://purl.uniprot.org/uniprot/R4X3I7 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/758793:BRPE64_RS23965 ^@ http://purl.uniprot.org/uniprot/R4WQF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS12315 ^@ http://purl.uniprot.org/uniprot/R4X0B7 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/758793:BRPE64_RS13565 ^@ http://purl.uniprot.org/uniprot/R4WJD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS04915 ^@ http://purl.uniprot.org/uniprot/R4WPJ5 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/758793:BRPE64_RS24720 ^@ http://purl.uniprot.org/uniprot/R4WQH4 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/758793:BRPE64_RS05255 ^@ http://purl.uniprot.org/uniprot/R4WPP8 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS02515 ^@ http://purl.uniprot.org/uniprot/R4WTT3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/758793:BRPE64_RS01815 ^@ http://purl.uniprot.org/uniprot/R4WTA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS20485 ^@ http://purl.uniprot.org/uniprot/R4X1A8 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/758793:BRPE64_RS25245 ^@ http://purl.uniprot.org/uniprot/R4X318 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the peroxidase family. Peroxidase/catalase subfamily.|||Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.|||Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS03845 ^@ http://purl.uniprot.org/uniprot/R4WFY3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS07975 ^@ http://purl.uniprot.org/uniprot/R4WHA7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/758793:BRPE64_RS00955 ^@ http://purl.uniprot.org/uniprot/R4WF07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS17975 ^@ http://purl.uniprot.org/uniprot/R4X298 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/758793:BRPE64_RS01295 ^@ http://purl.uniprot.org/uniprot/R4WVT7 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/758793:BRPE64_RS15725 ^@ http://purl.uniprot.org/uniprot/R4WVG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS25730 ^@ http://purl.uniprot.org/uniprot/R4X4B9 ^@ Similarity ^@ Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family. http://togogenome.org/gene/758793:BRPE64_RS27175 ^@ http://purl.uniprot.org/uniprot/R4X4P2 ^@ Activity Regulation|||Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.|||Belongs to the TPP enzyme family.|||Binds 1 FAD per subunit.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Cell membrane|||Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus. http://togogenome.org/gene/758793:BRPE64_RS10780 ^@ http://purl.uniprot.org/uniprot/R4WXX6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/758793:BRPE64_RS11850 ^@ http://purl.uniprot.org/uniprot/R4WYB6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/758793:BRPE64_RS20165 ^@ http://purl.uniprot.org/uniprot/R4WN42 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/758793:BRPE64_RS09565 ^@ http://purl.uniprot.org/uniprot/R4WXI4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/758793:BRPE64_RS05050 ^@ http://purl.uniprot.org/uniprot/R4WG52 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterioferritin family.|||Iron-storage protein.|||Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited. http://togogenome.org/gene/758793:BRPE64_RS13640 ^@ http://purl.uniprot.org/uniprot/R4WUB0 ^@ Similarity ^@ Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. http://togogenome.org/gene/758793:BRPE64_RS16020 ^@ http://purl.uniprot.org/uniprot/R4WKJ8 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/758793:BRPE64_RS11160 ^@ http://purl.uniprot.org/uniprot/R4WSY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS30550 ^@ http://purl.uniprot.org/uniprot/R4X5G2 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/758793:BRPE64_RS04645 ^@ http://purl.uniprot.org/uniprot/R4WFZ6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.|||Belongs to the helicase family. UvrD subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.|||The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.|||The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC. http://togogenome.org/gene/758793:BRPE64_RS17665 ^@ http://purl.uniprot.org/uniprot/R4WLG2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/758793:BRPE64_RS11755 ^@ http://purl.uniprot.org/uniprot/R4WIK1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/758793:BRPE64_RS13160 ^@ http://purl.uniprot.org/uniprot/R4WU12 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/758793:BRPE64_RS22995 ^@ http://purl.uniprot.org/uniprot/R4WPR0 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/758793:BRPE64_RS23170 ^@ http://purl.uniprot.org/uniprot/R4WPK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/758793:BRPE64_RS04125 ^@ http://purl.uniprot.org/uniprot/R4WG11 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/758793:BRPE64_RS26865 ^@ http://purl.uniprot.org/uniprot/R4X001 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS20305 ^@ http://purl.uniprot.org/uniprot/R4X330 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS05695 ^@ http://purl.uniprot.org/uniprot/R4WVH5 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS13875 ^@ http://purl.uniprot.org/uniprot/R4WUF9 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/758793:BRPE64_RS24220 ^@ http://purl.uniprot.org/uniprot/R4X3Y5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS06525 ^@ http://purl.uniprot.org/uniprot/R4WGU4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/758793:BRPE64_RS03935 ^@ http://purl.uniprot.org/uniprot/R4WFR0 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/758793:BRPE64_RS13140 ^@ http://purl.uniprot.org/uniprot/R4WYR8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.|||In the C-terminal section; belongs to the glycosyl hydrolase 73 family.|||In the N-terminal section; belongs to the FlgJ family.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS03145 ^@ http://purl.uniprot.org/uniprot/R4WFR8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/758793:BRPE64_RS01915 ^@ http://purl.uniprot.org/uniprot/R4WFB5 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/758793:BRPE64_RS28110 ^@ http://purl.uniprot.org/uniprot/R4X0G5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/758793:BRPE64_RS23555 ^@ http://purl.uniprot.org/uniprot/R4WYS0 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/758793:BRPE64_RS00835 ^@ http://purl.uniprot.org/uniprot/R4WEQ3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS27615 ^@ http://purl.uniprot.org/uniprot/R4WSC8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS16075 ^@ http://purl.uniprot.org/uniprot/R4WKV7 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS23605 ^@ http://purl.uniprot.org/uniprot/R4WYS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS00695 ^@ http://purl.uniprot.org/uniprot/R4WEP1 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/758793:BRPE64_RS05780 ^@ http://purl.uniprot.org/uniprot/R4WGL3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/758793:BRPE64_RS14010 ^@ http://purl.uniprot.org/uniprot/R4WZ31 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS31415 ^@ http://purl.uniprot.org/uniprot/A0A060PH49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS05665 ^@ http://purl.uniprot.org/uniprot/R4WPW9 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/758793:BRPE64_RS10305 ^@ http://purl.uniprot.org/uniprot/R4WHX8 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/758793:BRPE64_RS08035 ^@ http://purl.uniprot.org/uniprot/R4WH68 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/758793:BRPE64_RS15685 ^@ http://purl.uniprot.org/uniprot/R4WZN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAE transporter (TC 2.A.81) family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS16485 ^@ http://purl.uniprot.org/uniprot/R4WKV0 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/758793:BRPE64_RS11530 ^@ http://purl.uniprot.org/uniprot/R4WT50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/758793:BRPE64_RS25310 ^@ http://purl.uniprot.org/uniprot/R4WR57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS11000 ^@ http://purl.uniprot.org/uniprot/R4WZT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP H family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS00115 ^@ http://purl.uniprot.org/uniprot/R4WLT5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS23600 ^@ http://purl.uniprot.org/uniprot/R4WQ54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS11475 ^@ http://purl.uniprot.org/uniprot/R4WT40 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/758793:BRPE64_RS15455 ^@ http://purl.uniprot.org/uniprot/R4WZK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS05015 ^@ http://purl.uniprot.org/uniprot/R4WV57 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/758793:BRPE64_RS10090 ^@ http://purl.uniprot.org/uniprot/R4WHV3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS07495 ^@ http://purl.uniprot.org/uniprot/R4WYL6 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/758793:BRPE64_RS03050 ^@ http://purl.uniprot.org/uniprot/R4WNE7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS19795 ^@ http://purl.uniprot.org/uniprot/R4WXG1 ^@ Function|||Similarity ^@ Belongs to the AMP nucleosidase family.|||Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. http://togogenome.org/gene/758793:BRPE64_RS05620 ^@ http://purl.uniprot.org/uniprot/R4WPW1 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/758793:BRPE64_RS02040 ^@ http://purl.uniprot.org/uniprot/R4WMU0 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS06410 ^@ http://purl.uniprot.org/uniprot/R4WVV9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phospholipase A1 family.|||Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.|||Cell outer membrane|||Homodimer; dimerization is reversible, and the dimeric form is the active one.|||Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS12790 ^@ http://purl.uniprot.org/uniprot/R4WJ07 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily. http://togogenome.org/gene/758793:BRPE64_RS03915 ^@ http://purl.uniprot.org/uniprot/R4WFZ2 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/758793:BRPE64_RS03675 ^@ http://purl.uniprot.org/uniprot/R4WNP0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/758793:BRPE64_RS17740 ^@ http://purl.uniprot.org/uniprot/R4WLR3 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/758793:BRPE64_RS20105 ^@ http://purl.uniprot.org/uniprot/R4WMU7 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/758793:BRPE64_RS13880 ^@ http://purl.uniprot.org/uniprot/R4WZ13 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/758793:BRPE64_RS30920 ^@ http://purl.uniprot.org/uniprot/A0A060PQR0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS03170 ^@ http://purl.uniprot.org/uniprot/R4WFI1 ^@ Subcellular Location Annotation ^@ Cell outer membrane http://togogenome.org/gene/758793:BRPE64_RS24945 ^@ http://purl.uniprot.org/uniprot/R4X2Y0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/758793:BRPE64_RS21565 ^@ http://purl.uniprot.org/uniprot/R4WNS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS00420 ^@ http://purl.uniprot.org/uniprot/R4WLY5 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/758793:BRPE64_RS25055 ^@ http://purl.uniprot.org/uniprot/R4WZ92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS12040 ^@ http://purl.uniprot.org/uniprot/R4WIX7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS25970 ^@ http://purl.uniprot.org/uniprot/R4WZP0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS04825 ^@ http://purl.uniprot.org/uniprot/R4WG29 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/758793:BRPE64_RS23260 ^@ http://purl.uniprot.org/uniprot/R4WPY0 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/758793:BRPE64_RS27155 ^@ http://purl.uniprot.org/uniprot/R4WS30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS00135 ^@ http://purl.uniprot.org/uniprot/R4WLT8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/758793:BRPE64_RS09755 ^@ http://purl.uniprot.org/uniprot/R4WHW8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/758793:BRPE64_RS33780 ^@ http://purl.uniprot.org/uniprot/R4X3N6 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/758793:BRPE64_RS06290 ^@ http://purl.uniprot.org/uniprot/R4WQ75 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/758793:BRPE64_RS09600 ^@ http://purl.uniprot.org/uniprot/R4WHQ9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/758793:BRPE64_RS04530 ^@ http://purl.uniprot.org/uniprot/R4WFY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/758793:BRPE64_RS15290 ^@ http://purl.uniprot.org/uniprot/R4WV79 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/758793:BRPE64_RS19515 ^@ http://purl.uniprot.org/uniprot/R4WMI8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase S45 family.|||Binds 1 Ca(2+) ion per dimer. http://togogenome.org/gene/758793:BRPE64_RS19405 ^@ http://purl.uniprot.org/uniprot/R4WMH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS11855 ^@ http://purl.uniprot.org/uniprot/R4X045 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/758793:BRPE64_RS10960 ^@ http://purl.uniprot.org/uniprot/R4WID0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS21345 ^@ http://purl.uniprot.org/uniprot/R4X3B0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS25580 ^@ http://purl.uniprot.org/uniprot/R4WRC9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS31510 ^@ http://purl.uniprot.org/uniprot/A0A060PRR1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/758793:BRPE64_RS12445 ^@ http://purl.uniprot.org/uniprot/R4WIW0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/758793:BRPE64_RS05545 ^@ http://purl.uniprot.org/uniprot/R4WGI7 ^@ Similarity ^@ Belongs to the malate synthase family. http://togogenome.org/gene/758793:BRPE64_RS02135 ^@ http://purl.uniprot.org/uniprot/R4WFE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS30705 ^@ http://purl.uniprot.org/uniprot/R4X4G0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS24860 ^@ http://purl.uniprot.org/uniprot/R4WQU3 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/758793:BRPE64_RS00525 ^@ http://purl.uniprot.org/uniprot/R4WSK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/758793:BRPE64_RS29310 ^@ http://purl.uniprot.org/uniprot/R4WTK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS03315 ^@ http://purl.uniprot.org/uniprot/R4WFJ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS14430 ^@ http://purl.uniprot.org/uniprot/R4WK10 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/758793:BRPE64_RS25355 ^@ http://purl.uniprot.org/uniprot/R4WR69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS02345 ^@ http://purl.uniprot.org/uniprot/R4WFJ2 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/758793:BRPE64_RS10895 ^@ http://purl.uniprot.org/uniprot/R4WST5 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/758793:BRPE64_RS12770 ^@ http://purl.uniprot.org/uniprot/R4WJ65 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/758793:BRPE64_RS18840 ^@ http://purl.uniprot.org/uniprot/R4WMC1 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS03330 ^@ http://purl.uniprot.org/uniprot/R4WU77 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS06420 ^@ http://purl.uniprot.org/uniprot/R4WVW4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/758793:BRPE64_RS04565 ^@ http://purl.uniprot.org/uniprot/R4WUU8 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/758793:BRPE64_RS09480 ^@ http://purl.uniprot.org/uniprot/R4WHN4 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/758793:BRPE64_RS19320 ^@ http://purl.uniprot.org/uniprot/R4WMQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS15265 ^@ http://purl.uniprot.org/uniprot/R4WV74 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/758793:BRPE64_RS24175 ^@ http://purl.uniprot.org/uniprot/R4X3Y2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS08135 ^@ http://purl.uniprot.org/uniprot/R4WH77 ^@ Cofactor ^@ Binds 3 heme c groups covalently per subunit. http://togogenome.org/gene/758793:BRPE64_RS22920 ^@ http://purl.uniprot.org/uniprot/R4X269 ^@ Function|||Similarity ^@ Belongs to the ClpA/ClpB family.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK. http://togogenome.org/gene/758793:BRPE64_RS10170 ^@ http://purl.uniprot.org/uniprot/R4WXQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS29790 ^@ http://purl.uniprot.org/uniprot/R4X597 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS12165 ^@ http://purl.uniprot.org/uniprot/R4WTJ5 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/758793:BRPE64_RS15490 ^@ http://purl.uniprot.org/uniprot/R4WK95 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS07730 ^@ http://purl.uniprot.org/uniprot/R4WH78 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/758793:BRPE64_RS20335 ^@ http://purl.uniprot.org/uniprot/R4WMY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS05275 ^@ http://purl.uniprot.org/uniprot/R4WGF9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS08815 ^@ http://purl.uniprot.org/uniprot/R4WHJ9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS08005 ^@ http://purl.uniprot.org/uniprot/R4WYS4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS30190 ^@ http://purl.uniprot.org/uniprot/R4WU56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/758793:BRPE64_RS24045 ^@ http://purl.uniprot.org/uniprot/R4WYZ0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS03865 ^@ http://purl.uniprot.org/uniprot/R4WFQ3 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS04015 ^@ http://purl.uniprot.org/uniprot/R4WNV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS08440 ^@ http://purl.uniprot.org/uniprot/R4WYW2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS16655 ^@ http://purl.uniprot.org/uniprot/R4X013 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS09790 ^@ http://purl.uniprot.org/uniprot/R4WZE7 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/758793:BRPE64_RS30860 ^@ http://purl.uniprot.org/uniprot/A0A060PR90 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS10425 ^@ http://purl.uniprot.org/uniprot/R4WZM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS01100 ^@ http://purl.uniprot.org/uniprot/R4WF21 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS10245 ^@ http://purl.uniprot.org/uniprot/R4WXR1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UreE family.|||Cytoplasm|||Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. http://togogenome.org/gene/758793:BRPE64_RS20435 ^@ http://purl.uniprot.org/uniprot/R4WXN0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.|||Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS13685 ^@ http://purl.uniprot.org/uniprot/R4WUC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS19170 ^@ http://purl.uniprot.org/uniprot/R4WMD9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/758793:BRPE64_RS03350 ^@ http://purl.uniprot.org/uniprot/R4WU82 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS01805 ^@ http://purl.uniprot.org/uniprot/R4WF96 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.|||Cell inner membrane http://togogenome.org/gene/758793:BRPE64_RS02000 ^@ http://purl.uniprot.org/uniprot/R4WTE6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/758793:BRPE64_RS12435 ^@ http://purl.uniprot.org/uniprot/R4WYI8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/758793:BRPE64_RS11715 ^@ http://purl.uniprot.org/uniprot/R4WIP7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/758793:BRPE64_RS29815 ^@ http://purl.uniprot.org/uniprot/R4WTS7 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/758793:BRPE64_RS02760 ^@ http://purl.uniprot.org/uniprot/R4WFE6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS04120 ^@ http://purl.uniprot.org/uniprot/R4WFT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS26430 ^@ http://purl.uniprot.org/uniprot/R4WRX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS27320 ^@ http://purl.uniprot.org/uniprot/R4WSD2 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/758793:BRPE64_RS03665 ^@ http://purl.uniprot.org/uniprot/R4WFN1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/758793:BRPE64_RS20180 ^@ http://purl.uniprot.org/uniprot/R4X321 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS15585 ^@ http://purl.uniprot.org/uniprot/R4WKK1 ^@ Function|||Similarity ^@ Belongs to the catalase family. HPII subfamily.|||Serves to protect cells from the toxic effects of hydrogen peroxide. http://togogenome.org/gene/758793:BRPE64_RS22225 ^@ http://purl.uniprot.org/uniprot/R4X3I5 ^@ Similarity ^@ Belongs to the GST superfamily. NadH family. http://togogenome.org/gene/758793:BRPE64_RS27460 ^@ http://purl.uniprot.org/uniprot/R4X4R4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS10220 ^@ http://purl.uniprot.org/uniprot/R4WXQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS21510 ^@ http://purl.uniprot.org/uniprot/R4X3D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS21145 ^@ http://purl.uniprot.org/uniprot/R4X395 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS21020 ^@ http://purl.uniprot.org/uniprot/R4WND3 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/758793:BRPE64_RS17620 ^@ http://purl.uniprot.org/uniprot/R4WLP5 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS12490 ^@ http://purl.uniprot.org/uniprot/R4WIW7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/758793:BRPE64_RS22525 ^@ http://purl.uniprot.org/uniprot/R4X3K9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS15790 ^@ http://purl.uniprot.org/uniprot/R4WKF2 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/758793:BRPE64_RS21425 ^@ http://purl.uniprot.org/uniprot/R4WNQ4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS00315 ^@ http://purl.uniprot.org/uniprot/R4WSH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/758793:BRPE64_RS01390 ^@ http://purl.uniprot.org/uniprot/R4WEX0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/758793:BRPE64_RS11560 ^@ http://purl.uniprot.org/uniprot/R4WY73 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/758793:BRPE64_RS11415 ^@ http://purl.uniprot.org/uniprot/R4WY51 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/758793:BRPE64_RS25320 ^@ http://purl.uniprot.org/uniprot/R4X325 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS24090 ^@ http://purl.uniprot.org/uniprot/R4WYZ5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS21435 ^@ http://purl.uniprot.org/uniprot/R4WY34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS08175 ^@ http://purl.uniprot.org/uniprot/R4WYU1 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/758793:BRPE64_RS05500 ^@ http://purl.uniprot.org/uniprot/R4WGI1 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. http://togogenome.org/gene/758793:BRPE64_RS11190 ^@ http://purl.uniprot.org/uniprot/R4WY23 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ureidoglycolate lyase family.|||Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS22450 ^@ http://purl.uniprot.org/uniprot/R4X209 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterioferritin family.|||Iron-storage protein.|||Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited. http://togogenome.org/gene/758793:BRPE64_RS21505 ^@ http://purl.uniprot.org/uniprot/R4X317 ^@ Cofactor|||Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/758793:BRPE64_RS10225 ^@ http://purl.uniprot.org/uniprot/R4WZJ7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/758793:BRPE64_RS26650 ^@ http://purl.uniprot.org/uniprot/R4WS09 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS11385 ^@ http://purl.uniprot.org/uniprot/R4WIJ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/758793:BRPE64_RS23380 ^@ http://purl.uniprot.org/uniprot/R4WPQ6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS10520 ^@ http://purl.uniprot.org/uniprot/R4WXU5 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/758793:BRPE64_RS09290 ^@ http://purl.uniprot.org/uniprot/R4WHQ1 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/758793:BRPE64_RS09830 ^@ http://purl.uniprot.org/uniprot/R4WZF2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS01290 ^@ http://purl.uniprot.org/uniprot/R4WSZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS11130 ^@ http://purl.uniprot.org/uniprot/R4WIF8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IlvD/Edd family.|||Binds 1 [4Fe-4S] cluster.|||Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate. http://togogenome.org/gene/758793:BRPE64_RS29025 ^@ http://purl.uniprot.org/uniprot/R4X532 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/758793:BRPE64_RS07660 ^@ http://purl.uniprot.org/uniprot/R4WR10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS24545 ^@ http://purl.uniprot.org/uniprot/R4X417 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS12365 ^@ http://purl.uniprot.org/uniprot/R4X0C2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/758793:BRPE64_RS31880 ^@ http://purl.uniprot.org/uniprot/R4WSF9 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/758793:BRPE64_RS03680 ^@ http://purl.uniprot.org/uniprot/R4WX52 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/758793:BRPE64_RS03320 ^@ http://purl.uniprot.org/uniprot/R4WFT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolA family.|||Monomer.|||Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS05960 ^@ http://purl.uniprot.org/uniprot/R4WXZ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/758793:BRPE64_RS18415 ^@ http://purl.uniprot.org/uniprot/R4X0L3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/758793:BRPE64_RS11625 ^@ http://purl.uniprot.org/uniprot/R4WIN6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS12825 ^@ http://purl.uniprot.org/uniprot/R4WTV1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TtcA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.|||Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.|||Cytoplasm|||Homodimer.|||The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster. http://togogenome.org/gene/758793:BRPE64_RS08370 ^@ http://purl.uniprot.org/uniprot/R4WHA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS00635 ^@ http://purl.uniprot.org/uniprot/R4WM20 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/758793:BRPE64_RS21165 ^@ http://purl.uniprot.org/uniprot/R4X1J6 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the L-aspartate dehydrogenase family.|||Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.|||The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia. http://togogenome.org/gene/758793:BRPE64_RS12370 ^@ http://purl.uniprot.org/uniprot/R4WIV1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/758793:BRPE64_RS21030 ^@ http://purl.uniprot.org/uniprot/R4X1I1 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/758793:BRPE64_RS05970 ^@ http://purl.uniprot.org/uniprot/R4WQ16 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS12530 ^@ http://purl.uniprot.org/uniprot/R4WTP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/758793:BRPE64_RS26920 ^@ http://purl.uniprot.org/uniprot/R4X3H0 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/758793:BRPE64_RS11870 ^@ http://purl.uniprot.org/uniprot/R4WTD2 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/758793:BRPE64_RS05020 ^@ http://purl.uniprot.org/uniprot/R4WXN2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS20055 ^@ http://purl.uniprot.org/uniprot/R4X310 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/758793:BRPE64_RS11860 ^@ http://purl.uniprot.org/uniprot/R4WIM2 ^@ Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily. http://togogenome.org/gene/758793:BRPE64_RS25485 ^@ http://purl.uniprot.org/uniprot/R4WRA5 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS06535 ^@ http://purl.uniprot.org/uniprot/R4WVY8 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/758793:BRPE64_RS27825 ^@ http://purl.uniprot.org/uniprot/R4X4U4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS12655 ^@ http://purl.uniprot.org/uniprot/R4WJ51 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS21400 ^@ http://purl.uniprot.org/uniprot/R4WNP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the encapsulin family. Family 1 subfamily.|||Encapsulin nanocompartment http://togogenome.org/gene/758793:BRPE64_RS11195 ^@ http://purl.uniprot.org/uniprot/R4WZW2 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/758793:BRPE64_RS17625 ^@ http://purl.uniprot.org/uniprot/R4WWE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aromatic amine dehydrogenase heavy chain family.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS23895 ^@ http://purl.uniprot.org/uniprot/R4X2L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS28930 ^@ http://purl.uniprot.org/uniprot/R4X410 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS15485 ^@ http://purl.uniprot.org/uniprot/R4X1F1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS30290 ^@ http://purl.uniprot.org/uniprot/R4X1A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS14170 ^@ http://purl.uniprot.org/uniprot/R4WZ53 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS29410 ^@ http://purl.uniprot.org/uniprot/R4WTL9 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/758793:BRPE64_RS23325 ^@ http://purl.uniprot.org/uniprot/R4X3S2 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/758793:BRPE64_RS10815 ^@ http://purl.uniprot.org/uniprot/R4WIA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS27270 ^@ http://purl.uniprot.org/uniprot/R4WS49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS02365 ^@ http://purl.uniprot.org/uniprot/R4WFJ4 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/758793:BRPE64_RS29290 ^@ http://purl.uniprot.org/uniprot/R4WTJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS07970 ^@ http://purl.uniprot.org/uniprot/R4WH60 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/758793:BRPE64_RS20090 ^@ http://purl.uniprot.org/uniprot/R4WXI5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/758793:BRPE64_RS18820 ^@ http://purl.uniprot.org/uniprot/R4WMB5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS20080 ^@ http://purl.uniprot.org/uniprot/R4WMU2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS03810 ^@ http://purl.uniprot.org/uniprot/R4WX65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS09620 ^@ http://purl.uniprot.org/uniprot/R4WHR1 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/758793:BRPE64_RS15240 ^@ http://purl.uniprot.org/uniprot/R4WK47 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/758793:BRPE64_RS20450 ^@ http://purl.uniprot.org/uniprot/R4WN06 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS10625 ^@ http://purl.uniprot.org/uniprot/R4WZP3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS00625 ^@ http://purl.uniprot.org/uniprot/R4WEN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/758793:BRPE64_RS04885 ^@ http://purl.uniprot.org/uniprot/R4WGB8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/758793:BRPE64_RS02520 ^@ http://purl.uniprot.org/uniprot/R4WWM5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS04030 ^@ http://purl.uniprot.org/uniprot/R4WFS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS01380 ^@ http://purl.uniprot.org/uniprot/R4WT13 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS16320 ^@ http://purl.uniprot.org/uniprot/R4WKR0 ^@ Function|||Subcellular Location Annotation ^@ Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.|||Cell inner membrane http://togogenome.org/gene/758793:BRPE64_RS23755 ^@ http://purl.uniprot.org/uniprot/R4X3V7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS30720 ^@ http://purl.uniprot.org/uniprot/R4X4H0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/758793:BRPE64_RS11785 ^@ http://purl.uniprot.org/uniprot/R4WIQ9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/758793:BRPE64_RS04520 ^@ http://purl.uniprot.org/uniprot/R4WUT6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/758793:BRPE64_RS17985 ^@ http://purl.uniprot.org/uniprot/R4WWL3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class II subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/758793:BRPE64_RS07775 ^@ http://purl.uniprot.org/uniprot/R4WH84 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/758793:BRPE64_RS13285 ^@ http://purl.uniprot.org/uniprot/R4WJE3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Cell membrane|||Membrane|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/758793:BRPE64_RS11305 ^@ http://purl.uniprot.org/uniprot/R4WT09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS17575 ^@ http://purl.uniprot.org/uniprot/R4WWD7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS31065 ^@ http://purl.uniprot.org/uniprot/A0A060PRE9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS03770 ^@ http://purl.uniprot.org/uniprot/R4WFX5 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/758793:BRPE64_RS12980 ^@ http://purl.uniprot.org/uniprot/R4WJ33 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/758793:BRPE64_RS22575 ^@ http://purl.uniprot.org/uniprot/R4X3L2 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/758793:BRPE64_RS02815 ^@ http://purl.uniprot.org/uniprot/R4WNA4 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/758793:BRPE64_RS28375 ^@ http://purl.uniprot.org/uniprot/R4WT18 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/758793:BRPE64_RS03195 ^@ http://purl.uniprot.org/uniprot/R4WFI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fimbrial export usher family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS27230 ^@ http://purl.uniprot.org/uniprot/R4WS39 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/758793:BRPE64_RS05425 ^@ http://purl.uniprot.org/uniprot/R4WGH4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/758793:BRPE64_RS12440 ^@ http://purl.uniprot.org/uniprot/R4X0D1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/758793:BRPE64_RS31055 ^@ http://purl.uniprot.org/uniprot/A0A060PJC7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS03685 ^@ http://purl.uniprot.org/uniprot/R4WFN3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/758793:BRPE64_RS03120 ^@ http://purl.uniprot.org/uniprot/R4WFR6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS15760 ^@ http://purl.uniprot.org/uniprot/R4X1I2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS31650 ^@ http://purl.uniprot.org/uniprot/A0A060PR93 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS21170 ^@ http://purl.uniprot.org/uniprot/R4X396 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/758793:BRPE64_RS23760 ^@ http://purl.uniprot.org/uniprot/R4WQ22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS09575 ^@ http://purl.uniprot.org/uniprot/R4WHQ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YceF subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/758793:BRPE64_RS09075 ^@ http://purl.uniprot.org/uniprot/R4WRR9 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/758793:BRPE64_RS04965 ^@ http://purl.uniprot.org/uniprot/R4WV48 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS29420 ^@ http://purl.uniprot.org/uniprot/R4X452 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS04595 ^@ http://purl.uniprot.org/uniprot/R4WXG4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS28060 ^@ http://purl.uniprot.org/uniprot/R4X0F7 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/758793:BRPE64_RS14055 ^@ http://purl.uniprot.org/uniprot/R4WJL2 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/758793:BRPE64_RS04400 ^@ http://purl.uniprot.org/uniprot/R4WXD4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/758793:BRPE64_RS26025 ^@ http://purl.uniprot.org/uniprot/R4X4E9 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/758793:BRPE64_RS01125 ^@ http://purl.uniprot.org/uniprot/R4WF23 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/758793:BRPE64_RS28670 ^@ http://purl.uniprot.org/uniprot/R4X513 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS12045 ^@ http://purl.uniprot.org/uniprot/R4WTH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/758793:BRPE64_RS02325 ^@ http://purl.uniprot.org/uniprot/R4WN24 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS11010 ^@ http://purl.uniprot.org/uniprot/R4WID8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS13305 ^@ http://purl.uniprot.org/uniprot/R4WJE7 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/758793:BRPE64_RS31295 ^@ http://purl.uniprot.org/uniprot/A0A060PRK6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS17200 ^@ http://purl.uniprot.org/uniprot/R4X078 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS14115 ^@ http://purl.uniprot.org/uniprot/R4WUJ5 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS17905 ^@ http://purl.uniprot.org/uniprot/R4WLK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS18855 ^@ http://purl.uniprot.org/uniprot/R4X2J3 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/758793:BRPE64_RS03805 ^@ http://purl.uniprot.org/uniprot/R4WUE8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. http://togogenome.org/gene/758793:BRPE64_RS08230 ^@ http://purl.uniprot.org/uniprot/R4WHD4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/758793:BRPE64_RS07345 ^@ http://purl.uniprot.org/uniprot/R4WYJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS17650 ^@ http://purl.uniprot.org/uniprot/R4WWE8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS01010 ^@ http://purl.uniprot.org/uniprot/R4WM85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS05240 ^@ http://purl.uniprot.org/uniprot/R4WXQ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinylarginine dihydrolase family.|||Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS08830 ^@ http://purl.uniprot.org/uniprot/R4WZ18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS22330 ^@ http://purl.uniprot.org/uniprot/R4WYB9 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/758793:BRPE64_RS23360 ^@ http://purl.uniprot.org/uniprot/R4WPZ7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/758793:BRPE64_RS07905 ^@ http://purl.uniprot.org/uniprot/R4WWS6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS20890 ^@ http://purl.uniprot.org/uniprot/R4WXU6 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS11240 ^@ http://purl.uniprot.org/uniprot/R4WZW8 ^@ Similarity ^@ Belongs to the ribonuclease N1/T1 family. http://togogenome.org/gene/758793:BRPE64_RS21630 ^@ http://purl.uniprot.org/uniprot/R4X3E0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS01275 ^@ http://purl.uniprot.org/uniprot/R4WEV5 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/758793:BRPE64_RS23090 ^@ http://purl.uniprot.org/uniprot/R4X294 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS09475 ^@ http://purl.uniprot.org/uniprot/R4WZ99 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/758793:BRPE64_RS01020 ^@ http://purl.uniprot.org/uniprot/R4WVN6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS02805 ^@ http://purl.uniprot.org/uniprot/R4WFF1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/758793:BRPE64_RS03065 ^@ http://purl.uniprot.org/uniprot/R4WFH3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/758793:BRPE64_RS26720 ^@ http://purl.uniprot.org/uniprot/R4WS20 ^@ Caution|||Similarity ^@ Belongs to the spermidine/spermine synthase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS12075 ^@ http://purl.uniprot.org/uniprot/R4WYF1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/758793:BRPE64_RS10585 ^@ http://purl.uniprot.org/uniprot/R4WI71 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS20015 ^@ http://purl.uniprot.org/uniprot/R4WMT0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the trans-sulfuration enzymes family. MetZ subfamily.|||Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.|||Homotetramer. http://togogenome.org/gene/758793:BRPE64_RS21850 ^@ http://purl.uniprot.org/uniprot/R4WNW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS21365 ^@ http://purl.uniprot.org/uniprot/R4X1M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS15895 ^@ http://purl.uniprot.org/uniprot/R4WZQ5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS31500 ^@ http://purl.uniprot.org/uniprot/A0A060PJN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS04480 ^@ http://purl.uniprot.org/uniprot/R4WFX7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS07325 ^@ http://purl.uniprot.org/uniprot/R4WH02 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/758793:BRPE64_RS29300 ^@ http://purl.uniprot.org/uniprot/R4X555 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS04500 ^@ http://purl.uniprot.org/uniprot/R4WXF1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS04525 ^@ http://purl.uniprot.org/uniprot/R4WXF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/758793:BRPE64_RS20115 ^@ http://purl.uniprot.org/uniprot/R4WNR9 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/758793:BRPE64_RS02240 ^@ http://purl.uniprot.org/uniprot/R4WTL8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/758793:BRPE64_RS05410 ^@ http://purl.uniprot.org/uniprot/R4WVC5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/758793:BRPE64_RS11150 ^@ http://purl.uniprot.org/uniprot/R4WIA3 ^@ Similarity ^@ Belongs to the DNA polymerase HolA subunit family. http://togogenome.org/gene/758793:BRPE64_RS12070 ^@ http://purl.uniprot.org/uniprot/R4WTI3 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS21685 ^@ http://purl.uniprot.org/uniprot/R4WNU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS28400 ^@ http://purl.uniprot.org/uniprot/R4WT22 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS19995 ^@ http://purl.uniprot.org/uniprot/R4WN15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS25380 ^@ http://purl.uniprot.org/uniprot/R4WZD7 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS02765 ^@ http://purl.uniprot.org/uniprot/R4WFN2 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/758793:BRPE64_RS13370 ^@ http://purl.uniprot.org/uniprot/R4WJ91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS10210 ^@ http://purl.uniprot.org/uniprot/R4WI23 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/758793:BRPE64_RS20120 ^@ http://purl.uniprot.org/uniprot/R4X3D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS00435 ^@ http://purl.uniprot.org/uniprot/R4WEM7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS13695 ^@ http://purl.uniprot.org/uniprot/R4X0S8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/758793:BRPE64_RS02685 ^@ http://purl.uniprot.org/uniprot/R4WN80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS22775 ^@ http://purl.uniprot.org/uniprot/R4X3M9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS21325 ^@ http://purl.uniprot.org/uniprot/R4WNK6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS10480 ^@ http://purl.uniprot.org/uniprot/R4WI55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS13555 ^@ http://purl.uniprot.org/uniprot/R4WYW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family. GSP D subfamily.|||Cell outer membrane http://togogenome.org/gene/758793:BRPE64_RS28065 ^@ http://purl.uniprot.org/uniprot/R4X3T0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS00285 ^@ http://purl.uniprot.org/uniprot/R4WLW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS00310 ^@ http://purl.uniprot.org/uniprot/R4WLW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS08610 ^@ http://purl.uniprot.org/uniprot/R4WYY7 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/758793:BRPE64_RS13745 ^@ http://purl.uniprot.org/uniprot/R4WJG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS26445 ^@ http://purl.uniprot.org/uniprot/R4X4H6 ^@ Similarity ^@ Belongs to the UPF0502 family. http://togogenome.org/gene/758793:BRPE64_RS29755 ^@ http://purl.uniprot.org/uniprot/R4X127 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS24705 ^@ http://purl.uniprot.org/uniprot/R4WZ58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/758793:BRPE64_RS09100 ^@ http://purl.uniprot.org/uniprot/R4WRS6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS22255 ^@ http://purl.uniprot.org/uniprot/R4WP25 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/758793:BRPE64_RS11770 ^@ http://purl.uniprot.org/uniprot/R4WYA2 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/758793:BRPE64_RS07890 ^@ http://purl.uniprot.org/uniprot/R4WH98 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS23650 ^@ http://purl.uniprot.org/uniprot/R4WYT4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS01210 ^@ http://purl.uniprot.org/uniprot/R4WF29 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/758793:BRPE64_RS30130 ^@ http://purl.uniprot.org/uniprot/R4X4B0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS29860 ^@ http://purl.uniprot.org/uniprot/R4WTT9 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the maleate isomerase family.|||Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.|||Homodimer.|||Reaction is initiated by nucleophilic attack of cysteine at the double bond, yielding a covalent succinylcysteine-like intermediate. http://togogenome.org/gene/758793:BRPE64_RS30205 ^@ http://purl.uniprot.org/uniprot/R4WU26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS03015 ^@ http://purl.uniprot.org/uniprot/R4WWW5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS12360 ^@ http://purl.uniprot.org/uniprot/R4WYH9 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/758793:BRPE64_RS05030 ^@ http://purl.uniprot.org/uniprot/R4WGD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS14750 ^@ http://purl.uniprot.org/uniprot/R4WUY9 ^@ Similarity ^@ Belongs to the phosphoribulokinase family. http://togogenome.org/gene/758793:BRPE64_RS08990 ^@ http://purl.uniprot.org/uniprot/R4WZ41 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS12095 ^@ http://purl.uniprot.org/uniprot/R4WYF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS18195 ^@ http://purl.uniprot.org/uniprot/R4WLQ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS18240 ^@ http://purl.uniprot.org/uniprot/R4X2D0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS12375 ^@ http://purl.uniprot.org/uniprot/R4WJ20 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/758793:BRPE64_RS13540 ^@ http://purl.uniprot.org/uniprot/R4X0Q2 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/758793:BRPE64_RS07480 ^@ http://purl.uniprot.org/uniprot/S0BC46 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS15920 ^@ http://purl.uniprot.org/uniprot/R4X1J5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/758793:BRPE64_RS21725 ^@ http://purl.uniprot.org/uniprot/R4X3E7 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/758793:BRPE64_RS31520 ^@ http://purl.uniprot.org/uniprot/A0A060PH77 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS05855 ^@ http://purl.uniprot.org/uniprot/R4WPZ8 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS31775 ^@ http://purl.uniprot.org/uniprot/A0A060PJV7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS12280 ^@ http://purl.uniprot.org/uniprot/R4WJ09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS07930 ^@ http://purl.uniprot.org/uniprot/R4WR58 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/758793:BRPE64_RS20005 ^@ http://purl.uniprot.org/uniprot/R4X143 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/758793:BRPE64_RS30350 ^@ http://purl.uniprot.org/uniprot/R4X5E4 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/758793:BRPE64_RS24925 ^@ http://purl.uniprot.org/uniprot/R4X449 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the calycin superfamily. Lipocalin family.|||Cell outer membrane|||Homodimer.|||Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids. http://togogenome.org/gene/758793:BRPE64_RS28710 ^@ http://purl.uniprot.org/uniprot/R4X0R2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/758793:BRPE64_RS27165 ^@ http://purl.uniprot.org/uniprot/R4X031 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/758793:BRPE64_RS16135 ^@ http://purl.uniprot.org/uniprot/R4WKM2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/758793:BRPE64_RS29465 ^@ http://purl.uniprot.org/uniprot/R4X0Z1 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/758793:BRPE64_RS27390 ^@ http://purl.uniprot.org/uniprot/R4WS74 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS12495 ^@ http://purl.uniprot.org/uniprot/R4WJ38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/758793:BRPE64_RS15640 ^@ http://purl.uniprot.org/uniprot/R4X1G8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS19340 ^@ http://purl.uniprot.org/uniprot/R4WXB9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS32140 ^@ http://purl.uniprot.org/uniprot/R4WQ67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0391 family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS05945 ^@ http://purl.uniprot.org/uniprot/R4WGN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ureidoglycolate lyase family.|||Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS04870 ^@ http://purl.uniprot.org/uniprot/R4WV31 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS28830 ^@ http://purl.uniprot.org/uniprot/R4X0S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS04005 ^@ http://purl.uniprot.org/uniprot/R4WFR9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/758793:BRPE64_RS03045 ^@ http://purl.uniprot.org/uniprot/R4WFQ9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS06035 ^@ http://purl.uniprot.org/uniprot/R4WQ30 ^@ Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS30125 ^@ http://purl.uniprot.org/uniprot/R4X176 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS10615 ^@ http://purl.uniprot.org/uniprot/R4WSM7 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.|||Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. http://togogenome.org/gene/758793:BRPE64_RS00095 ^@ http://purl.uniprot.org/uniprot/R4WER7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS25805 ^@ http://purl.uniprot.org/uniprot/R4WR79 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS05235 ^@ http://purl.uniprot.org/uniprot/R4WV94 ^@ Function|||Similarity ^@ Belongs to the aldehyde dehydrogenase family. AstD subfamily.|||Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. http://togogenome.org/gene/758793:BRPE64_RS08850 ^@ http://purl.uniprot.org/uniprot/R4WX78 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/758793:BRPE64_RS30180 ^@ http://purl.uniprot.org/uniprot/R4X5D0 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NapC/NirT/NrfH family.|||Binds 4 heme groups per subunit.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS13585 ^@ http://purl.uniprot.org/uniprot/R4X0R1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GSP I family.|||Cell inner membrane|||Cleaved by prepilin peptidase.|||Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.|||Membrane|||Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. http://togogenome.org/gene/758793:BRPE64_RS05795 ^@ http://purl.uniprot.org/uniprot/R4WXX7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/758793:BRPE64_RS05590 ^@ http://purl.uniprot.org/uniprot/R4WGJ2 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/758793:BRPE64_RS13170 ^@ http://purl.uniprot.org/uniprot/R4X0K8 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/758793:BRPE64_RS04685 ^@ http://purl.uniprot.org/uniprot/R4WG04 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS26960 ^@ http://purl.uniprot.org/uniprot/R4X3H5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS29380 ^@ http://purl.uniprot.org/uniprot/R4WTI5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/758793:BRPE64_RS02225 ^@ http://purl.uniprot.org/uniprot/R4WF76 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS00665 ^@ http://purl.uniprot.org/uniprot/R4WSN4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS26680 ^@ http://purl.uniprot.org/uniprot/R4X3E9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS02255 ^@ http://purl.uniprot.org/uniprot/R4WFH6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/758793:BRPE64_RS17680 ^@ http://purl.uniprot.org/uniprot/R4X0D0 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/758793:BRPE64_RS04225 ^@ http://purl.uniprot.org/uniprot/R4WG21 ^@ Similarity ^@ Belongs to the rubredoxin family. http://togogenome.org/gene/758793:BRPE64_RS31085 ^@ http://purl.uniprot.org/uniprot/A0A060PQV0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS26500 ^@ http://purl.uniprot.org/uniprot/R4WRQ3 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS16745 ^@ http://purl.uniprot.org/uniprot/R4X040 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).|||Homooctamer; tetramer of dimers.|||Reaction proceeds via a syn dehydration. http://togogenome.org/gene/758793:BRPE64_RS19735 ^@ http://purl.uniprot.org/uniprot/R4X2X4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS04470 ^@ http://purl.uniprot.org/uniprot/R4WUS6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon. http://togogenome.org/gene/758793:BRPE64_RS01485 ^@ http://purl.uniprot.org/uniprot/R4WF61 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/758793:BRPE64_RS11500 ^@ http://purl.uniprot.org/uniprot/R4WT45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/758793:BRPE64_RS29680 ^@ http://purl.uniprot.org/uniprot/R4WTT1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS13615 ^@ http://purl.uniprot.org/uniprot/R4WJD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS07310 ^@ http://purl.uniprot.org/uniprot/R4WQU5 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/758793:BRPE64_RS12910 ^@ http://purl.uniprot.org/uniprot/R4X0H9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS23740 ^@ http://purl.uniprot.org/uniprot/R4WQ17 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS00590 ^@ http://purl.uniprot.org/uniprot/R4WSM0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhC family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers. http://togogenome.org/gene/758793:BRPE64_RS30040 ^@ http://purl.uniprot.org/uniprot/R4WU22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AcsB/BcsB family.|||Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).|||Cell inner membrane|||Tightly associated with the cellulose synthase catalytic subunit. http://togogenome.org/gene/758793:BRPE64_RS14155 ^@ http://purl.uniprot.org/uniprot/R4WJM8 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/758793:BRPE64_RS25895 ^@ http://purl.uniprot.org/uniprot/R4X381 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS21845 ^@ http://purl.uniprot.org/uniprot/R4X3F6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS19945 ^@ http://purl.uniprot.org/uniprot/R4X2Z8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS31150 ^@ http://purl.uniprot.org/uniprot/A0A060PQW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS07980 ^@ http://purl.uniprot.org/uniprot/R4WR68 ^@ Function|||Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/758793:BRPE64_RS17610 ^@ http://purl.uniprot.org/uniprot/R4X261 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aromatic amine dehydrogenase light chain family.|||Heterotetramer of two light and two heavy chains.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS15765 ^@ http://purl.uniprot.org/uniprot/R4WKE7 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/758793:BRPE64_RS08755 ^@ http://purl.uniprot.org/uniprot/R4WHE9 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS17410 ^@ http://purl.uniprot.org/uniprot/R4WLC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS01475 ^@ http://purl.uniprot.org/uniprot/R4WVX5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/758793:BRPE64_RS23355 ^@ http://purl.uniprot.org/uniprot/R4WPQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS04170 ^@ http://purl.uniprot.org/uniprot/R4WFT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS17065 ^@ http://purl.uniprot.org/uniprot/R4X201 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/758793:BRPE64_RS07545 ^@ http://purl.uniprot.org/uniprot/R4WYM1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.|||This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. http://togogenome.org/gene/758793:BRPE64_RS02590 ^@ http://purl.uniprot.org/uniprot/R4WTU5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the homogentisate dioxygenase family.|||Hexamer; dimer of trimers.|||Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS09655 ^@ http://purl.uniprot.org/uniprot/R4WS55 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/758793:BRPE64_RS24315 ^@ http://purl.uniprot.org/uniprot/R4X3Z4 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/758793:BRPE64_RS29470 ^@ http://purl.uniprot.org/uniprot/R4X456 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS05045 ^@ http://purl.uniprot.org/uniprot/R4WXN5 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/758793:BRPE64_RS05345 ^@ http://purl.uniprot.org/uniprot/R4WG88 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/758793:BRPE64_RS06585 ^@ http://purl.uniprot.org/uniprot/R4WGU8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS26255 ^@ http://purl.uniprot.org/uniprot/R4X3B5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS18330 ^@ http://purl.uniprot.org/uniprot/R4X0K3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the precorrin methyltransferase family.|||Homodimer.|||Methylates precorrin-2 at the C-20 position to produce precorrin-3A. http://togogenome.org/gene/758793:BRPE64_RS05585 ^@ http://purl.uniprot.org/uniprot/R4WGB2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein bS18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS30175 ^@ http://purl.uniprot.org/uniprot/R4X4B4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NapB family.|||Binds 2 heme C groups per subunit.|||Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.|||Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS31610 ^@ http://purl.uniprot.org/uniprot/A0A060PKR6 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/758793:BRPE64_RS24290 ^@ http://purl.uniprot.org/uniprot/R4X3Z2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS13050 ^@ http://purl.uniprot.org/uniprot/R4WJ43 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/758793:BRPE64_RS12255 ^@ http://purl.uniprot.org/uniprot/R4WIU0 ^@ Function|||Similarity ^@ Belongs to the frataxin family.|||Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. http://togogenome.org/gene/758793:BRPE64_RS11745 ^@ http://purl.uniprot.org/uniprot/R4WT97 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/758793:BRPE64_RS17510 ^@ http://purl.uniprot.org/uniprot/R4WLD9 ^@ Cofactor|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/758793:BRPE64_RS10410 ^@ http://purl.uniprot.org/uniprot/R4WI45 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS00075 ^@ http://purl.uniprot.org/uniprot/R4WSC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS24050 ^@ http://purl.uniprot.org/uniprot/R4X2M5 ^@ Similarity ^@ Belongs to the GST superfamily. Omega family. http://togogenome.org/gene/758793:BRPE64_RS00275 ^@ http://purl.uniprot.org/uniprot/R4WEL7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. http://togogenome.org/gene/758793:BRPE64_RS23995 ^@ http://purl.uniprot.org/uniprot/R4WYY5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS07690 ^@ http://purl.uniprot.org/uniprot/R4WWN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/758793:BRPE64_RS02990 ^@ http://purl.uniprot.org/uniprot/R4WWW3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS23645 ^@ http://purl.uniprot.org/uniprot/R4WQ64 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/758793:BRPE64_RS02755 ^@ http://purl.uniprot.org/uniprot/R4WWR8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/758793:BRPE64_RS22080 ^@ http://purl.uniprot.org/uniprot/R4WY94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS13405 ^@ http://purl.uniprot.org/uniprot/R4WU59 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/758793:BRPE64_RS12650 ^@ http://purl.uniprot.org/uniprot/R4WIY3 ^@ Similarity ^@ Belongs to the malic enzymes family.|||In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/758793:BRPE64_RS22290 ^@ http://purl.uniprot.org/uniprot/R4X3J1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS13150 ^@ http://purl.uniprot.org/uniprot/R4WJ55 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family.|||Cell outer membrane|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/758793:BRPE64_RS09990 ^@ http://purl.uniprot.org/uniprot/R4WSA6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS16880 ^@ http://purl.uniprot.org/uniprot/R4WL49 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/758793:BRPE64_RS25180 ^@ http://purl.uniprot.org/uniprot/R4X311 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/758793:BRPE64_RS09845 ^@ http://purl.uniprot.org/uniprot/R4WS82 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/758793:BRPE64_RS20225 ^@ http://purl.uniprot.org/uniprot/R4X171 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Member of a two-component regulatory system. http://togogenome.org/gene/758793:BRPE64_RS20245 ^@ http://purl.uniprot.org/uniprot/R4WXK3 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/758793:BRPE64_RS08885 ^@ http://purl.uniprot.org/uniprot/R4WHG4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.|||Cell inner membrane|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/758793:BRPE64_RS09275 ^@ http://purl.uniprot.org/uniprot/R4WXD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS10915 ^@ http://purl.uniprot.org/uniprot/R4WIC4 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/758793:BRPE64_RS18755 ^@ http://purl.uniprot.org/uniprot/R4X2I1 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/758793:BRPE64_RS01235 ^@ http://purl.uniprot.org/uniprot/R4WMB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptA family.|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS05980 ^@ http://purl.uniprot.org/uniprot/R4WXZ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS27225 ^@ http://purl.uniprot.org/uniprot/R4X4P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS13645 ^@ http://purl.uniprot.org/uniprot/R4WYY0 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/758793:BRPE64_RS00935 ^@ http://purl.uniprot.org/uniprot/R4WM73 ^@ Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS15470 ^@ http://purl.uniprot.org/uniprot/R4WKH9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS18640 ^@ http://purl.uniprot.org/uniprot/R4X2H0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS21560 ^@ http://purl.uniprot.org/uniprot/R4X3D4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS08200 ^@ http://purl.uniprot.org/uniprot/R4WYU3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS09330 ^@ http://purl.uniprot.org/uniprot/R4WZ85 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/758793:BRPE64_RS18430 ^@ http://purl.uniprot.org/uniprot/R4WM49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS30890 ^@ http://purl.uniprot.org/uniprot/A0A060PKA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS26195 ^@ http://purl.uniprot.org/uniprot/R4WRU0 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS02725 ^@ http://purl.uniprot.org/uniprot/R4WTX0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/758793:BRPE64_RS16160 ^@ http://purl.uniprot.org/uniprot/R4X1M0 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/758793:BRPE64_RS23710 ^@ http://purl.uniprot.org/uniprot/R4X3V5 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.|||Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids. http://togogenome.org/gene/758793:BRPE64_RS05645 ^@ http://purl.uniprot.org/uniprot/R4WVG9 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/758793:BRPE64_RS07610 ^@ http://purl.uniprot.org/uniprot/R4WQZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/758793:BRPE64_RS28215 ^@ http://purl.uniprot.org/uniprot/R4X4X5 ^@ Similarity ^@ Belongs to the SIP oxidoreductase family. http://togogenome.org/gene/758793:BRPE64_RS06295 ^@ http://purl.uniprot.org/uniprot/R4WVT8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PriB family.|||Binds single-stranded DNA at the primosome assembly site (PAS).|||Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome. http://togogenome.org/gene/758793:BRPE64_RS10010 ^@ http://purl.uniprot.org/uniprot/R4WSB1 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/758793:BRPE64_RS30925 ^@ http://purl.uniprot.org/uniprot/A0A060PRA7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS08950 ^@ http://purl.uniprot.org/uniprot/R4WZ35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS05725 ^@ http://purl.uniprot.org/uniprot/R4WGC9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/758793:BRPE64_RS19835 ^@ http://purl.uniprot.org/uniprot/R4WXG6 ^@ Similarity ^@ Belongs to the ModE family. http://togogenome.org/gene/758793:BRPE64_RS07580 ^@ http://purl.uniprot.org/uniprot/R4WH62 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamB family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/758793:BRPE64_RS27310 ^@ http://purl.uniprot.org/uniprot/R4X4Q3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS23520 ^@ http://purl.uniprot.org/uniprot/R4X3T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS08460 ^@ http://purl.uniprot.org/uniprot/R4WYW6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/758793:BRPE64_RS08685 ^@ http://purl.uniprot.org/uniprot/R4WHI5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/758793:BRPE64_RS08025 ^@ http://purl.uniprot.org/uniprot/R4WWV0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/758793:BRPE64_RS29305 ^@ http://purl.uniprot.org/uniprot/R4WTH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS12085 ^@ http://purl.uniprot.org/uniprot/R4WIS1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS24910 ^@ http://purl.uniprot.org/uniprot/R4WQV3 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/758793:BRPE64_RS19820 ^@ http://purl.uniprot.org/uniprot/R4WXG3 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/758793:BRPE64_RS02785 ^@ http://purl.uniprot.org/uniprot/R4WFE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS25145 ^@ http://purl.uniprot.org/uniprot/R4WQQ5 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS06310 ^@ http://purl.uniprot.org/uniprot/R4WGR9 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/758793:BRPE64_RS01760 ^@ http://purl.uniprot.org/uniprot/R4WF17 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/758793:BRPE64_RS14420 ^@ http://purl.uniprot.org/uniprot/R4X150 ^@ Similarity ^@ Belongs to the terpene cyclase/mutase family. http://togogenome.org/gene/758793:BRPE64_RS29315 ^@ http://purl.uniprot.org/uniprot/R4X0X2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PqiA family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS22720 ^@ http://purl.uniprot.org/uniprot/R4WYF2 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/758793:BRPE64_RS29625 ^@ http://purl.uniprot.org/uniprot/R4X583 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS13155 ^@ http://purl.uniprot.org/uniprot/R4WJC3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/758793:BRPE64_RS00605 ^@ http://purl.uniprot.org/uniprot/R4WEX1 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/758793:BRPE64_RS20600 ^@ http://purl.uniprot.org/uniprot/R4WXQ4 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/758793:BRPE64_RS29455 ^@ http://purl.uniprot.org/uniprot/R4WTJ7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS06060 ^@ http://purl.uniprot.org/uniprot/R4WGP3 ^@ Similarity ^@ Belongs to the UPF0303 family. http://togogenome.org/gene/758793:BRPE64_RS30945 ^@ http://purl.uniprot.org/uniprot/A0A060PQR6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS16825 ^@ http://purl.uniprot.org/uniprot/R4X1X6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS09605 ^@ http://purl.uniprot.org/uniprot/R4WS50 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase E/G family. RNase E subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per homotetramer.|||Cell inner membrane|||Cytoplasm|||Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.|||Homotetramer formed by a dimer of dimers. http://togogenome.org/gene/758793:BRPE64_RS19040 ^@ http://purl.uniprot.org/uniprot/R4WX74 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS09440 ^@ http://purl.uniprot.org/uniprot/R4WS02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/758793:BRPE64_RS08625 ^@ http://purl.uniprot.org/uniprot/R4WRH6 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/758793:BRPE64_RS16385 ^@ http://purl.uniprot.org/uniprot/R4X1P7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS02780 ^@ http://purl.uniprot.org/uniprot/R4WWS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS08940 ^@ http://purl.uniprot.org/uniprot/R4WRP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS00915 ^@ http://purl.uniprot.org/uniprot/R4WST2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS24085 ^@ http://purl.uniprot.org/uniprot/R4WQH0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS09975 ^@ http://purl.uniprot.org/uniprot/R4WZG8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS11155 ^@ http://purl.uniprot.org/uniprot/R4WIG2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LptE lipoprotein family.|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.|||Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. http://togogenome.org/gene/758793:BRPE64_RS19705 ^@ http://purl.uniprot.org/uniprot/R4WXF2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/758793:BRPE64_RS06705 ^@ http://purl.uniprot.org/uniprot/R4WGV8 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/758793:BRPE64_RS11540 ^@ http://purl.uniprot.org/uniprot/R4X009 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapD family.|||Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.|||Cytoplasm|||Interacts with FtsZ. http://togogenome.org/gene/758793:BRPE64_RS22795 ^@ http://purl.uniprot.org/uniprot/R4X254 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell membrane|||Membrane|||Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter. http://togogenome.org/gene/758793:BRPE64_RS12820 ^@ http://purl.uniprot.org/uniprot/R4WJ72 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS12140 ^@ http://purl.uniprot.org/uniprot/R4WTJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/758793:BRPE64_RS27715 ^@ http://purl.uniprot.org/uniprot/R4WSF6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS13365 ^@ http://purl.uniprot.org/uniprot/R4X0M6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/758793:BRPE64_RS00190 ^@ http://purl.uniprot.org/uniprot/R4WSE8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS23035 ^@ http://purl.uniprot.org/uniprot/R4X3P6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS19120 ^@ http://purl.uniprot.org/uniprot/R4WMD1 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/758793:BRPE64_RS05830 ^@ http://purl.uniprot.org/uniprot/R4WPZ4 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/758793:BRPE64_RS03875 ^@ http://purl.uniprot.org/uniprot/R4WFY6 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/758793:BRPE64_RS29730 ^@ http://purl.uniprot.org/uniprot/R4WTU3 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/758793:BRPE64_RS18955 ^@ http://purl.uniprot.org/uniprot/R4WM65 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/758793:BRPE64_RS26850 ^@ http://purl.uniprot.org/uniprot/R4X4L1 ^@ Subunit ^@ Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/758793:BRPE64_RS12425 ^@ http://purl.uniprot.org/uniprot/R4WJ27 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/758793:BRPE64_RS00640 ^@ http://purl.uniprot.org/uniprot/R4WSN0 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/758793:BRPE64_RS06810 ^@ http://purl.uniprot.org/uniprot/R4WGW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS09915 ^@ http://purl.uniprot.org/uniprot/R4WHY4 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/758793:BRPE64_RS13445 ^@ http://purl.uniprot.org/uniprot/R4WU70 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS08180 ^@ http://purl.uniprot.org/uniprot/R4WH81 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/758793:BRPE64_RS23805 ^@ http://purl.uniprot.org/uniprot/R4X3V9 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/758793:BRPE64_RS26685 ^@ http://purl.uniprot.org/uniprot/R4X4J5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS10590 ^@ http://purl.uniprot.org/uniprot/R4WSM4 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/758793:BRPE64_RS27355 ^@ http://purl.uniprot.org/uniprot/R4X3L3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS12970 ^@ http://purl.uniprot.org/uniprot/R4WYP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS10820 ^@ http://purl.uniprot.org/uniprot/R4WSS0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/758793:BRPE64_RS09125 ^@ http://purl.uniprot.org/uniprot/R4WXB5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS16855 ^@ http://purl.uniprot.org/uniprot/R4WL47 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.|||Cell inner membrane http://togogenome.org/gene/758793:BRPE64_RS02145 ^@ http://purl.uniprot.org/uniprot/R4WTH2 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/758793:BRPE64_RS06725 ^@ http://purl.uniprot.org/uniprot/R4WGQ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyltransferase 20 family.|||Homotetramer.|||Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor. http://togogenome.org/gene/758793:BRPE64_RS03735 ^@ http://purl.uniprot.org/uniprot/R4WX56 ^@ Function ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate. http://togogenome.org/gene/758793:BRPE64_RS00090 ^@ http://purl.uniprot.org/uniprot/R4WEK4 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/758793:BRPE64_RS05660 ^@ http://purl.uniprot.org/uniprot/R4WGK1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M20A family. DapE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS27210 ^@ http://purl.uniprot.org/uniprot/R4WSA5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS25555 ^@ http://purl.uniprot.org/uniprot/R4WRC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS00490 ^@ http://purl.uniprot.org/uniprot/R4WEV7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AceK family.|||Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS13065 ^@ http://purl.uniprot.org/uniprot/R4WYQ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliH family.|||Cytoplasm|||Needed for flagellar regrowth and assembly. http://togogenome.org/gene/758793:BRPE64_RS15925 ^@ http://purl.uniprot.org/uniprot/R4WKI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS02650 ^@ http://purl.uniprot.org/uniprot/R4WFD5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS15740 ^@ http://purl.uniprot.org/uniprot/R4WKE2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS20575 ^@ http://purl.uniprot.org/uniprot/R4WXQ0 ^@ Function|||Similarity ^@ Belongs to the GMC oxidoreductase family.|||Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. http://togogenome.org/gene/758793:BRPE64_RS20700 ^@ http://purl.uniprot.org/uniprot/R4X1D6 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/758793:BRPE64_RS04250 ^@ http://purl.uniprot.org/uniprot/R4WG22 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS01160 ^@ http://purl.uniprot.org/uniprot/R4WSX7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/758793:BRPE64_RS03920 ^@ http://purl.uniprot.org/uniprot/R4WNT5 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/758793:BRPE64_RS06395 ^@ http://purl.uniprot.org/uniprot/R4WGL1 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/758793:BRPE64_RS23890 ^@ http://purl.uniprot.org/uniprot/R4WYX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS02075 ^@ http://purl.uniprot.org/uniprot/R4WW93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. RhlE subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA. http://togogenome.org/gene/758793:BRPE64_RS29545 ^@ http://purl.uniprot.org/uniprot/R4X462 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS23790 ^@ http://purl.uniprot.org/uniprot/R4WQC7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS01285 ^@ http://purl.uniprot.org/uniprot/R4WMC5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/758793:BRPE64_RS05715 ^@ http://purl.uniprot.org/uniprot/R4WVH9 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/758793:BRPE64_RS02290 ^@ http://purl.uniprot.org/uniprot/R4WTP3 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/758793:BRPE64_RS20645 ^@ http://purl.uniprot.org/uniprot/R4WNE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS25665 ^@ http://purl.uniprot.org/uniprot/R4X4B3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS02340 ^@ http://purl.uniprot.org/uniprot/R4WFA4 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/758793:BRPE64_RS16010 ^@ http://purl.uniprot.org/uniprot/R4WZR7 ^@ Similarity ^@ Belongs to the dihydropyrimidine dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS11285 ^@ http://purl.uniprot.org/uniprot/R4WY32 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/758793:BRPE64_RS06805 ^@ http://purl.uniprot.org/uniprot/R4WGR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS11170 ^@ http://purl.uniprot.org/uniprot/R4WZV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS00220 ^@ http://purl.uniprot.org/uniprot/R4WV82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS22740 ^@ http://purl.uniprot.org/uniprot/R4WYF5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS30020 ^@ http://purl.uniprot.org/uniprot/R4X160 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS21285 ^@ http://purl.uniprot.org/uniprot/R4WY02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS28675 ^@ http://purl.uniprot.org/uniprot/R4WT59 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/758793:BRPE64_RS07300 ^@ http://purl.uniprot.org/uniprot/R4WH01 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS22800 ^@ http://purl.uniprot.org/uniprot/R4X3N0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS13130 ^@ http://purl.uniprot.org/uniprot/R4WJB9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/758793:BRPE64_RS29670 ^@ http://purl.uniprot.org/uniprot/R4X587 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS02095 ^@ http://purl.uniprot.org/uniprot/R4WTG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS04010 ^@ http://purl.uniprot.org/uniprot/R4WG02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS10235 ^@ http://purl.uniprot.org/uniprot/R4WI24 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/758793:BRPE64_RS09255 ^@ http://purl.uniprot.org/uniprot/R4WZ78 ^@ Function ^@ Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals. http://togogenome.org/gene/758793:BRPE64_RS02355 ^@ http://purl.uniprot.org/uniprot/R4WTQ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/758793:BRPE64_RS02655 ^@ http://purl.uniprot.org/uniprot/R4WFM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAE transporter (TC 2.A.81) family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS15795 ^@ http://purl.uniprot.org/uniprot/R4WKP6 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/758793:BRPE64_RS25885 ^@ http://purl.uniprot.org/uniprot/R4WRK1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS17280 ^@ http://purl.uniprot.org/uniprot/R4WLJ6 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/758793:BRPE64_RS07015 ^@ http://purl.uniprot.org/uniprot/R4WW79 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS03020 ^@ http://purl.uniprot.org/uniprot/R4WFH0 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS09820 ^@ http://purl.uniprot.org/uniprot/R4WS80 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/758793:BRPE64_RS19275 ^@ http://purl.uniprot.org/uniprot/R4X0X5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS13410 ^@ http://purl.uniprot.org/uniprot/R4WYU8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/758793:BRPE64_RS12720 ^@ http://purl.uniprot.org/uniprot/R4WJ60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the high-potential iron-sulfur protein (HiPIP) family.|||Homodimer.|||Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria. http://togogenome.org/gene/758793:BRPE64_RS04790 ^@ http://purl.uniprot.org/uniprot/R4WV18 ^@ Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. ArgA subfamily.|||Cytoplasm|||In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role. http://togogenome.org/gene/758793:BRPE64_RS02840 ^@ http://purl.uniprot.org/uniprot/R4WNA9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS19720 ^@ http://purl.uniprot.org/uniprot/R4WMX6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/758793:BRPE64_RS16580 ^@ http://purl.uniprot.org/uniprot/R4WL58 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS14275 ^@ http://purl.uniprot.org/uniprot/R4WJP7 ^@ Caution|||Cofactor|||Similarity ^@ Belongs to the WrbA family.|||Binds 1 FMN per monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS05080 ^@ http://purl.uniprot.org/uniprot/R4WGD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS26875 ^@ http://purl.uniprot.org/uniprot/R4X4L3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS02055 ^@ http://purl.uniprot.org/uniprot/R4WF52 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/758793:BRPE64_RS28480 ^@ http://purl.uniprot.org/uniprot/R4X3X1 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/758793:BRPE64_RS12115 ^@ http://purl.uniprot.org/uniprot/R4WTJ1 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/758793:BRPE64_RS13425 ^@ http://purl.uniprot.org/uniprot/R4WJG5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS24890 ^@ http://purl.uniprot.org/uniprot/R4WZ79 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS01540 ^@ http://purl.uniprot.org/uniprot/R4WVY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS22560 ^@ http://purl.uniprot.org/uniprot/R4WPG0 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS07630 ^@ http://purl.uniprot.org/uniprot/R4WH67 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoS subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. http://togogenome.org/gene/758793:BRPE64_RS02730 ^@ http://purl.uniprot.org/uniprot/R4WWR5 ^@ Function|||Similarity ^@ Belongs to the ClpA/ClpB family.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK. http://togogenome.org/gene/758793:BRPE64_RS11165 ^@ http://purl.uniprot.org/uniprot/R4WY21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS08840 ^@ http://purl.uniprot.org/uniprot/R4WHK1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS19190 ^@ http://purl.uniprot.org/uniprot/R4WME2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS31025 ^@ http://purl.uniprot.org/uniprot/A0A060PGW9 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/758793:BRPE64_RS23695 ^@ http://purl.uniprot.org/uniprot/R4WQ77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS12460 ^@ http://purl.uniprot.org/uniprot/R4WTP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/758793:BRPE64_RS22115 ^@ http://purl.uniprot.org/uniprot/R4X3H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS12060 ^@ http://purl.uniprot.org/uniprot/R4WIR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS01425 ^@ http://purl.uniprot.org/uniprot/R4WVW5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC1 family. UbiB subfamily.|||Cell membrane|||Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS06305 ^@ http://purl.uniprot.org/uniprot/R4WGJ9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/758793:BRPE64_RS16630 ^@ http://purl.uniprot.org/uniprot/R4X010 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/758793:BRPE64_RS10140 ^@ http://purl.uniprot.org/uniprot/R4WSD7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/758793:BRPE64_RS12265 ^@ http://purl.uniprot.org/uniprot/R4WTK6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/758793:BRPE64_RS18915 ^@ http://purl.uniprot.org/uniprot/R4WX54 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS03095 ^@ http://purl.uniprot.org/uniprot/R4WFR4 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/758793:BRPE64_RS11315 ^@ http://purl.uniprot.org/uniprot/R4WZX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS22540 ^@ http://purl.uniprot.org/uniprot/R4WYD5 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/758793:BRPE64_RS00320 ^@ http://purl.uniprot.org/uniprot/R4WV98 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/758793:BRPE64_RS05220 ^@ http://purl.uniprot.org/uniprot/R4WG78 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/758793:BRPE64_RS09850 ^@ http://purl.uniprot.org/uniprot/R4WXL4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/758793:BRPE64_RS18665 ^@ http://purl.uniprot.org/uniprot/R4X2H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS22265 ^@ http://purl.uniprot.org/uniprot/R4X1Y5 ^@ Similarity ^@ Belongs to the PheA/TfdB FAD monooxygenase family. http://togogenome.org/gene/758793:BRPE64_RS16100 ^@ http://purl.uniprot.org/uniprot/R4WKW2 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS11765 ^@ http://purl.uniprot.org/uniprot/R4WTA3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS13390 ^@ http://purl.uniprot.org/uniprot/R4X0N0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS06365 ^@ http://purl.uniprot.org/uniprot/R4WVV0 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/758793:BRPE64_RS25715 ^@ http://purl.uniprot.org/uniprot/R4WR53 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS09840 ^@ http://purl.uniprot.org/uniprot/R4WHX7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/758793:BRPE64_RS17840 ^@ http://purl.uniprot.org/uniprot/R4WWI4 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/758793:BRPE64_RS00680 ^@ http://purl.uniprot.org/uniprot/R4WEX8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS03690 ^@ http://purl.uniprot.org/uniprot/R4WFW7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/758793:BRPE64_RS19805 ^@ http://purl.uniprot.org/uniprot/R4X2Y2 ^@ Similarity ^@ Belongs to the pseudomonas-type ThrB family. http://togogenome.org/gene/758793:BRPE64_RS07280 ^@ http://purl.uniprot.org/uniprot/R4WH31 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS22370 ^@ http://purl.uniprot.org/uniprot/R4WYC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS01050 ^@ http://purl.uniprot.org/uniprot/R4WES8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS23490 ^@ http://purl.uniprot.org/uniprot/R4WYR0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/758793:BRPE64_RS11640 ^@ http://purl.uniprot.org/uniprot/R4X020 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.|||Cell inner membrane http://togogenome.org/gene/758793:BRPE64_RS00880 ^@ http://purl.uniprot.org/uniprot/R4WF01 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/758793:BRPE64_RS10925 ^@ http://purl.uniprot.org/uniprot/R4WXZ4 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/758793:BRPE64_RS17845 ^@ http://purl.uniprot.org/uniprot/R4X0E8 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/758793:BRPE64_RS05385 ^@ http://purl.uniprot.org/uniprot/R4WVC0 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/758793:BRPE64_RS29140 ^@ http://purl.uniprot.org/uniprot/R4X539 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/758793:BRPE64_RS30300 ^@ http://purl.uniprot.org/uniprot/R4X5E0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS00155 ^@ http://purl.uniprot.org/uniprot/R4WLU3 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/758793:BRPE64_RS06795 ^@ http://purl.uniprot.org/uniprot/R4WW31 ^@ Similarity ^@ Belongs to the UPF0229 family. http://togogenome.org/gene/758793:BRPE64_RS09470 ^@ http://purl.uniprot.org/uniprot/R4WXG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/758793:BRPE64_RS03005 ^@ http://purl.uniprot.org/uniprot/R4WND7 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/758793:BRPE64_RS09265 ^@ http://purl.uniprot.org/uniprot/R4WHP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/758793:BRPE64_RS08385 ^@ http://purl.uniprot.org/uniprot/R4WX12 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/758793:BRPE64_RS15510 ^@ http://purl.uniprot.org/uniprot/R4X1F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS11145 ^@ http://purl.uniprot.org/uniprot/R4WZV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS28860 ^@ http://purl.uniprot.org/uniprot/R4X524 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/758793:BRPE64_RS31260 ^@ http://purl.uniprot.org/uniprot/A0A060PJG4 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/758793:BRPE64_RS25455 ^@ http://purl.uniprot.org/uniprot/R4X496 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/758793:BRPE64_RS14460 ^@ http://purl.uniprot.org/uniprot/R4WUV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS01520 ^@ http://purl.uniprot.org/uniprot/R4WVY2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS30210 ^@ http://purl.uniprot.org/uniprot/R4WU62 ^@ Similarity ^@ Belongs to the thioredoxin family. DsbE subfamily. http://togogenome.org/gene/758793:BRPE64_RS15020 ^@ http://purl.uniprot.org/uniprot/R4X1A4 ^@ Function|||Similarity ^@ Belongs to the PhnJ family.|||Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. http://togogenome.org/gene/758793:BRPE64_RS16310 ^@ http://purl.uniprot.org/uniprot/R4WZW3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 8 (cellulase D) family. http://togogenome.org/gene/758793:BRPE64_RS02610 ^@ http://purl.uniprot.org/uniprot/R4WN67 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS08410 ^@ http://purl.uniprot.org/uniprot/R4WYW0 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/758793:BRPE64_RS19390 ^@ http://purl.uniprot.org/uniprot/R4WXC3 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/758793:BRPE64_RS08650 ^@ http://purl.uniprot.org/uniprot/R4WYZ4 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/758793:BRPE64_RS13845 ^@ http://purl.uniprot.org/uniprot/R4WJN7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS21690 ^@ http://purl.uniprot.org/uniprot/R4WY60 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS13100 ^@ http://purl.uniprot.org/uniprot/R4WJ50 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliO/MopB family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS18250 ^@ http://purl.uniprot.org/uniprot/R4WWS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS27120 ^@ http://purl.uniprot.org/uniprot/R4X3J0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS17810 ^@ http://purl.uniprot.org/uniprot/R4WLI5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS02720 ^@ http://purl.uniprot.org/uniprot/R4WN87 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS25500 ^@ http://purl.uniprot.org/uniprot/R4X4A0 ^@ Similarity|||Subunit ^@ Belongs to the methylthioribose kinase family.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS24725 ^@ http://purl.uniprot.org/uniprot/R4WQR2 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/758793:BRPE64_RS19310 ^@ http://purl.uniprot.org/uniprot/R4X2S8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS17595 ^@ http://purl.uniprot.org/uniprot/R4WLP1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS12815 ^@ http://purl.uniprot.org/uniprot/R4WJ10 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS14340 ^@ http://purl.uniprot.org/uniprot/R4X123 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS03390 ^@ http://purl.uniprot.org/uniprot/R4WX24 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/758793:BRPE64_RS20360 ^@ http://purl.uniprot.org/uniprot/R4WMZ1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS12635 ^@ http://purl.uniprot.org/uniprot/R4WTR3 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/758793:BRPE64_RS08395 ^@ http://purl.uniprot.org/uniprot/R4WHF1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/758793:BRPE64_RS20125 ^@ http://purl.uniprot.org/uniprot/R4X317 ^@ Cofactor|||Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/758793:BRPE64_RS01765 ^@ http://purl.uniprot.org/uniprot/R4WF92 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/758793:BRPE64_RS06015 ^@ http://purl.uniprot.org/uniprot/R4WGN8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/758793:BRPE64_RS01675 ^@ http://purl.uniprot.org/uniprot/R4WF83 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/758793:BRPE64_RS07790 ^@ http://purl.uniprot.org/uniprot/R4WYQ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the R-transferase family. Bpt subfamily.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. http://togogenome.org/gene/758793:BRPE64_RS22965 ^@ http://purl.uniprot.org/uniprot/R4X276 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/758793:BRPE64_RS07405 ^@ http://purl.uniprot.org/uniprot/R4WH43 ^@ Similarity ^@ In the N-terminal section; belongs to the phytochrome family. http://togogenome.org/gene/758793:BRPE64_RS25480 ^@ http://purl.uniprot.org/uniprot/R4WQY8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS19250 ^@ http://purl.uniprot.org/uniprot/R4WXB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS05390 ^@ http://purl.uniprot.org/uniprot/R4WXS7 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/758793:BRPE64_RS02450 ^@ http://purl.uniprot.org/uniprot/R4WFB6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS20895 ^@ http://purl.uniprot.org/uniprot/R4X1G4 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS01855 ^@ http://purl.uniprot.org/uniprot/R4WMP6 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/758793:BRPE64_RS05555 ^@ http://purl.uniprot.org/uniprot/R4WVF1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS19755 ^@ http://purl.uniprot.org/uniprot/R4X122 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/758793:BRPE64_RS24170 ^@ http://purl.uniprot.org/uniprot/R4X2N4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS03040 ^@ http://purl.uniprot.org/uniprot/R4WFH1 ^@ PTM ^@ Binds 1 heme c group covalently per subunit. http://togogenome.org/gene/758793:BRPE64_RS09035 ^@ http://purl.uniprot.org/uniprot/R4WZ48 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/758793:BRPE64_RS00005 ^@ http://purl.uniprot.org/uniprot/R4WLS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/758793:BRPE64_RS08945 ^@ http://purl.uniprot.org/uniprot/R4WX87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS18630 ^@ http://purl.uniprot.org/uniprot/R4WX07 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS00430 ^@ http://purl.uniprot.org/uniprot/R4WVC1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS09495 ^@ http://purl.uniprot.org/uniprot/R4WXG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS24025 ^@ http://purl.uniprot.org/uniprot/R4X2M2 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/758793:BRPE64_RS07590 ^@ http://purl.uniprot.org/uniprot/R4WWL4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS01575 ^@ http://purl.uniprot.org/uniprot/R4WF74 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/758793:BRPE64_RS04195 ^@ http://purl.uniprot.org/uniprot/R4WFT9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS24450 ^@ http://purl.uniprot.org/uniprot/R4X2R4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS07440 ^@ http://purl.uniprot.org/uniprot/R4WWI7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS01175 ^@ http://purl.uniprot.org/uniprot/R4WVR5 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/758793:BRPE64_RS13005 ^@ http://purl.uniprot.org/uniprot/R4WJ36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS01880 ^@ http://purl.uniprot.org/uniprot/R4WMQ1 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/758793:BRPE64_RS05350 ^@ http://purl.uniprot.org/uniprot/R4WGG6 ^@ Cofactor|||Function ^@ Accepts electrons from ETF and reduces ubiquinone.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/758793:BRPE64_RS16375 ^@ http://purl.uniprot.org/uniprot/R4WVT5 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/758793:BRPE64_RS27850 ^@ http://purl.uniprot.org/uniprot/R4WSJ7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/758793:BRPE64_RS05805 ^@ http://purl.uniprot.org/uniprot/R4WGL5 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/758793:BRPE64_RS22420 ^@ http://purl.uniprot.org/uniprot/R4WYC6 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/758793:BRPE64_RS09545 ^@ http://purl.uniprot.org/uniprot/R4WZC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/758793:BRPE64_RS11660 ^@ http://purl.uniprot.org/uniprot/R4WY87 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COQ7 family.|||Binds 2 iron ions per subunit.|||Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS07010 ^@ http://purl.uniprot.org/uniprot/R4WGY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS25855 ^@ http://purl.uniprot.org/uniprot/R4WRA0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/758793:BRPE64_RS01260 ^@ http://purl.uniprot.org/uniprot/R4WMB9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS24160 ^@ http://purl.uniprot.org/uniprot/R4WQI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS17085 ^@ http://purl.uniprot.org/uniprot/R4X204 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS11235 ^@ http://purl.uniprot.org/uniprot/R4WY28 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/758793:BRPE64_RS18965 ^@ http://purl.uniprot.org/uniprot/R4WX61 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS05490 ^@ http://purl.uniprot.org/uniprot/R4WXT9 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/758793:BRPE64_RS13085 ^@ http://purl.uniprot.org/uniprot/R4WTZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS25930 ^@ http://purl.uniprot.org/uniprot/R4WRC0 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/758793:BRPE64_RS00010 ^@ http://purl.uniprot.org/uniprot/R4WSB8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/758793:BRPE64_RS05870 ^@ http://purl.uniprot.org/uniprot/R4WGE7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M15D family.|||Binds 1 zinc ion per subunit.|||Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. http://togogenome.org/gene/758793:BRPE64_RS29490 ^@ http://purl.uniprot.org/uniprot/R4X0Z4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/758793:BRPE64_RS28030 ^@ http://purl.uniprot.org/uniprot/R4WSU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS17795 ^@ http://purl.uniprot.org/uniprot/R4WWH6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell membrane|||Membrane|||Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter. http://togogenome.org/gene/758793:BRPE64_RS07445 ^@ http://purl.uniprot.org/uniprot/R4WYL0 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/758793:BRPE64_RS15350 ^@ http://purl.uniprot.org/uniprot/R4WV92 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/758793:BRPE64_RS09320 ^@ http://purl.uniprot.org/uniprot/R4WRX8 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/758793:BRPE64_RS05820 ^@ http://purl.uniprot.org/uniprot/R4WGE2 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/758793:BRPE64_RS12415 ^@ http://purl.uniprot.org/uniprot/R4X0C7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/758793:BRPE64_RS10045 ^@ http://purl.uniprot.org/uniprot/R4WHZ9 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/758793:BRPE64_RS22495 ^@ http://purl.uniprot.org/uniprot/R4X215 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS22570 ^@ http://purl.uniprot.org/uniprot/R4X224 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/758793:BRPE64_RS02150 ^@ http://purl.uniprot.org/uniprot/R4WF66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS30965 ^@ http://purl.uniprot.org/uniprot/A0A060PQS2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/758793:BRPE64_RS09925 ^@ http://purl.uniprot.org/uniprot/R4WZG2 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/758793:BRPE64_RS03815 ^@ http://purl.uniprot.org/uniprot/R4WFP8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. http://togogenome.org/gene/758793:BRPE64_RS00195 ^@ http://purl.uniprot.org/uniprot/R4WV76 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/758793:BRPE64_RS25775 ^@ http://purl.uniprot.org/uniprot/R4X368 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the malate synthase family. GlcB subfamily.|||Cytoplasm|||Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS06255 ^@ http://purl.uniprot.org/uniprot/R4WGJ4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS14455 ^@ http://purl.uniprot.org/uniprot/R4WK13 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS28620 ^@ http://purl.uniprot.org/uniprot/R4X0Q3 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/758793:BRPE64_RS01640 ^@ http://purl.uniprot.org/uniprot/R4WT58 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/758793:BRPE64_RS23955 ^@ http://purl.uniprot.org/uniprot/R4X3W6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS30845 ^@ http://purl.uniprot.org/uniprot/A0A060PR82 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS07685 ^@ http://purl.uniprot.org/uniprot/R4WR14 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/758793:BRPE64_RS20875 ^@ http://purl.uniprot.org/uniprot/R4X376 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/758793:BRPE64_RS00585 ^@ http://purl.uniprot.org/uniprot/R4WM13 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhD family.|||Cytoplasm|||Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.|||The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA. http://togogenome.org/gene/758793:BRPE64_RS07565 ^@ http://purl.uniprot.org/uniprot/R4WWK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/758793:BRPE64_RS10155 ^@ http://purl.uniprot.org/uniprot/R4WI15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS08505 ^@ http://purl.uniprot.org/uniprot/R4WX33 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/758793:BRPE64_RS22430 ^@ http://purl.uniprot.org/uniprot/R4X3K2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS13165 ^@ http://purl.uniprot.org/uniprot/R4WYS1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/758793:BRPE64_RS22095 ^@ http://purl.uniprot.org/uniprot/R4WNZ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/758793:BRPE64_RS12065 ^@ http://purl.uniprot.org/uniprot/R4WIY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS08695 ^@ http://purl.uniprot.org/uniprot/R4WX60 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS19115 ^@ http://purl.uniprot.org/uniprot/R4X2Q6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS07450 ^@ http://purl.uniprot.org/uniprot/R4WH10 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/758793:BRPE64_RS05610 ^@ http://purl.uniprot.org/uniprot/R4WGB4 ^@ Function|||Similarity ^@ Belongs to the Thz kinase family.|||Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). http://togogenome.org/gene/758793:BRPE64_RS05170 ^@ http://purl.uniprot.org/uniprot/R4WXP9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/758793:BRPE64_RS22580 ^@ http://purl.uniprot.org/uniprot/R4WP88 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS28385 ^@ http://purl.uniprot.org/uniprot/R4X3V4 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/758793:BRPE64_RS13610 ^@ http://purl.uniprot.org/uniprot/R4X0R4 ^@ Similarity ^@ Belongs to the GSP N family. http://togogenome.org/gene/758793:BRPE64_RS01090 ^@ http://purl.uniprot.org/uniprot/R4WVQ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PagL family.|||Cell outer membrane|||Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS27325 ^@ http://purl.uniprot.org/uniprot/R4X049 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS17380 ^@ http://purl.uniprot.org/uniprot/R4X238 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhC family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers. http://togogenome.org/gene/758793:BRPE64_RS15195 ^@ http://purl.uniprot.org/uniprot/R4WK37 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS21495 ^@ http://purl.uniprot.org/uniprot/R4WNR5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS07085 ^@ http://purl.uniprot.org/uniprot/R4WWC5 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/758793:BRPE64_RS01045 ^@ http://purl.uniprot.org/uniprot/R4WVP0 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/758793:BRPE64_RS08020 ^@ http://purl.uniprot.org/uniprot/R4WR77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/758793:BRPE64_RS05985 ^@ http://purl.uniprot.org/uniprot/R4WGG1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS12340 ^@ http://purl.uniprot.org/uniprot/R4WIU9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/758793:BRPE64_RS22200 ^@ http://purl.uniprot.org/uniprot/R4X1X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS15710 ^@ http://purl.uniprot.org/uniprot/R4WZN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS12330 ^@ http://purl.uniprot.org/uniprot/R4WYH6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/758793:BRPE64_RS09185 ^@ http://purl.uniprot.org/uniprot/R4WHK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS05420 ^@ http://purl.uniprot.org/uniprot/R4WG94 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/758793:BRPE64_RS22830 ^@ http://purl.uniprot.org/uniprot/R4WPD2 ^@ Similarity ^@ Belongs to the transketolase family. http://togogenome.org/gene/758793:BRPE64_RS04735 ^@ http://purl.uniprot.org/uniprot/R4WGA0 ^@ Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase class-III family. http://togogenome.org/gene/758793:BRPE64_RS08295 ^@ http://purl.uniprot.org/uniprot/R4WH93 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/758793:BRPE64_RS24815 ^@ http://purl.uniprot.org/uniprot/R4WQJ2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/758793:BRPE64_RS21275 ^@ http://purl.uniprot.org/uniprot/R4WNJ4 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/758793:BRPE64_RS19925 ^@ http://purl.uniprot.org/uniprot/R4WMR0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/758793:BRPE64_RS12465 ^@ http://purl.uniprot.org/uniprot/R4WIW4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS21680 ^@ http://purl.uniprot.org/uniprot/R4X3E3 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/758793:BRPE64_RS08590 ^@ http://purl.uniprot.org/uniprot/R4WYY3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS21485 ^@ http://purl.uniprot.org/uniprot/R4X1Q7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS10860 ^@ http://purl.uniprot.org/uniprot/R4WI53 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/758793:BRPE64_RS21610 ^@ http://purl.uniprot.org/uniprot/R4WNT3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS24520 ^@ http://purl.uniprot.org/uniprot/R4X2S4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS00905 ^@ http://purl.uniprot.org/uniprot/R4WF03 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/758793:BRPE64_RS04980 ^@ http://purl.uniprot.org/uniprot/R4WGC8 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/758793:BRPE64_RS31475 ^@ http://purl.uniprot.org/uniprot/A0A060PH65 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS23235 ^@ http://purl.uniprot.org/uniprot/R4WPX5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/758793:BRPE64_RS23285 ^@ http://purl.uniprot.org/uniprot/R4WPY6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS01825 ^@ http://purl.uniprot.org/uniprot/R4WF24 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/758793:BRPE64_RS24540 ^@ http://purl.uniprot.org/uniprot/R4X2S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS28510 ^@ http://purl.uniprot.org/uniprot/R4WT35 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS18800 ^@ http://purl.uniprot.org/uniprot/R4WX35 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS08740 ^@ http://purl.uniprot.org/uniprot/R4WRK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsB family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/758793:BRPE64_RS13015 ^@ http://purl.uniprot.org/uniprot/R4WTY5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS26770 ^@ http://purl.uniprot.org/uniprot/R4WZZ1 ^@ Similarity ^@ Belongs to the peptidase C59 family. http://togogenome.org/gene/758793:BRPE64_RS08000 ^@ http://purl.uniprot.org/uniprot/R4WWU5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS08790 ^@ http://purl.uniprot.org/uniprot/R4WX72 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/758793:BRPE64_RS11525 ^@ http://purl.uniprot.org/uniprot/R4WIM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS05835 ^@ http://purl.uniprot.org/uniprot/R4WVK3 ^@ Similarity ^@ Belongs to the UPF0125 (RnfH) family. http://togogenome.org/gene/758793:BRPE64_RS03970 ^@ http://purl.uniprot.org/uniprot/R4WNU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS06610 ^@ http://purl.uniprot.org/uniprot/R4WQD9 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/758793:BRPE64_RS05755 ^@ http://purl.uniprot.org/uniprot/R4WGL0 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS14435 ^@ http://purl.uniprot.org/uniprot/R4WUU7 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/758793:BRPE64_RS32150 ^@ http://purl.uniprot.org/uniprot/R4WTQ1 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/758793:BRPE64_RS27410 ^@ http://purl.uniprot.org/uniprot/R4X4R0 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. http://togogenome.org/gene/758793:BRPE64_RS25505 ^@ http://purl.uniprot.org/uniprot/R4WQZ4 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/758793:BRPE64_RS08330 ^@ http://purl.uniprot.org/uniprot/R4WRC7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS20045 ^@ http://purl.uniprot.org/uniprot/R4WXI0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/758793:BRPE64_RS14570 ^@ http://purl.uniprot.org/uniprot/R4X164 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS00785 ^@ http://purl.uniprot.org/uniprot/R4WEP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS10595 ^@ http://purl.uniprot.org/uniprot/R4WXV4 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/758793:BRPE64_RS29715 ^@ http://purl.uniprot.org/uniprot/R4X475 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS19845 ^@ http://purl.uniprot.org/uniprot/R4X2Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS06315 ^@ http://purl.uniprot.org/uniprot/R4WQ81 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/758793:BRPE64_RS20170 ^@ http://purl.uniprot.org/uniprot/R4WXJ3 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/758793:BRPE64_RS07595 ^@ http://purl.uniprot.org/uniprot/R4WYM7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/758793:BRPE64_RS00130 ^@ http://purl.uniprot.org/uniprot/R4WEK7 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/758793:BRPE64_RS09405 ^@ http://purl.uniprot.org/uniprot/R4WRZ7 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/758793:BRPE64_RS04700 ^@ http://purl.uniprot.org/uniprot/R4WXI7 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/758793:BRPE64_RS29390 ^@ http://purl.uniprot.org/uniprot/R4X0Y1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS05790 ^@ http://purl.uniprot.org/uniprot/R4WVJ3 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/758793:BRPE64_RS03240 ^@ http://purl.uniprot.org/uniprot/R4WFI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS14540 ^@ http://purl.uniprot.org/uniprot/R4WZB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS01150 ^@ http://purl.uniprot.org/uniprot/R4WF25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/758793:BRPE64_RS11880 ^@ http://purl.uniprot.org/uniprot/R4X062 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/758793:BRPE64_RS14125 ^@ http://purl.uniprot.org/uniprot/R4X0Y7 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/758793:BRPE64_RS01180 ^@ http://purl.uniprot.org/uniprot/R4WEU3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolB family.|||Cell outer membrane|||Membrane|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS07095 ^@ http://purl.uniprot.org/uniprot/R4WGY5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/758793:BRPE64_RS02105 ^@ http://purl.uniprot.org/uniprot/R4WF59 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/758793:BRPE64_RS28270 ^@ http://purl.uniprot.org/uniprot/R4WSV4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS09885 ^@ http://purl.uniprot.org/uniprot/R4WHT5 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/758793:BRPE64_RS09550 ^@ http://purl.uniprot.org/uniprot/R4WHQ3 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/758793:BRPE64_RS12455 ^@ http://purl.uniprot.org/uniprot/R4WTN6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/758793:BRPE64_RS06370 ^@ http://purl.uniprot.org/uniprot/R4WY40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS15645 ^@ http://purl.uniprot.org/uniprot/R4WKC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS24430 ^@ http://purl.uniprot.org/uniprot/R4WZ30 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS11650 ^@ http://purl.uniprot.org/uniprot/R4WIN9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/758793:BRPE64_RS15410 ^@ http://purl.uniprot.org/uniprot/R4X1E4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/758793:BRPE64_RS21515 ^@ http://purl.uniprot.org/uniprot/R4WNR9 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/758793:BRPE64_RS02490 ^@ http://purl.uniprot.org/uniprot/R4WTS9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/758793:BRPE64_RS29415 ^@ http://purl.uniprot.org/uniprot/R4X0Y5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS16060 ^@ http://purl.uniprot.org/uniprot/R4WVM3 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/758793:BRPE64_RS00890 ^@ http://purl.uniprot.org/uniprot/R4WSS6 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/758793:BRPE64_RS19745 ^@ http://purl.uniprot.org/uniprot/R4WMX8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/758793:BRPE64_RS06430 ^@ http://purl.uniprot.org/uniprot/R4WGL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS10215 ^@ http://purl.uniprot.org/uniprot/R4WSF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS23860 ^@ http://purl.uniprot.org/uniprot/R4WQD8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS07195 ^@ http://purl.uniprot.org/uniprot/R4WH22 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS13230 ^@ http://purl.uniprot.org/uniprot/R4WJD5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/758793:BRPE64_RS15250 ^@ http://purl.uniprot.org/uniprot/R4X1C8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the CoA-transferase III family. Frc subfamily.|||Homodimer.|||Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS07035 ^@ http://purl.uniprot.org/uniprot/R4WQN7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/758793:BRPE64_RS05760 ^@ http://purl.uniprot.org/uniprot/R4WPY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS01900 ^@ http://purl.uniprot.org/uniprot/R4WFB1 ^@ Similarity ^@ Belongs to the HSP15 family. http://togogenome.org/gene/758793:BRPE64_RS25460 ^@ http://purl.uniprot.org/uniprot/R4WQY0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KdgT transporter family.|||Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS14625 ^@ http://purl.uniprot.org/uniprot/R4X169 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS06460 ^@ http://purl.uniprot.org/uniprot/R4WGT6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS14760 ^@ http://purl.uniprot.org/uniprot/R4X179 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.|||One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/758793:BRPE64_RS30215 ^@ http://purl.uniprot.org/uniprot/R4X191 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/758793:BRPE64_RS26400 ^@ http://purl.uniprot.org/uniprot/R4X4H2 ^@ Cofactor ^@ Binds 3 heme c groups covalently per subunit. http://togogenome.org/gene/758793:BRPE64_RS17205 ^@ http://purl.uniprot.org/uniprot/R4X219 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS06390 ^@ http://purl.uniprot.org/uniprot/R4WY44 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS12510 ^@ http://purl.uniprot.org/uniprot/R4X0D9 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/758793:BRPE64_RS11940 ^@ http://purl.uniprot.org/uniprot/R4WIW5 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/758793:BRPE64_RS27870 ^@ http://purl.uniprot.org/uniprot/R4X4U8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/758793:BRPE64_RS13730 ^@ http://purl.uniprot.org/uniprot/R4WUD2 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/758793:BRPE64_RS06985 ^@ http://purl.uniprot.org/uniprot/R4WGX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS29805 ^@ http://purl.uniprot.org/uniprot/R4X132 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS02885 ^@ http://purl.uniprot.org/uniprot/R4WNB7 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/758793:BRPE64_RS28180 ^@ http://purl.uniprot.org/uniprot/R4X0H7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/758793:BRPE64_RS16925 ^@ http://purl.uniprot.org/uniprot/R4X1Y7 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/758793:BRPE64_RS09435 ^@ http://purl.uniprot.org/uniprot/R4WHR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS25070 ^@ http://purl.uniprot.org/uniprot/R4WQP4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS25285 ^@ http://purl.uniprot.org/uniprot/R4WR49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS08775 ^@ http://purl.uniprot.org/uniprot/R4WZ11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.|||Cell inner membrane|||Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.|||The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE). http://togogenome.org/gene/758793:BRPE64_RS03100 ^@ http://purl.uniprot.org/uniprot/R4WNF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS21830 ^@ http://purl.uniprot.org/uniprot/R4WP36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/758793:BRPE64_RS15220 ^@ http://purl.uniprot.org/uniprot/R4WK41 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS22160 ^@ http://purl.uniprot.org/uniprot/R4X3I0 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/758793:BRPE64_RS00670 ^@ http://purl.uniprot.org/uniprot/R4WVG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family.|||Periplasm http://togogenome.org/gene/758793:BRPE64_RS20375 ^@ http://purl.uniprot.org/uniprot/R4X336 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS18960 ^@ http://purl.uniprot.org/uniprot/R4WMF2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS02540 ^@ http://purl.uniprot.org/uniprot/R4WTT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS12480 ^@ http://purl.uniprot.org/uniprot/R4WYJ4 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/758793:BRPE64_RS14740 ^@ http://purl.uniprot.org/uniprot/R4WJW6 ^@ Similarity ^@ Belongs to the CbxX/CfxQ family. http://togogenome.org/gene/758793:BRPE64_RS11705 ^@ http://purl.uniprot.org/uniprot/R4X025 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/758793:BRPE64_RS08835 ^@ http://purl.uniprot.org/uniprot/R4WHF8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/758793:BRPE64_RS20920 ^@ http://purl.uniprot.org/uniprot/R4WXU9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/758793:BRPE64_RS10900 ^@ http://purl.uniprot.org/uniprot/R4WXZ1 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/758793:BRPE64_RS18105 ^@ http://purl.uniprot.org/uniprot/R4WLN8 ^@ Similarity ^@ Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. http://togogenome.org/gene/758793:BRPE64_RS06645 ^@ http://purl.uniprot.org/uniprot/R4WY86 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/758793:BRPE64_RS16290 ^@ http://purl.uniprot.org/uniprot/R4WVR7 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/758793:BRPE64_RS18075 ^@ http://purl.uniprot.org/uniprot/R4WWN5 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity ^@ Belongs to the globin family. Two-domain flavohemoproteins subfamily.|||Binds 1 FAD per subunit.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS03775 ^@ http://purl.uniprot.org/uniprot/R4WNQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS09775 ^@ http://purl.uniprot.org/uniprot/R4WHX0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS08170 ^@ http://purl.uniprot.org/uniprot/R4WWX5 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/758793:BRPE64_RS19000 ^@ http://purl.uniprot.org/uniprot/R4WM74 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/758793:BRPE64_RS09445 ^@ http://purl.uniprot.org/uniprot/R4WXG2 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 104 family.|||Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes. http://togogenome.org/gene/758793:BRPE64_RS14020 ^@ http://purl.uniprot.org/uniprot/R4WJK8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/758793:BRPE64_RS10050 ^@ http://purl.uniprot.org/uniprot/R4WSC0 ^@ Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.|||In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/758793:BRPE64_RS09875 ^@ http://purl.uniprot.org/uniprot/R4WXL7 ^@ Function|||Similarity ^@ Belongs to the DadA oxidoreductase family.|||Oxidative deamination of D-amino acids. http://togogenome.org/gene/758793:BRPE64_RS13205 ^@ http://purl.uniprot.org/uniprot/R4WJD1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/758793:BRPE64_RS08190 ^@ http://purl.uniprot.org/uniprot/R4WRA3 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/758793:BRPE64_RS26805 ^@ http://purl.uniprot.org/uniprot/R4X4K7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS11095 ^@ http://purl.uniprot.org/uniprot/R4WY16 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptD family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. http://togogenome.org/gene/758793:BRPE64_RS09950 ^@ http://purl.uniprot.org/uniprot/R4WZG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapB family.|||Cell inner membrane|||Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane. http://togogenome.org/gene/758793:BRPE64_RS28825 ^@ http://purl.uniprot.org/uniprot/R4WTC8 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/758793:BRPE64_RS01535 ^@ http://purl.uniprot.org/uniprot/R4WT41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS04245 ^@ http://purl.uniprot.org/uniprot/R4WFU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.|||Cell membrane|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/758793:BRPE64_RS13465 ^@ http://purl.uniprot.org/uniprot/R4WU75 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/758793:BRPE64_RS20785 ^@ http://purl.uniprot.org/uniprot/R4X369 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS26815 ^@ http://purl.uniprot.org/uniprot/R4WS33 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS32245 ^@ http://purl.uniprot.org/uniprot/R4WG92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0391 family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS22485 ^@ http://purl.uniprot.org/uniprot/R4WPE6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/758793:BRPE64_RS11465 ^@ http://purl.uniprot.org/uniprot/R4WIG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS32120 ^@ http://purl.uniprot.org/uniprot/R4X0J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0391 family.|||Cell membrane http://togogenome.org/gene/758793:BRPE64_RS14100 ^@ http://purl.uniprot.org/uniprot/R4X0Y3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/758793:BRPE64_RS12000 ^@ http://purl.uniprot.org/uniprot/R4WYE5 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/758793:BRPE64_RS26670 ^@ http://purl.uniprot.org/uniprot/R4WS12 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/758793:BRPE64_RS08635 ^@ http://purl.uniprot.org/uniprot/R4WHH9 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/758793:BRPE64_RS09155 ^@ http://purl.uniprot.org/uniprot/R4WZ65 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/758793:BRPE64_RS12430 ^@ http://purl.uniprot.org/uniprot/R4WTN2 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/758793:BRPE64_RS09560 ^@ http://purl.uniprot.org/uniprot/R4WS45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/758793:BRPE64_RS10750 ^@ http://purl.uniprot.org/uniprot/R4WI96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS22100 ^@ http://purl.uniprot.org/uniprot/R4WP82 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/758793:BRPE64_RS29170 ^@ http://purl.uniprot.org/uniprot/R4WTI0 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.|||Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids. http://togogenome.org/gene/758793:BRPE64_RS15325 ^@ http://purl.uniprot.org/uniprot/R4WK66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS33205 ^@ http://purl.uniprot.org/uniprot/R4WKS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fimbrial export usher family.|||Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/758793:BRPE64_RS28395 ^@ http://purl.uniprot.org/uniprot/R4WSY6 ^@ Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. http://togogenome.org/gene/758793:BRPE64_RS01685 ^@ http://purl.uniprot.org/uniprot/R4WT69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/758793:BRPE64_RS15800 ^@ http://purl.uniprot.org/uniprot/R4WVH7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS01190 ^@ http://purl.uniprot.org/uniprot/R4WMA9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS01920 ^@ http://purl.uniprot.org/uniprot/R4WMR3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/758793:BRPE64_RS18210 ^@ http://purl.uniprot.org/uniprot/R4X0J0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/758793:BRPE64_RS07795 ^@ http://purl.uniprot.org/uniprot/R4WH39 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/758793:BRPE64_RS00540 ^@ http://purl.uniprot.org/uniprot/R4WEW3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/758793:BRPE64_RS21955 ^@ http://purl.uniprot.org/uniprot/R4WP56 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/758793:BRPE64_RS21070 ^@ http://purl.uniprot.org/uniprot/R4WNN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/758793:BRPE64_RS02120 ^@ http://purl.uniprot.org/uniprot/R4WTG8 ^@ Function|||Similarity ^@ Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/758793:BRPE64_RS03345 ^@ http://purl.uniprot.org/uniprot/R4WNK0 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/758793:BRPE64_RS01410 ^@ http://purl.uniprot.org/uniprot/R4WF51 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/758793:BRPE64_RS22565 ^@ http://purl.uniprot.org/uniprot/R4WYD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS29370 ^@ http://purl.uniprot.org/uniprot/R4X448 ^@ Similarity ^@ Belongs to the AAE transporter (TC 2.A.81) family. http://togogenome.org/gene/758793:BRPE64_RS05190 ^@ http://purl.uniprot.org/uniprot/R4WXQ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/758793:BRPE64_RS23335 ^@ http://purl.uniprot.org/uniprot/R4WPZ3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family.