http://togogenome.org/gene/8478:NR3C1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR3 subfamily.|||Mitochondrion|||Nucleus|||centrosome|||spindle http://togogenome.org/gene/8478:CAMK2G ^@ http://purl.uniprot.org/uniprot/A0A8C3I6N2|||http://purl.uniprot.org/uniprot/A0A8C3I7H0|||http://purl.uniprot.org/uniprot/A0A8C3I8U1|||http://purl.uniprot.org/uniprot/A0A8C3PB13|||http://purl.uniprot.org/uniprot/A0A8C3PB15 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. http://togogenome.org/gene/8478:UTP14A ^@ http://purl.uniprot.org/uniprot/A0A8C3P328 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP14 family.|||nucleolus http://togogenome.org/gene/8478:TMEM45A ^@ http://purl.uniprot.org/uniprot/A0A8C3H6V8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM45 family.|||Membrane http://togogenome.org/gene/8478:SOSTDC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAY5 ^@ Caution|||Similarity ^@ Belongs to the sclerostin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:MLLT3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I171 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:SLC33A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:CENPL ^@ http://purl.uniprot.org/uniprot/A0A8C3HNH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CENP-L/IML3 family.|||Nucleus http://togogenome.org/gene/8478:E2F6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HK03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/8478:POLR1E ^@ http://purl.uniprot.org/uniprot/A0A8C3FPK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.|||nucleolus http://togogenome.org/gene/8478:FNIP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IM75|||http://purl.uniprot.org/uniprot/A0A8C3IN25|||http://purl.uniprot.org/uniprot/A0A8C3PE78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNIP family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/8478:MUL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IKF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:SH3BGRL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEZ3 ^@ Similarity ^@ Belongs to the SH3BGR family. http://togogenome.org/gene/8478:FGF23 ^@ http://purl.uniprot.org/uniprot/A0A8C3HAS3 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/8478:CCM2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HPT5 ^@ Similarity ^@ Belongs to the CCM2 family. http://togogenome.org/gene/8478:LEO1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IX57 ^@ Similarity ^@ Belongs to the LEO1 family. http://togogenome.org/gene/8478:HBS1L ^@ http://purl.uniprot.org/uniprot/A0A8C3HXA3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:LOC101932249 ^@ http://purl.uniprot.org/uniprot/A0A8C3I5M2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.|||Endoplasmic reticulum membrane|||Membrane|||Microsome membrane http://togogenome.org/gene/8478:SUSD6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAU4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:BCL7A ^@ http://purl.uniprot.org/uniprot/A0A8C3IT67 ^@ Similarity ^@ Belongs to the BCL7 family. http://togogenome.org/gene/8478:CER1 ^@ http://purl.uniprot.org/uniprot/A0A8C3INV9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DAN family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/8478:GORAB ^@ http://purl.uniprot.org/uniprot/A0A8C3HGI8 ^@ Similarity ^@ Belongs to the GORAB family. http://togogenome.org/gene/8478:SNX19 ^@ http://purl.uniprot.org/uniprot/A0A8C3PFD1 ^@ Similarity ^@ Belongs to the sorting nexin family. http://togogenome.org/gene/8478:NDUFAF7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).|||Belongs to the NDUFAF7 family.|||Mitochondrion http://togogenome.org/gene/8478:GABRA4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IZV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/8478:PTX3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZ60 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:RPL14 ^@ http://purl.uniprot.org/uniprot/A0A8C3IER9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL14 family. http://togogenome.org/gene/8478:STARD8 ^@ http://purl.uniprot.org/uniprot/A0A8C3FI71 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:LSM3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HM79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/8478:LZIC ^@ http://purl.uniprot.org/uniprot/A0A8C3IBN6 ^@ Similarity ^@ Belongs to the CTNNBIP1 family. http://togogenome.org/gene/8478:DBNDD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HJ88 ^@ Similarity ^@ Belongs to the dysbindin family. http://togogenome.org/gene/8478:CPEB4 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJL2|||http://purl.uniprot.org/uniprot/A0A8C3FJW2 ^@ Similarity ^@ Belongs to the RRM CPEB family. http://togogenome.org/gene/8478:CMPK2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKH2 ^@ Similarity ^@ Belongs to the thymidylate kinase family. http://togogenome.org/gene/8478:ACVR2B ^@ http://purl.uniprot.org/uniprot/A0A8C3P9F7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Membrane http://togogenome.org/gene/8478:VPS18 ^@ http://purl.uniprot.org/uniprot/A0A8C3HID8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS18 family.|||Membrane http://togogenome.org/gene/8478:GANAB ^@ http://purl.uniprot.org/uniprot/A0A8C3HY79 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/8478:HCRTR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IE30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:SLC29A4 ^@ http://purl.uniprot.org/uniprot/A0A8C3PB45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/8478:ERO1B ^@ http://purl.uniprot.org/uniprot/A0A8C3F998 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EROs family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/8478:ENPP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYI4 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/8478:SPDYC ^@ http://purl.uniprot.org/uniprot/A0A8C3PD37 ^@ Similarity ^@ Belongs to the Speedy/Ringo family. http://togogenome.org/gene/8478:ACTN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9R3|||http://purl.uniprot.org/uniprot/A0A8C3IAI1|||http://purl.uniprot.org/uniprot/A0A8C3IAJ5 ^@ Similarity ^@ Belongs to the alpha-actinin family. http://togogenome.org/gene/8478:SLX4 ^@ http://purl.uniprot.org/uniprot/A0A8C3ISD3 ^@ Similarity ^@ Belongs to the SLX4 family. http://togogenome.org/gene/8478:SLCO1A2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FWD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the organo anion transporter (TC 2.A.60) family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:RPS6 ^@ http://purl.uniprot.org/uniprot/A0A8C3P9W1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/8478:SERP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RAMP4 family.|||Endoplasmic reticulum membrane|||May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.|||Membrane http://togogenome.org/gene/8478:GREB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GREB1 family.|||Membrane http://togogenome.org/gene/8478:EMC8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHJ0 ^@ Similarity ^@ Belongs to the EMC8/EMC9 family. http://togogenome.org/gene/8478:LOC101939668 ^@ http://purl.uniprot.org/uniprot/A0A8C3FZR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tumor necrosis factor family.|||Membrane|||Secreted http://togogenome.org/gene/8478:PEX3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVR9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Interacts with PEX19.|||Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.|||Peroxisome membrane http://togogenome.org/gene/8478:LOC101942618 ^@ http://purl.uniprot.org/uniprot/A0A8C3I568 ^@ Function|||Similarity ^@ Belongs to the phytoene/squalene synthase family.|||Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. http://togogenome.org/gene/8478:STMN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FHX7 ^@ Similarity ^@ Belongs to the stathmin family. http://togogenome.org/gene/8478:FSCN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9I1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fascin family.|||cytoskeleton http://togogenome.org/gene/8478:LOC101944980 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7U5|||http://purl.uniprot.org/uniprot/A0A8C3I9A1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.|||Endoplasmic reticulum membrane|||Microsome membrane http://togogenome.org/gene/8478:DACT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PE07 ^@ Similarity ^@ Belongs to the dapper family. http://togogenome.org/gene/8478:VPS51 ^@ http://purl.uniprot.org/uniprot/A0A8C3IG76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the VPS51 family.|||Component of the Golgi-associated retrograde protein (GARP) complex. Component of the endosome-associated retrograde protein (EARP) complex.|||Endosome|||Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.|||Recycling endosome|||trans-Golgi network http://togogenome.org/gene/8478:GAB3 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1E8 ^@ Similarity ^@ Belongs to the GAB family. http://togogenome.org/gene/8478:TCIRG1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P8H4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.|||Membrane http://togogenome.org/gene/8478:GDF7 ^@ http://purl.uniprot.org/uniprot/A0A8C3I4J1 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/8478:EMC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJ31 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC1 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:IL10 ^@ http://purl.uniprot.org/uniprot/A0A8C3H5R0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IL-10 family.|||Immune regulatory cytokine.|||Secreted http://togogenome.org/gene/8478:SNX32 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGA5 ^@ Function|||Similarity ^@ Belongs to the sorting nexin family.|||Involved in several stages of intracellular trafficking. http://togogenome.org/gene/8478:MRTO4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHI1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with the pre-60S ribosomal particle.|||Belongs to the universal ribosomal protein uL10 family.|||Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.|||Cytoplasm|||nucleolus http://togogenome.org/gene/8478:RMND1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P890 ^@ Similarity ^@ Belongs to the RMD1/sif2 family. http://togogenome.org/gene/8478:BSX ^@ http://purl.uniprot.org/uniprot/A0A8C3HNU5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:EAF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCI1 ^@ Similarity ^@ Belongs to the EAF family. http://togogenome.org/gene/8478:NDUFB3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCC4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB3 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:ETV5 ^@ http://purl.uniprot.org/uniprot/A0A8C3FIB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/8478:LOC101950931 ^@ http://purl.uniprot.org/uniprot/A0A8C3HBG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/8478:STX17 ^@ http://purl.uniprot.org/uniprot/A0A8C3H5J0 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/8478:LOC101950830 ^@ http://purl.uniprot.org/uniprot/A0A8C3FSU2 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/8478:TMEFF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F5T4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:TADA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F7C7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TADA1 family.|||Nucleus|||Probably involved in transcriptional regulation. http://togogenome.org/gene/8478:TLN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HXH8 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/8478:UBIAD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Membrane http://togogenome.org/gene/8478:RNF111 ^@ http://purl.uniprot.org/uniprot/A0A8C3FXH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Arkadia family.|||PML body http://togogenome.org/gene/8478:C2H5orf22 ^@ http://purl.uniprot.org/uniprot/A0A8C3H503 ^@ Similarity ^@ Belongs to the UPF0489 family. http://togogenome.org/gene/8478:TSPAN12 ^@ http://purl.uniprot.org/uniprot/A0A8C3FPV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/8478:SEPTIN6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IA11 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/8478:CCNT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FSU9|||http://purl.uniprot.org/uniprot/A0A8C3HB57 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/8478:LOC101946689 ^@ http://purl.uniprot.org/uniprot/A0A8C3I1F7|||http://purl.uniprot.org/uniprot/A0A8C3P9X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat Groucho/TLE family.|||Nucleus http://togogenome.org/gene/8478:P2RY4 ^@ http://purl.uniprot.org/uniprot/A0A8C3P6U0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:FZD10 ^@ http://purl.uniprot.org/uniprot/A0A8C3ILG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Membrane http://togogenome.org/gene/8478:UBE3D ^@ http://purl.uniprot.org/uniprot/A0A8C3IIF3 ^@ Function ^@ E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. http://togogenome.org/gene/8478:HIBADH ^@ http://purl.uniprot.org/uniprot/A0A8C3IDU8 ^@ Similarity ^@ Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily. http://togogenome.org/gene/8478:SCN1B ^@ http://purl.uniprot.org/uniprot/A0A8C3FKT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:LOC101938578 ^@ http://purl.uniprot.org/uniprot/A0A8C3FIS0 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/8478:IL18R1 ^@ http://purl.uniprot.org/uniprot/A0A8C3H8U1 ^@ Similarity ^@ Belongs to the interleukin-1 receptor family. http://togogenome.org/gene/8478:RAB11FIP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3ILE3|||http://purl.uniprot.org/uniprot/A0A8C3PE18 ^@ Subcellular Location Annotation ^@ Cleavage furrow|||Endosome membrane|||Membrane|||Midbody|||Recycling endosome membrane http://togogenome.org/gene/8478:PKM ^@ http://purl.uniprot.org/uniprot/A0A8C3FGN8 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/8478:DGKG ^@ http://purl.uniprot.org/uniprot/A0A8C3FNJ7|||http://purl.uniprot.org/uniprot/A0A8C3H985 ^@ Similarity ^@ Belongs to the eukaryotic diacylglycerol kinase family. http://togogenome.org/gene/8478:SLC25A25 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMM5|||http://purl.uniprot.org/uniprot/A0A8C3IMT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/8478:FAM120A ^@ http://purl.uniprot.org/uniprot/A0A8C3I3Q0|||http://purl.uniprot.org/uniprot/A0A8C3I6J8 ^@ Similarity ^@ Belongs to the constitutive coactivator of PPAR-gamma family. http://togogenome.org/gene/8478:ST8SIA3 ^@ http://purl.uniprot.org/uniprot/A0A8C3ISJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/8478:RBM22 ^@ http://purl.uniprot.org/uniprot/A0A8C3FU74|||http://purl.uniprot.org/uniprot/A0A8C3HAL5 ^@ Similarity ^@ Belongs to the SLT11 family. http://togogenome.org/gene/8478:LOC101940098 ^@ http://purl.uniprot.org/uniprot/A0A8C3FRV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/8478:LOC101953600 ^@ http://purl.uniprot.org/uniprot/A0A8C3HQW0 ^@ Similarity ^@ Belongs to the SELO family. http://togogenome.org/gene/8478:KIF25 ^@ http://purl.uniprot.org/uniprot/A0A8C3HER2 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/8478:LOC101939802 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDP6 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/8478:EXOG ^@ http://purl.uniprot.org/uniprot/A0A8C3HYW6 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/8478:ZDHHC24 ^@ http://purl.uniprot.org/uniprot/A0A8C3PD90 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/8478:SLC19A2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F9B3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.|||Cell membrane|||High-affinity transporter for the intake of thiamine. http://togogenome.org/gene/8478:LOC101948784 ^@ http://purl.uniprot.org/uniprot/A0A8C3FE16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:LOC101933582 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9D4|||http://purl.uniprot.org/uniprot/A0A8C3IBJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C26 family.|||extracellular space http://togogenome.org/gene/8478:NUS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I242 ^@ Similarity ^@ Belongs to the UPP synthase family. http://togogenome.org/gene/8478:LOC101953301 ^@ http://purl.uniprot.org/uniprot/A0A8C3I430 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/8478:ADRA1B ^@ http://purl.uniprot.org/uniprot/A0A8C3FKD0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Cytoplasm|||Membrane|||This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.|||caveola http://togogenome.org/gene/8478:LOC101933933 ^@ http://purl.uniprot.org/uniprot/A0A8C3ITQ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:LOC101951632 ^@ http://purl.uniprot.org/uniprot/A0A8C3IIK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:VAMP4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Membrane http://togogenome.org/gene/8478:SNAP47 ^@ http://purl.uniprot.org/uniprot/A0A8C3F478 ^@ Similarity ^@ Belongs to the SVAP1 family. http://togogenome.org/gene/8478:NFE2L3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IF99 ^@ Similarity ^@ Belongs to the bZIP family. CNC subfamily. http://togogenome.org/gene/8478:EDA ^@ http://purl.uniprot.org/uniprot/A0A8C3HLU1 ^@ Similarity ^@ Belongs to the tumor necrosis factor family. http://togogenome.org/gene/8478:HMGCLL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICG2 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/8478:STOM ^@ http://purl.uniprot.org/uniprot/A0A8C3FRQ9 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/8478:MAP1LC3C ^@ http://purl.uniprot.org/uniprot/A0A8C3FMX4 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/8478:NETO2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRR1|||http://purl.uniprot.org/uniprot/A0A8C3HSK0|||http://purl.uniprot.org/uniprot/A0A8C3P7Z2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:MMGT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQD7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane magnesium transporter (TC 1.A.67) family.|||Early endosome membrane|||Endosome membrane|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport. http://togogenome.org/gene/8478:RPGRIP1L ^@ http://purl.uniprot.org/uniprot/A0A8C3HDV3 ^@ Similarity ^@ Belongs to the RPGRIP1 family. http://togogenome.org/gene/8478:LOC101952859 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRK3 ^@ Similarity ^@ Belongs to the AKAP110 family. http://togogenome.org/gene/8478:IL4R ^@ http://purl.uniprot.org/uniprot/A0A8C3F837 ^@ Function|||Similarity ^@ Belongs to the type I cytokine receptor family. Type 4 subfamily.|||Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. http://togogenome.org/gene/8478:CPT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H4X3 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/8478:PDIA4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein disulfide isomerase family.|||Endoplasmic reticulum lumen http://togogenome.org/gene/8478:SEMA3F ^@ http://purl.uniprot.org/uniprot/A0A8C3F5K3|||http://purl.uniprot.org/uniprot/A0A8C3H6J8 ^@ Caution|||Similarity ^@ Belongs to the semaphorin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:SSR3 ^@ http://purl.uniprot.org/uniprot/A0A8C3P9I6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-gamma family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/8478:DMRT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IP57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DMRT family.|||Nucleus http://togogenome.org/gene/8478:MTFR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HX61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MTFR1 family.|||Mitochondrion|||Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission. http://togogenome.org/gene/8478:LIN9 ^@ http://purl.uniprot.org/uniprot/A0A8C3HD12|||http://purl.uniprot.org/uniprot/A0A8C3HD15 ^@ Similarity ^@ Belongs to the lin-9 family. http://togogenome.org/gene/8478:TMX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUU8 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/8478:DYNLT5 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1F5 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/8478:CAMK1G ^@ http://purl.uniprot.org/uniprot/A0A8C3PBH4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:TBXAS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HHW6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/8478:FEZ2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHC3|||http://purl.uniprot.org/uniprot/A0A8C3IJN0 ^@ Similarity ^@ Belongs to the zygin family. http://togogenome.org/gene/8478:CSRNP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AXUD1 family.|||Nucleus http://togogenome.org/gene/8478:MYF6 ^@ http://purl.uniprot.org/uniprot/A0A8C3F2K5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:PARP11 ^@ http://purl.uniprot.org/uniprot/A0A8C3FRY6|||http://purl.uniprot.org/uniprot/A0A8C3FUE9 ^@ Similarity ^@ Belongs to the ARTD/PARP family. http://togogenome.org/gene/8478:ONECUT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/8478:NMUR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FST8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for the neuromedin-U and neuromedin-S neuropeptides. http://togogenome.org/gene/8478:LETMD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZQ9 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/8478:GHRHR ^@ http://purl.uniprot.org/uniprot/A0A8C3H749 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:MAP4K3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFZ2|||http://purl.uniprot.org/uniprot/A0A8C3IJA5 ^@ Function|||Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.|||May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. http://togogenome.org/gene/8478:BTF3L4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKZ6 ^@ Similarity ^@ Belongs to the NAC-beta family. http://togogenome.org/gene/8478:FGF4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCQ2 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/8478:PANX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8X8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||Structural component of the gap junctions and the hemichannels.|||gap junction http://togogenome.org/gene/8478:SERPINI2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRZ2 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/8478:KLC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IF50 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the kinesin light chain family.|||Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.|||Oligomeric complex composed of two heavy chains and two light chains.|||cytoskeleton http://togogenome.org/gene/8478:ASPH ^@ http://purl.uniprot.org/uniprot/A0A8C3IA39|||http://purl.uniprot.org/uniprot/A0A8C3IA50|||http://purl.uniprot.org/uniprot/A0A8C3IBK1|||http://purl.uniprot.org/uniprot/A0A8C3IBP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartyl/asparaginyl beta-hydroxylase family.|||Membrane http://togogenome.org/gene/8478:LOC101954181 ^@ http://purl.uniprot.org/uniprot/A0A8C3FC61 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/8478:MAN1A2 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZZ1|||http://purl.uniprot.org/uniprot/A0A8C3F090 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 47 family. http://togogenome.org/gene/8478:SIAH2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P9S0 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/8478:MCM6 ^@ http://purl.uniprot.org/uniprot/A0A8C3FVQ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/8478:COQ8A ^@ http://purl.uniprot.org/uniprot/A0A8C3P2U3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family. http://togogenome.org/gene/8478:FGF3 ^@ http://purl.uniprot.org/uniprot/A0A8C3P2I7 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/8478:SPATS2L ^@ http://purl.uniprot.org/uniprot/A0A8C3HCN6 ^@ Similarity ^@ Belongs to the SPATS2 family. http://togogenome.org/gene/8478:GFM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I0L0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.|||Mitochondrion http://togogenome.org/gene/8478:LOC101933863 ^@ http://purl.uniprot.org/uniprot/A0A8C3P7Z6 ^@ Similarity ^@ Belongs to the multicopper oxidase family. http://togogenome.org/gene/8478:A4GALT ^@ http://purl.uniprot.org/uniprot/A0A8C3IMB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 32 family.|||Golgi apparatus membrane http://togogenome.org/gene/8478:TSPAN18 ^@ http://purl.uniprot.org/uniprot/A0A8C3HF66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/8478:CANX ^@ http://purl.uniprot.org/uniprot/A0A8C3FRD6 ^@ Similarity ^@ Belongs to the calreticulin family. http://togogenome.org/gene/8478:VTA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HXN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VTA1 family.|||Cytoplasm|||Endosome membrane|||Membrane http://togogenome.org/gene/8478:LOC101949585 ^@ http://purl.uniprot.org/uniprot/A0A8C3INE0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:VHL ^@ http://purl.uniprot.org/uniprot/A0A8C3HMC9 ^@ Similarity ^@ Belongs to the VHL family. http://togogenome.org/gene/8478:IRF6 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8W7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:HDDC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I0B5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HDDC2 family.|||Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).|||Homodimer. http://togogenome.org/gene/8478:STRN ^@ http://purl.uniprot.org/uniprot/A0A8C3IIQ7|||http://purl.uniprot.org/uniprot/A0A8C3IIQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat striatin family.|||Membrane http://togogenome.org/gene/8478:SCD ^@ http://purl.uniprot.org/uniprot/A0A8C3I6H4 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/8478:JPH1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FHG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the junctophilin family.|||Cell membrane|||Endoplasmic reticulum membrane|||Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.|||Membrane http://togogenome.org/gene/8478:NPTX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I5E6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:NR4A3 ^@ http://purl.uniprot.org/uniprot/A0A8C3F774 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/8478:CORO7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IU55 ^@ Similarity ^@ Belongs to the WD repeat coronin family. http://togogenome.org/gene/8478:LOC101934351 ^@ http://purl.uniprot.org/uniprot/A0A8C3H576 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin family. SUMO subfamily.|||Nucleus http://togogenome.org/gene/8478:EPHA4 ^@ http://purl.uniprot.org/uniprot/A0A8C3I446 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome|||Membrane http://togogenome.org/gene/8478:SLC37A3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Membrane http://togogenome.org/gene/8478:UNKL ^@ http://purl.uniprot.org/uniprot/A0A8C3F771 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unkempt family.|||Cytoplasm http://togogenome.org/gene/8478:LOC101944783 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYC8 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/8478:C2H18orf21 ^@ http://purl.uniprot.org/uniprot/A0A8C3H6D3 ^@ Similarity ^@ Belongs to the UPF0711 family. http://togogenome.org/gene/8478:CTNND1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUV3 ^@ Similarity ^@ Belongs to the beta-catenin family. http://togogenome.org/gene/8478:EPC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUN4|||http://purl.uniprot.org/uniprot/A0A8C3HUQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the enhancer of polycomb family.|||Nucleus http://togogenome.org/gene/8478:CRELD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8J2 ^@ Caution|||Similarity ^@ Belongs to the CRELD family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:CIBAR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PD15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CIBAR family.|||centriole http://togogenome.org/gene/8478:ANKRD13C ^@ http://purl.uniprot.org/uniprot/A0A8C3PC99 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:C4H6orf89 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEB4 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:OPN5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/8478:LOC101938654 ^@ http://purl.uniprot.org/uniprot/A0A8C3FRK3 ^@ Function|||Similarity ^@ Belongs to the alpha-carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/8478:GJA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I083 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family. Alpha-type (group II) subfamily.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/8478:LOC101942784 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHX9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family. http://togogenome.org/gene/8478:AACS ^@ http://purl.uniprot.org/uniprot/A0A8C3INU1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP-dependent AMP-binding enzyme family.|||Converts acetoacetate to acetoacetyl-CoA in the cytosol.|||cytosol http://togogenome.org/gene/8478:STAM ^@ http://purl.uniprot.org/uniprot/A0A8C3HND4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STAM family.|||Early endosome membrane http://togogenome.org/gene/8478:EVX1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDU3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:CDKN2AIPNL ^@ http://purl.uniprot.org/uniprot/A0A8C3FJJ4 ^@ Similarity ^@ Belongs to the CARF family. http://togogenome.org/gene/8478:LOC101932491 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/8478:TJP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3INU0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane|||tight junction http://togogenome.org/gene/8478:APPL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HE40 ^@ Subcellular Location Annotation ^@ Early endosome membrane|||Endosome membrane|||Membrane|||Nucleus|||phagosome|||ruffle http://togogenome.org/gene/8478:CNOT8 ^@ http://purl.uniprot.org/uniprot/A0A8C3F3I4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAF1 family.|||Nucleus http://togogenome.org/gene/8478:TNFAIP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYV0 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/8478:USB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUA8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 2H phosphoesterase superfamily. USB1 family.|||Nucleus|||Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA. http://togogenome.org/gene/8478:LOC101934873 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRN1 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:NR5A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IX01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR5 subfamily.|||Nucleus http://togogenome.org/gene/8478:DYM ^@ http://purl.uniprot.org/uniprot/A0A8C3IPY2|||http://purl.uniprot.org/uniprot/A0A8C3PEK9 ^@ Similarity ^@ Belongs to the dymeclin family. http://togogenome.org/gene/8478:HSPA9 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBF2 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/8478:EXTL3 ^@ http://purl.uniprot.org/uniprot/A0A8C3PAH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 47 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/8478:PARVG ^@ http://purl.uniprot.org/uniprot/A0A8C3IMR7|||http://purl.uniprot.org/uniprot/A0A8C3INL4 ^@ Similarity ^@ Belongs to the parvin family. http://togogenome.org/gene/8478:NDUFS8 ^@ http://purl.uniprot.org/uniprot/A0A8C3HV95 ^@ Similarity ^@ Belongs to the complex I 23 kDa subunit family. http://togogenome.org/gene/8478:MKX ^@ http://purl.uniprot.org/uniprot/A0A8C3HRL7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:GABRG1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IX68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/8478:GABRA6 ^@ http://purl.uniprot.org/uniprot/A0A8C3FLV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/8478:FAM3C ^@ http://purl.uniprot.org/uniprot/A0A8C3FLD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM3 family.|||Secreted http://togogenome.org/gene/8478:NDUFB4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F4F6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB4 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:ZDHHC9 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDA4 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/8478:DDC ^@ http://purl.uniprot.org/uniprot/A0A8C3P881 ^@ Similarity|||Subunit ^@ Belongs to the group II decarboxylase family.|||Homodimer. http://togogenome.org/gene/8478:LOC101940193 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMR0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SCAR/WAVE family.|||Binds actin and the Arp2/3 complex.|||Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.|||cytoskeleton http://togogenome.org/gene/8478:KDM4A ^@ http://purl.uniprot.org/uniprot/A0A8C3F6W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the JHDM3 histone demethylase family.|||Nucleus http://togogenome.org/gene/8478:SENP6 ^@ http://purl.uniprot.org/uniprot/A0A8C3II16|||http://purl.uniprot.org/uniprot/A0A8C3II26|||http://purl.uniprot.org/uniprot/A0A8C3IIU3 ^@ Similarity ^@ Belongs to the peptidase C48 family. http://togogenome.org/gene/8478:DARS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FSJ0 ^@ Function|||Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. http://togogenome.org/gene/8478:WARS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1K2 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/8478:HESX1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P3Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ANF homeobox family.|||Nucleus http://togogenome.org/gene/8478:ESRRG ^@ http://purl.uniprot.org/uniprot/A0A8C3P551|||http://purl.uniprot.org/uniprot/A0A8C3P559 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR3 subfamily.|||Nucleus http://togogenome.org/gene/8478:MFN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IWE4 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/8478:NDUFAF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HIL2 ^@ Function|||Similarity ^@ As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.|||Belongs to the CIA30 family. http://togogenome.org/gene/8478:VPS29 ^@ http://purl.uniprot.org/uniprot/A0A8C3H6U1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.|||Belongs to the VPS29 family.|||Endosome membrane http://togogenome.org/gene/8478:ABCB10 ^@ http://purl.uniprot.org/uniprot/A0A8C3H8H6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:GNB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCL5 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/8478:GRK3 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBP4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. http://togogenome.org/gene/8478:SLC16A2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P755 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:CCNJL ^@ http://purl.uniprot.org/uniprot/A0A8C3FSW9 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/8478:LOC101946412 ^@ http://purl.uniprot.org/uniprot/A0A8C3P9L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the argonaute family.|||P-body http://togogenome.org/gene/8478:GTF2A2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVQ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIA subunit 2 family.|||Nucleus|||TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. http://togogenome.org/gene/8478:MOV10 ^@ http://purl.uniprot.org/uniprot/A0A8C3I0W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.|||P-body http://togogenome.org/gene/8478:NPY ^@ http://purl.uniprot.org/uniprot/A0A8C3IC89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NPY family.|||Secreted http://togogenome.org/gene/8478:CEBPA ^@ http://purl.uniprot.org/uniprot/A0A8C3F1M1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. C/EBP subfamily.|||Nucleus http://togogenome.org/gene/8478:FAM110C ^@ http://purl.uniprot.org/uniprot/A0A8C3IAK6 ^@ Similarity ^@ Belongs to the FAM110 family. http://togogenome.org/gene/8478:XDH ^@ http://purl.uniprot.org/uniprot/A0A8C3HCT8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the xanthine dehydrogenase family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Binds 2 [2Fe-2S] clusters.|||Peroxisome http://togogenome.org/gene/8478:RPS27L ^@ http://purl.uniprot.org/uniprot/A0A8C3HYK3 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eS27 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/8478:YAP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IVI1|||http://purl.uniprot.org/uniprot/A0A8C3IVP7|||http://purl.uniprot.org/uniprot/A0A8C3IYC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CFAP300 family.|||Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.|||Cytoplasm http://togogenome.org/gene/8478:LOC101952801 ^@ http://purl.uniprot.org/uniprot/A0A8C3I5F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|||Cytoplasm http://togogenome.org/gene/8478:CTLA4 ^@ http://purl.uniprot.org/uniprot/A0A8C3FP00 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.|||Membrane http://togogenome.org/gene/8478:DIPK1B ^@ http://purl.uniprot.org/uniprot/A0A8C3HDX7|||http://purl.uniprot.org/uniprot/A0A8C3HE53 ^@ Similarity ^@ Belongs to the DIPK family. http://togogenome.org/gene/8478:FAM221A ^@ http://purl.uniprot.org/uniprot/A0A8C3ICX7 ^@ Similarity ^@ Belongs to the FAM221 family. http://togogenome.org/gene/8478:DMAP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F8F5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:LOC101937200 ^@ http://purl.uniprot.org/uniprot/A0A8C3ILZ6 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/8478:CEP170 ^@ http://purl.uniprot.org/uniprot/A0A8C3FMZ2|||http://purl.uniprot.org/uniprot/A0A8C3FMZ8|||http://purl.uniprot.org/uniprot/A0A8C3FSY9|||http://purl.uniprot.org/uniprot/A0A8C3FVH4 ^@ Similarity ^@ Belongs to the CEP170 family. http://togogenome.org/gene/8478:LOC101942201 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Mitochondrion inner membrane|||Probably involved in the biogenesis of the COX complex. http://togogenome.org/gene/8478:SURF6 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8B6 ^@ Similarity ^@ Belongs to the SURF6 family. http://togogenome.org/gene/8478:SEPTIN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F423 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.|||Cleavage furrow|||Midbody|||cilium membrane|||spindle http://togogenome.org/gene/8478:RAB3GAP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FSV8|||http://purl.uniprot.org/uniprot/A0A8C3HB59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Rab3-GAP catalytic subunit family.|||Cytoplasm|||Endoplasmic reticulum http://togogenome.org/gene/8478:APOA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PAS9 ^@ Similarity ^@ Belongs to the apolipoprotein A1/A4/E family. http://togogenome.org/gene/8478:LOC101949854 ^@ http://purl.uniprot.org/uniprot/A0A8C3I1A6 ^@ Similarity ^@ Belongs to the G-alpha family. G(q) subfamily. http://togogenome.org/gene/8478:LOC101936919 ^@ http://purl.uniprot.org/uniprot/A0A8C3FTI0 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/8478:USP13 ^@ http://purl.uniprot.org/uniprot/A0A8C3ITV6|||http://purl.uniprot.org/uniprot/A0A8C3IUR7 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/8478:SLC39A9 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9E8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family.|||Cell membrane|||Membrane|||Mitochondrion|||Nucleus|||Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.|||perinuclear region|||trans-Golgi network membrane http://togogenome.org/gene/8478:HDHD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEL9 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/8478:SEC22B ^@ http://purl.uniprot.org/uniprot/A0A8C3H7G3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Melanosome|||Membrane|||SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.|||cis-Golgi network membrane|||trans-Golgi network membrane http://togogenome.org/gene/8478:HSPD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDB3 ^@ Similarity ^@ Belongs to the chaperonin (HSP60) family. http://togogenome.org/gene/8478:IL7 ^@ http://purl.uniprot.org/uniprot/A0A8C3FIP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IL-7/IL-9 family.|||Secreted http://togogenome.org/gene/8478:KATNB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IST6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat KATNB1 family.|||Cytoplasm|||Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome.|||Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.|||centrosome|||cytoskeleton|||spindle|||spindle pole http://togogenome.org/gene/8478:ARL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PD55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||centrosome http://togogenome.org/gene/8478:PAX3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family.|||Nucleus http://togogenome.org/gene/8478:C8H5orf24 ^@ http://purl.uniprot.org/uniprot/A0A8C3FQR4 ^@ Similarity ^@ Belongs to the UPF0461 family. http://togogenome.org/gene/8478:LOC101931395 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. http://togogenome.org/gene/8478:GPR50 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:TEK ^@ http://purl.uniprot.org/uniprot/A0A8C3FL05|||http://purl.uniprot.org/uniprot/A0A8C3H971|||http://purl.uniprot.org/uniprot/A0A8C3H9M0 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:PALS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICT2 ^@ Similarity ^@ Belongs to the MAGUK family. http://togogenome.org/gene/8478:COQ7 ^@ http://purl.uniprot.org/uniprot/A0A8C3FWP0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COQ7 family.|||Binds 2 iron ions per subunit.|||Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.|||Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:SLC16A4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F4B8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:LOC101935180 ^@ http://purl.uniprot.org/uniprot/A0A8C3FUT6|||http://purl.uniprot.org/uniprot/A0A8C3FW30 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:THG1L ^@ http://purl.uniprot.org/uniprot/A0A8C3F332 ^@ Cofactor|||Function|||Similarity ^@ Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.|||Belongs to the tRNA(His) guanylyltransferase family.|||Binds 2 magnesium ions per subunit. http://togogenome.org/gene/8478:FAM135A ^@ http://purl.uniprot.org/uniprot/A0A8C3II53|||http://purl.uniprot.org/uniprot/A0A8C3ILS7 ^@ Similarity ^@ Belongs to the FAM135 family. http://togogenome.org/gene/8478:SLC35A5 ^@ http://purl.uniprot.org/uniprot/A0A8C3F8L1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:PIK3CA ^@ http://purl.uniprot.org/uniprot/A0A8C3ITR8 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/8478:HOXA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICB0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:SHROOM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HT22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the shroom family.|||cytoskeleton http://togogenome.org/gene/8478:ADIPOR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/8478:LOC101936400 ^@ http://purl.uniprot.org/uniprot/A0A8C3I3F7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine beta (chemokine CC) family.|||Secreted http://togogenome.org/gene/8478:TJAP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQ47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:DNER ^@ http://purl.uniprot.org/uniprot/A0A8C3I457 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:SLC6A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F628 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/8478:GADD45A ^@ http://purl.uniprot.org/uniprot/A0A8C3F3T7 ^@ Similarity ^@ Belongs to the GADD45 family. http://togogenome.org/gene/8478:LOC101941478 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ClpA/ClpB family. Torsin subfamily.|||Endoplasmic reticulum lumen http://togogenome.org/gene/8478:TMCO4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMCO4 family.|||Membrane http://togogenome.org/gene/8478:UBE2B ^@ http://purl.uniprot.org/uniprot/A0A8C3FKP6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/8478:LOC101943564 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBE3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 6 family.|||Binds 1 Mn(2+) ion per subunit.|||Membrane http://togogenome.org/gene/8478:LOC101949927 ^@ http://purl.uniprot.org/uniprot/A0A8C3HD73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:TMEM132B ^@ http://purl.uniprot.org/uniprot/A0A8C3INT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM132 family.|||Membrane http://togogenome.org/gene/8478:CLP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Clp1 family. Clp1 subfamily.|||Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).|||Nucleus|||Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing. http://togogenome.org/gene/8478:TUT4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HN05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-B-like family.|||Cytoplasm http://togogenome.org/gene/8478:CD81 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7M1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/8478:PDE7A ^@ http://purl.uniprot.org/uniprot/A0A8C3I987 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/8478:ACTR3B ^@ http://purl.uniprot.org/uniprot/A0A8C3HYM7 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/8478:LOC101949949 ^@ http://purl.uniprot.org/uniprot/A0A8C3HML3|||http://purl.uniprot.org/uniprot/A0A8C3P6Z9 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).|||Nucleus http://togogenome.org/gene/8478:TRPC5 ^@ http://purl.uniprot.org/uniprot/A0A8C3HW10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:LOC101951164 ^@ http://purl.uniprot.org/uniprot/A0A8C3FHL2 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/8478:DNAI7 ^@ http://purl.uniprot.org/uniprot/A0A8C3FUD0 ^@ Similarity ^@ Belongs to the DNAI7 family. http://togogenome.org/gene/8478:TFB1M ^@ http://purl.uniprot.org/uniprot/A0A8C3P845 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/8478:SFT2D2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H762 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/8478:TTC38 ^@ http://purl.uniprot.org/uniprot/A0A8C3PDK3 ^@ Similarity ^@ Belongs to the TTC38 family. http://togogenome.org/gene/8478:CPVL ^@ http://purl.uniprot.org/uniprot/A0A8C3IGF9 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/8478:P2RX7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IT09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P2X receptor family.|||Membrane|||Receptor for ATP that acts as a ligand-gated ion channel. http://togogenome.org/gene/8478:KCNC4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F2I4|||http://purl.uniprot.org/uniprot/A0A8C3F2L7|||http://purl.uniprot.org/uniprot/A0A8C3F2U0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:LOC101941450 ^@ http://purl.uniprot.org/uniprot/A0A8C3IXB7|||http://purl.uniprot.org/uniprot/A0A8C3J1I4 ^@ Similarity ^@ Belongs to the aldo/keto reductase family. http://togogenome.org/gene/8478:C20H9orf78 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TLS1 family.|||Nucleus http://togogenome.org/gene/8478:LEPROT ^@ http://purl.uniprot.org/uniprot/A0A8C3F5V7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OB-RGRP/VPS55 family.|||Membrane http://togogenome.org/gene/8478:SDR42E1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHV8 ^@ Similarity ^@ Belongs to the 3-beta-HSD family. http://togogenome.org/gene/8478:CD99L2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7A0|||http://purl.uniprot.org/uniprot/A0A8C3I850 ^@ Similarity ^@ Belongs to the CD99 family. http://togogenome.org/gene/8478:TAGLN ^@ http://purl.uniprot.org/uniprot/A0A8C3I5W6 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/8478:NMD3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I0H0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.|||Belongs to the NMD3 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:NDUFB5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IWF5 ^@ Function|||Similarity|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB5 subunit family.|||Complex I is composed of 45 different subunits. http://togogenome.org/gene/8478:ENTPD3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGE8 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/8478:LOC101939806 ^@ http://purl.uniprot.org/uniprot/A0A8C3IVT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFC2 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:LOC101932518 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGP1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/8478:GKAP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IR77 ^@ Similarity ^@ Belongs to the GKAP1 family. http://togogenome.org/gene/8478:IMPA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3H9E1 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/8478:NID1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F9L8 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||basement membrane http://togogenome.org/gene/8478:ZNF830 ^@ http://purl.uniprot.org/uniprot/A0A8C3F141 ^@ Subcellular Location Annotation ^@ Chromosome|||Nucleus speckle http://togogenome.org/gene/8478:MMAB ^@ http://purl.uniprot.org/uniprot/A0A8C3IAG5 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/8478:SLC2A6 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBC9 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/8478:LTBP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPZ0|||http://purl.uniprot.org/uniprot/A0A8C3PE81 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/8478:GPR158 ^@ http://purl.uniprot.org/uniprot/A0A8C3HPX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 3 family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/8478:ATP23 ^@ http://purl.uniprot.org/uniprot/A0A8C3P6P2 ^@ Similarity ^@ Belongs to the peptidase M76 family. http://togogenome.org/gene/8478:MED27 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 27 family.|||Nucleus http://togogenome.org/gene/8478:LOC101944140 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2P3 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:LOC101934464 ^@ http://purl.uniprot.org/uniprot/A0A8C3HHI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRPH2/ROM1 family.|||Membrane http://togogenome.org/gene/8478:SGO1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IE38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the shugoshin family.|||centromere http://togogenome.org/gene/8478:DDX20 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9M1 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/8478:PLOD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCM6|||http://purl.uniprot.org/uniprot/A0A8C3P2L0 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/8478:ESR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P889 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nuclear hormone receptor family. NR3 subfamily.|||Binds DNA as a homodimer.|||Nucleus|||The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. http://togogenome.org/gene/8478:LAPTM4A ^@ http://purl.uniprot.org/uniprot/A0A8C3I4I8 ^@ Similarity ^@ Belongs to the LAPTM4/LAPTM5 transporter family. http://togogenome.org/gene/8478:GALNT15 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:USP22 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8C2|||http://purl.uniprot.org/uniprot/A0A8C3I9T1 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/8478:AIDA ^@ http://purl.uniprot.org/uniprot/A0A8C3HEN8 ^@ Similarity ^@ Belongs to the AIDA family. http://togogenome.org/gene/8478:WNT5A ^@ http://purl.uniprot.org/uniprot/A0A8C3I9A7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/8478:KAT2B ^@ http://purl.uniprot.org/uniprot/A0A8C3PCC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. GCN5 subfamily.|||Nucleus|||centrosome http://togogenome.org/gene/8478:BCHE ^@ http://purl.uniprot.org/uniprot/A0A8C3HS26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type-B carboxylesterase/lipase family.|||Secreted http://togogenome.org/gene/8478:SLC37A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FLW3|||http://purl.uniprot.org/uniprot/A0A8C3FQW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Membrane http://togogenome.org/gene/8478:SLC25A48 ^@ http://purl.uniprot.org/uniprot/A0A8C3FQX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/8478:TIMP4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQH9 ^@ Similarity ^@ Belongs to the protease inhibitor I35 (TIMP) family. http://togogenome.org/gene/8478:LOC101942818 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TOR1AIP family.|||Membrane http://togogenome.org/gene/8478:ARL6 ^@ http://purl.uniprot.org/uniprot/A0A8C3H7X4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||cilium membrane http://togogenome.org/gene/8478:TMOD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IXN3 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/8478:ZNRF3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IXK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZNRF3 family.|||Cell membrane http://togogenome.org/gene/8478:SYPL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptophysin/synaptobrevin family.|||Membrane http://togogenome.org/gene/8478:UPP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HT69 ^@ Function|||Similarity ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. http://togogenome.org/gene/8478:PARP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HD04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARTD/PARP family.|||Chromosome|||Nucleus|||Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. http://togogenome.org/gene/8478:TFPI2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJA9 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/8478:SCN3B ^@ http://purl.uniprot.org/uniprot/A0A8C3HNU6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.|||Membrane|||Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons. http://togogenome.org/gene/8478:WNT7B ^@ http://purl.uniprot.org/uniprot/A0A8C3PDI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/8478:CLCN6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IC44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel (TC 2.A.49) family.|||Membrane http://togogenome.org/gene/8478:IDNK ^@ http://purl.uniprot.org/uniprot/A0A8C3IPA3 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/8478:PRPSAP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8R2 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/8478:FICD ^@ http://purl.uniprot.org/uniprot/A0A8C3FGH0 ^@ Similarity ^@ Belongs to the fic family. http://togogenome.org/gene/8478:LOC101942869 ^@ http://purl.uniprot.org/uniprot/A0A8C3HHS3 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/8478:GRHL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HK22 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:DIPK2A ^@ http://purl.uniprot.org/uniprot/A0A8C3HCK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DIPK family.|||Secreted http://togogenome.org/gene/8478:PLCB4 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCW5 ^@ Cofactor|||Function ^@ Binds 1 Ca(2+) ion per subunit.|||The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. http://togogenome.org/gene/8478:TBX22 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLH7 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/8478:LOC103306138 ^@ http://purl.uniprot.org/uniprot/A0A8C3FLD0 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/8478:SLC9A3R2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F180 ^@ Function|||Subcellular Location Annotation ^@ Endomembrane system|||Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. http://togogenome.org/gene/8478:LMBR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYK2 ^@ Similarity ^@ Belongs to the LIMR family. http://togogenome.org/gene/8478:CBL ^@ http://purl.uniprot.org/uniprot/A0A8C3H9K6 ^@ Domain|||Function ^@ E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.|||The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain. http://togogenome.org/gene/8478:ST8SIA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FPE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/8478:LOC101946021 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RFamide neuropeptide family.|||Secreted http://togogenome.org/gene/8478:ZC3H12B ^@ http://purl.uniprot.org/uniprot/A0A8C3FIL6 ^@ Similarity ^@ Belongs to the ZC3H12 family. http://togogenome.org/gene/8478:MMD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PB43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/8478:DLGAP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FH76|||http://purl.uniprot.org/uniprot/A0A8C3FH92|||http://purl.uniprot.org/uniprot/A0A8C3FML8 ^@ Similarity ^@ Belongs to the SAPAP family. http://togogenome.org/gene/8478:SLU7 ^@ http://purl.uniprot.org/uniprot/A0A8C3H9P0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associated with the spliceosome.|||Belongs to the SLU7 family.|||Involved in pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/8478:TRPC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FP77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.|||Membrane|||Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. http://togogenome.org/gene/8478:NCOA7 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZM6|||http://purl.uniprot.org/uniprot/A0A8C3I175 ^@ Similarity ^@ Belongs to the OXR1 family. http://togogenome.org/gene/8478:DENND11 ^@ http://purl.uniprot.org/uniprot/A0A8C3P2C1 ^@ Similarity ^@ Belongs to the DENND11 family. http://togogenome.org/gene/8478:ORC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCC6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ORC2 family.|||Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.|||Component of the origin recognition complex (ORC).|||Nucleus http://togogenome.org/gene/8478:B9D1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8U7 ^@ Subcellular Location Annotation ^@ cilium basal body http://togogenome.org/gene/8478:LAMA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FH91 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||basement membrane http://togogenome.org/gene/8478:MLST8 ^@ http://purl.uniprot.org/uniprot/A0A8C3F246 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat LST8 family.|||Cytoplasm|||Part of TORC1 complex. Part of the TORC2 complex.|||Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. http://togogenome.org/gene/8478:ATP6V0C ^@ http://purl.uniprot.org/uniprot/A0A8C3IEE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.|||Vacuole membrane|||clathrin-coated vesicle membrane|||synaptic vesicle membrane http://togogenome.org/gene/8478:TM9SF3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FUE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.|||Membrane http://togogenome.org/gene/8478:OPRM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Endosome|||Membrane|||Perikaryon|||axon|||dendrite http://togogenome.org/gene/8478:BARX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3ITS8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:SLC35F2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC35F solute transporter family.|||Membrane http://togogenome.org/gene/8478:WNT2B ^@ http://purl.uniprot.org/uniprot/A0A8C3I9H5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/8478:DNASE1L3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKV0 ^@ Similarity ^@ Belongs to the DNase I family. http://togogenome.org/gene/8478:PSMD7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUN3 ^@ Similarity ^@ Belongs to the peptidase M67A family. http://togogenome.org/gene/8478:LOC101947136 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMO family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:RELT ^@ http://purl.uniprot.org/uniprot/A0A8C3FUA0 ^@ Similarity ^@ Belongs to the RELT family. http://togogenome.org/gene/8478:RPL18A ^@ http://purl.uniprot.org/uniprot/A0A8C3H5N4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL20 family. http://togogenome.org/gene/8478:NOP58 ^@ http://purl.uniprot.org/uniprot/A0A8C3HBV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP5/NOP56 family.|||nucleolus http://togogenome.org/gene/8478:CUEDC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PAX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUEDC2 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:COPB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2U0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat COPB2 family.|||COPI-coated vesicle membrane|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.|||This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner. http://togogenome.org/gene/8478:PARP6 ^@ http://purl.uniprot.org/uniprot/A0A8C3FIW1 ^@ Similarity ^@ Belongs to the ARTD/PARP family. http://togogenome.org/gene/8478:AGTR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUM3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Interacts with MTUS1.|||Membrane http://togogenome.org/gene/8478:CDPF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJ94 ^@ Similarity ^@ Belongs to the CDPF1 family. http://togogenome.org/gene/8478:BRS3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IRF6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Interacts with C6orf89.|||Membrane http://togogenome.org/gene/8478:BRI3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I4K0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRI3 family.|||Membrane|||perinuclear region http://togogenome.org/gene/8478:DRD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FMI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:NTMT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P518 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/8478:SIKE1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTT8 ^@ Similarity ^@ Belongs to the SIKE family. http://togogenome.org/gene/8478:LOC101949462 ^@ http://purl.uniprot.org/uniprot/A0A8C3HXN1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HARBI1 family.|||Cytoplasm|||Nucleus|||Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity. http://togogenome.org/gene/8478:IGBP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLT9 ^@ Similarity ^@ Belongs to the IGBP1/TAP42 family. http://togogenome.org/gene/8478:SIDT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I5B0|||http://purl.uniprot.org/uniprot/A0A8C3I5L4|||http://purl.uniprot.org/uniprot/A0A8C3I6G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SID1 family.|||Membrane http://togogenome.org/gene/8478:NECTIN3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FCE5 ^@ Similarity ^@ Belongs to the nectin family. http://togogenome.org/gene/8478:NKD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HR94|||http://purl.uniprot.org/uniprot/A0A8C3HRA1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NKD family.|||Cell autonomous antagonist of the canonical Wnt signaling pathway.|||Cell membrane|||Cytoplasm http://togogenome.org/gene/8478:ODF2L ^@ http://purl.uniprot.org/uniprot/A0A8C3IPT3|||http://purl.uniprot.org/uniprot/A0A8C3ISB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ODF2 family.|||centrosome http://togogenome.org/gene/8478:PLPP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HL51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/8478:MTMR9 ^@ http://purl.uniprot.org/uniprot/A0A8C3I771 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. http://togogenome.org/gene/8478:LOC101948426 ^@ http://purl.uniprot.org/uniprot/A0A8C3I4H9 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/8478:UBXN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HXH3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:HSP90AB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQ97 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/8478:LOC103305685 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKV4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/8478:PIK3CG ^@ http://purl.uniprot.org/uniprot/A0A8C3F0Q0 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/8478:LOC101945053 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVX7 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/8478:IRF2BP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H855 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IRF2BP family.|||Nucleus http://togogenome.org/gene/8478:PSMA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IL10 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/8478:SLC16A7 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.|||Membrane http://togogenome.org/gene/8478:RAB43 ^@ http://purl.uniprot.org/uniprot/A0A8C3IS89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Membrane http://togogenome.org/gene/8478:LOC101946611 ^@ http://purl.uniprot.org/uniprot/A0A8C3FHY0 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:CCDC93 ^@ http://purl.uniprot.org/uniprot/A0A8C3FTP5 ^@ Similarity ^@ Belongs to the CCDC93 family. http://togogenome.org/gene/8478:NXF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NXF family.|||Cytoplasm|||nucleoplasm http://togogenome.org/gene/8478:CUL4B ^@ http://purl.uniprot.org/uniprot/A0A8C3HG66 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/8478:ITPKB ^@ http://purl.uniprot.org/uniprot/A0A8C3HD17 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/8478:KCNT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P369 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/8478:LOC101947813 ^@ http://purl.uniprot.org/uniprot/A0A8C3F4Z5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:CHMP1B ^@ http://purl.uniprot.org/uniprot/A0A8C3HLJ6 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/8478:LOC101936107 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMP7 ^@ Similarity ^@ Belongs to the TTC38 family. http://togogenome.org/gene/8478:IGF2BP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FIF3|||http://purl.uniprot.org/uniprot/A0A8C3H997 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM IMP/VICKZ family.|||Cytoplasm http://togogenome.org/gene/8478:PTGS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FSF4 ^@ Caution|||Similarity ^@ Belongs to the prostaglandin G/H synthase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:TMEM120B ^@ http://purl.uniprot.org/uniprot/A0A8C3IQI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM120 family.|||Membrane|||Nucleus inner membrane http://togogenome.org/gene/8478:EDEM3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HS37|||http://purl.uniprot.org/uniprot/A0A8C3P7P4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 47 family. http://togogenome.org/gene/8478:SHCBP1L ^@ http://purl.uniprot.org/uniprot/A0A8C3HRH4 ^@ Subcellular Location Annotation ^@ spindle http://togogenome.org/gene/8478:BEND6 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICS6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:CNKSR3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTJ4 ^@ Similarity ^@ Belongs to the CNKSR family. http://togogenome.org/gene/8478:SUCNR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P9R1 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:SULF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FM27 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfatase family.|||Binds 1 Ca(2+) ion per subunit.|||Cell surface|||Endoplasmic reticulum|||Golgi stack|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/8478:DYNLT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEP6 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/8478:TMEM88B ^@ http://purl.uniprot.org/uniprot/A0A8C3IGU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM88 family.|||Membrane http://togogenome.org/gene/8478:MRPL19 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAX5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family. http://togogenome.org/gene/8478:ORC6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ORC6 family.|||Nucleus http://togogenome.org/gene/8478:GNAL ^@ http://purl.uniprot.org/uniprot/A0A8C3IZX9 ^@ Similarity ^@ Belongs to the G-alpha family. G(s) subfamily. http://togogenome.org/gene/8478:LTBP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJX1 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/8478:PARVB ^@ http://purl.uniprot.org/uniprot/A0A8C3IMW2|||http://purl.uniprot.org/uniprot/A0A8C3IQE8 ^@ Similarity ^@ Belongs to the parvin family. http://togogenome.org/gene/8478:MYO3A ^@ http://purl.uniprot.org/uniprot/A0A8C3HPE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.|||In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.|||cytoskeleton http://togogenome.org/gene/8478:SMAD5 ^@ http://purl.uniprot.org/uniprot/A0A8C3FMR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:LOC101932600 ^@ http://purl.uniprot.org/uniprot/A0A8C3I0T1 ^@ Similarity ^@ Belongs to the alpha-actinin family. http://togogenome.org/gene/8478:DMRTB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F7E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DMRT family.|||Nucleus http://togogenome.org/gene/8478:DLL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEU3 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Putative Notch ligand involved in the mediation of Notch signaling. http://togogenome.org/gene/8478:ABL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLH5|||http://purl.uniprot.org/uniprot/A0A8C3HLJ3|||http://purl.uniprot.org/uniprot/A0A8C3HM27 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/8478:TAF1B ^@ http://purl.uniprot.org/uniprot/A0A8C3HL36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRN7/TAF1B family.|||nucleolus http://togogenome.org/gene/8478:SLC9A9 ^@ http://purl.uniprot.org/uniprot/A0A8C3P2I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Endosome membrane|||Recycling endosome membrane http://togogenome.org/gene/8478:ARFGEF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HJX4 ^@ Subcellular Location Annotation ^@ Golgi apparatus|||perinuclear region http://togogenome.org/gene/8478:PDE3A ^@ http://purl.uniprot.org/uniprot/A0A8C3FPM1 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/8478:DAO ^@ http://purl.uniprot.org/uniprot/A0A8C3FM66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DAMOX/DASOX family.|||Peroxisome http://togogenome.org/gene/8478:ATP1A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F4R2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.|||Cell membrane http://togogenome.org/gene/8478:SCARB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3ILS0 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/8478:SHMT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IB37 ^@ Function|||Similarity ^@ Belongs to the SHMT family.|||Interconversion of serine and glycine. http://togogenome.org/gene/8478:HACD4 ^@ http://purl.uniprot.org/uniprot/A0A8C3I140|||http://purl.uniprot.org/uniprot/A0A8C3I148 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:ACSL3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I268 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/8478:TEKT4 ^@ http://purl.uniprot.org/uniprot/A0A8C3I812 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tektin family.|||flagellum http://togogenome.org/gene/8478:RFTN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICI1|||http://purl.uniprot.org/uniprot/A0A8C3IFI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the raftlin family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:XPR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3ITB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SYG1 (TC 2.A.94) family.|||Membrane http://togogenome.org/gene/8478:PRDM12 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class V-like SAM-binding methyltransferase superfamily.|||Involved in the positive regulation of histone H3-K9 dimethylation.|||Nucleus http://togogenome.org/gene/8478:LOC101948839 ^@ http://purl.uniprot.org/uniprot/A0A8C3IV23 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/8478:SEC61A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HL57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecY/SEC61-alpha family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:LOC101939800 ^@ http://purl.uniprot.org/uniprot/A0A8C3ID29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:CHMP4C ^@ http://purl.uniprot.org/uniprot/A0A8C3H9T6 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/8478:ITPKA ^@ http://purl.uniprot.org/uniprot/A0A8C3HIG3 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/8478:KMT5A ^@ http://purl.uniprot.org/uniprot/A0A8C3IU24 ^@ Subcellular Location Annotation ^@ Chromosome|||Nucleus http://togogenome.org/gene/8478:CDKN1B ^@ http://purl.uniprot.org/uniprot/A0A8C3EZY6 ^@ Similarity ^@ Belongs to the CDI family. http://togogenome.org/gene/8478:RRP36 ^@ http://purl.uniprot.org/uniprot/A0A8C3F907 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with 90S and pre-40S pre-ribosomal particles.|||Belongs to the RRP36 family.|||Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.|||nucleolus http://togogenome.org/gene/8478:ECHDC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZA4 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/8478:PML ^@ http://purl.uniprot.org/uniprot/A0A8C3HA38 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:LOC101941670 ^@ http://purl.uniprot.org/uniprot/A0A8C3HHH9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/8478:MOGAT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PA60 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:STAG2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P752 ^@ Similarity ^@ Belongs to the SCC3 family. http://togogenome.org/gene/8478:LOC101944509 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWH0 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/8478:LOC101935542 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9J9 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/8478:TMEM11 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7K8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM11 family.|||Membrane|||Plays a role in mitochondrial morphogenesis. http://togogenome.org/gene/8478:IRX4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRL0|||http://purl.uniprot.org/uniprot/A0A8C3HSA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/IRO homeobox family.|||Nucleus http://togogenome.org/gene/8478:ANO6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HP98 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anoctamin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:LOC101937031 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLC6 ^@ Similarity ^@ Belongs to the IAP family. http://togogenome.org/gene/8478:HMCES ^@ http://purl.uniprot.org/uniprot/A0A8C3HLK0 ^@ Function|||Similarity ^@ Belongs to the SOS response-associated peptidase family.|||Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction. http://togogenome.org/gene/8478:TRH ^@ http://purl.uniprot.org/uniprot/A0A8C3HM09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRH family.|||Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.|||Secreted http://togogenome.org/gene/8478:DCBLD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I0L5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:KLHL3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FNU0|||http://purl.uniprot.org/uniprot/A0A8C3FSQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KLHL3 family.|||cytoskeleton|||cytosol http://togogenome.org/gene/8478:RPL26L1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FK30 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL24 family. http://togogenome.org/gene/8478:NADK ^@ http://purl.uniprot.org/uniprot/A0A8C3IFA8 ^@ Similarity ^@ Belongs to the NAD kinase family. http://togogenome.org/gene/8478:SPTBN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IIA2 ^@ Similarity ^@ Belongs to the spectrin family. http://togogenome.org/gene/8478:MARK2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGE9|||http://purl.uniprot.org/uniprot/A0A8C3IJ18|||http://purl.uniprot.org/uniprot/A0A8C3PD07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.|||dendrite http://togogenome.org/gene/8478:SSU72 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEJ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SSU72 phosphatase family.|||Nucleus|||Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. http://togogenome.org/gene/8478:LOC101945284 ^@ http://purl.uniprot.org/uniprot/A0A8C3IB61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the natriuretic peptide family.|||Secreted http://togogenome.org/gene/8478:DESI2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FUV5 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/8478:FBXO45 ^@ http://purl.uniprot.org/uniprot/A0A8C3I933 ^@ Similarity ^@ Belongs to the FBXO45/Fsn family. http://togogenome.org/gene/8478:ST7 ^@ http://purl.uniprot.org/uniprot/A0A8C3FLJ3|||http://purl.uniprot.org/uniprot/A0A8C3FLK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ST7 family.|||Membrane http://togogenome.org/gene/8478:PACSIN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQ36|||http://purl.uniprot.org/uniprot/A0A8C3PE55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PACSIN family.|||Cell membrane|||Cytoplasmic vesicle membrane|||Early endosome|||Endosome membrane|||Membrane|||Recycling endosome membrane|||caveola|||cytoskeleton|||ruffle membrane http://togogenome.org/gene/8478:IGFLR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3H5W4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:CCND3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWG2 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/8478:ACAA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZI7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/8478:ATG4A ^@ http://purl.uniprot.org/uniprot/A0A8C3F038 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C54 family.|||Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.|||Cytoplasm http://togogenome.org/gene/8478:SYNDIG1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FZ35 ^@ Similarity ^@ Belongs to the CD225/Dispanin family. http://togogenome.org/gene/8478:FOXJ2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HAI8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:EXOC8 ^@ http://purl.uniprot.org/uniprot/A0A8C3FF21 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EXO84 family.|||Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.|||growth cone|||perinuclear region http://togogenome.org/gene/8478:SGK1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HXC3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:CNPY1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYR2 ^@ Similarity ^@ Belongs to the canopy family. http://togogenome.org/gene/8478:RAB32 ^@ http://purl.uniprot.org/uniprot/A0A8C3P8C6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Membrane|||The small GTPases Rab are key regulators in vesicle trafficking. http://togogenome.org/gene/8478:DYNC1LI1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDT6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.|||Belongs to the dynein light intermediate chain family.|||Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).|||cytoskeleton http://togogenome.org/gene/8478:WSCD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJY9 ^@ Function|||Similarity ^@ Belongs to the WSCD family.|||Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans. http://togogenome.org/gene/8478:CEMIP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I6Y9 ^@ Similarity ^@ Belongs to the CEMIP family. http://togogenome.org/gene/8478:LOC101943877 ^@ http://purl.uniprot.org/uniprot/A0A8C3PA20 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:NUSAP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HI33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NUSAP family.|||Cytoplasm http://togogenome.org/gene/8478:LOC101944657 ^@ http://purl.uniprot.org/uniprot/A0A8C3FL26 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/8478:TTYH3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I6Y3|||http://purl.uniprot.org/uniprot/A0A8C3I708|||http://purl.uniprot.org/uniprot/A0A8C3IA21 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tweety family.|||Cell membrane|||Membrane|||Probable chloride channel. http://togogenome.org/gene/8478:ILDR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FEN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the immunoglobulin superfamily. LISCH7 family.|||Membrane|||tight junction http://togogenome.org/gene/8478:RPL22L1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRF8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/8478:EOGT ^@ http://purl.uniprot.org/uniprot/A0A8C3H585 ^@ Similarity ^@ Belongs to the glycosyltransferase 61 family. http://togogenome.org/gene/8478:CRHR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family.|||Membrane http://togogenome.org/gene/8478:CSNK1A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FKN6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:LOC101953972 ^@ http://purl.uniprot.org/uniprot/A0A8C3FAJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:FUBP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDH6|||http://purl.uniprot.org/uniprot/A0A8C3IFU7|||http://purl.uniprot.org/uniprot/A0A8C3IFV7|||http://purl.uniprot.org/uniprot/A0A8C3PCE2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:MFSD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZ18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:COQ10B ^@ http://purl.uniprot.org/uniprot/A0A8C3IEC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the COQ10 family.|||Interacts with coenzyme Q.|||Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes. http://togogenome.org/gene/8478:CMTM8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDS5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:MED21 ^@ http://purl.uniprot.org/uniprot/A0A8C3IIJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 21 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/8478:GBF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I5V4 ^@ Subcellular Location Annotation ^@ Golgi apparatus http://togogenome.org/gene/8478:MBTPS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDC2 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/8478:LOC101951876 ^@ http://purl.uniprot.org/uniprot/A0A8C3H6H0 ^@ Similarity ^@ Belongs to the HEBP family. http://togogenome.org/gene/8478:MET ^@ http://purl.uniprot.org/uniprot/A0A8C3H8R4 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:SUSD3 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICQ3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:BRMS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFS2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:MTRFR ^@ http://purl.uniprot.org/uniprot/A0A8C3IQM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Mitochondrion http://togogenome.org/gene/8478:STEAP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3ID20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:SLC39A6 ^@ http://purl.uniprot.org/uniprot/A0A8C3F562 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:DCAF10 ^@ http://purl.uniprot.org/uniprot/A0A8C3FHA1 ^@ Function|||Similarity ^@ Belongs to the WD repeat DCAF10 family.|||May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. http://togogenome.org/gene/8478:SAP30L ^@ http://purl.uniprot.org/uniprot/A0A8C3F3U3 ^@ Similarity ^@ Belongs to the SAP30 family. http://togogenome.org/gene/8478:BRINP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FFH1 ^@ Similarity ^@ Belongs to the BRINP family. http://togogenome.org/gene/8478:ZC3H12A ^@ http://purl.uniprot.org/uniprot/A0A8C3P9K4 ^@ Similarity ^@ Belongs to the ZC3H12 family. http://togogenome.org/gene/8478:LOC101946049 ^@ http://purl.uniprot.org/uniprot/A0A8C3P8X8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM47 family.|||Membrane http://togogenome.org/gene/8478:TBK1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F7X4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:CENPO ^@ http://purl.uniprot.org/uniprot/A0A8C3PC50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CENP-O/MCM21 family.|||Nucleus http://togogenome.org/gene/8478:PUS7L ^@ http://purl.uniprot.org/uniprot/A0A8C3HQW9 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruD family. http://togogenome.org/gene/8478:IMMP1L ^@ http://purl.uniprot.org/uniprot/A0A8C3HCE3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S26 family.|||Heterodimer of 2 subunits, IMMPL1 and IMMPL2.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:EXO1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FMR2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.|||Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Nucleus http://togogenome.org/gene/8478:OVOL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFE3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:MRPS15 ^@ http://purl.uniprot.org/uniprot/A0A8C3I163 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/8478:CUL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P8C2 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/8478:LOC101936674 ^@ http://purl.uniprot.org/uniprot/A0A8C3F8D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus http://togogenome.org/gene/8478:SLC25A5 ^@ http://purl.uniprot.org/uniprot/A0A8C3I6I7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/8478:TFCP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P9A9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the grh/CP2 family. CP2 subfamily.|||Nucleus http://togogenome.org/gene/8478:GLB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F340 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/8478:WASHC3 ^@ http://purl.uniprot.org/uniprot/A0A8C3F8C8 ^@ Similarity ^@ Belongs to the CCDC53 family. http://togogenome.org/gene/8478:PSEN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCX7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase A22A family.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Homodimer.|||Membrane|||Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.|||The PAL motif is required for normal active site conformation. http://togogenome.org/gene/8478:SPI1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IE84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/8478:PPTC7 ^@ http://purl.uniprot.org/uniprot/A0A8C3F6W7 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/8478:MTMR8 ^@ http://purl.uniprot.org/uniprot/A0A8C3FBV7 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. http://togogenome.org/gene/8478:GLRA3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IK46 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Postsynaptic cell membrane|||Synapse|||Synaptic cell membrane http://togogenome.org/gene/8478:SLC2A13 ^@ http://purl.uniprot.org/uniprot/A0A8C3FUX1 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/8478:LOC101942537 ^@ http://purl.uniprot.org/uniprot/A0A8C3IS49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TOR1AIP family.|||Membrane http://togogenome.org/gene/8478:GNG10 ^@ http://purl.uniprot.org/uniprot/A0A8C3FRG1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/8478:SH3BGRL ^@ http://purl.uniprot.org/uniprot/A0A8C3HLG1 ^@ Similarity ^@ Belongs to the SH3BGR family. http://togogenome.org/gene/8478:LOC101938302 ^@ http://purl.uniprot.org/uniprot/A0A8C3FQM5 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/8478:LOC101950060 ^@ http://purl.uniprot.org/uniprot/A0A8C3FF27|||http://purl.uniprot.org/uniprot/A0A8C3FKN2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/8478:LARS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FMS0 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/8478:LOC101942922 ^@ http://purl.uniprot.org/uniprot/A0A8C3FXL3 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase class-1 family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/8478:CAPZB ^@ http://purl.uniprot.org/uniprot/A0A8C3IGV5|||http://purl.uniprot.org/uniprot/A0A8C3IHK3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the F-actin-capping protein beta subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit.|||cytoskeleton http://togogenome.org/gene/8478:PBX3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IZE3|||http://purl.uniprot.org/uniprot/A0A8C3J109 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/PBX homeobox family.|||Nucleus http://togogenome.org/gene/8478:RSBN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P7I3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the round spermatid basic protein 1 family.|||Nucleus http://togogenome.org/gene/8478:SERINC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P9N5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TDE1 family.|||Membrane http://togogenome.org/gene/8478:AK4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F2T2|||http://purl.uniprot.org/uniprot/A0A8C3F3Z6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Belongs to the adenylate kinase family. AK3 subfamily.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.|||Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.|||Mitochondrion matrix|||Monomer. http://togogenome.org/gene/8478:SH2B3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FC83 ^@ Similarity ^@ Belongs to the SH2B adapter family. http://togogenome.org/gene/8478:LOC101945074 ^@ http://purl.uniprot.org/uniprot/A0A8C3IZL6 ^@ Similarity ^@ Belongs to the aldo/keto reductase family. http://togogenome.org/gene/8478:LOC101935267 ^@ http://purl.uniprot.org/uniprot/A0A8C3F709 ^@ Similarity ^@ Belongs to the multicopper oxidase family. http://togogenome.org/gene/8478:STK38L ^@ http://purl.uniprot.org/uniprot/A0A8C3IFV3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:NOTCH1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HE14 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOTCH family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Nucleus http://togogenome.org/gene/8478:GPR137B ^@ http://purl.uniprot.org/uniprot/A0A8C3FCV3 ^@ Subcellular Location Annotation ^@ Lysosome membrane|||Membrane http://togogenome.org/gene/8478:TPRA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0359 family.|||Membrane http://togogenome.org/gene/8478:SYNPR ^@ http://purl.uniprot.org/uniprot/A0A8C3ITS3|||http://purl.uniprot.org/uniprot/A0A8C3IU75|||http://purl.uniprot.org/uniprot/A0A8C3PFG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptophysin/synaptobrevin family.|||Membrane http://togogenome.org/gene/8478:DBX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HPU9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:LOC101932458 ^@ http://purl.uniprot.org/uniprot/A0A8C3FLN7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:TARS3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FV87 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/8478:ZRANB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCB0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZRANB2 family.|||May interfere with constitutive 5'-splice site selection.|||Nucleus http://togogenome.org/gene/8478:GPR89B ^@ http://purl.uniprot.org/uniprot/A0A8C3FEV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Golgi pH regulator (TC 1.A.38) family.|||Membrane http://togogenome.org/gene/8478:TRAPPC3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZT6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum|||Homodimer.|||May play a role in vesicular transport from endoplasmic reticulum to Golgi.|||cis-Golgi network http://togogenome.org/gene/8478:TBX19 ^@ http://purl.uniprot.org/uniprot/A0A8C3F9Q1 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/8478:LOC101945756 ^@ http://purl.uniprot.org/uniprot/A0A8C3I5F7 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/8478:LOC101937225 ^@ http://purl.uniprot.org/uniprot/A0A8C3HER5 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/8478:ALX4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HF54 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:SLC9A5 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Membrane|||Recycling endosome membrane http://togogenome.org/gene/8478:FGFR1OP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHF4 ^@ Similarity ^@ Belongs to the SIKE family. http://togogenome.org/gene/8478:CLNS1A ^@ http://purl.uniprot.org/uniprot/A0A8C3IXY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the pICln (TC 1.A.47) family.|||Nucleus http://togogenome.org/gene/8478:ALKBH5 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8S6 ^@ Subcellular Location Annotation|||Subunit ^@ Monomer.|||Nucleus speckle http://togogenome.org/gene/8478:NTS ^@ http://purl.uniprot.org/uniprot/A0A8C3EYL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the neurotensin family.|||Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.|||Secreted|||Vesicle|||secretory vesicle http://togogenome.org/gene/8478:AGPAT5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBI8 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/8478:LOC101952198 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVX0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RRM NCBP2 family.|||Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.|||Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.|||Nucleus http://togogenome.org/gene/8478:HOXA6 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/8478:TOP3A ^@ http://purl.uniprot.org/uniprot/A0A8C3I7G7 ^@ Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. http://togogenome.org/gene/8478:TXNRD3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLA8 ^@ Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/8478:SLC25A27 ^@ http://purl.uniprot.org/uniprot/A0A8C3IA89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/8478:TMEM200C ^@ http://purl.uniprot.org/uniprot/A0A8C3FGU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM200 family.|||Membrane http://togogenome.org/gene/8478:PRICKLE1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HQH0 ^@ Similarity ^@ Belongs to the prickle / espinas / testin family. http://togogenome.org/gene/8478:CUL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUU2 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/8478:XPC ^@ http://purl.uniprot.org/uniprot/A0A8C3HLL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XPC family.|||Nucleus http://togogenome.org/gene/8478:EPHA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FTU7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:NDUFA5 ^@ http://purl.uniprot.org/uniprot/A0A8C3I6E0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA5 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:CEP19 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9A8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CEP19 family.|||centriole|||cilium basal body|||spindle pole http://togogenome.org/gene/8478:NDUFA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I916 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA1 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:PSMC3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEA5 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/8478:EPHA3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FKD4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:RPS16 ^@ http://purl.uniprot.org/uniprot/A0A8C3H555 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/8478:IFT57 ^@ http://purl.uniprot.org/uniprot/A0A8C3H7P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IFT57 family.|||cilium basal body http://togogenome.org/gene/8478:LOC101945004 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the natriuretic peptide family.|||Secreted http://togogenome.org/gene/8478:SCAMP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IA99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SCAMP family.|||Membrane http://togogenome.org/gene/8478:KCNJ8 ^@ http://purl.uniprot.org/uniprot/A0A8C3FPI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/8478:TMEM245 ^@ http://purl.uniprot.org/uniprot/A0A8C3F5V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/8478:SENP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FM32|||http://purl.uniprot.org/uniprot/A0A8C3H8V7 ^@ Similarity ^@ Belongs to the peptidase C48 family. http://togogenome.org/gene/8478:TMEM237 ^@ http://purl.uniprot.org/uniprot/A0A8C3HC78 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM237 family.|||Component of the transition zone in primary cilia. Required for ciliogenesis.|||Membrane|||cilium http://togogenome.org/gene/8478:SLC1A2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HET7|||http://purl.uniprot.org/uniprot/A0A8C3HEU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/8478:FAM163B ^@ http://purl.uniprot.org/uniprot/A0A8C3IBF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM163 family.|||Membrane http://togogenome.org/gene/8478:XPO5 ^@ http://purl.uniprot.org/uniprot/A0A8C3INB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Cytoplasm http://togogenome.org/gene/8478:TSC22D2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMG1 ^@ Similarity ^@ Belongs to the TSC-22/Dip/Bun family. http://togogenome.org/gene/8478:ABCB9 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEU8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:PRKCZ ^@ http://purl.uniprot.org/uniprot/A0A8C3IEQ6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. http://togogenome.org/gene/8478:TSPAN9 ^@ http://purl.uniprot.org/uniprot/A0A8C3FS37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/8478:THEMIS ^@ http://purl.uniprot.org/uniprot/A0A8C3P9J1 ^@ Similarity ^@ Belongs to the themis family. http://togogenome.org/gene/8478:ATP6V1E1 ^@ http://purl.uniprot.org/uniprot/A0A8C3J158 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/8478:PIK3C2B ^@ http://purl.uniprot.org/uniprot/A0A8C3F1K4 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/8478:KBTBD8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KBTBD8 family.|||Golgi apparatus|||spindle http://togogenome.org/gene/8478:SULT6B1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PD52 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/8478:ATG2A ^@ http://purl.uniprot.org/uniprot/A0A8C3IHA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG2 family.|||Endoplasmic reticulum membrane|||Lipid droplet|||Preautophagosomal structure membrane http://togogenome.org/gene/8478:NCK2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FIE9 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Endoplasmic reticulum http://togogenome.org/gene/8478:YIPF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F6J5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Endosome membrane|||Golgi apparatus membrane|||Late endosome membrane|||Membrane|||cis-Golgi network membrane|||trans-Golgi network membrane http://togogenome.org/gene/8478:AK1 ^@ http://purl.uniprot.org/uniprot/A0A8C3ILK8|||http://purl.uniprot.org/uniprot/A0A8C3IMU8|||http://purl.uniprot.org/uniprot/A0A8C3IPZ4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK1 subfamily.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Monomer. http://togogenome.org/gene/8478:TMEM35B ^@ http://purl.uniprot.org/uniprot/A0A8C3I1N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/8478:LOC101934764 ^@ http://purl.uniprot.org/uniprot/A0A8C3HD22 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/8478:ST3GAL6 ^@ http://purl.uniprot.org/uniprot/A0A8C3F839 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/8478:DRC7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DRC7 family.|||cilium axoneme|||flagellum|||flagellum axoneme http://togogenome.org/gene/8478:ABI1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HQX4|||http://purl.uniprot.org/uniprot/A0A8C3HR01|||http://purl.uniprot.org/uniprot/A0A8C3HRJ8|||http://purl.uniprot.org/uniprot/A0A8C3HRU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABI family.|||cytoskeleton|||filopodium|||lamellipodium http://togogenome.org/gene/8478:LOC101946482 ^@ http://purl.uniprot.org/uniprot/A0A8C3PD30 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase IV family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/8478:MYCN ^@ http://purl.uniprot.org/uniprot/A0A8C3P5K7 ^@ Subcellular Location Annotation|||Subunit ^@ Efficient DNA binding requires dimerization with another bHLH protein.|||Nucleus http://togogenome.org/gene/8478:ENTPD6 ^@ http://purl.uniprot.org/uniprot/A0A8C3FWK8 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/8478:PRIM2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IG16 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the eukaryotic-type primase large subunit family.|||Binds 1 [4Fe-4S] cluster.|||Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. http://togogenome.org/gene/8478:ACTR8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IA51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the actin family. ARP8 subfamily.|||Chromosome|||Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.|||Nucleus|||Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.|||Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. http://togogenome.org/gene/8478:FLNB ^@ http://purl.uniprot.org/uniprot/A0A8C3HKR3|||http://purl.uniprot.org/uniprot/A0A8C3HKU4|||http://purl.uniprot.org/uniprot/A0A8C3HLB1 ^@ Similarity ^@ Belongs to the filamin family. http://togogenome.org/gene/8478:TRIM45 ^@ http://purl.uniprot.org/uniprot/A0A8C3F7Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRIM/RBCC family.|||Cytoplasm http://togogenome.org/gene/8478:MEAF6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZG1|||http://purl.uniprot.org/uniprot/A0A8C3HZG5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EAF6 family.|||Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.|||Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.|||kinetochore|||nucleolus http://togogenome.org/gene/8478:GPRC5B ^@ http://purl.uniprot.org/uniprot/A0A8C3P9B2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/8478:SKA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPQ6 ^@ Similarity ^@ Belongs to the SKA1 family. http://togogenome.org/gene/8478:LOC101937461 ^@ http://purl.uniprot.org/uniprot/A0A8C3FR57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:TGFBR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3ID04|||http://purl.uniprot.org/uniprot/A0A8C3PCF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Cell membrane|||Membrane|||Membrane raft|||Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways. http://togogenome.org/gene/8478:METTL16 ^@ http://purl.uniprot.org/uniprot/A0A8C3F3B3 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. METTL16/RlmF family.|||RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. http://togogenome.org/gene/8478:LOC101954021 ^@ http://purl.uniprot.org/uniprot/A0A8C3P888 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UQCRQ/QCR8 family.|||Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/8478:VPS35 ^@ http://purl.uniprot.org/uniprot/A0A8C3HSG3 ^@ Function|||Similarity ^@ Belongs to the VPS35 family.|||Plays a role in vesicular protein sorting. http://togogenome.org/gene/8478:ALX3 ^@ http://purl.uniprot.org/uniprot/A0A8C3F2N8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:P2RY2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HBB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:LCLAT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCN5 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/8478:KCNA6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IIZ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:MIGA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDZ9 ^@ Similarity ^@ Belongs to the mitoguardin family. http://togogenome.org/gene/8478:TMEM163 ^@ http://purl.uniprot.org/uniprot/A0A8C3FTA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM163 family.|||Membrane|||synaptic vesicle membrane http://togogenome.org/gene/8478:GPR17 ^@ http://purl.uniprot.org/uniprot/A0A8C3I272 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:NUP93 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCZ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleoporin interacting component (NIC) family.|||Nucleus membrane|||Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.|||nuclear pore complex http://togogenome.org/gene/8478:TERT ^@ http://purl.uniprot.org/uniprot/A0A8C3P7X4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the reverse transcriptase family. Telomerase subfamily.|||Nucleus|||Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.|||telomere http://togogenome.org/gene/8478:DCLRE1B ^@ http://purl.uniprot.org/uniprot/A0A8C3HQB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.|||Nucleus http://togogenome.org/gene/8478:IRAK4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HQ61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.|||Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.|||Cytoplasm|||Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. http://togogenome.org/gene/8478:LOC101942967 ^@ http://purl.uniprot.org/uniprot/A0A8C3P4W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMO family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:TNR ^@ http://purl.uniprot.org/uniprot/A0A8C3HLX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tenascin family.|||extracellular matrix http://togogenome.org/gene/8478:GNG12 ^@ http://purl.uniprot.org/uniprot/A0A8C3F6V2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/8478:BCAS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HSW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPF27 family.|||Nucleus http://togogenome.org/gene/8478:KCTD3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HGR1 ^@ Similarity ^@ Belongs to the KCTD3 family. http://togogenome.org/gene/8478:ADGRF5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.|||Membrane http://togogenome.org/gene/8478:LOC101943333 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBU7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:HBP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F7N2 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. http://togogenome.org/gene/8478:TAF5L ^@ http://purl.uniprot.org/uniprot/A0A8C3FEU8 ^@ Similarity ^@ Belongs to the WD repeat TAF5 family. http://togogenome.org/gene/8478:CACHD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F3J5 ^@ Similarity ^@ Belongs to the calcium channel subunit alpha-2/delta family. http://togogenome.org/gene/8478:SKP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FK29 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. http://togogenome.org/gene/8478:STEEP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PB27 ^@ Similarity ^@ Belongs to the STEEP1 family. http://togogenome.org/gene/8478:ARPC3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQS3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ARPC3 family.|||Component of the Arp2/3 complex.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.|||cytoskeleton http://togogenome.org/gene/8478:SLC16A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I243 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.|||Membrane http://togogenome.org/gene/8478:EXT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 47 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/8478:FGF16 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMT9 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/8478:ANKRD13A ^@ http://purl.uniprot.org/uniprot/A0A8C3I9X5|||http://purl.uniprot.org/uniprot/A0A8C3IC91 ^@ Function|||Subcellular Location Annotation ^@ Endosome|||Late endosome|||Membrane|||Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. http://togogenome.org/gene/8478:SLC2A5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBS3 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/8478:LOC101937351 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFM2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the p22phox family.|||Cell membrane|||Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).|||Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.|||Membrane http://togogenome.org/gene/8478:MTM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I775 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.|||Cytoplasm http://togogenome.org/gene/8478:GLUL ^@ http://purl.uniprot.org/uniprot/A0A8C3HQV6 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/8478:CACNB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HNF9|||http://purl.uniprot.org/uniprot/A0A8C3HP03 ^@ Similarity ^@ Belongs to the calcium channel beta subunit family. http://togogenome.org/gene/8478:KCNK5 ^@ http://purl.uniprot.org/uniprot/A0A8C3INZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/8478:LOC101942193 ^@ http://purl.uniprot.org/uniprot/A0A8C3FU46 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SOSS-C family.|||Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).|||Component of the SOSS complex.|||Nucleus http://togogenome.org/gene/8478:UCK2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMC3 ^@ Similarity ^@ Belongs to the uridine kinase family. http://togogenome.org/gene/8478:TBL3 ^@ http://purl.uniprot.org/uniprot/A0A8C3EY85 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/8478:MTCH2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/8478:AHCYL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F322 ^@ Similarity ^@ Belongs to the adenosylhomocysteinase family. http://togogenome.org/gene/8478:PGD ^@ http://purl.uniprot.org/uniprot/A0A8C3IBK7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/8478:MEMO1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJ97 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/8478:DNAAF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HD83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNAAF1 family.|||Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli.|||cilium http://togogenome.org/gene/8478:EXOC3 ^@ http://purl.uniprot.org/uniprot/A0A8C3H5L7 ^@ Similarity ^@ Belongs to the SEC6 family. http://togogenome.org/gene/8478:DRAXIN ^@ http://purl.uniprot.org/uniprot/A0A8C3IEK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the draxin family.|||Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord.|||Secreted http://togogenome.org/gene/8478:HRH1 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:LOC101935791 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Nucleus http://togogenome.org/gene/8478:LOC101933992 ^@ http://purl.uniprot.org/uniprot/A0A8C3IE92 ^@ Similarity ^@ Belongs to the TMEM178 family. http://togogenome.org/gene/8478:NACC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDH0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:TWSG1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IZJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the twisted gastrulation protein family.|||Secreted http://togogenome.org/gene/8478:THOC7 ^@ http://purl.uniprot.org/uniprot/A0A8C3ITD2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the THOC7 family.|||Nucleus|||Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. http://togogenome.org/gene/8478:VLDLR ^@ http://purl.uniprot.org/uniprot/A0A8C3IME8|||http://purl.uniprot.org/uniprot/A0A8C3PEC4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:CAMKK2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IT54 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:ARMC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9B7 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/8478:NPL ^@ http://purl.uniprot.org/uniprot/A0A8C3HRI3 ^@ Similarity|||Subunit ^@ Belongs to the DapA family.|||Homotetramer. http://togogenome.org/gene/8478:SLC29A2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGM3 ^@ Similarity|||Subcellular Location Annotation ^@ Basolateral cell membrane|||Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Lateral cell membrane|||Membrane http://togogenome.org/gene/8478:ACBD5 ^@ http://purl.uniprot.org/uniprot/A0A8C3P7T3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.|||Belongs to the ATG37 family.|||Membrane http://togogenome.org/gene/8478:PDCD10 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDCD10 family.|||Cell membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:LOC101937707 ^@ http://purl.uniprot.org/uniprot/A0A8C3HSS4 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Membrane|||Mitochondrion inner membrane|||The Rieske protein is a high potential 2Fe-2S protein. http://togogenome.org/gene/8478:B4GALNT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P977 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:RAB39A ^@ http://purl.uniprot.org/uniprot/A0A8C3HZS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:HUS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVB0 ^@ Similarity ^@ Belongs to the HUS1 family. http://togogenome.org/gene/8478:ADA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3J2Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.|||Secreted http://togogenome.org/gene/8478:CCR4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F0J3 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:LOC101951042 ^@ http://purl.uniprot.org/uniprot/A0A8C3IA02 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:DNAJC16 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJI4 ^@ Function|||Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Plays an important role in regulating the size of autophagosomes during the formation process. http://togogenome.org/gene/8478:TENT5C ^@ http://purl.uniprot.org/uniprot/A0A8C3F252 ^@ Similarity ^@ Belongs to the TENT family. http://togogenome.org/gene/8478:PLD5 ^@ http://purl.uniprot.org/uniprot/A0A8C3FNX2|||http://purl.uniprot.org/uniprot/A0A8C3HA54 ^@ Similarity ^@ Belongs to the phospholipase D family. http://togogenome.org/gene/8478:POLR1B ^@ http://purl.uniprot.org/uniprot/A0A8C3F8N5|||http://purl.uniprot.org/uniprot/A0A8C3FHI6 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft. http://togogenome.org/gene/8478:LOC101949838 ^@ http://purl.uniprot.org/uniprot/A0A8C3F080 ^@ Similarity ^@ Belongs to the cystatin family. http://togogenome.org/gene/8478:SEC61B ^@ http://purl.uniprot.org/uniprot/A0A8C3EZX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC61-beta family.|||Endoplasmic reticulum membrane|||Membrane|||Necessary for protein translocation in the endoplasmic reticulum. http://togogenome.org/gene/8478:EEF1G ^@ http://purl.uniprot.org/uniprot/A0A8C3HYB6 ^@ Function|||Subunit ^@ EF-1 is composed of four subunits: alpha, beta, delta, and gamma.|||Probably plays a role in anchoring the complex to other cellular components. http://togogenome.org/gene/8478:SIDT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F2Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SID1 family.|||Membrane http://togogenome.org/gene/8478:NEK6 ^@ http://purl.uniprot.org/uniprot/A0A8C3PGB8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:LOC101932352 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDE2 ^@ Similarity|||Subunit ^@ Belongs to the CutA family.|||Homotrimer. http://togogenome.org/gene/8478:FUT11 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7J4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane|||Probable fucosyltransferase. http://togogenome.org/gene/8478:DUSP10 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZB9 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. http://togogenome.org/gene/8478:XRN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFT5 ^@ Function|||Similarity ^@ Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.|||Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. http://togogenome.org/gene/8478:OGT ^@ http://purl.uniprot.org/uniprot/A0A8C3HU85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.|||Cell projection|||Mitochondrion membrane http://togogenome.org/gene/8478:LOC101946875 ^@ http://purl.uniprot.org/uniprot/A0A8C3FQE5 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:PPM1L ^@ http://purl.uniprot.org/uniprot/A0A8C3I0G3 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/8478:SMPDL3A ^@ http://purl.uniprot.org/uniprot/A0A8C3I0N0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acid sphingomyelinase family.|||Binds 2 Zn(2+) per subunit.|||Secreted http://togogenome.org/gene/8478:RPL15 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL15 family.|||Cytoplasm http://togogenome.org/gene/8478:CZIB ^@ http://purl.uniprot.org/uniprot/A0A8C3F6E6 ^@ Similarity ^@ Belongs to the UPF0587 family. http://togogenome.org/gene/8478:ZDHHC5 ^@ http://purl.uniprot.org/uniprot/A0A8C3HV31 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/8478:LRP8 ^@ http://purl.uniprot.org/uniprot/A0A8C3F6H6|||http://purl.uniprot.org/uniprot/A0A8C3F6R1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:LOC101935518 ^@ http://purl.uniprot.org/uniprot/A0A8C3HL40 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/8478:RBM15 ^@ http://purl.uniprot.org/uniprot/A0A8C3F498 ^@ Similarity ^@ Belongs to the RRM Spen family. http://togogenome.org/gene/8478:GCNT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I3P5 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:CAMK2A ^@ http://purl.uniprot.org/uniprot/A0A8C3FT75|||http://purl.uniprot.org/uniprot/A0A8C3FZ26 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. http://togogenome.org/gene/8478:YTHDF3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9B2 ^@ Function|||Similarity ^@ Belongs to the YTHDF family.|||Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing. http://togogenome.org/gene/8478:PTPRK ^@ http://purl.uniprot.org/uniprot/A0A8C3I030 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.|||Membrane http://togogenome.org/gene/8478:LOC101936303 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZ95 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the hcp beta-lactamase family.|||Mitochondrion intermembrane space|||Required for assembly of mitochondrial respiratory chain complexes. http://togogenome.org/gene/8478:CCDC181 ^@ http://purl.uniprot.org/uniprot/A0A8C3F7T2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CCDC181 family.|||Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.|||cytoskeleton http://togogenome.org/gene/8478:TMEM218 ^@ http://purl.uniprot.org/uniprot/A0A8C3FXE8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM218 family.|||May be involved in ciliary biogenesis or function.|||Membrane|||cilium http://togogenome.org/gene/8478:DPH3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFH0 ^@ Similarity ^@ Belongs to the DPH3 family. http://togogenome.org/gene/8478:CAPRIN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3ITT0|||http://purl.uniprot.org/uniprot/A0A8C3IV42|||http://purl.uniprot.org/uniprot/A0A8C3IXK9 ^@ Similarity ^@ Belongs to the caprin family. http://togogenome.org/gene/8478:CHCHD6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLR3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic25 subfamily.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/8478:LOC101950860 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCL1 ^@ Similarity ^@ Belongs to the NLRP family. http://togogenome.org/gene/8478:EN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Engrailed homeobox family.|||Nucleus http://togogenome.org/gene/8478:HACL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGH7 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/8478:WASHC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IVM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WASH1 family.|||Early endosome membrane|||Endosome membrane|||Recycling endosome membrane http://togogenome.org/gene/8478:ADPRH ^@ http://purl.uniprot.org/uniprot/A0A8C3H838 ^@ Similarity ^@ Belongs to the ADP-ribosylglycohydrolase family. http://togogenome.org/gene/8478:HOXA3 ^@ http://purl.uniprot.org/uniprot/A0A8C3ID10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/8478:LOC101933945 ^@ http://purl.uniprot.org/uniprot/A0A8C3HNG1 ^@ Similarity ^@ Belongs to the CAND family. http://togogenome.org/gene/8478:CASD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IIS8|||http://purl.uniprot.org/uniprot/A0A8C3IM20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PC-esterase family. CASD1 subfamily.|||Membrane http://togogenome.org/gene/8478:TGIF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FPN3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:EHHADH ^@ http://purl.uniprot.org/uniprot/A0A8C3FR15 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/8478:MRPL11 ^@ http://purl.uniprot.org/uniprot/A0A8C3ID83 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/8478:MRPS25 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS25 family.|||Mitochondrion http://togogenome.org/gene/8478:LOC101933514 ^@ http://purl.uniprot.org/uniprot/A0A8C3P9P3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:RDX ^@ http://purl.uniprot.org/uniprot/A0A8C3I7Z4 ^@ Subcellular Location Annotation ^@ Membrane|||cytoskeleton http://togogenome.org/gene/8478:DYNC1LI2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.|||Belongs to the dynein light intermediate chain family.|||Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).|||cytoskeleton http://togogenome.org/gene/8478:LOC101949938 ^@ http://purl.uniprot.org/uniprot/A0A8C3FRT9 ^@ Similarity ^@ Belongs to the COX20 family. http://togogenome.org/gene/8478:MASP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBF5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:FHIP1A ^@ http://purl.uniprot.org/uniprot/A0A8C3IS86 ^@ Similarity ^@ Belongs to the FHIP family. http://togogenome.org/gene/8478:AGK ^@ http://purl.uniprot.org/uniprot/A0A8C3HCI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AGK family.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/8478:LCA5 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCQ6 ^@ Similarity ^@ Belongs to the LCA5 family. http://togogenome.org/gene/8478:NAPB ^@ http://purl.uniprot.org/uniprot/A0A8C3IG37 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP family.|||Membrane|||Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. http://togogenome.org/gene/8478:ONECUT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IY32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/8478:HAGH ^@ http://purl.uniprot.org/uniprot/A0A8C3I867|||http://purl.uniprot.org/uniprot/A0A8C3IBE8|||http://purl.uniprot.org/uniprot/A0A8C3PBD0 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. http://togogenome.org/gene/8478:CEBPZ ^@ http://purl.uniprot.org/uniprot/A0A8C3IH97 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/8478:LOC101944943 ^@ http://purl.uniprot.org/uniprot/A0A8C3IIX5 ^@ Function|||Similarity ^@ Belongs to the KptA/TPT1 family.|||Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate. http://togogenome.org/gene/8478:LOC101947948 ^@ http://purl.uniprot.org/uniprot/A0A8C3IRP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/8478:OPTC ^@ http://purl.uniprot.org/uniprot/A0A8C3HVV1|||http://purl.uniprot.org/uniprot/A0A8C3HY97 ^@ Similarity ^@ Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily. http://togogenome.org/gene/8478:SPIRE1 ^@ http://purl.uniprot.org/uniprot/A0A8C3J068 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the spire family.|||Cell membrane|||Cytoplasmic vesicle membrane|||Membrane|||cytoskeleton http://togogenome.org/gene/8478:GDAP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F2W0 ^@ Similarity ^@ Belongs to the GDAP2 family. http://togogenome.org/gene/8478:TAC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IN40 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tachykinin family.|||Secreted|||Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. http://togogenome.org/gene/8478:RPL35 ^@ http://purl.uniprot.org/uniprot/A0A8C3J0U4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/8478:EIF2D ^@ http://purl.uniprot.org/uniprot/A0A8C3H5Q2 ^@ Similarity ^@ Belongs to the eIF2D family. http://togogenome.org/gene/8478:TRAM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FMC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAM family.|||Membrane http://togogenome.org/gene/8478:GRIN3A ^@ http://purl.uniprot.org/uniprot/A0A8C3FS31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. http://togogenome.org/gene/8478:SLC25A18 ^@ http://purl.uniprot.org/uniprot/A0A8C3IZA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/8478:IRAK1BP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IRAK1BP1 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:LOC101945052 ^@ http://purl.uniprot.org/uniprot/A0A8C3FFG2 ^@ Similarity ^@ Belongs to the NXPE family. http://togogenome.org/gene/8478:CASR ^@ http://purl.uniprot.org/uniprot/A0A8C3F0I1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/8478:AMOTL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H571 ^@ Similarity ^@ Belongs to the angiomotin family. http://togogenome.org/gene/8478:AJAP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2P8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:PEMT ^@ http://purl.uniprot.org/uniprot/A0A8C3PB89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.|||Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.|||Endoplasmic reticulum membrane|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/8478:SLCO5A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FHH3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the organo anion transporter (TC 2.A.60) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:ARPC5 ^@ http://purl.uniprot.org/uniprot/A0A8C3HS73 ^@ Function|||Similarity ^@ Belongs to the ARPC5 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. http://togogenome.org/gene/8478:FAM126B ^@ http://purl.uniprot.org/uniprot/A0A8C3HCC2|||http://purl.uniprot.org/uniprot/A0A8C3P2B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Hyccin family.|||Cell membrane|||Membrane|||cytosol http://togogenome.org/gene/8478:LOC101930993 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICQ0 ^@ Subcellular Location Annotation|||Subunit ^@ Cytoplasmic vesicle membrane|||Interacts with ARF6.|||Membrane|||Presynapse http://togogenome.org/gene/8478:EHD3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCS4|||http://purl.uniprot.org/uniprot/A0A8C3P2M1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Endosome membrane|||Membrane http://togogenome.org/gene/8478:BROX ^@ http://purl.uniprot.org/uniprot/A0A8C3HEK3 ^@ Similarity ^@ Belongs to the BROX family. http://togogenome.org/gene/8478:CNTN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F174 ^@ Similarity ^@ Belongs to the immunoglobulin superfamily. Contactin family. http://togogenome.org/gene/8478:VGLL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IR10|||http://purl.uniprot.org/uniprot/A0A8C3ITC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the vestigial family.|||Nucleus http://togogenome.org/gene/8478:GNPDA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTV6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/8478:ARSI ^@ http://purl.uniprot.org/uniprot/A0A8C3FT83 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/8478:FBLN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJ27 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the fibulin family.|||Homomultimerizes and interacts with various extracellular matrix components.|||Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/8478:DYRK4 ^@ http://purl.uniprot.org/uniprot/A0A8C3FRZ2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. http://togogenome.org/gene/8478:NMBR ^@ http://purl.uniprot.org/uniprot/A0A8C3HWE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:CFAP91 ^@ http://purl.uniprot.org/uniprot/A0A8C3F5N5 ^@ Similarity ^@ Belongs to the CFAP91 family. http://togogenome.org/gene/8478:CAPN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HED9 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/8478:CDKN1A ^@ http://purl.uniprot.org/uniprot/A0A8C3INM2 ^@ Similarity ^@ Belongs to the CDI family. http://togogenome.org/gene/8478:SQSTM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FRQ8 ^@ Subcellular Location Annotation ^@ autophagosome http://togogenome.org/gene/8478:EIF4E3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FFG9 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/8478:GNS ^@ http://purl.uniprot.org/uniprot/A0A8C3F1D9 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfatase family.|||Lysosome|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/8478:MAEL ^@ http://purl.uniprot.org/uniprot/A0A8C3H8G6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the maelstrom family.|||Nucleus|||Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage. http://togogenome.org/gene/8478:HIGD1A ^@ http://purl.uniprot.org/uniprot/A0A8C3H6V6 ^@ Subcellular Location Annotation ^@ Mitochondrion inner membrane http://togogenome.org/gene/8478:DCP1A ^@ http://purl.uniprot.org/uniprot/A0A8C3ICM7 ^@ Similarity ^@ Belongs to the DCP1 family. http://togogenome.org/gene/8478:MBOAT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P6L7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:RSAD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RSAD2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:SULT4A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMU2 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/8478:GALNT10 ^@ http://purl.uniprot.org/uniprot/A0A8C3FB64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:NKIRAS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDD1 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily. http://togogenome.org/gene/8478:HSPA4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HU95 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 70 family.|||Cytoplasm|||Interacts with TJP1/ZO-1. http://togogenome.org/gene/8478:VEGFA ^@ http://purl.uniprot.org/uniprot/A0A8C3IQB8 ^@ Similarity ^@ Belongs to the PDGF/VEGF growth factor family. http://togogenome.org/gene/8478:CNIH3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/8478:ATG16L1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMV0 ^@ Similarity ^@ Belongs to the WD repeat ATG16 family. http://togogenome.org/gene/8478:RPS7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eS7 family.|||centrosome http://togogenome.org/gene/8478:B3GAT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HX31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:HTATSF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPK0 ^@ Similarity ^@ Belongs to the HTATSF1 family. http://togogenome.org/gene/8478:CPEB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FKD3 ^@ Similarity ^@ Belongs to the RRM CPEB family. http://togogenome.org/gene/8478:MXRA8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IF39 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/8478:TSHZ3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HS31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the teashirt C2H2-type zinc-finger protein family.|||Nucleus http://togogenome.org/gene/8478:THUMPD3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HNM0 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. http://togogenome.org/gene/8478:PELI3 ^@ http://purl.uniprot.org/uniprot/A0A8C3ID95 ^@ Similarity ^@ Belongs to the pellino family. http://togogenome.org/gene/8478:POT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the telombin family.|||Nucleus|||telomere http://togogenome.org/gene/8478:TMEM63B ^@ http://purl.uniprot.org/uniprot/A0A8C3IML7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSC1 (TC 1.A.17) family.|||Membrane http://togogenome.org/gene/8478:LOC101953971 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sestrin family.|||Cytoplasm http://togogenome.org/gene/8478:CAVIN4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F746 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAVIN family.|||caveola http://togogenome.org/gene/8478:PRKAB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H6U8 ^@ Function|||Similarity ^@ Belongs to the 5'-AMP-activated protein kinase beta subunit family.|||Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). http://togogenome.org/gene/8478:SEC23B ^@ http://purl.uniprot.org/uniprot/A0A8C3IGA7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC23 subfamily.|||COPII-coated vesicle membrane|||Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.|||Endoplasmic reticulum membrane|||Membrane|||cytosol http://togogenome.org/gene/8478:KPNA4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYV6 ^@ Similarity ^@ Belongs to the importin alpha family. http://togogenome.org/gene/8478:LPIN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HJZ2|||http://purl.uniprot.org/uniprot/A0A8C3HJZ3 ^@ Similarity ^@ Belongs to the lipin family. http://togogenome.org/gene/8478:DCTN5 ^@ http://purl.uniprot.org/uniprot/A0A8C3F8A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.|||cytoskeleton http://togogenome.org/gene/8478:TSPAN31 ^@ http://purl.uniprot.org/uniprot/A0A8C3HY34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/8478:DNAAF4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F9V8 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Dynein axonemal particle|||neuron projection http://togogenome.org/gene/8478:PSPC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PB70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PSPC family.|||Cytoplasm|||Nucleus matrix|||Nucleus speckle|||nucleolus http://togogenome.org/gene/8478:ATL3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJ39 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. http://togogenome.org/gene/8478:ATP6V0A4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HHT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.|||Membrane http://togogenome.org/gene/8478:FAM72A ^@ http://purl.uniprot.org/uniprot/A0A8C3F2Q6 ^@ Similarity ^@ Belongs to the FAM72 family. http://togogenome.org/gene/8478:ACTA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FFU4 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/8478:KIF1B ^@ http://purl.uniprot.org/uniprot/A0A8C3IBE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.|||axon http://togogenome.org/gene/8478:NSUN6 ^@ http://purl.uniprot.org/uniprot/A0A8C3P797 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/8478:DYRK3 ^@ http://purl.uniprot.org/uniprot/A0A8C3F2R8|||http://purl.uniprot.org/uniprot/A0A8C3F443 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. http://togogenome.org/gene/8478:KCNMB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3II96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:MAP3K8 ^@ http://purl.uniprot.org/uniprot/A0A8C3HR15 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. http://togogenome.org/gene/8478:MRPL32 ^@ http://purl.uniprot.org/uniprot/A0A8C3INH9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/8478:YIPF5 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/8478:AP4B1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P7I5 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/8478:LBH ^@ http://purl.uniprot.org/uniprot/A0A8C3HCL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LBH family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:NOC4L ^@ http://purl.uniprot.org/uniprot/A0A8C3IP04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CBF/MAK21 family.|||Nucleus membrane http://togogenome.org/gene/8478:NRXN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3II27 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:TMBIM4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IKF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/8478:TTC4 ^@ http://purl.uniprot.org/uniprot/A0A8C3H6M9 ^@ Similarity ^@ Belongs to the TTC4 family. http://togogenome.org/gene/8478:AQP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FDH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/8478:USP30 ^@ http://purl.uniprot.org/uniprot/A0A8C3FHE1 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/8478:LOC101941250 ^@ http://purl.uniprot.org/uniprot/A0A8C3IK42 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/8478:DDX18 ^@ http://purl.uniprot.org/uniprot/A0A8C3FTR9 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/8478:TAF6L ^@ http://purl.uniprot.org/uniprot/A0A8C3HY50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF6 family.|||Nucleus http://togogenome.org/gene/8478:POU3F4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HM07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family. Class-3 subfamily.|||Nucleus http://togogenome.org/gene/8478:ARHGAP26 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTH2|||http://purl.uniprot.org/uniprot/A0A8C3HUG3 ^@ Subcellular Location Annotation ^@ cytoskeleton|||focal adhesion http://togogenome.org/gene/8478:GPC3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQC1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glypican family.|||Cell membrane|||Cell surface proteoglycan. http://togogenome.org/gene/8478:NXPH1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJH3|||http://purl.uniprot.org/uniprot/A0A8C3IJJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the neurexophilin family.|||May be signaling molecules that resemble neuropeptides.|||Secreted http://togogenome.org/gene/8478:NFASC ^@ http://purl.uniprot.org/uniprot/A0A8C3F658 ^@ Similarity ^@ Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family. http://togogenome.org/gene/8478:GNG3 ^@ http://purl.uniprot.org/uniprot/A0A8C3P958 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/8478:WDR35 ^@ http://purl.uniprot.org/uniprot/A0A8C3PAJ8 ^@ Subcellular Location Annotation ^@ centrosome|||cilium basal body http://togogenome.org/gene/8478:LOC101947474 ^@ http://purl.uniprot.org/uniprot/A0A8C3HM39 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:MMP17 ^@ http://purl.uniprot.org/uniprot/A0A8C3IL70 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10A family.|||Binds 2 Zn(2+) ions per subunit.|||Can bind about 5 Ca(2+) ions per subunit. http://togogenome.org/gene/8478:GNA12 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7V4|||http://purl.uniprot.org/uniprot/A0A8C3I971 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-alpha family. G(12) subfamily.|||Membrane http://togogenome.org/gene/8478:API5 ^@ http://purl.uniprot.org/uniprot/A0A8C3HF00 ^@ Similarity ^@ Belongs to the API5 family. http://togogenome.org/gene/8478:FAM20C ^@ http://purl.uniprot.org/uniprot/A0A8C3I699 ^@ Similarity ^@ Belongs to the FAM20 family. http://togogenome.org/gene/8478:LOC101937286 ^@ http://purl.uniprot.org/uniprot/A0A8C3HU82 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/8478:USP49 ^@ http://purl.uniprot.org/uniprot/A0A8C3P8U6 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/8478:TEX10 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZK5 ^@ Similarity ^@ Belongs to the IPI1/TEX10 family. http://togogenome.org/gene/8478:CPSF4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CPSF4/YTH1 family.|||Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).|||Component of the cleavage and polyadenylation specificity factor (CPSF) complex.|||Nucleus http://togogenome.org/gene/8478:SLC7A6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:LOC101931242 ^@ http://purl.uniprot.org/uniprot/A0A8C3F9G7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Membrane|||The small GTPases Rab are key regulators in vesicle trafficking. http://togogenome.org/gene/8478:LOC101937190 ^@ http://purl.uniprot.org/uniprot/A0A8C3FYA8 ^@ Similarity ^@ Belongs to the strictosidine synthase family. http://togogenome.org/gene/8478:SNX20 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRY4 ^@ Subcellular Location Annotation ^@ Early endosome membrane|||Membrane http://togogenome.org/gene/8478:LHX3 ^@ http://purl.uniprot.org/uniprot/A0A8C3P3C1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:TPST2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9D1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein sulfotransferase family.|||Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.|||Golgi apparatus membrane http://togogenome.org/gene/8478:SMAD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IN54|||http://purl.uniprot.org/uniprot/A0A8C3IP60|||http://purl.uniprot.org/uniprot/A0A8C3IPE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:MED20 ^@ http://purl.uniprot.org/uniprot/A0A8C3HW30 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 20 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/8478:STK40 ^@ http://purl.uniprot.org/uniprot/A0A8C3I154 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.|||Nucleus http://togogenome.org/gene/8478:LOC101935329 ^@ http://purl.uniprot.org/uniprot/A0A8C3H9B1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/8478:LPCAT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P3D6 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/8478:ATP6V1C2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKF9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase C subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits. http://togogenome.org/gene/8478:MRPL3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHJ1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/8478:LOC101951875 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEM6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:PYGM ^@ http://purl.uniprot.org/uniprot/A0A8C3IKU8 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/8478:SLC26A2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FK20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane|||Sulfate transporter which mediates sulfate uptake into chondrocytes in order to maintain adequate sulfation of proteoglycans which is needed for cartilage development. Mediates electroneutral anion exchange of sulfate ions for oxalate ions, sulfate and oxalate ions for chloride and/or hydroxyl ions and chloride ions for bromide, iodide and nitrate ions. The coupling of sulfate transport to both hydroxyl and chloride ions likely serves to ensure transport at both acidic pH when most sulfate uptake is mediated by sulfate-hydroxide exchange and alkaline pH when most sulfate uptake is mediated by sulfate-chloride exchange. Essential for chondrocyte proliferation, differentiation and cell size expansion. http://togogenome.org/gene/8478:TMEM70 ^@ http://purl.uniprot.org/uniprot/A0A8C3FI19 ^@ Similarity ^@ Belongs to the TMEM70 family. http://togogenome.org/gene/8478:TMEM30A ^@ http://purl.uniprot.org/uniprot/A0A8C3IIA8 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/8478:TMEM132C ^@ http://purl.uniprot.org/uniprot/A0A8C3IPY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM132 family.|||Membrane http://togogenome.org/gene/8478:CAPN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IH21 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/8478:LOC101945657 ^@ http://purl.uniprot.org/uniprot/A0A8C3FY33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPEG family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:MOSPD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IR63 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:TFEB ^@ http://purl.uniprot.org/uniprot/A0A8C3HVX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MiT/TFE family.|||Nucleus http://togogenome.org/gene/8478:PTH1R ^@ http://purl.uniprot.org/uniprot/A0A8C3H5Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:PHYKPL ^@ http://purl.uniprot.org/uniprot/A0A8C3FP53 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/8478:LOC101938305 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/8478:ADHFE1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I999 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.|||Mitochondrion http://togogenome.org/gene/8478:LAMTOR5 ^@ http://purl.uniprot.org/uniprot/A0A8C3F4D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMTOR5 family.|||Lysosome http://togogenome.org/gene/8478:SZRD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HAX8 ^@ Similarity ^@ Belongs to the SZRD1 family. http://togogenome.org/gene/8478:C1GALT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PDN1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.|||Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.|||Membrane http://togogenome.org/gene/8478:ADGB ^@ http://purl.uniprot.org/uniprot/A0A8C3HTM8 ^@ Caution|||Similarity ^@ Belongs to the globin family.|||Belongs to the peptidase C2 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:CNIH4 ^@ http://purl.uniprot.org/uniprot/A0A8C3P374 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/8478:CHAC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HIG8 ^@ Function|||Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.|||Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. http://togogenome.org/gene/8478:ZC3H12C ^@ http://purl.uniprot.org/uniprot/A0A8C3PBB6 ^@ Similarity ^@ Belongs to the ZC3H12 family. http://togogenome.org/gene/8478:RAPGEF6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMF0|||http://purl.uniprot.org/uniprot/A0A8C3PE83 ^@ Similarity ^@ Belongs to the RAPGEF2 family. http://togogenome.org/gene/8478:ACTB ^@ http://purl.uniprot.org/uniprot/A0A8C3I6V8 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/8478:TMEM53 ^@ http://purl.uniprot.org/uniprot/A0A8C3F7U9|||http://purl.uniprot.org/uniprot/A0A8C3F825 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM53 family.|||Membrane|||Nucleus outer membrane http://togogenome.org/gene/8478:SFXN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FKD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/8478:FGF18 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAW5 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/8478:CBWD3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IN97 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/8478:LOC101936307 ^@ http://purl.uniprot.org/uniprot/A0A8C3FKL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PPP phosphatase family.|||Cytoplasm http://togogenome.org/gene/8478:STXBP5 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTL9|||http://purl.uniprot.org/uniprot/A0A8C3HTN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat L(2)GL family.|||Cell membrane|||Cytoplasm|||Membrane http://togogenome.org/gene/8478:ALG6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HL94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ALG6/ALG8 glucosyltransferase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:MUS81 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGX4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XPF family.|||Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).|||Interacts with EME1.|||Nucleus http://togogenome.org/gene/8478:POU6F1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I104 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/8478:ALDOB ^@ http://purl.uniprot.org/uniprot/A0A8C3HA87 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/8478:ATG4C ^@ http://purl.uniprot.org/uniprot/A0A8C3HL31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C54 family.|||Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.|||Cytoplasm http://togogenome.org/gene/8478:ABCA3 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:GAL3ST3 ^@ http://purl.uniprot.org/uniprot/A0A8C3ID52 ^@ Similarity ^@ Belongs to the galactose-3-O-sulfotransferase family. http://togogenome.org/gene/8478:TM4SF19 ^@ http://purl.uniprot.org/uniprot/A0A8C3I988 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the L6 tetraspanin family.|||Membrane http://togogenome.org/gene/8478:MC4R ^@ http://purl.uniprot.org/uniprot/A0A8C3F4H6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). http://togogenome.org/gene/8478:KCNJ5 ^@ http://purl.uniprot.org/uniprot/A0A8C3ITU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.|||Membrane http://togogenome.org/gene/8478:PTN ^@ http://purl.uniprot.org/uniprot/A0A8C3FXP8 ^@ Similarity ^@ Belongs to the pleiotrophin family. http://togogenome.org/gene/8478:QPCT ^@ http://purl.uniprot.org/uniprot/A0A8C3IH87 ^@ Similarity ^@ Belongs to the glutaminyl-peptide cyclotransferase family. http://togogenome.org/gene/8478:ZPR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8J6 ^@ Similarity ^@ Belongs to the ZPR1 family. http://togogenome.org/gene/8478:STK10 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.|||Cell membrane http://togogenome.org/gene/8478:CBLB ^@ http://purl.uniprot.org/uniprot/A0A8C3FAD4 ^@ Domain|||Function ^@ E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.|||The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain. http://togogenome.org/gene/8478:PDLIM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEJ7 ^@ Subcellular Location Annotation ^@ Z line http://togogenome.org/gene/8478:ANXA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I4V9 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Basolateral cell membrane|||Belongs to the annexin family.|||Cell membrane|||Cytoplasm|||Lateral cell membrane|||Membrane|||Nucleus|||The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.|||cilium http://togogenome.org/gene/8478:LOC101954012 ^@ http://purl.uniprot.org/uniprot/A0A8C3FPL3 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/8478:LOC101948875 ^@ http://purl.uniprot.org/uniprot/A0A8C3HP57 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cyclin-dependent kinase 5 activator family.|||Cell membrane|||Heterodimer of a catalytic subunit and a regulatory subunit.|||Membrane http://togogenome.org/gene/8478:DENND6A ^@ http://purl.uniprot.org/uniprot/A0A8C3HE57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DENND6 family.|||Recycling endosome http://togogenome.org/gene/8478:CITED2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CITED family.|||Nucleus http://togogenome.org/gene/8478:TNFSF10 ^@ http://purl.uniprot.org/uniprot/A0A8C3HR39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tumor necrosis factor family.|||Membrane|||Secreted http://togogenome.org/gene/8478:CD28 ^@ http://purl.uniprot.org/uniprot/A0A8C3FVD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:TUBB6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IZ77 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/8478:MYBL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I922 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:HNRNPAB ^@ http://purl.uniprot.org/uniprot/A0A8C3FNW3|||http://purl.uniprot.org/uniprot/A0A8C3H9S6 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/8478:MRPL44 ^@ http://purl.uniprot.org/uniprot/A0A8C3I5Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.|||Mitochondrion http://togogenome.org/gene/8478:CSF1R ^@ http://purl.uniprot.org/uniprot/A0A8C3FVQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:LOC101941771 ^@ http://purl.uniprot.org/uniprot/A0A8C3I1S3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alpha/beta interferon family.|||Has antiviral activities.|||Secreted http://togogenome.org/gene/8478:CREB5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFJ5|||http://purl.uniprot.org/uniprot/A0A8C3PCA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bZIP family.|||Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.|||Binds to the cAMP response element and activates transcription.|||Nucleus http://togogenome.org/gene/8478:MTHFR ^@ http://purl.uniprot.org/uniprot/A0A8C3IEK2 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/8478:LOC101953520 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:NSG2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H8Y7 ^@ Similarity ^@ Belongs to the NSG family. http://togogenome.org/gene/8478:ACAD10 ^@ http://purl.uniprot.org/uniprot/A0A8C3F918 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/8478:ETV7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/8478:LOC101946313 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFW0|||http://purl.uniprot.org/uniprot/A0A8C3IGB8|||http://purl.uniprot.org/uniprot/A0A8C3IGS1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:LOC101951236 ^@ http://purl.uniprot.org/uniprot/A0A8C3IC84 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:LOC101946342 ^@ http://purl.uniprot.org/uniprot/A0A8C3HXK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM47 family.|||Membrane http://togogenome.org/gene/8478:ETF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9F9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm http://togogenome.org/gene/8478:RPN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HL49 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OST1 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/8478:HTR4 ^@ http://purl.uniprot.org/uniprot/A0A8C3FSK9|||http://purl.uniprot.org/uniprot/A0A8C3H9L4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Endosome|||Membrane|||This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. http://togogenome.org/gene/8478:SLC4A7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDJ7|||http://purl.uniprot.org/uniprot/A0A8C3IDK7 ^@ Similarity|||Subcellular Location Annotation ^@ Basolateral cell membrane|||Belongs to the anion exchanger (TC 2.A.31) family.|||Cell membrane|||Lateral cell membrane|||Membrane http://togogenome.org/gene/8478:MPHOSPH10 ^@ http://purl.uniprot.org/uniprot/A0A8C3FY80 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MPP10 family.|||Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.|||nucleolus http://togogenome.org/gene/8478:ACAA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEG8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/8478:PDK4 ^@ http://purl.uniprot.org/uniprot/A0A8C3PDN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDK/BCKDK protein kinase family.|||Mitochondrion matrix http://togogenome.org/gene/8478:GDA ^@ http://purl.uniprot.org/uniprot/A0A8C3I5Q3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. http://togogenome.org/gene/8478:HSPB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FWB6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/8478:INO80 ^@ http://purl.uniprot.org/uniprot/A0A8C3HIQ5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.|||Belongs to the SNF2/RAD54 helicase family.|||Component of the INO80 chromatin-remodeling complex.|||Nucleus|||The DBINO region is involved in binding to DNA. http://togogenome.org/gene/8478:NUDT7 ^@ http://purl.uniprot.org/uniprot/A0A8C3FXU5 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. PCD1 subfamily. http://togogenome.org/gene/8478:GADL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDN3 ^@ Similarity|||Subunit ^@ Belongs to the group II decarboxylase family.|||Homodimer. http://togogenome.org/gene/8478:ASTE1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDD2 ^@ Similarity ^@ Belongs to the asteroid family. http://togogenome.org/gene/8478:ACTN3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IIC3 ^@ Similarity ^@ Belongs to the alpha-actinin family. http://togogenome.org/gene/8478:FOXC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJC6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:LOC101953804 ^@ http://purl.uniprot.org/uniprot/A0A8C3HU83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:COL4A6 ^@ http://purl.uniprot.org/uniprot/A0A8C3F3C4 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.|||basement membrane http://togogenome.org/gene/8478:STYXL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FEE9 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. http://togogenome.org/gene/8478:GTPBP8 ^@ http://purl.uniprot.org/uniprot/A0A8C3H6W5 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. http://togogenome.org/gene/8478:SLC20A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IN06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter. http://togogenome.org/gene/8478:REXO4 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8E5 ^@ Similarity ^@ Belongs to the REXO4 family. http://togogenome.org/gene/8478:LOC101946465 ^@ http://purl.uniprot.org/uniprot/A0A8C3HXP1 ^@ Similarity ^@ Belongs to the phospholipase D family. http://togogenome.org/gene/8478:PDE7B ^@ http://purl.uniprot.org/uniprot/A0A8C3HWQ9|||http://purl.uniprot.org/uniprot/A0A8C3HXU5 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/8478:CLDN11 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTB7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/8478:BCL2L13 ^@ http://purl.uniprot.org/uniprot/A0A8C3IYZ1 ^@ Similarity ^@ Belongs to the Bcl-2 family. http://togogenome.org/gene/8478:NXT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F056 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/8478:PDGFA ^@ http://purl.uniprot.org/uniprot/A0A8C3I6B6|||http://purl.uniprot.org/uniprot/A0A8C3I711|||http://purl.uniprot.org/uniprot/A0A8C3PAY0 ^@ Similarity ^@ Belongs to the PDGF/VEGF growth factor family. http://togogenome.org/gene/8478:NAV2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HK45 ^@ Similarity ^@ Belongs to the Nav/unc-53 family. http://togogenome.org/gene/8478:WIF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1I2 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/8478:TTC39B ^@ http://purl.uniprot.org/uniprot/A0A8C3IN13|||http://purl.uniprot.org/uniprot/A0A8C3INS2 ^@ Similarity ^@ Belongs to the TTC39 family. http://togogenome.org/gene/8478:ADCY9 ^@ http://purl.uniprot.org/uniprot/A0A8C3IRY3 ^@ Similarity ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. http://togogenome.org/gene/8478:ERN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F3F0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:RAB39B ^@ http://purl.uniprot.org/uniprot/A0A8C3H586 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:MED9 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9Y2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 9 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/8478:TP73 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2N3|||http://purl.uniprot.org/uniprot/A0A8C3I3E4|||http://purl.uniprot.org/uniprot/A0A8C3PA74 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the p53 family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Found in a complex with p53/TP53 and CABLES1.|||Nucleus|||Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. http://togogenome.org/gene/8478:IGFBP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P8B1 ^@ Caution|||Function|||Subcellular Location Annotation|||Subunit ^@ Binds equally well IGF1 and IGF2.|||IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/8478:USP10 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHP8|||http://purl.uniprot.org/uniprot/A0A8C3IJG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C19 family. USP10 subfamily.|||Cytoplasm http://togogenome.org/gene/8478:SLC39A12 ^@ http://purl.uniprot.org/uniprot/A0A8C3HND7|||http://purl.uniprot.org/uniprot/A0A8C3HPS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family.|||Membrane http://togogenome.org/gene/8478:SGSM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBP2 ^@ Similarity ^@ Belongs to the RUTBC family. http://togogenome.org/gene/8478:SDF4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CREC family.|||Golgi apparatus lumen http://togogenome.org/gene/8478:PRRX1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P514 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:SNAP23 ^@ http://purl.uniprot.org/uniprot/A0A8C3HGL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP-25 family.|||synaptosome http://togogenome.org/gene/8478:LOC101931482 ^@ http://purl.uniprot.org/uniprot/A0A8C3FMH9 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/8478:CC2D1B ^@ http://purl.uniprot.org/uniprot/A0A8C3HN16 ^@ Similarity ^@ Belongs to the CC2D1 family. http://togogenome.org/gene/8478:ARF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F337 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/8478:CEBPG ^@ http://purl.uniprot.org/uniprot/A0A8C3F1B4 ^@ Similarity ^@ Belongs to the bZIP family. C/EBP subfamily. http://togogenome.org/gene/8478:IL1RL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJI2 ^@ Similarity ^@ Belongs to the interleukin-1 receptor family. http://togogenome.org/gene/8478:CHD5 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family.|||Nucleus http://togogenome.org/gene/8478:ATP6V1A ^@ http://purl.uniprot.org/uniprot/A0A8C3F1I6 ^@ Similarity ^@ Belongs to the ATPase alpha/beta chains family. http://togogenome.org/gene/8478:LOC101952321 ^@ http://purl.uniprot.org/uniprot/A0A8C3F736 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:LOC101938211 ^@ http://purl.uniprot.org/uniprot/A0A8C3FGE2 ^@ Similarity ^@ Belongs to the MS4A family. http://togogenome.org/gene/8478:SLC29A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PE86 ^@ Similarity|||Subcellular Location Annotation ^@ Basolateral cell membrane|||Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Lateral cell membrane|||Membrane http://togogenome.org/gene/8478:GINS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJ49 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS2/PSF2 family.|||Chromosome|||Component of the GINS complex.|||Nucleus http://togogenome.org/gene/8478:CA8 ^@ http://purl.uniprot.org/uniprot/A0A8C3II29 ^@ Similarity ^@ Belongs to the alpha-carbonic anhydrase family. http://togogenome.org/gene/8478:DENR ^@ http://purl.uniprot.org/uniprot/A0A8C3IR70 ^@ Similarity ^@ Belongs to the DENR family. http://togogenome.org/gene/8478:SLC35C1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HF89 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:CNEP1R1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNEP1R1 family.|||Cytoplasm|||Membrane|||Nucleus membrane http://togogenome.org/gene/8478:LOC101939147 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWF2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. http://togogenome.org/gene/8478:GLIS3 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEC6 ^@ Similarity ^@ Belongs to the GLI C2H2-type zinc-finger protein family. http://togogenome.org/gene/8478:LOC101939406 ^@ http://purl.uniprot.org/uniprot/A0A8C3P5N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM151 family.|||Membrane http://togogenome.org/gene/8478:LOC101932119 ^@ http://purl.uniprot.org/uniprot/A0A8C3F6L3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/8478:SPARC ^@ http://purl.uniprot.org/uniprot/A0A8C3FTI2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.|||Belongs to the SPARC family.|||Membrane|||basement membrane http://togogenome.org/gene/8478:VGLL4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HU46 ^@ Function|||Similarity ^@ Belongs to the vestigial family.|||May act as a specific coactivator for the mammalian TEFs. http://togogenome.org/gene/8478:DVL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCK1 ^@ Similarity ^@ Belongs to the DSH family. http://togogenome.org/gene/8478:FOXP4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HX79 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:NDST1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HAL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 1 family. NDST subfamily.|||Membrane http://togogenome.org/gene/8478:LOC101953089 ^@ http://purl.uniprot.org/uniprot/A0A8C3IL06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HARBI1 family.|||Cytoplasm|||Nucleus|||Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity. http://togogenome.org/gene/8478:ACTL6A ^@ http://purl.uniprot.org/uniprot/A0A8C3PFJ5 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/8478:WNT16 ^@ http://purl.uniprot.org/uniprot/A0A8C3FM65 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/8478:CUX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F6X6|||http://purl.uniprot.org/uniprot/A0A8C3FAF1|||http://purl.uniprot.org/uniprot/A0A8C3H6H8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/8478:GDE1 ^@ http://purl.uniprot.org/uniprot/A0A8C3G076 ^@ Similarity ^@ Belongs to the glycerophosphoryl diester phosphodiesterase family. http://togogenome.org/gene/8478:NOC2L ^@ http://purl.uniprot.org/uniprot/A0A8C3IB39 ^@ Similarity ^@ Belongs to the NOC2 family. http://togogenome.org/gene/8478:TRIM71 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDW5 ^@ Similarity ^@ Belongs to the TRIM/RBCC family. http://togogenome.org/gene/8478:SLC7A3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:TIGD3 ^@ http://purl.uniprot.org/uniprot/A0A8C3PD60 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:AURKAIP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCK3 ^@ Similarity ^@ Belongs to the mitochondrion-specific ribosomal protein mS38 family. http://togogenome.org/gene/8478:ARPC1B ^@ http://purl.uniprot.org/uniprot/A0A8C3PB64 ^@ Function|||Similarity ^@ Belongs to the WD repeat ARPC1 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. http://togogenome.org/gene/8478:ACSS3 ^@ http://purl.uniprot.org/uniprot/A0A8C3EXQ3 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/8478:LRP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3F0X1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:DISP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDT9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:LOC101954184 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDJ6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/8478:MECOM ^@ http://purl.uniprot.org/uniprot/A0A8C3HRP2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:CCNL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZS4 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/8478:METTL6 ^@ http://purl.uniprot.org/uniprot/A0A8C3ID94 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. METL family.|||S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/8478:ARHGEF9 ^@ http://purl.uniprot.org/uniprot/A0A8C3H600|||http://purl.uniprot.org/uniprot/A0A8C3H6F2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.|||Cytoplasm|||Interacts with GPHN.|||Postsynaptic density http://togogenome.org/gene/8478:PDE4B ^@ http://purl.uniprot.org/uniprot/A0A8C3F271 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/8478:AASDHPPT ^@ http://purl.uniprot.org/uniprot/A0A8C3F0D4 ^@ Similarity ^@ Belongs to the P-Pant transferase superfamily. AcpS family. http://togogenome.org/gene/8478:ROCK2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HK11|||http://purl.uniprot.org/uniprot/A0A8C3P6I9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.|||Cell membrane|||Cytoplasm|||Membrane|||centrosome http://togogenome.org/gene/8478:SLC6A6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMA6|||http://purl.uniprot.org/uniprot/A0A8C3HMV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:GDPD5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IWI5|||http://purl.uniprot.org/uniprot/A0A8C3J0R0 ^@ Similarity ^@ Belongs to the glycerophosphoryl diester phosphodiesterase family. http://togogenome.org/gene/8478:MRPL20 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHR9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family. http://togogenome.org/gene/8478:KCNV2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQU3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:LXN ^@ http://purl.uniprot.org/uniprot/A0A8C3P9G1 ^@ Similarity ^@ Belongs to the protease inhibitor I47 (latexin) family. http://togogenome.org/gene/8478:UBAP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FDZ9|||http://purl.uniprot.org/uniprot/A0A8C3FJL0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:STK32A ^@ http://purl.uniprot.org/uniprot/A0A8C3P9W5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:EXOSC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRP4 family.|||Cytoplasm http://togogenome.org/gene/8478:ELAC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IRN2 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/8478:ATPAF2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8Q8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP12 family.|||Mitochondrion http://togogenome.org/gene/8478:NINJ1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ninjurin family.|||Membrane http://togogenome.org/gene/8478:ERH ^@ http://purl.uniprot.org/uniprot/A0A8C3IAR7 ^@ Function|||Similarity ^@ Belongs to the E(R) family.|||May have a role in the cell cycle. http://togogenome.org/gene/8478:WFIKKN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WFIKKN family.|||Secreted http://togogenome.org/gene/8478:FAM163A ^@ http://purl.uniprot.org/uniprot/A0A8C3ISE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM163 family.|||Membrane http://togogenome.org/gene/8478:RPS17 ^@ http://purl.uniprot.org/uniprot/A0A8C3FFK7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/8478:SLC6A17 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1P6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/8478:THRB ^@ http://purl.uniprot.org/uniprot/A0A8C3IDF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.|||Nucleus http://togogenome.org/gene/8478:PHACTR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HV71|||http://purl.uniprot.org/uniprot/A0A8C3HVA5|||http://purl.uniprot.org/uniprot/A0A8C3HWB8 ^@ Similarity|||Subunit ^@ Belongs to the phosphatase and actin regulator family.|||Binds PPP1CA and actin. http://togogenome.org/gene/8478:MMP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDN2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M10A family.|||Binds 2 Zn(2+) ions per subunit.|||Can bind about 5 Ca(2+) ions per subunit.|||extracellular matrix http://togogenome.org/gene/8478:SLC25A33 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/8478:BSCL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HXS1 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:MPPE1 ^@ http://purl.uniprot.org/uniprot/A0A8C3J1U0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallophosphoesterase superfamily. MPPE1 family.|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Membrane|||Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.|||cis-Golgi network membrane http://togogenome.org/gene/8478:TRUB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IR42 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruB family. http://togogenome.org/gene/8478:C2H7orf25 ^@ http://purl.uniprot.org/uniprot/A0A8C3PDZ1 ^@ Similarity ^@ Belongs to the UPF0415 family. http://togogenome.org/gene/8478:KIF9 ^@ http://purl.uniprot.org/uniprot/A0A8C3HPC6 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/8478:MARS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HD82 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/8478:GRIK3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I124 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. http://togogenome.org/gene/8478:MRRF ^@ http://purl.uniprot.org/uniprot/A0A8C3FUW7 ^@ Function|||Similarity ^@ Belongs to the RRF family.|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/8478:IMPA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PGJ0 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/8478:TAMM41 ^@ http://purl.uniprot.org/uniprot/A0A8C3EY95|||http://purl.uniprot.org/uniprot/A0A8C3F1K1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TAM41 family.|||Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:MCEE ^@ http://purl.uniprot.org/uniprot/A0A8C3FWX2 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/8478:SPCS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H553 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS2 family.|||Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:BMP5 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICG8 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/8478:RNF168 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9Z7 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNF168 family.|||Nucleus|||The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs). http://togogenome.org/gene/8478:BBS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HD40 ^@ Subcellular Location Annotation ^@ centriolar satellite|||cilium membrane http://togogenome.org/gene/8478:TTC21A ^@ http://purl.uniprot.org/uniprot/A0A8C3HZU4 ^@ Similarity ^@ Belongs to the TTC21 family. http://togogenome.org/gene/8478:RPS8 ^@ http://purl.uniprot.org/uniprot/A0A8C3F8Y8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS8 family. http://togogenome.org/gene/8478:BDNF ^@ http://purl.uniprot.org/uniprot/A0A8C3FAT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NGF-beta family.|||Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.|||Secreted http://togogenome.org/gene/8478:ABI2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FP23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABI family.|||cytoskeleton|||filopodium|||lamellipodium http://togogenome.org/gene/8478:PARD3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAR3 family.|||Cell junction|||Endomembrane system http://togogenome.org/gene/8478:NIP7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IT49 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NIP7 family.|||Interacts with pre-ribosome complex.|||Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.|||nucleolus http://togogenome.org/gene/8478:ARPC1A ^@ http://purl.uniprot.org/uniprot/A0A8C3I7H1 ^@ Function|||Similarity ^@ Belongs to the WD repeat ARPC1 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. http://togogenome.org/gene/8478:STX6 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Golgi apparatus membrane http://togogenome.org/gene/8478:TMEM255A ^@ http://purl.uniprot.org/uniprot/A0A8C3PB18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM255 family.|||Membrane http://togogenome.org/gene/8478:LOC101951432 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZM6|||http://purl.uniprot.org/uniprot/A0A8C3H529 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:PLCG2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IKM1 ^@ Function ^@ Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. http://togogenome.org/gene/8478:ZCCHC8 ^@ http://purl.uniprot.org/uniprot/A0A8C3F5H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZCCHC8 family.|||nucleoplasm http://togogenome.org/gene/8478:LHFPL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P8M4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:AVPR1A ^@ http://purl.uniprot.org/uniprot/A0A8C3F502 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:SDHAF3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I LYR family. SDHAF3 subfamily.|||Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.|||Mitochondrion matrix|||Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1. http://togogenome.org/gene/8478:SLC15A4 ^@ http://purl.uniprot.org/uniprot/A0A8C3PE12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/8478:TSR3 ^@ http://purl.uniprot.org/uniprot/A0A8C3F6U2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.|||Belongs to the TDD superfamily. TSR3 family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:CHST2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.|||Membrane http://togogenome.org/gene/8478:TRAK2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HC89|||http://purl.uniprot.org/uniprot/A0A8C3P274 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the milton family.|||Early endosome|||Mitochondrion http://togogenome.org/gene/8478:LOC101934489 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDK7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.|||Homodimer; disulfide-linked.|||Membrane http://togogenome.org/gene/8478:LOC101933753 ^@ http://purl.uniprot.org/uniprot/A0A8C3IH09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:PEPD ^@ http://purl.uniprot.org/uniprot/A0A8C3F2A2 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/8478:REN ^@ http://purl.uniprot.org/uniprot/A0A8C3P8T5 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/8478:KCTD20 ^@ http://purl.uniprot.org/uniprot/A0A8C3PE80 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:CHL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IYX1|||http://purl.uniprot.org/uniprot/A0A8C3IZ02|||http://purl.uniprot.org/uniprot/A0A8C3J1T6 ^@ Similarity ^@ Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family. http://togogenome.org/gene/8478:LAMB3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8E6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:CNOT6 ^@ http://purl.uniprot.org/uniprot/A0A8C3FPA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCR4/nocturin family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:OXSM ^@ http://purl.uniprot.org/uniprot/A0A8C3ICR6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/8478:LOC101950054 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGW0 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. http://togogenome.org/gene/8478:HS3ST2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F4X7 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/8478:LOC101942029 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2V2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alpha/beta interferon family.|||Has antiviral activities.|||Secreted http://togogenome.org/gene/8478:DMRT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IS47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DMRT family.|||Nucleus http://togogenome.org/gene/8478:LOC101931671 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBM4 ^@ Similarity ^@ Belongs to the CTNNBIP1 family. http://togogenome.org/gene/8478:HDAC10 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8C4 ^@ Similarity ^@ Belongs to the histone deacetylase family. HD type 2 subfamily. http://togogenome.org/gene/8478:LOC101941396 ^@ http://purl.uniprot.org/uniprot/A0A8C3ILG2 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/8478:VDAC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPR3 ^@ Similarity ^@ Belongs to the eukaryotic mitochondrial porin family. http://togogenome.org/gene/8478:FZD3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I4U7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:CHPT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F843 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/8478:AGPAT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDX0 ^@ Domain|||Function|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/8478:CDT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCZ0 ^@ Similarity ^@ Belongs to the Cdt1 family. http://togogenome.org/gene/8478:DUSP16 ^@ http://purl.uniprot.org/uniprot/A0A8C3H5C8 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. http://togogenome.org/gene/8478:CDK4 ^@ http://purl.uniprot.org/uniprot/A0A8C3P992 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:GLIS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEZ6 ^@ Similarity ^@ Belongs to the GLI C2H2-type zinc-finger protein family. http://togogenome.org/gene/8478:GABRA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3H9B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/8478:KAT5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MYST (SAS/MOZ) family.|||Nucleus http://togogenome.org/gene/8478:MEOX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAW0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:STEAP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STEAP family.|||Endosome membrane|||Membrane http://togogenome.org/gene/8478:USP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HX91 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/8478:SLC6A19 ^@ http://purl.uniprot.org/uniprot/A0A8C3HSA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/8478:CHDH ^@ http://purl.uniprot.org/uniprot/A0A8C3PBK9 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/8478:NIF3L1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCD9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family.|||Cytoplasm|||Homodimer. Interacts with COPS2. Interacts with THOC7.|||May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.|||Nucleus http://togogenome.org/gene/8478:FIGNL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTI8 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/8478:CDX1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HAK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Caudal homeobox family.|||Nucleus http://togogenome.org/gene/8478:LOC101937211 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glucagon family.|||Secreted http://togogenome.org/gene/8478:TMEM116 ^@ http://purl.uniprot.org/uniprot/A0A8C3F7T1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:MYD88 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZA1 ^@ Function|||Subcellular Location Annotation ^@ Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.|||Cytoplasm http://togogenome.org/gene/8478:LOC101934902 ^@ http://purl.uniprot.org/uniprot/A0A8C3FQ96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:PALS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FKV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAGUK family.|||Cell membrane|||tight junction http://togogenome.org/gene/8478:LOC101931070 ^@ http://purl.uniprot.org/uniprot/A0A8C3FMC6|||http://purl.uniprot.org/uniprot/A0A8C3FUS6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.|||Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. http://togogenome.org/gene/8478:LOC101938107 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJX8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway. http://togogenome.org/gene/8478:GPI ^@ http://purl.uniprot.org/uniprot/A0A8C3F534 ^@ Similarity ^@ Belongs to the GPI family. http://togogenome.org/gene/8478:HOXA5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/8478:SLC25A36 ^@ http://purl.uniprot.org/uniprot/A0A8C3I223|||http://purl.uniprot.org/uniprot/A0A8C3PA45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/8478:BCO1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJ10 ^@ Cofactor|||Similarity ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/8478:KIF26B ^@ http://purl.uniprot.org/uniprot/A0A8C3FQ64|||http://purl.uniprot.org/uniprot/A0A8C3FXN8 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/8478:PAIP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FMG6 ^@ Similarity ^@ Belongs to the PAIP2 family. http://togogenome.org/gene/8478:HLX ^@ http://purl.uniprot.org/uniprot/A0A8C3F0G3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:CCDC85B ^@ http://purl.uniprot.org/uniprot/A0A8C3IFB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCDC85 family.|||adherens junction http://togogenome.org/gene/8478:GRM7 ^@ http://purl.uniprot.org/uniprot/A0A8C3HML0|||http://purl.uniprot.org/uniprot/A0A8C3HML8|||http://purl.uniprot.org/uniprot/A0A8C3HN49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:PTTG1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FKK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the securin family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:POP4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRZ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic/archaeal RNase P protein component 1 family.|||Component of nuclear RNase P and RNase MRP.|||Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.|||nucleolus http://togogenome.org/gene/8478:ALDH8A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWS0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/8478:C7H18orf25 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPJ4|||http://purl.uniprot.org/uniprot/A0A8C3IPP7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:TATDN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMC1 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/8478:VPS4A ^@ http://purl.uniprot.org/uniprot/A0A8C3PFJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Endosome membrane|||Late endosome membrane|||Membrane http://togogenome.org/gene/8478:NGLY1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDD7|||http://purl.uniprot.org/uniprot/A0A8C3IFW8|||http://purl.uniprot.org/uniprot/A0A8C3IGR8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglutaminase-like superfamily. PNGase family.|||Cytoplasm|||Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins. http://togogenome.org/gene/8478:KCNE4 ^@ http://purl.uniprot.org/uniprot/A0A8C3I354 ^@ Similarity ^@ Belongs to the potassium channel KCNE family. http://togogenome.org/gene/8478:CSTF2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKZ1|||http://purl.uniprot.org/uniprot/A0A8C3HM25 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:ACAT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I0D4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/8478:GABRB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FKR9|||http://purl.uniprot.org/uniprot/A0A8C3FLU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/8478:TCEANC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F6Y7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:PTK2B ^@ http://purl.uniprot.org/uniprot/A0A8C3IC72|||http://purl.uniprot.org/uniprot/A0A8C3IFN9 ^@ Subcellular Location Annotation ^@ Cell membrane|||focal adhesion http://togogenome.org/gene/8478:PLIN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I107 ^@ Similarity ^@ Belongs to the perilipin family. http://togogenome.org/gene/8478:GPR39 ^@ http://purl.uniprot.org/uniprot/A0A8C3FSN3 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:LHX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IYL9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:APOA4 ^@ http://purl.uniprot.org/uniprot/A0A8C3I6B4 ^@ Similarity ^@ Belongs to the apolipoprotein A1/A4/E family. http://togogenome.org/gene/8478:TRPV4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IC57 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:NLGN3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTN9|||http://purl.uniprot.org/uniprot/A0A8C3HU76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type-B carboxylesterase/lipase family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:SLCO2A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8R7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the organo anion transporter (TC 2.A.60) family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:NAA40 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHA8|||http://purl.uniprot.org/uniprot/A0A8C3IHB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. NAA40 subfamily.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:LOC101945150 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZ49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARL2BP family.|||Cytoplasm|||Mitochondrion intermembrane space|||Nucleus|||Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.|||centrosome|||cilium basal body http://togogenome.org/gene/8478:EEF2K ^@ http://purl.uniprot.org/uniprot/A0A8C3I255|||http://purl.uniprot.org/uniprot/A0A8C3I2W1 ^@ Activity Regulation|||Similarity|||Subunit ^@ Belongs to the protein kinase superfamily. Alpha-type protein kinase family.|||Monomer or homodimer.|||Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent. http://togogenome.org/gene/8478:SMC4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family.|||Chromosome|||Nucleus http://togogenome.org/gene/8478:DBX1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKG9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:HTR1B ^@ http://purl.uniprot.org/uniprot/A0A8C3IF35 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Homodimer. Heterodimer with HTR1D.|||Membrane http://togogenome.org/gene/8478:HSPB7 ^@ http://purl.uniprot.org/uniprot/A0A8C3HBB9 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/8478:LRRC42 ^@ http://purl.uniprot.org/uniprot/A0A8C3F6V6 ^@ Similarity ^@ Belongs to the LRRC42 family. http://togogenome.org/gene/8478:LOC101930942 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0389 family.|||Membrane http://togogenome.org/gene/8478:KATNA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTG6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.|||Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.|||Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.|||Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.|||Cytoplasm|||centrosome|||spindle|||spindle pole http://togogenome.org/gene/8478:CSNK1G1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FEP5|||http://purl.uniprot.org/uniprot/A0A8C3H826 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. http://togogenome.org/gene/8478:AGO3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZU5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the argonaute family. Ago subfamily.|||P-body|||Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. http://togogenome.org/gene/8478:SMG7 ^@ http://purl.uniprot.org/uniprot/A0A8C3HQI4 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||Plays a role in nonsense-mediated mRNA decay. http://togogenome.org/gene/8478:LOC101934695 ^@ http://purl.uniprot.org/uniprot/A0A8C3INF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/8478:GPSM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDL9|||http://purl.uniprot.org/uniprot/A0A8C3HDP9|||http://purl.uniprot.org/uniprot/A0A8C3P3B5 ^@ Similarity ^@ Belongs to the GPSM family. http://togogenome.org/gene/8478:STRADB ^@ http://purl.uniprot.org/uniprot/A0A8C3HC83 ^@ Function|||Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.|||Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. http://togogenome.org/gene/8478:YAF2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HPS2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:ACER2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I0Z0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alkaline ceramidase family.|||Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:BTD ^@ http://purl.uniprot.org/uniprot/A0A8C3ID15 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family. http://togogenome.org/gene/8478:GSN ^@ http://purl.uniprot.org/uniprot/A0A8C3FTM3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the villin/gelsolin family.|||Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.|||cytoskeleton http://togogenome.org/gene/8478:NMNAT3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I525 ^@ Similarity ^@ Belongs to the eukaryotic NMN adenylyltransferase family. http://togogenome.org/gene/8478:PLPPR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FRP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/8478:TPD52L1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZN4|||http://purl.uniprot.org/uniprot/A0A8C3HZN7|||http://purl.uniprot.org/uniprot/A0A8C3I2E6 ^@ Similarity ^@ Belongs to the TPD52 family. http://togogenome.org/gene/8478:FTO ^@ http://purl.uniprot.org/uniprot/A0A8C3HDN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fto family.|||Cytoplasm|||Nucleus speckle http://togogenome.org/gene/8478:BNIP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FPC7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:ID2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P6N4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:ATP5PB ^@ http://purl.uniprot.org/uniprot/A0A8C3I9K2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ATPase B chain family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion|||Mitochondrion inner membrane http://togogenome.org/gene/8478:SWI5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMQ1 ^@ Function|||Similarity ^@ Belongs to the SWI5/SAE3 family.|||Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination. http://togogenome.org/gene/8478:BET1 ^@ http://purl.uniprot.org/uniprot/A0A8C3INP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:IMP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9K7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/8478:TMEM18 ^@ http://purl.uniprot.org/uniprot/A0A8C3ID21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM18 family.|||Membrane|||Nucleus membrane http://togogenome.org/gene/8478:HVCN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F767 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the hydrogen channel family.|||Homodimer.|||Membrane http://togogenome.org/gene/8478:LOC101936214 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.|||Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL.|||Secreted http://togogenome.org/gene/8478:GALNT11 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:DEF8 ^@ http://purl.uniprot.org/uniprot/A0A8C3HIY0 ^@ Similarity ^@ Belongs to the DEF8 family. http://togogenome.org/gene/8478:IGF2BP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3PC96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM IMP/VICKZ family.|||Cytoplasm http://togogenome.org/gene/8478:BPNT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZP5 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/8478:PPP4R2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FFM6|||http://purl.uniprot.org/uniprot/A0A8C3FH21 ^@ Similarity ^@ Belongs to the PPP4R2 family. http://togogenome.org/gene/8478:RAG2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RAG2 family.|||Nucleus http://togogenome.org/gene/8478:PTPRF ^@ http://purl.uniprot.org/uniprot/A0A8C3F6V0|||http://purl.uniprot.org/uniprot/A0A8C3F879|||http://purl.uniprot.org/uniprot/A0A8C3FBK6|||http://purl.uniprot.org/uniprot/A0A8C3FDJ1|||http://purl.uniprot.org/uniprot/A0A8C3FDN3|||http://purl.uniprot.org/uniprot/A0A8C3FDT6 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily. http://togogenome.org/gene/8478:GPD1L ^@ http://purl.uniprot.org/uniprot/A0A8C3ID12 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/8478:ENKUR ^@ http://purl.uniprot.org/uniprot/A0A8C3HPB3 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/8478:FKBP4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HAI3 ^@ Subcellular Location Annotation ^@ Mitochondrion|||cytoskeleton|||cytosol http://togogenome.org/gene/8478:SLC7A14 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRF7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:SENP5 ^@ http://purl.uniprot.org/uniprot/A0A8C3F8N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C48 family.|||nucleolus http://togogenome.org/gene/8478:IL18 ^@ http://purl.uniprot.org/uniprot/A0A8C3FW07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IL-1 family.|||Secreted http://togogenome.org/gene/8478:DNAJA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P7Z3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:MAP2K3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7M8|||http://purl.uniprot.org/uniprot/A0A8C3I8E8|||http://purl.uniprot.org/uniprot/A0A8C3I9R1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:RPL7 ^@ http://purl.uniprot.org/uniprot/A0A8C3FHB1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/8478:SS18L2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H5X6 ^@ Similarity ^@ Belongs to the SS18 family. http://togogenome.org/gene/8478:LOC101951468 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.|||Membrane|||Nucleus speckle|||filopodium|||lamellipodium http://togogenome.org/gene/8478:LOC101943325 ^@ http://purl.uniprot.org/uniprot/A0A8C3J002 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/8478:BZW2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAU8 ^@ Similarity ^@ Belongs to the BZW family. http://togogenome.org/gene/8478:VANGL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F556 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Vang family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:CDH8 ^@ http://purl.uniprot.org/uniprot/A0A8C3FSF7 ^@ Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell membrane http://togogenome.org/gene/8478:BRINP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HME9|||http://purl.uniprot.org/uniprot/A0A8C3P728 ^@ Similarity ^@ Belongs to the BRINP family. http://togogenome.org/gene/8478:LOC101947913 ^@ http://purl.uniprot.org/uniprot/A0A8C3HT67 ^@ Similarity ^@ Belongs to the RGS7BP/RGS9BP family. http://togogenome.org/gene/8478:TAAR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYD2 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:LIPG ^@ http://purl.uniprot.org/uniprot/A0A8C3IN12 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/8478:GET4 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8K5 ^@ Similarity ^@ Belongs to the GET4 family. http://togogenome.org/gene/8478:LOC101933522 ^@ http://purl.uniprot.org/uniprot/A0A8C3F267 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/8478:MAP3K13 ^@ http://purl.uniprot.org/uniprot/A0A8C3FIN0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. http://togogenome.org/gene/8478:ALG2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F512 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.|||Membrane http://togogenome.org/gene/8478:TBL1XR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PFI9 ^@ Similarity ^@ Belongs to the WD repeat EBI family. http://togogenome.org/gene/8478:ADCYAP1R1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FAP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:PAM16 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQJ0 ^@ Similarity ^@ Belongs to the TIM16/PAM16 family. http://togogenome.org/gene/8478:ABCC9 ^@ http://purl.uniprot.org/uniprot/A0A8C3FWV5 ^@ Subcellular Location Annotation|||Subunit ^@ Interacts with KCNJ11.|||Membrane http://togogenome.org/gene/8478:MNS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F9T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MNS1 family.|||Nucleus|||cilium axoneme|||flagellum axoneme http://togogenome.org/gene/8478:MAPKAP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IYF2|||http://purl.uniprot.org/uniprot/A0A8C3IYG9|||http://purl.uniprot.org/uniprot/A0A8C3J1B2 ^@ Similarity ^@ Belongs to the SIN1 family. http://togogenome.org/gene/8478:MGME1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGME1 family.|||Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair.|||Mitochondrion http://togogenome.org/gene/8478:ZDHHC3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHY5 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/8478:CAB39 ^@ http://purl.uniprot.org/uniprot/A0A8C3I200 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mo25 family.|||Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.|||Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity. http://togogenome.org/gene/8478:MPPED2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HC71 ^@ Similarity ^@ Belongs to the UPF0046 family. http://togogenome.org/gene/8478:IL2RG ^@ http://purl.uniprot.org/uniprot/A0A8C3HUR0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:MAT2B ^@ http://purl.uniprot.org/uniprot/A0A8C3FTB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.|||Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.|||Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. http://togogenome.org/gene/8478:EIF2A ^@ http://purl.uniprot.org/uniprot/A0A8C3HLY6 ^@ Function|||Similarity ^@ Belongs to the WD repeat EIF2A family.|||Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. http://togogenome.org/gene/8478:INKA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the INKA family.|||Nucleus http://togogenome.org/gene/8478:SLC25A45 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/8478:PSMB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FKR5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:KCNA10 ^@ http://purl.uniprot.org/uniprot/A0A8C3PE88 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:BAMBI ^@ http://purl.uniprot.org/uniprot/A0A8C3HR13 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BAMBI family.|||Membrane|||Negatively regulates TGF-beta signaling. http://togogenome.org/gene/8478:ANXA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P8P0 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family.|||Membrane|||basement membrane http://togogenome.org/gene/8478:RPRD1A ^@ http://purl.uniprot.org/uniprot/A0A8C3F602 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0400 (RTT103) family.|||Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.|||Nucleus http://togogenome.org/gene/8478:NOX1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HL07 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:GRAMD1A ^@ http://purl.uniprot.org/uniprot/A0A8C3FMK9 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:SLC24A2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I127|||http://purl.uniprot.org/uniprot/A0A8C3I2N1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.|||Membrane http://togogenome.org/gene/8478:NDUFB10 ^@ http://purl.uniprot.org/uniprot/A0A8C3I942 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.|||Belongs to the complex I NDUFB10 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:PCNX3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the pecanex family.|||Membrane http://togogenome.org/gene/8478:APLP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUI7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the APP family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:FBXO25 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAS4|||http://purl.uniprot.org/uniprot/A0A8C3IDY3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:HOXA4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/8478:MRPL22 ^@ http://purl.uniprot.org/uniprot/A0A8C3F355 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/8478:SNRPE ^@ http://purl.uniprot.org/uniprot/A0A8C3P8T1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/8478:ALDH2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FCR3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/8478:CNOT10 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CNOT10 family.|||Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:B3GALT6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IC09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:LOC101945909 ^@ http://purl.uniprot.org/uniprot/A0A8C3I992|||http://purl.uniprot.org/uniprot/A0A8C3PB37 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.|||Endoplasmic reticulum membrane|||Microsome membrane http://togogenome.org/gene/8478:SLC6A7 ^@ http://purl.uniprot.org/uniprot/A0A8C3FZ21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/8478:PTPRZ1 ^@ http://purl.uniprot.org/uniprot/A0A8C3H9H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.|||Membrane http://togogenome.org/gene/8478:GPCPD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IIK5 ^@ Similarity ^@ Belongs to the glycerophosphoryl diester phosphodiesterase family. http://togogenome.org/gene/8478:RARRES1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZQ2 ^@ Similarity ^@ Belongs to the protease inhibitor I47 (latexin) family. http://togogenome.org/gene/8478:GJA8 ^@ http://purl.uniprot.org/uniprot/A0A8C3FEY9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family. Alpha-type (group II) subfamily.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/8478:P2RX4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IR90 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the P2X receptor family.|||Functional P2XRs are organized as homomeric and heteromeric trimers.|||Membrane|||Receptor for ATP that acts as a ligand-gated ion channel. http://togogenome.org/gene/8478:LOC101944482 ^@ http://purl.uniprot.org/uniprot/A0A8C3H8N2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:CDR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I1Z9 ^@ Similarity ^@ Belongs to the CDR2 family. http://togogenome.org/gene/8478:LAMP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3H4Z2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMP family.|||Endosome membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Lysosome membrane|||Membrane http://togogenome.org/gene/8478:TENM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P7A6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tenascin family. Teneurin subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:IL13RA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HW08 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:NTMT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDW7 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/8478:LOC101953236 ^@ http://purl.uniprot.org/uniprot/A0A8C3HV25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:HYOU1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FA26 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/8478:DZIP1L ^@ http://purl.uniprot.org/uniprot/A0A8C3EYN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DZIP C2H2-type zinc-finger protein family.|||cilium basal body http://togogenome.org/gene/8478:SART1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNU66/SART1 family.|||Nucleus http://togogenome.org/gene/8478:ARL6IP4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IR35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ARL6IP4 family.|||Nucleus speckle|||nucleolus http://togogenome.org/gene/8478:GINS3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUN5|||http://purl.uniprot.org/uniprot/A0A8C3IWI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS3/PSF3 family.|||Chromosome|||Component of the GINS complex.|||Nucleus|||The GINS complex plays an essential role in the initiation of DNA replication. http://togogenome.org/gene/8478:POU1F1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IZB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/8478:CD34 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMI8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:IRX3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDQ4|||http://purl.uniprot.org/uniprot/A0A8C3HDT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/IRO homeobox family.|||Nucleus http://togogenome.org/gene/8478:NUDT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I6U2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Nudix hydrolase family.|||Monomer.|||Nucleus http://togogenome.org/gene/8478:MYMK ^@ http://purl.uniprot.org/uniprot/A0A8C3IAM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:RAB4A ^@ http://purl.uniprot.org/uniprot/A0A8C3FFT4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Protein transport. http://togogenome.org/gene/8478:CERCAM ^@ http://purl.uniprot.org/uniprot/A0A8C3IQ55 ^@ Similarity ^@ Belongs to the glycosyltransferase 25 family. http://togogenome.org/gene/8478:ISM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCV8 ^@ Similarity ^@ Belongs to the isthmin family. http://togogenome.org/gene/8478:CREG1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FED6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CREG family.|||Secreted http://togogenome.org/gene/8478:TUT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-B-like family.|||Nucleus speckle|||nucleolus http://togogenome.org/gene/8478:TINAGL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P9V0 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/8478:PPFIA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEQ4|||http://purl.uniprot.org/uniprot/A0A8C3P420 ^@ Similarity ^@ Belongs to the liprin family. Liprin-alpha subfamily. http://togogenome.org/gene/8478:JPH3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the junctophilin family.|||Cell membrane|||Endoplasmic reticulum membrane|||Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.|||Membrane http://togogenome.org/gene/8478:PDC ^@ http://purl.uniprot.org/uniprot/A0A8C3HMK1 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/8478:CEP43 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEW1|||http://purl.uniprot.org/uniprot/A0A8C3HEY6|||http://purl.uniprot.org/uniprot/A0A8C3HF31|||http://purl.uniprot.org/uniprot/A0A8C3HF55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CEP43 family.|||cilium basal body http://togogenome.org/gene/8478:ALG8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IWY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ALG6/ALG8 glucosyltransferase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:LOC101946150 ^@ http://purl.uniprot.org/uniprot/A0A8C3PG49 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/8478:TRMT6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRM6/GCD10 family.|||Heterotetramer.|||Nucleus|||Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. http://togogenome.org/gene/8478:ETFRF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FQF2 ^@ Similarity ^@ Belongs to the complex I LYR family. http://togogenome.org/gene/8478:PEX16 ^@ http://purl.uniprot.org/uniprot/A0A8C3P4C8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxin-16 family.|||Peroxisome membrane http://togogenome.org/gene/8478:NUP133 ^@ http://purl.uniprot.org/uniprot/A0A8C3FEK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleoporin Nup133 family.|||nuclear pore complex http://togogenome.org/gene/8478:TMCC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F3S8 ^@ Similarity ^@ Belongs to the TEX28 family. http://togogenome.org/gene/8478:LMX1B ^@ http://purl.uniprot.org/uniprot/A0A8C3IX61 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:RPS12 ^@ http://purl.uniprot.org/uniprot/A0A8C3P916 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS12 family. http://togogenome.org/gene/8478:ARPC5L ^@ http://purl.uniprot.org/uniprot/A0A8C3J0V9 ^@ Function|||Similarity ^@ Belongs to the ARPC5 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. http://togogenome.org/gene/8478:GASK1A ^@ http://purl.uniprot.org/uniprot/A0A8C3ID69|||http://purl.uniprot.org/uniprot/A0A8C3IG94 ^@ Similarity ^@ Belongs to the GASK family. http://togogenome.org/gene/8478:LOC101936497 ^@ http://purl.uniprot.org/uniprot/A0A8C3PDI3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:TLR5 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Toll-like receptor family.|||Membrane http://togogenome.org/gene/8478:SLC26A4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F160 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane|||Sodium-independent transporter of chloride and iodide. http://togogenome.org/gene/8478:CA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FQP7 ^@ Function|||Similarity ^@ Belongs to the alpha-carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/8478:GCSH ^@ http://purl.uniprot.org/uniprot/A0A8C3IJ30 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||Mitochondrion|||The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/8478:DLGAP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAU3 ^@ Similarity ^@ Belongs to the SAPAP family. http://togogenome.org/gene/8478:MED12L ^@ http://purl.uniprot.org/uniprot/A0A8C3I0C6|||http://purl.uniprot.org/uniprot/A0A8C3I0H2|||http://purl.uniprot.org/uniprot/A0A8C3P9R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 12 family.|||Nucleus http://togogenome.org/gene/8478:FMR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7I4|||http://purl.uniprot.org/uniprot/A0A8C3I854 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMR1 family.|||Cell membrane|||Cytoplasmic ribonucleoprotein granule|||Membrane|||Perikaryon|||Presynaptic cell membrane|||Stress granule|||Synaptic cell membrane|||axon|||centromere|||dendrite|||dendritic spine|||filopodium tip|||growth cone|||neuron projection|||nucleolus|||perinuclear region|||synaptosome http://togogenome.org/gene/8478:CHST13 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 2 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:AKAP12 ^@ http://purl.uniprot.org/uniprot/A0A8C3HT53|||http://purl.uniprot.org/uniprot/A0A8C3HT90 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:NDRG4 ^@ http://purl.uniprot.org/uniprot/A0A8C3ISL0|||http://purl.uniprot.org/uniprot/A0A8C3ITR0|||http://purl.uniprot.org/uniprot/A0A8C3IU56|||http://purl.uniprot.org/uniprot/A0A8C3PFF1 ^@ Similarity ^@ Belongs to the NDRG family. http://togogenome.org/gene/8478:ARF4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HE65 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/8478:PPP1R14C ^@ http://purl.uniprot.org/uniprot/A0A8C3HTE0 ^@ Similarity ^@ Belongs to the PP1 inhibitor family. http://togogenome.org/gene/8478:LOC101947716 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFR4 ^@ Similarity ^@ Belongs to the TMEM121 family. http://togogenome.org/gene/8478:DDX6 ^@ http://purl.uniprot.org/uniprot/A0A8C3H7G8 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/8478:DIABLO ^@ http://purl.uniprot.org/uniprot/A0A8C3IQV0 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/8478:TF ^@ http://purl.uniprot.org/uniprot/A0A8C3IBH2 ^@ Similarity ^@ Belongs to the transferrin family. http://togogenome.org/gene/8478:ATP6V0D2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HAQ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/8478:GCLC ^@ http://purl.uniprot.org/uniprot/A0A8C3IBD0 ^@ Similarity ^@ Belongs to the glutamate--cysteine ligase type 3 family. http://togogenome.org/gene/8478:MYB ^@ http://purl.uniprot.org/uniprot/A0A8C3HWK5|||http://purl.uniprot.org/uniprot/A0A8C3HWL5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:DLGAP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I064 ^@ Similarity ^@ Belongs to the SAPAP family. http://togogenome.org/gene/8478:TUBB3 ^@ http://purl.uniprot.org/uniprot/A0A8C3P665 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/8478:MOCOS ^@ http://purl.uniprot.org/uniprot/A0A8C3F6N1 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.|||Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. http://togogenome.org/gene/8478:LYPLAL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HG87 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 2 family. http://togogenome.org/gene/8478:RSL24D1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FAI9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/8478:THBD ^@ http://purl.uniprot.org/uniprot/A0A8C3IG48 ^@ Caution|||Function|||Subunit ^@ Interacts with ITGAL, ITGAM and ITGB2.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. http://togogenome.org/gene/8478:DPT ^@ http://purl.uniprot.org/uniprot/A0A8C3H6Q4 ^@ Similarity ^@ Belongs to the dermatopontin family. http://togogenome.org/gene/8478:BCL2L10 ^@ http://purl.uniprot.org/uniprot/A0A8C3IX63 ^@ Similarity ^@ Belongs to the Bcl-2 family. http://togogenome.org/gene/8478:EXOC5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IL76 ^@ Similarity ^@ Belongs to the SEC10 family. http://togogenome.org/gene/8478:CDK14 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9T5|||http://purl.uniprot.org/uniprot/A0A8C3ICZ7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:GPR37 ^@ http://purl.uniprot.org/uniprot/A0A8C3I755 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/8478:TSPO2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HW41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/8478:GNG4 ^@ http://purl.uniprot.org/uniprot/A0A8C3H719 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/8478:AMOT ^@ http://purl.uniprot.org/uniprot/A0A8C3HVG7 ^@ Similarity ^@ Belongs to the angiomotin family. http://togogenome.org/gene/8478:TAF9B ^@ http://purl.uniprot.org/uniprot/A0A8C3P6T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF9 family.|||Nucleus http://togogenome.org/gene/8478:EOMES ^@ http://purl.uniprot.org/uniprot/A0A8C3IGY6 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/8478:TMEM39A ^@ http://purl.uniprot.org/uniprot/A0A8C3F6T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM39 family.|||Membrane http://togogenome.org/gene/8478:CAMLG ^@ http://purl.uniprot.org/uniprot/A0A8C3FM67 ^@ Function|||Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells. http://togogenome.org/gene/8478:USP15 ^@ http://purl.uniprot.org/uniprot/A0A8C3F2J0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C19 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:MFN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEH4 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/8478:B3GNT9 ^@ http://purl.uniprot.org/uniprot/A0A8C3P309 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:ELOVL4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFC6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ELO family. ELOVL4 subfamily.|||Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Membrane|||Oligomer.|||The C-terminal di-lysine motif may confer endoplasmic reticulum localization. http://togogenome.org/gene/8478:GALNT9 ^@ http://purl.uniprot.org/uniprot/A0A8C3IKD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:SF3B5 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWA4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SF3B5 family.|||Component of the spliceosome B complex.|||Nucleus http://togogenome.org/gene/8478:COPS5 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M67A family. CSN5 subfamily.|||synaptic vesicle http://togogenome.org/gene/8478:LOC101938916 ^@ http://purl.uniprot.org/uniprot/A0A8C3F9M1 ^@ Similarity ^@ Belongs to the intercrine gamma family. http://togogenome.org/gene/8478:LONP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRJ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.|||Belongs to the peptidase S16 family.|||Peroxisome matrix http://togogenome.org/gene/8478:MAF ^@ http://purl.uniprot.org/uniprot/A0A8C3FQ89 ^@ Similarity ^@ Belongs to the bZIP family. Maf subfamily. http://togogenome.org/gene/8478:LMOD3 ^@ http://purl.uniprot.org/uniprot/A0A8C3EY48 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/8478:C20H9orf116 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7J3 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/8478:FOXL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I224 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:GAP43 ^@ http://purl.uniprot.org/uniprot/A0A8C3FB29 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the neuromodulin family.|||Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.|||Cell membrane|||Membrane|||Palmitoylated. Palmitoylation is essential for plasma membrane association.|||Synapse|||This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.|||filopodium membrane|||growth cone membrane http://togogenome.org/gene/8478:LOC101933963 ^@ http://purl.uniprot.org/uniprot/A0A8C3P744 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Caudal homeobox family.|||Nucleus http://togogenome.org/gene/8478:ELAVL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H9J9|||http://purl.uniprot.org/uniprot/A0A8C3H9K1 ^@ Similarity ^@ Belongs to the RRM elav family. http://togogenome.org/gene/8478:SURF4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF4 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:IRF8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHK1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:BTG2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVY4 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/8478:CDC25A ^@ http://purl.uniprot.org/uniprot/A0A8C3P7D2 ^@ Function|||Similarity ^@ Belongs to the MPI phosphatase family.|||Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. http://togogenome.org/gene/8478:GABRG2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FME8|||http://purl.uniprot.org/uniprot/A0A8C3FPE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/8478:STX7 ^@ http://purl.uniprot.org/uniprot/A0A8C3P921 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/8478:BICD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEZ0 ^@ Similarity ^@ Belongs to the BicD family. http://togogenome.org/gene/8478:LOC101935282 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZK4 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Component of the 40S small ribosomal subunit. http://togogenome.org/gene/8478:LIN7C ^@ http://purl.uniprot.org/uniprot/A0A8C3H691 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lin-7 family.|||Cell junction|||Cell membrane|||Membrane|||Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. http://togogenome.org/gene/8478:TTC27 ^@ http://purl.uniprot.org/uniprot/A0A8C3IM73 ^@ Similarity ^@ Belongs to the TTC27 family. http://togogenome.org/gene/8478:MRPL53 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJ03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL53 family.|||Mitochondrion http://togogenome.org/gene/8478:CIAO2B ^@ http://purl.uniprot.org/uniprot/A0A8C3P390 ^@ Similarity ^@ Belongs to the MIP18 family. http://togogenome.org/gene/8478:RBPMS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FEB9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:INSIG1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I027 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the INSIG family.|||Endoplasmic reticulum membrane|||Mediates feedback control of cholesterol synthesis.|||Membrane http://togogenome.org/gene/8478:RSPO3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZF6 ^@ Similarity ^@ Belongs to the R-spondin family. http://togogenome.org/gene/8478:ARL8B ^@ http://purl.uniprot.org/uniprot/A0A8C3HNM4 ^@ Subcellular Location Annotation ^@ Endosome membrane|||Late endosome membrane|||Lysosome membrane http://togogenome.org/gene/8478:STRA6 ^@ http://purl.uniprot.org/uniprot/A0A8C3FR70|||http://purl.uniprot.org/uniprot/A0A8C3FV67 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/8478:ST6GAL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJ51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/8478:L3MBTL3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYY3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:MDFIC ^@ http://purl.uniprot.org/uniprot/A0A8C3H941 ^@ Similarity ^@ Belongs to the MDFI family. http://togogenome.org/gene/8478:CRYGN ^@ http://purl.uniprot.org/uniprot/A0A8C3HYT3 ^@ Similarity|||Subunit ^@ Belongs to the beta/gamma-crystallin family.|||Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms. http://togogenome.org/gene/8478:KIF27 ^@ http://purl.uniprot.org/uniprot/A0A8C3INI6 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/8478:TMEM87A ^@ http://purl.uniprot.org/uniprot/A0A8C3FX05 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:PFKFB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H683 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphoglycerate mutase family. http://togogenome.org/gene/8478:CMTM6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:THRAP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I086 ^@ Similarity ^@ Belongs to the BCLAF1/THRAP3 family. http://togogenome.org/gene/8478:PTPN14 ^@ http://purl.uniprot.org/uniprot/A0A8C3HGZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.|||cytoskeleton http://togogenome.org/gene/8478:ST3GAL3 ^@ http://purl.uniprot.org/uniprot/A0A8C3F710|||http://purl.uniprot.org/uniprot/A0A8C3F721 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/8478:CMKLR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FGF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Belongs to the chemokine-like receptor (CMKLR) family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:TRMT2A ^@ http://purl.uniprot.org/uniprot/A0A8C3HUL6|||http://purl.uniprot.org/uniprot/A0A8C3HVJ2 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:CAT ^@ http://purl.uniprot.org/uniprot/A0A8C3HER0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the catalase family.|||Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.|||Peroxisome http://togogenome.org/gene/8478:FAM13B ^@ http://purl.uniprot.org/uniprot/A0A8C3FMW3|||http://purl.uniprot.org/uniprot/A0A8C3H9S0 ^@ Similarity ^@ Belongs to the FAM13 family. http://togogenome.org/gene/8478:PTP4A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEH2 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/8478:LAMB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3H5H0 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||basement membrane http://togogenome.org/gene/8478:DNM1L ^@ http://purl.uniprot.org/uniprot/A0A8C3I6K8 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. http://togogenome.org/gene/8478:DDIT3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family.|||Cytoplasm http://togogenome.org/gene/8478:CAPN7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHE1 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/8478:TMEM182 ^@ http://purl.uniprot.org/uniprot/A0A8C3FLQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM182 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:YIPF6 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:TLE1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I1Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat Groucho/TLE family.|||Nucleus http://togogenome.org/gene/8478:CCZ1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7G4 ^@ Similarity ^@ Belongs to the CCZ1 family. http://togogenome.org/gene/8478:LOC101941719 ^@ http://purl.uniprot.org/uniprot/A0A8C3P6V0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/8478:NPHS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IS74 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/8478:TBPL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P910 ^@ Similarity ^@ Belongs to the TBP family. http://togogenome.org/gene/8478:SLC10A7 ^@ http://purl.uniprot.org/uniprot/A0A8C3PFU1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.|||Cell membrane|||Does not show transport activity towards bile acids or steroid sulfates.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane http://togogenome.org/gene/8478:TRAPPC2L ^@ http://purl.uniprot.org/uniprot/A0A8C3IIN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPP small subunits family. Sedlin subfamily.|||perinuclear region http://togogenome.org/gene/8478:ACAD8 ^@ http://purl.uniprot.org/uniprot/A0A8C3HX69 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/8478:RAB19 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Membrane http://togogenome.org/gene/8478:MON1A ^@ http://purl.uniprot.org/uniprot/A0A8C3F4G7 ^@ Function|||Similarity ^@ Belongs to the MON1/SAND family.|||Plays an important role in membrane trafficking through the secretory apparatus. http://togogenome.org/gene/8478:DCBLD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FBT6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:BCAT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FP11|||http://purl.uniprot.org/uniprot/A0A8C3FQ24|||http://purl.uniprot.org/uniprot/A0A8C3FWJ5 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/8478:WNK1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IVY4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. http://togogenome.org/gene/8478:RNF13 ^@ http://purl.uniprot.org/uniprot/A0A8C3HL99 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:RC3H1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P709 ^@ Subcellular Location Annotation ^@ P-body http://togogenome.org/gene/8478:LOC101943319 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:DRAM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F4D4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:MAD1L1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PB10 ^@ Similarity ^@ Belongs to the MAD1 family. http://togogenome.org/gene/8478:MRPS33 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS33 family.|||Mitochondrion http://togogenome.org/gene/8478:SCG2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2M2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromogranin/secretogranin protein family.|||Secreted http://togogenome.org/gene/8478:CLDN18 ^@ http://purl.uniprot.org/uniprot/A0A8C3H5D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||tight junction http://togogenome.org/gene/8478:VAT1L ^@ http://purl.uniprot.org/uniprot/A0A8C3FRD4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/8478:PDHX ^@ http://purl.uniprot.org/uniprot/A0A8C3HF16 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/8478:NTNG2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I864 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:CACFD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calcium channel flower family.|||Membrane http://togogenome.org/gene/8478:ITM2A ^@ http://purl.uniprot.org/uniprot/A0A8C3HM10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ITM2 family.|||Membrane http://togogenome.org/gene/8478:RCL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC37 family.|||Cytoplasm http://togogenome.org/gene/8478:KLC4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F786|||http://purl.uniprot.org/uniprot/A0A8C3FAA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the kinesin light chain family.|||Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.|||Oligomeric complex composed of two heavy chains and two light chains.|||cytoskeleton http://togogenome.org/gene/8478:HPGD ^@ http://purl.uniprot.org/uniprot/A0A8C3IMS9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/8478:ARHGEF6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPL0 ^@ Subcellular Location Annotation ^@ lamellipodium http://togogenome.org/gene/8478:GJA5 ^@ http://purl.uniprot.org/uniprot/A0A8C3H848 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family. Alpha-type (group II) subfamily.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/8478:ORC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMZ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ORC1 family.|||Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.|||Nucleus|||ORC is composed of six subunits. http://togogenome.org/gene/8478:BCLAF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWJ3|||http://purl.uniprot.org/uniprot/A0A8C3HWJ8|||http://purl.uniprot.org/uniprot/A0A8C3HX25 ^@ Similarity ^@ Belongs to the BCLAF1/THRAP3 family. http://togogenome.org/gene/8478:HTR5A ^@ http://purl.uniprot.org/uniprot/A0A8C3HZ73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:POMGNT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 61 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:RER1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IA28 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RER1 family.|||Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.|||Membrane http://togogenome.org/gene/8478:TMEM43 ^@ http://purl.uniprot.org/uniprot/A0A8C3HM82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM43 family.|||Membrane http://togogenome.org/gene/8478:ZNF330 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOA36 family.|||nucleolus http://togogenome.org/gene/8478:SGCD ^@ http://purl.uniprot.org/uniprot/A0A8C3FAM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sarcoglycan beta/delta/gamma/zeta family.|||cytoskeleton|||sarcolemma http://togogenome.org/gene/8478:LRRC8A ^@ http://purl.uniprot.org/uniprot/A0A8C3III1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LRRC8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:NONO ^@ http://purl.uniprot.org/uniprot/A0A8C3HTN4 ^@ Subcellular Location Annotation ^@ Nucleus speckle http://togogenome.org/gene/8478:SOAT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:TES ^@ http://purl.uniprot.org/uniprot/A0A8C3FJ18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prickle / espinas / testin family.|||focal adhesion http://togogenome.org/gene/8478:TM2D3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FXU7|||http://purl.uniprot.org/uniprot/A0A8C3HBH8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:NDUFB6 ^@ http://purl.uniprot.org/uniprot/A0A8C3H9C2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB6 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:LOC122172113 ^@ http://purl.uniprot.org/uniprot/A0A8C3HX11 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family. http://togogenome.org/gene/8478:CELF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEB6|||http://purl.uniprot.org/uniprot/A0A8C3IEG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CELF/BRUNOL family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:POLH ^@ http://purl.uniprot.org/uniprot/A0A8C3INC0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:LOC101941978 ^@ http://purl.uniprot.org/uniprot/A0A8C3HY33 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/8478:LOC101952464 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8R0 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/8478:SPA17 ^@ http://purl.uniprot.org/uniprot/A0A8C3FX95 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates. http://togogenome.org/gene/8478:RRS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRS1 family.|||Involved in ribosomal large subunit assembly.|||Nucleus http://togogenome.org/gene/8478:SLC2A12 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWY6 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/8478:LOC101936113 ^@ http://purl.uniprot.org/uniprot/A0A8C3EYY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Early endosome|||Endosome|||Membrane http://togogenome.org/gene/8478:CYLD ^@ http://purl.uniprot.org/uniprot/A0A8C3P7V8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane|||centrosome|||cilium basal body|||perinuclear region|||spindle http://togogenome.org/gene/8478:NR2C2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLT8|||http://purl.uniprot.org/uniprot/A0A8C3HLW0|||http://purl.uniprot.org/uniprot/A0A8C3HLX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/8478:SIAH1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HSJ1 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/8478:PAMR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEV7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:PGK1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HV08 ^@ Similarity|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Monomer. http://togogenome.org/gene/8478:CWF19L2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZY7 ^@ Similarity ^@ Belongs to the CWF19 family. http://togogenome.org/gene/8478:LOC101951992 ^@ http://purl.uniprot.org/uniprot/A0A8C3EYF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/8478:TRAK1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFP4|||http://purl.uniprot.org/uniprot/A0A8C3PCW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the milton family.|||Early endosome|||Mitochondrion http://togogenome.org/gene/8478:LOC101935334 ^@ http://purl.uniprot.org/uniprot/A0A8C3FER5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:CMTR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IN82 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).|||S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. http://togogenome.org/gene/8478:RAB3GAP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3EY90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Rab3-GAP regulatory subunit family.|||Cytoplasm http://togogenome.org/gene/8478:SLC6A15 ^@ http://purl.uniprot.org/uniprot/A0A8C3H4P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.|||Membrane http://togogenome.org/gene/8478:LOC101950173 ^@ http://purl.uniprot.org/uniprot/A0A8C3H6V4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/8478:WLS ^@ http://purl.uniprot.org/uniprot/A0A8C3F2H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the wntless family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:EIF5A2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HS32 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-5A family.|||Endoplasmic reticulum membrane|||Membrane|||Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. http://togogenome.org/gene/8478:ZFPL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJF2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZFPL1 family.|||Membrane|||Required for cis-Golgi integrity and efficient ER to Golgi transport.|||The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.|||cis-Golgi network membrane http://togogenome.org/gene/8478:LGR4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F953 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:OPHN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FIM5 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Postsynapse|||Presynapse|||dendrite http://togogenome.org/gene/8478:ZDHHC15 ^@ http://purl.uniprot.org/uniprot/A0A8C3P759 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/8478:SLC17A5 ^@ http://purl.uniprot.org/uniprot/A0A8C3II23 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:TSPAN11 ^@ http://purl.uniprot.org/uniprot/A0A8C3FR64|||http://purl.uniprot.org/uniprot/A0A8C3FVZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/8478:LOC101938847 ^@ http://purl.uniprot.org/uniprot/A0A8C3H976 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/8478:DGKZ ^@ http://purl.uniprot.org/uniprot/A0A8C3HF58|||http://purl.uniprot.org/uniprot/A0A8C3HF63|||http://purl.uniprot.org/uniprot/A0A8C3HFA0|||http://purl.uniprot.org/uniprot/A0A8C3HFC1 ^@ Similarity ^@ Belongs to the eukaryotic diacylglycerol kinase family. http://togogenome.org/gene/8478:LOC101933606 ^@ http://purl.uniprot.org/uniprot/A0A8C3FCR1|||http://purl.uniprot.org/uniprot/A0A8C3H7N0 ^@ Similarity ^@ Belongs to the vinculin/alpha-catenin family. http://togogenome.org/gene/8478:AQP9 ^@ http://purl.uniprot.org/uniprot/A0A8C3FGU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/8478:CALCR ^@ http://purl.uniprot.org/uniprot/A0A8C3IKA5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 2 family.|||Cell membrane|||Interacts with GPRASP2.|||Membrane http://togogenome.org/gene/8478:PCSK7 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8U8 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/8478:PSAT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I1E3 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine. http://togogenome.org/gene/8478:SNX10 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sorting nexin family.|||Membrane http://togogenome.org/gene/8478:NKX2-2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJ09 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:NCOA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IC79|||http://purl.uniprot.org/uniprot/A0A8C3ICZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRC/p160 nuclear receptor coactivator family.|||Nucleus http://togogenome.org/gene/8478:RHO ^@ http://purl.uniprot.org/uniprot/A0A8C3P702 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Contains one covalently linked retinal chromophore.|||Membrane http://togogenome.org/gene/8478:RPL22 ^@ http://purl.uniprot.org/uniprot/A0A8C3I344 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/8478:AMFR ^@ http://purl.uniprot.org/uniprot/A0A8C3HD33|||http://purl.uniprot.org/uniprot/A0A8C3P2W4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:LOC101944735 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBY4 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/8478:CLIC5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IB03 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel CLIC family.|||Cytoplasm|||Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.|||Membrane http://togogenome.org/gene/8478:ARV1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FIL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARV1 family.|||Endoplasmic reticulum membrane|||Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.|||Membrane http://togogenome.org/gene/8478:MBD4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMT1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:LEPR ^@ http://purl.uniprot.org/uniprot/A0A8C3F1H0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type I cytokine receptor family. Type 2 subfamily.|||Membrane http://togogenome.org/gene/8478:GPR137 ^@ http://purl.uniprot.org/uniprot/A0A8C3IIQ0 ^@ Subcellular Location Annotation ^@ Lysosome membrane|||Membrane http://togogenome.org/gene/8478:KCNAB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2N2|||http://purl.uniprot.org/uniprot/A0A8C3I5E5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the shaker potassium channel beta subunit family.|||Cell membrane|||Membrane|||axon|||cytoskeleton|||synaptosome http://togogenome.org/gene/8478:XPO6 ^@ http://purl.uniprot.org/uniprot/A0A8C3ILB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:LOC101938274 ^@ http://purl.uniprot.org/uniprot/A0A8C3HAK7 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family. http://togogenome.org/gene/8478:CENPN ^@ http://purl.uniprot.org/uniprot/A0A8C3III5 ^@ Similarity ^@ Belongs to the CENP-N/CHL4 family. http://togogenome.org/gene/8478:JAKMIP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FK78 ^@ Similarity ^@ Belongs to the JAKMIP family. http://togogenome.org/gene/8478:TAFA4 ^@ http://purl.uniprot.org/uniprot/A0A8C3H4S1 ^@ Similarity ^@ Belongs to the TAFA family. http://togogenome.org/gene/8478:PDCL ^@ http://purl.uniprot.org/uniprot/A0A8C3HAX1 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/8478:PRKAR1B ^@ http://purl.uniprot.org/uniprot/A0A8C3I5V9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cAMP-dependent kinase regulatory chain family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:DENND5B ^@ http://purl.uniprot.org/uniprot/A0A8C3IXJ9 ^@ Caution|||Similarity ^@ Belongs to the RAB6IP1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:NUDT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H7Z6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/8478:CDH6 ^@ http://purl.uniprot.org/uniprot/A0A8C3F3K7 ^@ Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell membrane http://togogenome.org/gene/8478:DCTN4 ^@ http://purl.uniprot.org/uniprot/A0A8C3FSB8|||http://purl.uniprot.org/uniprot/A0A8C3FVL8|||http://purl.uniprot.org/uniprot/A0A8C3HB30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynactin subunit 4 family.|||cell cortex|||centrosome|||sarcomere|||stress fiber http://togogenome.org/gene/8478:BUD31 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BUD31 (G10) family.|||Nucleus http://togogenome.org/gene/8478:LOC101953571 ^@ http://purl.uniprot.org/uniprot/A0A8C3EX75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/8478:POMC ^@ http://purl.uniprot.org/uniprot/A0A8C3PC56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the POMC family.|||Endogenous opiate.|||Secreted|||Stimulates the adrenal glands to release cortisol. http://togogenome.org/gene/8478:SLC7A11 ^@ http://purl.uniprot.org/uniprot/A0A8C3IX65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:UBALD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCG2 ^@ Similarity ^@ Belongs to the UBALD family. http://togogenome.org/gene/8478:DPF3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FWR1 ^@ Similarity ^@ Belongs to the requiem/DPF family. http://togogenome.org/gene/8478:LOC101943025 ^@ http://purl.uniprot.org/uniprot/A0A8C3I144 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/8478:UBE4B ^@ http://purl.uniprot.org/uniprot/A0A8C3IBK5|||http://purl.uniprot.org/uniprot/A0A8C3IBM6|||http://purl.uniprot.org/uniprot/A0A8C3PC07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin conjugation factor E4 family.|||Cytoplasm http://togogenome.org/gene/8478:UBE2A ^@ http://purl.uniprot.org/uniprot/A0A8C3I938 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/8478:PSME3IP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IWD6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:TYRP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tyrosinase family.|||Melanosome membrane|||Membrane http://togogenome.org/gene/8478:TTC9 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEP0 ^@ Similarity ^@ Belongs to the TTC9 family. http://togogenome.org/gene/8478:SNTB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUB0 ^@ Subcellular Location Annotation ^@ Cell junction http://togogenome.org/gene/8478:UBE2L6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HU69 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/8478:ENDOG ^@ http://purl.uniprot.org/uniprot/A0A8C3IF86 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/8478:BCL2L14 ^@ http://purl.uniprot.org/uniprot/A0A8C3II88 ^@ Similarity ^@ Belongs to the Bcl-2 family. http://togogenome.org/gene/8478:PPIL4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTH9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.|||Nucleus|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/8478:TSEN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IRX2 ^@ Similarity ^@ Belongs to the tRNA-intron endonuclease family. http://togogenome.org/gene/8478:GTF3C5 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8J9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:EGFR ^@ http://purl.uniprot.org/uniprot/A0A8C3IL58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.|||Membrane http://togogenome.org/gene/8478:ERGIC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FRL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERGIC family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Golgi apparatus membrane|||Plays a role in transport between endoplasmic reticulum and Golgi. http://togogenome.org/gene/8478:LOC101936037 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8W5 ^@ Similarity ^@ Belongs to the vacuolar ATPase subunit S1 family. http://togogenome.org/gene/8478:RPS14 ^@ http://purl.uniprot.org/uniprot/A0A8C3FU65 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS11 family. http://togogenome.org/gene/8478:FAM199X ^@ http://purl.uniprot.org/uniprot/A0A8C3IA77 ^@ Similarity ^@ Belongs to the FAM199 family. http://togogenome.org/gene/8478:PEX5L ^@ http://purl.uniprot.org/uniprot/A0A8C3PFG1 ^@ Similarity ^@ Belongs to the peroxisomal targeting signal receptor family. http://togogenome.org/gene/8478:IRF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IRF family.|||Nucleus http://togogenome.org/gene/8478:XPOT ^@ http://purl.uniprot.org/uniprot/A0A8C3F5I0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Cytoplasm|||Nucleus|||tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. http://togogenome.org/gene/8478:ATP5F1A ^@ http://purl.uniprot.org/uniprot/A0A8C3IPC0 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/8478:TMEM242 ^@ http://purl.uniprot.org/uniprot/A0A8C3HSD9|||http://purl.uniprot.org/uniprot/A0A8C3HSF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM242 family.|||Membrane http://togogenome.org/gene/8478:SLC9A4 ^@ http://purl.uniprot.org/uniprot/A0A8C3H8T8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Apical cell membrane|||Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Interacts with CHP1 and CHP2.|||Membrane http://togogenome.org/gene/8478:THYN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P925 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. http://togogenome.org/gene/8478:DRD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FPG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:LZTFL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LZTFL1 family.|||Cytoplasm|||Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.|||Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking. http://togogenome.org/gene/8478:EPN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8X7 ^@ Similarity ^@ Belongs to the epsin family. http://togogenome.org/gene/8478:TELO2 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZ29 ^@ Similarity ^@ Belongs to the TEL2 family. http://togogenome.org/gene/8478:LFNG ^@ http://purl.uniprot.org/uniprot/A0A8C3I6Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:UNG ^@ http://purl.uniprot.org/uniprot/A0A8C3FHN5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.|||Mitochondrion|||Nucleus http://togogenome.org/gene/8478:CD74 ^@ http://purl.uniprot.org/uniprot/A0A8C3FS90 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:COLGALT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HQF8 ^@ Similarity ^@ Belongs to the glycosyltransferase 25 family. http://togogenome.org/gene/8478:PRTFDC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HPB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/8478:SLC39A10 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:PSMB7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IY53 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:OGFOD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P2X6 ^@ Similarity ^@ Belongs to the TPA1 family. http://togogenome.org/gene/8478:ATAD2B ^@ http://purl.uniprot.org/uniprot/A0A8C3I7M7 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/8478:METTL15 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCK9 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. RsmH family. http://togogenome.org/gene/8478:GDPD4 ^@ http://purl.uniprot.org/uniprot/A0A8C3J159 ^@ Similarity ^@ Belongs to the glycerophosphoryl diester phosphodiesterase family. http://togogenome.org/gene/8478:FARSB ^@ http://purl.uniprot.org/uniprot/A0A8C3I2C1 ^@ Similarity ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily. http://togogenome.org/gene/8478:KIF4A ^@ http://purl.uniprot.org/uniprot/A0A8C3HL35 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/8478:FAM167A ^@ http://purl.uniprot.org/uniprot/A0A8C3I835 ^@ Similarity ^@ Belongs to the FAM167 (SEC) family. http://togogenome.org/gene/8478:GRAMD1B ^@ http://purl.uniprot.org/uniprot/A0A8C3HNT2 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:CNIH2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/8478:TIMM10 ^@ http://purl.uniprot.org/uniprot/A0A8C3HV21 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/8478:ARL5B ^@ http://purl.uniprot.org/uniprot/A0A8C3HPT9 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/8478:GLRA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FW29 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Perikaryon|||Postsynaptic cell membrane|||Synapse|||Synaptic cell membrane|||dendrite http://togogenome.org/gene/8478:LSM14A ^@ http://purl.uniprot.org/uniprot/A0A8C3H5F2 ^@ Similarity ^@ Belongs to the LSM14 family. http://togogenome.org/gene/8478:ENO1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBL0|||http://purl.uniprot.org/uniprot/A0A8C3IDY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Cytoplasm http://togogenome.org/gene/8478:WNT3A ^@ http://purl.uniprot.org/uniprot/A0A8C3H624 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/8478:IARS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZK4 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/8478:TGFB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HGG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TGF-beta family.|||Homodimer; disulfide-linked.|||Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.|||extracellular matrix http://togogenome.org/gene/8478:MYF5 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZ00 ^@ Subcellular Location Annotation|||Subunit ^@ Efficient DNA binding requires dimerization with another bHLH protein.|||Nucleus http://togogenome.org/gene/8478:PRKCB ^@ http://purl.uniprot.org/uniprot/A0A8C3F4M5|||http://purl.uniprot.org/uniprot/A0A8C3H640 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.|||Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.|||Cytoplasm|||Membrane|||Nucleus http://togogenome.org/gene/8478:ABCB7 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:ASF1A ^@ http://purl.uniprot.org/uniprot/A0A8C3I0G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ASF1 family.|||Nucleus http://togogenome.org/gene/8478:ANAPC5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the APC5 family.|||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.|||spindle http://togogenome.org/gene/8478:HEBP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVC8 ^@ Similarity ^@ Belongs to the HEBP family. http://togogenome.org/gene/8478:LOC101937026 ^@ http://purl.uniprot.org/uniprot/A0A8C3I447|||http://purl.uniprot.org/uniprot/A0A8C3PAC7 ^@ Similarity ^@ Belongs to the AKAP110 family. http://togogenome.org/gene/8478:YARS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I5Z5 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/8478:TGM4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IG59 ^@ Cofactor|||Similarity ^@ Belongs to the transglutaminase superfamily. Transglutaminase family.|||Binds 1 Ca(2+) ion per subunit. http://togogenome.org/gene/8478:GALNS ^@ http://purl.uniprot.org/uniprot/A0A8C3IG75 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sulfatase family.|||Binds 1 Ca(2+) ion per subunit.|||Homodimer.|||Lysosome http://togogenome.org/gene/8478:NKX6-3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FCV9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:SLC25A38 ^@ http://purl.uniprot.org/uniprot/A0A8C3EYW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.|||Membrane|||Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:ITGB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVP9|||http://purl.uniprot.org/uniprot/A0A8C3HWX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin beta chain family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:PPP1R15B ^@ http://purl.uniprot.org/uniprot/A0A8C3HVN9 ^@ Similarity ^@ Belongs to the PPP1R15 family. http://togogenome.org/gene/8478:DAZAP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZS9 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus speckle|||nuclear body http://togogenome.org/gene/8478:TGFBR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F0T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Membrane http://togogenome.org/gene/8478:INSIG2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FTM6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the INSIG family.|||Endoplasmic reticulum membrane|||Mediates feedback control of cholesterol synthesis.|||Membrane http://togogenome.org/gene/8478:LOC101934340 ^@ http://purl.uniprot.org/uniprot/A0A8C3FR94 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:ADAM17 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKK2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:AK3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IR44 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK3 subfamily.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.|||Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.|||Mitochondrion matrix|||Monomer. http://togogenome.org/gene/8478:DTYMK ^@ http://purl.uniprot.org/uniprot/A0A8C3F417 ^@ Similarity ^@ Belongs to the thymidylate kinase family. http://togogenome.org/gene/8478:LOC101943565 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the calycin superfamily. Lipocalin family. Highly divergent.|||Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.|||Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.|||Secreted http://togogenome.org/gene/8478:LDAF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I1P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LDAF1 family.|||Endoplasmic reticulum membrane|||Lipid droplet|||Membrane http://togogenome.org/gene/8478:OS9 ^@ http://purl.uniprot.org/uniprot/A0A8C3HXX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the OS-9 family.|||Endoplasmic reticulum lumen|||Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation. http://togogenome.org/gene/8478:CMC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IKV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CMC family.|||Mitochondrion http://togogenome.org/gene/8478:OAF ^@ http://purl.uniprot.org/uniprot/A0A8C3FQL2 ^@ Similarity ^@ Belongs to the OAF family. http://togogenome.org/gene/8478:STMN4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFL7 ^@ Similarity ^@ Belongs to the stathmin family. http://togogenome.org/gene/8478:BABAM2 ^@ http://purl.uniprot.org/uniprot/A0A8C3ING2|||http://purl.uniprot.org/uniprot/A0A8C3PEE5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BABAM2 family.|||Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.|||Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.|||Cytoplasm|||May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.|||Nucleus http://togogenome.org/gene/8478:CCNE1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HSV3 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/8478:CDK18 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1K7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:LOC101939148 ^@ http://purl.uniprot.org/uniprot/A0A8C3HHS1 ^@ Similarity ^@ Belongs to the RPAP1 family. http://togogenome.org/gene/8478:NUDT21 ^@ http://purl.uniprot.org/uniprot/A0A8C3HD26 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Nudix hydrolase family. CPSF5 subfamily.|||Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.|||Cytoplasm|||Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.|||Nucleus http://togogenome.org/gene/8478:ZFPM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGT2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:SEC13 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SEC13 family.|||Lysosome membrane http://togogenome.org/gene/8478:MEX3C ^@ http://purl.uniprot.org/uniprot/A0A8C3INY8 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/8478:LOC101937540 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FIP1 family.|||Nucleus http://togogenome.org/gene/8478:PLCB3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IH66 ^@ Cofactor|||Function ^@ Binds 1 Ca(2+) ion per subunit.|||The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. http://togogenome.org/gene/8478:JUN ^@ http://purl.uniprot.org/uniprot/A0A8C3HL97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. Jun subfamily.|||Nucleus http://togogenome.org/gene/8478:DSTN ^@ http://purl.uniprot.org/uniprot/A0A8C3IGJ9 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. http://togogenome.org/gene/8478:KIF16B ^@ http://purl.uniprot.org/uniprot/A0A8C3IEX1|||http://purl.uniprot.org/uniprot/A0A8C3IFK0|||http://purl.uniprot.org/uniprot/A0A8C3IGF3|||http://purl.uniprot.org/uniprot/A0A8C3PCU5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/8478:HEXA ^@ http://purl.uniprot.org/uniprot/A0A8C3FFR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 20 family.|||Lysosome http://togogenome.org/gene/8478:TMEM151A ^@ http://purl.uniprot.org/uniprot/A0A8C3IF38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM151 family.|||Membrane http://togogenome.org/gene/8478:MGA ^@ http://purl.uniprot.org/uniprot/A0A8C3HHL4 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/8478:VAPA ^@ http://purl.uniprot.org/uniprot/A0A8C3J049 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:GNPAT ^@ http://purl.uniprot.org/uniprot/A0A8C3FPE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GPAT/DAPAT family.|||Peroxisome membrane http://togogenome.org/gene/8478:WDFY1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2G4 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/8478:TPM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HX60|||http://purl.uniprot.org/uniprot/A0A8C3HXC5|||http://purl.uniprot.org/uniprot/A0A8C3HZR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tropomyosin family.|||cytoskeleton http://togogenome.org/gene/8478:MRPL50 ^@ http://purl.uniprot.org/uniprot/A0A8C3FRD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL50 family.|||Mitochondrion http://togogenome.org/gene/8478:PBX1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HGY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/PBX homeobox family.|||Nucleus http://togogenome.org/gene/8478:ODR4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMK9 ^@ Function|||Similarity ^@ Belongs to the ODR-4 family.|||May play a role in the trafficking of a subset of G-protein coupled receptors. http://togogenome.org/gene/8478:FBLN7 ^@ http://purl.uniprot.org/uniprot/A0A8C3FCZ3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:TECPR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PAK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TECPR1 family.|||Lysosome membrane|||autophagosome membrane http://togogenome.org/gene/8478:PEX7 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat peroxin-7 family.|||Peroxisome matrix|||cytosol http://togogenome.org/gene/8478:GGA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F5W5|||http://purl.uniprot.org/uniprot/A0A8C3F958 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GGA protein family.|||Early endosome membrane|||Endosome membrane|||Membrane|||trans-Golgi network membrane http://togogenome.org/gene/8478:SLC8A3 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICP7|||http://purl.uniprot.org/uniprot/A0A8C3ICQ9|||http://purl.uniprot.org/uniprot/A0A8C3ICV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:LOC101943853 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZH2|||http://purl.uniprot.org/uniprot/A0A8C3I123 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the DNA photolyase class-1 family.|||Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.|||Binds 1 FAD per subunit.|||May have a photoreceptor function. http://togogenome.org/gene/8478:PPP1R9A ^@ http://purl.uniprot.org/uniprot/A0A8C3IKI1 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/8478:CXCR6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHG4 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:CTSB ^@ http://purl.uniprot.org/uniprot/A0A8C3I617 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/8478:IGFBP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUC7 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/8478:SLC41A3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLA2|||http://purl.uniprot.org/uniprot/A0A8C3HLC4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Membrane http://togogenome.org/gene/8478:SUSD4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEF0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:HSDL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HD70|||http://purl.uniprot.org/uniprot/A0A8C3HD84 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/8478:GNB5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IXY8 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/8478:NIBAN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HR11 ^@ Similarity ^@ Belongs to the Niban family. http://togogenome.org/gene/8478:SMARCA5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IWZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.|||Nucleus http://togogenome.org/gene/8478:TMED6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:BID ^@ http://purl.uniprot.org/uniprot/A0A8C3PGE3 ^@ Domain|||Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2.|||Induces caspases and apoptosis. Counters the protective effect of BCL2.|||Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/8478:DNAJC24 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCD5 ^@ Similarity ^@ Belongs to the DPH4 family. http://togogenome.org/gene/8478:TBX15 ^@ http://purl.uniprot.org/uniprot/A0A8C3H5D7 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/8478:PSMD9 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQZ4 ^@ Similarity ^@ Belongs to the proteasome subunit p27 family. http://togogenome.org/gene/8478:B2M ^@ http://purl.uniprot.org/uniprot/A0A8C3H834 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta-2-microglobulin family.|||Secreted http://togogenome.org/gene/8478:ATP1B3 ^@ http://purl.uniprot.org/uniprot/A0A8C3F5K8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the X(+)/potassium ATPases subunit beta family.|||Membrane|||This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. http://togogenome.org/gene/8478:CHD1L ^@ http://purl.uniprot.org/uniprot/A0A8C3F5Q5|||http://purl.uniprot.org/uniprot/A0A8C3FC41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family.|||Nucleus http://togogenome.org/gene/8478:IQSEC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I3L2 ^@ Similarity ^@ Belongs to the BRAG family. http://togogenome.org/gene/8478:GPC4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IP95 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glypican family.|||Cell membrane|||Cell surface proteoglycan. http://togogenome.org/gene/8478:LOC101934626 ^@ http://purl.uniprot.org/uniprot/A0A8C3HXH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:MRPL49 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL49 family.|||Mitochondrion http://togogenome.org/gene/8478:POLR2H ^@ http://purl.uniprot.org/uniprot/A0A8C3F3Q9 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RPB8 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/8478:SLC66A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IK81 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:SERPINI1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRU2 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/8478:PLCD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZG4|||http://purl.uniprot.org/uniprot/A0A8C3P9J7 ^@ Cofactor ^@ Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain. http://togogenome.org/gene/8478:HMBOX1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I4C4|||http://purl.uniprot.org/uniprot/A0A8C3I4W8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:LOC101945056 ^@ http://purl.uniprot.org/uniprot/A0A8C3F761 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/8478:BCO2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FPK6 ^@ Cofactor|||Similarity ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/8478:QTRT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F6A0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.|||Mitochondrion outer membrane|||Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). http://togogenome.org/gene/8478:MSX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJT9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:FAM189A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FVR7|||http://purl.uniprot.org/uniprot/A0A8C3G046 ^@ Similarity ^@ Belongs to the ENTREP family. http://togogenome.org/gene/8478:HSPB6 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZU5 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/8478:CAPN5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IWP2 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/8478:MED6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 6 family.|||Nucleus http://togogenome.org/gene/8478:UST ^@ http://purl.uniprot.org/uniprot/A0A8C3HVN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 3 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:GJC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F2H1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/8478:FAM168B ^@ http://purl.uniprot.org/uniprot/A0A8C3I2B6|||http://purl.uniprot.org/uniprot/A0A8C3I3L8 ^@ Similarity ^@ Belongs to the FAM168 family. http://togogenome.org/gene/8478:FOXL3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I736 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:CLPTM1L ^@ http://purl.uniprot.org/uniprot/A0A8C3HSH3|||http://purl.uniprot.org/uniprot/A0A8C3P7X7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CLPTM1 family.|||Membrane http://togogenome.org/gene/8478:TTC36 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8G8 ^@ Similarity ^@ Belongs to the TTC36 family. http://togogenome.org/gene/8478:NHSL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVB9|||http://purl.uniprot.org/uniprot/A0A8C3HVC1|||http://purl.uniprot.org/uniprot/A0A8C3HVF7|||http://purl.uniprot.org/uniprot/A0A8C3HVG2|||http://purl.uniprot.org/uniprot/A0A8C3HVK0|||http://purl.uniprot.org/uniprot/A0A8C3HVX1|||http://purl.uniprot.org/uniprot/A0A8C3HXR2 ^@ Similarity ^@ Belongs to the NHS family. http://togogenome.org/gene/8478:ZNF592 ^@ http://purl.uniprot.org/uniprot/A0A8C3FF26 ^@ Function|||Subcellular Location Annotation ^@ May be involved in transcriptional regulation.|||Nucleus http://togogenome.org/gene/8478:MPPED1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQ13 ^@ Similarity ^@ Belongs to the UPF0046 family. http://togogenome.org/gene/8478:RBM5 ^@ http://purl.uniprot.org/uniprot/A0A8C3F7P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RBM5/RBM10 family.|||Nucleus http://togogenome.org/gene/8478:ST6GALNAC6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQ95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/8478:RECQL ^@ http://purl.uniprot.org/uniprot/A0A8C3HAE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family. RecQ subfamily.|||Nucleus http://togogenome.org/gene/8478:SKIL ^@ http://purl.uniprot.org/uniprot/A0A8C3HRG7 ^@ Similarity ^@ Belongs to the SKI family. http://togogenome.org/gene/8478:SPRTN ^@ http://purl.uniprot.org/uniprot/A0A8C3FEJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Spartan family.|||Chromosome|||Nucleus http://togogenome.org/gene/8478:GRIA3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HFU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. http://togogenome.org/gene/8478:ISY1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ISY1 family.|||Nucleus http://togogenome.org/gene/8478:RFLNA ^@ http://purl.uniprot.org/uniprot/A0A8C3PEP7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Refilin family.|||Interacts with FLNA and FLNB.|||cytoskeleton http://togogenome.org/gene/8478:WNT9A ^@ http://purl.uniprot.org/uniprot/A0A8C3F1Z2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/8478:RAD52 ^@ http://purl.uniprot.org/uniprot/A0A8C3IVL6 ^@ Similarity ^@ Belongs to the RAD52 family. http://togogenome.org/gene/8478:LOC101949147 ^@ http://purl.uniprot.org/uniprot/A0A8C3FBT2 ^@ Similarity ^@ Belongs to the HMBS family. http://togogenome.org/gene/8478:STX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IKY1 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/8478:ST3GAL4 ^@ http://purl.uniprot.org/uniprot/A0A8C3FWC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/8478:KIF5B ^@ http://purl.uniprot.org/uniprot/A0A8C3HWV6 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/8478:PLXNA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLR9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the plexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:NUF2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMG3 ^@ Similarity ^@ Belongs to the NUF2 family. http://togogenome.org/gene/8478:TBCE ^@ http://purl.uniprot.org/uniprot/A0A8C3FD48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBCE family.|||Cytoplasm http://togogenome.org/gene/8478:LOC101942067 ^@ http://purl.uniprot.org/uniprot/A0A8C3F9T3|||http://purl.uniprot.org/uniprot/A0A8C3FBF8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Interacts with UHRF2/NIRF.|||May be involved in cell cycle regulation.|||Nucleus http://togogenome.org/gene/8478:TMEM229B ^@ http://purl.uniprot.org/uniprot/A0A8C3I9F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM229 family.|||Membrane http://togogenome.org/gene/8478:LOC101940544 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9K5 ^@ Similarity ^@ Belongs to the 'GDXG' lipolytic enzyme family. http://togogenome.org/gene/8478:LOC101935816 ^@ http://purl.uniprot.org/uniprot/A0A8C3IA91 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/8478:OLFM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7S8|||http://purl.uniprot.org/uniprot/A0A8C3I8J8 ^@ Subcellular Location Annotation ^@ Secreted|||Synapse http://togogenome.org/gene/8478:CLK1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P2D2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:KCNK1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FHD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Cell membrane|||Cytoplasmic vesicle|||Endosome|||Membrane|||Perikaryon|||Recycling endosome|||Synaptic cell membrane|||Vesicle|||dendrite http://togogenome.org/gene/8478:GGPS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FB95 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/8478:IGF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F176 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/8478:PPARG ^@ http://purl.uniprot.org/uniprot/A0A8C3IU34 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Cytoplasm|||Heterodimer with other nuclear receptors.|||Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.|||Nucleus http://togogenome.org/gene/8478:GNB4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUQ7 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/8478:VIPR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HV94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:LOC101948970 ^@ http://purl.uniprot.org/uniprot/A0A8C3IYA1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10A family.|||Binds 2 Zn(2+) ions per subunit.|||Can bind about 5 Ca(2+) ions per subunit. http://togogenome.org/gene/8478:ATP2C1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IE77 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.|||Catalyzes the hydrolysis of ATP coupled with the transport of calcium.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:MTFR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MTFR1 family.|||Mitochondrion|||Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission. http://togogenome.org/gene/8478:RIN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IH93 ^@ Similarity ^@ Belongs to the RIN (Ras interaction/interference) family. http://togogenome.org/gene/8478:MICOS10 ^@ http://purl.uniprot.org/uniprot/A0A8C3PD23 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MICOS complex subunit Mic10 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:TEKT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tektin family.|||flagellum http://togogenome.org/gene/8478:DUOXA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FF87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DUOXA family.|||Membrane http://togogenome.org/gene/8478:XKRX ^@ http://purl.uniprot.org/uniprot/A0A8C3HKY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XK family.|||Membrane http://togogenome.org/gene/8478:B3GNT4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IT75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:DLD ^@ http://purl.uniprot.org/uniprot/A0A8C3H514 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond.|||acrosome|||flagellum http://togogenome.org/gene/8478:PTPN11 ^@ http://purl.uniprot.org/uniprot/A0A8C3FG72|||http://purl.uniprot.org/uniprot/A0A8C3FHI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.|||Cytoplasm http://togogenome.org/gene/8478:HSPA8 ^@ http://purl.uniprot.org/uniprot/A0A8C3HN50 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/8478:PHF19 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Polycomblike family.|||Nucleus http://togogenome.org/gene/8478:PRKD3 ^@ http://purl.uniprot.org/uniprot/A0A8C3PD50 ^@ Activity Regulation|||Similarity|||Subcellular Location Annotation ^@ Activated by DAG and phorbol esters.|||Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.|||Cytoplasm|||Membrane http://togogenome.org/gene/8478:VOPP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IL52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VOPP1/ECOP family.|||Cytoplasmic vesicle membrane|||Endosome membrane|||Late endosome membrane|||Lysosome membrane|||Membrane http://togogenome.org/gene/8478:DUSP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FRM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.|||Nucleus http://togogenome.org/gene/8478:SLC37A4 ^@ http://purl.uniprot.org/uniprot/A0A8C3FAL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Membrane http://togogenome.org/gene/8478:CDIP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P2D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane http://togogenome.org/gene/8478:TMEM184C ^@ http://purl.uniprot.org/uniprot/A0A8C3IVD5|||http://purl.uniprot.org/uniprot/A0A8C3IY41 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:KIAA2013 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDH9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:LOC101948044 ^@ http://purl.uniprot.org/uniprot/A0A8C3H8C2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/8478:LOC101953652 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBV9 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/8478:SETD6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IWB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.|||Nucleus|||Protein-lysine N-methyltransferase. http://togogenome.org/gene/8478:TRADD ^@ http://purl.uniprot.org/uniprot/A0A8C3HD50 ^@ Subcellular Location Annotation ^@ Nucleus|||cytoskeleton http://togogenome.org/gene/8478:TSNAX ^@ http://purl.uniprot.org/uniprot/A0A8C3H822 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the translin family.|||Nucleus http://togogenome.org/gene/8478:THBS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P435 ^@ Caution|||Similarity ^@ Belongs to the thrombospondin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:SNAP25 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGQ0|||http://purl.uniprot.org/uniprot/A0A8C3PCW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP-25 family.|||Cell membrane|||Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.|||synaptosome http://togogenome.org/gene/8478:ATG3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FC34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG3 family.|||Cytoplasm http://togogenome.org/gene/8478:GK5 ^@ http://purl.uniprot.org/uniprot/A0A8C3FBB1 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/8478:HMOX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCG5 ^@ Similarity ^@ Belongs to the heme oxygenase family. http://togogenome.org/gene/8478:LOC101934335 ^@ http://purl.uniprot.org/uniprot/A0A8C3I0B4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the noggin family.|||Homodimer.|||Secreted http://togogenome.org/gene/8478:YEATS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PA14|||http://purl.uniprot.org/uniprot/A0A8C3PA17 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:MRPL37 ^@ http://purl.uniprot.org/uniprot/A0A8C3F8T5 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/8478:PPME1 ^@ http://purl.uniprot.org/uniprot/A0A8C3EYX9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the AB hydrolase superfamily.|||Binds PPP2CA and PPP2CB.|||Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme. http://togogenome.org/gene/8478:MAML1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FQL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mastermind family.|||Nucleus speckle http://togogenome.org/gene/8478:MIEF2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I817 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/8478:TMEM106B ^@ http://purl.uniprot.org/uniprot/A0A8C3IIE8 ^@ Similarity ^@ Belongs to the TMEM106 family. http://togogenome.org/gene/8478:NCDN ^@ http://purl.uniprot.org/uniprot/A0A8C3HZX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the neurochondrin family.|||Postsynapse http://togogenome.org/gene/8478:TNFRSF21 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAW9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:TCF7 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJ99|||http://purl.uniprot.org/uniprot/A0A8C3FJD0|||http://purl.uniprot.org/uniprot/A0A8C3FKG3|||http://purl.uniprot.org/uniprot/A0A8C3FRS0|||http://purl.uniprot.org/uniprot/A0A8C3H9F5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCF/LEF family.|||Nucleus http://togogenome.org/gene/8478:PATJ ^@ http://purl.uniprot.org/uniprot/A0A8C3HJP9 ^@ Subcellular Location Annotation ^@ tight junction http://togogenome.org/gene/8478:FABP6 ^@ http://purl.uniprot.org/uniprot/A0A8C3FL86 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/8478:DOLK ^@ http://purl.uniprot.org/uniprot/A0A8C3IF60 ^@ Similarity ^@ Belongs to the polyprenol kinase family. http://togogenome.org/gene/8478:NFKB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I856 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/8478:LAMP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HFZ5|||http://purl.uniprot.org/uniprot/A0A8C3P4Q9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMP family.|||Endosome membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Lysosome membrane|||Membrane http://togogenome.org/gene/8478:LOC101944606 ^@ http://purl.uniprot.org/uniprot/A0A8C3IYP8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:FLI1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/8478:TUBA8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IYZ8|||http://purl.uniprot.org/uniprot/A0A8C3PGH2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/8478:CMAS ^@ http://purl.uniprot.org/uniprot/A0A8C3FPB9 ^@ Similarity ^@ Belongs to the CMP-NeuNAc synthase family. http://togogenome.org/gene/8478:TXNL4B ^@ http://purl.uniprot.org/uniprot/A0A8C3FF77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DIM1 family.|||Nucleus|||Plays role in pre-mRNA splicing. http://togogenome.org/gene/8478:HHATL ^@ http://purl.uniprot.org/uniprot/A0A8C3FE26 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:RAB18 ^@ http://purl.uniprot.org/uniprot/A0A8C3HR16 ^@ Subcellular Location Annotation ^@ Apical cell membrane|||Cell membrane|||Lipid droplet http://togogenome.org/gene/8478:ETS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FWU2|||http://purl.uniprot.org/uniprot/A0A8C3FYL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:RPS6KA4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGF2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. http://togogenome.org/gene/8478:TNS3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUC3|||http://purl.uniprot.org/uniprot/A0A8C3P896|||http://purl.uniprot.org/uniprot/A0A8C3P8A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PTEN phosphatase protein family.|||focal adhesion http://togogenome.org/gene/8478:JAG1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCW2 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Putative Notch ligand involved in the mediation of Notch signaling. http://togogenome.org/gene/8478:URM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PE57 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.|||Belongs to the URM1 family.|||C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.|||Cytoplasm http://togogenome.org/gene/8478:LOC101938934 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PARI family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:LOC101941081 ^@ http://purl.uniprot.org/uniprot/A0A8C3J334 ^@ Similarity ^@ Belongs to the perilipin family. http://togogenome.org/gene/8478:HSD17B12 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEX7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/8478:LOC101935783 ^@ http://purl.uniprot.org/uniprot/A0A8C3I0R9 ^@ Similarity ^@ Belongs to the ARTD/PARP family. http://togogenome.org/gene/8478:MAGOH ^@ http://purl.uniprot.org/uniprot/A0A8C3EYM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mago nashi family.|||Nucleus http://togogenome.org/gene/8478:SLC39A13 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:TM7SF3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFT9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:MPC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FE76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/8478:ANAPC10 ^@ http://purl.uniprot.org/uniprot/A0A8C3IVZ4 ^@ Function|||Similarity ^@ Belongs to the APC10 family.|||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. http://togogenome.org/gene/8478:KCNK7 ^@ http://purl.uniprot.org/uniprot/A0A8C3II68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Cell membrane|||Cytoplasmic vesicle|||Endosome|||Membrane|||Perikaryon|||Recycling endosome|||Synaptic cell membrane|||Vesicle|||dendrite http://togogenome.org/gene/8478:LOC101941418 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:GPAT4 ^@ http://purl.uniprot.org/uniprot/A0A8C3H6M8 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/8478:SCG3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IW01|||http://purl.uniprot.org/uniprot/A0A8C3PG47 ^@ Subcellular Location Annotation ^@ Membrane|||Secreted|||secretory vesicle membrane http://togogenome.org/gene/8478:CHRDL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZ07 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/8478:TPPP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLV5 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/8478:LOC101953854 ^@ http://purl.uniprot.org/uniprot/A0A8C3FYW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Belongs to the chemokine-like receptor (CMKLR) family.|||Cell membrane|||Interacts with VGF-derived peptide TLQP-21.|||Membrane|||Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. http://togogenome.org/gene/8478:LOC101945370 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase VIIb family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/8478:SERPINH1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IVB8 ^@ Function|||Similarity ^@ Belongs to the serpin family.|||Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. http://togogenome.org/gene/8478:TMC7 ^@ http://purl.uniprot.org/uniprot/A0A8C3FYZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMC family.|||Membrane http://togogenome.org/gene/8478:RPL6 ^@ http://purl.uniprot.org/uniprot/A0A8C3FHH2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL6 family. http://togogenome.org/gene/8478:IWS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYJ0|||http://purl.uniprot.org/uniprot/A0A8C3P9E2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:LTV1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVE4 ^@ Similarity ^@ Belongs to the LTV1 family. http://togogenome.org/gene/8478:TULP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HAV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TUB family.|||Secreted http://togogenome.org/gene/8478:ZBED4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBE3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:PHAF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P2Y2 ^@ Similarity ^@ Belongs to the PHAF1 family. http://togogenome.org/gene/8478:PCYOX1L ^@ http://purl.uniprot.org/uniprot/A0A8C3FLF4 ^@ Similarity ^@ Belongs to the prenylcysteine oxidase family. http://togogenome.org/gene/8478:PHGDH ^@ http://purl.uniprot.org/uniprot/A0A8C3F8S9 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/8478:RBM48 ^@ http://purl.uniprot.org/uniprot/A0A8C3PDT9 ^@ Function|||Similarity ^@ As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.|||Belongs to the RBM48 family. http://togogenome.org/gene/8478:FOXB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVD4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:TBC1D23 ^@ http://purl.uniprot.org/uniprot/A0A8C3F8P5 ^@ Subcellular Location Annotation ^@ trans-Golgi network http://togogenome.org/gene/8478:MGST1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PGH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPEG family.|||Membrane http://togogenome.org/gene/8478:ZDHHC7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IH57 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/8478:TMEM178B ^@ http://purl.uniprot.org/uniprot/A0A8C3P2F9 ^@ Similarity ^@ Belongs to the TMEM178 family. http://togogenome.org/gene/8478:HAUS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HAUS1 family.|||spindle http://togogenome.org/gene/8478:IRX1 ^@ http://purl.uniprot.org/uniprot/A0A8C3EYH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/IRO homeobox family.|||Nucleus http://togogenome.org/gene/8478:ALOX5 ^@ http://purl.uniprot.org/uniprot/A0A8C3H828 ^@ Caution|||Cofactor|||Similarity ^@ Belongs to the lipoxygenase family.|||Binds 1 Fe cation per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:RAPSN ^@ http://purl.uniprot.org/uniprot/A0A8C3IEH3 ^@ Similarity ^@ Belongs to the RAPsyn family. http://togogenome.org/gene/8478:MFF ^@ http://purl.uniprot.org/uniprot/A0A8C3I355 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Tango11 family.|||Membrane|||Mitochondrion outer membrane|||Peroxisome|||Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. http://togogenome.org/gene/8478:RPL32 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMR6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/8478:TASP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGK6 ^@ Similarity ^@ Belongs to the Ntn-hydrolase family. http://togogenome.org/gene/8478:TXLNB ^@ http://purl.uniprot.org/uniprot/A0A8C3P8P8 ^@ Similarity ^@ Belongs to the taxilin family. http://togogenome.org/gene/8478:PKNOX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HBH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/MEIS homeobox family.|||Nucleus http://togogenome.org/gene/8478:PIGC ^@ http://purl.uniprot.org/uniprot/A0A8C3FBJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGC family.|||Membrane http://togogenome.org/gene/8478:FLCN ^@ http://purl.uniprot.org/uniprot/A0A8C3PB87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the folliculin family.|||Lysosome membrane|||Membrane|||Nucleus|||centrosome|||cilium|||cytosol|||spindle http://togogenome.org/gene/8478:KLHL40 ^@ http://purl.uniprot.org/uniprot/A0A8C3FAC3 ^@ Similarity|||Subcellular Location Annotation ^@ A band|||Belongs to the KLHL40 family.|||I band http://togogenome.org/gene/8478:LOC101948238 ^@ http://purl.uniprot.org/uniprot/A0A8C3HF44 ^@ Subcellular Location Annotation ^@ Cell membrane|||Early endosome|||Endosome|||Membrane http://togogenome.org/gene/8478:CTNNB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGE4 ^@ Similarity ^@ Belongs to the beta-catenin family. http://togogenome.org/gene/8478:SMYD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HGP6 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.|||cytosol http://togogenome.org/gene/8478:NAMPT ^@ http://purl.uniprot.org/uniprot/A0A8C3F7X7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAPRTase family.|||Cytoplasm|||Homodimer.|||Nucleus|||Secreted http://togogenome.org/gene/8478:SLC41A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F283 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Membrane http://togogenome.org/gene/8478:NADSYN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HL67|||http://purl.uniprot.org/uniprot/A0A8C3P6L1 ^@ Similarity|||Subunit ^@ Homohexamer.|||In the C-terminal section; belongs to the NAD synthetase family. http://togogenome.org/gene/8478:NFRKB ^@ http://purl.uniprot.org/uniprot/A0A8C3ITI5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:RAB33B ^@ http://purl.uniprot.org/uniprot/A0A8C3IWE2 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Rab family. http://togogenome.org/gene/8478:ZER1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGU4 ^@ Similarity ^@ Belongs to the zyg-11 family. http://togogenome.org/gene/8478:SFPQ ^@ http://purl.uniprot.org/uniprot/A0A8C3I052 ^@ Subcellular Location Annotation ^@ Nucleus speckle http://togogenome.org/gene/8478:GPC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I3W9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glypican family.|||Cell membrane|||Cell surface proteoglycan. http://togogenome.org/gene/8478:NKRF ^@ http://purl.uniprot.org/uniprot/A0A8C3I7N6 ^@ Similarity ^@ Belongs to the CARF family. http://togogenome.org/gene/8478:PSEN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HBL8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase A22A family.|||Cytoplasmic granule|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Homodimer.|||Membrane|||Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.|||Synapse|||The PAL motif is required for normal active site conformation.|||axon|||neuron projection http://togogenome.org/gene/8478:NSUN3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FDN7 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/8478:NFIB ^@ http://purl.uniprot.org/uniprot/A0A8C3INX3|||http://purl.uniprot.org/uniprot/A0A8C3IQP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CTF/NF-I family.|||Binds DNA as a homodimer.|||Nucleus|||Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. http://togogenome.org/gene/8478:KCNK4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/8478:DDX58 ^@ http://purl.uniprot.org/uniprot/A0A8C3FLU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family. RLR subfamily.|||Cytoplasm http://togogenome.org/gene/8478:SDE2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HD16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SDE2 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:CDH11 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCS9 ^@ Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell membrane http://togogenome.org/gene/8478:ATP2B4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HW09|||http://purl.uniprot.org/uniprot/A0A8C3HWE2|||http://purl.uniprot.org/uniprot/A0A8C3P8U2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.|||Catalyzes the hydrolysis of ATP coupled with the transport of calcium.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:EARS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F499 ^@ Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). http://togogenome.org/gene/8478:LOC101942851 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMT2 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/8478:RAB27B ^@ http://purl.uniprot.org/uniprot/A0A8C3INW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Endosome|||Late endosome|||Membrane http://togogenome.org/gene/8478:ATP6V1D ^@ http://purl.uniprot.org/uniprot/A0A8C3FG45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase D subunit family.|||clathrin-coated vesicle membrane http://togogenome.org/gene/8478:SNRPD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFX1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/8478:TRPM2 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZJ6|||http://purl.uniprot.org/uniprot/A0A8C3F1U4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:FGD4 ^@ http://purl.uniprot.org/uniprot/A0A8C3I5V1|||http://purl.uniprot.org/uniprot/A0A8C3I5X5|||http://purl.uniprot.org/uniprot/A0A8C3I6J9 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/8478:LOC101935285 ^@ http://purl.uniprot.org/uniprot/A0A8C3F2F6 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/8478:JAK1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F0V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.|||Endomembrane system http://togogenome.org/gene/8478:LOC101938767 ^@ http://purl.uniprot.org/uniprot/A0A8C3I199 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/8478:TYRO3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HHT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.|||Membrane http://togogenome.org/gene/8478:MTMR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I765|||http://purl.uniprot.org/uniprot/A0A8C3I7B6|||http://purl.uniprot.org/uniprot/A0A8C3I816|||http://purl.uniprot.org/uniprot/A0A8C3IAE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.|||Cytoplasm http://togogenome.org/gene/8478:RFC4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F0X3 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/8478:PROK2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FFI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AVIT (prokineticin) family.|||Secreted http://togogenome.org/gene/8478:CD82 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/8478:RAD18 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RAD18 family.|||Nucleus http://togogenome.org/gene/8478:CORO1C ^@ http://purl.uniprot.org/uniprot/A0A8C3FGP1 ^@ Similarity ^@ Belongs to the WD repeat coronin family. http://togogenome.org/gene/8478:LOC101950447 ^@ http://purl.uniprot.org/uniprot/A0A8C3FN32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Membrane http://togogenome.org/gene/8478:TLX3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBS9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:KDELR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2Z9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||COPI-coated vesicle membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:LOC101944630 ^@ http://purl.uniprot.org/uniprot/A0A8C3HM84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:LOC101951251 ^@ http://purl.uniprot.org/uniprot/A0A8C3ILK6 ^@ Similarity ^@ Belongs to the cytochrome c oxidase VIIa family. http://togogenome.org/gene/8478:PEX1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IL75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||cytosol http://togogenome.org/gene/8478:PRKCI ^@ http://purl.uniprot.org/uniprot/A0A8C3HRG0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. http://togogenome.org/gene/8478:HOATZ ^@ http://purl.uniprot.org/uniprot/A0A8C3FNZ2 ^@ Similarity ^@ Belongs to the HOATZ family. http://togogenome.org/gene/8478:PGM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKM5 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/8478:ING3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FTR3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/8478:CDCA8 ^@ http://purl.uniprot.org/uniprot/A0A8C3P9J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the borealin family.|||centromere http://togogenome.org/gene/8478:RDH10 ^@ http://purl.uniprot.org/uniprot/A0A8C3FH88 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/8478:LOC101947545 ^@ http://purl.uniprot.org/uniprot/A0A8C3HNX5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:OXTR ^@ http://purl.uniprot.org/uniprot/A0A8C3HN01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:LOC101952050 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBI7 ^@ Similarity ^@ Belongs to the TAF9 family. CENP-S/MHF1 subfamily. http://togogenome.org/gene/8478:PLD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HR81|||http://purl.uniprot.org/uniprot/A0A8C3HR99 ^@ Similarity ^@ Belongs to the phospholipase D family. http://togogenome.org/gene/8478:ATG13 ^@ http://purl.uniprot.org/uniprot/A0A8C3HF93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG13 family. Metazoan subfamily.|||Preautophagosomal structure http://togogenome.org/gene/8478:CAPN11 ^@ http://purl.uniprot.org/uniprot/A0A8C3ILS6 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/8478:RNF146 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZQ8 ^@ Domain|||Function|||PTM|||Subcellular Location Annotation ^@ E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.|||The WWE domain mediates non-covalent poly(ADP-ribose)-binding.|||Ubiquitinated; autoubiquitinated.|||cytosol http://togogenome.org/gene/8478:RPL7A ^@ http://purl.uniprot.org/uniprot/A0A8C3I8I4 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Component of the ribosome. http://togogenome.org/gene/8478:CDK9 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMG6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:WDR12 ^@ http://purl.uniprot.org/uniprot/A0A8C3FWV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat WDR12/YTM1 family.|||Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.|||Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.|||nucleolus|||nucleoplasm http://togogenome.org/gene/8478:YWHAQ ^@ http://purl.uniprot.org/uniprot/A0A8C3HKI7 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/8478:POPDC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F3Y0|||http://purl.uniprot.org/uniprot/A0A8C3F7C1 ^@ Similarity ^@ Belongs to the popeye family. http://togogenome.org/gene/8478:SLC35F4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPQ2|||http://purl.uniprot.org/uniprot/A0A8C3PDZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC35F solute transporter family.|||Membrane http://togogenome.org/gene/8478:STX19 ^@ http://purl.uniprot.org/uniprot/A0A8C3FDE8 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/8478:C3H6orf120 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0669 family.|||Secreted http://togogenome.org/gene/8478:NDUFV2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IZ42 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster.|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. http://togogenome.org/gene/8478:HMGN3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IF07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HMGN family.|||Nucleus http://togogenome.org/gene/8478:OTX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PDW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family. Bicoid subfamily.|||Nucleus http://togogenome.org/gene/8478:COG2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FIF9 ^@ Similarity ^@ Belongs to the COG2 family. http://togogenome.org/gene/8478:POLR1C ^@ http://purl.uniprot.org/uniprot/A0A8C3IMR9 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/8478:C1H11orf87 ^@ http://purl.uniprot.org/uniprot/A0A8C3I0E9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:PEX14 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxin-14 family.|||Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.|||Peroxisome membrane http://togogenome.org/gene/8478:CYRIA ^@ http://purl.uniprot.org/uniprot/A0A8C3HHD5|||http://purl.uniprot.org/uniprot/A0A8C3HHE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CYRI family.|||Membrane http://togogenome.org/gene/8478:ARPP19 ^@ http://purl.uniprot.org/uniprot/A0A8C3IY48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endosulfine family.|||Cytoplasm|||Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. http://togogenome.org/gene/8478:LOC101941898 ^@ http://purl.uniprot.org/uniprot/A0A8C3IKH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/8478:RAN ^@ http://purl.uniprot.org/uniprot/A0A8C3IK50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Ran family.|||GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.|||Nucleus http://togogenome.org/gene/8478:GABRB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IXQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/8478:ADCY1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P8B9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|||Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).|||Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.|||Membrane http://togogenome.org/gene/8478:LDHB ^@ http://purl.uniprot.org/uniprot/A0A8C3FUB3 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. LDH family. http://togogenome.org/gene/8478:CCNG1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FKT5 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/8478:PAX6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family.|||Nucleus http://togogenome.org/gene/8478:MDGA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3INS8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/8478:TFAP2E ^@ http://purl.uniprot.org/uniprot/A0A8C3I2N8 ^@ Similarity ^@ Belongs to the AP-2 family. http://togogenome.org/gene/8478:CRYBB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBN3 ^@ Similarity|||Subunit ^@ Belongs to the beta/gamma-crystallin family.|||Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms. http://togogenome.org/gene/8478:RBBP5 ^@ http://purl.uniprot.org/uniprot/A0A8C3F3N9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:KCNF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HK29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:AR ^@ http://purl.uniprot.org/uniprot/A0A8C3FI18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR3 subfamily.|||Nucleus http://togogenome.org/gene/8478:CMTM4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDB8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:TAF13 ^@ http://purl.uniprot.org/uniprot/A0A8C3FA20 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:SEC24A ^@ http://purl.uniprot.org/uniprot/A0A8C3FMM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC24 subfamily.|||COPII-coated vesicle membrane|||Endoplasmic reticulum membrane|||Membrane|||cytosol http://togogenome.org/gene/8478:LOC101950316 ^@ http://purl.uniprot.org/uniprot/A0A8C3I1G6 ^@ Similarity ^@ Belongs to the G-alpha family. G(q) subfamily. http://togogenome.org/gene/8478:C18H1orf174 ^@ http://purl.uniprot.org/uniprot/A0A8C3I4B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0688 family.|||Nucleus http://togogenome.org/gene/8478:PRR5L ^@ http://purl.uniprot.org/uniprot/A0A8C3HEW4 ^@ Similarity ^@ Belongs to the PROTOR family. http://togogenome.org/gene/8478:CRBN ^@ http://purl.uniprot.org/uniprot/A0A8C3HWR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRBN family.|||Nucleus http://togogenome.org/gene/8478:LOC101949762 ^@ http://purl.uniprot.org/uniprot/A0A8C3PE67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.|||Endoplasmic reticulum membrane|||Microsome membrane http://togogenome.org/gene/8478:ZDHHC4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F911 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/8478:DMRT3 ^@ http://purl.uniprot.org/uniprot/A0A8C3INC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DMRT family.|||Nucleus http://togogenome.org/gene/8478:LOC101940001 ^@ http://purl.uniprot.org/uniprot/A0A8C3IXB0 ^@ Similarity ^@ Belongs to the aldo/keto reductase family. http://togogenome.org/gene/8478:P4HA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPK9|||http://purl.uniprot.org/uniprot/A0A8C3IPV1|||http://purl.uniprot.org/uniprot/A0A8C3PE37 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P4HA family.|||Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.|||Endoplasmic reticulum lumen http://togogenome.org/gene/8478:PIK3C3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FHF4 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/8478:HTR6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGM9 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:OGFRL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HY70 ^@ Similarity ^@ Belongs to the opioid growth factor receptor family. http://togogenome.org/gene/8478:MDM4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1I8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MDM2/MDM4 family.|||Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.|||Nucleus http://togogenome.org/gene/8478:TSPO ^@ http://purl.uniprot.org/uniprot/A0A8C3IQ66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/8478:HDX ^@ http://purl.uniprot.org/uniprot/A0A8C3P6V9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:CAV1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJ24 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the caveolin family.|||Cell membrane|||Golgi apparatus membrane|||May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.|||Membrane|||caveola http://togogenome.org/gene/8478:RUNX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBQ5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:CEL ^@ http://purl.uniprot.org/uniprot/A0A8C3I8E9 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/8478:MGAT5 ^@ http://purl.uniprot.org/uniprot/A0A8C3FSQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 18 family.|||Golgi apparatus membrane|||Membrane|||Secreted http://togogenome.org/gene/8478:CCNY ^@ http://purl.uniprot.org/uniprot/A0A8C3P8L1 ^@ Similarity ^@ Belongs to the cyclin family. Cyclin Y subfamily. http://togogenome.org/gene/8478:COPG1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HL32|||http://purl.uniprot.org/uniprot/A0A8C3P6S9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COPG family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/8478:NRP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P8K4 ^@ Caution|||Similarity ^@ Belongs to the neuropilin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:DGAT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IXD9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:NCF2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HR46|||http://purl.uniprot.org/uniprot/A0A8C3HRD9 ^@ Similarity ^@ Belongs to the NCF2/NOXA1 family. http://togogenome.org/gene/8478:TENT5D ^@ http://purl.uniprot.org/uniprot/A0A8C3HM17 ^@ Similarity ^@ Belongs to the TENT family. http://togogenome.org/gene/8478:LOC101935140 ^@ http://purl.uniprot.org/uniprot/A0A8C3IV40 ^@ Subcellular Location Annotation ^@ acrosome http://togogenome.org/gene/8478:TAFA3 ^@ http://purl.uniprot.org/uniprot/A0A8C3P9K0 ^@ Similarity ^@ Belongs to the TAFA family. http://togogenome.org/gene/8478:MALL ^@ http://purl.uniprot.org/uniprot/A0A8C3IGJ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:CMC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CMC family.|||Mitochondrion http://togogenome.org/gene/8478:LOC101930758 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCT5 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/8478:APLP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F119|||http://purl.uniprot.org/uniprot/A0A8C3F3P5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the APP family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/8478:DHX9 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DEAH subfamily.|||Nucleus http://togogenome.org/gene/8478:CPSF3 ^@ http://purl.uniprot.org/uniprot/A0A8C3P6K8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:TANGO6 ^@ http://purl.uniprot.org/uniprot/A0A8C3PFJ4 ^@ Similarity ^@ Belongs to the Tango6 family. http://togogenome.org/gene/8478:WASL ^@ http://purl.uniprot.org/uniprot/A0A8C3I7Y6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:LOC101931260 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:CAV2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FN50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the caveolin family.|||Cell membrane|||Golgi apparatus membrane|||Membrane|||caveola http://togogenome.org/gene/8478:CSRNP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I1Z2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AXUD1 family.|||Nucleus http://togogenome.org/gene/8478:GUCY1A2 ^@ http://purl.uniprot.org/uniprot/A0A8C3EYT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|||Cytoplasm http://togogenome.org/gene/8478:MOGAT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IX23 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:ABCD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FU50 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:ACTR10 ^@ http://purl.uniprot.org/uniprot/A0A8C3INJ8 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/8478:PHF10 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SAYP family.|||Nucleus http://togogenome.org/gene/8478:PPIL3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCE2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/8478:DHCR7 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG4/ERG24 family.|||Membrane http://togogenome.org/gene/8478:IL5RA ^@ http://purl.uniprot.org/uniprot/A0A8C3P906 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:SEC24C ^@ http://purl.uniprot.org/uniprot/A0A8C3I7Q1|||http://purl.uniprot.org/uniprot/A0A8C3PB28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC24 subfamily.|||COPII-coated vesicle membrane|||Endoplasmic reticulum membrane|||Membrane|||cytosol http://togogenome.org/gene/8478:LOC101946450 ^@ http://purl.uniprot.org/uniprot/A0A8C3FUD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:LOC101937164 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRT3 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:LOC101943570 ^@ http://purl.uniprot.org/uniprot/A0A8C3IF33 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane|||The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.|||Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.|||extracellular space|||nucleoplasm|||sarcolemma http://togogenome.org/gene/8478:ADCY3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IC76 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|||Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).|||Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.|||Membrane http://togogenome.org/gene/8478:PKIA ^@ http://purl.uniprot.org/uniprot/A0A8C3FHT5 ^@ Function|||Similarity ^@ Belongs to the PKI family.|||Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. http://togogenome.org/gene/8478:TSPAN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HW47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/8478:LOC101941680 ^@ http://purl.uniprot.org/uniprot/A0A8C3IL48 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/8478:B3GNT5 ^@ http://purl.uniprot.org/uniprot/A0A8C3F0E9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:PSMD5 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDD8 ^@ Similarity ^@ Belongs to the proteasome subunit S5B/HSM3 family. http://togogenome.org/gene/8478:RTN3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGG6 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:FECH ^@ http://purl.uniprot.org/uniprot/A0A8C3IP34 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:ZDHHC13 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKN5 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Cytoplasmic vesicle membrane|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/8478:RAD50 ^@ http://purl.uniprot.org/uniprot/A0A8C3HT07 ^@ Similarity ^@ Belongs to the SMC family. RAD50 subfamily. http://togogenome.org/gene/8478:YIPF4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IKC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:GPR119 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDE5 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:MAP7 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWI3|||http://purl.uniprot.org/uniprot/A0A8C3HWM8 ^@ Similarity ^@ Belongs to the MAP7 family. http://togogenome.org/gene/8478:SCAI ^@ http://purl.uniprot.org/uniprot/A0A8C3IX07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SCAI family.|||Cytoplasm|||Interacts with DIAPH1. Forms a nuclear ternary complex with MRTFA and SRF.|||Nucleus|||Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. http://togogenome.org/gene/8478:RRP15 ^@ http://purl.uniprot.org/uniprot/A0A8C3P502 ^@ Similarity ^@ Belongs to the RRP15 family. http://togogenome.org/gene/8478:ECRG4 ^@ http://purl.uniprot.org/uniprot/A0A8C3FHS3 ^@ Similarity|||Subcellular Location Annotation ^@ Apical cell membrane|||Belongs to the augurin family.|||Cytoplasm|||Membrane|||Secreted http://togogenome.org/gene/8478:ZNF277 ^@ http://purl.uniprot.org/uniprot/A0A8C3IS55|||http://purl.uniprot.org/uniprot/A0A8C3IU38 ^@ Similarity ^@ Belongs to the ZNF277 family. http://togogenome.org/gene/8478:TRIP13 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1S0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family. PCH2 subfamily.|||Nucleus|||Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. http://togogenome.org/gene/8478:DDB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HPQ4|||http://purl.uniprot.org/uniprot/A0A8C3HPQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat DDB2/WDR76 family.|||Nucleus http://togogenome.org/gene/8478:MAB21L2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IZE4 ^@ Similarity ^@ Belongs to the mab-21 family. http://togogenome.org/gene/8478:PSD ^@ http://purl.uniprot.org/uniprot/A0A8C3I6W7 ^@ Subcellular Location Annotation ^@ ruffle membrane http://togogenome.org/gene/8478:LOC101950129 ^@ http://purl.uniprot.org/uniprot/A0A8C3ITK8|||http://purl.uniprot.org/uniprot/A0A8C3IW69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.|||Membrane http://togogenome.org/gene/8478:LOC101940914 ^@ http://purl.uniprot.org/uniprot/A0A8C3PDA5 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/8478:SEC31B ^@ http://purl.uniprot.org/uniprot/A0A8C3I6B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SEC31 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/8478:ARG1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZA9 ^@ Cofactor|||Similarity ^@ Belongs to the arginase family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/8478:MAN1A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P9Q1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 47 family. http://togogenome.org/gene/8478:AIF1L ^@ http://purl.uniprot.org/uniprot/A0A8C3IDH2 ^@ Subcellular Location Annotation ^@ ruffle membrane http://togogenome.org/gene/8478:PLA2G4F ^@ http://purl.uniprot.org/uniprot/A0A8C3HBN1 ^@ Domain|||Subcellular Location Annotation ^@ The N-terminal C2 domain associates with lipid membranes upon calcium binding.|||cytosol http://togogenome.org/gene/8478:LOC101940477 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8A1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:YIF1A ^@ http://purl.uniprot.org/uniprot/A0A8C3ICR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YIF1 family.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Has a role in transport between endoplasmic reticulum and Golgi.|||Membrane http://togogenome.org/gene/8478:LOC101933341 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7D5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HSF family.|||Nucleus http://togogenome.org/gene/8478:ATR ^@ http://purl.uniprot.org/uniprot/A0A8C3HA86 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. ATM subfamily. http://togogenome.org/gene/8478:SSBP3 ^@ http://purl.uniprot.org/uniprot/A0A8C3F8V3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:SH3YL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBH6 ^@ Similarity ^@ Belongs to the SH3YL1 family. http://togogenome.org/gene/8478:SNX8 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9U8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sorting nexin family.|||Membrane http://togogenome.org/gene/8478:MRPL14 ^@ http://purl.uniprot.org/uniprot/A0A8C3ILP7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/8478:ANXA6 ^@ http://purl.uniprot.org/uniprot/A0A8C3FUC1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family.|||May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.|||Melanosome http://togogenome.org/gene/8478:LOC101938931 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFS9 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:SLC13A4 ^@ http://purl.uniprot.org/uniprot/A0A8C3FXE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.|||Membrane http://togogenome.org/gene/8478:RELA ^@ http://purl.uniprot.org/uniprot/A0A8C3IFD7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:ATP1B4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HFY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the X(+)/potassium ATPases subunit beta family.|||Membrane|||This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. http://togogenome.org/gene/8478:FAM102A ^@ http://purl.uniprot.org/uniprot/A0A8C3IRA8 ^@ Similarity ^@ Belongs to the EEIG family. http://togogenome.org/gene/8478:FAM214A ^@ http://purl.uniprot.org/uniprot/A0A8C3IYK1|||http://purl.uniprot.org/uniprot/A0A8C3PGE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATOS family.|||Nucleus http://togogenome.org/gene/8478:LOC101952719 ^@ http://purl.uniprot.org/uniprot/A0A8C3EXY3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 33 family. http://togogenome.org/gene/8478:APH1B ^@ http://purl.uniprot.org/uniprot/A0A8C3HX53 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the APH-1 family.|||Component of the gamma-secretase complex.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors. http://togogenome.org/gene/8478:STXBP5L ^@ http://purl.uniprot.org/uniprot/A0A8C3F3F9|||http://purl.uniprot.org/uniprot/A0A8C3F3Z8|||http://purl.uniprot.org/uniprot/A0A8C3H5P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat L(2)GL family.|||Cell membrane|||Cytoplasm|||Membrane http://togogenome.org/gene/8478:TMEM151B ^@ http://purl.uniprot.org/uniprot/A0A8C3IN72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM151 family.|||Membrane http://togogenome.org/gene/8478:GDPD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P8E0 ^@ Similarity ^@ Belongs to the glycerophosphoryl diester phosphodiesterase family. http://togogenome.org/gene/8478:TOM1L2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8N9|||http://purl.uniprot.org/uniprot/A0A8C3IA12|||http://purl.uniprot.org/uniprot/A0A8C3IAY2|||http://purl.uniprot.org/uniprot/A0A8C3PB86 ^@ Similarity ^@ Belongs to the TOM1 family. http://togogenome.org/gene/8478:LOC101935126 ^@ http://purl.uniprot.org/uniprot/A0A8C3I3Q9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glypican family.|||Cell membrane|||Cell surface proteoglycan. http://togogenome.org/gene/8478:LOC101935599 ^@ http://purl.uniprot.org/uniprot/A0A8C3INY6 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/8478:BLOC1S2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7D0 ^@ Similarity ^@ Belongs to the BLOC1S2 family. http://togogenome.org/gene/8478:DGKB ^@ http://purl.uniprot.org/uniprot/A0A8C3IAM5|||http://purl.uniprot.org/uniprot/A0A8C3IBK2 ^@ Similarity ^@ Belongs to the eukaryotic diacylglycerol kinase family. http://togogenome.org/gene/8478:MOXD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYH0 ^@ Similarity ^@ Belongs to the copper type II ascorbate-dependent monooxygenase family. http://togogenome.org/gene/8478:CHRM4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HFA5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane|||The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. http://togogenome.org/gene/8478:ARL6IP5 ^@ http://purl.uniprot.org/uniprot/A0A8C3EY39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA1 family.|||Membrane http://togogenome.org/gene/8478:TIPRL ^@ http://purl.uniprot.org/uniprot/A0A8C3F814 ^@ Similarity ^@ Belongs to the TIP41 family. http://togogenome.org/gene/8478:GPR157 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 5 family.|||Membrane http://togogenome.org/gene/8478:MAP6 ^@ http://purl.uniprot.org/uniprot/A0A8C3PG33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STOP family.|||cytoskeleton http://togogenome.org/gene/8478:BANF2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IH37 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:PDIA6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HK08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein disulfide isomerase family.|||Endoplasmic reticulum lumen|||Melanosome http://togogenome.org/gene/8478:GATA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HL60 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:SSTR4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IH06 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:POLR2G ^@ http://purl.uniprot.org/uniprot/A0A8C3HXN7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.|||DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Nucleus http://togogenome.org/gene/8478:SOX14 ^@ http://purl.uniprot.org/uniprot/A0A8C3F6A2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:BRINP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLP8 ^@ Similarity ^@ Belongs to the BRINP family. http://togogenome.org/gene/8478:SEC16A ^@ http://purl.uniprot.org/uniprot/A0A8C3HDT4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SEC16 family.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.|||SEC16A and SEC16B are each present in multiple copies in a heteromeric complex. http://togogenome.org/gene/8478:LOC101941295 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.|||Cytoplasm http://togogenome.org/gene/8478:TRNT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HXC9 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/8478:MMP16 ^@ http://purl.uniprot.org/uniprot/A0A8C3FQE8|||http://purl.uniprot.org/uniprot/A0A8C3FV64|||http://purl.uniprot.org/uniprot/A0A8C3FXV4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10A family.|||Binds 2 Zn(2+) ions per subunit.|||Can bind about 5 Ca(2+) ions per subunit. http://togogenome.org/gene/8478:DLL4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HI54 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Putative Notch ligand involved in the mediation of Notch signaling. http://togogenome.org/gene/8478:TFIP11 ^@ http://purl.uniprot.org/uniprot/A0A8C3IA07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFP11/STIP family.|||Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.|||Nucleus http://togogenome.org/gene/8478:VWC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTK8 ^@ Subcellular Location Annotation ^@ Synapse http://togogenome.org/gene/8478:LOC103306399 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX16 family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/8478:BYSL ^@ http://purl.uniprot.org/uniprot/A0A8C3HX42 ^@ Similarity ^@ Belongs to the bystin family. http://togogenome.org/gene/8478:GPR31 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEW7 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:LOC101945157 ^@ http://purl.uniprot.org/uniprot/A0A8C3I5T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/8478:GRB10 ^@ http://purl.uniprot.org/uniprot/A0A8C3HSW8|||http://purl.uniprot.org/uniprot/A0A8C3HT06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GRB7/10/14 family.|||Cytoplasm http://togogenome.org/gene/8478:LOC101938983 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:ISCU ^@ http://purl.uniprot.org/uniprot/A0A8C3FGH6 ^@ Similarity ^@ Belongs to the NifU family. http://togogenome.org/gene/8478:CAPN6 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1R4 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/8478:SDHA ^@ http://purl.uniprot.org/uniprot/A0A8C3F0W2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/8478:METTL26 ^@ http://purl.uniprot.org/uniprot/A0A8C3IKQ9 ^@ Similarity ^@ Belongs to the UPF0585 family. http://togogenome.org/gene/8478:DTD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DTD family.|||Cytoplasm http://togogenome.org/gene/8478:TSPAN19 ^@ http://purl.uniprot.org/uniprot/A0A8C3F582 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/8478:STK38 ^@ http://purl.uniprot.org/uniprot/A0A8C3IRG0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:MYO1E ^@ http://purl.uniprot.org/uniprot/A0A8C3FV92 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/8478:SF3B1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF3B1 family.|||Nucleus http://togogenome.org/gene/8478:CDA ^@ http://purl.uniprot.org/uniprot/A0A8C3IKG4 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/8478:CPNE8 ^@ http://purl.uniprot.org/uniprot/A0A8C3HBZ5 ^@ Similarity ^@ Belongs to the copine family. http://togogenome.org/gene/8478:RNF8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQB6 ^@ Similarity ^@ Belongs to the CHFR family.|||Belongs to the RNF8 family. http://togogenome.org/gene/8478:LOC101949686 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICN9 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/8478:RPL24 ^@ http://purl.uniprot.org/uniprot/A0A8C3FA65 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/8478:KCNA4 ^@ http://purl.uniprot.org/uniprot/A0A8C3P241 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.|||Cell membrane|||Membrane|||axon http://togogenome.org/gene/8478:GAB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IW10|||http://purl.uniprot.org/uniprot/A0A8C3IWH8|||http://purl.uniprot.org/uniprot/A0A8C3J066 ^@ Similarity ^@ Belongs to the GAB family. http://togogenome.org/gene/8478:RAB14 ^@ http://purl.uniprot.org/uniprot/A0A8C3FSV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Early endosome membrane|||Endosome membrane|||Golgi apparatus membrane|||Recycling endosome|||phagosome|||trans-Golgi network membrane http://togogenome.org/gene/8478:RIOX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FFA7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ROX family. MINA53 subfamily.|||Binds 1 Fe(2+) ion per subunit.|||Nucleus|||Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. http://togogenome.org/gene/8478:GRM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTS5|||http://purl.uniprot.org/uniprot/A0A8C3HUF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:MRPS5 ^@ http://purl.uniprot.org/uniprot/A0A8C3P9D7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/8478:CCND1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCL4 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/8478:MYOZ1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I6H7 ^@ Similarity ^@ Belongs to the myozenin family. http://togogenome.org/gene/8478:CREBL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. ATF subfamily.|||Nucleus http://togogenome.org/gene/8478:OSBPL3 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICZ6|||http://purl.uniprot.org/uniprot/A0A8C3IFF7 ^@ Similarity ^@ Belongs to the OSBP family. http://togogenome.org/gene/8478:LOC101934137 ^@ http://purl.uniprot.org/uniprot/A0A8C3F8U7|||http://purl.uniprot.org/uniprot/A0A8C3H5X2 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/8478:SERPINE2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PA59 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/8478:CCN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P940 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CCN family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/8478:TIGD4 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEL1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:ERGIC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FYE4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERGIC family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays a role in transport between endoplasmic reticulum and Golgi. http://togogenome.org/gene/8478:PPP1CC ^@ http://purl.uniprot.org/uniprot/A0A8C3F8D3 ^@ Similarity ^@ Belongs to the PPP phosphatase family. PP-1 subfamily. http://togogenome.org/gene/8478:C15H16orf87 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTP3 ^@ Similarity ^@ Belongs to the UPF0547 family. http://togogenome.org/gene/8478:DHX30 ^@ http://purl.uniprot.org/uniprot/A0A8C3HPH1 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DEAH subfamily. http://togogenome.org/gene/8478:POU4F2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IWJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/8478:LOC101952652 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase CarF family.|||Membrane http://togogenome.org/gene/8478:HOXA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFB0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:STX5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IK63 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/8478:ZNF711 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLC9|||http://purl.uniprot.org/uniprot/A0A8C3HLF8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:USP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FK91 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/8478:ERC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IVN1|||http://purl.uniprot.org/uniprot/A0A8C3IY58|||http://purl.uniprot.org/uniprot/A0A8C3IYB0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:ZFP36L1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAD0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.|||Cytoplasm|||Nucleus|||Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs. http://togogenome.org/gene/8478:EVA1B ^@ http://purl.uniprot.org/uniprot/A0A8C3I2B7 ^@ Similarity ^@ Belongs to the EVA1 family. http://togogenome.org/gene/8478:GHSR ^@ http://purl.uniprot.org/uniprot/A0A8C3HRT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:POLA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHR5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.|||Belongs to the DNA polymerase alpha subunit B family.|||Nucleus http://togogenome.org/gene/8478:UXS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FHR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.|||Golgi stack membrane|||Membrane http://togogenome.org/gene/8478:SCRN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCB2 ^@ Similarity ^@ Belongs to the peptidase C69 family. Secernin subfamily. http://togogenome.org/gene/8478:DHRS7B ^@ http://purl.uniprot.org/uniprot/A0A8C3I7N5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/8478:HTR1F ^@ http://purl.uniprot.org/uniprot/A0A8C3FIJ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.|||Membrane http://togogenome.org/gene/8478:LANCL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IL63|||http://purl.uniprot.org/uniprot/A0A8C3ILC4 ^@ Similarity ^@ Belongs to the LanC-like protein family. http://togogenome.org/gene/8478:BORCS5 ^@ http://purl.uniprot.org/uniprot/A0A8C3F3J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS5 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/8478:FAM131C ^@ http://purl.uniprot.org/uniprot/A0A8C3FYG4 ^@ Similarity ^@ Belongs to the FAM131 family. http://togogenome.org/gene/8478:MAPK8IP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HF30|||http://purl.uniprot.org/uniprot/A0A8C3HFB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the JIP scaffold family.|||Cytoplasm http://togogenome.org/gene/8478:MVD ^@ http://purl.uniprot.org/uniprot/A0A8C3IH71 ^@ Function|||Similarity ^@ Belongs to the diphosphomevalonate decarboxylase family.|||Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis. http://togogenome.org/gene/8478:RBKS ^@ http://purl.uniprot.org/uniprot/A0A8C3IQU8 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/8478:A4GNT ^@ http://purl.uniprot.org/uniprot/A0A8C3EYX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 32 family.|||Golgi apparatus membrane http://togogenome.org/gene/8478:RCAN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDF4 ^@ Function|||Similarity ^@ Belongs to the RCAN family.|||Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. http://togogenome.org/gene/8478:LOC101938583 ^@ http://purl.uniprot.org/uniprot/A0A8C3FTP2|||http://purl.uniprot.org/uniprot/A0A8C3HAV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTR/RAG GTP-binding protein family.|||Cytoplasm|||Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.|||Lysosome http://togogenome.org/gene/8478:OLFML2A ^@ http://purl.uniprot.org/uniprot/A0A8C3IZ83 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:MNX1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I190 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:SHH ^@ http://purl.uniprot.org/uniprot/A0A8C3HZ65 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the hedgehog family.|||Cell membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane|||Multimer.|||The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.|||The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development. http://togogenome.org/gene/8478:CHM ^@ http://purl.uniprot.org/uniprot/A0A8C3HLW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rab GDI family.|||Cytoplasm|||Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. http://togogenome.org/gene/8478:DARS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMA2 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. http://togogenome.org/gene/8478:SNX30 ^@ http://purl.uniprot.org/uniprot/A0A8C3FQS8|||http://purl.uniprot.org/uniprot/A0A8C3FRM4 ^@ Similarity ^@ Belongs to the sorting nexin family. http://togogenome.org/gene/8478:SLC35D1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1T6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:INPP5D ^@ http://purl.uniprot.org/uniprot/A0A8C3IIG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.|||Membrane http://togogenome.org/gene/8478:LOC101946315 ^@ http://purl.uniprot.org/uniprot/A0A8C3FKZ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Cytoplasm|||Homotrimer.|||Nucleus http://togogenome.org/gene/8478:AIMP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I4E4 ^@ Subcellular Location Annotation ^@ Nucleus|||cytosol http://togogenome.org/gene/8478:HYAL4 ^@ http://purl.uniprot.org/uniprot/A0A8C3PB48 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 56 family. http://togogenome.org/gene/8478:AGAP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HXX6 ^@ Similarity ^@ Belongs to the centaurin gamma-like family. http://togogenome.org/gene/8478:LOC101938637 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJ08|||http://purl.uniprot.org/uniprot/A0A8C3PD06 ^@ Similarity ^@ Belongs to the BANP/SMAR1 family. http://togogenome.org/gene/8478:LOC101934897 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/8478:FABP7 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZX6 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/8478:GTPBP10 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9Q6 ^@ Similarity ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. http://togogenome.org/gene/8478:PTHLH ^@ http://purl.uniprot.org/uniprot/A0A8C3F0T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the parathyroid hormone family.|||Secreted http://togogenome.org/gene/8478:SAMM50 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SAM50/omp85 family.|||Mitochondrion outer membrane http://togogenome.org/gene/8478:LOC101931195 ^@ http://purl.uniprot.org/uniprot/A0A8C3F0K5 ^@ Similarity ^@ Belongs to the PICALM/SNAP91 family. http://togogenome.org/gene/8478:NAA30 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPP2 ^@ Similarity ^@ Belongs to the acetyltransferase family. MAK3 subfamily. http://togogenome.org/gene/8478:NUBP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCU3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.|||Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.|||Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.|||Cytoplasm|||Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. http://togogenome.org/gene/8478:IPO8 ^@ http://purl.uniprot.org/uniprot/A0A8C3PFN7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:SH3RF2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FLX7 ^@ Similarity ^@ Belongs to the SH3RF family. http://togogenome.org/gene/8478:TMEM63A ^@ http://purl.uniprot.org/uniprot/A0A8C3HD74|||http://purl.uniprot.org/uniprot/A0A8C3P2X3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSC1 (TC 1.A.17) family.|||Membrane http://togogenome.org/gene/8478:RPS3A ^@ http://purl.uniprot.org/uniprot/A0A8C3IQQ4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS1 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).|||Cytoplasm|||nucleolus http://togogenome.org/gene/8478:SLC14A2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the urea transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:MAP4K2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHF8 ^@ Function|||Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.|||May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. http://togogenome.org/gene/8478:PIGH ^@ http://purl.uniprot.org/uniprot/A0A8C3PBH1 ^@ Similarity ^@ Belongs to the PIGH family. http://togogenome.org/gene/8478:GNPTAB ^@ http://purl.uniprot.org/uniprot/A0A8C3H5B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the stealth family.|||Membrane http://togogenome.org/gene/8478:LOC101940259 ^@ http://purl.uniprot.org/uniprot/A0A8C3F9C3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMO family.|||Endoplasmic reticulum membrane|||Membrane|||Microsome membrane http://togogenome.org/gene/8478:CHST1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HFA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.|||Membrane http://togogenome.org/gene/8478:SMARCA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3INN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family.|||Nucleus http://togogenome.org/gene/8478:EIF2S1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FGI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-2-alpha family.|||Stress granule http://togogenome.org/gene/8478:MGRN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P2B2|||http://purl.uniprot.org/uniprot/A0A8C3P2C5 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||E3 ubiquitin ligase. http://togogenome.org/gene/8478:STIP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGK3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:CHST12 ^@ http://purl.uniprot.org/uniprot/A0A8C3I6Y8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 2 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:MAL ^@ http://purl.uniprot.org/uniprot/A0A8C3HYP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:MCM8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/8478:GINS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HWW6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS1/PSF1 family.|||Chromosome|||Component of the GINS complex.|||Nucleus|||Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. http://togogenome.org/gene/8478:OXSR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZF2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. http://togogenome.org/gene/8478:LOC101937751 ^@ http://purl.uniprot.org/uniprot/A0A8C3IK17 ^@ Similarity ^@ Belongs to the ARTD/PARP family. http://togogenome.org/gene/8478:TIMM9 ^@ http://purl.uniprot.org/uniprot/A0A8C3INZ3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/8478:ORAI1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Orai family.|||Membrane http://togogenome.org/gene/8478:SLC25A26 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/8478:INTS9 ^@ http://purl.uniprot.org/uniprot/A0A8C3I4X4|||http://purl.uniprot.org/uniprot/A0A8C3I759 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.|||Nucleus http://togogenome.org/gene/8478:GRPEL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJV4 ^@ Similarity ^@ Belongs to the GrpE family. http://togogenome.org/gene/8478:ADRB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Golgi apparatus|||Membrane http://togogenome.org/gene/8478:LOC101942324 ^@ http://purl.uniprot.org/uniprot/A0A8C3IH08 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/8478:AQP11 ^@ http://purl.uniprot.org/uniprot/A0A8C3IXQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.|||Membrane http://togogenome.org/gene/8478:SOX3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUH8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:STT3A ^@ http://purl.uniprot.org/uniprot/A0A8C3FYQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STT3 family.|||Membrane http://togogenome.org/gene/8478:PPIB ^@ http://purl.uniprot.org/uniprot/A0A8C3FEQ2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/8478:ASRGL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYA9 ^@ Similarity ^@ Belongs to the Ntn-hydrolase family. http://togogenome.org/gene/8478:CD109 ^@ http://purl.uniprot.org/uniprot/A0A8C3IHC7 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. http://togogenome.org/gene/8478:ALG12 ^@ http://purl.uniprot.org/uniprot/A0A8C3I931 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 22 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:RPE65 ^@ http://purl.uniprot.org/uniprot/A0A8C3F3Z4 ^@ Cofactor|||Similarity ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/8478:TMEM41A ^@ http://purl.uniprot.org/uniprot/A0A8C3FNV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM41 family.|||Membrane http://togogenome.org/gene/8478:TRMT1L ^@ http://purl.uniprot.org/uniprot/A0A8C3HQD9|||http://purl.uniprot.org/uniprot/A0A8C3P7P3 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.|||May play a role in motor coordination and exploratory behavior. http://togogenome.org/gene/8478:BLVRA ^@ http://purl.uniprot.org/uniprot/A0A8C3INV6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.|||Monomer.|||Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.|||cytosol http://togogenome.org/gene/8478:ASPHD2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAP7 ^@ Similarity ^@ Belongs to the aspartyl/asparaginyl beta-hydroxylase family. http://togogenome.org/gene/8478:AHR ^@ http://purl.uniprot.org/uniprot/A0A8C3IAV8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:MYSM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKR5 ^@ Similarity ^@ Belongs to the peptidase M67A family. MYSM1 subfamily. http://togogenome.org/gene/8478:DYNC1I1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IN49|||http://purl.uniprot.org/uniprot/A0A8C3PDL2 ^@ Similarity ^@ Belongs to the dynein intermediate chain family. http://togogenome.org/gene/8478:PHKB ^@ http://purl.uniprot.org/uniprot/A0A8C3HRM7|||http://purl.uniprot.org/uniprot/A0A8C3HRQ8|||http://purl.uniprot.org/uniprot/A0A8C3HSC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphorylase b kinase regulatory chain family.|||Cell membrane|||Membrane|||Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. http://togogenome.org/gene/8478:PSMA3 ^@ http://purl.uniprot.org/uniprot/A0A8C3INU4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/8478:LOC101946340 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJ21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HSF family.|||Nucleus http://togogenome.org/gene/8478:KCND3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8U4|||http://purl.uniprot.org/uniprot/A0A8C3IB13 ^@ Subcellular Location Annotation ^@ Membrane|||dendrite http://togogenome.org/gene/8478:UBA3 ^@ http://purl.uniprot.org/uniprot/A0A8C3EY20 ^@ Function|||Similarity ^@ Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.|||Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8. http://togogenome.org/gene/8478:HOOK1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the hook family.|||cytoskeleton http://togogenome.org/gene/8478:GALNT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FDP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:PER2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I248 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/8478:CASQ2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F9T8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the calsequestrin family.|||Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.|||Sarcoplasmic reticulum lumen http://togogenome.org/gene/8478:C7H18orf32 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEH0 ^@ Similarity ^@ Belongs to the UPF0729 family. http://togogenome.org/gene/8478:ESRRA ^@ http://purl.uniprot.org/uniprot/A0A8C3IJT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR3 subfamily.|||Nucleus http://togogenome.org/gene/8478:KCNH8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFQ7 ^@ Subcellular Location Annotation|||Subunit ^@ Membrane|||The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. http://togogenome.org/gene/8478:MND1 ^@ http://purl.uniprot.org/uniprot/A0A8C3INI2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MND1 family.|||Nucleus|||Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. http://togogenome.org/gene/8478:LOC101941138 ^@ http://purl.uniprot.org/uniprot/A0A8C3I718 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||Endosome membrane|||Late endosome membrane|||Lysosome membrane http://togogenome.org/gene/8478:LOC101950370 ^@ http://purl.uniprot.org/uniprot/A0A8C3IBH1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. http://togogenome.org/gene/8478:LOC101941762 ^@ http://purl.uniprot.org/uniprot/A0A8C3IG46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ClpA/ClpB family. Torsin subfamily.|||Endoplasmic reticulum lumen http://togogenome.org/gene/8478:EGFL7 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDW8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:LOC101953721 ^@ http://purl.uniprot.org/uniprot/A0A8C3HAD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calcitonin family.|||Secreted http://togogenome.org/gene/8478:NME5 ^@ http://purl.uniprot.org/uniprot/A0A8C3FVG4 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/8478:MAP3K9 ^@ http://purl.uniprot.org/uniprot/A0A8C3PC19 ^@ Activity Regulation|||Similarity|||Subunit ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.|||Homodimer.|||Homodimerization via the leucine zipper domains is required for autophosphorylation. http://togogenome.org/gene/8478:NMNAT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICE4 ^@ Similarity ^@ Belongs to the eukaryotic NMN adenylyltransferase family. http://togogenome.org/gene/8478:AP3B2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FEU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes large subunit family.|||Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.|||clathrin-coated vesicle membrane http://togogenome.org/gene/8478:PITPNM2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IP78|||http://purl.uniprot.org/uniprot/A0A8C3IQ94|||http://purl.uniprot.org/uniprot/A0A8C3IQA3 ^@ Similarity ^@ Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily. http://togogenome.org/gene/8478:IRX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IZ12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/IRO homeobox family.|||Nucleus http://togogenome.org/gene/8478:MMP15 ^@ http://purl.uniprot.org/uniprot/A0A8C3IWL6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10A family.|||Binds 2 Zn(2+) ions per subunit.|||Can bind about 5 Ca(2+) ions per subunit. http://togogenome.org/gene/8478:LOC101945045 ^@ http://purl.uniprot.org/uniprot/A0A8C3FPJ4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.|||Homodimer; disulfide-linked.|||Membrane http://togogenome.org/gene/8478:SEPTIN8 ^@ http://purl.uniprot.org/uniprot/A0A8C3HU31 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/8478:PIK3CB ^@ http://purl.uniprot.org/uniprot/A0A8C3I1V2 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/8478:EIF1B ^@ http://purl.uniprot.org/uniprot/A0A8C3F082 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/8478:HOXA7 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/8478:RPA3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IKC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the replication factor A protein 3 family.|||Nucleus http://togogenome.org/gene/8478:JAK2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.|||Endomembrane system|||Nucleus http://togogenome.org/gene/8478:GARS1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I324 ^@ Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Homodimer. http://togogenome.org/gene/8478:ALKAL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ALKAL family.|||Secreted http://togogenome.org/gene/8478:CPNE3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FRG8 ^@ Similarity ^@ Belongs to the copine family. http://togogenome.org/gene/8478:SRPRA ^@ http://purl.uniprot.org/uniprot/A0A8C3FWX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:B4GALT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F758 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Golgi apparatus membrane|||Membrane|||Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. http://togogenome.org/gene/8478:ITGB8 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZ68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin beta chain family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:STC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FKJ4 ^@ Similarity|||Subunit ^@ Belongs to the stanniocalcin family.|||Homodimer; disulfide-linked. http://togogenome.org/gene/8478:LOC103305696 ^@ http://purl.uniprot.org/uniprot/A0A8C3IEB1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/8478:SPSB4 ^@ http://purl.uniprot.org/uniprot/A0A8C3I297 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPSB family.|||Cytoplasm http://togogenome.org/gene/8478:SPICE1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F237 ^@ Subcellular Location Annotation ^@ centriole|||spindle http://togogenome.org/gene/8478:SDC1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PAK2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the syndecan proteoglycan family.|||Cell surface proteoglycan.|||Membrane http://togogenome.org/gene/8478:SSBP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FXX8 ^@ Subcellular Location Annotation ^@ mitochondrion nucleoid http://togogenome.org/gene/8478:TAF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HTK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF1 family.|||Nucleus http://togogenome.org/gene/8478:ARHGAP32 ^@ http://purl.uniprot.org/uniprot/A0A8C3IU19|||http://purl.uniprot.org/uniprot/A0A8C3IUP1|||http://purl.uniprot.org/uniprot/A0A8C3PFF7|||http://purl.uniprot.org/uniprot/A0A8C3PFJ7 ^@ Similarity ^@ Belongs to the PX domain-containing GAP family. http://togogenome.org/gene/8478:BRD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBI4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:DLX6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJN9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:RFTN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IB05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the raftlin family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:STK17A ^@ http://purl.uniprot.org/uniprot/A0A8C3IK99 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:PLA2G4A ^@ http://purl.uniprot.org/uniprot/A0A8C3HMG8 ^@ Domain ^@ The N-terminal C2 domain associates with lipid membranes upon calcium binding. http://togogenome.org/gene/8478:IP6K2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLC8 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/8478:SUCLG2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IUG3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.|||Binds 1 Mg(2+) ion per subunit.|||GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.|||Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.|||Mitochondrion http://togogenome.org/gene/8478:B3GAT3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I054 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:RIBC2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMT8|||http://purl.uniprot.org/uniprot/A0A8C3PDJ0 ^@ Similarity ^@ Belongs to the RIB43A family. http://togogenome.org/gene/8478:NKX2-5 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJ45 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:FGF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HVH5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Cytoplasm|||Nucleus|||Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.|||Secreted|||cell cortex|||cytosol http://togogenome.org/gene/8478:LOC101953726 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRP5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:USP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HJR0 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/8478:USP20 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C19 family. USP20/USP33 subfamily.|||centrosome|||perinuclear region http://togogenome.org/gene/8478:ERMP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:FAM20B ^@ http://purl.uniprot.org/uniprot/A0A8C3HM50 ^@ Similarity ^@ Belongs to the FAM20 family. http://togogenome.org/gene/8478:MED7 ^@ http://purl.uniprot.org/uniprot/A0A8C3F3J4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 7 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/8478:ADCY7 ^@ http://purl.uniprot.org/uniprot/A0A8C3HRD0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|||Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).|||Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.|||Membrane http://togogenome.org/gene/8478:TMEM123 ^@ http://purl.uniprot.org/uniprot/A0A8C3IWF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CD164 family.|||Membrane http://togogenome.org/gene/8478:RPS6KA6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLH3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. http://togogenome.org/gene/8478:GALNT14 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:ZDHHC21 ^@ http://purl.uniprot.org/uniprot/A0A8C3PED3 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/8478:TBCCD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3H4Y8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBCC family.|||centrosome|||spindle pole http://togogenome.org/gene/8478:ITM2C ^@ http://purl.uniprot.org/uniprot/A0A8C3PA31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ITM2 family.|||Membrane http://togogenome.org/gene/8478:PPARGC1B ^@ http://purl.uniprot.org/uniprot/A0A8C3FK12|||http://purl.uniprot.org/uniprot/A0A8C3FNL4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:SAR1B ^@ http://purl.uniprot.org/uniprot/A0A8C3FLT6 ^@ Similarity ^@ Belongs to the small GTPase superfamily. SAR1 family. http://togogenome.org/gene/8478:BZW1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCF7 ^@ Similarity ^@ Belongs to the BZW family. http://togogenome.org/gene/8478:AADAC ^@ http://purl.uniprot.org/uniprot/A0A8C3I0G9 ^@ Similarity ^@ Belongs to the 'GDXG' lipolytic enzyme family. http://togogenome.org/gene/8478:THNSL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HQ41 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/8478:SPTB ^@ http://purl.uniprot.org/uniprot/A0A8C3HUF8 ^@ Similarity ^@ Belongs to the spectrin family. http://togogenome.org/gene/8478:DACT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEQ5 ^@ Similarity ^@ Belongs to the dapper family. http://togogenome.org/gene/8478:CAPRIN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEW8 ^@ Similarity ^@ Belongs to the caprin family. http://togogenome.org/gene/8478:LOC101934214 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/8478:MAPK9 ^@ http://purl.uniprot.org/uniprot/A0A8C3FP52|||http://purl.uniprot.org/uniprot/A0A8C3FVQ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.|||Cytoplasm|||Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity. http://togogenome.org/gene/8478:LOC101937115 ^@ http://purl.uniprot.org/uniprot/A0A8C3IG51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:ATP2A2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PER6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.|||Catalyzes the hydrolysis of ATP coupled with the transport of calcium.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Sarcoplasmic reticulum membrane http://togogenome.org/gene/8478:UCK1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9J6 ^@ Similarity ^@ Belongs to the uridine kinase family. http://togogenome.org/gene/8478:MERTK ^@ http://purl.uniprot.org/uniprot/A0A8C3FDH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.|||Membrane http://togogenome.org/gene/8478:TNFRSF1B ^@ http://purl.uniprot.org/uniprot/A0A8C3IC16 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:ELF2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IV59|||http://purl.uniprot.org/uniprot/A0A8C3PFY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/8478:TAGLN3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FDU2 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/8478:SLC12A4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HDH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC12A transporter family.|||Membrane http://togogenome.org/gene/8478:GRHPR ^@ http://purl.uniprot.org/uniprot/A0A8C3FII6 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/8478:UGCG ^@ http://purl.uniprot.org/uniprot/A0A8C3FN51 ^@ Similarity ^@ Belongs to the glycosyltransferase 2 family. http://togogenome.org/gene/8478:DOCK8 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEB7 ^@ Similarity ^@ Belongs to the DOCK family. http://togogenome.org/gene/8478:LOC101931921 ^@ http://purl.uniprot.org/uniprot/A0A8C3FND1 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/8478:PPP2R5D ^@ http://purl.uniprot.org/uniprot/A0A8C3FF16 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B56 family. http://togogenome.org/gene/8478:ATP1B1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F8J0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the X(+)/potassium ATPases subunit beta family.|||Membrane|||This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. http://togogenome.org/gene/8478:FERMT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGX7 ^@ Similarity ^@ Belongs to the kindlin family. http://togogenome.org/gene/8478:PIH1D2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FPG3 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/8478:DPF2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IKE3 ^@ Similarity ^@ Belongs to the requiem/DPF family. http://togogenome.org/gene/8478:ABL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDJ4|||http://purl.uniprot.org/uniprot/A0A8C3PCD8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/8478:TSPAN13 ^@ http://purl.uniprot.org/uniprot/A0A8C3IB00 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:HSPA5 ^@ http://purl.uniprot.org/uniprot/A0A8C3J173 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heat shock protein 70 family.|||Endoplasmic reticulum lumen http://togogenome.org/gene/8478:ACO1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FKM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aconitase/IPM isomerase family.|||Cytoplasm http://togogenome.org/gene/8478:CASKIN1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F120 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/8478:MRPS9 ^@ http://purl.uniprot.org/uniprot/A0A8C3FLL0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/8478:IAH1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKJ3 ^@ Function|||Similarity ^@ Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.|||Probable lipase. http://togogenome.org/gene/8478:GNL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I256 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.|||GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.|||nucleolus http://togogenome.org/gene/8478:C9H3orf70 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJ86 ^@ Similarity ^@ Belongs to the UPF0524 family. http://togogenome.org/gene/8478:CBFB ^@ http://purl.uniprot.org/uniprot/A0A8C3HD30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CBF-beta family.|||Nucleus http://togogenome.org/gene/8478:NATD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7G0 ^@ Similarity ^@ Belongs to the NATD1 family. http://togogenome.org/gene/8478:BRAF ^@ http://purl.uniprot.org/uniprot/A0A8C3P2F7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. http://togogenome.org/gene/8478:EIF3B ^@ http://purl.uniprot.org/uniprot/A0A8C3PB23 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit B family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. http://togogenome.org/gene/8478:EIF2B1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQ83 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eIF-2B alpha/beta/delta subunits family.|||Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.|||Complex of five different subunits; alpha, beta, gamma, delta and epsilon. http://togogenome.org/gene/8478:CHCHD4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMR5 ^@ Subcellular Location Annotation ^@ Mitochondrion intermembrane space http://togogenome.org/gene/8478:ACTR3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FUG7 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/8478:LIPH ^@ http://purl.uniprot.org/uniprot/A0A8C3FQZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/8478:CRYAB ^@ http://purl.uniprot.org/uniprot/A0A8C3FQJ7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/8478:ZDHHC12 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGD4 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/8478:FERMT3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGK0 ^@ Similarity ^@ Belongs to the kindlin family. http://togogenome.org/gene/8478:NR2E3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FMB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR2 subfamily.|||Nucleus http://togogenome.org/gene/8478:PIN4 ^@ http://purl.uniprot.org/uniprot/A0A8C3HD29 ^@ Similarity ^@ Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily. http://togogenome.org/gene/8478:TMC5 ^@ http://purl.uniprot.org/uniprot/A0A8C3FVS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMC family.|||Membrane http://togogenome.org/gene/8478:ELK4 ^@ http://purl.uniprot.org/uniprot/A0A8C3F2K4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/8478:VPS8 ^@ http://purl.uniprot.org/uniprot/A0A8C3FNZ1 ^@ Similarity ^@ Belongs to the VPS8 family. http://togogenome.org/gene/8478:MMP7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IWK3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10A family.|||Binds 2 Zn(2+) ions per subunit.|||Can bind about 5 Ca(2+) ions per subunit. http://togogenome.org/gene/8478:MTHFD1L ^@ http://purl.uniprot.org/uniprot/A0A8C3HVC2 ^@ Similarity|||Subunit ^@ Homodimer.|||In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.|||In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family. http://togogenome.org/gene/8478:GLO1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IM23 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/8478:CAPZA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H955 ^@ Function|||Similarity|||Subunit ^@ Belongs to the F-actin-capping protein alpha subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit. http://togogenome.org/gene/8478:NDUFS3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUF2 ^@ Similarity ^@ Belongs to the complex I 30 kDa subunit family. http://togogenome.org/gene/8478:PARL ^@ http://purl.uniprot.org/uniprot/A0A8C3I213 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:AMZ1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I976 ^@ Function|||Similarity ^@ Belongs to the peptidase M54 family.|||Probable zinc metalloprotease. http://togogenome.org/gene/8478:RHPN2 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZ82 ^@ Similarity ^@ Belongs to the RHPN family. http://togogenome.org/gene/8478:LOXL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FNP9|||http://purl.uniprot.org/uniprot/A0A8C3FR35 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lysyl oxidase family.|||Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).|||The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.|||extracellular space http://togogenome.org/gene/8478:GRIA1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F635|||http://purl.uniprot.org/uniprot/A0A8C3H5Y5|||http://purl.uniprot.org/uniprot/A0A8C3H6E7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. http://togogenome.org/gene/8478:OCRL ^@ http://purl.uniprot.org/uniprot/A0A8C3HD24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.|||Early endosome membrane|||Endosome membrane|||Membrane|||phagosome membrane http://togogenome.org/gene/8478:TOMM5 ^@ http://purl.uniprot.org/uniprot/A0A8C3FIP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom5 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/8478:SF3B6 ^@ http://purl.uniprot.org/uniprot/A0A8C3I5H2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:GORASP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZE1 ^@ Similarity ^@ Belongs to the GORASP family. http://togogenome.org/gene/8478:C1H2orf49 ^@ http://purl.uniprot.org/uniprot/A0A8C3FN84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ashwin family.|||Nucleus http://togogenome.org/gene/8478:LOC101951429 ^@ http://purl.uniprot.org/uniprot/A0A8C3HQ32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cathelicidin family.|||Secreted http://togogenome.org/gene/8478:SYNJ2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HSD2 ^@ Similarity ^@ Belongs to the synaptojanin family.|||In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family. http://togogenome.org/gene/8478:CHFR ^@ http://purl.uniprot.org/uniprot/A0A8C3IY01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CHFR family.|||PML body http://togogenome.org/gene/8478:PSMB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3I0I8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:B4GALT4 ^@ http://purl.uniprot.org/uniprot/A0A8C3FA96 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Golgi apparatus membrane|||Membrane|||Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. http://togogenome.org/gene/8478:ADAMTS15 ^@ http://purl.uniprot.org/uniprot/A0A8C3IXJ8 ^@ Caution|||Cofactor|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/8478:PLOD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBY7 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/8478:SLC25A13 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJV7|||http://purl.uniprot.org/uniprot/A0A8C3IM60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/8478:LOC101939533 ^@ http://purl.uniprot.org/uniprot/A0A8C3J171 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPOT14 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:LOC101950687 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the somatostatin family.|||Secreted http://togogenome.org/gene/8478:TRAF6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TNF receptor-associated factor family. A subfamily.|||Lipid droplet|||Nucleus|||cell cortex http://togogenome.org/gene/8478:SATB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3ID43|||http://purl.uniprot.org/uniprot/A0A8C3ID74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/8478:PFKL ^@ http://purl.uniprot.org/uniprot/A0A8C3H5G4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homo- and heterotetramers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:MMAA ^@ http://purl.uniprot.org/uniprot/A0A8C3IWR4 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/8478:CRPPA ^@ http://purl.uniprot.org/uniprot/A0A8C3IE46 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Homodimer.|||cytosol http://togogenome.org/gene/8478:HEATR5B ^@ http://purl.uniprot.org/uniprot/A0A8C3IK07 ^@ Similarity ^@ Belongs to the HEATR5 family. http://togogenome.org/gene/8478:LOC101946790 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBI9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.|||Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.|||Membrane http://togogenome.org/gene/8478:FAM98A ^@ http://purl.uniprot.org/uniprot/A0A8C3IQ07 ^@ Similarity ^@ Belongs to the FAM98 family. http://togogenome.org/gene/8478:EIF1AD ^@ http://purl.uniprot.org/uniprot/A0A8C3IIR1 ^@ Similarity ^@ Belongs to the EIF1AD family. http://togogenome.org/gene/8478:CD247 ^@ http://purl.uniprot.org/uniprot/A0A8C3H8F7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CD3Z/FCER1G family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:CHEK1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FWK0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily. http://togogenome.org/gene/8478:PRPF38A ^@ http://purl.uniprot.org/uniprot/A0A8C3HMZ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRP38 family.|||Component of the spliceosome B complex.|||Involved in pre-mRNA splicing as a component of the spliceosome.|||Nucleus http://togogenome.org/gene/8478:UBE2I ^@ http://purl.uniprot.org/uniprot/A0A8C3F4X6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/8478:MSN ^@ http://purl.uniprot.org/uniprot/A0A8C3H924 ^@ Subcellular Location Annotation ^@ Membrane|||cytoskeleton http://togogenome.org/gene/8478:C4H11orf49 ^@ http://purl.uniprot.org/uniprot/A0A8C3HPN7|||http://purl.uniprot.org/uniprot/A0A8C3P7J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSTPP1 family.|||cytoskeleton http://togogenome.org/gene/8478:SLC25A43 ^@ http://purl.uniprot.org/uniprot/A0A8C3I7P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/8478:NDUFB8 ^@ http://purl.uniprot.org/uniprot/A0A8C3PAZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB8 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:PCSK5 ^@ http://purl.uniprot.org/uniprot/A0A8C3I3U0 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/8478:FGF13 ^@ http://purl.uniprot.org/uniprot/A0A8C3IRL6|||http://purl.uniprot.org/uniprot/A0A8C3IUJ5|||http://purl.uniprot.org/uniprot/A0A8C3PEX7 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/8478:FOXI1 ^@ http://purl.uniprot.org/uniprot/A0A8C3ILK3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:HMMR ^@ http://purl.uniprot.org/uniprot/A0A8C3FKZ4|||http://purl.uniprot.org/uniprot/A0A8C3FLN1 ^@ Subcellular Location Annotation ^@ spindle http://togogenome.org/gene/8478:AGRN ^@ http://purl.uniprot.org/uniprot/A0A8C3IEC6|||http://purl.uniprot.org/uniprot/A0A8C3IF58 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:MARK1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F3B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.|||dendrite http://togogenome.org/gene/8478:EFEMP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IIJ7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:UBE2E1 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICM8 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/8478:SMAD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3PFY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:PRDX5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IIT7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Peroxisome matrix|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. http://togogenome.org/gene/8478:LYRM1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I151 ^@ Similarity ^@ Belongs to the complex I LYR family. http://togogenome.org/gene/8478:MLF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZ27|||http://purl.uniprot.org/uniprot/A0A8C3HZ54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MLF family.|||Cytoplasm http://togogenome.org/gene/8478:ABCG4 ^@ http://purl.uniprot.org/uniprot/A0A8C3FJW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.|||Membrane http://togogenome.org/gene/8478:LOC101936633 ^@ http://purl.uniprot.org/uniprot/A0A8C3HB41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/8478:LOC101947030 ^@ http://purl.uniprot.org/uniprot/A0A8C3I0F6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the argonaute family. Ago subfamily.|||P-body|||Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. http://togogenome.org/gene/8478:LOC101950620 ^@ http://purl.uniprot.org/uniprot/A0A8C3P4A2 ^@ Caution|||Cofactor ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:BARHL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IAX8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:PRICKLE2 ^@ http://purl.uniprot.org/uniprot/A0A8C3ISA2|||http://purl.uniprot.org/uniprot/A0A8C3IUC2 ^@ Similarity ^@ Belongs to the prickle / espinas / testin family. http://togogenome.org/gene/8478:TFDP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H5X1|||http://purl.uniprot.org/uniprot/A0A8C3H6B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/8478:POLR3F ^@ http://purl.uniprot.org/uniprot/A0A8C3PD01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.|||Nucleus http://togogenome.org/gene/8478:DPAGT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FEG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family.|||Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:ARG2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FFW9 ^@ Cofactor|||Similarity ^@ Belongs to the arginase family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/8478:BMP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IG15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TGF-beta family.|||Secreted http://togogenome.org/gene/8478:WNT7A ^@ http://purl.uniprot.org/uniprot/A0A8C3PAE8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/8478:SSTR5 ^@ http://purl.uniprot.org/uniprot/A0A8C3I893 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/8478:RFX3 ^@ http://purl.uniprot.org/uniprot/A0A8C3INQ0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:LOC101948210 ^@ http://purl.uniprot.org/uniprot/A0A8C3HPW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SCAP family.|||COPII-coated vesicle membrane|||Golgi apparatus membrane http://togogenome.org/gene/8478:LLPH ^@ http://purl.uniprot.org/uniprot/A0A8C3INR8 ^@ Similarity ^@ Belongs to the learning-associated protein family. http://togogenome.org/gene/8478:LOC101952560 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FOXJ1 family.|||Nucleus http://togogenome.org/gene/8478:ATP10D ^@ http://purl.uniprot.org/uniprot/A0A8C3IX77|||http://purl.uniprot.org/uniprot/A0A8C3IXC2|||http://purl.uniprot.org/uniprot/A0A8C3J043 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/8478:LOC101950036 ^@ http://purl.uniprot.org/uniprot/A0A8C3HUL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UIF family.|||Nucleus speckle|||nucleoplasm http://togogenome.org/gene/8478:UBE2G2 ^@ http://purl.uniprot.org/uniprot/A0A8C3F149|||http://purl.uniprot.org/uniprot/A0A8C3F2I9|||http://purl.uniprot.org/uniprot/A0A8C3F7P2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/8478:BANF1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IGD8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:GSK3B ^@ http://purl.uniprot.org/uniprot/A0A8C3F8T8|||http://purl.uniprot.org/uniprot/A0A8C3FAY9|||http://purl.uniprot.org/uniprot/A0A8C3H6A4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. http://togogenome.org/gene/8478:C3H6orf58 ^@ http://purl.uniprot.org/uniprot/A0A8C3I150 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LEG1 family.|||Secreted http://togogenome.org/gene/8478:CA5A ^@ http://purl.uniprot.org/uniprot/A0A8C3IIX1 ^@ Function|||Similarity ^@ Belongs to the alpha-carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/8478:GPT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HSR2 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/8478:SNX5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJS8 ^@ Function|||Similarity ^@ Belongs to the sorting nexin family.|||Involved in several stages of intracellular trafficking. http://togogenome.org/gene/8478:SLC35B2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IRK9|||http://purl.uniprot.org/uniprot/A0A8C3PEC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.|||Membrane http://togogenome.org/gene/8478:PIK3CD ^@ http://purl.uniprot.org/uniprot/A0A8C3IDW9 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/8478:RANBP17 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9G2|||http://purl.uniprot.org/uniprot/A0A8C3PBE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:MCRIP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3EZ71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCRIP family.|||Nucleus|||Stress granule http://togogenome.org/gene/8478:B4GAT1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IE36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 49 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:PALM2AKAP2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FQQ0|||http://purl.uniprot.org/uniprot/A0A8C3FVH7 ^@ Similarity ^@ Belongs to the paralemmin family. http://togogenome.org/gene/8478:CELSR3 ^@ http://purl.uniprot.org/uniprot/A0A8C3P6R2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.|||Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Receptor that may have an important role in cell/cell signaling during nervous system formation. http://togogenome.org/gene/8478:CCDC39 ^@ http://purl.uniprot.org/uniprot/A0A8C3F0C7 ^@ Similarity ^@ Belongs to the CCDC39 family. http://togogenome.org/gene/8478:PODXL2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HLT4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:GALNT16 ^@ http://purl.uniprot.org/uniprot/A0A8C3I9Z6|||http://purl.uniprot.org/uniprot/A0A8C3PBN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:ATP6V0E1 ^@ http://purl.uniprot.org/uniprot/A0A8C3FRK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase e1/e2 subunit family.|||Membrane|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/8478:RAB27A ^@ http://purl.uniprot.org/uniprot/A0A8C3H7C1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Endosome|||Late endosome|||Membrane http://togogenome.org/gene/8478:ATP7A ^@ http://purl.uniprot.org/uniprot/A0A8C3HW06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Membrane|||trans-Golgi network membrane http://togogenome.org/gene/8478:PTGR2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HI52 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NADP-dependent oxidoreductase L4BD family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/8478:MYOZ3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FTE7 ^@ Similarity ^@ Belongs to the myozenin family. http://togogenome.org/gene/8478:CCK ^@ http://purl.uniprot.org/uniprot/A0A8C3IGM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gastrin/cholecystokinin family.|||Secreted http://togogenome.org/gene/8478:EHF ^@ http://purl.uniprot.org/uniprot/A0A8C3HET2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/8478:CUL5 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZT5 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/8478:ME2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PEK0 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/8478:APOOL ^@ http://purl.uniprot.org/uniprot/A0A8C3HLF2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.|||Mitochondrion inner membrane http://togogenome.org/gene/8478:FASLG ^@ http://purl.uniprot.org/uniprot/A0A8C3FH93 ^@ Similarity ^@ Belongs to the tumor necrosis factor family. http://togogenome.org/gene/8478:ST8SIA5 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQ03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/8478:YME1L1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P7T0 ^@ Similarity ^@ In the C-terminal section; belongs to the peptidase M41 family.|||In the N-terminal section; belongs to the AAA ATPase family. http://togogenome.org/gene/8478:VBP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F1R2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit alpha family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/8478:TIMM8B ^@ http://purl.uniprot.org/uniprot/A0A8C3FPF2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/8478:SRP9 ^@ http://purl.uniprot.org/uniprot/A0A8C3HD46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP9 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.|||Cytoplasm http://togogenome.org/gene/8478:OTUB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFQ2 ^@ Similarity ^@ Belongs to the peptidase C65 family. http://togogenome.org/gene/8478:SYT17 ^@ http://purl.uniprot.org/uniprot/A0A8C3FUQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptotagmin family.|||Membrane http://togogenome.org/gene/8478:PLEKHA8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IFF4 ^@ Subcellular Location Annotation ^@ trans-Golgi network membrane http://togogenome.org/gene/8478:MITF ^@ http://purl.uniprot.org/uniprot/A0A8C3EYX5|||http://purl.uniprot.org/uniprot/A0A8C3EZS6|||http://purl.uniprot.org/uniprot/A0A8C3F405|||http://purl.uniprot.org/uniprot/A0A8C3H4Z0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MiT/TFE family.|||Nucleus http://togogenome.org/gene/8478:ENPP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3P927 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/8478:BPGM ^@ http://purl.uniprot.org/uniprot/A0A8C3IYM3 ^@ Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. http://togogenome.org/gene/8478:ATP10B ^@ http://purl.uniprot.org/uniprot/A0A8C3FKL5|||http://purl.uniprot.org/uniprot/A0A8C3FLR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/8478:ADAMTS8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IW30 ^@ Caution|||Cofactor|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/8478:COG8 ^@ http://purl.uniprot.org/uniprot/A0A8C3IU88 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COG8 family.|||Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:LOC101949391 ^@ http://purl.uniprot.org/uniprot/A0A8C3FMG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBP family.|||Nucleus http://togogenome.org/gene/8478:LOC101950436 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCX7 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/8478:CAV3 ^@ http://purl.uniprot.org/uniprot/A0A8C3HN09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the caveolin family.|||Cell membrane|||Golgi apparatus membrane|||May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.|||Membrane|||caveola http://togogenome.org/gene/8478:KHDRBS2 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KHDRBS family.|||Cytoplasm http://togogenome.org/gene/8478:PPP6C ^@ http://purl.uniprot.org/uniprot/A0A8C3IYQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PPP phosphatase family.|||Cytoplasm http://togogenome.org/gene/8478:MTMR10 ^@ http://purl.uniprot.org/uniprot/A0A8C3FV05 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. http://togogenome.org/gene/8478:GATB ^@ http://purl.uniprot.org/uniprot/A0A8C3IQ38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Mitochondrion|||Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits. http://togogenome.org/gene/8478:LOC101947485 ^@ http://purl.uniprot.org/uniprot/A0A8C3PCA0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/8478:BOK ^@ http://purl.uniprot.org/uniprot/A0A8C3F4C0 ^@ Similarity ^@ Belongs to the Bcl-2 family. http://togogenome.org/gene/8478:CCDC126 ^@ http://purl.uniprot.org/uniprot/A0A8C3ICS1 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/8478:PPP1CB ^@ http://purl.uniprot.org/uniprot/A0A8C3EXU8 ^@ Similarity ^@ Belongs to the PPP phosphatase family. PP-1 subfamily. http://togogenome.org/gene/8478:LOC101938475 ^@ http://purl.uniprot.org/uniprot/A0A8C3ILZ9 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the paraoxonase family.|||Binds 2 calcium ions per subunit.|||Glycosylated. http://togogenome.org/gene/8478:LOC101948146 ^@ http://purl.uniprot.org/uniprot/A0A8C3IVL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IAP family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:RBP7 ^@ http://purl.uniprot.org/uniprot/A0A8C3IDU2 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/8478:CD47 ^@ http://purl.uniprot.org/uniprot/A0A8C3FAI5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/8478:DUOX2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FLP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Apical cell membrane|||Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.|||In the N-terminal section; belongs to the peroxidase family.|||Membrane http://togogenome.org/gene/8478:CUL3 ^@ http://purl.uniprot.org/uniprot/A0A8C3I2L4 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/8478:ESYT2 ^@ http://purl.uniprot.org/uniprot/A0A8C3P8N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the extended synaptotagmin family.|||Cell membrane|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/8478:ATP11B ^@ http://purl.uniprot.org/uniprot/A0A8C3EYH9|||http://purl.uniprot.org/uniprot/A0A8C3EYK1|||http://purl.uniprot.org/uniprot/A0A8C3F618 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/8478:MAFK ^@ http://purl.uniprot.org/uniprot/A0A8C3I8S0 ^@ Similarity ^@ Belongs to the bZIP family. Maf subfamily. http://togogenome.org/gene/8478:METTL1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HYA2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Forms a complex with WDR4.|||Nucleus http://togogenome.org/gene/8478:CLGN ^@ http://purl.uniprot.org/uniprot/A0A8C3IX11 ^@ Similarity ^@ Belongs to the calreticulin family. http://togogenome.org/gene/8478:TMEM59 ^@ http://purl.uniprot.org/uniprot/A0A8C3H6H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM59 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/8478:LOC101933092 ^@ http://purl.uniprot.org/uniprot/A0A8C3FLM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:NCOA2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FI73|||http://purl.uniprot.org/uniprot/A0A8C3FM87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRC/p160 nuclear receptor coactivator family.|||Nucleus http://togogenome.org/gene/8478:VMA21 ^@ http://purl.uniprot.org/uniprot/A0A8C3PB49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VMA21 family.|||COPII-coated vesicle membrane|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. http://togogenome.org/gene/8478:ADCK2 ^@ http://purl.uniprot.org/uniprot/A0A8C3HCR1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family. http://togogenome.org/gene/8478:AFG3L2 ^@ http://purl.uniprot.org/uniprot/A0A8C3J259 ^@ Similarity ^@ In the C-terminal section; belongs to the peptidase M41 family.|||In the N-terminal section; belongs to the AAA ATPase family. http://togogenome.org/gene/8478:LOC101938251 ^@ http://purl.uniprot.org/uniprot/A0A8C3J168 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/8478:ZEB1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HR48|||http://purl.uniprot.org/uniprot/A0A8C3P7U8 ^@ Similarity ^@ Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family. http://togogenome.org/gene/8478:NOL6 ^@ http://purl.uniprot.org/uniprot/A0A8C3FF32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NRAP family.|||Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.|||nucleolus http://togogenome.org/gene/8478:LOC101953642 ^@ http://purl.uniprot.org/uniprot/A0A8C3HEU9 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/8478:KDM4C ^@ http://purl.uniprot.org/uniprot/A0A8C3IQV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the JHDM3 histone demethylase family.|||Nucleus http://togogenome.org/gene/8478:ALDH9A1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMF2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/8478:SFRP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3F8P1 ^@ Caution|||Similarity ^@ Belongs to the secreted frizzled-related protein (sFRP) family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:PIM3 ^@ http://purl.uniprot.org/uniprot/A0A8C3PBH5 ^@ Function|||Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.|||Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. http://togogenome.org/gene/8478:FGD5 ^@ http://purl.uniprot.org/uniprot/A0A8C3HMB7 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/8478:SENP8 ^@ http://purl.uniprot.org/uniprot/A0A8C3FFM9 ^@ Similarity ^@ Belongs to the peptidase C48 family. http://togogenome.org/gene/8478:GPN3 ^@ http://purl.uniprot.org/uniprot/A0A8C3IRB2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.|||Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/8478:ABRACL ^@ http://purl.uniprot.org/uniprot/A0A8C3HVV0 ^@ Similarity ^@ Belongs to the costars family. http://togogenome.org/gene/8478:SSRP1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HU35 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SSRP1 family.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.|||Nucleus http://togogenome.org/gene/8478:SMAD4 ^@ http://purl.uniprot.org/uniprot/A0A8C3INY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/8478:VEPH1 ^@ http://purl.uniprot.org/uniprot/A0A8C3HZ08 ^@ Similarity ^@ Belongs to the MELT/VEPH family. http://togogenome.org/gene/8478:LOC101937633 ^@ http://purl.uniprot.org/uniprot/A0A8C3IJ59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DAN family.|||Secreted http://togogenome.org/gene/8478:CRB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FT13 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/8478:SLC9A6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IQM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Endosome membrane|||Recycling endosome membrane http://togogenome.org/gene/8478:AKT3 ^@ http://purl.uniprot.org/uniprot/A0A8C3FVM9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily. http://togogenome.org/gene/8478:ZFHX4 ^@ http://purl.uniprot.org/uniprot/A0A8C3H943 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/8478:TSPAN6 ^@ http://purl.uniprot.org/uniprot/A0A8C3HKY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/8478:MAPKAPK2 ^@ http://purl.uniprot.org/uniprot/A0A8C3H664 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/8478:FXR1 ^@ http://purl.uniprot.org/uniprot/A0A8C3EYF5|||http://purl.uniprot.org/uniprot/A0A8C3EZ78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMR1 family.|||Cytoplasmic ribonucleoprotein granule http://togogenome.org/gene/8478:CCNB2 ^@ http://purl.uniprot.org/uniprot/A0A8C3FYP8 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/8478:DCLK2 ^@ http://purl.uniprot.org/uniprot/A0A8C3IU65|||http://purl.uniprot.org/uniprot/A0A8C3IV90|||http://purl.uniprot.org/uniprot/A0A8C3IXX7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. http://togogenome.org/gene/8478:ACSL6 ^@ http://purl.uniprot.org/uniprot/A0A8C3IN37|||http://purl.uniprot.org/uniprot/A0A8C3IQV4 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. http://togogenome.org/gene/8478:PUS7 ^@ http://purl.uniprot.org/uniprot/A0A8C3F241|||http://purl.uniprot.org/uniprot/A0A8C3F4A6 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruD family. http://togogenome.org/gene/8478:SCNN1G ^@ http://purl.uniprot.org/uniprot/A0A8C3F4P6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:PSENEN ^@ http://purl.uniprot.org/uniprot/A0A8C3F3K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEN-2 family.|||Golgi stack membrane|||Membrane http://togogenome.org/gene/8478:XYLB ^@ http://purl.uniprot.org/uniprot/A0A8C3I0D3 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis. http://togogenome.org/gene/8478:MAPK4 ^@ http://purl.uniprot.org/uniprot/A0A8C3IMZ3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/8478:RHBDD1 ^@ http://purl.uniprot.org/uniprot/A0A8C3I4H3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/8478:STEAP4 ^@ http://purl.uniprot.org/uniprot/A0A8C3I8L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STEAP family.|||Endosome membrane|||Membrane http://togogenome.org/gene/8478:RPL17 ^@ http://purl.uniprot.org/uniprot/A0A8C3IPS5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family.