http://togogenome.org/gene/926550:CLDAP_RS09085 ^@ http://purl.uniprot.org/uniprot/I0I3J2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/926550:CLDAP_RS08290 ^@ http://purl.uniprot.org/uniprot/I0I328 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/926550:CLDAP_RS02005 ^@ http://purl.uniprot.org/uniprot/I0HZK0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/926550:CLDAP_RS07230 ^@ http://purl.uniprot.org/uniprot/I0I2H3 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/926550:CLDAP_RS05610 ^@ http://purl.uniprot.org/uniprot/I0I1L1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS09610 ^@ http://purl.uniprot.org/uniprot/I0I3U6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS06885 ^@ http://purl.uniprot.org/uniprot/I0I2B4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS02070 ^@ http://purl.uniprot.org/uniprot/I0HZL3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926550:CLDAP_RS15445 ^@ http://purl.uniprot.org/uniprot/I0I785 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/926550:CLDAP_RS10655 ^@ http://purl.uniprot.org/uniprot/I0I4F8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS01085 ^@ http://purl.uniprot.org/uniprot/I0HZ18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS18075 ^@ http://purl.uniprot.org/uniprot/I0I8S1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS03250 ^@ http://purl.uniprot.org/uniprot/I0I096 ^@ Caution|||Similarity ^@ Belongs to the peptidase S8 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS20440 ^@ http://purl.uniprot.org/uniprot/I0IA53 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/926550:CLDAP_RS02955 ^@ http://purl.uniprot.org/uniprot/I0I037 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS04890 ^@ http://purl.uniprot.org/uniprot/I0I172 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS04025 ^@ http://purl.uniprot.org/uniprot/I0I0Q1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS13390 ^@ http://purl.uniprot.org/uniprot/I0I612 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/926550:CLDAP_RS10820 ^@ http://purl.uniprot.org/uniprot/I0I4J2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/926550:CLDAP_RS06925 ^@ http://purl.uniprot.org/uniprot/I0I2C2 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/926550:CLDAP_RS02390 ^@ http://purl.uniprot.org/uniprot/I0HZS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS10280 ^@ http://purl.uniprot.org/uniprot/I0I484 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS08460 ^@ http://purl.uniprot.org/uniprot/I0I363 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/926550:CLDAP_RS17175 ^@ http://purl.uniprot.org/uniprot/I0I891 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/926550:CLDAP_RS01300 ^@ http://purl.uniprot.org/uniprot/I0HZ59 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/926550:CLDAP_RS09815 ^@ http://purl.uniprot.org/uniprot/I0I3Z0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/926550:CLDAP_RS19555 ^@ http://purl.uniprot.org/uniprot/I0I9M6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell inner membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/926550:CLDAP_RS09985 ^@ http://purl.uniprot.org/uniprot/I0I425 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/926550:CLDAP_RS03510 ^@ http://purl.uniprot.org/uniprot/I0I0E7 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/926550:CLDAP_RS16725 ^@ http://purl.uniprot.org/uniprot/I0I800 ^@ Similarity ^@ Belongs to the terpene synthase family. http://togogenome.org/gene/926550:CLDAP_RS11180 ^@ http://purl.uniprot.org/uniprot/I0I4R8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/926550:CLDAP_RS20130 ^@ http://purl.uniprot.org/uniprot/I0I9Y8 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/926550:CLDAP_RS03705 ^@ http://purl.uniprot.org/uniprot/I0I0I5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/926550:CLDAP_RS07135 ^@ http://purl.uniprot.org/uniprot/I0I2F4 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/926550:CLDAP_RS06310 ^@ http://purl.uniprot.org/uniprot/I0I200 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/926550:CLDAP_RS12185 ^@ http://purl.uniprot.org/uniprot/I0I5C2 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/926550:CLDAP_RS15075 ^@ http://purl.uniprot.org/uniprot/I0I711 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS21670 ^@ http://purl.uniprot.org/uniprot/I0I8M0 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/926550:CLDAP_RS09120 ^@ http://purl.uniprot.org/uniprot/I0I3J9 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/926550:CLDAP_RS02145 ^@ http://purl.uniprot.org/uniprot/I0HZM8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell inner membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/926550:CLDAP_RS09885 ^@ http://purl.uniprot.org/uniprot/I0I404 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS01520 ^@ http://purl.uniprot.org/uniprot/I0HZA2 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/926550:CLDAP_RS06405 ^@ http://purl.uniprot.org/uniprot/I0I219 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS20495 ^@ http://purl.uniprot.org/uniprot/I0IA64 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS10115 ^@ http://purl.uniprot.org/uniprot/I0I450 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS00700 ^@ http://purl.uniprot.org/uniprot/I0HYU1 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/926550:CLDAP_RS08020 ^@ http://purl.uniprot.org/uniprot/I0I2X3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/926550:CLDAP_RS00765 ^@ http://purl.uniprot.org/uniprot/I0HYV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS07360 ^@ http://purl.uniprot.org/uniprot/I0I2J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS23460 ^@ http://purl.uniprot.org/uniprot/I0I0J5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS17955 ^@ http://purl.uniprot.org/uniprot/I0I8P7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell inner membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS11040 ^@ http://purl.uniprot.org/uniprot/I0I4P0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS06920 ^@ http://purl.uniprot.org/uniprot/I0I2C1 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/926550:CLDAP_RS21080 ^@ http://purl.uniprot.org/uniprot/I0I2Z7 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS00690 ^@ http://purl.uniprot.org/uniprot/I0HYT9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS00345 ^@ http://purl.uniprot.org/uniprot/I0HYM1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS09225 ^@ http://purl.uniprot.org/uniprot/I0I3L9 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS02900 ^@ http://purl.uniprot.org/uniprot/I0I026 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS05555 ^@ http://purl.uniprot.org/uniprot/I0I1J9 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/926550:CLDAP_RS12745 ^@ http://purl.uniprot.org/uniprot/I0I5N4 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/926550:CLDAP_RS08335 ^@ http://purl.uniprot.org/uniprot/I0I337 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS09325 ^@ http://purl.uniprot.org/uniprot/I0I3N7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS10690 ^@ http://purl.uniprot.org/uniprot/I0I4G6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/926550:CLDAP_RS03590 ^@ http://purl.uniprot.org/uniprot/I0I0G2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/926550:CLDAP_RS08095 ^@ http://purl.uniprot.org/uniprot/I0I2Y6 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/926550:CLDAP_RS18230 ^@ http://purl.uniprot.org/uniprot/I0I8V3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 51 family. http://togogenome.org/gene/926550:CLDAP_RS12965 ^@ http://purl.uniprot.org/uniprot/I0I5S7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/926550:CLDAP_RS13385 ^@ http://purl.uniprot.org/uniprot/I0I611 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/926550:CLDAP_RS17450 ^@ http://purl.uniprot.org/uniprot/I0I8E6 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/926550:CLDAP_RS12085 ^@ http://purl.uniprot.org/uniprot/I0I598 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiN family.|||Cell inner membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/926550:CLDAP_RS14345 ^@ http://purl.uniprot.org/uniprot/I0I6L1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS07915 ^@ http://purl.uniprot.org/uniprot/I0I2V2 ^@ Similarity ^@ Belongs to the Lgt family. http://togogenome.org/gene/926550:CLDAP_RS17930 ^@ http://purl.uniprot.org/uniprot/I0I8P2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS07375 ^@ http://purl.uniprot.org/uniprot/I0I2K2 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/926550:CLDAP_RS07560 ^@ http://purl.uniprot.org/uniprot/I0I2N3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/926550:CLDAP_RS18975 ^@ http://purl.uniprot.org/uniprot/I0I9A4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/926550:CLDAP_RS16945 ^@ http://purl.uniprot.org/uniprot/I0I844 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS19945 ^@ http://purl.uniprot.org/uniprot/I0I9V3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS10785 ^@ http://purl.uniprot.org/uniprot/I0I4I5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/926550:CLDAP_RS07845 ^@ http://purl.uniprot.org/uniprot/I0I2T8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/926550:CLDAP_RS08840 ^@ http://purl.uniprot.org/uniprot/I0I3E1 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/926550:CLDAP_RS12385 ^@ http://purl.uniprot.org/uniprot/I0I5G3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/926550:CLDAP_RS06605 ^@ http://purl.uniprot.org/uniprot/I0I260 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/926550:CLDAP_RS07590 ^@ http://purl.uniprot.org/uniprot/I0I2N9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/926550:CLDAP_RS21370 ^@ http://purl.uniprot.org/uniprot/I0I675 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/926550:CLDAP_RS01545 ^@ http://purl.uniprot.org/uniprot/I0HZA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS18875 ^@ http://purl.uniprot.org/uniprot/I0I984 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/926550:CLDAP_RS20980 ^@ http://purl.uniprot.org/uniprot/I0I204 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/926550:CLDAP_RS21010 ^@ http://purl.uniprot.org/uniprot/I0I2C7 ^@ Caution|||Similarity ^@ Belongs to the peptidase S8 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS01985 ^@ http://purl.uniprot.org/uniprot/I0HZJ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/926550:CLDAP_RS20465 ^@ http://purl.uniprot.org/uniprot/I0IA58 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926550:CLDAP_RS00905 ^@ http://purl.uniprot.org/uniprot/I0HYY0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell inner membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/926550:CLDAP_RS19995 ^@ http://purl.uniprot.org/uniprot/I0I9W3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS10295 ^@ http://purl.uniprot.org/uniprot/I0I487 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/926550:CLDAP_RS18885 ^@ http://purl.uniprot.org/uniprot/I0I986 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/926550:CLDAP_RS17160 ^@ http://purl.uniprot.org/uniprot/I0I888 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/926550:CLDAP_RS08945 ^@ http://purl.uniprot.org/uniprot/I0I3G1 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/926550:CLDAP_RS03710 ^@ http://purl.uniprot.org/uniprot/I0I0I6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/926550:CLDAP_RS19595 ^@ http://purl.uniprot.org/uniprot/I0I9N5 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/926550:CLDAP_RS17235 ^@ http://purl.uniprot.org/uniprot/I0I8A2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/926550:CLDAP_RS00860 ^@ http://purl.uniprot.org/uniprot/I0HYX1 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/926550:CLDAP_RS10435 ^@ http://purl.uniprot.org/uniprot/I0I4B5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/926550:CLDAP_RS18995 ^@ http://purl.uniprot.org/uniprot/I0I9A8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS18795 ^@ http://purl.uniprot.org/uniprot/I0I968 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/926550:CLDAP_RS17220 ^@ http://purl.uniprot.org/uniprot/I0I8A0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/926550:CLDAP_RS18625 ^@ http://purl.uniprot.org/uniprot/I0I935 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/926550:CLDAP_RS04385 ^@ http://purl.uniprot.org/uniprot/I0I0X1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926550:CLDAP_RS18395 ^@ http://purl.uniprot.org/uniprot/I0I8Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS04760 ^@ http://purl.uniprot.org/uniprot/I0I147 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS02020 ^@ http://purl.uniprot.org/uniprot/I0HZK3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926550:CLDAP_RS06200 ^@ http://purl.uniprot.org/uniprot/I0I1X7 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/926550:CLDAP_RS04395 ^@ http://purl.uniprot.org/uniprot/I0I0X3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell inner membrane|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/926550:CLDAP_RS02445 ^@ http://purl.uniprot.org/uniprot/I0HZT7 ^@ Similarity ^@ Belongs to the RimK family. LysX subfamily. http://togogenome.org/gene/926550:CLDAP_RS10425 ^@ http://purl.uniprot.org/uniprot/I0I4B3 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/926550:CLDAP_RS03450 ^@ http://purl.uniprot.org/uniprot/I0I0D5 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/926550:CLDAP_RS17670 ^@ http://purl.uniprot.org/uniprot/I0I8J1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/926550:CLDAP_RS00190 ^@ http://purl.uniprot.org/uniprot/I0HYJ0 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/926550:CLDAP_RS04420 ^@ http://purl.uniprot.org/uniprot/I0I0X8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell inner membrane|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926550:CLDAP_RS23330 ^@ http://purl.uniprot.org/uniprot/I0I7J3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS00910 ^@ http://purl.uniprot.org/uniprot/I0HYY1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell inner membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/926550:CLDAP_RS09685 ^@ http://purl.uniprot.org/uniprot/I0I3W2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/926550:CLDAP_RS14050 ^@ http://purl.uniprot.org/uniprot/I0I6E7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS10340 ^@ http://purl.uniprot.org/uniprot/I0I496 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/926550:CLDAP_RS00280 ^@ http://purl.uniprot.org/uniprot/I0HYK8 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/926550:CLDAP_RS09530 ^@ http://purl.uniprot.org/uniprot/I0I3S8 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/926550:CLDAP_RS02530 ^@ http://purl.uniprot.org/uniprot/I0HZV4 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/926550:CLDAP_RS06165 ^@ http://purl.uniprot.org/uniprot/I0I1X0 ^@ Similarity ^@ Belongs to the CRISPR-associated Csm4 family. http://togogenome.org/gene/926550:CLDAP_RS19860 ^@ http://purl.uniprot.org/uniprot/I0I9T6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/926550:CLDAP_RS18690 ^@ http://purl.uniprot.org/uniprot/I0I949 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/926550:CLDAP_RS19000 ^@ http://purl.uniprot.org/uniprot/I0I9A9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS11475 ^@ http://purl.uniprot.org/uniprot/I0I4X5 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-72 and Arg-75) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. http://togogenome.org/gene/926550:CLDAP_RS13545 ^@ http://purl.uniprot.org/uniprot/I0I644 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS09490 ^@ http://purl.uniprot.org/uniprot/I0I3S0 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/926550:CLDAP_RS14070 ^@ http://purl.uniprot.org/uniprot/I0I6F2 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/926550:CLDAP_RS14780 ^@ http://purl.uniprot.org/uniprot/I0I6V1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/926550:CLDAP_RS18730 ^@ http://purl.uniprot.org/uniprot/I0I956 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS10180 ^@ http://purl.uniprot.org/uniprot/I0I463 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/926550:CLDAP_RS19770 ^@ http://purl.uniprot.org/uniprot/I0I9R8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS08360 ^@ http://purl.uniprot.org/uniprot/I0I342 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/926550:CLDAP_RS15675 ^@ http://purl.uniprot.org/uniprot/I0I7D0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS05585 ^@ http://purl.uniprot.org/uniprot/I0I1K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS08410 ^@ http://purl.uniprot.org/uniprot/I0I352 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS06855 ^@ http://purl.uniprot.org/uniprot/I0I2A8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS01515 ^@ http://purl.uniprot.org/uniprot/I0HZA1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/926550:CLDAP_RS04425 ^@ http://purl.uniprot.org/uniprot/I0I0X9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell inner membrane|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926550:CLDAP_RS11300 ^@ http://purl.uniprot.org/uniprot/I0I4U1 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/926550:CLDAP_RS07805 ^@ http://purl.uniprot.org/uniprot/I0I2T1 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/926550:CLDAP_RS09535 ^@ http://purl.uniprot.org/uniprot/I0I3S9 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/926550:CLDAP_RS02980 ^@ http://purl.uniprot.org/uniprot/I0I042 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS13665 ^@ http://purl.uniprot.org/uniprot/I0I668 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/926550:CLDAP_RS13345 ^@ http://purl.uniprot.org/uniprot/I0I603 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS15840 ^@ http://purl.uniprot.org/uniprot/I0I7G3 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/926550:CLDAP_RS12505 ^@ http://purl.uniprot.org/uniprot/I0I5I8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS16790 ^@ http://purl.uniprot.org/uniprot/I0I814 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/926550:CLDAP_RS00880 ^@ http://purl.uniprot.org/uniprot/I0HYX5 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/926550:CLDAP_RS18310 ^@ http://purl.uniprot.org/uniprot/I0I8W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS06350 ^@ http://purl.uniprot.org/uniprot/I0I208 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/926550:CLDAP_RS16980 ^@ http://purl.uniprot.org/uniprot/I0I851 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/926550:CLDAP_RS19145 ^@ http://purl.uniprot.org/uniprot/I0I9D8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS03850 ^@ http://purl.uniprot.org/uniprot/I0I0L6 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/926550:CLDAP_RS02010 ^@ http://purl.uniprot.org/uniprot/I0HZK1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/926550:CLDAP_RS02735 ^@ http://purl.uniprot.org/uniprot/I0HZZ4 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926550:CLDAP_RS21215 ^@ http://purl.uniprot.org/uniprot/I0I474 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/926550:CLDAP_RS00295 ^@ http://purl.uniprot.org/uniprot/I0HYL1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MCH family.|||Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS18735 ^@ http://purl.uniprot.org/uniprot/I0I957 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS00465 ^@ http://purl.uniprot.org/uniprot/I0HYP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS18335 ^@ http://purl.uniprot.org/uniprot/I0I8X4 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit. http://togogenome.org/gene/926550:CLDAP_RS13435 ^@ http://purl.uniprot.org/uniprot/I0I621 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS20500 ^@ http://purl.uniprot.org/uniprot/I0IA65 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/926550:CLDAP_RS06735 ^@ http://purl.uniprot.org/uniprot/I0I282 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS10210 ^@ http://purl.uniprot.org/uniprot/I0I471 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HsdR family.|||Subunit R is required for both nuclease and ATPase activities, but not for modification.|||The type I restriction/modification system is composed of three polypeptides R, M and S. http://togogenome.org/gene/926550:CLDAP_RS09300 ^@ http://purl.uniprot.org/uniprot/I0I3N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS05070 ^@ http://purl.uniprot.org/uniprot/I0I1A8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS05785 ^@ http://purl.uniprot.org/uniprot/I0I1P6 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS11815 ^@ http://purl.uniprot.org/uniprot/I0I544 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/926550:CLDAP_RS06175 ^@ http://purl.uniprot.org/uniprot/I0I1X2 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm2 family.|||This subunit may be involved in monitoring complementarity of crRNA and target RNA. http://togogenome.org/gene/926550:CLDAP_RS09545 ^@ http://purl.uniprot.org/uniprot/I0I3T1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS00105 ^@ http://purl.uniprot.org/uniprot/I0HYH2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/926550:CLDAP_RS11010 ^@ http://purl.uniprot.org/uniprot/I0I4N4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/926550:CLDAP_RS03405 ^@ http://purl.uniprot.org/uniprot/I0I0C6 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/926550:CLDAP_RS06420 ^@ http://purl.uniprot.org/uniprot/I0I222 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/926550:CLDAP_RS04115 ^@ http://purl.uniprot.org/uniprot/I0I0R9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS12190 ^@ http://purl.uniprot.org/uniprot/I0I5C3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS02100 ^@ http://purl.uniprot.org/uniprot/I0HZL9 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/926550:CLDAP_RS04510 ^@ http://purl.uniprot.org/uniprot/I0I0Z6 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/926550:CLDAP_RS18165 ^@ http://purl.uniprot.org/uniprot/I0I8U0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/926550:CLDAP_RS08975 ^@ http://purl.uniprot.org/uniprot/I0I3G7 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/926550:CLDAP_RS17750 ^@ http://purl.uniprot.org/uniprot/I0I8K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS01305 ^@ http://purl.uniprot.org/uniprot/I0HZ60 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/926550:CLDAP_RS19955 ^@ http://purl.uniprot.org/uniprot/I0I9V5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS05415 ^@ http://purl.uniprot.org/uniprot/I0I1H3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/926550:CLDAP_RS16010 ^@ http://purl.uniprot.org/uniprot/I0I7J9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/926550:CLDAP_RS05695 ^@ http://purl.uniprot.org/uniprot/I0I1M8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS16025 ^@ http://purl.uniprot.org/uniprot/I0I7K2 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/926550:CLDAP_RS03160 ^@ http://purl.uniprot.org/uniprot/I0I077 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS13025 ^@ http://purl.uniprot.org/uniprot/I0I5T9 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/926550:CLDAP_RS18990 ^@ http://purl.uniprot.org/uniprot/I0I9A7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS05315 ^@ http://purl.uniprot.org/uniprot/I0I1F4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/926550:CLDAP_RS07820 ^@ http://purl.uniprot.org/uniprot/I0I2T3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS09835 ^@ http://purl.uniprot.org/uniprot/I0I3Z4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/926550:CLDAP_RS03315 ^@ http://purl.uniprot.org/uniprot/I0I0A8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS00470 ^@ http://purl.uniprot.org/uniprot/I0HYP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS15505 ^@ http://purl.uniprot.org/uniprot/I0I797 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/926550:CLDAP_RS03410 ^@ http://purl.uniprot.org/uniprot/I0I0C7 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/926550:CLDAP_RS11265 ^@ http://purl.uniprot.org/uniprot/I0I4T5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS20075 ^@ http://purl.uniprot.org/uniprot/I0I9X9 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/926550:CLDAP_RS17400 ^@ http://purl.uniprot.org/uniprot/I0I8D5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/926550:CLDAP_RS19765 ^@ http://purl.uniprot.org/uniprot/I0I9R7 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/926550:CLDAP_RS11565 ^@ http://purl.uniprot.org/uniprot/I0I4Z4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/926550:CLDAP_RS14065 ^@ http://purl.uniprot.org/uniprot/I0I6F1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/926550:CLDAP_RS00575 ^@ http://purl.uniprot.org/uniprot/I0HYR6 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/926550:CLDAP_RS11030 ^@ http://purl.uniprot.org/uniprot/I0I4N8 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/926550:CLDAP_RS00870 ^@ http://purl.uniprot.org/uniprot/I0HYX3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS15465 ^@ http://purl.uniprot.org/uniprot/I0I789 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS05345 ^@ http://purl.uniprot.org/uniprot/I0I1G0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS19440 ^@ http://purl.uniprot.org/uniprot/I0I9K0 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/926550:CLDAP_RS11920 ^@ http://purl.uniprot.org/uniprot/I0I565 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/926550:CLDAP_RS11880 ^@ http://purl.uniprot.org/uniprot/I0I557 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/926550:CLDAP_RS15460 ^@ http://purl.uniprot.org/uniprot/I0I788 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/926550:CLDAP_RS08285 ^@ http://purl.uniprot.org/uniprot/I0I327 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS04525 ^@ http://purl.uniprot.org/uniprot/I0I0Z9 ^@ Similarity|||Subunit ^@ Belongs to the methylthioribose kinase family.|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS18720 ^@ http://purl.uniprot.org/uniprot/I0I954 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS15895 ^@ http://purl.uniprot.org/uniprot/I0I7H4 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/926550:CLDAP_RS09150 ^@ http://purl.uniprot.org/uniprot/I0I3K4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/926550:CLDAP_RS20485 ^@ http://purl.uniprot.org/uniprot/I0IA62 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/926550:CLDAP_RS09135 ^@ http://purl.uniprot.org/uniprot/I0I3K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS12480 ^@ http://purl.uniprot.org/uniprot/I0I5I3 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/926550:CLDAP_RS12955 ^@ http://purl.uniprot.org/uniprot/I0I5S5 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/926550:CLDAP_RS05380 ^@ http://purl.uniprot.org/uniprot/I0I1G6 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/926550:CLDAP_RS01965 ^@ http://purl.uniprot.org/uniprot/I0HZJ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/926550:CLDAP_RS01940 ^@ http://purl.uniprot.org/uniprot/I0HZI6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/926550:CLDAP_RS00010 ^@ http://purl.uniprot.org/uniprot/I0HYF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS06340 ^@ http://purl.uniprot.org/uniprot/I0I206 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS12430 ^@ http://purl.uniprot.org/uniprot/I0I5H3 ^@ Cofactor|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily.|||Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/926550:CLDAP_RS20015 ^@ http://purl.uniprot.org/uniprot/I0I9W7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M3B family.|||Binds 1 zinc ion.|||Has oligopeptidase activity and degrades a variety of small bioactive peptides. http://togogenome.org/gene/926550:CLDAP_RS02540 ^@ http://purl.uniprot.org/uniprot/I0HZV6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/926550:CLDAP_RS16250 ^@ http://purl.uniprot.org/uniprot/I0I7Q0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS13525 ^@ http://purl.uniprot.org/uniprot/I0I640 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS07685 ^@ http://purl.uniprot.org/uniprot/I0I2Q8 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/926550:CLDAP_RS04005 ^@ http://purl.uniprot.org/uniprot/I0I0P7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/926550:CLDAP_RS21020 ^@ http://purl.uniprot.org/uniprot/I0I2F9 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS17690 ^@ http://purl.uniprot.org/uniprot/I0I8J5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS07110 ^@ http://purl.uniprot.org/uniprot/I0I2E9 ^@ Similarity ^@ Belongs to the glycosyltransferase 2 family. http://togogenome.org/gene/926550:CLDAP_RS04035 ^@ http://purl.uniprot.org/uniprot/I0I0Q3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS17085 ^@ http://purl.uniprot.org/uniprot/I0I873 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/926550:CLDAP_RS00925 ^@ http://purl.uniprot.org/uniprot/I0HYY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS17435 ^@ http://purl.uniprot.org/uniprot/I0I8E2 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/926550:CLDAP_RS15165 ^@ http://purl.uniprot.org/uniprot/I0I729 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/926550:CLDAP_RS01420 ^@ http://purl.uniprot.org/uniprot/I0HZ82 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/926550:CLDAP_RS12510 ^@ http://purl.uniprot.org/uniprot/I0I5I9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS12895 ^@ http://purl.uniprot.org/uniprot/I0I5R2 ^@ Similarity ^@ Belongs to the diphosphomevalonate decarboxylase family. http://togogenome.org/gene/926550:CLDAP_RS13095 ^@ http://purl.uniprot.org/uniprot/I0I5V3 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/926550:CLDAP_RS08105 ^@ http://purl.uniprot.org/uniprot/I0I2Y8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/926550:CLDAP_RS04450 ^@ http://purl.uniprot.org/uniprot/I0I0Y4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS03195 ^@ http://purl.uniprot.org/uniprot/I0I084 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/926550:CLDAP_RS01060 ^@ http://purl.uniprot.org/uniprot/I0HZ12 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS12620 ^@ http://purl.uniprot.org/uniprot/I0I5L0 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/926550:CLDAP_RS05835 ^@ http://purl.uniprot.org/uniprot/I0I1Q6 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/926550:CLDAP_RS00140 ^@ http://purl.uniprot.org/uniprot/I0HYI0 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/926550:CLDAP_RS20025 ^@ http://purl.uniprot.org/uniprot/I0I9W9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS00755 ^@ http://purl.uniprot.org/uniprot/I0HYV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/926550:CLDAP_RS04455 ^@ http://purl.uniprot.org/uniprot/I0I0Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS02520 ^@ http://purl.uniprot.org/uniprot/I0HZV2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/926550:CLDAP_RS06900 ^@ http://purl.uniprot.org/uniprot/I0I2B7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS15375 ^@ http://purl.uniprot.org/uniprot/I0I771 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/926550:CLDAP_RS02265 ^@ http://purl.uniprot.org/uniprot/I0HZQ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS20515 ^@ http://purl.uniprot.org/uniprot/I0IA68 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS03210 ^@ http://purl.uniprot.org/uniprot/I0I087 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/926550:CLDAP_RS08585 ^@ http://purl.uniprot.org/uniprot/I0I388 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS19735 ^@ http://purl.uniprot.org/uniprot/I0I9R1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M32 family.|||Binds 1 zinc ion per subunit.|||Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. http://togogenome.org/gene/926550:CLDAP_RS09750 ^@ http://purl.uniprot.org/uniprot/I0I3X6 ^@ Cofactor ^@ Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/926550:CLDAP_RS18815 ^@ http://purl.uniprot.org/uniprot/I0I972 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/926550:CLDAP_RS12925 ^@ http://purl.uniprot.org/uniprot/I0I5R9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS19055 ^@ http://purl.uniprot.org/uniprot/I0I9C0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/926550:CLDAP_RS21045 ^@ http://purl.uniprot.org/uniprot/I0I2S3 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/926550:CLDAP_RS12600 ^@ http://purl.uniprot.org/uniprot/I0I5K7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS00185 ^@ http://purl.uniprot.org/uniprot/I0HYI9 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/926550:CLDAP_RS17230 ^@ http://purl.uniprot.org/uniprot/I0I8A1 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/926550:CLDAP_RS06210 ^@ http://purl.uniprot.org/uniprot/I0I1X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS16085 ^@ http://purl.uniprot.org/uniprot/I0I7L4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS15915 ^@ http://purl.uniprot.org/uniprot/I0I7H8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS21450 ^@ http://purl.uniprot.org/uniprot/I0I6S8 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/926550:CLDAP_RS13625 ^@ http://purl.uniprot.org/uniprot/I0I660 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926550:CLDAP_RS19445 ^@ http://purl.uniprot.org/uniprot/I0I9K2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/926550:CLDAP_RS05680 ^@ http://purl.uniprot.org/uniprot/I0I1M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS16425 ^@ http://purl.uniprot.org/uniprot/I0I7T4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS20000 ^@ http://purl.uniprot.org/uniprot/I0I9W4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS14740 ^@ http://purl.uniprot.org/uniprot/I0I6U3 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/926550:CLDAP_RS17090 ^@ http://purl.uniprot.org/uniprot/I0I874 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS03535 ^@ http://purl.uniprot.org/uniprot/I0I0F2 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/926550:CLDAP_RS08720 ^@ http://purl.uniprot.org/uniprot/I0I3B6 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/926550:CLDAP_RS12415 ^@ http://purl.uniprot.org/uniprot/I0I5H0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS16890 ^@ http://purl.uniprot.org/uniprot/I0I833 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS19250 ^@ http://purl.uniprot.org/uniprot/I0I9F9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/926550:CLDAP_RS03265 ^@ http://purl.uniprot.org/uniprot/I0I099 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/926550:CLDAP_RS13045 ^@ http://purl.uniprot.org/uniprot/I0I5U3 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/926550:CLDAP_RS04545 ^@ http://purl.uniprot.org/uniprot/I0I103 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/926550:CLDAP_RS12275 ^@ http://purl.uniprot.org/uniprot/I0I5E1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS18725 ^@ http://purl.uniprot.org/uniprot/I0I955 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/926550:CLDAP_RS13450 ^@ http://purl.uniprot.org/uniprot/I0I624 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/926550:CLDAP_RS01400 ^@ http://purl.uniprot.org/uniprot/I0HZ78 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/926550:CLDAP_RS11305 ^@ http://purl.uniprot.org/uniprot/I0I4U2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L-fucose isomerase family.|||Converts the aldose L-fucose into the corresponding ketose L-fuculose.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS07480 ^@ http://purl.uniprot.org/uniprot/I0I2M2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/926550:CLDAP_RS02845 ^@ http://purl.uniprot.org/uniprot/I0I015 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS13125 ^@ http://purl.uniprot.org/uniprot/I0I5V9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS14760 ^@ http://purl.uniprot.org/uniprot/I0I6U7 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS23055 ^@ http://purl.uniprot.org/uniprot/I0I842 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS17120 ^@ http://purl.uniprot.org/uniprot/I0I880 ^@ Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/926550:CLDAP_RS11345 ^@ http://purl.uniprot.org/uniprot/I0I4V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS18510 ^@ http://purl.uniprot.org/uniprot/I0I910 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/926550:CLDAP_RS03690 ^@ http://purl.uniprot.org/uniprot/I0I0I2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS12205 ^@ http://purl.uniprot.org/uniprot/I0I5C6 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/926550:CLDAP_RS06870 ^@ http://purl.uniprot.org/uniprot/I0I2B1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS05755 ^@ http://purl.uniprot.org/uniprot/I0I1P0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS20945 ^@ http://purl.uniprot.org/uniprot/I0I1T3 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/926550:CLDAP_RS09075 ^@ http://purl.uniprot.org/uniprot/I0I3J0 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/926550:CLDAP_RS09425 ^@ http://purl.uniprot.org/uniprot/I0I3Q7 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/926550:CLDAP_RS02370 ^@ http://purl.uniprot.org/uniprot/I0HZS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S41B family.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS16105 ^@ http://purl.uniprot.org/uniprot/I0I7L8 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/926550:CLDAP_RS17770 ^@ http://purl.uniprot.org/uniprot/I0I8L0 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/926550:CLDAP_RS09570 ^@ http://purl.uniprot.org/uniprot/I0I3T7 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS12035 ^@ http://purl.uniprot.org/uniprot/I0I588 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/926550:CLDAP_RS15240 ^@ http://purl.uniprot.org/uniprot/I0I744 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS18090 ^@ http://purl.uniprot.org/uniprot/I0I8S4 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/926550:CLDAP_RS02565 ^@ http://purl.uniprot.org/uniprot/I0HZW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS09775 ^@ http://purl.uniprot.org/uniprot/I0I3Y2 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/926550:CLDAP_RS15580 ^@ http://purl.uniprot.org/uniprot/I0I7B2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS17835 ^@ http://purl.uniprot.org/uniprot/I0I8M3 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/926550:CLDAP_RS16885 ^@ http://purl.uniprot.org/uniprot/I0I832 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS21285 ^@ http://purl.uniprot.org/uniprot/I0I525 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS10525 ^@ http://purl.uniprot.org/uniprot/I0I4D3 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruD family.|||Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs. http://togogenome.org/gene/926550:CLDAP_RS07930 ^@ http://purl.uniprot.org/uniprot/I0I2V5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS17395 ^@ http://purl.uniprot.org/uniprot/I0I8D4 ^@ Caution|||Similarity ^@ Belongs to the peptidase S8 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS14420 ^@ http://purl.uniprot.org/uniprot/I0I6M6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/926550:CLDAP_RS13660 ^@ http://purl.uniprot.org/uniprot/I0I667 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS03335 ^@ http://purl.uniprot.org/uniprot/I0I0B2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/926550:CLDAP_RS19115 ^@ http://purl.uniprot.org/uniprot/I0I9D2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS12265 ^@ http://purl.uniprot.org/uniprot/I0I5D8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase S45 family.|||Binds 1 Ca(2+) ion per dimer. http://togogenome.org/gene/926550:CLDAP_RS04435 ^@ http://purl.uniprot.org/uniprot/I0I0Y1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926550:CLDAP_RS15335 ^@ http://purl.uniprot.org/uniprot/I0I763 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS04560 ^@ http://purl.uniprot.org/uniprot/I0I106 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.|||Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component). http://togogenome.org/gene/926550:CLDAP_RS09970 ^@ http://purl.uniprot.org/uniprot/I0I422 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/926550:CLDAP_RS03105 ^@ http://purl.uniprot.org/uniprot/I0I066 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS23220 ^@ http://purl.uniprot.org/uniprot/I0HYH4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS20865 ^@ http://purl.uniprot.org/uniprot/I0I190 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/926550:CLDAP_RS14310 ^@ http://purl.uniprot.org/uniprot/I0I6K4 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/926550:CLDAP_RS06240 ^@ http://purl.uniprot.org/uniprot/I0I1Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS08610 ^@ http://purl.uniprot.org/uniprot/I0I394 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS15090 ^@ http://purl.uniprot.org/uniprot/I0I714 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS08845 ^@ http://purl.uniprot.org/uniprot/I0I3E2 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/926550:CLDAP_RS18340 ^@ http://purl.uniprot.org/uniprot/I0I8X5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS20490 ^@ http://purl.uniprot.org/uniprot/I0IA63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS12105 ^@ http://purl.uniprot.org/uniprot/I0I5A5 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/926550:CLDAP_RS05330 ^@ http://purl.uniprot.org/uniprot/I0I1F7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell inner membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS20460 ^@ http://purl.uniprot.org/uniprot/I0IA57 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family. LysK subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS04200 ^@ http://purl.uniprot.org/uniprot/I0I0T5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/926550:CLDAP_RS10545 ^@ http://purl.uniprot.org/uniprot/I0I4D6 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS06660 ^@ http://purl.uniprot.org/uniprot/I0I271 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/926550:CLDAP_RS06510 ^@ http://purl.uniprot.org/uniprot/I0I241 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS02050 ^@ http://purl.uniprot.org/uniprot/I0HZK9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/926550:CLDAP_RS00025 ^@ http://purl.uniprot.org/uniprot/I0HYF7 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/926550:CLDAP_RS10485 ^@ http://purl.uniprot.org/uniprot/I0I4C5 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/926550:CLDAP_RS15635 ^@ http://purl.uniprot.org/uniprot/I0I7C2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell inner membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/926550:CLDAP_RS20295 ^@ http://purl.uniprot.org/uniprot/I0IA24 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/926550:CLDAP_RS20470 ^@ http://purl.uniprot.org/uniprot/I0IA59 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. LysZ subfamily.|||Catalyzes the phosphorylation of LysW-gamma-alpha-aminoadipate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS14530 ^@ http://purl.uniprot.org/uniprot/I0I6Q0 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 Fe cation per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/926550:CLDAP_RS06490 ^@ http://purl.uniprot.org/uniprot/I0I237 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/926550:CLDAP_RS06810 ^@ http://purl.uniprot.org/uniprot/I0I298 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS01125 ^@ http://purl.uniprot.org/uniprot/I0HZ26 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/926550:CLDAP_RS03570 ^@ http://purl.uniprot.org/uniprot/I0I0F8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PucC family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS07365 ^@ http://purl.uniprot.org/uniprot/I0I2K0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS16035 ^@ http://purl.uniprot.org/uniprot/I0I7K4 ^@ Function|||Similarity ^@ Belongs to the anhydro-N-acetylmuramic acid kinase family.|||Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/926550:CLDAP_RS19940 ^@ http://purl.uniprot.org/uniprot/I0I9V2 ^@ Similarity ^@ Belongs to the UPRTase family. http://togogenome.org/gene/926550:CLDAP_RS20775 ^@ http://purl.uniprot.org/uniprot/I0I0I9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/926550:CLDAP_RS11720 ^@ http://purl.uniprot.org/uniprot/I0I526 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/926550:CLDAP_RS08085 ^@ http://purl.uniprot.org/uniprot/I0I2Y4 ^@ Function ^@ CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/926550:CLDAP_RS09660 ^@ http://purl.uniprot.org/uniprot/I0I3V7 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926550:CLDAP_RS02015 ^@ http://purl.uniprot.org/uniprot/I0HZK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/926550:CLDAP_RS15905 ^@ http://purl.uniprot.org/uniprot/I0I7H6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS06615 ^@ http://purl.uniprot.org/uniprot/I0I262 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/926550:CLDAP_RS00895 ^@ http://purl.uniprot.org/uniprot/I0HYX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS19310 ^@ http://purl.uniprot.org/uniprot/I0I9H0 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Monomer. http://togogenome.org/gene/926550:CLDAP_RS01495 ^@ http://purl.uniprot.org/uniprot/I0HZ97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS05945 ^@ http://purl.uniprot.org/uniprot/I0I1S7 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/926550:CLDAP_RS14090 ^@ http://purl.uniprot.org/uniprot/I0I6F6 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/926550:CLDAP_RS00940 ^@ http://purl.uniprot.org/uniprot/I0HYY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS17185 ^@ http://purl.uniprot.org/uniprot/I0I893 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS14870 ^@ http://purl.uniprot.org/uniprot/I0I6W9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS17240 ^@ http://purl.uniprot.org/uniprot/I0I8A3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS11495 ^@ http://purl.uniprot.org/uniprot/I0I4X9 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926550:CLDAP_RS12440 ^@ http://purl.uniprot.org/uniprot/I0I5H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS09965 ^@ http://purl.uniprot.org/uniprot/I0I421 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/926550:CLDAP_RS09760 ^@ http://purl.uniprot.org/uniprot/I0I3X8 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/926550:CLDAP_RS07670 ^@ http://purl.uniprot.org/uniprot/I0I2Q5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MsrQ family.|||Binds 1 FMN per subunit.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Cell inner membrane|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Membrane|||Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain. http://togogenome.org/gene/926550:CLDAP_RS09735 ^@ http://purl.uniprot.org/uniprot/I0I3X3 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS21210 ^@ http://purl.uniprot.org/uniprot/I0I464 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/926550:CLDAP_RS20700 ^@ http://purl.uniprot.org/uniprot/I0HZN0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpB RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpA.|||Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS05355 ^@ http://purl.uniprot.org/uniprot/I0I1G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS19700 ^@ http://purl.uniprot.org/uniprot/I0I9Q5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/926550:CLDAP_RS00865 ^@ http://purl.uniprot.org/uniprot/I0HYX2 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/926550:CLDAP_RS07270 ^@ http://purl.uniprot.org/uniprot/I0I2I1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS00170 ^@ http://purl.uniprot.org/uniprot/I0HYI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/926550:CLDAP_RS16580 ^@ http://purl.uniprot.org/uniprot/I0I7W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS08940 ^@ http://purl.uniprot.org/uniprot/I0I3G0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS06215 ^@ http://purl.uniprot.org/uniprot/I0I1Y0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS08740 ^@ http://purl.uniprot.org/uniprot/I0I3C0 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/926550:CLDAP_RS13765 ^@ http://purl.uniprot.org/uniprot/I0I690 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/926550:CLDAP_RS00740 ^@ http://purl.uniprot.org/uniprot/I0HYU7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/926550:CLDAP_RS03295 ^@ http://purl.uniprot.org/uniprot/I0I0A4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase S45 family.|||Binds 1 Ca(2+) ion per dimer. http://togogenome.org/gene/926550:CLDAP_RS19285 ^@ http://purl.uniprot.org/uniprot/I0I9G5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS06170 ^@ http://purl.uniprot.org/uniprot/I0I1X1 ^@ Similarity ^@ Belongs to the CRISPR-associated Csm3 family. http://togogenome.org/gene/926550:CLDAP_RS14680 ^@ http://purl.uniprot.org/uniprot/I0I6T0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/926550:CLDAP_RS10855 ^@ http://purl.uniprot.org/uniprot/I0I4J9 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/926550:CLDAP_RS20785 ^@ http://purl.uniprot.org/uniprot/I0I0K8 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/926550:CLDAP_RS17145 ^@ http://purl.uniprot.org/uniprot/I0I885 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS17010 ^@ http://purl.uniprot.org/uniprot/I0I857 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS13670 ^@ http://purl.uniprot.org/uniprot/I0I669 ^@ Similarity ^@ Belongs to the peptidase C69 family. http://togogenome.org/gene/926550:CLDAP_RS19495 ^@ http://purl.uniprot.org/uniprot/I0I9L3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS14125 ^@ http://purl.uniprot.org/uniprot/I0I6G4 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/926550:CLDAP_RS18175 ^@ http://purl.uniprot.org/uniprot/I0I8U2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/926550:CLDAP_RS16090 ^@ http://purl.uniprot.org/uniprot/I0I7L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS02770 ^@ http://purl.uniprot.org/uniprot/I0I001 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/926550:CLDAP_RS18265 ^@ http://purl.uniprot.org/uniprot/I0I8W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS12240 ^@ http://purl.uniprot.org/uniprot/I0I5D3 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/926550:CLDAP_RS04375 ^@ http://purl.uniprot.org/uniprot/I0I0W9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS10305 ^@ http://purl.uniprot.org/uniprot/I0I489 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/926550:CLDAP_RS13580 ^@ http://purl.uniprot.org/uniprot/I0I651 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS03505 ^@ http://purl.uniprot.org/uniprot/I0I0E6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/926550:CLDAP_RS02075 ^@ http://purl.uniprot.org/uniprot/I0I2N2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/926550:CLDAP_RS06160 ^@ http://purl.uniprot.org/uniprot/I0I1W9 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm5 family.|||This subunit might be involved in maturation of a crRNA intermediate to its mature form. http://togogenome.org/gene/926550:CLDAP_RS21160 ^@ http://purl.uniprot.org/uniprot/I0I3S1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/926550:CLDAP_RS21280 ^@ http://purl.uniprot.org/uniprot/I0I509 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/926550:CLDAP_RS02465 ^@ http://purl.uniprot.org/uniprot/I0HZU1 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/926550:CLDAP_RS18365 ^@ http://purl.uniprot.org/uniprot/I0I8Y0 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/926550:CLDAP_RS00490 ^@ http://purl.uniprot.org/uniprot/I0HYQ0 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/926550:CLDAP_RS00410 ^@ http://purl.uniprot.org/uniprot/I0HYN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS01750 ^@ http://purl.uniprot.org/uniprot/I0HZE9 ^@ Cofactor|||Similarity ^@ Belongs to the arginase family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/926550:CLDAP_RS08545 ^@ http://purl.uniprot.org/uniprot/I0I380 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/926550:CLDAP_RS05745 ^@ http://purl.uniprot.org/uniprot/I0I1N8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/926550:CLDAP_RS07935 ^@ http://purl.uniprot.org/uniprot/I0I2V6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS05700 ^@ http://purl.uniprot.org/uniprot/I0I1M9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell inner membrane|||Probably interacts with PlsX. http://togogenome.org/gene/926550:CLDAP_RS19865 ^@ http://purl.uniprot.org/uniprot/I0I9T7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/926550:CLDAP_RS06035 ^@ http://purl.uniprot.org/uniprot/I0I1U6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS20170 ^@ http://purl.uniprot.org/uniprot/I0I9Z8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS19315 ^@ http://purl.uniprot.org/uniprot/I0I9H1 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/926550:CLDAP_RS00970 ^@ http://purl.uniprot.org/uniprot/I0HYZ3 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/926550:CLDAP_RS04430 ^@ http://purl.uniprot.org/uniprot/I0I0Y0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell inner membrane|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/926550:CLDAP_RS20205 ^@ http://purl.uniprot.org/uniprot/I0IA06 ^@ Similarity ^@ Belongs to the aldolase LacD family. http://togogenome.org/gene/926550:CLDAP_RS02055 ^@ http://purl.uniprot.org/uniprot/I0HZL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/926550:CLDAP_RS01150 ^@ http://purl.uniprot.org/uniprot/I0HZ31 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS14045 ^@ http://purl.uniprot.org/uniprot/I0I6E6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS18070 ^@ http://purl.uniprot.org/uniprot/I0I8S0 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/926550:CLDAP_RS19190 ^@ http://purl.uniprot.org/uniprot/I0I9E7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/926550:CLDAP_RS23630 ^@ http://purl.uniprot.org/uniprot/I0I9C1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/926550:CLDAP_RS21000 ^@ http://purl.uniprot.org/uniprot/I0I254 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS03500 ^@ http://purl.uniprot.org/uniprot/I0I0E5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/926550:CLDAP_RS11330 ^@ http://purl.uniprot.org/uniprot/I0I4U7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS04515 ^@ http://purl.uniprot.org/uniprot/I0I0Z7 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/926550:CLDAP_RS06960 ^@ http://purl.uniprot.org/uniprot/I0I2C3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS10750 ^@ http://purl.uniprot.org/uniprot/I0I4H8 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/926550:CLDAP_RS06115 ^@ http://purl.uniprot.org/uniprot/I0I1W0 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/926550:CLDAP_RS17575 ^@ http://purl.uniprot.org/uniprot/I0I8H3 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/926550:CLDAP_RS14560 ^@ http://purl.uniprot.org/uniprot/I0I6Q6 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/926550:CLDAP_RS02035 ^@ http://purl.uniprot.org/uniprot/I0HZK6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/926550:CLDAP_RS04380 ^@ http://purl.uniprot.org/uniprot/I0I0X0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926550:CLDAP_RS17665 ^@ http://purl.uniprot.org/uniprot/I0I8J0 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/926550:CLDAP_RS20430 ^@ http://purl.uniprot.org/uniprot/I0IA51 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/926550:CLDAP_RS10035 ^@ http://purl.uniprot.org/uniprot/I0I435 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS02775 ^@ http://purl.uniprot.org/uniprot/I0I002 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS06250 ^@ http://purl.uniprot.org/uniprot/I0I1Y8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/926550:CLDAP_RS09690 ^@ http://purl.uniprot.org/uniprot/I0I3W3 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/926550:CLDAP_RS17605 ^@ http://purl.uniprot.org/uniprot/I0I8H9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS11525 ^@ http://purl.uniprot.org/uniprot/I0I4Y6 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS00985 ^@ http://purl.uniprot.org/uniprot/I0HYZ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS11140 ^@ http://purl.uniprot.org/uniprot/I0I4R0 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. http://togogenome.org/gene/926550:CLDAP_RS04000 ^@ http://purl.uniprot.org/uniprot/I0I0P6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS14315 ^@ http://purl.uniprot.org/uniprot/I0I6K5 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/926550:CLDAP_RS17550 ^@ http://purl.uniprot.org/uniprot/I0I8G8 ^@ Similarity ^@ Belongs to the spermidine/spermine synthase family. http://togogenome.org/gene/926550:CLDAP_RS06085 ^@ http://purl.uniprot.org/uniprot/I0I1V5 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/926550:CLDAP_RS06345 ^@ http://purl.uniprot.org/uniprot/I0I207 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS12080 ^@ http://purl.uniprot.org/uniprot/I0I597 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS06000 ^@ http://purl.uniprot.org/uniprot/I0I1T8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS21385 ^@ http://purl.uniprot.org/uniprot/I0I6B0 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/926550:CLDAP_RS10155 ^@ http://purl.uniprot.org/uniprot/I0I458 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/926550:CLDAP_RS18880 ^@ http://purl.uniprot.org/uniprot/I0I985 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/926550:CLDAP_RS18480 ^@ http://purl.uniprot.org/uniprot/I0I904 ^@ Similarity ^@ Belongs to the antibiotic N-acetyltransferase family. http://togogenome.org/gene/926550:CLDAP_RS01770 ^@ http://purl.uniprot.org/uniprot/I0HZF3 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/926550:CLDAP_RS15280 ^@ http://purl.uniprot.org/uniprot/I0I752 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/926550:CLDAP_RS12495 ^@ http://purl.uniprot.org/uniprot/I0I5I6 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/926550:CLDAP_RS15105 ^@ http://purl.uniprot.org/uniprot/I0I717 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/926550:CLDAP_RS12635 ^@ http://purl.uniprot.org/uniprot/I0I5L3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS16455 ^@ http://purl.uniprot.org/uniprot/I0I7U0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS12465 ^@ http://purl.uniprot.org/uniprot/I0I5I0 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS09800 ^@ http://purl.uniprot.org/uniprot/I0I3Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS10290 ^@ http://purl.uniprot.org/uniprot/I0I486 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/926550:CLDAP_RS10375 ^@ http://purl.uniprot.org/uniprot/I0I4A3 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/926550:CLDAP_RS04135 ^@ http://purl.uniprot.org/uniprot/I0I0S3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/926550:CLDAP_RS14190 ^@ http://purl.uniprot.org/uniprot/I0I6H9 ^@ Function|||Similarity ^@ Belongs to the GTP cyclohydrolase IV family.|||Converts GTP to 7,8-dihydroneopterin triphosphate. http://togogenome.org/gene/926550:CLDAP_RS16280 ^@ http://purl.uniprot.org/uniprot/I0I7Q3 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/926550:CLDAP_RS05395 ^@ http://purl.uniprot.org/uniprot/I0I1G9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/926550:CLDAP_RS17025 ^@ http://purl.uniprot.org/uniprot/I0I861 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/926550:CLDAP_RS17340 ^@ http://purl.uniprot.org/uniprot/I0I8C2 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/926550:CLDAP_RS03800 ^@ http://purl.uniprot.org/uniprot/I0I0K5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/926550:CLDAP_RS19975 ^@ http://purl.uniprot.org/uniprot/I0I9V9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/926550:CLDAP_RS13515 ^@ http://purl.uniprot.org/uniprot/I0I638 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS02420 ^@ http://purl.uniprot.org/uniprot/I0HZT2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/926550:CLDAP_RS03730 ^@ http://purl.uniprot.org/uniprot/I0I0J0 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/926550:CLDAP_RS14660 ^@ http://purl.uniprot.org/uniprot/I0I6S6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS15680 ^@ http://purl.uniprot.org/uniprot/I0I7D1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/926550:CLDAP_RS01855 ^@ http://purl.uniprot.org/uniprot/I0HZG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/926550:CLDAP_RS15690 ^@ http://purl.uniprot.org/uniprot/I0I7D3 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/926550:CLDAP_RS01295 ^@ http://purl.uniprot.org/uniprot/I0HZ58 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/926550:CLDAP_RS15325 ^@ http://purl.uniprot.org/uniprot/I0I761 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell inner membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/926550:CLDAP_RS10045 ^@ http://purl.uniprot.org/uniprot/I0I437 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/926550:CLDAP_RS16785 ^@ http://purl.uniprot.org/uniprot/I0I812 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/926550:CLDAP_RS08760 ^@ http://purl.uniprot.org/uniprot/I0I3C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS15370 ^@ http://purl.uniprot.org/uniprot/I0I770 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/926550:CLDAP_RS21945 ^@ http://purl.uniprot.org/uniprot/I0I5T0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/926550:CLDAP_RS07575 ^@ http://purl.uniprot.org/uniprot/I0I2N6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/926550:CLDAP_RS18925 ^@ http://purl.uniprot.org/uniprot/I0I994 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/926550:CLDAP_RS13340 ^@ http://purl.uniprot.org/uniprot/I0I602 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS10625 ^@ http://purl.uniprot.org/uniprot/I0I4F2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/926550:CLDAP_RS18865 ^@ http://purl.uniprot.org/uniprot/I0I982 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/926550:CLDAP_RS06505 ^@ http://purl.uniprot.org/uniprot/I0I240 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS20060 ^@ http://purl.uniprot.org/uniprot/I0I9X7 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/926550:CLDAP_RS08880 ^@ http://purl.uniprot.org/uniprot/I0I3E9 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/926550:CLDAP_RS15490 ^@ http://purl.uniprot.org/uniprot/I0I794 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/926550:CLDAP_RS01425 ^@ http://purl.uniprot.org/uniprot/I0HZ83 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/926550:CLDAP_RS07080 ^@ http://purl.uniprot.org/uniprot/I0I2E4 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS01470 ^@ http://purl.uniprot.org/uniprot/I0HZ92 ^@ Similarity ^@ Belongs to the pyruvate kinase family.|||In the C-terminal section; belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/926550:CLDAP_RS06180 ^@ http://purl.uniprot.org/uniprot/I0I1X3 ^@ Similarity ^@ Belongs to the CRISPR-associated Cas10/Csm1 family. http://togogenome.org/gene/926550:CLDAP_RS01655 ^@ http://purl.uniprot.org/uniprot/I0HZC9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/926550:CLDAP_RS07795 ^@ http://purl.uniprot.org/uniprot/I0I2S9 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/926550:CLDAP_RS06130 ^@ http://purl.uniprot.org/uniprot/I0I1W3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/926550:CLDAP_RS04960 ^@ http://purl.uniprot.org/uniprot/I0I186 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/926550:CLDAP_RS14600 ^@ http://purl.uniprot.org/uniprot/I0I6R3 ^@ Function ^@ Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. http://togogenome.org/gene/926550:CLDAP_RS18820 ^@ http://purl.uniprot.org/uniprot/I0I973 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/926550:CLDAP_RS16230 ^@ http://purl.uniprot.org/uniprot/I0I7P6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS09580 ^@ http://purl.uniprot.org/uniprot/I0I3T9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS01810 ^@ http://purl.uniprot.org/uniprot/I0HZG0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS00745 ^@ http://purl.uniprot.org/uniprot/I0HYU8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/926550:CLDAP_RS08135 ^@ http://purl.uniprot.org/uniprot/I0I2Z5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS02135 ^@ http://purl.uniprot.org/uniprot/I0HZM6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/926550:CLDAP_RS15545 ^@ http://purl.uniprot.org/uniprot/I0I7A5 ^@ Cofactor ^@ Binds 2 magnesium ions per subunit. http://togogenome.org/gene/926550:CLDAP_RS13240 ^@ http://purl.uniprot.org/uniprot/I0I5Y2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.|||Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS16870 ^@ http://purl.uniprot.org/uniprot/I0I829 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS20415 ^@ http://purl.uniprot.org/uniprot/I0IA48 ^@ Similarity ^@ Belongs to the 4-hydroxy-2-oxovalerate aldolase family. http://togogenome.org/gene/926550:CLDAP_RS15535 ^@ http://purl.uniprot.org/uniprot/I0I7A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS13005 ^@ http://purl.uniprot.org/uniprot/I0I5T5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS01055 ^@ http://purl.uniprot.org/uniprot/I0HZ11 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/926550:CLDAP_RS02545 ^@ http://purl.uniprot.org/uniprot/I0HZV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/926550:CLDAP_RS07620 ^@ http://purl.uniprot.org/uniprot/I0I2P5 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/926550:CLDAP_RS01100 ^@ http://purl.uniprot.org/uniprot/I0HZ21 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS15640 ^@ http://purl.uniprot.org/uniprot/I0I7C3 ^@ Similarity ^@ Belongs to the UPF0166 family. http://togogenome.org/gene/926550:CLDAP_RS02385 ^@ http://purl.uniprot.org/uniprot/I0HZS4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/926550:CLDAP_RS07910 ^@ http://purl.uniprot.org/uniprot/I0I2V1 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/926550:CLDAP_RS08050 ^@ http://purl.uniprot.org/uniprot/I0I2X8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS07550 ^@ http://purl.uniprot.org/uniprot/I0I2N2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/926550:CLDAP_RS08970 ^@ http://purl.uniprot.org/uniprot/I0I3G6 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/926550:CLDAP_RS01480 ^@ http://purl.uniprot.org/uniprot/I0HZ94 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS01585 ^@ http://purl.uniprot.org/uniprot/I0HZB5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS08395 ^@ http://purl.uniprot.org/uniprot/I0I349 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS13370 ^@ http://purl.uniprot.org/uniprot/I0I608 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS01935 ^@ http://purl.uniprot.org/uniprot/I0HZI5 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/926550:CLDAP_RS07765 ^@ http://purl.uniprot.org/uniprot/I0I2S4 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/926550:CLDAP_RS05605 ^@ http://purl.uniprot.org/uniprot/I0I1L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS16240 ^@ http://purl.uniprot.org/uniprot/I0I7P8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS14595 ^@ http://purl.uniprot.org/uniprot/I0I6R2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS08835 ^@ http://purl.uniprot.org/uniprot/I0I3E0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/926550:CLDAP_RS19430 ^@ http://purl.uniprot.org/uniprot/I0I9J7 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/926550:CLDAP_RS02405 ^@ http://purl.uniprot.org/uniprot/I0HZS9 ^@ Function|||Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.|||Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway. http://togogenome.org/gene/926550:CLDAP_RS07870 ^@ http://purl.uniprot.org/uniprot/I0I2U3 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/926550:CLDAP_RS06770 ^@ http://purl.uniprot.org/uniprot/I0I290 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS19855 ^@ http://purl.uniprot.org/uniprot/I0I9T5 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/926550:CLDAP_RS05630 ^@ http://purl.uniprot.org/uniprot/I0I1L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS09980 ^@ http://purl.uniprot.org/uniprot/I0I424 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/926550:CLDAP_RS16950 ^@ http://purl.uniprot.org/uniprot/I0I845 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS20235 ^@ http://purl.uniprot.org/uniprot/I0IA12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS04365 ^@ http://purl.uniprot.org/uniprot/I0I0W7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926550:CLDAP_RS17630 ^@ http://purl.uniprot.org/uniprot/I0I8I3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS12390 ^@ http://purl.uniprot.org/uniprot/I0I5G4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS12470 ^@ http://purl.uniprot.org/uniprot/I0I5I1 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/926550:CLDAP_RS19820 ^@ http://purl.uniprot.org/uniprot/I0I9S8 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/926550:CLDAP_RS10885 ^@ http://purl.uniprot.org/uniprot/I0I4K6 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/926550:CLDAP_RS11405 ^@ http://purl.uniprot.org/uniprot/I0I4W2 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/926550:CLDAP_RS11645 ^@ http://purl.uniprot.org/uniprot/I0I511 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS03330 ^@ http://purl.uniprot.org/uniprot/I0I0B1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/926550:CLDAP_RS17335 ^@ http://purl.uniprot.org/uniprot/I0I8C1 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926550:CLDAP_RS07275 ^@ http://purl.uniprot.org/uniprot/I0I2I2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS09975 ^@ http://purl.uniprot.org/uniprot/I0I423 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS06665 ^@ http://purl.uniprot.org/uniprot/I0I272 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS06455 ^@ http://purl.uniprot.org/uniprot/I0I230 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS05490 ^@ http://purl.uniprot.org/uniprot/I0I1I7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS03225 ^@ http://purl.uniprot.org/uniprot/I0I090 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/926550:CLDAP_RS15940 ^@ http://purl.uniprot.org/uniprot/I0I7I4 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/926550:CLDAP_RS15085 ^@ http://purl.uniprot.org/uniprot/I0I713 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/926550:CLDAP_RS09680 ^@ http://purl.uniprot.org/uniprot/I0I3W1 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/926550:CLDAP_RS02475 ^@ http://purl.uniprot.org/uniprot/I0HZU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial glucokinase family.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS21925 ^@ http://purl.uniprot.org/uniprot/I0I3X2 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/926550:CLDAP_RS09550 ^@ http://purl.uniprot.org/uniprot/I0I3T2 ^@ Similarity ^@ Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. http://togogenome.org/gene/926550:CLDAP_RS13865 ^@ http://purl.uniprot.org/uniprot/I0I6A9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS12515 ^@ http://purl.uniprot.org/uniprot/I0I5J0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS04225 ^@ http://purl.uniprot.org/uniprot/I0I0U0 ^@ Similarity ^@ Belongs to the FtsK/SpoIIIE/SftA family. http://togogenome.org/gene/926550:CLDAP_RS04530 ^@ http://purl.uniprot.org/uniprot/I0I100 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/926550:CLDAP_RS01905 ^@ http://purl.uniprot.org/uniprot/I0HZH9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/926550:CLDAP_RS12420 ^@ http://purl.uniprot.org/uniprot/I0I5H1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/926550:CLDAP_RS19280 ^@ http://purl.uniprot.org/uniprot/I0I9G4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS19485 ^@ http://purl.uniprot.org/uniprot/I0I9L1 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/926550:CLDAP_RS12375 ^@ http://purl.uniprot.org/uniprot/I0I5G1 ^@ Similarity ^@ Belongs to the UPF0162 family. http://togogenome.org/gene/926550:CLDAP_RS14700 ^@ http://purl.uniprot.org/uniprot/I0I6T4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/926550:CLDAP_RS13795 ^@ http://purl.uniprot.org/uniprot/I0I696 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/926550:CLDAP_RS21575 ^@ http://purl.uniprot.org/uniprot/I0I811 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/926550:CLDAP_RS08265 ^@ http://purl.uniprot.org/uniprot/I0I323 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS10065 ^@ http://purl.uniprot.org/uniprot/I0I439 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/926550:CLDAP_RS18600 ^@ http://purl.uniprot.org/uniprot/I0I930 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/926550:CLDAP_RS14575 ^@ http://purl.uniprot.org/uniprot/I0I6Q9 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/926550:CLDAP_RS19665 ^@ http://purl.uniprot.org/uniprot/I0I9P9 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/926550:CLDAP_RS10445 ^@ http://purl.uniprot.org/uniprot/I0I4B7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/926550:CLDAP_RS06880 ^@ http://purl.uniprot.org/uniprot/I0I2B3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS10825 ^@ http://purl.uniprot.org/uniprot/I0I4J3 ^@ Similarity ^@ Belongs to the lycopene cyclase family. http://togogenome.org/gene/926550:CLDAP_RS03140 ^@ http://purl.uniprot.org/uniprot/I0I073 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/926550:CLDAP_RS15040 ^@ http://purl.uniprot.org/uniprot/I0I704 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS06485 ^@ http://purl.uniprot.org/uniprot/I0I236 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/926550:CLDAP_RS11530 ^@ http://purl.uniprot.org/uniprot/I0I4Y7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family. MenD subfamily.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS02685 ^@ http://purl.uniprot.org/uniprot/I0HZY4 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS15750 ^@ http://purl.uniprot.org/uniprot/I0I7E5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/926550:CLDAP_RS09235 ^@ http://purl.uniprot.org/uniprot/I0I3M1 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/926550:CLDAP_RS17950 ^@ http://purl.uniprot.org/uniprot/I0I8P6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS11745 ^@ http://purl.uniprot.org/uniprot/I0I531 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS17485 ^@ http://purl.uniprot.org/uniprot/I0I8F4 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/926550:CLDAP_RS02310 ^@ http://purl.uniprot.org/uniprot/I0HZQ9 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/926550:CLDAP_RS05335 ^@ http://purl.uniprot.org/uniprot/I0I1F8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS16315 ^@ http://purl.uniprot.org/uniprot/I0I7R0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/926550:CLDAP_RS16330 ^@ http://purl.uniprot.org/uniprot/I0I7R3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS03390 ^@ http://purl.uniprot.org/uniprot/I0I0C3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/926550:CLDAP_RS18945 ^@ http://purl.uniprot.org/uniprot/I0I998 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS21725 ^@ http://purl.uniprot.org/uniprot/I0I991 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS02430 ^@ http://purl.uniprot.org/uniprot/I0HZT4 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/926550:CLDAP_RS12595 ^@ http://purl.uniprot.org/uniprot/I0I5K6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS15605 ^@ http://purl.uniprot.org/uniprot/I0I7B7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/926550:CLDAP_RS03260 ^@ http://purl.uniprot.org/uniprot/I0I098 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/926550:CLDAP_RS10930 ^@ http://purl.uniprot.org/uniprot/I0I4L5 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/926550:CLDAP_RS00645 ^@ http://purl.uniprot.org/uniprot/I0HYT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS02610 ^@ http://purl.uniprot.org/uniprot/I0HZW9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS18450 ^@ http://purl.uniprot.org/uniprot/I0I8Z7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS18980 ^@ http://purl.uniprot.org/uniprot/I0I9A5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell inner membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/926550:CLDAP_RS02670 ^@ http://purl.uniprot.org/uniprot/I0HZY1 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/926550:CLDAP_RS00795 ^@ http://purl.uniprot.org/uniprot/I0HYV8 ^@ Similarity ^@ Belongs to the Rpn/YhgA-like nuclease family. http://togogenome.org/gene/926550:CLDAP_RS02715 ^@ http://purl.uniprot.org/uniprot/I0HZZ0 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/926550:CLDAP_RS16750 ^@ http://purl.uniprot.org/uniprot/I0I805 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/926550:CLDAP_RS01900 ^@ http://purl.uniprot.org/uniprot/I0HZH8 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/926550:CLDAP_RS11185 ^@ http://purl.uniprot.org/uniprot/I0I4R9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS02205 ^@ http://purl.uniprot.org/uniprot/I0HZP1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/926550:CLDAP_RS08910 ^@ http://purl.uniprot.org/uniprot/I0I3F5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS09935 ^@ http://purl.uniprot.org/uniprot/I0I415 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/926550:CLDAP_RS10455 ^@ http://purl.uniprot.org/uniprot/I0I4B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS08350 ^@ http://purl.uniprot.org/uniprot/I0I340 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/926550:CLDAP_RS11270 ^@ http://purl.uniprot.org/uniprot/I0I4T6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS19725 ^@ http://purl.uniprot.org/uniprot/I0I9Q9 ^@ Cofactor ^@ Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/926550:CLDAP_RS01435 ^@ http://purl.uniprot.org/uniprot/I0HZ85 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/926550:CLDAP_RS18475 ^@ http://purl.uniprot.org/uniprot/I0I903 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Arsenite methyltransferase family. http://togogenome.org/gene/926550:CLDAP_RS01610 ^@ http://purl.uniprot.org/uniprot/I0HZB9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/926550:CLDAP_RS15555 ^@ http://purl.uniprot.org/uniprot/I0I7A7 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/926550:CLDAP_RS12065 ^@ http://purl.uniprot.org/uniprot/I0I594 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/926550:CLDAP_RS14770 ^@ http://purl.uniprot.org/uniprot/I0I6U9 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/926550:CLDAP_RS03475 ^@ http://purl.uniprot.org/uniprot/I0I0E0 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/926550:CLDAP_RS10325 ^@ http://purl.uniprot.org/uniprot/I0I493 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/926550:CLDAP_RS21320 ^@ http://purl.uniprot.org/uniprot/I0I5I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS00165 ^@ http://purl.uniprot.org/uniprot/I0HYI5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/926550:CLDAP_RS01330 ^@ http://purl.uniprot.org/uniprot/I0HZ64 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/926550:CLDAP_RS09825 ^@ http://purl.uniprot.org/uniprot/I0I3Z2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS16915 ^@ http://purl.uniprot.org/uniprot/I0I838 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/926550:CLDAP_RS13635 ^@ http://purl.uniprot.org/uniprot/I0I662 ^@ Similarity ^@ Belongs to the BtpA family. http://togogenome.org/gene/926550:CLDAP_RS02535 ^@ http://purl.uniprot.org/uniprot/I0HZV5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS19500 ^@ http://purl.uniprot.org/uniprot/I0I9L4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS13810 ^@ http://purl.uniprot.org/uniprot/I0I699 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS07735 ^@ http://purl.uniprot.org/uniprot/I0I2R7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS03980 ^@ http://purl.uniprot.org/uniprot/I0I0P2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS03635 ^@ http://purl.uniprot.org/uniprot/I0I0H1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS10575 ^@ http://purl.uniprot.org/uniprot/I0I4E2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS21665 ^@ http://purl.uniprot.org/uniprot/I0I8L4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS11385 ^@ http://purl.uniprot.org/uniprot/I0I4V8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS00750 ^@ http://purl.uniprot.org/uniprot/I0HYU9 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS05655 ^@ http://purl.uniprot.org/uniprot/I0I1M0 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/926550:CLDAP_RS14750 ^@ http://purl.uniprot.org/uniprot/I0I6U5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS13950 ^@ http://purl.uniprot.org/uniprot/I0I6C6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS00255 ^@ http://purl.uniprot.org/uniprot/I0HYK3 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/926550:CLDAP_RS23680 ^@ http://purl.uniprot.org/uniprot/I0I2J2 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/926550:CLDAP_RS09125 ^@ http://purl.uniprot.org/uniprot/I0I3K0 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/926550:CLDAP_RS12800 ^@ http://purl.uniprot.org/uniprot/I0I5P5 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/926550:CLDAP_RS15250 ^@ http://purl.uniprot.org/uniprot/I0I746 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/926550:CLDAP_RS06550 ^@ http://purl.uniprot.org/uniprot/I0I249 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CitM (TC 2.A.11) transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS06590 ^@ http://purl.uniprot.org/uniprot/I0I257 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS08755 ^@ http://purl.uniprot.org/uniprot/I0I3C4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS16955 ^@ http://purl.uniprot.org/uniprot/I0I846 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudC subfamily.|||Binds 1 zinc ion per subunit.|||Divalent metal cations. Mg(2+) or Mn(2+).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates. http://togogenome.org/gene/926550:CLDAP_RS13195 ^@ http://purl.uniprot.org/uniprot/I0I5X3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system. http://togogenome.org/gene/926550:CLDAP_RS05670 ^@ http://purl.uniprot.org/uniprot/I0I1M3 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/926550:CLDAP_RS18185 ^@ http://purl.uniprot.org/uniprot/I0I8U4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS12050 ^@ http://purl.uniprot.org/uniprot/I0I591 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/926550:CLDAP_RS02320 ^@ http://purl.uniprot.org/uniprot/I0HZR1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS05650 ^@ http://purl.uniprot.org/uniprot/I0I1L9 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/926550:CLDAP_RS13690 ^@ http://purl.uniprot.org/uniprot/I0I674 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/926550:CLDAP_RS20250 ^@ http://purl.uniprot.org/uniprot/I0IA15 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/926550:CLDAP_RS02820 ^@ http://purl.uniprot.org/uniprot/I0I010 ^@ Similarity ^@ Belongs to the isopentenyl phosphate kinase family. http://togogenome.org/gene/926550:CLDAP_RS10070 ^@ http://purl.uniprot.org/uniprot/I0I440 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/926550:CLDAP_RS11260 ^@ http://purl.uniprot.org/uniprot/I0I4T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS06365 ^@ http://purl.uniprot.org/uniprot/I0I211 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/926550:CLDAP_RS07580 ^@ http://purl.uniprot.org/uniprot/I0I2N7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/926550:CLDAP_RS10350 ^@ http://purl.uniprot.org/uniprot/I0I498 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably interacts with PlsX. http://togogenome.org/gene/926550:CLDAP_RS23290 ^@ http://purl.uniprot.org/uniprot/I0I567 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. http://togogenome.org/gene/926550:CLDAP_RS18630 ^@ http://purl.uniprot.org/uniprot/I0I936 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/926550:CLDAP_RS04535 ^@ http://purl.uniprot.org/uniprot/I0I101 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS19970 ^@ http://purl.uniprot.org/uniprot/I0I9V8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS03835 ^@ http://purl.uniprot.org/uniprot/I0I0L3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS02570 ^@ http://purl.uniprot.org/uniprot/I0HZW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS15755 ^@ http://purl.uniprot.org/uniprot/I0I7E6 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/926550:CLDAP_RS07015 ^@ http://purl.uniprot.org/uniprot/I0I2D2 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926550:CLDAP_RS09675 ^@ http://purl.uniprot.org/uniprot/I0I3W0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS20040 ^@ http://purl.uniprot.org/uniprot/I0I9X2 ^@ Similarity ^@ Belongs to the UPF0175 family. http://togogenome.org/gene/926550:CLDAP_RS18645 ^@ http://purl.uniprot.org/uniprot/I0I939 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS01975 ^@ http://purl.uniprot.org/uniprot/I0HZJ4 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/926550:CLDAP_RS02140 ^@ http://purl.uniprot.org/uniprot/I0HZM7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/926550:CLDAP_RS17685 ^@ http://purl.uniprot.org/uniprot/I0I8J4 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS11820 ^@ http://purl.uniprot.org/uniprot/I0I545 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS05795 ^@ http://purl.uniprot.org/uniprot/I0I1P8 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/926550:CLDAP_RS19530 ^@ http://purl.uniprot.org/uniprot/I0I9M1 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS00310 ^@ http://purl.uniprot.org/uniprot/I0HYL4 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS02935 ^@ http://purl.uniprot.org/uniprot/I0I033 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS09710 ^@ http://purl.uniprot.org/uniprot/I0I3W7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III. http://togogenome.org/gene/926550:CLDAP_RS13920 ^@ http://purl.uniprot.org/uniprot/I0I6C0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS04800 ^@ http://purl.uniprot.org/uniprot/I0I156 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/926550:CLDAP_RS01960 ^@ http://purl.uniprot.org/uniprot/I0HZJ1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/926550:CLDAP_RS15900 ^@ http://purl.uniprot.org/uniprot/I0I7H5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS08735 ^@ http://purl.uniprot.org/uniprot/I0I3B9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/926550:CLDAP_RS07225 ^@ http://purl.uniprot.org/uniprot/I0I2H2 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/926550:CLDAP_RS19980 ^@ http://purl.uniprot.org/uniprot/I0I9W0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/926550:CLDAP_RS16545 ^@ http://purl.uniprot.org/uniprot/I0I7V9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRISPR system Cmr5 family.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS21625 ^@ http://purl.uniprot.org/uniprot/I0I8F5 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/926550:CLDAP_RS12060 ^@ http://purl.uniprot.org/uniprot/I0I593 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/926550:CLDAP_RS17020 ^@ http://purl.uniprot.org/uniprot/I0I860 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS13550 ^@ http://purl.uniprot.org/uniprot/I0I645 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS06090 ^@ http://purl.uniprot.org/uniprot/I0I1V6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/926550:CLDAP_RS08160 ^@ http://purl.uniprot.org/uniprot/I0I301 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/926550:CLDAP_RS01980 ^@ http://purl.uniprot.org/uniprot/I0HZJ5 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/926550:CLDAP_RS08470 ^@ http://purl.uniprot.org/uniprot/I0I365 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/926550:CLDAP_RS02025 ^@ http://purl.uniprot.org/uniprot/I0HZK4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/926550:CLDAP_RS04440 ^@ http://purl.uniprot.org/uniprot/I0I0Y2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926550:CLDAP_RS05480 ^@ http://purl.uniprot.org/uniprot/I0I1I5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS08525 ^@ http://purl.uniprot.org/uniprot/I0I376 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/926550:CLDAP_RS19030 ^@ http://purl.uniprot.org/uniprot/I0I9B5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS01915 ^@ http://purl.uniprot.org/uniprot/I0HZI1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/926550:CLDAP_RS11295 ^@ http://purl.uniprot.org/uniprot/I0I4U0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/926550:CLDAP_RS04400 ^@ http://purl.uniprot.org/uniprot/I0I0X4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926550:CLDAP_RS18210 ^@ http://purl.uniprot.org/uniprot/I0I8U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS00200 ^@ http://purl.uniprot.org/uniprot/I0HYJ2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/926550:CLDAP_RS21495 ^@ http://purl.uniprot.org/uniprot/I0I6Y6 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/926550:CLDAP_RS15420 ^@ http://purl.uniprot.org/uniprot/I0I780 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS02425 ^@ http://purl.uniprot.org/uniprot/I0HZT3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/926550:CLDAP_RS05930 ^@ http://purl.uniprot.org/uniprot/I0I1S4 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/926550:CLDAP_RS19685 ^@ http://purl.uniprot.org/uniprot/I0I9Q3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/926550:CLDAP_RS14540 ^@ http://purl.uniprot.org/uniprot/I0I6Q2 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/926550:CLDAP_RS14620 ^@ http://purl.uniprot.org/uniprot/I0I6R7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS04150 ^@ http://purl.uniprot.org/uniprot/I0I0S5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS00125 ^@ http://purl.uniprot.org/uniprot/I0HYH7 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926550:CLDAP_RS04175 ^@ http://purl.uniprot.org/uniprot/I0I0T0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.|||Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS15100 ^@ http://purl.uniprot.org/uniprot/I0I716 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/926550:CLDAP_RS16595 ^@ http://purl.uniprot.org/uniprot/I0I7X1 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/926550:CLDAP_RS08870 ^@ http://purl.uniprot.org/uniprot/I0I3E7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/926550:CLDAP_RS18130 ^@ http://purl.uniprot.org/uniprot/I0I8T2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS09295 ^@ http://purl.uniprot.org/uniprot/I0I3N1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS14280 ^@ http://purl.uniprot.org/uniprot/I0I6J8 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/926550:CLDAP_RS06475 ^@ http://purl.uniprot.org/uniprot/I0I234 ^@ Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/926550:CLDAP_RS02890 ^@ http://purl.uniprot.org/uniprot/I0I024 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS17545 ^@ http://purl.uniprot.org/uniprot/I0I8G7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS02555 ^@ http://purl.uniprot.org/uniprot/I0HZV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/926550:CLDAP_RS00640 ^@ http://purl.uniprot.org/uniprot/I0HYS9 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/926550:CLDAP_RS09020 ^@ http://purl.uniprot.org/uniprot/I0I3H7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/926550:CLDAP_RS05865 ^@ http://purl.uniprot.org/uniprot/I0I1R2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrC/TusE family.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS11770 ^@ http://purl.uniprot.org/uniprot/I0I536 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/926550:CLDAP_RS08805 ^@ http://purl.uniprot.org/uniprot/I0I3D4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS14890 ^@ http://purl.uniprot.org/uniprot/I0I6X3 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/926550:CLDAP_RS17415 ^@ http://purl.uniprot.org/uniprot/I0I8D8 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS19675 ^@ http://purl.uniprot.org/uniprot/I0I9Q1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS07675 ^@ http://purl.uniprot.org/uniprot/I0I2Q6 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MsrP family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.|||Periplasm|||Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. http://togogenome.org/gene/926550:CLDAP_RS02745 ^@ http://purl.uniprot.org/uniprot/I0HZZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS04570 ^@ http://purl.uniprot.org/uniprot/I0I108 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/926550:CLDAP_RS04490 ^@ http://purl.uniprot.org/uniprot/I0I0Z2 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS06525 ^@ http://purl.uniprot.org/uniprot/I0I244 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS00825 ^@ http://purl.uniprot.org/uniprot/I0HYW5 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/926550:CLDAP_RS12025 ^@ http://purl.uniprot.org/uniprot/I0I586 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS07070 ^@ http://purl.uniprot.org/uniprot/I0I2E2 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/926550:CLDAP_RS01680 ^@ http://purl.uniprot.org/uniprot/I0HZD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS12280 ^@ http://purl.uniprot.org/uniprot/I0I5E2 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/926550:CLDAP_RS09630 ^@ http://purl.uniprot.org/uniprot/I0I3V0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/926550:CLDAP_RS05000 ^@ http://purl.uniprot.org/uniprot/I0I193 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/926550:CLDAP_RS01860 ^@ http://purl.uniprot.org/uniprot/I0HZH0 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS08390 ^@ http://purl.uniprot.org/uniprot/I0I348 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS04540 ^@ http://purl.uniprot.org/uniprot/I0I102 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS18485 ^@ http://purl.uniprot.org/uniprot/I0I905 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/926550:CLDAP_RS06545 ^@ http://purl.uniprot.org/uniprot/I0I248 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926550:CLDAP_RS11105 ^@ http://purl.uniprot.org/uniprot/I0I4Q3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS05740 ^@ http://purl.uniprot.org/uniprot/I0I1N7 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/926550:CLDAP_RS17965 ^@ http://purl.uniprot.org/uniprot/I0I8P9 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/926550:CLDAP_RS05485 ^@ http://purl.uniprot.org/uniprot/I0I1I6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS10150 ^@ http://purl.uniprot.org/uniprot/I0I457 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS05135 ^@ http://purl.uniprot.org/uniprot/I0I1C1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS18500 ^@ http://purl.uniprot.org/uniprot/I0I908 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/926550:CLDAP_RS12835 ^@ http://purl.uniprot.org/uniprot/I0I5Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS08140 ^@ http://purl.uniprot.org/uniprot/I0I2Z6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/926550:CLDAP_RS18440 ^@ http://purl.uniprot.org/uniprot/I0I8Z5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS11165 ^@ http://purl.uniprot.org/uniprot/I0I4R5 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/926550:CLDAP_RS17925 ^@ http://purl.uniprot.org/uniprot/I0I8P1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/926550:CLDAP_RS17700 ^@ http://purl.uniprot.org/uniprot/I0I8J7 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/926550:CLDAP_RS00655 ^@ http://purl.uniprot.org/uniprot/I0HYT2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/926550:CLDAP_RS15010 ^@ http://purl.uniprot.org/uniprot/I0I6Z7 ^@ Function ^@ Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. http://togogenome.org/gene/926550:CLDAP_RS02195 ^@ http://purl.uniprot.org/uniprot/I0HZN8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS14415 ^@ http://purl.uniprot.org/uniprot/I0I6M5 ^@ Similarity ^@ Belongs to the ycf81 family. http://togogenome.org/gene/926550:CLDAP_RS19325 ^@ http://purl.uniprot.org/uniprot/I0I9H3 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/926550:CLDAP_RS08495 ^@ http://purl.uniprot.org/uniprot/I0I370 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/926550:CLDAP_RS18370 ^@ http://purl.uniprot.org/uniprot/I0I8Y1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS11320 ^@ http://purl.uniprot.org/uniprot/I0I4U5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS15705 ^@ http://purl.uniprot.org/uniprot/I0I7D6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS20255 ^@ http://purl.uniprot.org/uniprot/I0IA16 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS08435 ^@ http://purl.uniprot.org/uniprot/I0I358 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/926550:CLDAP_RS10370 ^@ http://purl.uniprot.org/uniprot/I0I4A2 ^@ Similarity ^@ Belongs to the LarC family. http://togogenome.org/gene/926550:CLDAP_RS14400 ^@ http://purl.uniprot.org/uniprot/I0I6M2 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/926550:CLDAP_RS21165 ^@ http://purl.uniprot.org/uniprot/I0I3T8 ^@ Similarity ^@ Belongs to the pseudouridine synthase RluA family. http://togogenome.org/gene/926550:CLDAP_RS11975 ^@ http://purl.uniprot.org/uniprot/I0I577 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/926550:CLDAP_RS06815 ^@ http://purl.uniprot.org/uniprot/I0I299 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/926550:CLDAP_RS21265 ^@ http://purl.uniprot.org/uniprot/I0I4X1 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/926550:CLDAP_RS19095 ^@ http://purl.uniprot.org/uniprot/I0I9C8 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/926550:CLDAP_RS03415 ^@ http://purl.uniprot.org/uniprot/I0I0C8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS11280 ^@ http://purl.uniprot.org/uniprot/I0I4T8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS07305 ^@ http://purl.uniprot.org/uniprot/I0I2I9 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/926550:CLDAP_RS15345 ^@ http://purl.uniprot.org/uniprot/I0I765 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/926550:CLDAP_RS02825 ^@ http://purl.uniprot.org/uniprot/I0I011 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS06410 ^@ http://purl.uniprot.org/uniprot/I0I220 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/926550:CLDAP_RS08935 ^@ http://purl.uniprot.org/uniprot/I0I3F9 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS01970 ^@ http://purl.uniprot.org/uniprot/I0HZJ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/926550:CLDAP_RS15400 ^@ http://purl.uniprot.org/uniprot/I0I776 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS10515 ^@ http://purl.uniprot.org/uniprot/I0I4D1 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/926550:CLDAP_RS11155 ^@ http://purl.uniprot.org/uniprot/I0I4R3 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS00145 ^@ http://purl.uniprot.org/uniprot/I0HYI1 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/926550:CLDAP_RS14440 ^@ http://purl.uniprot.org/uniprot/I0I6N1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS06535 ^@ http://purl.uniprot.org/uniprot/I0I246 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/926550:CLDAP_RS10615 ^@ http://purl.uniprot.org/uniprot/I0I4F0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS00175 ^@ http://purl.uniprot.org/uniprot/I0HYI7 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/926550:CLDAP_RS11600 ^@ http://purl.uniprot.org/uniprot/I0I502 ^@ Caution|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS16245 ^@ http://purl.uniprot.org/uniprot/I0I7P9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS15485 ^@ http://purl.uniprot.org/uniprot/I0I793 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS12520 ^@ http://purl.uniprot.org/uniprot/I0I5J1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/926550:CLDAP_RS03465 ^@ http://purl.uniprot.org/uniprot/I0I0D8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/926550:CLDAP_RS16150 ^@ http://purl.uniprot.org/uniprot/I0I7M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS20625 ^@ http://purl.uniprot.org/uniprot/I0HYZ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS03005 ^@ http://purl.uniprot.org/uniprot/I0I048 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/926550:CLDAP_RS12100 ^@ http://purl.uniprot.org/uniprot/I0I5A4 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/926550:CLDAP_RS10440 ^@ http://purl.uniprot.org/uniprot/I0I4B6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/926550:CLDAP_RS20810 ^@ http://purl.uniprot.org/uniprot/I0I0R3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS02080 ^@ http://purl.uniprot.org/uniprot/I0HZL5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS03985 ^@ http://purl.uniprot.org/uniprot/I0I0P3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS11110 ^@ http://purl.uniprot.org/uniprot/I0I4Q4 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/926550:CLDAP_RS09785 ^@ http://purl.uniprot.org/uniprot/I0I3Y4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS08590 ^@ http://purl.uniprot.org/uniprot/I0I389 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS02485 ^@ http://purl.uniprot.org/uniprot/I0HZU5 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/926550:CLDAP_RS01600 ^@ http://purl.uniprot.org/uniprot/I0HZB8 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/926550:CLDAP_RS19690 ^@ http://purl.uniprot.org/uniprot/I0I9Q4 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/926550:CLDAP_RS06400 ^@ http://purl.uniprot.org/uniprot/I0I218 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS00015 ^@ http://purl.uniprot.org/uniprot/I0HYF5 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/926550:CLDAP_RS04565 ^@ http://purl.uniprot.org/uniprot/I0I107 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS11245 ^@ http://purl.uniprot.org/uniprot/I0I4T1 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS04105 ^@ http://purl.uniprot.org/uniprot/I0I0R7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS14840 ^@ http://purl.uniprot.org/uniprot/I0I6W3 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/926550:CLDAP_RS03365 ^@ http://purl.uniprot.org/uniprot/I0I0B7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS12935 ^@ http://purl.uniprot.org/uniprot/I0I5S1 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926550:CLDAP_RS05965 ^@ http://purl.uniprot.org/uniprot/I0I1T1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS10605 ^@ http://purl.uniprot.org/uniprot/I0I4E8 ^@ Cofactor|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily.|||Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/926550:CLDAP_RS05090 ^@ http://purl.uniprot.org/uniprot/I0I1B2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS14140 ^@ http://purl.uniprot.org/uniprot/I0I6G7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS16235 ^@ http://purl.uniprot.org/uniprot/I0I7P7 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/926550:CLDAP_RS15685 ^@ http://purl.uniprot.org/uniprot/I0I7D2 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/926550:CLDAP_RS01170 ^@ http://purl.uniprot.org/uniprot/I0HZ35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS04090 ^@ http://purl.uniprot.org/uniprot/I0I0R4 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/926550:CLDAP_RS05220 ^@ http://purl.uniprot.org/uniprot/I0I1D5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/926550:CLDAP_RS09275 ^@ http://purl.uniprot.org/uniprot/I0I3M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS01865 ^@ http://purl.uniprot.org/uniprot/I0HZH1 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/926550:CLDAP_RS08005 ^@ http://purl.uniprot.org/uniprot/I0I2X0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell inner membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/926550:CLDAP_RS07445 ^@ http://purl.uniprot.org/uniprot/I0I2L5 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS13065 ^@ http://purl.uniprot.org/uniprot/I0I5U7 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/926550:CLDAP_RS18615 ^@ http://purl.uniprot.org/uniprot/I0I933 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/926550:CLDAP_RS11085 ^@ http://purl.uniprot.org/uniprot/I0I4P9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS00685 ^@ http://purl.uniprot.org/uniprot/I0HYT8 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/926550:CLDAP_RS06725 ^@ http://purl.uniprot.org/uniprot/I0I280 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 39 family. http://togogenome.org/gene/926550:CLDAP_RS11775 ^@ http://purl.uniprot.org/uniprot/I0I537 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/926550:CLDAP_RS07120 ^@ http://purl.uniprot.org/uniprot/I0I2F1 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/926550:CLDAP_RS04415 ^@ http://purl.uniprot.org/uniprot/I0I0X7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926550:CLDAP_RS03420 ^@ http://purl.uniprot.org/uniprot/I0I0C9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS05145 ^@ http://purl.uniprot.org/uniprot/I0I1C3 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/926550:CLDAP_RS03485 ^@ http://purl.uniprot.org/uniprot/I0I0E2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS12020 ^@ http://purl.uniprot.org/uniprot/I0I585 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/926550:CLDAP_RS19535 ^@ http://purl.uniprot.org/uniprot/I0I9M2 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/926550:CLDAP_RS16190 ^@ http://purl.uniprot.org/uniprot/I0I7N6 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/926550:CLDAP_RS14705 ^@ http://purl.uniprot.org/uniprot/I0I6T5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/926550:CLDAP_RS00340 ^@ http://purl.uniprot.org/uniprot/I0HYM0 ^@ Similarity ^@ Belongs to the peptidase S9A family. http://togogenome.org/gene/926550:CLDAP_RS05175 ^@ http://purl.uniprot.org/uniprot/I0I1C6 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/926550:CLDAP_RS01475 ^@ http://purl.uniprot.org/uniprot/I0HZ93 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS01950 ^@ http://purl.uniprot.org/uniprot/I0HZI8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/926550:CLDAP_RS19660 ^@ http://purl.uniprot.org/uniprot/I0I9P8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/926550:CLDAP_RS07470 ^@ http://purl.uniprot.org/uniprot/I0I2M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS07640 ^@ http://purl.uniprot.org/uniprot/I0I2P9 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/926550:CLDAP_RS20475 ^@ http://purl.uniprot.org/uniprot/I0IA60 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.|||Catalyzes the NADPH-dependent reduction of [LysW]-aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926550:CLDAP_RS14590 ^@ http://purl.uniprot.org/uniprot/I0I6R1 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/926550:CLDAP_RS12810 ^@ http://purl.uniprot.org/uniprot/I0I5P7 ^@ Similarity ^@ Belongs to the FtsK/SpoIIIE/SftA family. http://togogenome.org/gene/926550:CLDAP_RS00535 ^@ http://purl.uniprot.org/uniprot/I0HYQ8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/926550:CLDAP_RS21065 ^@ http://purl.uniprot.org/uniprot/I0I2X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TatB family.|||Cell inner membrane http://togogenome.org/gene/926550:CLDAP_RS06050 ^@ http://purl.uniprot.org/uniprot/I0I1U8 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/926550:CLDAP_RS17475 ^@ http://purl.uniprot.org/uniprot/I0I8F1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/926550:CLDAP_RS12290 ^@ http://purl.uniprot.org/uniprot/I0I5E4 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/926550:CLDAP_RS05465 ^@ http://purl.uniprot.org/uniprot/I0I1I3 ^@ Cofactor|||PTM|||Subcellular Location Annotation ^@ Binds 2 heme groups per subunit.|||Binds 2 heme groups.|||Periplasm http://togogenome.org/gene/926550:CLDAP_RS12445 ^@ http://purl.uniprot.org/uniprot/I0I5H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS13640 ^@ http://purl.uniprot.org/uniprot/I0I663 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/926550:CLDAP_RS18060 ^@ http://purl.uniprot.org/uniprot/I0I8R8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS13455 ^@ http://purl.uniprot.org/uniprot/I0I625 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS18805 ^@ http://purl.uniprot.org/uniprot/I0I970 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/926550:CLDAP_RS06380 ^@ http://purl.uniprot.org/uniprot/I0I214 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/926550:CLDAP_RS09525 ^@ http://purl.uniprot.org/uniprot/I0I3S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS19480 ^@ http://purl.uniprot.org/uniprot/I0I9L0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/926550:CLDAP_RS21780 ^@ http://purl.uniprot.org/uniprot/I0I9V7 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/926550:CLDAP_RS00055 ^@ http://purl.uniprot.org/uniprot/I0HYG3 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/926550:CLDAP_RS07320 ^@ http://purl.uniprot.org/uniprot/I0I2J1 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS04390 ^@ http://purl.uniprot.org/uniprot/I0I0X2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926550:CLDAP_RS16465 ^@ http://purl.uniprot.org/uniprot/I0I7U2 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/926550:CLDAP_RS08710 ^@ http://purl.uniprot.org/uniprot/I0I3B4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/926550:CLDAP_RS20705 ^@ http://purl.uniprot.org/uniprot/I0HZS5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/926550:CLDAP_RS06195 ^@ http://purl.uniprot.org/uniprot/I0I1X6 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/926550:CLDAP_RS05205 ^@ http://purl.uniprot.org/uniprot/I0I1D2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS05750 ^@ http://purl.uniprot.org/uniprot/I0I1N9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/926550:CLDAP_RS01095 ^@ http://purl.uniprot.org/uniprot/I0HZ20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS00580 ^@ http://purl.uniprot.org/uniprot/I0HYR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS19750 ^@ http://purl.uniprot.org/uniprot/I0I9R4 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/926550:CLDAP_RS10390 ^@ http://purl.uniprot.org/uniprot/I0I4A6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS17875 ^@ http://purl.uniprot.org/uniprot/I0I8N1 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/926550:CLDAP_RS17190 ^@ http://purl.uniprot.org/uniprot/I0I894 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS15585 ^@ http://purl.uniprot.org/uniprot/I0I7B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS21345 ^@ http://purl.uniprot.org/uniprot/I0I5P0 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/926550:CLDAP_RS21930 ^@ http://purl.uniprot.org/uniprot/I0I4N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsbB family. BdbC subfamily.|||Membrane http://togogenome.org/gene/926550:CLDAP_RS09605 ^@ http://purl.uniprot.org/uniprot/I0I3U5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS13190 ^@ http://purl.uniprot.org/uniprot/I0I5X2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS20275 ^@ http://purl.uniprot.org/uniprot/I0IA20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS06610 ^@ http://purl.uniprot.org/uniprot/I0I261 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS02755 ^@ http://purl.uniprot.org/uniprot/I0HZZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS12790 ^@ http://purl.uniprot.org/uniprot/I0I5P3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/926550:CLDAP_RS12425 ^@ http://purl.uniprot.org/uniprot/I0I5H2 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/926550:CLDAP_RS07875 ^@ http://purl.uniprot.org/uniprot/I0I2U4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/926550:CLDAP_RS00060 ^@ http://purl.uniprot.org/uniprot/I0HYG4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926550:CLDAP_RS18750 ^@ http://purl.uniprot.org/uniprot/I0I960 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926550:CLDAP_RS20260 ^@ http://purl.uniprot.org/uniprot/I0IA17 ^@ Similarity ^@ Belongs to the archaeal-type GPI family. http://togogenome.org/gene/926550:CLDAP_RS04945 ^@ http://purl.uniprot.org/uniprot/I0I183 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926550:CLDAP_RS11145 ^@ http://purl.uniprot.org/uniprot/I0I4R1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/926550:CLDAP_RS08615 ^@ http://purl.uniprot.org/uniprot/I0I395 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/926550:CLDAP_RS18375 ^@ http://purl.uniprot.org/uniprot/I0I8Y2 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/926550:CLDAP_RS04245 ^@ http://purl.uniprot.org/uniprot/I0I0U4 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/926550:CLDAP_RS17600 ^@ http://purl.uniprot.org/uniprot/I0I8H8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS05560 ^@ http://purl.uniprot.org/uniprot/I0I1K0 ^@ Similarity ^@ Belongs to the beta-eliminating lyase family. http://togogenome.org/gene/926550:CLDAP_RS18555 ^@ http://purl.uniprot.org/uniprot/I0I921 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926550:CLDAP_RS19615 ^@ http://purl.uniprot.org/uniprot/I0I9N9 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/926550:CLDAP_RS02170 ^@ http://purl.uniprot.org/uniprot/I0HZN3 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/926550:CLDAP_RS11230 ^@ http://purl.uniprot.org/uniprot/I0I4S8 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/926550:CLDAP_RS21710 ^@ http://purl.uniprot.org/uniprot/I0I8Y9 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/926550:CLDAP_RS06135 ^@ http://purl.uniprot.org/uniprot/I0I1W4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/926550:CLDAP_RS14335 ^@ http://purl.uniprot.org/uniprot/I0I6K9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926550:CLDAP_RS20885 ^@ http://purl.uniprot.org/uniprot/I0I1G4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Binds a copper A center.|||Cell membrane|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/926550:CLDAP_RS18535 ^@ http://purl.uniprot.org/uniprot/I0I916 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/926550:CLDAP_RS13875 ^@ http://purl.uniprot.org/uniprot/I0I6B1 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/926550:CLDAP_RS21085 ^@ http://purl.uniprot.org/uniprot/I0I321 ^@ Caution|||Function|||Similarity ^@ 3'-5' exonuclease.|||Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.