http://togogenome.org/gene/926569:ANT_RS05035 ^@ http://purl.uniprot.org/uniprot/E8N3M8 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/926569:ANT_RS10110 ^@ http://purl.uniprot.org/uniprot/E8MXG5 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/926569:ANT_RS10195 ^@ http://purl.uniprot.org/uniprot/E8MXI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS04170 ^@ http://purl.uniprot.org/uniprot/E8N354 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/926569:ANT_RS05220 ^@ http://purl.uniprot.org/uniprot/E8N3R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/926569:ANT_RS05160 ^@ http://purl.uniprot.org/uniprot/E8N3Q4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/926569:ANT_RS01290 ^@ http://purl.uniprot.org/uniprot/E8MZV9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS00025 ^@ http://purl.uniprot.org/uniprot/E8MY94 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/926569:ANT_RS13750 ^@ http://purl.uniprot.org/uniprot/E8N142 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/926569:ANT_RS15685 ^@ http://purl.uniprot.org/uniprot/E8N321 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/926569:ANT_RS01930 ^@ http://purl.uniprot.org/uniprot/E8N0M6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS06495 ^@ http://purl.uniprot.org/uniprot/E8N4G7 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/926569:ANT_RS10220 ^@ http://purl.uniprot.org/uniprot/E8MXI8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/926569:ANT_RS14120 ^@ http://purl.uniprot.org/uniprot/E8N1B5 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/926569:ANT_RS14840 ^@ http://purl.uniprot.org/uniprot/E8N255 ^@ Similarity ^@ Belongs to the antibiotic N-acetyltransferase family. http://togogenome.org/gene/926569:ANT_RS00965 ^@ http://purl.uniprot.org/uniprot/E8MZ81 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS03845 ^@ http://purl.uniprot.org/uniprot/E8N2J7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926569:ANT_RS02740 ^@ http://purl.uniprot.org/uniprot/E8N1I1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/926569:ANT_RS09505 ^@ http://purl.uniprot.org/uniprot/E8N658 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/926569:ANT_RS10990 ^@ http://purl.uniprot.org/uniprot/E8MXZ8 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/926569:ANT_RS14595 ^@ http://purl.uniprot.org/uniprot/E8N207 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/926569:ANT_RS05685 ^@ http://purl.uniprot.org/uniprot/E8N405 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Monomer. http://togogenome.org/gene/926569:ANT_RS05115 ^@ http://purl.uniprot.org/uniprot/E8N3P4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/926569:ANT_RS01985 ^@ http://purl.uniprot.org/uniprot/E8N0N7 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/926569:ANT_RS09480 ^@ http://purl.uniprot.org/uniprot/E8N653 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/926569:ANT_RS13760 ^@ http://purl.uniprot.org/uniprot/E8N144 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS05290 ^@ http://purl.uniprot.org/uniprot/E8N3T0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926569:ANT_RS01390 ^@ http://purl.uniprot.org/uniprot/E8MZX9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/926569:ANT_RS10185 ^@ http://purl.uniprot.org/uniprot/E8MXI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS12415 ^@ http://purl.uniprot.org/uniprot/E8MZG9 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/926569:ANT_RS00825 ^@ http://purl.uniprot.org/uniprot/E8MZ56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/926569:ANT_RS05060 ^@ http://purl.uniprot.org/uniprot/E8N3N3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926569:ANT_RS06915 ^@ http://purl.uniprot.org/uniprot/E8N4P5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS11585 ^@ http://purl.uniprot.org/uniprot/E8MYL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/926569:ANT_RS08065 ^@ http://purl.uniprot.org/uniprot/E8N5C3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/926569:ANT_RS14185 ^@ http://purl.uniprot.org/uniprot/E8N1C8 ^@ Function ^@ CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/926569:ANT_RS01425 ^@ http://purl.uniprot.org/uniprot/E8MZY6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS12940 ^@ http://purl.uniprot.org/uniprot/E8MZS4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS09960 ^@ http://purl.uniprot.org/uniprot/E8N6F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/926569:ANT_RS12670 ^@ http://purl.uniprot.org/uniprot/E8MZM0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/926569:ANT_RS09585 ^@ http://purl.uniprot.org/uniprot/E8N670 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/926569:ANT_RS14160 ^@ http://purl.uniprot.org/uniprot/E8N1C3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/926569:ANT_RS09660 ^@ http://purl.uniprot.org/uniprot/E8N690 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/926569:ANT_RS05345 ^@ http://purl.uniprot.org/uniprot/E8N3T9 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/926569:ANT_RS08025 ^@ http://purl.uniprot.org/uniprot/E8N5B5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/926569:ANT_RS03325 ^@ http://purl.uniprot.org/uniprot/E8N1U5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS06565 ^@ http://purl.uniprot.org/uniprot/E8N4H9 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/926569:ANT_RS05195 ^@ http://purl.uniprot.org/uniprot/E8N3R1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926569:ANT_RS06895 ^@ http://purl.uniprot.org/uniprot/E8N4P1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/926569:ANT_RS01740 ^@ http://purl.uniprot.org/uniprot/E8N050 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/926569:ANT_RS14790 ^@ http://purl.uniprot.org/uniprot/E8N246 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS04080 ^@ http://purl.uniprot.org/uniprot/E8N2P4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS09595 ^@ http://purl.uniprot.org/uniprot/E8N672 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS15485 ^@ http://purl.uniprot.org/uniprot/E8N2Y1 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/926569:ANT_RS09015 ^@ http://purl.uniprot.org/uniprot/E8N5W0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/926569:ANT_RS12915 ^@ http://purl.uniprot.org/uniprot/E8MZR9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/926569:ANT_RS03490 ^@ http://purl.uniprot.org/uniprot/E8N2C8 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/926569:ANT_RS07430 ^@ http://purl.uniprot.org/uniprot/E8N4Z8 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/926569:ANT_RS13350 ^@ http://purl.uniprot.org/uniprot/E8N0F6 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/926569:ANT_RS10435 ^@ http://purl.uniprot.org/uniprot/E8MXN1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/926569:ANT_RS09715 ^@ http://purl.uniprot.org/uniprot/E8N6A2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/926569:ANT_RS09420 ^@ http://purl.uniprot.org/uniprot/E8N640 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05810 ^@ http://purl.uniprot.org/uniprot/E8N430 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/926569:ANT_RS17720 ^@ http://purl.uniprot.org/uniprot/E8MYQ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926569:ANT_RS00420 ^@ http://purl.uniprot.org/uniprot/E8MYH4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/926569:ANT_RS07350 ^@ http://purl.uniprot.org/uniprot/E8N4Y2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/926569:ANT_RS13580 ^@ http://purl.uniprot.org/uniprot/E8N0K4 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/926569:ANT_RS16650 ^@ http://purl.uniprot.org/uniprot/E8N180 ^@ Similarity ^@ Belongs to the peptidase M4 family. http://togogenome.org/gene/926569:ANT_RS10285 ^@ http://purl.uniprot.org/uniprot/E8MXK1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS07635 ^@ http://purl.uniprot.org/uniprot/E8N538 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/926569:ANT_RS06635 ^@ http://purl.uniprot.org/uniprot/E8N4J3 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/926569:ANT_RS01670 ^@ http://purl.uniprot.org/uniprot/E8N036 ^@ Similarity ^@ Belongs to the UPF0166 family. http://togogenome.org/gene/926569:ANT_RS05110 ^@ http://purl.uniprot.org/uniprot/E8N3P3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/926569:ANT_RS11600 ^@ http://purl.uniprot.org/uniprot/E8MYL3 ^@ Similarity ^@ Belongs to the LarC family. http://togogenome.org/gene/926569:ANT_RS05225 ^@ http://purl.uniprot.org/uniprot/E8N3R7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/926569:ANT_RS09035 ^@ http://purl.uniprot.org/uniprot/E8N5W4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/926569:ANT_RS04970 ^@ http://purl.uniprot.org/uniprot/E8N3L5 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/926569:ANT_RS05010 ^@ http://purl.uniprot.org/uniprot/E8N3M3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926569:ANT_RS12205 ^@ http://purl.uniprot.org/uniprot/E8MZC9 ^@ Similarity ^@ Belongs to the CRISPR-associated Csm3 family. http://togogenome.org/gene/926569:ANT_RS02055 ^@ http://purl.uniprot.org/uniprot/E8N0Q1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/926569:ANT_RS04865 ^@ http://purl.uniprot.org/uniprot/E8N3J4 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/926569:ANT_RS04990 ^@ http://purl.uniprot.org/uniprot/E8N3L9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/926569:ANT_RS04115 ^@ http://purl.uniprot.org/uniprot/E8N2Q1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/926569:ANT_RS08965 ^@ http://purl.uniprot.org/uniprot/E8N5V0 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/926569:ANT_RS10295 ^@ http://purl.uniprot.org/uniprot/E8MXK3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/926569:ANT_RS03675 ^@ http://purl.uniprot.org/uniprot/E8N2G3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05840 ^@ http://purl.uniprot.org/uniprot/E8N436 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/926569:ANT_RS14165 ^@ http://purl.uniprot.org/uniprot/E8N1C4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/926569:ANT_RS05720 ^@ http://purl.uniprot.org/uniprot/E8N412 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/926569:ANT_RS16805 ^@ http://purl.uniprot.org/uniprot/E8N544 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/926569:ANT_RS14700 ^@ http://purl.uniprot.org/uniprot/E8N229 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/926569:ANT_RS04675 ^@ http://purl.uniprot.org/uniprot/E8N3F6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS04530 ^@ http://purl.uniprot.org/uniprot/E8N3C5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS02585 ^@ http://purl.uniprot.org/uniprot/E8N110 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/926569:ANT_RS04325 ^@ http://purl.uniprot.org/uniprot/E8N385 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS01195 ^@ http://purl.uniprot.org/uniprot/E8MZT9 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/926569:ANT_RS08545 ^@ http://purl.uniprot.org/uniprot/E8N5L7 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/926569:ANT_RS09175 ^@ http://purl.uniprot.org/uniprot/E8N5Z2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/926569:ANT_RS12060 ^@ http://purl.uniprot.org/uniprot/E8MYW2 ^@ Function|||Similarity ^@ Belongs to the PemK/MazF family.|||Toxic component of a type II toxin-antitoxin (TA) system. http://togogenome.org/gene/926569:ANT_RS01230 ^@ http://purl.uniprot.org/uniprot/E8MZU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/926569:ANT_RS06300 ^@ http://purl.uniprot.org/uniprot/E8N4C7 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/926569:ANT_RS03320 ^@ http://purl.uniprot.org/uniprot/E8N1U4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS09865 ^@ http://purl.uniprot.org/uniprot/E8N6D3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS11270 ^@ http://purl.uniprot.org/uniprot/E8MY52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS01630 ^@ http://purl.uniprot.org/uniprot/E8N028 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/926569:ANT_RS15770 ^@ http://purl.uniprot.org/uniprot/E8N337 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/926569:ANT_RS05065 ^@ http://purl.uniprot.org/uniprot/E8N3N4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/926569:ANT_RS09240 ^@ http://purl.uniprot.org/uniprot/E8N605 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/926569:ANT_RS02175 ^@ http://purl.uniprot.org/uniprot/E8N0S6 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/926569:ANT_RS09250 ^@ http://purl.uniprot.org/uniprot/E8N607 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/926569:ANT_RS13450 ^@ http://purl.uniprot.org/uniprot/E8N0H7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/926569:ANT_RS14485 ^@ http://purl.uniprot.org/uniprot/E8N1Y5 ^@ Similarity ^@ Belongs to the cytochrome c-552 family. http://togogenome.org/gene/926569:ANT_RS08995 ^@ http://purl.uniprot.org/uniprot/E8N5V6 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/926569:ANT_RS05330 ^@ http://purl.uniprot.org/uniprot/E8N3T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS07015 ^@ http://purl.uniprot.org/uniprot/E8N4R5 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/926569:ANT_RS14055 ^@ http://purl.uniprot.org/uniprot/E8N1A2 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/926569:ANT_RS13140 ^@ http://purl.uniprot.org/uniprot/E8N0B4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS15735 ^@ http://purl.uniprot.org/uniprot/E8N330 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/926569:ANT_RS15465 ^@ http://purl.uniprot.org/uniprot/E8N2X7 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS04150 ^@ http://purl.uniprot.org/uniprot/E8N2Q8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926569:ANT_RS06545 ^@ http://purl.uniprot.org/uniprot/E8N4H7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS04215 ^@ http://purl.uniprot.org/uniprot/E8N363 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM19 family.|||Membrane http://togogenome.org/gene/926569:ANT_RS09710 ^@ http://purl.uniprot.org/uniprot/E8N6A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Membrane http://togogenome.org/gene/926569:ANT_RS04515 ^@ http://purl.uniprot.org/uniprot/E8N3C2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS09065 ^@ http://purl.uniprot.org/uniprot/E8N5X0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/926569:ANT_RS16535 ^@ http://purl.uniprot.org/uniprot/E8MY79 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/926569:ANT_RS11015 ^@ http://purl.uniprot.org/uniprot/E8MY03 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS03395 ^@ http://purl.uniprot.org/uniprot/E8N1V9 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/926569:ANT_RS10290 ^@ http://purl.uniprot.org/uniprot/E8MXK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/926569:ANT_RS04255 ^@ http://purl.uniprot.org/uniprot/E8N371 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/926569:ANT_RS06015 ^@ http://purl.uniprot.org/uniprot/E8N469 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS13985 ^@ http://purl.uniprot.org/uniprot/E8N188 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS00555 ^@ http://purl.uniprot.org/uniprot/E8MZ03 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS00335 ^@ http://purl.uniprot.org/uniprot/E8MYF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family.|||Membrane http://togogenome.org/gene/926569:ANT_RS00990 ^@ http://purl.uniprot.org/uniprot/E8MZ86 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/926569:ANT_RS06200 ^@ http://purl.uniprot.org/uniprot/E8N4A7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family. LysK subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS01735 ^@ http://purl.uniprot.org/uniprot/E8N049 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/926569:ANT_RS11640 ^@ http://purl.uniprot.org/uniprot/E8MYM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/926569:ANT_RS07020 ^@ http://purl.uniprot.org/uniprot/E8N4R6 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/926569:ANT_RS05690 ^@ http://purl.uniprot.org/uniprot/E8N406 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/926569:ANT_RS00845 ^@ http://purl.uniprot.org/uniprot/E8MZ60 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/926569:ANT_RS11570 ^@ http://purl.uniprot.org/uniprot/E8MYK7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS03965 ^@ http://purl.uniprot.org/uniprot/E8N2M1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS13625 ^@ http://purl.uniprot.org/uniprot/E8N0L2 ^@ Caution|||Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS13125 ^@ http://purl.uniprot.org/uniprot/E8N0B1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS15760 ^@ http://purl.uniprot.org/uniprot/E8N335 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS06720 ^@ http://purl.uniprot.org/uniprot/E8N4L1 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/926569:ANT_RS03130 ^@ http://purl.uniprot.org/uniprot/E8N1Q6 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/926569:ANT_RS03150 ^@ http://purl.uniprot.org/uniprot/E8N1R0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/926569:ANT_RS15130 ^@ http://purl.uniprot.org/uniprot/E8N2R0 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/926569:ANT_RS05760 ^@ http://purl.uniprot.org/uniprot/E8N420 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS12730 ^@ http://purl.uniprot.org/uniprot/E8MZN2 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/926569:ANT_RS10905 ^@ http://purl.uniprot.org/uniprot/E8MXY3 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS13305 ^@ http://purl.uniprot.org/uniprot/E8N0E6 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/926569:ANT_RS04175 ^@ http://purl.uniprot.org/uniprot/E8N355 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926569:ANT_RS13300 ^@ http://purl.uniprot.org/uniprot/E8N0E5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/926569:ANT_RS14680 ^@ http://purl.uniprot.org/uniprot/E8N225 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/926569:ANT_RS03825 ^@ http://purl.uniprot.org/uniprot/E8N2J3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS11685 ^@ http://purl.uniprot.org/uniprot/E8MYN0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS09055 ^@ http://purl.uniprot.org/uniprot/E8N5W8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/926569:ANT_RS03120 ^@ http://purl.uniprot.org/uniprot/E8N1Q4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/926569:ANT_RS09575 ^@ http://purl.uniprot.org/uniprot/E8N668 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS02765 ^@ http://purl.uniprot.org/uniprot/E8N1I6 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/926569:ANT_RS08060 ^@ http://purl.uniprot.org/uniprot/E8N5C2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/926569:ANT_RS04165 ^@ http://purl.uniprot.org/uniprot/E8N353 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/926569:ANT_RS17945 ^@ http://purl.uniprot.org/uniprot/E8N2X3 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/926569:ANT_RS04155 ^@ http://purl.uniprot.org/uniprot/E8N2Q9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926569:ANT_RS07415 ^@ http://purl.uniprot.org/uniprot/E8N4Z5 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/926569:ANT_RS08625 ^@ http://purl.uniprot.org/uniprot/E8N5N4 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/926569:ANT_RS11295 ^@ http://purl.uniprot.org/uniprot/E8MY57 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/926569:ANT_RS10540 ^@ http://purl.uniprot.org/uniprot/E8MXQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/926569:ANT_RS06995 ^@ http://purl.uniprot.org/uniprot/E8N4R1 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/926569:ANT_RS00215 ^@ http://purl.uniprot.org/uniprot/E8MYD2 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/926569:ANT_RS10525 ^@ http://purl.uniprot.org/uniprot/E8MXQ0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS13960 ^@ http://purl.uniprot.org/uniprot/E8N183 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS02770 ^@ http://purl.uniprot.org/uniprot/E8N1I7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/926569:ANT_RS15820 ^@ http://purl.uniprot.org/uniprot/E8N346 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS09380 ^@ http://purl.uniprot.org/uniprot/E8N633 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/926569:ANT_RS15225 ^@ http://purl.uniprot.org/uniprot/E8N2S8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/926569:ANT_RS06310 ^@ http://purl.uniprot.org/uniprot/E8N4C9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS02750 ^@ http://purl.uniprot.org/uniprot/E8N1I3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/926569:ANT_RS02945 ^@ http://purl.uniprot.org/uniprot/E8N1M1 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/926569:ANT_RS03855 ^@ http://purl.uniprot.org/uniprot/E8N2J9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS01965 ^@ http://purl.uniprot.org/uniprot/E8N0N3 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/926569:ANT_RS16045 ^@ http://purl.uniprot.org/uniprot/E8N2K2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS14735 ^@ http://purl.uniprot.org/uniprot/E8N236 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/926569:ANT_RS10085 ^@ http://purl.uniprot.org/uniprot/E8MXG1 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/926569:ANT_RS00915 ^@ http://purl.uniprot.org/uniprot/E8MZ70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS08420 ^@ http://purl.uniprot.org/uniprot/E8N5J1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/926569:ANT_RS14480 ^@ http://purl.uniprot.org/uniprot/E8N1Y4 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the NapC/NirT/NrfH family.|||Binds 4 heme groups per subunit. http://togogenome.org/gene/926569:ANT_RS03800 ^@ http://purl.uniprot.org/uniprot/E8N2I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS03385 ^@ http://purl.uniprot.org/uniprot/E8N1V7 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/926569:ANT_RS06480 ^@ http://purl.uniprot.org/uniprot/E8N4G4 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/926569:ANT_RS04130 ^@ http://purl.uniprot.org/uniprot/E8N2Q4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS06900 ^@ http://purl.uniprot.org/uniprot/E8N4P2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/926569:ANT_RS12525 ^@ http://purl.uniprot.org/uniprot/E8MZJ1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/926569:ANT_RS07630 ^@ http://purl.uniprot.org/uniprot/E8N537 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/926569:ANT_RS00755 ^@ http://purl.uniprot.org/uniprot/E8MZ42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS06875 ^@ http://purl.uniprot.org/uniprot/E8N4N7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS13145 ^@ http://purl.uniprot.org/uniprot/E8N0B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS06080 ^@ http://purl.uniprot.org/uniprot/E8N483 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/926569:ANT_RS04625 ^@ http://purl.uniprot.org/uniprot/E8N3E5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS03885 ^@ http://purl.uniprot.org/uniprot/E8N2K5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS12535 ^@ http://purl.uniprot.org/uniprot/E8MZJ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/926569:ANT_RS01115 ^@ http://purl.uniprot.org/uniprot/E8MZB5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/926569:ANT_RS04900 ^@ http://purl.uniprot.org/uniprot/E8N3K1 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/926569:ANT_RS02690 ^@ http://purl.uniprot.org/uniprot/E8N1H1 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/926569:ANT_RS05150 ^@ http://purl.uniprot.org/uniprot/E8N3Q2 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/926569:ANT_RS07650 ^@ http://purl.uniprot.org/uniprot/E8N541 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/926569:ANT_RS01210 ^@ http://purl.uniprot.org/uniprot/E8MZU3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS07100 ^@ http://purl.uniprot.org/uniprot/E8N4T2 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/926569:ANT_RS15900 ^@ http://purl.uniprot.org/uniprot/E8MZ83 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/926569:ANT_RS01380 ^@ http://purl.uniprot.org/uniprot/E8MZX7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/926569:ANT_RS11835 ^@ http://purl.uniprot.org/uniprot/E8MYR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS11850 ^@ http://purl.uniprot.org/uniprot/E8MYR4 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/926569:ANT_RS09445 ^@ http://purl.uniprot.org/uniprot/E8N646 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/926569:ANT_RS12510 ^@ http://purl.uniprot.org/uniprot/E8MZI8 ^@ Function ^@ Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. http://togogenome.org/gene/926569:ANT_RS15395 ^@ http://purl.uniprot.org/uniprot/E8N2W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS12450 ^@ http://purl.uniprot.org/uniprot/E8MZH6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/926569:ANT_RS03000 ^@ http://purl.uniprot.org/uniprot/E8N1N2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS07170 ^@ http://purl.uniprot.org/uniprot/E8N4U7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/926569:ANT_RS13120 ^@ http://purl.uniprot.org/uniprot/E8N0B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS12245 ^@ http://purl.uniprot.org/uniprot/E8MZD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/926569:ANT_RS04185 ^@ http://purl.uniprot.org/uniprot/E8N357 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926569:ANT_RS02405 ^@ http://purl.uniprot.org/uniprot/E8N0X3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/926569:ANT_RS04225 ^@ http://purl.uniprot.org/uniprot/E8N365 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/926569:ANT_RS14625 ^@ http://purl.uniprot.org/uniprot/E8N213 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/926569:ANT_RS11035 ^@ http://purl.uniprot.org/uniprot/E8MY08 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/926569:ANT_RS08140 ^@ http://purl.uniprot.org/uniprot/E8N5D8 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/926569:ANT_RS04450 ^@ http://purl.uniprot.org/uniprot/E8N3A9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS04880 ^@ http://purl.uniprot.org/uniprot/E8N3J7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/926569:ANT_RS13935 ^@ http://purl.uniprot.org/uniprot/E8N178 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/926569:ANT_RS09945 ^@ http://purl.uniprot.org/uniprot/E8N6F1 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family. http://togogenome.org/gene/926569:ANT_RS06345 ^@ http://purl.uniprot.org/uniprot/E8N4D6 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/926569:ANT_RS12685 ^@ http://purl.uniprot.org/uniprot/E8MZM3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/926569:ANT_RS05520 ^@ http://purl.uniprot.org/uniprot/E8N3X3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/926569:ANT_RS03510 ^@ http://purl.uniprot.org/uniprot/E8N2D2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/926569:ANT_RS05080 ^@ http://purl.uniprot.org/uniprot/E8N3N7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/926569:ANT_RS09290 ^@ http://purl.uniprot.org/uniprot/E8N615 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/926569:ANT_RS11420 ^@ http://purl.uniprot.org/uniprot/E8MY82 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/926569:ANT_RS08960 ^@ http://purl.uniprot.org/uniprot/E8N5U9 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/926569:ANT_RS00675 ^@ http://purl.uniprot.org/uniprot/E8MZ26 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/926569:ANT_RS03275 ^@ http://purl.uniprot.org/uniprot/E8N1T5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS07740 ^@ http://purl.uniprot.org/uniprot/E8N561 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/926569:ANT_RS05675 ^@ http://purl.uniprot.org/uniprot/E8N403 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/926569:ANT_RS08790 ^@ http://purl.uniprot.org/uniprot/E8N5R8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/926569:ANT_RS06110 ^@ http://purl.uniprot.org/uniprot/E8N489 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS09125 ^@ http://purl.uniprot.org/uniprot/E8N5Y2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/926569:ANT_RS05040 ^@ http://purl.uniprot.org/uniprot/E8N3M9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/926569:ANT_RS09940 ^@ http://purl.uniprot.org/uniprot/E8N6F0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/926569:ANT_RS00020 ^@ http://purl.uniprot.org/uniprot/E8MY92 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/926569:ANT_RS08325 ^@ http://purl.uniprot.org/uniprot/E8N5H2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/926569:ANT_RS00060 ^@ http://purl.uniprot.org/uniprot/E8MYA1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS04210 ^@ http://purl.uniprot.org/uniprot/E8N362 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926569:ANT_RS06840 ^@ http://purl.uniprot.org/uniprot/E8N4N1 ^@ Similarity ^@ Belongs to the ribulokinase family. http://togogenome.org/gene/926569:ANT_RS02715 ^@ http://purl.uniprot.org/uniprot/E8N1H6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS04505 ^@ http://purl.uniprot.org/uniprot/E8N3C0 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/926569:ANT_RS02270 ^@ http://purl.uniprot.org/uniprot/E8N0U5 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/926569:ANT_RS06030 ^@ http://purl.uniprot.org/uniprot/E8N472 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/926569:ANT_RS09005 ^@ http://purl.uniprot.org/uniprot/E8N5V8 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/926569:ANT_RS05140 ^@ http://purl.uniprot.org/uniprot/E8N3Q0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/926569:ANT_RS15300 ^@ http://purl.uniprot.org/uniprot/E8N2U4 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/926569:ANT_RS00380 ^@ http://purl.uniprot.org/uniprot/E8MYG6 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/926569:ANT_RS03710 ^@ http://purl.uniprot.org/uniprot/E8N2H0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS06460 ^@ http://purl.uniprot.org/uniprot/E8N4G0 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/926569:ANT_RS09355 ^@ http://purl.uniprot.org/uniprot/E8N628 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05865 ^@ http://purl.uniprot.org/uniprot/E8N441 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/926569:ANT_RS11635 ^@ http://purl.uniprot.org/uniprot/E8MYM0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/926569:ANT_RS12200 ^@ http://purl.uniprot.org/uniprot/E8MZC8 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm2 family.|||This subunit may be involved in monitoring complementarity of crRNA and target RNA. http://togogenome.org/gene/926569:ANT_RS04100 ^@ http://purl.uniprot.org/uniprot/E8N2P8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/926569:ANT_RS16775 ^@ http://purl.uniprot.org/uniprot/E8N1S5 ^@ Similarity|||Subunit ^@ Belongs to the CMP-NeuNAc synthase family.|||Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/926569:ANT_RS04860 ^@ http://purl.uniprot.org/uniprot/E8N3J3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/926569:ANT_RS04190 ^@ http://purl.uniprot.org/uniprot/E8N358 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926569:ANT_RS03165 ^@ http://purl.uniprot.org/uniprot/E8N1R3 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/926569:ANT_RS11290 ^@ http://purl.uniprot.org/uniprot/E8MY56 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/926569:ANT_RS02095 ^@ http://purl.uniprot.org/uniprot/E8N0Q9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/926569:ANT_RS10330 ^@ http://purl.uniprot.org/uniprot/E8MXL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS07225 ^@ http://purl.uniprot.org/uniprot/E8N4V8 ^@ Function|||Similarity ^@ Belongs to the CofC family.|||Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. http://togogenome.org/gene/926569:ANT_RS03745 ^@ http://purl.uniprot.org/uniprot/E8N2H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS13670 ^@ http://purl.uniprot.org/uniprot/E8N0M0 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/926569:ANT_RS09580 ^@ http://purl.uniprot.org/uniprot/E8N669 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/926569:ANT_RS02005 ^@ http://purl.uniprot.org/uniprot/E8N0P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS05280 ^@ http://purl.uniprot.org/uniprot/E8N3S8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/926569:ANT_RS04875 ^@ http://purl.uniprot.org/uniprot/E8N3J6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS01955 ^@ http://purl.uniprot.org/uniprot/E8N0N1 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/926569:ANT_RS00235 ^@ http://purl.uniprot.org/uniprot/E8MYD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/926569:ANT_RS14905 ^@ http://purl.uniprot.org/uniprot/E8N268 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926569:ANT_RS08570 ^@ http://purl.uniprot.org/uniprot/E8N5M3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS08745 ^@ http://purl.uniprot.org/uniprot/E8N5R0 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/926569:ANT_RS11010 ^@ http://purl.uniprot.org/uniprot/E8MY02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS14920 ^@ http://purl.uniprot.org/uniprot/E8N271 ^@ Similarity ^@ In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/926569:ANT_RS02330 ^@ http://purl.uniprot.org/uniprot/E8N0V8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS01730 ^@ http://purl.uniprot.org/uniprot/E8N048 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/926569:ANT_RS07380 ^@ http://purl.uniprot.org/uniprot/E8N4Y8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS08830 ^@ http://purl.uniprot.org/uniprot/E8N5S6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS04060 ^@ http://purl.uniprot.org/uniprot/E8N2P0 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/926569:ANT_RS03065 ^@ http://purl.uniprot.org/uniprot/E8N1P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS12475 ^@ http://purl.uniprot.org/uniprot/E8MZI1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/926569:ANT_RS10215 ^@ http://purl.uniprot.org/uniprot/E8MXI7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/926569:ANT_RS11335 ^@ http://purl.uniprot.org/uniprot/E8MY65 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS12790 ^@ http://purl.uniprot.org/uniprot/E8MZP4 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/926569:ANT_RS13825 ^@ http://purl.uniprot.org/uniprot/E8N157 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS12595 ^@ http://purl.uniprot.org/uniprot/E8MZK5 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/926569:ANT_RS13015 ^@ http://purl.uniprot.org/uniprot/E8N088 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS00245 ^@ http://purl.uniprot.org/uniprot/E8MYD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PucC family.|||Membrane http://togogenome.org/gene/926569:ANT_RS14780 ^@ http://purl.uniprot.org/uniprot/E8N244 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS15045 ^@ http://purl.uniprot.org/uniprot/E8N295 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.|||Homodimer. http://togogenome.org/gene/926569:ANT_RS01625 ^@ http://purl.uniprot.org/uniprot/E8N027 ^@ Similarity ^@ Belongs to the ketol-acid reductoisomerase family. http://togogenome.org/gene/926569:ANT_RS01225 ^@ http://purl.uniprot.org/uniprot/E8MZU6 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/926569:ANT_RS01575 ^@ http://purl.uniprot.org/uniprot/E8N017 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/926569:ANT_RS06740 ^@ http://purl.uniprot.org/uniprot/E8N4L5 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/926569:ANT_RS07395 ^@ http://purl.uniprot.org/uniprot/E8N4Z1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/926569:ANT_RS11700 ^@ http://purl.uniprot.org/uniprot/E8MYN3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS04030 ^@ http://purl.uniprot.org/uniprot/E8N2N5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS15625 ^@ http://purl.uniprot.org/uniprot/E8N308 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS14035 ^@ http://purl.uniprot.org/uniprot/E8N198 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS08750 ^@ http://purl.uniprot.org/uniprot/E8N5R1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/926569:ANT_RS11320 ^@ http://purl.uniprot.org/uniprot/E8MY62 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/926569:ANT_RS01570 ^@ http://purl.uniprot.org/uniprot/E8N016 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/926569:ANT_RS02415 ^@ http://purl.uniprot.org/uniprot/E8N0L2 ^@ Caution|||Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS13570 ^@ http://purl.uniprot.org/uniprot/E8N0K2 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/926569:ANT_RS05650 ^@ http://purl.uniprot.org/uniprot/E8N3Z8 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/926569:ANT_RS10545 ^@ http://purl.uniprot.org/uniprot/E8MXQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS17995 ^@ http://purl.uniprot.org/uniprot/E8N5Y5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||In the C-terminal section; belongs to the complex I 49 kDa subunit family.|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926569:ANT_RS12440 ^@ http://purl.uniprot.org/uniprot/E8MZH4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/926569:ANT_RS14250 ^@ http://purl.uniprot.org/uniprot/E8N1E1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS02700 ^@ http://purl.uniprot.org/uniprot/E8N1H3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS11380 ^@ http://purl.uniprot.org/uniprot/E8MY74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/926569:ANT_RS11000 ^@ http://purl.uniprot.org/uniprot/E8MY00 ^@ Similarity ^@ Belongs to the complex I 20 kDa subunit family. http://togogenome.org/gene/926569:ANT_RS15775 ^@ http://purl.uniprot.org/uniprot/E8N338 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/926569:ANT_RS12755 ^@ http://purl.uniprot.org/uniprot/E8MZN7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/926569:ANT_RS03685 ^@ http://purl.uniprot.org/uniprot/E8N2G5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS08155 ^@ http://purl.uniprot.org/uniprot/E8N5E1 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/926569:ANT_RS05050 ^@ http://purl.uniprot.org/uniprot/E8N3N1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/926569:ANT_RS13755 ^@ http://purl.uniprot.org/uniprot/E8N143 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/926569:ANT_RS10270 ^@ http://purl.uniprot.org/uniprot/E8MXJ8 ^@ Similarity ^@ Belongs to the Lgt family. http://togogenome.org/gene/926569:ANT_RS08955 ^@ http://purl.uniprot.org/uniprot/E8N5U8 ^@ Similarity ^@ Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/926569:ANT_RS13335 ^@ http://purl.uniprot.org/uniprot/E8N0F3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS12265 ^@ http://purl.uniprot.org/uniprot/E8MZE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS12405 ^@ http://purl.uniprot.org/uniprot/E8MZG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family.|||Membrane http://togogenome.org/gene/926569:ANT_RS03810 ^@ http://purl.uniprot.org/uniprot/E8N2I9 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/926569:ANT_RS05200 ^@ http://purl.uniprot.org/uniprot/E8N3R2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/926569:ANT_RS08935 ^@ http://purl.uniprot.org/uniprot/E8N5U4 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/926569:ANT_RS01485 ^@ http://purl.uniprot.org/uniprot/E8MZZ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS04825 ^@ http://purl.uniprot.org/uniprot/E8N3I6 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/926569:ANT_RS10350 ^@ http://purl.uniprot.org/uniprot/E8MXL5 ^@ Similarity ^@ Belongs to the spermidine/spermine synthase family. http://togogenome.org/gene/926569:ANT_RS13455 ^@ http://purl.uniprot.org/uniprot/E8N0H8 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/926569:ANT_RS14865 ^@ http://purl.uniprot.org/uniprot/E8N260 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/926569:ANT_RS01160 ^@ http://purl.uniprot.org/uniprot/E8MZC4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/926569:ANT_RS16095 ^@ http://purl.uniprot.org/uniprot/E8N3F4 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/926569:ANT_RS13415 ^@ http://purl.uniprot.org/uniprot/E8N0G9 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/926569:ANT_RS06600 ^@ http://purl.uniprot.org/uniprot/E8N4I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CitM (TC 2.A.11) transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS12295 ^@ http://purl.uniprot.org/uniprot/E8MZE7 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/926569:ANT_RS12380 ^@ http://purl.uniprot.org/uniprot/E8MZG3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS05130 ^@ http://purl.uniprot.org/uniprot/E8N3P8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/926569:ANT_RS03270 ^@ http://purl.uniprot.org/uniprot/E8N1T4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS02665 ^@ http://purl.uniprot.org/uniprot/E8N126 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/926569:ANT_RS06135 ^@ http://purl.uniprot.org/uniprot/E8N493 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/926569:ANT_RS08345 ^@ http://purl.uniprot.org/uniprot/E8N5H6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/926569:ANT_RS16065 ^@ http://purl.uniprot.org/uniprot/E8N391 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/926569:ANT_RS10970 ^@ http://purl.uniprot.org/uniprot/E8MXZ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS16615 ^@ http://purl.uniprot.org/uniprot/E8MZN1 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/926569:ANT_RS01685 ^@ http://purl.uniprot.org/uniprot/E8N039 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS14765 ^@ http://purl.uniprot.org/uniprot/E8N241 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/926569:ANT_RS10450 ^@ http://purl.uniprot.org/uniprot/E8MXN4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/926569:ANT_RS14040 ^@ http://purl.uniprot.org/uniprot/E8N199 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/926569:ANT_RS06340 ^@ http://purl.uniprot.org/uniprot/E8N4D5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926569:ANT_RS08950 ^@ http://purl.uniprot.org/uniprot/E8N5U7 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/926569:ANT_RS11470 ^@ http://purl.uniprot.org/uniprot/E8MYI7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05475 ^@ http://purl.uniprot.org/uniprot/E8N3W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS06475 ^@ http://purl.uniprot.org/uniprot/E8N4G3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS01175 ^@ http://purl.uniprot.org/uniprot/E8MZT5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/926569:ANT_RS12470 ^@ http://purl.uniprot.org/uniprot/E8MZI0 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/926569:ANT_RS08365 ^@ http://purl.uniprot.org/uniprot/E8N5I0 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/926569:ANT_RS14460 ^@ http://purl.uniprot.org/uniprot/E8N1Y0 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/926569:ANT_RS13315 ^@ http://purl.uniprot.org/uniprot/E8N0E8 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the FBP aldolase/phosphatase family.|||Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).|||Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.|||Homooctamer; dimer of tetramers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS05985 ^@ http://purl.uniprot.org/uniprot/E8N463 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS11195 ^@ http://purl.uniprot.org/uniprot/E8MY37 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS11625 ^@ http://purl.uniprot.org/uniprot/E8MYL8 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926569:ANT_RS05385 ^@ http://purl.uniprot.org/uniprot/E8N3U7 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/926569:ANT_RS02935 ^@ http://purl.uniprot.org/uniprot/E8N1L9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/926569:ANT_RS09935 ^@ http://purl.uniprot.org/uniprot/E8N6E9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/926569:ANT_RS02745 ^@ http://purl.uniprot.org/uniprot/E8N1I2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/926569:ANT_RS01675 ^@ http://purl.uniprot.org/uniprot/E8N037 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/926569:ANT_RS01440 ^@ http://purl.uniprot.org/uniprot/E8MZY9 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/926569:ANT_RS08110 ^@ http://purl.uniprot.org/uniprot/E8N5D2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/926569:ANT_RS04845 ^@ http://purl.uniprot.org/uniprot/E8N3J0 ^@ Similarity ^@ Belongs to the MreC family. http://togogenome.org/gene/926569:ANT_RS04950 ^@ http://purl.uniprot.org/uniprot/E8N3L1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS06235 ^@ http://purl.uniprot.org/uniprot/E8N4B4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/926569:ANT_RS00325 ^@ http://purl.uniprot.org/uniprot/E8MYF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS06620 ^@ http://purl.uniprot.org/uniprot/E8N4J0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/926569:ANT_RS05600 ^@ http://purl.uniprot.org/uniprot/E8N3Y9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS05025 ^@ http://purl.uniprot.org/uniprot/E8N3M6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/926569:ANT_RS14630 ^@ http://purl.uniprot.org/uniprot/E8N214 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/926569:ANT_RS04415 ^@ http://purl.uniprot.org/uniprot/E8N3A2 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/926569:ANT_RS00385 ^@ http://purl.uniprot.org/uniprot/E8MYG7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/926569:ANT_RS06020 ^@ http://purl.uniprot.org/uniprot/E8N470 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/926569:ANT_RS00810 ^@ http://purl.uniprot.org/uniprot/E8MZ53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/926569:ANT_RS02625 ^@ http://purl.uniprot.org/uniprot/E8N118 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS11830 ^@ http://purl.uniprot.org/uniprot/E8MYR0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/926569:ANT_RS05430 ^@ http://purl.uniprot.org/uniprot/E8N3V6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/926569:ANT_RS04205 ^@ http://purl.uniprot.org/uniprot/E8N361 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/926569:ANT_RS13065 ^@ http://purl.uniprot.org/uniprot/E8N099 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS03595 ^@ http://purl.uniprot.org/uniprot/E8N2E8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutC family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/926569:ANT_RS05780 ^@ http://purl.uniprot.org/uniprot/E8N424 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS15680 ^@ http://purl.uniprot.org/uniprot/E8N320 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/926569:ANT_RS05575 ^@ http://purl.uniprot.org/uniprot/E8N3Y4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/926569:ANT_RS08445 ^@ http://purl.uniprot.org/uniprot/E8N5J6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS10460 ^@ http://purl.uniprot.org/uniprot/E8MXN6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/926569:ANT_RS06215 ^@ http://purl.uniprot.org/uniprot/E8N4B0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.|||Catalyzes the NADPH-dependent reduction of [LysW]-aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS02925 ^@ http://purl.uniprot.org/uniprot/E8N1L7 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/926569:ANT_RS12775 ^@ http://purl.uniprot.org/uniprot/E8MZP1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS07565 ^@ http://purl.uniprot.org/uniprot/E8N524 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/926569:ANT_RS15545 ^@ http://purl.uniprot.org/uniprot/E8N2Z3 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/926569:ANT_RS00750 ^@ http://purl.uniprot.org/uniprot/E8MZ41 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS07485 ^@ http://purl.uniprot.org/uniprot/E8N509 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase C15 family.|||Cytoplasm|||Homotetramer.|||Removes 5-oxoproline from various penultimate amino acid residues except L-proline. http://togogenome.org/gene/926569:ANT_RS07940 ^@ http://purl.uniprot.org/uniprot/E8N598 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS04085 ^@ http://purl.uniprot.org/uniprot/E8N2P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS11385 ^@ http://purl.uniprot.org/uniprot/E8MY75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/926569:ANT_RS14125 ^@ http://purl.uniprot.org/uniprot/E8N1B6 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/926569:ANT_RS11450 ^@ http://purl.uniprot.org/uniprot/E8MY88 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/926569:ANT_RS07125 ^@ http://purl.uniprot.org/uniprot/E8N4T8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS04795 ^@ http://purl.uniprot.org/uniprot/E8N3I0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS06155 ^@ http://purl.uniprot.org/uniprot/E8N497 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/926569:ANT_RS01925 ^@ http://purl.uniprot.org/uniprot/E8N0M5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS01850 ^@ http://purl.uniprot.org/uniprot/E8N072 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS09450 ^@ http://purl.uniprot.org/uniprot/E8N647 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/926569:ANT_RS13835 ^@ http://purl.uniprot.org/uniprot/E8N159 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/926569:ANT_RS15270 ^@ http://purl.uniprot.org/uniprot/E8N2T8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS11455 ^@ http://purl.uniprot.org/uniprot/E8MY89 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/926569:ANT_RS18015 ^@ http://purl.uniprot.org/uniprot/E8MZK7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/926569:ANT_RS06405 ^@ http://purl.uniprot.org/uniprot/E8N4E6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS12445 ^@ http://purl.uniprot.org/uniprot/E8MZH5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/926569:ANT_RS11285 ^@ http://purl.uniprot.org/uniprot/E8MY55 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/926569:ANT_RS02280 ^@ http://purl.uniprot.org/uniprot/E8N0U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS04810 ^@ http://purl.uniprot.org/uniprot/E8N3I3 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/926569:ANT_RS11410 ^@ http://purl.uniprot.org/uniprot/E8MY80 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/926569:ANT_RS12210 ^@ http://purl.uniprot.org/uniprot/E8MZD0 ^@ Similarity ^@ Belongs to the CRISPR-associated Csm4 family. http://togogenome.org/gene/926569:ANT_RS06265 ^@ http://purl.uniprot.org/uniprot/E8N4C1 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/926569:ANT_RS03110 ^@ http://purl.uniprot.org/uniprot/E8N1Q1 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS04340 ^@ http://purl.uniprot.org/uniprot/E8N387 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/926569:ANT_RS05210 ^@ http://purl.uniprot.org/uniprot/E8N3R4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926569:ANT_RS00735 ^@ http://purl.uniprot.org/uniprot/E8MZ38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/926569:ANT_RS06905 ^@ http://purl.uniprot.org/uniprot/E8N4P3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/926569:ANT_RS04145 ^@ http://purl.uniprot.org/uniprot/E8N2Q7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926569:ANT_RS03705 ^@ http://purl.uniprot.org/uniprot/E8N2G9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05945 ^@ http://purl.uniprot.org/uniprot/E8N456 ^@ Cofactor|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily.|||Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/926569:ANT_RS10325 ^@ http://purl.uniprot.org/uniprot/E8MXL0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/926569:ANT_RS07345 ^@ http://purl.uniprot.org/uniprot/E8N4Y1 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/926569:ANT_RS15950 ^@ http://purl.uniprot.org/uniprot/E8N044 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05580 ^@ http://purl.uniprot.org/uniprot/E8N3Y5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MsrQ family.|||Binds 1 FMN per subunit.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Cell membrane|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Membrane|||Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain. http://togogenome.org/gene/926569:ANT_RS15005 ^@ http://purl.uniprot.org/uniprot/E8N287 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/926569:ANT_RS05665 ^@ http://purl.uniprot.org/uniprot/E8N401 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/926569:ANT_RS15295 ^@ http://purl.uniprot.org/uniprot/E8N2U3 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/926569:ANT_RS04690 ^@ http://purl.uniprot.org/uniprot/E8N3F9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926569:ANT_RS04435 ^@ http://purl.uniprot.org/uniprot/E8N3A6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS01480 ^@ http://purl.uniprot.org/uniprot/E8MZZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05800 ^@ http://purl.uniprot.org/uniprot/E8N428 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/926569:ANT_RS06195 ^@ http://purl.uniprot.org/uniprot/E8N4A6 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/926569:ANT_RS13990 ^@ http://purl.uniprot.org/uniprot/E8N189 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/926569:ANT_RS06950 ^@ http://purl.uniprot.org/uniprot/E8N4Q1 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/926569:ANT_RS01360 ^@ http://purl.uniprot.org/uniprot/E8MZX3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/926569:ANT_RS11025 ^@ http://purl.uniprot.org/uniprot/E8MY05 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS12155 ^@ http://purl.uniprot.org/uniprot/E8MYY2 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS00545 ^@ http://purl.uniprot.org/uniprot/E8MZ01 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/926569:ANT_RS12195 ^@ http://purl.uniprot.org/uniprot/E8MZC7 ^@ Similarity ^@ Belongs to the CRISPR-associated Cas10/Csm1 family. http://togogenome.org/gene/926569:ANT_RS13000 ^@ http://purl.uniprot.org/uniprot/E8N085 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS13805 ^@ http://purl.uniprot.org/uniprot/E8N153 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/926569:ANT_RS00085 ^@ http://purl.uniprot.org/uniprot/E8MYA7 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/926569:ANT_RS01935 ^@ http://purl.uniprot.org/uniprot/E8N0M7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS02930 ^@ http://purl.uniprot.org/uniprot/E8N1L8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/926569:ANT_RS08035 ^@ http://purl.uniprot.org/uniprot/E8N5B7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/926569:ANT_RS10955 ^@ http://purl.uniprot.org/uniprot/E8MXZ1 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/926569:ANT_RS07375 ^@ http://purl.uniprot.org/uniprot/E8N4Y7 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926569:ANT_RS02185 ^@ http://purl.uniprot.org/uniprot/E8N0S8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS01610 ^@ http://purl.uniprot.org/uniprot/E8N024 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS15615 ^@ http://purl.uniprot.org/uniprot/E8N306 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/926569:ANT_RS04310 ^@ http://purl.uniprot.org/uniprot/E8N382 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/926569:ANT_RS13060 ^@ http://purl.uniprot.org/uniprot/E8N098 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/926569:ANT_RS11210 ^@ http://purl.uniprot.org/uniprot/E8MY40 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/926569:ANT_RS11885 ^@ http://purl.uniprot.org/uniprot/E8MYS1 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/926569:ANT_RS02320 ^@ http://purl.uniprot.org/uniprot/E8N0V6 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/926569:ANT_RS08415 ^@ http://purl.uniprot.org/uniprot/E8N5J0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/926569:ANT_RS04335 ^@ http://purl.uniprot.org/uniprot/E8N386 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/926569:ANT_RS05775 ^@ http://purl.uniprot.org/uniprot/E8N423 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/926569:ANT_RS05975 ^@ http://purl.uniprot.org/uniprot/E8N461 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/926569:ANT_RS06630 ^@ http://purl.uniprot.org/uniprot/E8N4J2 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/926569:ANT_RS14860 ^@ http://purl.uniprot.org/uniprot/E8N259 ^@ Function ^@ Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. http://togogenome.org/gene/926569:ANT_RS06880 ^@ http://purl.uniprot.org/uniprot/E8N4N8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/926569:ANT_RS16055 ^@ http://purl.uniprot.org/uniprot/E8N2N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS01565 ^@ http://purl.uniprot.org/uniprot/E8N015 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/926569:ANT_RS12760 ^@ http://purl.uniprot.org/uniprot/E8MZN8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/926569:ANT_RS07730 ^@ http://purl.uniprot.org/uniprot/E8N559 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/926569:ANT_RS08285 ^@ http://purl.uniprot.org/uniprot/E8N5G5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS07135 ^@ http://purl.uniprot.org/uniprot/E8N4U0 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/926569:ANT_RS09750 ^@ http://purl.uniprot.org/uniprot/E8N6B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS08405 ^@ http://purl.uniprot.org/uniprot/E8N5I8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/926569:ANT_RS00260 ^@ http://purl.uniprot.org/uniprot/E8MYE2 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/926569:ANT_RS12005 ^@ http://purl.uniprot.org/uniprot/E8MYV0 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/926569:ANT_RS06050 ^@ http://purl.uniprot.org/uniprot/E8N477 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05770 ^@ http://purl.uniprot.org/uniprot/E8N422 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/926569:ANT_RS03930 ^@ http://purl.uniprot.org/uniprot/E8N2L4 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/926569:ANT_RS02100 ^@ http://purl.uniprot.org/uniprot/E8N0R0 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/926569:ANT_RS07715 ^@ http://purl.uniprot.org/uniprot/E8N556 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/926569:ANT_RS00080 ^@ http://purl.uniprot.org/uniprot/E8MYA6 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/926569:ANT_RS17715 ^@ http://purl.uniprot.org/uniprot/E8MYQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS15250 ^@ http://purl.uniprot.org/uniprot/E8N2T3 ^@ Similarity ^@ Belongs to the ycf81 family. http://togogenome.org/gene/926569:ANT_RS09640 ^@ http://purl.uniprot.org/uniprot/E8N685 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/926569:ANT_RS01750 ^@ http://purl.uniprot.org/uniprot/E8N052 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/926569:ANT_RS01435 ^@ http://purl.uniprot.org/uniprot/E8MZY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/926569:ANT_RS12720 ^@ http://purl.uniprot.org/uniprot/E8MZN0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.|||Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926569:ANT_RS08105 ^@ http://purl.uniprot.org/uniprot/E8N5D1 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/926569:ANT_RS04065 ^@ http://purl.uniprot.org/uniprot/E8N2P1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 39 family. http://togogenome.org/gene/926569:ANT_RS10000 ^@ http://purl.uniprot.org/uniprot/E8MXE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS05045 ^@ http://purl.uniprot.org/uniprot/E8N3N0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/926569:ANT_RS11535 ^@ http://purl.uniprot.org/uniprot/E8MYK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/926569:ANT_RS06910 ^@ http://purl.uniprot.org/uniprot/E8N4P4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/926569:ANT_RS01340 ^@ http://purl.uniprot.org/uniprot/E8MZW9 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/926569:ANT_RS02960 ^@ http://purl.uniprot.org/uniprot/E8N1M4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/926569:ANT_RS01120 ^@ http://purl.uniprot.org/uniprot/E8MZB6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/926569:ANT_RS07305 ^@ http://purl.uniprot.org/uniprot/E8N4X3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. http://togogenome.org/gene/926569:ANT_RS02260 ^@ http://purl.uniprot.org/uniprot/E8N0U3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/926569:ANT_RS08335 ^@ http://purl.uniprot.org/uniprot/E8N5H4 ^@ Cofactor|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily.|||Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/926569:ANT_RS13290 ^@ http://purl.uniprot.org/uniprot/E8N0E3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/926569:ANT_RS06765 ^@ http://purl.uniprot.org/uniprot/E8N4M0 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/926569:ANT_RS04110 ^@ http://purl.uniprot.org/uniprot/E8N2Q0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/926569:ANT_RS00930 ^@ http://purl.uniprot.org/uniprot/E8MZ74 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/926569:ANT_RS09510 ^@ http://purl.uniprot.org/uniprot/E8N659 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/926569:ANT_RS05030 ^@ http://purl.uniprot.org/uniprot/E8N3M7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/926569:ANT_RS08115 ^@ http://purl.uniprot.org/uniprot/E8N5D3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by fructose 1,6-bisphosphate (FBP).|||Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS04470 ^@ http://purl.uniprot.org/uniprot/E8N3B3 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/926569:ANT_RS11725 ^@ http://purl.uniprot.org/uniprot/E8MYN8 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/926569:ANT_RS00500 ^@ http://purl.uniprot.org/uniprot/E8MYZ1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/926569:ANT_RS15035 ^@ http://purl.uniprot.org/uniprot/E8N293 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/926569:ANT_RS10345 ^@ http://purl.uniprot.org/uniprot/E8MXL4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/926569:ANT_RS04200 ^@ http://purl.uniprot.org/uniprot/E8N360 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS01970 ^@ http://purl.uniprot.org/uniprot/E8N0N4 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/926569:ANT_RS04460 ^@ http://purl.uniprot.org/uniprot/E8N3B1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/926569:ANT_RS01620 ^@ http://purl.uniprot.org/uniprot/E8N026 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/926569:ANT_RS14385 ^@ http://purl.uniprot.org/uniprot/E8N1W5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/926569:ANT_RS08275 ^@ http://purl.uniprot.org/uniprot/E8N5G3 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/926569:ANT_RS05275 ^@ http://purl.uniprot.org/uniprot/E8N3S7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/926569:ANT_RS06210 ^@ http://purl.uniprot.org/uniprot/E8N4A9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. LysZ subfamily.|||Catalyzes the phosphorylation of LysW-gamma-alpha-aminoadipate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS11365 ^@ http://purl.uniprot.org/uniprot/E8MY71 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS06570 ^@ http://purl.uniprot.org/uniprot/E8N4I0 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/926569:ANT_RS02595 ^@ http://purl.uniprot.org/uniprot/E8N112 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/926569:ANT_RS11375 ^@ http://purl.uniprot.org/uniprot/E8MY73 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/926569:ANT_RS03145 ^@ http://purl.uniprot.org/uniprot/E8N1Q9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/926569:ANT_RS11190 ^@ http://purl.uniprot.org/uniprot/E8MY36 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/926569:ANT_RS05735 ^@ http://purl.uniprot.org/uniprot/E8N415 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS00695 ^@ http://purl.uniprot.org/uniprot/E8MZ30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS07725 ^@ http://purl.uniprot.org/uniprot/E8N558 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/926569:ANT_RS05075 ^@ http://purl.uniprot.org/uniprot/E8N3N6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/926569:ANT_RS03535 ^@ http://purl.uniprot.org/uniprot/E8N2D6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/926569:ANT_RS12665 ^@ http://purl.uniprot.org/uniprot/E8MZL9 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS16135 ^@ http://purl.uniprot.org/uniprot/E8N3L3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05990 ^@ http://purl.uniprot.org/uniprot/E8N464 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926569:ANT_RS12365 ^@ http://purl.uniprot.org/uniprot/E8MZG0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/926569:ANT_RS00830 ^@ http://purl.uniprot.org/uniprot/E8MZ57 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/926569:ANT_RS05005 ^@ http://purl.uniprot.org/uniprot/E8N3M2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/926569:ANT_RS01640 ^@ http://purl.uniprot.org/uniprot/E8N030 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/926569:ANT_RS05095 ^@ http://purl.uniprot.org/uniprot/E8N3P0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/926569:ANT_RS04280 ^@ http://purl.uniprot.org/uniprot/E8N376 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS10480 ^@ http://purl.uniprot.org/uniprot/E8MXP1 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/926569:ANT_RS11125 ^@ http://purl.uniprot.org/uniprot/E8MY26 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS12010 ^@ http://purl.uniprot.org/uniprot/E8MYV1 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/926569:ANT_RS11575 ^@ http://purl.uniprot.org/uniprot/E8MYK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/926569:ANT_RS08440 ^@ http://purl.uniprot.org/uniprot/E8N5J5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/926569:ANT_RS14615 ^@ http://purl.uniprot.org/uniprot/E8N211 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/926569:ANT_RS08505 ^@ http://purl.uniprot.org/uniprot/E8N5K8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/926569:ANT_RS03755 ^@ http://purl.uniprot.org/uniprot/E8N2H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS06625 ^@ http://purl.uniprot.org/uniprot/E8N4J1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/926569:ANT_RS09320 ^@ http://purl.uniprot.org/uniprot/E8N621 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS10565 ^@ http://purl.uniprot.org/uniprot/E8MXR0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS14635 ^@ http://purl.uniprot.org/uniprot/E8N215 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/926569:ANT_RS06515 ^@ http://purl.uniprot.org/uniprot/E8N4H1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS13380 ^@ http://purl.uniprot.org/uniprot/E8N0G2 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/926569:ANT_RS02890 ^@ http://purl.uniprot.org/uniprot/E8N1L0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the OadG family.|||Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS13170 ^@ http://purl.uniprot.org/uniprot/E8N0C0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS03410 ^@ http://purl.uniprot.org/uniprot/E8N1W3 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/926569:ANT_RS13980 ^@ http://purl.uniprot.org/uniprot/E8N187 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/926569:ANT_RS01915 ^@ http://purl.uniprot.org/uniprot/E8N0M3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/926569:ANT_RS13445 ^@ http://purl.uniprot.org/uniprot/E8N0H6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/926569:ANT_RS02035 ^@ http://purl.uniprot.org/uniprot/E8N0P7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/926569:ANT_RS14080 ^@ http://purl.uniprot.org/uniprot/E8N1A7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS08380 ^@ http://purl.uniprot.org/uniprot/E8N5I3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS06750 ^@ http://purl.uniprot.org/uniprot/E8N4L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane http://togogenome.org/gene/926569:ANT_RS15245 ^@ http://purl.uniprot.org/uniprot/E8N2T2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/926569:ANT_RS02615 ^@ http://purl.uniprot.org/uniprot/E8N116 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/926569:ANT_RS01280 ^@ http://purl.uniprot.org/uniprot/E8MZV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS07990 ^@ http://purl.uniprot.org/uniprot/E8N5A8 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/926569:ANT_RS11040 ^@ http://purl.uniprot.org/uniprot/E8MY09 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/926569:ANT_RS08925 ^@ http://purl.uniprot.org/uniprot/E8N5U2 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/926569:ANT_RS00405 ^@ http://purl.uniprot.org/uniprot/E8MYH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS10975 ^@ http://purl.uniprot.org/uniprot/E8MXZ5 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/926569:ANT_RS13770 ^@ http://purl.uniprot.org/uniprot/E8N146 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrC/TusE family.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS04525 ^@ http://purl.uniprot.org/uniprot/E8N3C4 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/926569:ANT_RS09325 ^@ http://purl.uniprot.org/uniprot/E8N622 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/926569:ANT_RS03670 ^@ http://purl.uniprot.org/uniprot/E8N2G2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.|||Cell inner membrane|||Mediates magnesium influx to the cytosol.|||Membrane http://togogenome.org/gene/926569:ANT_RS13820 ^@ http://purl.uniprot.org/uniprot/E8N156 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/926569:ANT_RS02450 ^@ http://purl.uniprot.org/uniprot/E8N0Y2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS16340 ^@ http://purl.uniprot.org/uniprot/E8N5S2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/926569:ANT_RS16060 ^@ http://purl.uniprot.org/uniprot/E8N384 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS14965 ^@ http://purl.uniprot.org/uniprot/E8N279 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/926569:ANT_RS13075 ^@ http://purl.uniprot.org/uniprot/E8N0A1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/926569:ANT_RS14655 ^@ http://purl.uniprot.org/uniprot/E8N220 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/926569:ANT_RS00045 ^@ http://purl.uniprot.org/uniprot/E8MY98 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/926569:ANT_RS04800 ^@ http://purl.uniprot.org/uniprot/E8N3I1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05085 ^@ http://purl.uniprot.org/uniprot/E8N3N8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/926569:ANT_RS00150 ^@ http://purl.uniprot.org/uniprot/E8MYC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS13795 ^@ http://purl.uniprot.org/uniprot/E8N151 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS11680 ^@ http://purl.uniprot.org/uniprot/E8MYM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS03725 ^@ http://purl.uniprot.org/uniprot/E8N2H3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS11855 ^@ http://purl.uniprot.org/uniprot/E8MYR5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/926569:ANT_RS17840 ^@ http://purl.uniprot.org/uniprot/E8N567 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/926569:ANT_RS12465 ^@ http://purl.uniprot.org/uniprot/E8MZH9 ^@ Similarity ^@ Belongs to the radical SAM superfamily. KamA family. http://togogenome.org/gene/926569:ANT_RS01765 ^@ http://purl.uniprot.org/uniprot/E8N055 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/926569:ANT_RS09255 ^@ http://purl.uniprot.org/uniprot/E8N608 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/926569:ANT_RS00655 ^@ http://purl.uniprot.org/uniprot/E8MZ22 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS11840 ^@ http://purl.uniprot.org/uniprot/E8MYR2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/926569:ANT_RS11655 ^@ http://purl.uniprot.org/uniprot/E8MYM4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS02670 ^@ http://purl.uniprot.org/uniprot/E8N127 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. http://togogenome.org/gene/926569:ANT_RS04730 ^@ http://purl.uniprot.org/uniprot/E8N3G7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/926569:ANT_RS04985 ^@ http://purl.uniprot.org/uniprot/E8N3L8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/926569:ANT_RS00540 ^@ http://purl.uniprot.org/uniprot/E8MZ00 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926569:ANT_RS04840 ^@ http://purl.uniprot.org/uniprot/E8N3I9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/926569:ANT_RS14410 ^@ http://purl.uniprot.org/uniprot/E8N1X0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/926569:ANT_RS13540 ^@ http://purl.uniprot.org/uniprot/E8N0J6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS06610 ^@ http://purl.uniprot.org/uniprot/E8N4I8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/926569:ANT_RS10765 ^@ http://purl.uniprot.org/uniprot/E8MXV2 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/926569:ANT_RS05260 ^@ http://purl.uniprot.org/uniprot/E8N3S4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||In the C-terminal section; belongs to the ATPase delta chain family.|||In the N-terminal section; belongs to the ATPase B chain family.|||Membrane|||This fusion protein includes a component of the F(0) channel (subunit b) and of the F(1) subunit (subunit delta). Two copies of subunit b and one of delta together form the peripheral 'stator' stalk which links F(1) to F(0). http://togogenome.org/gene/926569:ANT_RS04815 ^@ http://purl.uniprot.org/uniprot/E8N3I4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/926569:ANT_RS09080 ^@ http://purl.uniprot.org/uniprot/E8N5X3 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/926569:ANT_RS14405 ^@ http://purl.uniprot.org/uniprot/E8N1W9 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/926569:ANT_RS09540 ^@ http://purl.uniprot.org/uniprot/E8N3M2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/926569:ANT_RS01500 ^@ http://purl.uniprot.org/uniprot/E8N002 ^@ Similarity ^@ Belongs to the dihydropyrimidine dehydrogenase family. http://togogenome.org/gene/926569:ANT_RS02515 ^@ http://purl.uniprot.org/uniprot/E8N0Z5 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS03170 ^@ http://purl.uniprot.org/uniprot/E8N1R4 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/926569:ANT_RS09605 ^@ http://purl.uniprot.org/uniprot/E8N676 ^@ Similarity ^@ Belongs to the CbxX/CfxQ family. http://togogenome.org/gene/926569:ANT_RS09500 ^@ http://purl.uniprot.org/uniprot/E8N657 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/926569:ANT_RS13295 ^@ http://purl.uniprot.org/uniprot/E8N0E4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/926569:ANT_RS07800 ^@ http://purl.uniprot.org/uniprot/E8N573 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/926569:ANT_RS13815 ^@ http://purl.uniprot.org/uniprot/E8N155 ^@ Function|||Similarity ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane. http://togogenome.org/gene/926569:ANT_RS05000 ^@ http://purl.uniprot.org/uniprot/E8N3M1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS06220 ^@ http://purl.uniprot.org/uniprot/E8N4B1 ^@ Similarity ^@ Belongs to the RimK family. LysX subfamily. http://togogenome.org/gene/926569:ANT_RS03665 ^@ http://purl.uniprot.org/uniprot/E8N2G0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926569:ANT_RS02990 ^@ http://purl.uniprot.org/uniprot/E8N1N0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05405 ^@ http://purl.uniprot.org/uniprot/E8N3V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS14455 ^@ http://purl.uniprot.org/uniprot/E8N1X9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS11430 ^@ http://purl.uniprot.org/uniprot/E8MY84 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpB RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpA.|||Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS02090 ^@ http://purl.uniprot.org/uniprot/E8N0Q8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS08885 ^@ http://purl.uniprot.org/uniprot/E8N5T4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926569:ANT_RS09950 ^@ http://purl.uniprot.org/uniprot/E8N6F2 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/926569:ANT_RS11100 ^@ http://purl.uniprot.org/uniprot/E8MY22 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/926569:ANT_RS12485 ^@ http://purl.uniprot.org/uniprot/E8MZI3 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/926569:ANT_RS07470 ^@ http://purl.uniprot.org/uniprot/E8N506 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS01250 ^@ http://purl.uniprot.org/uniprot/E8MZV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/926569:ANT_RS03495 ^@ http://purl.uniprot.org/uniprot/E8N2C9 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/926569:ANT_RS06205 ^@ http://purl.uniprot.org/uniprot/E8N4A8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926569:ANT_RS14450 ^@ http://purl.uniprot.org/uniprot/E8N1X8 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/926569:ANT_RS00680 ^@ http://purl.uniprot.org/uniprot/E8MZ27 ^@ Caution|||Function|||Similarity ^@ Belongs to the RecR family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/926569:ANT_RS07145 ^@ http://purl.uniprot.org/uniprot/E8N4U2 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/926569:ANT_RS09075 ^@ http://purl.uniprot.org/uniprot/E8N5X2 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926569:ANT_RS10560 ^@ http://purl.uniprot.org/uniprot/E8MXQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS06085 ^@ http://purl.uniprot.org/uniprot/E8N484 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/926569:ANT_RS09060 ^@ http://purl.uniprot.org/uniprot/E8N5W9 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/926569:ANT_RS02490 ^@ http://purl.uniprot.org/uniprot/E8N0Z0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/926569:ANT_RS09900 ^@ http://purl.uniprot.org/uniprot/E8N6E1 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/926569:ANT_RS11660 ^@ http://purl.uniprot.org/uniprot/E8MYM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS13090 ^@ http://purl.uniprot.org/uniprot/E8N0A4 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/926569:ANT_RS12370 ^@ http://purl.uniprot.org/uniprot/E8MZG1 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/926569:ANT_RS01655 ^@ http://purl.uniprot.org/uniprot/E8N033 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926569:ANT_RS01660 ^@ http://purl.uniprot.org/uniprot/E8N034 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926569:ANT_RS17940 ^@ http://purl.uniprot.org/uniprot/E8N2X2 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/926569:ANT_RS05020 ^@ http://purl.uniprot.org/uniprot/E8N3M5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/926569:ANT_RS04095 ^@ http://purl.uniprot.org/uniprot/E8N2P7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/926569:ANT_RS13500 ^@ http://purl.uniprot.org/uniprot/E8N0I7 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/926569:ANT_RS13605 ^@ http://purl.uniprot.org/uniprot/E8N0K8 ^@ Similarity ^@ Belongs to the argonaute family. Long pAgo subfamily. http://togogenome.org/gene/926569:ANT_RS03890 ^@ http://purl.uniprot.org/uniprot/E8N2K6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS07995 ^@ http://purl.uniprot.org/uniprot/E8N5A9 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/926569:ANT_RS10415 ^@ http://purl.uniprot.org/uniprot/E8MXM8 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/926569:ANT_RS07070 ^@ http://purl.uniprot.org/uniprot/E8N4S6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS02110 ^@ http://purl.uniprot.org/uniprot/E8N0R2 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/926569:ANT_RS05530 ^@ http://purl.uniprot.org/uniprot/E8N3X5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS02985 ^@ http://purl.uniprot.org/uniprot/E8N1M9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS04490 ^@ http://purl.uniprot.org/uniprot/E8N3B7 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/926569:ANT_RS04915 ^@ http://purl.uniprot.org/uniprot/E8N3K4 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/926569:ANT_RS05515 ^@ http://purl.uniprot.org/uniprot/E8N3X2 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/926569:ANT_RS14210 ^@ http://purl.uniprot.org/uniprot/E8N1D3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRISPR system Cmr5 family.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS15415 ^@ http://purl.uniprot.org/uniprot/E8N2W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS05360 ^@ http://purl.uniprot.org/uniprot/E8N3U2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS03720 ^@ http://purl.uniprot.org/uniprot/E8N2H2 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/926569:ANT_RS15175 ^@ http://purl.uniprot.org/uniprot/E8N2R9 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/926569:ANT_RS06270 ^@ http://purl.uniprot.org/uniprot/E8N4C2 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/926569:ANT_RS06325 ^@ http://purl.uniprot.org/uniprot/E8N4D2 ^@ Similarity|||Subunit ^@ Belongs to the FPG family.|||Monomer. http://togogenome.org/gene/926569:ANT_RS13285 ^@ http://purl.uniprot.org/uniprot/E8N0E2 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/926569:ANT_RS14675 ^@ http://purl.uniprot.org/uniprot/E8N224 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/926569:ANT_RS08480 ^@ http://purl.uniprot.org/uniprot/E8N5K3 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/926569:ANT_RS14925 ^@ http://purl.uniprot.org/uniprot/E8N272 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/926569:ANT_RS14370 ^@ http://purl.uniprot.org/uniprot/E8N1G5 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/926569:ANT_RS11260 ^@ http://purl.uniprot.org/uniprot/E8MY50 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/926569:ANT_RS05395 ^@ http://purl.uniprot.org/uniprot/E8N3U9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05610 ^@ http://purl.uniprot.org/uniprot/E8N3Z1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.|||Golgi apparatus|||Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.|||In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.|||In the N-terminal section; belongs to the formiminotransferase family.|||centriole http://togogenome.org/gene/926569:ANT_RS02900 ^@ http://purl.uniprot.org/uniprot/E8N1L2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS04595 ^@ http://purl.uniprot.org/uniprot/E8N3D8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS07095 ^@ http://purl.uniprot.org/uniprot/E8N4T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS10105 ^@ http://purl.uniprot.org/uniprot/E8MXG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS06000 ^@ http://purl.uniprot.org/uniprot/E8N466 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/926569:ANT_RS14850 ^@ http://purl.uniprot.org/uniprot/E8N257 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/926569:ANT_RS09570 ^@ http://purl.uniprot.org/uniprot/E8N667 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/926569:ANT_RS01035 ^@ http://purl.uniprot.org/uniprot/E8MZ95 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/926569:ANT_RS05055 ^@ http://purl.uniprot.org/uniprot/E8N3N2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/926569:ANT_RS05205 ^@ http://purl.uniprot.org/uniprot/E8N3R3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926569:ANT_RS15700 ^@ http://purl.uniprot.org/uniprot/E8N324 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS09010 ^@ http://purl.uniprot.org/uniprot/E8N5V9 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/926569:ANT_RS02785 ^@ http://purl.uniprot.org/uniprot/E8N1J0 ^@ Subcellular Location Annotation|||Subunit ^@ Homodimer.|||Secreted http://togogenome.org/gene/926569:ANT_RS04180 ^@ http://purl.uniprot.org/uniprot/E8N356 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/926569:ANT_RS04980 ^@ http://purl.uniprot.org/uniprot/E8N3L7 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/926569:ANT_RS02975 ^@ http://purl.uniprot.org/uniprot/E8N1M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS16835 ^@ http://purl.uniprot.org/uniprot/E8N6B7 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/926569:ANT_RS05510 ^@ http://purl.uniprot.org/uniprot/E8N3X1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS00285 ^@ http://purl.uniprot.org/uniprot/E8MYE8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/926569:ANT_RS03140 ^@ http://purl.uniprot.org/uniprot/E8N1Q8 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS12650 ^@ http://purl.uniprot.org/uniprot/E8MZL6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS17625 ^@ http://purl.uniprot.org/uniprot/E8N2S5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/926569:ANT_RS04195 ^@ http://purl.uniprot.org/uniprot/E8N359 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/926569:ANT_RS14155 ^@ http://purl.uniprot.org/uniprot/E8N1C2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/926569:ANT_RS15595 ^@ http://purl.uniprot.org/uniprot/E8N302 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/926569:ANT_RS05090 ^@ http://purl.uniprot.org/uniprot/E8N3N9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/926569:ANT_RS01715 ^@ http://purl.uniprot.org/uniprot/E8N045 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/926569:ANT_RS05875 ^@ http://purl.uniprot.org/uniprot/E8N443 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/926569:ANT_RS10985 ^@ http://purl.uniprot.org/uniprot/E8MXZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS11720 ^@ http://purl.uniprot.org/uniprot/E8MYN7 ^@ Caution|||Function|||Similarity ^@ Belongs to the NrdR family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/926569:ANT_RS00690 ^@ http://purl.uniprot.org/uniprot/E8MZ29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS13465 ^@ http://purl.uniprot.org/uniprot/E8N0I0 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/926569:ANT_RS02000 ^@ http://purl.uniprot.org/uniprot/E8N0P0 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/926569:ANT_RS05705 ^@ http://purl.uniprot.org/uniprot/E8N409 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/926569:ANT_RS16765 ^@ http://purl.uniprot.org/uniprot/E8MZB8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/926569:ANT_RS08665 ^@ http://purl.uniprot.org/uniprot/E8N5P3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/926569:ANT_RS15505 ^@ http://purl.uniprot.org/uniprot/E8N2Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/926569:ANT_RS03550 ^@ http://purl.uniprot.org/uniprot/E8N2D9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS11045 ^@ http://purl.uniprot.org/uniprot/E8MY10 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/926569:ANT_RS07050 ^@ http://purl.uniprot.org/uniprot/E8N4S2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/926569:ANT_RS08785 ^@ http://purl.uniprot.org/uniprot/E8N5R7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/926569:ANT_RS08195 ^@ http://purl.uniprot.org/uniprot/E8N5E7 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926569:ANT_RS05480 ^@ http://purl.uniprot.org/uniprot/E8N3W5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS02980 ^@ http://purl.uniprot.org/uniprot/E8N1M8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS06140 ^@ http://purl.uniprot.org/uniprot/E8N494 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/926569:ANT_RS12815 ^@ http://purl.uniprot.org/uniprot/E8MZP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS09920 ^@ http://purl.uniprot.org/uniprot/E8N6E5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/926569:ANT_RS06920 ^@ http://purl.uniprot.org/uniprot/E8N4P6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/926569:ANT_RS06455 ^@ http://purl.uniprot.org/uniprot/E8N4F9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS01430 ^@ http://purl.uniprot.org/uniprot/E8MZY7 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/926569:ANT_RS02230 ^@ http://purl.uniprot.org/uniprot/E8N0T6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M4 family.|||Extracellular zinc metalloprotease.|||Secreted http://togogenome.org/gene/926569:ANT_RS16780 ^@ http://purl.uniprot.org/uniprot/E8N3G8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS02385 ^@ http://purl.uniprot.org/uniprot/E8N0W9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.|||Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.|||Homotetramer; dimer of dimers.|||Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate. http://togogenome.org/gene/926569:ANT_RS07165 ^@ http://purl.uniprot.org/uniprot/E8N4U6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/926569:ANT_RS02695 ^@ http://purl.uniprot.org/uniprot/E8N1H2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbsD / FucU family. RbsD subfamily.|||Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.|||Cytoplasm|||Homodecamer. http://togogenome.org/gene/926569:ANT_RS06730 ^@ http://purl.uniprot.org/uniprot/E8N4L3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/926569:ANT_RS09150 ^@ http://purl.uniprot.org/uniprot/E8N5Y8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS10020 ^@ http://purl.uniprot.org/uniprot/E8MXE9 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/926569:ANT_RS05135 ^@ http://purl.uniprot.org/uniprot/E8N3P9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/926569:ANT_RS12570 ^@ http://purl.uniprot.org/uniprot/E8MZK0 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/926569:ANT_RS12745 ^@ http://purl.uniprot.org/uniprot/E8MZN5 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/926569:ANT_RS05365 ^@ http://purl.uniprot.org/uniprot/E8N3U3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS06285 ^@ http://purl.uniprot.org/uniprot/E8N4C5 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/926569:ANT_RS01315 ^@ http://purl.uniprot.org/uniprot/E8MZW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS02620 ^@ http://purl.uniprot.org/uniprot/E8N117 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS16110 ^@ http://purl.uniprot.org/uniprot/E8N3I5 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/926569:ANT_RS09515 ^@ http://purl.uniprot.org/uniprot/E8N660 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/926569:ANT_RS00250 ^@ http://purl.uniprot.org/uniprot/E8MYE0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS02995 ^@ http://purl.uniprot.org/uniprot/E8N1N1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS14900 ^@ http://purl.uniprot.org/uniprot/E8N267 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/926569:ANT_RS13100 ^@ http://purl.uniprot.org/uniprot/E8N0A6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/926569:ANT_RS01505 ^@ http://purl.uniprot.org/uniprot/E8N003 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/926569:ANT_RS04005 ^@ http://purl.uniprot.org/uniprot/E8N2N0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 42 family. http://togogenome.org/gene/926569:ANT_RS13485 ^@ http://purl.uniprot.org/uniprot/E8N0I4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS11330 ^@ http://purl.uniprot.org/uniprot/E8MY64 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS12320 ^@ http://purl.uniprot.org/uniprot/E8MZF1 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/926569:ANT_RS06245 ^@ http://purl.uniprot.org/uniprot/E8N4B7 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/926569:ANT_RS01215 ^@ http://purl.uniprot.org/uniprot/E8MZU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05615 ^@ http://purl.uniprot.org/uniprot/E8N3Z2 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/926569:ANT_RS02940 ^@ http://purl.uniprot.org/uniprot/E8N1M0 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/926569:ANT_RS07315 ^@ http://purl.uniprot.org/uniprot/E8N4X5 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/926569:ANT_RS04610 ^@ http://purl.uniprot.org/uniprot/E8N3E1 ^@ Similarity ^@ Belongs to the adenylyl cyclase class-3 family. http://togogenome.org/gene/926569:ANT_RS07960 ^@ http://purl.uniprot.org/uniprot/E8N5A2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS15620 ^@ http://purl.uniprot.org/uniprot/E8N307 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS04410 ^@ http://purl.uniprot.org/uniprot/E8N3A1 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/926569:ANT_RS00130 ^@ http://purl.uniprot.org/uniprot/E8MYB6 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/926569:ANT_RS13660 ^@ http://purl.uniprot.org/uniprot/E8N0L8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/926569:ANT_RS06130 ^@ http://purl.uniprot.org/uniprot/E8N492 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/926569:ANT_RS10505 ^@ http://purl.uniprot.org/uniprot/E8MXP6 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/926569:ANT_RS07370 ^@ http://purl.uniprot.org/uniprot/E8N4Y6 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/926569:ANT_RS13910 ^@ http://purl.uniprot.org/uniprot/E8N174 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS07520 ^@ http://purl.uniprot.org/uniprot/E8N516 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS04790 ^@ http://purl.uniprot.org/uniprot/E8N3H9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/926569:ANT_RS10550 ^@ http://purl.uniprot.org/uniprot/E8MXQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/926569:ANT_RS12495 ^@ http://purl.uniprot.org/uniprot/E8MZI5 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/926569:ANT_RS03005 ^@ http://purl.uniprot.org/uniprot/E8N1N3 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/926569:ANT_RS11390 ^@ http://purl.uniprot.org/uniprot/E8MY76 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/926569:ANT_RS02950 ^@ http://purl.uniprot.org/uniprot/E8N1M2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS03245 ^@ http://purl.uniprot.org/uniprot/E8N1S9 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/926569:ANT_RS01040 ^@ http://purl.uniprot.org/uniprot/E8MZ96 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/926569:ANT_RS08930 ^@ http://purl.uniprot.org/uniprot/E8N5U3 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/926569:ANT_RS05215 ^@ http://purl.uniprot.org/uniprot/E8N3R5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS00715 ^@ http://purl.uniprot.org/uniprot/E8MZ34 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/926569:ANT_RS01645 ^@ http://purl.uniprot.org/uniprot/E8N031 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/926569:ANT_RS01310 ^@ http://purl.uniprot.org/uniprot/E8MZW3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/926569:ANT_RS04995 ^@ http://purl.uniprot.org/uniprot/E8N3M0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/926569:ANT_RS08410 ^@ http://purl.uniprot.org/uniprot/E8N5I9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/926569:ANT_RS03695 ^@ http://purl.uniprot.org/uniprot/E8N2G7 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/926569:ANT_RS04495 ^@ http://purl.uniprot.org/uniprot/E8N3B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS00920 ^@ http://purl.uniprot.org/uniprot/E8MZ71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS01815 ^@ http://purl.uniprot.org/uniprot/E8N065 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/926569:ANT_RS02335 ^@ http://purl.uniprot.org/uniprot/E8N0V9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS10365 ^@ http://purl.uniprot.org/uniprot/E8MXL8 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/926569:ANT_RS03525 ^@ http://purl.uniprot.org/uniprot/E8N2D3 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/926569:ANT_RS05420 ^@ http://purl.uniprot.org/uniprot/E8N3V4 ^@ Similarity ^@ Belongs to the peptidase C69 family. http://togogenome.org/gene/926569:ANT_RS07495 ^@ http://purl.uniprot.org/uniprot/E8N511 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/926569:ANT_RS12905 ^@ http://purl.uniprot.org/uniprot/E8MZR7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS05070 ^@ http://purl.uniprot.org/uniprot/E8N3N5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/926569:ANT_RS11785 ^@ http://purl.uniprot.org/uniprot/E8MYQ1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS15730 ^@ http://purl.uniprot.org/uniprot/E8N329 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/926569:ANT_RS14255 ^@ http://purl.uniprot.org/uniprot/E8N1E2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926569:ANT_RS00730 ^@ http://purl.uniprot.org/uniprot/E8MZ37 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/926569:ANT_RS04895 ^@ http://purl.uniprot.org/uniprot/E8N3K0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/926569:ANT_RS08515 ^@ http://purl.uniprot.org/uniprot/E8N5L1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/926569:ANT_RS09955 ^@ http://purl.uniprot.org/uniprot/E8N6F3 ^@ Similarity ^@ Belongs to the diphosphomevalonate decarboxylase family. http://togogenome.org/gene/926569:ANT_RS08595 ^@ http://purl.uniprot.org/uniprot/E8N5M8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS11665 ^@ http://purl.uniprot.org/uniprot/E8MYM6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS05300 ^@ http://purl.uniprot.org/uniprot/E8N3T2 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/926569:ANT_RS05155 ^@ http://purl.uniprot.org/uniprot/E8N3Q3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS08095 ^@ http://purl.uniprot.org/uniprot/E8N5C9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/926569:ANT_RS09045 ^@ http://purl.uniprot.org/uniprot/E8N5W6 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926569:ANT_RS05120 ^@ http://purl.uniprot.org/uniprot/E8N3P5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/926569:ANT_RS14340 ^@ http://purl.uniprot.org/uniprot/E8N1G0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS08330 ^@ http://purl.uniprot.org/uniprot/E8N5H3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/926569:ANT_RS10490 ^@ http://purl.uniprot.org/uniprot/E8MXP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS14620 ^@ http://purl.uniprot.org/uniprot/E8N212 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/926569:ANT_RS15880 ^@ http://purl.uniprot.org/uniprot/E8MZ25 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/926569:ANT_RS05805 ^@ http://purl.uniprot.org/uniprot/E8N429 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/926569:ANT_RS10025 ^@ http://purl.uniprot.org/uniprot/E8MXF0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS11280 ^@ http://purl.uniprot.org/uniprot/E8MY54 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/926569:ANT_RS01840 ^@ http://purl.uniprot.org/uniprot/E8N070 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nurim family.|||Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).|||Membrane http://togogenome.org/gene/926569:ANT_RS16195 ^@ http://purl.uniprot.org/uniprot/E8N4F8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS04390 ^@ http://purl.uniprot.org/uniprot/E8N397 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS08050 ^@ http://purl.uniprot.org/uniprot/E8N5C0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS07085 ^@ http://purl.uniprot.org/uniprot/E8N4S9 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/926569:ANT_RS15410 ^@ http://purl.uniprot.org/uniprot/E8N2W6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/926569:ANT_RS14095 ^@ http://purl.uniprot.org/uniprot/E8N1B0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/926569:ANT_RS08425 ^@ http://purl.uniprot.org/uniprot/E8N5J2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. C-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/926569:ANT_RS07405 ^@ http://purl.uniprot.org/uniprot/E8N4Z3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/926569:ANT_RS05435 ^@ http://purl.uniprot.org/uniprot/E8N3V7 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/926569:ANT_RS12215 ^@ http://purl.uniprot.org/uniprot/E8MZD1 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm5 family.|||This subunit might be involved in maturation of a crRNA intermediate to its mature form. http://togogenome.org/gene/926569:ANT_RS06890 ^@ http://purl.uniprot.org/uniprot/E8N4P0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/926569:ANT_RS07080 ^@ http://purl.uniprot.org/uniprot/E8N4S8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/926569:ANT_RS06605 ^@ http://purl.uniprot.org/uniprot/E8N4I7 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/926569:ANT_RS11435 ^@ http://purl.uniprot.org/uniprot/E8MY85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/926569:ANT_RS00625 ^@ http://purl.uniprot.org/uniprot/E8MZ16 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/926569:ANT_RS12630 ^@ http://purl.uniprot.org/uniprot/E8MZL2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/926569:ANT_RS00290 ^@ http://purl.uniprot.org/uniprot/E8MYE9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/926569:ANT_RS07655 ^@ http://purl.uniprot.org/uniprot/E8N542 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/926569:ANT_RS02630 ^@ http://purl.uniprot.org/uniprot/E8N119 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/926569:ANT_RS05255 ^@ http://purl.uniprot.org/uniprot/E8N3S3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/926569:ANT_RS12480 ^@ http://purl.uniprot.org/uniprot/E8MZI2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/926569:ANT_RS10260 ^@ http://purl.uniprot.org/uniprot/E8MXJ6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926569:ANT_RS17730 ^@ http://purl.uniprot.org/uniprot/E8MZH3 ^@ Cofactor ^@ Binds 2 magnesium ions per subunit. http://togogenome.org/gene/926569:ANT_RS09810 ^@ http://purl.uniprot.org/uniprot/E8N6C2 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/926569:ANT_RS06390 ^@ http://purl.uniprot.org/uniprot/E8N4E4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926569:ANT_RS06185 ^@ http://purl.uniprot.org/uniprot/E8N4A3 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/926569:ANT_RS10465 ^@ http://purl.uniprot.org/uniprot/E8MXN7 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/926569:ANT_RS09985 ^@ http://purl.uniprot.org/uniprot/E8MXE2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/926569:ANT_RS03125 ^@ http://purl.uniprot.org/uniprot/E8N1Q5 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/926569:ANT_RS03485 ^@ http://purl.uniprot.org/uniprot/E8N2C7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M32 family.|||Binds 1 zinc ion per subunit.|||Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. http://togogenome.org/gene/926569:ANT_RS04370 ^@ http://purl.uniprot.org/uniprot/E8N393 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/926569:ANT_RS03590 ^@ http://purl.uniprot.org/uniprot/E8N2E7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutB family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/926569:ANT_RS04400 ^@ http://purl.uniprot.org/uniprot/E8N399 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/926569:ANT_RS06105 ^@ http://purl.uniprot.org/uniprot/E8N488 ^@ Similarity ^@ Belongs to the citrate synthase family.