http://togogenome.org/gene/926571:NVIE_RS05590 ^@ http://purl.uniprot.org/uniprot/A0A060HFK6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS09765 ^@ http://purl.uniprot.org/uniprot/A0A060HRZ8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/926571:NVIE_RS01550 ^@ http://purl.uniprot.org/uniprot/A0A060HCQ3 ^@ Caution|||Function|||Similarity ^@ Belongs to the Nre family.|||Involved in DNA damage repair.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS01730 ^@ http://purl.uniprot.org/uniprot/A0A060HGS7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/926571:NVIE_RS07225 ^@ http://purl.uniprot.org/uniprot/A0A060HGI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/926571:NVIE_RS13855 ^@ http://purl.uniprot.org/uniprot/A0A060HUS2 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/926571:NVIE_RS13590 ^@ http://purl.uniprot.org/uniprot/A0A060HPQ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.|||Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure. http://togogenome.org/gene/926571:NVIE_RS02435 ^@ http://purl.uniprot.org/uniprot/A0A060HD85 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS02715 ^@ http://purl.uniprot.org/uniprot/A0A060HGP1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS14370 ^@ http://purl.uniprot.org/uniprot/A0A060HQ85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/926571:NVIE_RS02830 ^@ http://purl.uniprot.org/uniprot/A0A060HGS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.|||Cytoplasm http://togogenome.org/gene/926571:NVIE_RS11275 ^@ http://purl.uniprot.org/uniprot/A0A060HMA7 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/926571:NVIE_RS01385 ^@ http://purl.uniprot.org/uniprot/A0A060HLM5 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/926571:NVIE_RS07025 ^@ http://purl.uniprot.org/uniprot/A0A060HQ59 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/926571:NVIE_RS02540 ^@ http://purl.uniprot.org/uniprot/A0A060HH76 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/926571:NVIE_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A060HMH8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/926571:NVIE_RS11045 ^@ http://purl.uniprot.org/uniprot/A0A060HTY4 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.|||Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. http://togogenome.org/gene/926571:NVIE_RS05185 ^@ http://purl.uniprot.org/uniprot/A0A060HF83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS10020 ^@ http://purl.uniprot.org/uniprot/A0A060HT77 ^@ Similarity ^@ Belongs to the PstS family. http://togogenome.org/gene/926571:NVIE_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A060HHM1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS25 family. http://togogenome.org/gene/926571:NVIE_RS06740 ^@ http://purl.uniprot.org/uniprot/A0A060HJD1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecY/SEC61-alpha family.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/926571:NVIE_RS00695 ^@ http://purl.uniprot.org/uniprot/A0A060HG33 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).|||Belongs to the TDD superfamily. TSR3 family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS10535 ^@ http://purl.uniprot.org/uniprot/A0A060HTN5 ^@ Similarity|||Subunit ^@ Belongs to the HTP reductase family.|||Homodimer. http://togogenome.org/gene/926571:NVIE_RS14305 ^@ http://purl.uniprot.org/uniprot/A0A060HW67 ^@ Cofactor ^@ Binds 1 copper ion per subunit. http://togogenome.org/gene/926571:NVIE_RS10630 ^@ http://purl.uniprot.org/uniprot/A0A060HSP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/926571:NVIE_RS11545 ^@ http://purl.uniprot.org/uniprot/A0A060HU84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS13135 ^@ http://purl.uniprot.org/uniprot/A0A060HUB9 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/926571:NVIE_RS08530 ^@ http://purl.uniprot.org/uniprot/A0A060HLB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/926571:NVIE_RS06520 ^@ http://purl.uniprot.org/uniprot/A0A060HJX7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Part of the 30S ribosomal subunit.|||With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. http://togogenome.org/gene/926571:NVIE_RS11420 ^@ http://purl.uniprot.org/uniprot/A0A060HT36 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/926571:NVIE_RS03275 ^@ http://purl.uniprot.org/uniprot/A0A060HHV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/926571:NVIE_RS11290 ^@ http://purl.uniprot.org/uniprot/A0A060HT08 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926571:NVIE_RS08470 ^@ http://purl.uniprot.org/uniprot/A0A060HS70 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/926571:NVIE_RS07185 ^@ http://purl.uniprot.org/uniprot/A0A060HKA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/926571:NVIE_RS01890 ^@ http://purl.uniprot.org/uniprot/A0A060HG53 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/926571:NVIE_RS05680 ^@ http://purl.uniprot.org/uniprot/A0A060HIS0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/926571:NVIE_RS13270 ^@ http://purl.uniprot.org/uniprot/A0A060HVH8 ^@ Cofactor|||Function|||Miscellaneous|||Similarity ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/926571:NVIE_RS00770 ^@ http://purl.uniprot.org/uniprot/A0A060HL74 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/926571:NVIE_RS06500 ^@ http://purl.uniprot.org/uniprot/A0A060HPV1 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/926571:NVIE_RS04945 ^@ http://purl.uniprot.org/uniprot/A0A060HI72 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/926571:NVIE_RS05910 ^@ http://purl.uniprot.org/uniprot/A0A060HFS9 ^@ Similarity ^@ Belongs to the UPF0166 family. http://togogenome.org/gene/926571:NVIE_RS02520 ^@ http://purl.uniprot.org/uniprot/A0A060HMB0 ^@ Similarity ^@ Belongs to the peptidase T1A family. http://togogenome.org/gene/926571:NVIE_RS12340 ^@ http://purl.uniprot.org/uniprot/A0A060HNZ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/926571:NVIE_RS11220 ^@ http://purl.uniprot.org/uniprot/A0A060HU17 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/926571:NVIE_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A060HNK9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.|||Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.|||Homodecamer. http://togogenome.org/gene/926571:NVIE_RS13345 ^@ http://purl.uniprot.org/uniprot/A0A060HNM3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS06995 ^@ http://purl.uniprot.org/uniprot/A0A060HK55 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS13000 ^@ http://purl.uniprot.org/uniprot/A0A060HVC9 ^@ Similarity ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. http://togogenome.org/gene/926571:NVIE_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A060HJI9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.|||Binds 1 zinc ion.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/926571:NVIE_RS13510 ^@ http://purl.uniprot.org/uniprot/A0A060HNQ5 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/926571:NVIE_RS04110 ^@ http://purl.uniprot.org/uniprot/A0A060HPC3 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent DNA ligase family.|||DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. http://togogenome.org/gene/926571:NVIE_RS02370 ^@ http://purl.uniprot.org/uniprot/A0A060HN82 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/926571:NVIE_RS01340 ^@ http://purl.uniprot.org/uniprot/A0A060HMQ1 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/926571:NVIE_RS11270 ^@ http://purl.uniprot.org/uniprot/A0A060HU26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/926571:NVIE_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A060HR72 ^@ Similarity|||Subunit ^@ Belongs to the FBP aldolase/phosphatase family.|||Homooctamer; dimer of tetramers. http://togogenome.org/gene/926571:NVIE_RS13790 ^@ http://purl.uniprot.org/uniprot/A0A060HNV7 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/926571:NVIE_RS12990 ^@ http://purl.uniprot.org/uniprot/A0A060HPD2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/926571:NVIE_RS02440 ^@ http://purl.uniprot.org/uniprot/A0A060HH61 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS02315 ^@ http://purl.uniprot.org/uniprot/A0A060HN71 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS10305 ^@ http://purl.uniprot.org/uniprot/A0A060HTJ5 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/926571:NVIE_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A060HNS2 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/926571:NVIE_RS12080 ^@ http://purl.uniprot.org/uniprot/A0A060HUN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STT3 family.|||Membrane http://togogenome.org/gene/926571:NVIE_RS11565 ^@ http://purl.uniprot.org/uniprot/A0A060HJD6 ^@ Similarity ^@ Belongs to the phosphosulfolactate synthase family. http://togogenome.org/gene/926571:NVIE_RS02505 ^@ http://purl.uniprot.org/uniprot/A0A060HGI5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/926571:NVIE_RS05180 ^@ http://purl.uniprot.org/uniprot/A0A060HID7 ^@ Similarity ^@ Belongs to the UPF0166 family. http://togogenome.org/gene/926571:NVIE_RS10385 ^@ http://purl.uniprot.org/uniprot/A0A060HMS4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/926571:NVIE_RS11185 ^@ http://purl.uniprot.org/uniprot/A0A060HSY3 ^@ Function|||Similarity ^@ Belongs to the archaeal 6-HMPDK family.|||Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP). http://togogenome.org/gene/926571:NVIE_RS02840 ^@ http://purl.uniprot.org/uniprot/A0A060HHF2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type-I 3-dehydroquinase family.|||Homodimer.|||Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS07755 ^@ http://purl.uniprot.org/uniprot/A0A060HGY7 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/926571:NVIE_RS10525 ^@ http://purl.uniprot.org/uniprot/A0A060HMU3 ^@ Function|||Similarity ^@ Belongs to the archaeal-type GTP cyclohydrolase family.|||Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity. http://togogenome.org/gene/926571:NVIE_RS00805 ^@ http://purl.uniprot.org/uniprot/A0A060HFI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS13970 ^@ http://purl.uniprot.org/uniprot/A0A060HNY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS00130 ^@ http://purl.uniprot.org/uniprot/A0A060HBQ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase PH family. Rrp42 subfamily.|||Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. http://togogenome.org/gene/926571:NVIE_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A060HK93 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions. http://togogenome.org/gene/926571:NVIE_RS01285 ^@ http://purl.uniprot.org/uniprot/A0A060HLK9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family. LysK subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.|||Cytoplasm http://togogenome.org/gene/926571:NVIE_RS10990 ^@ http://purl.uniprot.org/uniprot/A0A060HN08 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. http://togogenome.org/gene/926571:NVIE_RS10055 ^@ http://purl.uniprot.org/uniprot/A0A060HIG2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS02085 ^@ http://purl.uniprot.org/uniprot/A0A060HM19 ^@ Similarity ^@ Belongs to the AdoMet synthase family. http://togogenome.org/gene/926571:NVIE_RS12050 ^@ http://purl.uniprot.org/uniprot/A0A060HTK6 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/926571:NVIE_RS13655 ^@ http://purl.uniprot.org/uniprot/A0A060HPR9 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/926571:NVIE_RS05525 ^@ http://purl.uniprot.org/uniprot/A0A060HQC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS10870 ^@ http://purl.uniprot.org/uniprot/A0A060HM29 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/926571:NVIE_RS08545 ^@ http://purl.uniprot.org/uniprot/A0A060HKL6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A060HK20 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS31 family.|||Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS04925 ^@ http://purl.uniprot.org/uniprot/A0A060HF00 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/926571:NVIE_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A060HN36 ^@ Function|||Similarity ^@ Belongs to the NOP10 family.|||Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. http://togogenome.org/gene/926571:NVIE_RS05200 ^@ http://purl.uniprot.org/uniprot/A0A060HIE3 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/926571:NVIE_RS04025 ^@ http://purl.uniprot.org/uniprot/A0A060HHK3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/926571:NVIE_RS04160 ^@ http://purl.uniprot.org/uniprot/A0A060HHN2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/926571:NVIE_RS01685 ^@ http://purl.uniprot.org/uniprot/A0A060HLS2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS08225 ^@ http://purl.uniprot.org/uniprot/A0A060HL75 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS12335 ^@ http://purl.uniprot.org/uniprot/A0A060HJZ2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/926571:NVIE_RS14010 ^@ http://purl.uniprot.org/uniprot/A0A060HVY7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL24 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14. http://togogenome.org/gene/926571:NVIE_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A060HDI8 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/926571:NVIE_RS11050 ^@ http://purl.uniprot.org/uniprot/A0A060HM63 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/926571:NVIE_RS01170 ^@ http://purl.uniprot.org/uniprot/A0A060HGH5 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/926571:NVIE_RS02380 ^@ http://purl.uniprot.org/uniprot/A0A060HD71 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS05605 ^@ http://purl.uniprot.org/uniprot/A0A060HQE4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS11690 ^@ http://purl.uniprot.org/uniprot/A0A060HJG2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic/archaeal RNase P protein component 4 family.|||Binds 1 zinc ion per subunit.|||Consists of a catalytic RNA component and at least 4-5 protein subunits.|||Cytoplasm|||Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. http://togogenome.org/gene/926571:NVIE_RS06735 ^@ http://purl.uniprot.org/uniprot/A0A060HR20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal adenylate kinase family.|||Cytoplasm http://togogenome.org/gene/926571:NVIE_RS02885 ^@ http://purl.uniprot.org/uniprot/A0A060HHG5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/926571:NVIE_RS04020 ^@ http://purl.uniprot.org/uniprot/A0A060HPB0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/926571:NVIE_RS01615 ^@ http://purl.uniprot.org/uniprot/A0A060HMU9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.|||Belongs to the histone-like Alba family.|||Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.|||Chromosome|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/926571:NVIE_RS10565 ^@ http://purl.uniprot.org/uniprot/A0A060HLX1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/926571:NVIE_RS10045 ^@ http://purl.uniprot.org/uniprot/A0A060HT84 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/926571:NVIE_RS11635 ^@ http://purl.uniprot.org/uniprot/A0A060HMI0 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eS27 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/926571:NVIE_RS05585 ^@ http://purl.uniprot.org/uniprot/A0A060HIP0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/926571:NVIE_RS03100 ^@ http://purl.uniprot.org/uniprot/A0A060HGZ6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/926571:NVIE_RS00365 ^@ http://purl.uniprot.org/uniprot/A0A060HKZ1 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/926571:NVIE_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A060HRK6 ^@ Caution|||Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS09090 ^@ http://purl.uniprot.org/uniprot/A0A060HSI0 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/926571:NVIE_RS09890 ^@ http://purl.uniprot.org/uniprot/A0A060HT42 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/926571:NVIE_RS08415 ^@ http://purl.uniprot.org/uniprot/A0A060HR54 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/926571:NVIE_RS12230 ^@ http://purl.uniprot.org/uniprot/A0A060HUS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/926571:NVIE_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A060HS79 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/926571:NVIE_RS06450 ^@ http://purl.uniprot.org/uniprot/A0A060HPU0 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/926571:NVIE_RS14020 ^@ http://purl.uniprot.org/uniprot/A0A060HL12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Cytoplasm|||Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.|||Part of the 50S ribosomal subunit. Probably part of the RNase P complex. http://togogenome.org/gene/926571:NVIE_RS03470 ^@ http://purl.uniprot.org/uniprot/A0A060HHB0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS10995 ^@ http://purl.uniprot.org/uniprot/A0A060HSU8 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. http://togogenome.org/gene/926571:NVIE_RS00110 ^@ http://purl.uniprot.org/uniprot/A0A060HFP5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the RNA polymerase complex. http://togogenome.org/gene/926571:NVIE_RS11415 ^@ http://purl.uniprot.org/uniprot/A0A060HN92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/926571:NVIE_RS08425 ^@ http://purl.uniprot.org/uniprot/A0A060HKJ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/926571:NVIE_RS05345 ^@ http://purl.uniprot.org/uniprot/A0A060HFD4 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/926571:NVIE_RS06480 ^@ http://purl.uniprot.org/uniprot/A0A060HQX6 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/926571:NVIE_RS05165 ^@ http://purl.uniprot.org/uniprot/A0A060HF77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/926571:NVIE_RS04130 ^@ http://purl.uniprot.org/uniprot/A0A060HPC7 ^@ Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/926571:NVIE_RS11995 ^@ http://purl.uniprot.org/uniprot/A0A060HNQ6 ^@ Similarity ^@ Belongs to the UPF0201 family. http://togogenome.org/gene/926571:NVIE_RS00510 ^@ http://purl.uniprot.org/uniprot/A0A060HFY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS03940 ^@ http://purl.uniprot.org/uniprot/A0A060HED0 ^@ Similarity ^@ Belongs to the isopentenyl phosphate kinase family. http://togogenome.org/gene/926571:NVIE_RS03200 ^@ http://purl.uniprot.org/uniprot/A0A060HHS0 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/926571:NVIE_RS08635 ^@ http://purl.uniprot.org/uniprot/A0A060HSA2 ^@ Subunit ^@ Homotrimer. http://togogenome.org/gene/926571:NVIE_RS07565 ^@ http://purl.uniprot.org/uniprot/A0A060HQH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/926571:NVIE_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A060HL43 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926571:NVIE_RS00115 ^@ http://purl.uniprot.org/uniprot/A0A060HKU3 ^@ Similarity ^@ Belongs to the SDO1/SBDS family. http://togogenome.org/gene/926571:NVIE_RS10520 ^@ http://purl.uniprot.org/uniprot/A0A060HIQ7 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/926571:NVIE_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A060HMY0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal Spt4 family.|||Heterodimer composed of Spt4 and Spt5.|||Stimulates transcription elongation. http://togogenome.org/gene/926571:NVIE_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A060HD38 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/926571:NVIE_RS14080 ^@ http://purl.uniprot.org/uniprot/A0A060HUX4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/926571:NVIE_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A060HE93 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926571:NVIE_RS11830 ^@ http://purl.uniprot.org/uniprot/A0A060HUF2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS01875 ^@ http://purl.uniprot.org/uniprot/A0A060HCW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS03685 ^@ http://purl.uniprot.org/uniprot/A0A060HP60 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/926571:NVIE_RS02825 ^@ http://purl.uniprot.org/uniprot/A0A060HNJ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/926571:NVIE_RS07440 ^@ http://purl.uniprot.org/uniprot/A0A060HQF6 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/926571:NVIE_RS02450 ^@ http://purl.uniprot.org/uniprot/A0A060HNA0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS4 family. http://togogenome.org/gene/926571:NVIE_RS04950 ^@ http://purl.uniprot.org/uniprot/A0A060HF07 ^@ Similarity ^@ Belongs to the CGI121/TPRKB family. http://togogenome.org/gene/926571:NVIE_RS03965 ^@ http://purl.uniprot.org/uniprot/A0A060HED3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the THI4 family.|||Homooctamer; tetramer of dimers.|||Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS10160 ^@ http://purl.uniprot.org/uniprot/A0A060HTC3 ^@ Function|||Similarity ^@ Belongs to the eIF-6 family.|||Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. http://togogenome.org/gene/926571:NVIE_RS05290 ^@ http://purl.uniprot.org/uniprot/A0A060HQ62 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL39 family. http://togogenome.org/gene/926571:NVIE_RS00340 ^@ http://purl.uniprot.org/uniprot/A0A060HKY7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL19 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS11245 ^@ http://purl.uniprot.org/uniprot/A0A060HU21 ^@ Similarity ^@ Belongs to the AAA ATPase family. CDC48 subfamily. http://togogenome.org/gene/926571:NVIE_RS11695 ^@ http://purl.uniprot.org/uniprot/A0A060HNG4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS19 family.|||May be involved in maturation of the 30S ribosomal subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS11645 ^@ http://purl.uniprot.org/uniprot/A0A060HNF1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/926571:NVIE_RS08025 ^@ http://purl.uniprot.org/uniprot/A0A060HKA9 ^@ Similarity ^@ Belongs to the RimK family. LysX subfamily. http://togogenome.org/gene/926571:NVIE_RS06590 ^@ http://purl.uniprot.org/uniprot/A0A060HJ97 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. http://togogenome.org/gene/926571:NVIE_RS10755 ^@ http://purl.uniprot.org/uniprot/A0A060HM07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal NMN adenylyltransferase family.|||Cytoplasm http://togogenome.org/gene/926571:NVIE_RS07135 ^@ http://purl.uniprot.org/uniprot/A0A060HK87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/926571:NVIE_RS06745 ^@ http://purl.uniprot.org/uniprot/A0A060HG71 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS13045 ^@ http://purl.uniprot.org/uniprot/A0A060HU99 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/926571:NVIE_RS03735 ^@ http://purl.uniprot.org/uniprot/A0A060HN46 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.|||Belongs to the histone-like Alba family.|||Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.|||Chromosome|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/926571:NVIE_RS00740 ^@ http://purl.uniprot.org/uniprot/A0A060HG41 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CofC family.|||Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.|||Homodimer. http://togogenome.org/gene/926571:NVIE_RS03380 ^@ http://purl.uniprot.org/uniprot/A0A060HI10 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/926571:NVIE_RS03805 ^@ http://purl.uniprot.org/uniprot/A0A060HI78 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/926571:NVIE_RS06845 ^@ http://purl.uniprot.org/uniprot/A0A060HQ21 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/926571:NVIE_RS12170 ^@ http://purl.uniprot.org/uniprot/A0A060HNV1 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/926571:NVIE_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A060HND7 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/926571:NVIE_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A060HMM6 ^@ Similarity ^@ Belongs to the UPF0284 family. http://togogenome.org/gene/926571:NVIE_RS06525 ^@ http://purl.uniprot.org/uniprot/A0A060HPV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NusA family.|||Cytoplasm|||Participates in transcription termination. http://togogenome.org/gene/926571:NVIE_RS06315 ^@ http://purl.uniprot.org/uniprot/A0A060HQU2 ^@ Function|||Similarity ^@ Belongs to the DPH1/DPH2 family.|||Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). http://togogenome.org/gene/926571:NVIE_RS08020 ^@ http://purl.uniprot.org/uniprot/A0A060HRX8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.|||Cytoplasm|||Involved in both the arginine and lysine biosynthetic pathways.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS08105 ^@ http://purl.uniprot.org/uniprot/A0A060HH77 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion. http://togogenome.org/gene/926571:NVIE_RS14075 ^@ http://purl.uniprot.org/uniprot/A0A060HQ20 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/926571:NVIE_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A060HFE5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/926571:NVIE_RS07460 ^@ http://purl.uniprot.org/uniprot/A0A060HGQ0 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/926571:NVIE_RS02475 ^@ http://purl.uniprot.org/uniprot/A0A060HNA6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/926571:NVIE_RS03370 ^@ http://purl.uniprot.org/uniprot/A0A060HH92 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/926571:NVIE_RS07110 ^@ http://purl.uniprot.org/uniprot/A0A060HGF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/926571:NVIE_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A060HQJ5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.|||Binds 1 zinc ion.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/926571:NVIE_RS14015 ^@ http://purl.uniprot.org/uniprot/A0A060HNZ5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family. http://togogenome.org/gene/926571:NVIE_RS04500 ^@ http://purl.uniprot.org/uniprot/A0A060HNK5 ^@ Function|||Similarity ^@ Belongs to the CDC6/cdc18 family.|||Involved in regulation of DNA replication. http://togogenome.org/gene/926571:NVIE_RS03350 ^@ http://purl.uniprot.org/uniprot/A0A060HP03 ^@ Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. http://togogenome.org/gene/926571:NVIE_RS01165 ^@ http://purl.uniprot.org/uniprot/A0A060HCI1 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/926571:NVIE_RS00065 ^@ http://purl.uniprot.org/uniprot/A0A060HKT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/926571:NVIE_RS00370 ^@ http://purl.uniprot.org/uniprot/A0A060HM47 ^@ Similarity ^@ Belongs to the ALAD family. http://togogenome.org/gene/926571:NVIE_RS05010 ^@ http://purl.uniprot.org/uniprot/A0A060HI90 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/926571:NVIE_RS08420 ^@ http://purl.uniprot.org/uniprot/A0A060HS61 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/926571:NVIE_RS12630 ^@ http://purl.uniprot.org/uniprot/A0A060HV62 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/926571:NVIE_RS11495 ^@ http://purl.uniprot.org/uniprot/A0A060HU74 ^@ Function|||Similarity ^@ Belongs to the GrpE family.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/926571:NVIE_RS06280 ^@ http://purl.uniprot.org/uniprot/A0A060HFZ3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/926571:NVIE_RS06730 ^@ http://purl.uniprot.org/uniprot/A0A060HPZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS11470 ^@ http://purl.uniprot.org/uniprot/A0A060HU69 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/926571:NVIE_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A060HIQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Archaeal flagellum|||Belongs to the archaeal flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella. http://togogenome.org/gene/926571:NVIE_RS11615 ^@ http://purl.uniprot.org/uniprot/A0A060HJE7 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/926571:NVIE_RS06065 ^@ http://purl.uniprot.org/uniprot/A0A060HJP6 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/926571:NVIE_RS01835 ^@ http://purl.uniprot.org/uniprot/A0A060HCV6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/926571:NVIE_RS03110 ^@ http://purl.uniprot.org/uniprot/A0A060HHP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/926571:NVIE_RS02140 ^@ http://purl.uniprot.org/uniprot/A0A060HM31 ^@ Similarity ^@ Belongs to the eIF-2-alpha family. http://togogenome.org/gene/926571:NVIE_RS13585 ^@ http://purl.uniprot.org/uniprot/A0A060HKS5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/926571:NVIE_RS06760 ^@ http://purl.uniprot.org/uniprot/A0A060HR24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/926571:NVIE_RS00350 ^@ http://purl.uniprot.org/uniprot/A0A060HF56 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DtdA deacylase family.|||Binds 2 Zn(2+) ions per subunit.|||D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.|||Monomer. http://togogenome.org/gene/926571:NVIE_RS08975 ^@ http://purl.uniprot.org/uniprot/A0A060HHM4 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/926571:NVIE_RS01650 ^@ http://purl.uniprot.org/uniprot/A0A060HCS0 ^@ Function|||Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family.|||Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. http://togogenome.org/gene/926571:NVIE_RS00760 ^@ http://purl.uniprot.org/uniprot/A0A060HC39 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SEC61-beta family.|||Cell membrane|||Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.|||Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.|||Membrane http://togogenome.org/gene/926571:NVIE_RS04180 ^@ http://purl.uniprot.org/uniprot/A0A060HPD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/926571:NVIE_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A060HI05 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/926571:NVIE_RS05920 ^@ http://purl.uniprot.org/uniprot/A0A060HPJ2 ^@ Similarity|||Subunit ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Homohexamer. http://togogenome.org/gene/926571:NVIE_RS09970 ^@ http://purl.uniprot.org/uniprot/A0A060HS67 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Arsenite methyltransferase family. http://togogenome.org/gene/926571:NVIE_RS06720 ^@ http://purl.uniprot.org/uniprot/A0A060HG65 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.|||Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/926571:NVIE_RS01125 ^@ http://purl.uniprot.org/uniprot/A0A060HLI2 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/926571:NVIE_RS07400 ^@ http://purl.uniprot.org/uniprot/A0A060HQE8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS02465 ^@ http://purl.uniprot.org/uniprot/A0A060HH64 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A060HQX8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. LysZ subfamily.|||Cytoplasm|||Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis). http://togogenome.org/gene/926571:NVIE_RS05760 ^@ http://purl.uniprot.org/uniprot/A0A060HIT2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS07835 ^@ http://purl.uniprot.org/uniprot/A0A060HKW9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19. http://togogenome.org/gene/926571:NVIE_RS13265 ^@ http://purl.uniprot.org/uniprot/A0A060HUE4 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/926571:NVIE_RS01145 ^@ http://purl.uniprot.org/uniprot/A0A060HGH1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the NnrE/AIBP family.|||Binds 1 potassium ion per subunit.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS00440 ^@ http://purl.uniprot.org/uniprot/A0A060HL06 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/926571:NVIE_RS11000 ^@ http://purl.uniprot.org/uniprot/A0A060HTX6 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/926571:NVIE_RS05950 ^@ http://purl.uniprot.org/uniprot/A0A060HQM4 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/926571:NVIE_RS02270 ^@ http://purl.uniprot.org/uniprot/A0A060HGD1 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/926571:NVIE_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A060HKU7 ^@ Similarity ^@ Belongs to the CTAG/PCC1 family. http://togogenome.org/gene/926571:NVIE_RS02125 ^@ http://purl.uniprot.org/uniprot/A0A060HGA2 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/926571:NVIE_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A060HIR2 ^@ Similarity ^@ Belongs to the complex I 20 kDa subunit family. http://togogenome.org/gene/926571:NVIE_RS12600 ^@ http://purl.uniprot.org/uniprot/A0A060HU30 ^@ Function ^@ Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA. http://togogenome.org/gene/926571:NVIE_RS14430 ^@ http://purl.uniprot.org/uniprot/A0A060HWA1 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/926571:NVIE_RS08325 ^@ http://purl.uniprot.org/uniprot/A0A060HS43 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS13680 ^@ http://purl.uniprot.org/uniprot/A0A060HPS6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS11425 ^@ http://purl.uniprot.org/uniprot/A0A060HU60 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/926571:NVIE_RS12660 ^@ http://purl.uniprot.org/uniprot/A0A060HN96 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/926571:NVIE_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A060HLL2 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/926571:NVIE_RS14025 ^@ http://purl.uniprot.org/uniprot/A0A060HQ08 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/926571:NVIE_RS13425 ^@ http://purl.uniprot.org/uniprot/A0A060HNN7 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/926571:NVIE_RS02835 ^@ http://purl.uniprot.org/uniprot/A0A060HDI1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS11665 ^@ http://purl.uniprot.org/uniprot/A0A060HJF8 ^@ Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Homodimer. http://togogenome.org/gene/926571:NVIE_RS07300 ^@ http://purl.uniprot.org/uniprot/A0A060HJQ2 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/926571:NVIE_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A060HIS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GHMP kinase family. Mevalonate kinase subfamily.|||Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926571:NVIE_RS11700 ^@ http://purl.uniprot.org/uniprot/A0A060HT99 ^@ Similarity ^@ Belongs to the PDCD5 family. http://togogenome.org/gene/926571:NVIE_RS10585 ^@ http://purl.uniprot.org/uniprot/A0A060HTP4 ^@ Function ^@ Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. http://togogenome.org/gene/926571:NVIE_RS00105 ^@ http://purl.uniprot.org/uniprot/A0A060HBP6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL18 family. http://togogenome.org/gene/926571:NVIE_RS14000 ^@ http://purl.uniprot.org/uniprot/A0A060HQ01 ^@ Caution|||Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS03670 ^@ http://purl.uniprot.org/uniprot/A0A060HE87 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/926571:NVIE_RS12940 ^@ http://purl.uniprot.org/uniprot/A0A060HNE5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS11630 ^@ http://purl.uniprot.org/uniprot/A0A060HUA7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL42 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS11410 ^@ http://purl.uniprot.org/uniprot/A0A060HJ98 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/926571:NVIE_RS05175 ^@ http://purl.uniprot.org/uniprot/A0A060HQ34 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/926571:NVIE_RS13730 ^@ http://purl.uniprot.org/uniprot/A0A060HPT9 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/926571:NVIE_RS02455 ^@ http://purl.uniprot.org/uniprot/A0A060HGH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||Located at the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS05620 ^@ http://purl.uniprot.org/uniprot/A0A060HJG6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS09485 ^@ http://purl.uniprot.org/uniprot/A0A060HM10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS00125 ^@ http://purl.uniprot.org/uniprot/A0A060HEZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase PH family. Rrp41 subfamily.|||Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.|||Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.|||Cytoplasm http://togogenome.org/gene/926571:NVIE_RS02675 ^@ http://purl.uniprot.org/uniprot/A0A060HHB2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/926571:NVIE_RS13315 ^@ http://purl.uniprot.org/uniprot/A0A060HVI3 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/926571:NVIE_RS14835 ^@ http://purl.uniprot.org/uniprot/A0A060HLH1 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/926571:NVIE_RS01535 ^@ http://purl.uniprot.org/uniprot/A0A060HLP7 ^@ Function|||Similarity ^@ Belongs to the archaeal riboflavin kinase family.|||Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN). http://togogenome.org/gene/926571:NVIE_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A060HNI0 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/926571:NVIE_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A060HE79 ^@ Function ^@ Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. http://togogenome.org/gene/926571:NVIE_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A060HIC1 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/926571:NVIE_RS10830 ^@ http://purl.uniprot.org/uniprot/A0A060HIV8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the archaeosine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS08435 ^@ http://purl.uniprot.org/uniprot/A0A060HLA6 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/926571:NVIE_RS13180 ^@ http://purl.uniprot.org/uniprot/A0A060HPG5 ^@ Similarity ^@ Belongs to the cytochrome c oxidase subunit 2 family. http://togogenome.org/gene/926571:NVIE_RS05710 ^@ http://purl.uniprot.org/uniprot/A0A060HIS3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/926571:NVIE_RS11060 ^@ http://purl.uniprot.org/uniprot/A0A060HN20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS01655 ^@ http://purl.uniprot.org/uniprot/A0A060HGR4 ^@ Similarity ^@ Belongs to the AAA ATPase family. CDC48 subfamily. http://togogenome.org/gene/926571:NVIE_RS07730 ^@ http://purl.uniprot.org/uniprot/A0A060HK04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS13095 ^@ http://purl.uniprot.org/uniprot/A0A060HVE8 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/926571:NVIE_RS07000 ^@ http://purl.uniprot.org/uniprot/A0A060HQ54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/926571:NVIE_RS03705 ^@ http://purl.uniprot.org/uniprot/A0A060HI62 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/926571:NVIE_RS12100 ^@ http://purl.uniprot.org/uniprot/A0A060HTL8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/926571:NVIE_RS03445 ^@ http://purl.uniprot.org/uniprot/A0A060HHA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS08170 ^@ http://purl.uniprot.org/uniprot/A0A060HH86 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the MRE11/RAD32 family.|||Binds 2 manganese ions per subunit.|||Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.|||Nuclease activity is regulated by Rad50.|||Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. http://togogenome.org/gene/926571:NVIE_RS01840 ^@ http://purl.uniprot.org/uniprot/A0A060HGU8 ^@ Function|||Similarity ^@ Belongs to the GTP-dependent DPCK family.|||Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). http://togogenome.org/gene/926571:NVIE_RS08615 ^@ http://purl.uniprot.org/uniprot/A0A060HKM8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/926571:NVIE_RS06515 ^@ http://purl.uniprot.org/uniprot/A0A060HG35 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS13370 ^@ http://purl.uniprot.org/uniprot/A0A060HNM8 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/926571:NVIE_RS14175 ^@ http://purl.uniprot.org/uniprot/A0A060HP22 ^@ Similarity ^@ Belongs to the Ahb/Nir family. http://togogenome.org/gene/926571:NVIE_RS12215 ^@ http://purl.uniprot.org/uniprot/A0A060HJW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/926571:NVIE_RS05310 ^@ http://purl.uniprot.org/uniprot/A0A060HQ69 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the methylthiotransferase family. CDKAL1 subfamily.|||Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/926571:NVIE_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A060HHA7 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RecA-like protein family.|||Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. http://togogenome.org/gene/926571:NVIE_RS07875 ^@ http://purl.uniprot.org/uniprot/A0A060HH16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/926571:NVIE_RS06770 ^@ http://purl.uniprot.org/uniprot/A0A060HG74 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/926571:NVIE_RS04570 ^@ http://purl.uniprot.org/uniprot/A0A060HNL9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS13630 ^@ http://purl.uniprot.org/uniprot/A0A060HPR4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS12065 ^@ http://purl.uniprot.org/uniprot/A0A060HJS1 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/926571:NVIE_RS00060 ^@ http://purl.uniprot.org/uniprot/A0A060HFN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/926571:NVIE_RS14455 ^@ http://purl.uniprot.org/uniprot/A0A060HP76 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A060HFR5 ^@ Similarity ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily. http://togogenome.org/gene/926571:NVIE_RS07735 ^@ http://purl.uniprot.org/uniprot/A0A060HGY1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS05625 ^@ http://purl.uniprot.org/uniprot/A0A060HPD0 ^@ Similarity ^@ Belongs to the complex I 49 kDa subunit family. http://togogenome.org/gene/926571:NVIE_RS04830 ^@ http://purl.uniprot.org/uniprot/A0A060HIR5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Archaeal flagellum|||Belongs to the archaeal flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella. http://togogenome.org/gene/926571:NVIE_RS02815 ^@ http://purl.uniprot.org/uniprot/A0A060HHE7 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926571:NVIE_RS00025 ^@ http://purl.uniprot.org/uniprot/A0A060HEX9 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/926571:NVIE_RS07275 ^@ http://purl.uniprot.org/uniprot/A0A060HJP8 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/926571:NVIE_RS11280 ^@ http://purl.uniprot.org/uniprot/A0A060HJ64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/926571:NVIE_RS10665 ^@ http://purl.uniprot.org/uniprot/A0A060HLY9 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/926571:NVIE_RS02645 ^@ http://purl.uniprot.org/uniprot/A0A060HDD1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A060HM48 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS10375 ^@ http://purl.uniprot.org/uniprot/A0A060HLU1 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/926571:NVIE_RS04835 ^@ http://purl.uniprot.org/uniprot/A0A060HNS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Archaeal flagellum|||Belongs to the archaeal flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella. http://togogenome.org/gene/926571:NVIE_RS15995 ^@ http://purl.uniprot.org/uniprot/A0A060HW94 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/926571:NVIE_RS01570 ^@ http://purl.uniprot.org/uniprot/A0A060HMU1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/926571:NVIE_RS08875 ^@ http://purl.uniprot.org/uniprot/A0A060HKS4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAC-alpha family.|||Contacts the emerging nascent chain on the ribosome.|||Homodimer. Interacts with the ribosome. Binds ribosomal RNA. http://togogenome.org/gene/926571:NVIE_RS02550 ^@ http://purl.uniprot.org/uniprot/A0A060HNC4 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/926571:NVIE_RS12020 ^@ http://purl.uniprot.org/uniprot/A0A060HNR3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/926571:NVIE_RS13600 ^@ http://purl.uniprot.org/uniprot/A0A060HVP2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/926571:NVIE_RS13535 ^@ http://purl.uniprot.org/uniprot/A0A060HNR0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the TOP6B family.|||Homodimer. Heterotetramer of two Top6A and two Top6B chains.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Relaxes both positive and negative superturns and exhibits a strong decatenase activity. http://togogenome.org/gene/926571:NVIE_RS01290 ^@ http://purl.uniprot.org/uniprot/A0A060HMP5 ^@ Similarity ^@ Belongs to the RimK family. LysX subfamily. http://togogenome.org/gene/926571:NVIE_RS01250 ^@ http://purl.uniprot.org/uniprot/A0A060HCJ8 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/926571:NVIE_RS08295 ^@ http://purl.uniprot.org/uniprot/A0A060HL88 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/926571:NVIE_RS02460 ^@ http://purl.uniprot.org/uniprot/A0A060HD91 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges. http://togogenome.org/gene/926571:NVIE_RS03910 ^@ http://purl.uniprot.org/uniprot/A0A060HP91 ^@ Similarity ^@ Belongs to the AAA ATPase family. CDC48 subfamily. http://togogenome.org/gene/926571:NVIE_RS11510 ^@ http://purl.uniprot.org/uniprot/A0A060HNB5 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/926571:NVIE_RS01720 ^@ http://purl.uniprot.org/uniprot/A0A060HG26 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/926571:NVIE_RS00335 ^@ http://purl.uniprot.org/uniprot/A0A060HFU5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/926571:NVIE_RS03385 ^@ http://purl.uniprot.org/uniprot/A0A060HMZ5 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/926571:NVIE_RS06800 ^@ http://purl.uniprot.org/uniprot/A0A060HQ12 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/926571:NVIE_RS08990 ^@ http://purl.uniprot.org/uniprot/A0A060HKU4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/926571:NVIE_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A060HNL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic-type primase small subunit family.|||Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.|||Heterodimer of a small subunit (PriS) and a large subunit (PriL).|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/926571:NVIE_RS06470 ^@ http://purl.uniprot.org/uniprot/A0A060HJX0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. Hel308 subfamily.|||DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.|||Monomer. http://togogenome.org/gene/926571:NVIE_RS09905 ^@ http://purl.uniprot.org/uniprot/A0A060HS44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.|||Belongs to the TiaS family.|||Cytoplasm http://togogenome.org/gene/926571:NVIE_RS13985 ^@ http://purl.uniprot.org/uniprot/A0A060HVY1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/926571:NVIE_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A060HMF5 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/926571:NVIE_RS10430 ^@ http://purl.uniprot.org/uniprot/A0A060HMS6 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/926571:NVIE_RS10515 ^@ http://purl.uniprot.org/uniprot/A0A060HLW2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/926571:NVIE_RS12345 ^@ http://purl.uniprot.org/uniprot/A0A060HTT4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/926571:NVIE_RS11500 ^@ http://purl.uniprot.org/uniprot/A0A060HMF2 ^@ Function|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family. http://togogenome.org/gene/926571:NVIE_RS11255 ^@ http://purl.uniprot.org/uniprot/A0A060HJ58 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/926571:NVIE_RS13085 ^@ http://purl.uniprot.org/uniprot/A0A060HPE7 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/926571:NVIE_RS11735 ^@ http://purl.uniprot.org/uniprot/A0A060HUD1 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/926571:NVIE_RS00675 ^@ http://purl.uniprot.org/uniprot/A0A060HG29 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926571:NVIE_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A060HM32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS03630 ^@ http://purl.uniprot.org/uniprot/A0A060HI51 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/926571:NVIE_RS08930 ^@ http://purl.uniprot.org/uniprot/A0A060HHL3 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/926571:NVIE_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A060HH48 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/926571:NVIE_RS14005 ^@ http://purl.uniprot.org/uniprot/A0A060HUV7 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/926571:NVIE_RS06545 ^@ http://purl.uniprot.org/uniprot/A0A060HJY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/926571:NVIE_RS12320 ^@ http://purl.uniprot.org/uniprot/A0A060HTS9 ^@ Function ^@ CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/926571:NVIE_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A060HGK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/926571:NVIE_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A060HQ75 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/926571:NVIE_RS02490 ^@ http://purl.uniprot.org/uniprot/A0A060HH67 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/926571:NVIE_RS10195 ^@ http://purl.uniprot.org/uniprot/A0A060HIK2 ^@ Similarity|||Subunit ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.|||Heterooligomer of catalytic and regulatory chains. http://togogenome.org/gene/926571:NVIE_RS14400 ^@ http://purl.uniprot.org/uniprot/A0A060HV45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prefoldin alpha subunit family.|||Belongs to the prefoldin subunit alpha family.|||Cytoplasm|||Heterohexamer of two alpha and four beta subunits.|||Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. http://togogenome.org/gene/926571:NVIE_RS09085 ^@ http://purl.uniprot.org/uniprot/A0A060HRG9 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/926571:NVIE_RS01950 ^@ http://purl.uniprot.org/uniprot/A0A060HLZ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/926571:NVIE_RS05295 ^@ http://purl.uniprot.org/uniprot/A0A060HIG5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL31 family. http://togogenome.org/gene/926571:NVIE_RS13965 ^@ http://purl.uniprot.org/uniprot/A0A060HVX6 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/926571:NVIE_RS11650 ^@ http://purl.uniprot.org/uniprot/A0A060HT85 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/926571:NVIE_RS06485 ^@ http://purl.uniprot.org/uniprot/A0A060HJ77 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/926571:NVIE_RS07100 ^@ http://purl.uniprot.org/uniprot/A0A060HR88 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/926571:NVIE_RS10670 ^@ http://purl.uniprot.org/uniprot/A0A060HIS5 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/926571:NVIE_RS11265 ^@ http://purl.uniprot.org/uniprot/A0A060HT02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/926571:NVIE_RS00200 ^@ http://purl.uniprot.org/uniprot/A0A060HF15 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/926571:NVIE_RS07960 ^@ http://purl.uniprot.org/uniprot/A0A060HL07 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL15 family. http://togogenome.org/gene/926571:NVIE_RS04125 ^@ http://purl.uniprot.org/uniprot/A0A060HNC6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/926571:NVIE_RS05775 ^@ http://purl.uniprot.org/uniprot/A0A060HPG6 ^@ Similarity ^@ Belongs to the AAA ATPase family. CDC48 subfamily. http://togogenome.org/gene/926571:NVIE_RS07290 ^@ http://purl.uniprot.org/uniprot/A0A060HQC5 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions. http://togogenome.org/gene/926571:NVIE_RS08370 ^@ http://purl.uniprot.org/uniprot/A0A060HR46 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.|||Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Homohexamer. Dimer of a homotrimer.|||Purine nucleoside phosphorylase involved in purine salvage. http://togogenome.org/gene/926571:NVIE_RS02615 ^@ http://purl.uniprot.org/uniprot/A0A060HNE3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm|||Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.|||Heterodimer of two subunits, one of which binds GTP. http://togogenome.org/gene/926571:NVIE_RS04205 ^@ http://purl.uniprot.org/uniprot/A0A060HHP4 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/926571:NVIE_RS06615 ^@ http://purl.uniprot.org/uniprot/A0A060HJA2 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/926571:NVIE_RS04185 ^@ http://purl.uniprot.org/uniprot/A0A060HHN8 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/926571:NVIE_RS06820 ^@ http://purl.uniprot.org/uniprot/A0A060HK23 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/926571:NVIE_RS00995 ^@ http://purl.uniprot.org/uniprot/A0A060HFM6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/926571:NVIE_RS03095 ^@ http://purl.uniprot.org/uniprot/A0A060HNR8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/926571:NVIE_RS00100 ^@ http://purl.uniprot.org/uniprot/A0A060HEZ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/926571:NVIE_RS10825 ^@ http://purl.uniprot.org/uniprot/A0A060HM20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/926571:NVIE_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A060HIF8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL37 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA. http://togogenome.org/gene/926571:NVIE_RS10945 ^@ http://purl.uniprot.org/uniprot/A0A060HMZ9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/926571:NVIE_RS05890 ^@ http://purl.uniprot.org/uniprot/A0A060HPI9 ^@ Similarity ^@ Belongs to the UPF0166 family. http://togogenome.org/gene/926571:NVIE_RS13530 ^@ http://purl.uniprot.org/uniprot/A0A060HVM6 ^@ Similarity ^@ Belongs to the TOP6A family. http://togogenome.org/gene/926571:NVIE_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A060HEH8 ^@ Similarity ^@ Belongs to the DeoC/FbaB aldolase family. http://togogenome.org/gene/926571:NVIE_RS03220 ^@ http://purl.uniprot.org/uniprot/A0A060HMR4 ^@ Similarity ^@ Belongs to the UPF0147 family. http://togogenome.org/gene/926571:NVIE_RS07860 ^@ http://purl.uniprot.org/uniprot/A0A060HKX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/926571:NVIE_RS01380 ^@ http://purl.uniprot.org/uniprot/A0A060HGL2 ^@ Similarity ^@ Belongs to the archease family.