http://togogenome.org/gene/929813:AWC35_RS01595 ^@ http://purl.uniprot.org/uniprot/A0A250AWE5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/929813:AWC35_RS08425 ^@ http://purl.uniprot.org/uniprot/A0A250AZE1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/929813:AWC35_RS20785 ^@ http://purl.uniprot.org/uniprot/A0A250B5G9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/929813:AWC35_RS13490 ^@ http://purl.uniprot.org/uniprot/A0A250B1R8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/929813:AWC35_RS15260 ^@ http://purl.uniprot.org/uniprot/A0A250B2X1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/929813:AWC35_RS01685 ^@ http://purl.uniprot.org/uniprot/A0A250AWS3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929813:AWC35_RS12560 ^@ http://purl.uniprot.org/uniprot/A0A250B1B2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/929813:AWC35_RS06550 ^@ http://purl.uniprot.org/uniprot/A0A250AYS6 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/929813:AWC35_RS14350 ^@ http://purl.uniprot.org/uniprot/A0A250B2E0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/929813:AWC35_RS15660 ^@ http://purl.uniprot.org/uniprot/A0A250B3P9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/929813:AWC35_RS15255 ^@ http://purl.uniprot.org/uniprot/A0A250B2N8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/929813:AWC35_RS10440 ^@ http://purl.uniprot.org/uniprot/A0A250B0H8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NusG family.|||Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.|||Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination. http://togogenome.org/gene/929813:AWC35_RS13595 ^@ http://purl.uniprot.org/uniprot/A0A250B232 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/929813:AWC35_RS13545 ^@ http://purl.uniprot.org/uniprot/A0A250B220 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/929813:AWC35_RS13640 ^@ http://purl.uniprot.org/uniprot/A0A250B2A1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/929813:AWC35_RS06000 ^@ http://purl.uniprot.org/uniprot/A0A250AYA4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/929813:AWC35_RS13535 ^@ http://purl.uniprot.org/uniprot/A0A250B2M3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/929813:AWC35_RS19410 ^@ http://purl.uniprot.org/uniprot/A0A250B559 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/929813:AWC35_RS14280 ^@ http://purl.uniprot.org/uniprot/A0A250B2G3 ^@ Function|||Similarity|||Subunit ^@ Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.|||Belongs to the transcriptional regulatory Fis family.|||Homodimer. http://togogenome.org/gene/929813:AWC35_RS09730 ^@ http://purl.uniprot.org/uniprot/A0A250B0D1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/929813:AWC35_RS01625 ^@ http://purl.uniprot.org/uniprot/A0A250AWR7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929813:AWC35_RS20660 ^@ http://purl.uniprot.org/uniprot/A0A250B5P6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/929813:AWC35_RS13575 ^@ http://purl.uniprot.org/uniprot/A0A250B1U6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/929813:AWC35_RS20350 ^@ http://purl.uniprot.org/uniprot/A0A250B5I5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/929813:AWC35_RS23030 ^@ http://purl.uniprot.org/uniprot/A0A250B6X5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/929813:AWC35_RS11830 ^@ http://purl.uniprot.org/uniprot/A0A250B1G2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/929813:AWC35_RS13655 ^@ http://purl.uniprot.org/uniprot/A0A250B238 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/929813:AWC35_RS06485 ^@ http://purl.uniprot.org/uniprot/A0A250AYB3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/929813:AWC35_RS09655 ^@ http://purl.uniprot.org/uniprot/A0A250B0P1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/929813:AWC35_RS13590 ^@ http://purl.uniprot.org/uniprot/A0A250B1T9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/929813:AWC35_RS12320 ^@ http://purl.uniprot.org/uniprot/A0A250B1M4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/929813:AWC35_RS23585 ^@ http://purl.uniprot.org/uniprot/A0A250B752 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/929813:AWC35_RS21225 ^@ http://purl.uniprot.org/uniprot/A0A250B5N0 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/929813:AWC35_RS23810 ^@ http://purl.uniprot.org/uniprot/A0A250B6X2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.|||Belongs to the Lpp family.|||Cell outer membrane|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||cell wall http://togogenome.org/gene/929813:AWC35_RS13565 ^@ http://purl.uniprot.org/uniprot/A0A250B1U5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/929813:AWC35_RS13610 ^@ http://purl.uniprot.org/uniprot/A0A250B246 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/929813:AWC35_RS12260 ^@ http://purl.uniprot.org/uniprot/A0A250B1D7 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/929813:AWC35_RS20765 ^@ http://purl.uniprot.org/uniprot/A0A250B8J2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/929813:AWC35_RS12565 ^@ http://purl.uniprot.org/uniprot/A0A250B1R4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MetJ family.|||Cytoplasm|||Does not bind DNA by a helix-turn-helix motif.|||Homodimer.|||This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. http://togogenome.org/gene/929813:AWC35_RS13520 ^@ http://purl.uniprot.org/uniprot/A0A250B1Y1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/929813:AWC35_RS08350 ^@ http://purl.uniprot.org/uniprot/A0A250AZD1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/929813:AWC35_RS13555 ^@ http://purl.uniprot.org/uniprot/A0A250B2B2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/929813:AWC35_RS10435 ^@ http://purl.uniprot.org/uniprot/A0A250B0A4 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/929813:AWC35_RS13550 ^@ http://purl.uniprot.org/uniprot/A0A250B285 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/929813:AWC35_RS13650 ^@ http://purl.uniprot.org/uniprot/A0A250B1U9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.