http://togogenome.org/gene/931089:CDES_RS10925 ^@ http://purl.uniprot.org/uniprot/A0A0M5IJB5 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/931089:CDES_RS02365 ^@ http://purl.uniprot.org/uniprot/A0A0M4CCI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS13865 ^@ http://purl.uniprot.org/uniprot/A0A0M3QAB6 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/931089:CDES_RS07845 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXL5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS03975 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWR5 ^@ Similarity ^@ Belongs to the transglycosylase family. Rpf subfamily. http://togogenome.org/gene/931089:CDES_RS13075 ^@ http://purl.uniprot.org/uniprot/A0A0M4D0A3 ^@ Similarity ^@ Belongs to the UPF0371 family. http://togogenome.org/gene/931089:CDES_RS02645 ^@ http://purl.uniprot.org/uniprot/A0A0M4CCK7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/931089:CDES_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIY6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/931089:CDES_RS12300 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNN5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/931089:CDES_RS05595 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXE8 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/931089:CDES_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNM4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/931089:CDES_RS12535 ^@ http://purl.uniprot.org/uniprot/A0A0M5IPR0 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS09645 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS13245 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA91 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/931089:CDES_RS09325 ^@ http://purl.uniprot.org/uniprot/A0A0M5IJ69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS11770 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA68 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/931089:CDES_RS11335 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA16 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/931089:CDES_RS06510 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLP1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS08245 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIT1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS03470 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q977 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS13310 ^@ http://purl.uniprot.org/uniprot/A0A0M4CS57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS11855 ^@ http://purl.uniprot.org/uniprot/A0A0M4CK16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS10690 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS04750 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFA8 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/931089:CDES_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI05 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.|||Homodimer.|||Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. http://togogenome.org/gene/931089:CDES_RS05325 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPD3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS06870 ^@ http://purl.uniprot.org/uniprot/A0A0M4CDW8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS00700 ^@ http://purl.uniprot.org/uniprot/A0A0M5II38 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS12825 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI74 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/931089:CDES_RS10220 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH89 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS04355 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHJ5 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/931089:CDES_RS08420 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/931089:CDES_RS02680 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/931089:CDES_RS10395 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYK7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/931089:CDES_RS05160 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS09630 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKC3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/931089:CDES_RS07695 ^@ http://purl.uniprot.org/uniprot/A0A0M4CY82 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS01285 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJV0 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/931089:CDES_RS07735 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGD2 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/931089:CDES_RS08630 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMD7 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/931089:CDES_RS06515 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9K8 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/931089:CDES_RS09865 ^@ http://purl.uniprot.org/uniprot/A0A0M5IUJ1 ^@ Similarity ^@ Belongs to the ribonuclease N1/T1 family. http://togogenome.org/gene/931089:CDES_RS03925 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q995 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/931089:CDES_RS13205 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS12165 ^@ http://purl.uniprot.org/uniprot/A0A0M4CRR4 ^@ Function ^@ Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors. http://togogenome.org/gene/931089:CDES_RS07955 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIQ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS09440 ^@ http://purl.uniprot.org/uniprot/A0A0M5IRC5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/931089:CDES_RS11990 ^@ http://purl.uniprot.org/uniprot/A0A0M4CK32 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/931089:CDES_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A0M5IJ66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS09555 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Cell membrane|||Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis. http://togogenome.org/gene/931089:CDES_RS03890 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWQ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/931089:CDES_RS11250 ^@ http://purl.uniprot.org/uniprot/A0A0M4CF67 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/931089:CDES_RS05750 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIZ3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/931089:CDES_RS08045 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJS2 ^@ Similarity ^@ Belongs to the DyP-type peroxidase family. http://togogenome.org/gene/931089:CDES_RS05060 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWH7 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/931089:CDES_RS07685 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQ87 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS13375 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFU7 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/931089:CDES_RS13700 ^@ http://purl.uniprot.org/uniprot/A0A0M3QAE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS03865 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEZ2 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/931089:CDES_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A0M5IJ59 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A0M5IQK2 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/931089:CDES_RS03785 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVZ3 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/931089:CDES_RS03875 ^@ http://purl.uniprot.org/uniprot/A0A0M4CCZ8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/931089:CDES_RS05950 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPK8 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/931089:CDES_RS13305 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/931089:CDES_RS11660 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJZ5 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/931089:CDES_RS09965 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/931089:CDES_RS13145 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKH6 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/931089:CDES_RS07700 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/931089:CDES_RS06505 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI97 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/931089:CDES_RS06380 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI84 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/931089:CDES_RS11050 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA06 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/931089:CDES_RS08480 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEC3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.|||Membrane http://togogenome.org/gene/931089:CDES_RS12035 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/931089:CDES_RS10145 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYH3 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/931089:CDES_RS06180 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVY3 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/931089:CDES_RS08935 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9T8 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/931089:CDES_RS03455 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWJ9 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/931089:CDES_RS11290 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA14 ^@ Caution|||Similarity ^@ Belongs to the nitrobindin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Lacks the conserved His residue that binds heme iron in the nitrobindin family. http://togogenome.org/gene/931089:CDES_RS07915 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXM4 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/931089:CDES_RS12525 ^@ http://purl.uniprot.org/uniprot/A0A0M4CRW3 ^@ Similarity ^@ Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family. http://togogenome.org/gene/931089:CDES_RS12695 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS06950 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXY1 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic ubiquitin-like protein family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.|||Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.|||The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome. http://togogenome.org/gene/931089:CDES_RS09365 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/931089:CDES_RS02235 ^@ http://purl.uniprot.org/uniprot/A0A0M4CCG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS10555 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Y8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/931089:CDES_RS04555 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9C2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS07740 ^@ http://purl.uniprot.org/uniprot/A0A0M4CE52 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/931089:CDES_RS11455 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZM6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the diaminopimelate dehydrogenase family.|||Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.|||Homodimer. http://togogenome.org/gene/931089:CDES_RS08975 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/931089:CDES_RS12440 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZD3 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/931089:CDES_RS11860 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS11905 ^@ http://purl.uniprot.org/uniprot/A0A0M4CRN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS02965 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q955 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family. http://togogenome.org/gene/931089:CDES_RS02675 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKB6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/931089:CDES_RS03160 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q965 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. DnaE2 subfamily.|||Cytoplasm|||DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. http://togogenome.org/gene/931089:CDES_RS06620 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPX0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/931089:CDES_RS10775 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJN8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/931089:CDES_RS09470 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEM6 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/931089:CDES_RS02280 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVD3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III. http://togogenome.org/gene/931089:CDES_RS10075 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Membrane http://togogenome.org/gene/931089:CDES_RS10265 ^@ http://purl.uniprot.org/uniprot/A0A0M5IJ98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQD3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/931089:CDES_RS00155 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrgA family.|||Cell membrane|||Involved in cell division. http://togogenome.org/gene/931089:CDES_RS10695 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJN0 ^@ Similarity ^@ Belongs to the truncated hemoglobin family. Group II subfamily. http://togogenome.org/gene/931089:CDES_RS11180 ^@ http://purl.uniprot.org/uniprot/A0A0M4CRC8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/931089:CDES_RS08640 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXW8 ^@ Similarity ^@ Belongs to the MQO family. http://togogenome.org/gene/931089:CDES_RS10645 ^@ http://purl.uniprot.org/uniprot/A0A0M5IMB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS04035 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q999 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/931089:CDES_RS01190 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVL3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/931089:CDES_RS10495 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZA4 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/931089:CDES_RS01600 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/931089:CDES_RS05360 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/931089:CDES_RS09110 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9M8 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/931089:CDES_RS08955 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9W3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/931089:CDES_RS11910 ^@ http://purl.uniprot.org/uniprot/A0A0M5IPP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Membrane http://togogenome.org/gene/931089:CDES_RS05960 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9G7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS09060 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9W7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/931089:CDES_RS02530 ^@ http://purl.uniprot.org/uniprot/A0A0M5ITQ6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/931089:CDES_RS02795 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKD0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/931089:CDES_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Z4 ^@ Similarity ^@ Belongs to the adenylyl cyclase class-3 family. http://togogenome.org/gene/931089:CDES_RS00345 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVB2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS12700 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI61 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/931089:CDES_RS00180 ^@ http://purl.uniprot.org/uniprot/A0A0M4CUJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A0M4CC06 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/931089:CDES_RS12950 ^@ http://purl.uniprot.org/uniprot/A0A0M4D085 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/931089:CDES_RS06520 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS04820 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFB8 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/931089:CDES_RS11665 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNG0 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/931089:CDES_RS13010 ^@ http://purl.uniprot.org/uniprot/A0A0M4D094 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/931089:CDES_RS11545 ^@ http://purl.uniprot.org/uniprot/A0A0M5IJ11 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/931089:CDES_RS04310 ^@ http://purl.uniprot.org/uniprot/A0A0M4CW70 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 39 family.|||Cell membrane|||Membrane|||Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. http://togogenome.org/gene/931089:CDES_RS07045 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJF0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/931089:CDES_RS01770 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVU7 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/931089:CDES_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A0M4CD38 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/931089:CDES_RS08030 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9R9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.|||Cell membrane|||Contains a di-nuclear catalytic Mg(2+) center.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/931089:CDES_RS01425 ^@ http://purl.uniprot.org/uniprot/A0A0M4CUZ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS13830 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8X1 ^@ Similarity ^@ Belongs to the SIS family. PHI subfamily. http://togogenome.org/gene/931089:CDES_RS04480 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHK9 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS08345 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS02815 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q948 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/931089:CDES_RS13620 ^@ http://purl.uniprot.org/uniprot/A0A0M5IM66 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/931089:CDES_RS08500 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIV8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS09150 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEJ7 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/931089:CDES_RS10370 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZ88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/931089:CDES_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVE0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS04470 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9B8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/931089:CDES_RS05265 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPC5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS09320 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9X7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/931089:CDES_RS09375 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJ63 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/931089:CDES_RS08695 ^@ http://purl.uniprot.org/uniprot/A0A0M5IJ51 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/931089:CDES_RS02630 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHZ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/931089:CDES_RS11840 ^@ http://purl.uniprot.org/uniprot/A0A0M4CRM7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS00375 ^@ http://purl.uniprot.org/uniprot/A0A0M5II28 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class II subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/931089:CDES_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHI7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS03020 ^@ http://purl.uniprot.org/uniprot/A0A0M5IFU1 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/931089:CDES_RS11495 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA22 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/931089:CDES_RS11800 ^@ http://purl.uniprot.org/uniprot/A0A0M5IGI9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS12470 ^@ http://purl.uniprot.org/uniprot/A0A0M5IUS0 ^@ Similarity ^@ Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family. http://togogenome.org/gene/931089:CDES_RS05310 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9E6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/931089:CDES_RS03670 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q985 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/931089:CDES_RS05630 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHX9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/931089:CDES_RS05210 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9E2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI55 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-73 and Arg-76) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. http://togogenome.org/gene/931089:CDES_RS07660 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXJ2 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/931089:CDES_RS03960 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNV0 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/931089:CDES_RS08730 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQJ6 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/931089:CDES_RS03745 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q990 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/931089:CDES_RS02700 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNA8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/931089:CDES_RS07095 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIG6 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/931089:CDES_RS11120 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS10165 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEV4 ^@ Similarity ^@ Belongs to the glucose-6-phosphate 1-epimerase family. http://togogenome.org/gene/931089:CDES_RS12845 ^@ http://purl.uniprot.org/uniprot/A0A0M4D077 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS10290 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEW6 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/931089:CDES_RS05650 ^@ http://purl.uniprot.org/uniprot/A0A0M5ITZ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/931089:CDES_RS01065 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.|||Belongs to the emb family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS03685 ^@ http://purl.uniprot.org/uniprot/A0A0M4CCX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LpqB lipoprotein family.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS02075 ^@ http://purl.uniprot.org/uniprot/A0A0M4CW02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/931089:CDES_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A0M4CCF2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyltransferase group 1 family. MshA subfamily.|||Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.|||Homodimer. http://togogenome.org/gene/931089:CDES_RS04450 ^@ http://purl.uniprot.org/uniprot/A0A0M4CF66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS12550 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNS2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/931089:CDES_RS10175 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA11 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/931089:CDES_RS04030 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWS4 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/931089:CDES_RS10400 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKM4 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/931089:CDES_RS07725 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Q7 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/931089:CDES_RS11345 ^@ http://purl.uniprot.org/uniprot/A0A0M5IMC7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/931089:CDES_RS10410 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHB3 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/931089:CDES_RS02745 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI10 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/931089:CDES_RS06445 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9I5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS01310 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Y2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/931089:CDES_RS07575 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Q1 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/931089:CDES_RS03000 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEN7 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/931089:CDES_RS01350 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJV8 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/931089:CDES_RS07990 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGG6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/931089:CDES_RS09395 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9U9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8W8 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/931089:CDES_RS05640 ^@ http://purl.uniprot.org/uniprot/A0A0M4CDJ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/931089:CDES_RS02660 ^@ http://purl.uniprot.org/uniprot/A0A0M4CW83 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/931089:CDES_RS02805 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVK1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/931089:CDES_RS07950 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYB4 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/931089:CDES_RS04150 ^@ http://purl.uniprot.org/uniprot/A0A0M4CD24 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS02785 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q952 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/931089:CDES_RS06480 ^@ http://purl.uniprot.org/uniprot/A0A0M4CDT1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/931089:CDES_RS11005 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKU9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/931089:CDES_RS07535 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXH8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVQ3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS06930 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9M3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/931089:CDES_RS06475 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFY0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/931089:CDES_RS11340 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNB1 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/931089:CDES_RS05175 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIU1 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/931089:CDES_RS03145 ^@ http://purl.uniprot.org/uniprot/A0A0M5ITS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS03270 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWH2 ^@ Cofactor|||Similarity ^@ Belongs to the monomeric-type IDH family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/931089:CDES_RS11270 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZK2 ^@ Similarity ^@ Belongs to the PstS family. http://togogenome.org/gene/931089:CDES_RS09435 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMN9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/931089:CDES_RS11375 ^@ http://purl.uniprot.org/uniprot/A0A0M4CRH2 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/931089:CDES_RS11755 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHT5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/931089:CDES_RS08700 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9S3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/931089:CDES_RS05300 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane http://togogenome.org/gene/931089:CDES_RS11075 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA44 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/931089:CDES_RS12810 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/931089:CDES_RS11825 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHU4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/931089:CDES_RS04325 ^@ http://purl.uniprot.org/uniprot/A0A0M4CF51 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Monomer. http://togogenome.org/gene/931089:CDES_RS10130 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS12415 ^@ http://purl.uniprot.org/uniprot/A0A0M4D007 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. http://togogenome.org/gene/931089:CDES_RS13370 ^@ http://purl.uniprot.org/uniprot/A0A0M3QAD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS02105 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHT6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS01265 ^@ http://purl.uniprot.org/uniprot/A0A0M5ITL6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIN4 ^@ Similarity ^@ Belongs to the non-flavoprotein flavin reductase family. http://togogenome.org/gene/931089:CDES_RS10465 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKN2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/931089:CDES_RS12155 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHY3 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/931089:CDES_RS01050 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Z1 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/931089:CDES_RS09890 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMU4 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/931089:CDES_RS02385 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGY2 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/931089:CDES_RS01420 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS10605 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHD7 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/931089:CDES_RS06785 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIZ1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/931089:CDES_RS00430 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreF family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/931089:CDES_RS03695 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q988 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/931089:CDES_RS01275 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Z9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/931089:CDES_RS02980 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKF9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/931089:CDES_RS03230 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q968 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/931089:CDES_RS04945 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFD3 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/931089:CDES_RS07635 ^@ http://purl.uniprot.org/uniprot/A0A0M4CY74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/931089:CDES_RS09220 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEK3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/931089:CDES_RS06545 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9I9 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/931089:CDES_RS10700 ^@ http://purl.uniprot.org/uniprot/A0A0M4CN54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS06335 ^@ http://purl.uniprot.org/uniprot/A0A0M4CX13 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/931089:CDES_RS09410 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS10035 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKH3 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/931089:CDES_RS09510 ^@ http://purl.uniprot.org/uniprot/A0A0M4CY91 ^@ Cofactor|||Function|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.|||Homodimer. http://togogenome.org/gene/931089:CDES_RS04110 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS07625 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Q3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/931089:CDES_RS10110 ^@ http://purl.uniprot.org/uniprot/A0A0M4CR09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS04350 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWX3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/931089:CDES_RS02370 ^@ http://purl.uniprot.org/uniprot/A0A0M4CN60 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Could possibly oxidize fatty acids using specific components.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS01705 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Z8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/931089:CDES_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGW4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/931089:CDES_RS10430 ^@ http://purl.uniprot.org/uniprot/A0A0M5IUE4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS07705 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9N6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/931089:CDES_RS07590 ^@ http://purl.uniprot.org/uniprot/A0A0M5IG74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS08755 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS09580 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEP0 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/931089:CDES_RS11350 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYY6 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/931089:CDES_RS14485 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHR5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS06130 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9H3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A0M5IUE0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/931089:CDES_RS11580 ^@ http://purl.uniprot.org/uniprot/A0A0M4CRJ4 ^@ Function ^@ Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). http://togogenome.org/gene/931089:CDES_RS03485 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEU4 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/931089:CDES_RS08190 ^@ http://purl.uniprot.org/uniprot/A0A0M5IR86 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/931089:CDES_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q950 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/931089:CDES_RS08650 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9S0 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/931089:CDES_RS09530 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQU2 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/931089:CDES_RS09655 ^@ http://purl.uniprot.org/uniprot/A0A0M5IGE2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/931089:CDES_RS10005 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJE4 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/931089:CDES_RS04640 ^@ http://purl.uniprot.org/uniprot/A0A0M4CP43 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/931089:CDES_RS04440 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9B5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS06710 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9J5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/931089:CDES_RS11125 ^@ http://purl.uniprot.org/uniprot/A0A0M5IGH1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/931089:CDES_RS04215 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNY8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/931089:CDES_RS01380 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q902 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/931089:CDES_RS05610 ^@ http://purl.uniprot.org/uniprot/A0A0M5IR05 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS08550 ^@ http://purl.uniprot.org/uniprot/A0A0M5IU92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS00605 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS07605 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9N2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/931089:CDES_RS11680 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZ27 ^@ Function|||Similarity ^@ Belongs to the IMPDH/GMPR family. GuaB1 subfamily.|||Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP. http://togogenome.org/gene/931089:CDES_RS12100 ^@ http://purl.uniprot.org/uniprot/A0A0M5IUJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/931089:CDES_RS09955 ^@ http://purl.uniprot.org/uniprot/A0A0M5IJ89 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/931089:CDES_RS07025 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLV0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.|||Monomer. http://togogenome.org/gene/931089:CDES_RS08775 ^@ http://purl.uniprot.org/uniprot/A0A0M4CK13 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/931089:CDES_RS13585 ^@ http://purl.uniprot.org/uniprot/A0A0M4CP35 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/931089:CDES_RS10945 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHI9 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/931089:CDES_RS11420 ^@ http://purl.uniprot.org/uniprot/A0A0M4CL00 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/931089:CDES_RS07820 ^@ http://purl.uniprot.org/uniprot/A0A0M4CY99 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/931089:CDES_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEI6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/931089:CDES_RS02275 ^@ http://purl.uniprot.org/uniprot/A0A0M5II83 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS08505 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9R4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/931089:CDES_RS08445 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMB7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS12170 ^@ http://purl.uniprot.org/uniprot/A0A0M5IUR1 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/931089:CDES_RS09705 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Z3 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/931089:CDES_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q920 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/931089:CDES_RS07965 ^@ http://purl.uniprot.org/uniprot/A0A0M4CM65 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/931089:CDES_RS04225 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9A8 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/931089:CDES_RS02555 ^@ http://purl.uniprot.org/uniprot/A0A0M5IFS2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/931089:CDES_RS08270 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9S6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/931089:CDES_RS02640 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q947 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/931089:CDES_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A0M4CUY3 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/931089:CDES_RS08000 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS06430 ^@ http://purl.uniprot.org/uniprot/A0A0M5IP80 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/931089:CDES_RS03570 ^@ http://purl.uniprot.org/uniprot/A0A0M5IP06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS01185 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8X8 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/931089:CDES_RS08325 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9S8 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/931089:CDES_RS03400 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH91 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/931089:CDES_RS01955 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGT9 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/931089:CDES_RS05355 ^@ http://purl.uniprot.org/uniprot/A0A0M5IG04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS09370 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9X9 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/931089:CDES_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q981 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS04560 ^@ http://purl.uniprot.org/uniprot/A0A0M4CF83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS10940 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8X0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Gfo/Idh/MocA family.|||Homotetramer.|||Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose). http://togogenome.org/gene/931089:CDES_RS06150 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJ47 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/931089:CDES_RS01595 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVS1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/931089:CDES_RS11975 ^@ http://purl.uniprot.org/uniprot/A0A0M5IGL1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/931089:CDES_RS06170 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPN9 ^@ Similarity ^@ Belongs to the dihydropyrimidine dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS03525 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKM3 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/931089:CDES_RS01330 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q901 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/931089:CDES_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHL2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS02505 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/931089:CDES_RS02945 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEM9 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/931089:CDES_RS02165 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS05350 ^@ http://purl.uniprot.org/uniprot/A0A0M4CL97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A0M4CE59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/931089:CDES_RS10245 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZ74 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/931089:CDES_RS05500 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFK8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS04145 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9A3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS07030 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9M7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGI1 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/931089:CDES_RS11560 ^@ http://purl.uniprot.org/uniprot/A0A0M4CL15 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS11715 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZR0 ^@ Similarity ^@ Belongs to the pantothenate synthetase family. http://togogenome.org/gene/931089:CDES_RS02270 ^@ http://purl.uniprot.org/uniprot/A0A0M4CK68 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/931089:CDES_RS11605 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS13225 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZN8 ^@ Cofactor|||Similarity ^@ Belongs to the anthranilate synthase component I family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/931089:CDES_RS06610 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFZ5 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS07500 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILN6 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/931089:CDES_RS11600 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS03880 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/931089:CDES_RS10995 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/931089:CDES_RS02050 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEB8 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/931089:CDES_RS02655 ^@ http://purl.uniprot.org/uniprot/A0A0M5INX8 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/931089:CDES_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/931089:CDES_RS05180 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWJ8 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/931089:CDES_RS08490 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILR6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/931089:CDES_RS06530 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJ91 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS11020 ^@ http://purl.uniprot.org/uniprot/A0A0M4CF42 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS11155 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHL3 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/931089:CDES_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMT3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CobB/CobQ family. GatD subfamily.|||Forms a heterodimer with MurT.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT. http://togogenome.org/gene/931089:CDES_RS02705 ^@ http://purl.uniprot.org/uniprot/A0A0M5IFT1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/931089:CDES_RS00005 ^@ http://purl.uniprot.org/uniprot/A0A0M5ITP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/931089:CDES_RS02740 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVJ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/931089:CDES_RS10345 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHA3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/931089:CDES_RS03390 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILB1 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/931089:CDES_RS10735 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHF5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS10780 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Z6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS01040 ^@ http://purl.uniprot.org/uniprot/A0A0M4CC41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS03405 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q976 ^@ Function|||Similarity ^@ Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.|||Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. http://togogenome.org/gene/931089:CDES_RS04230 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWV6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/931089:CDES_RS13175 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLL9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS02900 ^@ http://purl.uniprot.org/uniprot/A0A0M5ITY0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/931089:CDES_RS12070 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZ78 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/931089:CDES_RS04485 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/931089:CDES_RS02030 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIJ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS10150 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKJ1 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/931089:CDES_RS08200 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXQ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/931089:CDES_RS11550 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA24 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS02465 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q932 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/931089:CDES_RS13445 ^@ http://purl.uniprot.org/uniprot/A0A0M4CS67 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/931089:CDES_RS12960 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNW5 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS09405 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS06110 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXM8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/931089:CDES_RS13485 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/931089:CDES_RS04245 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9A7 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/931089:CDES_RS04205 ^@ http://purl.uniprot.org/uniprot/A0A0M4CF35 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/931089:CDES_RS02750 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/931089:CDES_RS03480 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI95 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS07375 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9P2 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS01590 ^@ http://purl.uniprot.org/uniprot/A0A0M5ITM6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/931089:CDES_RS09385 ^@ http://purl.uniprot.org/uniprot/A0A0M4CY75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell membrane|||Essential cell division protein. http://togogenome.org/gene/931089:CDES_RS01515 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Z0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/931089:CDES_RS12025 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFF4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS01360 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Y4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/931089:CDES_RS09075 ^@ http://purl.uniprot.org/uniprot/A0A0M4CK56 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/931089:CDES_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A0M4CBY4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS04650 ^@ http://purl.uniprot.org/uniprot/A0A0M4CX18 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.|||Belongs to the MshB deacetylase family. Mca subfamily.|||Binds 1 zinc ion per subunit.|||Monomer. http://togogenome.org/gene/931089:CDES_RS05905 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI29 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS05660 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/931089:CDES_RS05305 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS13440 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFV3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS03115 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVP5 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/931089:CDES_RS11900 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFD8 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/931089:CDES_RS04050 ^@ http://purl.uniprot.org/uniprot/A0A0M5IQW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS08520 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXV3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/931089:CDES_RS02500 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHY1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/931089:CDES_RS01530 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVR2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS07790 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJP1 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/931089:CDES_RS09650 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQV6 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/931089:CDES_RS08765 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXY4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/931089:CDES_RS01830 ^@ http://purl.uniprot.org/uniprot/A0A0M5IL70 ^@ Function|||Similarity ^@ Belongs to the catalase family. HPII subfamily.|||Serves to protect cells from the toxic effects of hydrogen peroxide. http://togogenome.org/gene/931089:CDES_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLE1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/931089:CDES_RS01130 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8X6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS11775 ^@ http://purl.uniprot.org/uniprot/A0A0M5IUI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/931089:CDES_RS05620 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWQ8 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/931089:CDES_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI71 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS02310 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q938 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS13455 ^@ http://purl.uniprot.org/uniprot/A0A0M4D0F7 ^@ Function ^@ Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. http://togogenome.org/gene/931089:CDES_RS04185 ^@ http://purl.uniprot.org/uniprot/A0A0M5IID9 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/931089:CDES_RS06985 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJE2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS04665 ^@ http://purl.uniprot.org/uniprot/A0A0M4CL09 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS02590 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q945 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS00065 ^@ http://purl.uniprot.org/uniprot/A0A0M5INQ3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/931089:CDES_RS07730 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJN3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/931089:CDES_RS01735 ^@ http://purl.uniprot.org/uniprot/A0A0M4CV34 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/931089:CDES_RS04125 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9A4 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/931089:CDES_RS05885 ^@ http://purl.uniprot.org/uniprot/A0A0M4CDL8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/931089:CDES_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q933 ^@ Function|||Similarity ^@ Belongs to the bacterial two-domain DSD family.|||Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways. http://togogenome.org/gene/931089:CDES_RS06115 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/931089:CDES_RS06780 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS10915 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJQ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/931089:CDES_RS10235 ^@ http://purl.uniprot.org/uniprot/A0A0M4CR25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/931089:CDES_RS11970 ^@ http://purl.uniprot.org/uniprot/A0A0M4CRP2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/931089:CDES_RS05005 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIR0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS06970 ^@ http://purl.uniprot.org/uniprot/A0A0M5IG55 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/931089:CDES_RS02450 ^@ http://purl.uniprot.org/uniprot/A0A0M4CCJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/931089:CDES_RS08370 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYG3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/931089:CDES_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIY4 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/931089:CDES_RS09400 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS04680 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9D1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS06305 ^@ http://purl.uniprot.org/uniprot/A0A0M5IU18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS07615 ^@ http://purl.uniprot.org/uniprot/A0A0M4CE39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS03735 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEX6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/931089:CDES_RS10440 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJJ9 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/931089:CDES_RS00425 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UreE family.|||Cytoplasm|||Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. http://togogenome.org/gene/931089:CDES_RS10540 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEZ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS00450 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHC5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS06195 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLK4 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/931089:CDES_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNG3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/931089:CDES_RS06425 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPU9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/931089:CDES_RS02755 ^@ http://purl.uniprot.org/uniprot/A0A0M4CCM1 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/931089:CDES_RS03510 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWK6 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/931089:CDES_RS08365 ^@ http://purl.uniprot.org/uniprot/A0A0M5IPD6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS07120 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9L1 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/931089:CDES_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILE2 ^@ Similarity ^@ Belongs to the transglycosylase family. Rpf subfamily. http://togogenome.org/gene/931089:CDES_RS03600 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q984 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/931089:CDES_RS06750 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS12755 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZI3 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/931089:CDES_RS07645 ^@ http://purl.uniprot.org/uniprot/A0A0M4CM31 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/931089:CDES_RS04105 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWT6 ^@ Similarity ^@ Belongs to the dihydrofolate reductase family. http://togogenome.org/gene/931089:CDES_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVG4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS06165 ^@ http://purl.uniprot.org/uniprot/A0A0M4CDQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS03125 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEQ2 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/931089:CDES_RS04600 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILT9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/931089:CDES_RS10050 ^@ http://purl.uniprot.org/uniprot/A0A0M4CR01 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IPP isomerase type 1 family.|||Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS09930 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA01 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS11310 ^@ http://purl.uniprot.org/uniprot/A0A0M4CF75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS01030 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8X2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS07970 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIR0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/931089:CDES_RS00730 ^@ http://purl.uniprot.org/uniprot/A0A0M4CML4 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/931089:CDES_RS13580 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKM5 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/931089:CDES_RS02550 ^@ http://purl.uniprot.org/uniprot/A0A0M4CK99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/931089:CDES_RS12930 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS07830 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIP5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS06470 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJ84 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/931089:CDES_RS03090 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWE5 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/931089:CDES_RS11430 ^@ http://purl.uniprot.org/uniprot/A0A0M4CF87 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS08925 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMH6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/931089:CDES_RS10910 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA38 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/931089:CDES_RS02710 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q944 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/931089:CDES_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9E9 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/931089:CDES_RS06055 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9J0 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/931089:CDES_RS09945 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/931089:CDES_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A0M4CW03 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/931089:CDES_RS08040 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXP2 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS04805 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS11240 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA12 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/931089:CDES_RS04660 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9C4 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/931089:CDES_RS08565 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIW6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/931089:CDES_RS07620 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQ82 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/931089:CDES_RS02390 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q930 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family. MenD subfamily.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).|||Homodimer. http://togogenome.org/gene/931089:CDES_RS09210 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGW6 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/931089:CDES_RS04490 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9B7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/931089:CDES_RS07985 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJR2 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/931089:CDES_RS08785 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEF9 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/931089:CDES_RS05865 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWU6 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/931089:CDES_RS06235 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILJ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/931089:CDES_RS13490 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIE6 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/931089:CDES_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A0M4CD32 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/931089:CDES_RS09745 ^@ http://purl.uniprot.org/uniprot/A0A0M5IRD3 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/931089:CDES_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q940 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/931089:CDES_RS13085 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNX9 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/931089:CDES_RS05715 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein SsuA/TauA family.|||Periplasm http://togogenome.org/gene/931089:CDES_RS13235 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIB6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS06955 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIF1 ^@ Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily. http://togogenome.org/gene/931089:CDES_RS08145 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Q0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ChdC family. Type 2 subfamily.|||Fe-coproporphyrin III acts as both substrate and redox cofactor.|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate. http://togogenome.org/gene/931089:CDES_RS12215 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHZ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS04255 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIH8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/931089:CDES_RS00850 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS09975 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH57 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/931089:CDES_RS05100 ^@ http://purl.uniprot.org/uniprot/A0A0M4CX77 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/931089:CDES_RS11080 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKV9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/931089:CDES_RS04025 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILD3 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/931089:CDES_RS12140 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZ89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS13250 ^@ http://purl.uniprot.org/uniprot/A0A0M4CS49 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/931089:CDES_RS03720 ^@ http://purl.uniprot.org/uniprot/A0A0M5IQV2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/931089:CDES_RS05220 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHU1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/931089:CDES_RS09980 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/931089:CDES_RS10595 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYN8 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/931089:CDES_RS08905 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGS5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/931089:CDES_RS03820 ^@ http://purl.uniprot.org/uniprot/A0A0M5IU12 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/931089:CDES_RS04740 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWD3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/931089:CDES_RS02420 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEG5 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/931089:CDES_RS03800 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEY4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/931089:CDES_RS10640 ^@ http://purl.uniprot.org/uniprot/A0A0M4CN47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS00800 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Y1 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/931089:CDES_RS02765 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNB6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/931089:CDES_RS11845 ^@ http://purl.uniprot.org/uniprot/A0A0M5IUQ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS01125 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGK9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/931089:CDES_RS13065 ^@ http://purl.uniprot.org/uniprot/A0A0M3QAC1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS03235 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS05685 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9H6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NucS endonuclease family.|||Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS10340 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKL5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/931089:CDES_RS08960 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEH7 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/931089:CDES_RS13335 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS06535 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS11615 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZ19 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS09215 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9X3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS06685 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPX8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.|||Cell membrane|||Mediates zinc uptake. May also transport other divalent cations.|||Membrane http://togogenome.org/gene/931089:CDES_RS09620 ^@ http://purl.uniprot.org/uniprot/A0A0M5IJ78 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS04550 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIL4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A0M4CND5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/931089:CDES_RS09785 ^@ http://purl.uniprot.org/uniprot/A0A0M5IUC5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS03910 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/931089:CDES_RS02865 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q951 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS08740 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/931089:CDES_RS02670 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q942 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/931089:CDES_RS10560 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/931089:CDES_RS02940 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI30 ^@ Similarity ^@ Belongs to the AAE transporter (TC 2.A.81) family. http://togogenome.org/gene/931089:CDES_RS12425 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNQ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS08330 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIR9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS00305 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8U5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS12520 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFK9 ^@ Similarity ^@ Belongs to the FAD-binding monooxygenase family. http://togogenome.org/gene/931089:CDES_RS02040 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHS9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS12105 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZW4 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/931089:CDES_RS11265 ^@ http://purl.uniprot.org/uniprot/A0A0M5IPM6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/931089:CDES_RS07595 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXI5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/931089:CDES_RS12920 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLI7 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/931089:CDES_RS04965 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILG1 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/931089:CDES_RS01680 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJZ6 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/931089:CDES_RS02665 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH09 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/931089:CDES_RS00670 ^@ http://purl.uniprot.org/uniprot/A0A0M5ITR8 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/931089:CDES_RS12705 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFN2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by fructose 1,6-bisphosphate (FBP).|||Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/931089:CDES_RS01635 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHN3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS08805 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIZ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/931089:CDES_RS02175 ^@ http://purl.uniprot.org/uniprot/A0A0M4CCF9 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/931089:CDES_RS02790 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH24 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/931089:CDES_RS10680 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA31 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/931089:CDES_RS04785 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9D5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/931089:CDES_RS04270 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9B0 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/931089:CDES_RS13600 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZT8 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/931089:CDES_RS02985 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIM5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/931089:CDES_RS00265 ^@ http://purl.uniprot.org/uniprot/A0A0M4CBW3 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/931089:CDES_RS09755 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Z5 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/931089:CDES_RS12280 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA90 ^@ Caution|||Similarity ^@ Belongs to the globin family.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS09605 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Y9 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/931089:CDES_RS00025 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8T4 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/931089:CDES_RS10490 ^@ http://purl.uniprot.org/uniprot/A0A0M5IUL1 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/931089:CDES_RS00420 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVC0 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/931089:CDES_RS00050 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8V4 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/931089:CDES_RS13240 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFT4 ^@ Function|||Similarity ^@ Belongs to the TrpF family.|||Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.|||In the C-terminal section; belongs to the TrpF family.|||In the N-terminal section; belongs to the TrpC family. http://togogenome.org/gene/931089:CDES_RS01355 ^@ http://purl.uniprot.org/uniprot/A0A0M5II54 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS06410 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFX0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/931089:CDES_RS03005 ^@ http://purl.uniprot.org/uniprot/A0A0M4CCQ3 ^@ Similarity ^@ Belongs to the IMPDH/GMPR family. http://togogenome.org/gene/931089:CDES_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q946 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/931089:CDES_RS07670 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGC4 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/931089:CDES_RS10080 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA07 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/931089:CDES_RS01250 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Y0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/931089:CDES_RS03665 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVX4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/931089:CDES_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9E5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS08450 ^@ http://purl.uniprot.org/uniprot/A0A0M5IM47 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/931089:CDES_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Y9 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/931089:CDES_RS07565 ^@ http://purl.uniprot.org/uniprot/A0A0M5IU54 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS02825 ^@ http://purl.uniprot.org/uniprot/A0A0M4CCN1 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/931089:CDES_RS06125 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS13090 ^@ http://purl.uniprot.org/uniprot/A0A0M5IGM9 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/931089:CDES_RS12005 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZ69 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS11390 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZL7 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/931089:CDES_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXG8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/931089:CDES_RS03575 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWL3 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/931089:CDES_RS09120 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMK0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/931089:CDES_RS11570 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA62 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/931089:CDES_RS09200 ^@ http://purl.uniprot.org/uniprot/A0A0M4CY51 ^@ Similarity ^@ Belongs to the HSP15 family. http://togogenome.org/gene/931089:CDES_RS06400 ^@ http://purl.uniprot.org/uniprot/A0A0M4CX21 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS11960 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFE6 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/931089:CDES_RS09500 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/931089:CDES_RS07675 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Q5 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/931089:CDES_RS03305 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q972 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/931089:CDES_RS02205 ^@ http://purl.uniprot.org/uniprot/A0A0M4CK62 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS09380 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/931089:CDES_RS08895 ^@ http://purl.uniprot.org/uniprot/A0A0M4CK33 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/931089:CDES_RS13015 ^@ http://purl.uniprot.org/uniprot/A0A0M3QAB9 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/931089:CDES_RS03780 ^@ http://purl.uniprot.org/uniprot/A0A0M5IFW0 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/931089:CDES_RS03285 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/931089:CDES_RS00815 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS06825 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXW4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/931089:CDES_RS13025 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNX3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS04315 ^@ http://purl.uniprot.org/uniprot/A0A0M4CII4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Belongs to the precorrin methyltransferase family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS10660 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Z2 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/931089:CDES_RS00130 ^@ http://purl.uniprot.org/uniprot/A0A0M4CDP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A0M5IR96 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/931089:CDES_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLB7 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/931089:CDES_RS05120 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9D8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/931089:CDES_RS02960 ^@ http://purl.uniprot.org/uniprot/A0A0M5INY5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/931089:CDES_RS05235 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILV4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/931089:CDES_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWS9 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/931089:CDES_RS00830 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8W3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/931089:CDES_RS11670 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA65 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/931089:CDES_RS10405 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Y2 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/931089:CDES_RS09640 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH18 ^@ Similarity ^@ Belongs to the AAE transporter (TC 2.A.81) family. http://togogenome.org/gene/931089:CDES_RS02480 ^@ http://purl.uniprot.org/uniprot/A0A0M4CK90 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMG2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS08470 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGM1 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/931089:CDES_RS07775 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Q9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS10040 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH64 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/931089:CDES_RS09760 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS11440 ^@ http://purl.uniprot.org/uniprot/A0A0M4CRI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS06995 ^@ http://purl.uniprot.org/uniprot/A0A0M4CDX8 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. http://togogenome.org/gene/931089:CDES_RS04970 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9D2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 3 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS03410 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKK8 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/931089:CDES_RS09970 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKG5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/931089:CDES_RS10450 ^@ http://purl.uniprot.org/uniprot/A0A0M5IGF1 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/931089:CDES_RS12735 ^@ http://purl.uniprot.org/uniprot/A0A0M3QAA3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS12305 ^@ http://purl.uniprot.org/uniprot/A0A0M5IMF8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS08350 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/931089:CDES_RS08850 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9S9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/931089:CDES_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWU4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/931089:CDES_RS11325 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZK9 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/931089:CDES_RS00330 ^@ http://purl.uniprot.org/uniprot/A0A0M4CBW9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/931089:CDES_RS06220 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFU6 ^@ Similarity ^@ Belongs to the helicase family. RecG subfamily. http://togogenome.org/gene/931089:CDES_RS05200 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPB7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/931089:CDES_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9P6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS10520 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYN0 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/931089:CDES_RS10905 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZG2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS00320 ^@ http://purl.uniprot.org/uniprot/A0A0M4CDR9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS09695 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKD1 ^@ Similarity ^@ Belongs to the heme oxygenase family. http://togogenome.org/gene/931089:CDES_RS00805 ^@ http://purl.uniprot.org/uniprot/A0A0M5IFM4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS13615 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/931089:CDES_RS07630 ^@ http://purl.uniprot.org/uniprot/A0A0M5IUC3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS08250 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Q4 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/931089:CDES_RS04000 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/931089:CDES_RS04290 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9A9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS09665 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJA4 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/931089:CDES_RS04420 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9B6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS05445 ^@ http://purl.uniprot.org/uniprot/A0A0M4CDG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS04385 ^@ http://purl.uniprot.org/uniprot/A0A0M4CF59 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/931089:CDES_RS10625 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS06250 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS06330 ^@ http://purl.uniprot.org/uniprot/A0A0M5IG37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS08830 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXZ5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/931089:CDES_RS09115 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJ30 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/931089:CDES_RS05645 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPH3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/931089:CDES_RS11025 ^@ http://purl.uniprot.org/uniprot/A0A0M4CRB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS11275 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJU7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the acetyltransferase family. MshD subfamily.|||Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/931089:CDES_RS02720 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/931089:CDES_RS06745 ^@ http://purl.uniprot.org/uniprot/A0A0M4CDV3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS05920 ^@ http://purl.uniprot.org/uniprot/A0A0M5IR15 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/931089:CDES_RS10030 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA05 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/931089:CDES_RS12760 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLH2 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/931089:CDES_RS01280 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGM4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon. http://togogenome.org/gene/931089:CDES_RS07835 ^@ http://purl.uniprot.org/uniprot/A0A0M4CM51 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/931089:CDES_RS09875 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Z9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS08240 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYE7 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/931089:CDES_RS09700 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH26 ^@ Function|||Similarity ^@ Belongs to the GlnE family.|||Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell. http://togogenome.org/gene/931089:CDES_RS01755 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q900 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS01255 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMS6 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/931089:CDES_RS03155 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/931089:CDES_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVU9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/931089:CDES_RS08405 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9R0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/931089:CDES_RS12925 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI82 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/931089:CDES_RS07085 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXZ7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/931089:CDES_RS06450 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS03335 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWI2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS04780 ^@ http://purl.uniprot.org/uniprot/A0A0M4CX35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/931089:CDES_RS02935 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q958 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD. http://togogenome.org/gene/931089:CDES_RS10305 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9X8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS03920 ^@ http://purl.uniprot.org/uniprot/A0A0M4CW14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/931089:CDES_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIK5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/931089:CDES_RS08410 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9F7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS07975 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/931089:CDES_RS08945 ^@ http://purl.uniprot.org/uniprot/A0A0M4CK40 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/931089:CDES_RS07055 ^@ http://purl.uniprot.org/uniprot/A0A0M4CDY6 ^@ Similarity ^@ Belongs to the UPF0098 family. http://togogenome.org/gene/931089:CDES_RS11035 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZH8 ^@ Function|||Similarity ^@ Belongs to the NrdI family.|||Probably involved in ribonucleotide reductase function. http://togogenome.org/gene/931089:CDES_RS08570 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9T5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/931089:CDES_RS11525 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS03640 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWM0 ^@ Cofactor|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/931089:CDES_RS03220 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH70 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/931089:CDES_RS02215 ^@ http://purl.uniprot.org/uniprot/A0A0M5IFR0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/931089:CDES_RS08560 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYI7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/931089:CDES_RS08235 ^@ http://purl.uniprot.org/uniprot/A0A0M5IU75 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEB0 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/931089:CDES_RS06595 ^@ http://purl.uniprot.org/uniprot/A0A0M4CX48 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/931089:CDES_RS04005 ^@ http://purl.uniprot.org/uniprot/A0A0M4CF07 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/931089:CDES_RS10510 ^@ http://purl.uniprot.org/uniprot/A0A0M4CN30 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/931089:CDES_RS07715 ^@ http://purl.uniprot.org/uniprot/A0A0M5IJ23 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/931089:CDES_RS09420 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILU5 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS11040 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJS3 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/931089:CDES_RS06525 ^@ http://purl.uniprot.org/uniprot/A0A0M4CX39 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/931089:CDES_RS01950 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVY6 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/931089:CDES_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9I6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS10565 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJL5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/931089:CDES_RS12955 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKF4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/931089:CDES_RS05825 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPJ4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS08605 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQI2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS06830 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS12530 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA96 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/931089:CDES_RS05995 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJ25 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/931089:CDES_RS07770 ^@ http://purl.uniprot.org/uniprot/A0A0M4CM45 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/931089:CDES_RS12765 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA74 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/931089:CDES_RS06590 ^@ http://purl.uniprot.org/uniprot/A0A0M5IR37 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS10715 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYQ7 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/931089:CDES_RS05850 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLG1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbsD / FucU family. RbsD subfamily.|||Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.|||Cytoplasm|||Homodecamer. http://togogenome.org/gene/931089:CDES_RS02125 ^@ http://purl.uniprot.org/uniprot/A0A0M4CN24 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/931089:CDES_RS02565 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/931089:CDES_RS03450 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q978 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/931089:CDES_RS02890 ^@ http://purl.uniprot.org/uniprot/A0A0M4CCP0 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/931089:CDES_RS10170 ^@ http://purl.uniprot.org/uniprot/A0A0M4CR18 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the malate synthase family. GlcB subfamily.|||Cytoplasm|||Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/931089:CDES_RS02905 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWB8 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/931089:CDES_RS09940 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZ26 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/931089:CDES_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EccD/Snm4 family.|||Membrane http://togogenome.org/gene/931089:CDES_RS11765 ^@ http://purl.uniprot.org/uniprot/A0A0M4CRL9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/931089:CDES_RS10415 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEY0 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/931089:CDES_RS11620 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA64 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/931089:CDES_RS10855 ^@ http://purl.uniprot.org/uniprot/A0A0M4CN71 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS09005 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9W5 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/931089:CDES_RS00465 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8V0 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/931089:CDES_RS00415 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8U8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/931089:CDES_RS07560 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQ74 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/931089:CDES_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A0M4CY58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS11850 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS01760 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMX9 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/931089:CDES_RS01565 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Z2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS10805 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BCCT transporter (TC 2.A.15) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS11090 ^@ http://purl.uniprot.org/uniprot/A0A0M4CF49 ^@ Similarity ^@ Belongs to the D-glutamate cyclase family. http://togogenome.org/gene/931089:CDES_RS11650 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA28 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DisA family.|||Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.|||Homooctamer.|||Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. http://togogenome.org/gene/931089:CDES_RS05515 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPF2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS01525 ^@ http://purl.uniprot.org/uniprot/A0A0M5IL61 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. PCD1 subfamily. http://togogenome.org/gene/931089:CDES_RS00290 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A0M4CI18 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/931089:CDES_RS09355 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS10320 ^@ http://purl.uniprot.org/uniprot/A0A0M4CN05 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/931089:CDES_RS03085 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILA2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS07000 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQ13 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/931089:CDES_RS03835 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0182 family.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS13610 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIG2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/931089:CDES_RS11105 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS10190 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BCCT transporter (TC 2.A.15) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS10285 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH97 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/931089:CDES_RS10970 ^@ http://purl.uniprot.org/uniprot/A0A0M5IGI1 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/931089:CDES_RS04685 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIM8 ^@ Similarity ^@ In the C-terminal section; belongs to the anthranilate synthase component I family. http://togogenome.org/gene/931089:CDES_RS05795 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIV9 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/931089:CDES_RS03200 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNI9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A0M4CX86 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.|||Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/931089:CDES_RS07690 ^@ http://purl.uniprot.org/uniprot/A0A0M5IPB6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS05810 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9G4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/931089:CDES_RS07540 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS12085 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA82 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS11950 ^@ http://purl.uniprot.org/uniprot/A0A0M4CL64 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/931089:CDES_RS13430 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLP8 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase family. http://togogenome.org/gene/931089:CDES_RS09415 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9Y1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/931089:CDES_RS01430 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q904 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS05900 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS02460 ^@ http://purl.uniprot.org/uniprot/A0A0M5IL87 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/931089:CDES_RS07760 ^@ http://purl.uniprot.org/uniprot/A0A0M4CY92 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/931089:CDES_RS01195 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGL6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/931089:CDES_RS06555 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILL0 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/931089:CDES_RS05655 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXF9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/931089:CDES_RS11740 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZ36 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/931089:CDES_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9F2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/931089:CDES_RS07920 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJQ7 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGB5 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/931089:CDES_RS06655 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9J3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS11425 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHP7 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/931089:CDES_RS05545 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLC6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/931089:CDES_RS08790 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQK4 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/931089:CDES_RS00435 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8W7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/931089:CDES_RS01230 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS09595 ^@ http://purl.uniprot.org/uniprot/A0A0M5IPH4 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/931089:CDES_RS05150 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/931089:CDES_RS05520 ^@ http://purl.uniprot.org/uniprot/A0A0M5IG18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS07925 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGF7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS13120 ^@ http://purl.uniprot.org/uniprot/A0A0M3QAC3 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/931089:CDES_RS03330 ^@ http://purl.uniprot.org/uniprot/A0A0M5IFU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/931089:CDES_RS10770 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZE3 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/931089:CDES_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS05840 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS11645 ^@ http://purl.uniprot.org/uniprot/A0A0M5IGK3 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/931089:CDES_RS08810 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/931089:CDES_RS12350 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZZ8 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/931089:CDES_RS05860 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9G5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS08425 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9T2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS10825 ^@ http://purl.uniprot.org/uniprot/A0A0M4CF18 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/931089:CDES_RS08690 ^@ http://purl.uniprot.org/uniprot/A0A0M4CME5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9G0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. http://togogenome.org/gene/931089:CDES_RS03340 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVS9 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/931089:CDES_RS04815 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9C7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS08670 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9T7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/931089:CDES_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEL1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/931089:CDES_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A0M5IID0 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/931089:CDES_RS05990 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWW5 ^@ Similarity ^@ Belongs to the isochorismate synthase family. http://togogenome.org/gene/931089:CDES_RS00750 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGH2 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/931089:CDES_RS04765 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9C6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJ01 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/931089:CDES_RS08495 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYH9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/931089:CDES_RS06790 ^@ http://purl.uniprot.org/uniprot/A0A0M4CX75 ^@ Function|||Similarity ^@ Belongs to the Thz kinase family.|||Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). http://togogenome.org/gene/931089:CDES_RS00440 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIE2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreD family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/931089:CDES_RS11890 ^@ http://purl.uniprot.org/uniprot/A0A0M4CL54 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/931089:CDES_RS02305 ^@ http://purl.uniprot.org/uniprot/A0A0M4CN52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS11260 ^@ http://purl.uniprot.org/uniprot/A0A0M3QA50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/931089:CDES_RS09055 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMJ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS11875 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZ50 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/931089:CDES_RS01560 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS12095 ^@ http://purl.uniprot.org/uniprot/A0A0M4CRQ6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/931089:CDES_RS07650 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIP9 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/931089:CDES_RS02830 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNC3 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/931089:CDES_RS04220 ^@ http://purl.uniprot.org/uniprot/A0A0M5IP18 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/931089:CDES_RS01320 ^@ http://purl.uniprot.org/uniprot/A0A0M4CC67 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/931089:CDES_RS02835 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q954 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS00680 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVF1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS10010 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9W6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS12740 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKD7 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS08575 ^@ http://purl.uniprot.org/uniprot/A0A0M5IG99 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/931089:CDES_RS05030 ^@ http://purl.uniprot.org/uniprot/A0A0M5ITX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS05560 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIW8 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS06760 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9J7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/931089:CDES_RS08940 ^@ http://purl.uniprot.org/uniprot/A0A0M4CY12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS06190 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9H5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/931089:CDES_RS12110 ^@ http://purl.uniprot.org/uniprot/A0A0M4CK49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS11145 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYV5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS05420 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS01180 ^@ http://purl.uniprot.org/uniprot/A0A0M5IL52 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/931089:CDES_RS09950 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMV2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS06880 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9M2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS06585 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLP9 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/931089:CDES_RS03885 ^@ http://purl.uniprot.org/uniprot/A0A0M5IP08 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/931089:CDES_RS03345 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS10815 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKS4 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/931089:CDES_RS06965 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLU2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/931089:CDES_RS02475 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGY9 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/931089:CDES_RS02455 ^@ http://purl.uniprot.org/uniprot/A0A0M4CN70 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/931089:CDES_RS05925 ^@ http://purl.uniprot.org/uniprot/A0A0M4CWV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/931089:CDES_RS03290 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/931089:CDES_RS06650 ^@ http://purl.uniprot.org/uniprot/A0A0M5IG45 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/931089:CDES_RS09570 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKB4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with subunits I, II and III to form cytochrome c oxidase.|||Belongs to the cytochrome c oxidase bacterial subunit CtaF family.|||Cell membrane|||Membrane|||Part of cytochrome c oxidase, its function is unknown. http://togogenome.org/gene/931089:CDES_RS01675 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Z6 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/931089:CDES_RS05615 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9F9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/931089:CDES_RS01315 ^@ http://purl.uniprot.org/uniprot/A0A0M4CE29 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/931089:CDES_RS09775 ^@ http://purl.uniprot.org/uniprot/A0A0M4CER1 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/931089:CDES_RS08290 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEA4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/931089:CDES_RS03690 ^@ http://purl.uniprot.org/uniprot/A0A0M5ILC3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/931089:CDES_RS01340 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVN2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS00710 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHF0 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/931089:CDES_RS02055 ^@ http://purl.uniprot.org/uniprot/A0A0M4CCE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS01765 ^@ http://purl.uniprot.org/uniprot/A0A0M5IFQ1 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/931089:CDES_RS06805 ^@ http://purl.uniprot.org/uniprot/A0A0M4CDW0 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS09070 ^@ http://purl.uniprot.org/uniprot/A0A0M4CY32 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS08165 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9S2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/931089:CDES_RS10850 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJP6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/931089:CDES_RS03615 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEW0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/931089:CDES_RS01800 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHQ0 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/931089:CDES_RS07720 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXK0 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS12160 ^@ http://purl.uniprot.org/uniprot/A0A0M4CFG6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS08970 ^@ http://purl.uniprot.org/uniprot/A0A0M5IPF6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/931089:CDES_RS09575 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH10 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/931089:CDES_RS09545 ^@ http://purl.uniprot.org/uniprot/A0A0M4CYX3 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/931089:CDES_RS00640 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8X5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinone-dependent D-lactate dehydrogenase family.|||Catalyzes the oxidation of D-lactate to pyruvate.|||Cell membrane http://togogenome.org/gene/931089:CDES_RS05880 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9I4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LysE/ArgO transporter (TC 2.A.75) family.|||Membrane http://togogenome.org/gene/931089:CDES_RS10755 ^@ http://purl.uniprot.org/uniprot/A0A0M4CR83 ^@ Cofactor|||Similarity ^@ Belongs to the alkaline phosphatase family.|||Binds 1 Mg(2+) ion.|||Binds 2 Zn(2+) ions. http://togogenome.org/gene/931089:CDES_RS08590 ^@ http://purl.uniprot.org/uniprot/A0A0M4CGN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q8Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS07665 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJM5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/931089:CDES_RS03080 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q963 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A0M4CE46 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/931089:CDES_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A0M4CN99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/931089:CDES_RS05675 ^@ http://purl.uniprot.org/uniprot/A0A0M5IG15 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/931089:CDES_RS07825 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9R1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS11085 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHK4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/931089:CDES_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJG9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/931089:CDES_RS13695 ^@ http://purl.uniprot.org/uniprot/A0A0M4CP46 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS12975 ^@ http://purl.uniprot.org/uniprot/A0A0M4CZK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/931089:CDES_RS10500 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJK7 ^@ Similarity|||Subunit ^@ Belongs to the muconolactone Delta-isomerase family.|||Homodecamer. http://togogenome.org/gene/931089:CDES_RS12820 ^@ http://purl.uniprot.org/uniprot/A0A0M4CLH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/931089:CDES_RS03630 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNQ2 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/931089:CDES_RS05665 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9G1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/931089:CDES_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 85 family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS09805 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMT5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Acyl carrier protein involved in meromycolate extension.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/931089:CDES_RS00220 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVA6 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/931089:CDES_RS07745 ^@ http://purl.uniprot.org/uniprot/A0A0M4CQ97 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/931089:CDES_RS11710 ^@ http://purl.uniprot.org/uniprot/A0A0M5IM09 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS09240 ^@ http://purl.uniprot.org/uniprot/A0A0M4CJ46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/931089:CDES_RS09495 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q9V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/931089:CDES_RS07515 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIL3 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/931089:CDES_RS00555 ^@ http://purl.uniprot.org/uniprot/A0A0M4CVD5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS09915 ^@ http://purl.uniprot.org/uniprot/A0A0M4CH50 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/931089:CDES_RS04775 ^@ http://purl.uniprot.org/uniprot/A0A0M5IU38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/931089:CDES_RS05775 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXI1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/931089:CDES_RS12935 ^@ http://purl.uniprot.org/uniprot/A0A0M4CS08 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS04455 ^@ http://purl.uniprot.org/uniprot/A0A0M4CD58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS05415 ^@ http://purl.uniprot.org/uniprot/A0A0M5IIH8 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/931089:CDES_RS08705 ^@ http://purl.uniprot.org/uniprot/A0A0M4CXX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/931089:CDES_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMN6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/931089:CDES_RS10530 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKN9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/931089:CDES_RS10665 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS11690 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHS6 ^@ Similarity ^@ Belongs to the PheA/TfdB FAD monooxygenase family. http://togogenome.org/gene/931089:CDES_RS09350 ^@ http://purl.uniprot.org/uniprot/A0A0M4CEL2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/931089:CDES_RS02885 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q956 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/931089:CDES_RS00300 ^@ http://purl.uniprot.org/uniprot/A0A0M5IFK1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS11540 ^@ http://purl.uniprot.org/uniprot/A0A0M4CND9 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/931089:CDES_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A0M4CDZ2 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/931089:CDES_RS04720 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHN2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/931089:CDES_RS07765 ^@ http://purl.uniprot.org/uniprot/A0A0M4CIN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/931089:CDES_RS03310 ^@ http://purl.uniprot.org/uniprot/A0A0M4CES3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/931089:CDES_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A0M4CKE2 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/931089:CDES_RS04275 ^@ http://purl.uniprot.org/uniprot/A0A0M4CNZ5 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/931089:CDES_RS03845 ^@ http://purl.uniprot.org/uniprot/A0A0M3Q994 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/931089:CDES_RS08595 ^@ http://purl.uniprot.org/uniprot/A0A0M4CED8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS06815 ^@ http://purl.uniprot.org/uniprot/A0A0M4CPZ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/931089:CDES_RS09670 ^@ http://purl.uniprot.org/uniprot/A0A0M4CMR8 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/931089:CDES_RS00250 ^@ http://purl.uniprot.org/uniprot/A0A0M4CHA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/931089:CDES_RS10115 ^@ http://purl.uniprot.org/uniprot/A0A0M5IUD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane