http://togogenome.org/gene/981222:CABTHER_RS05865 ^@ http://purl.uniprot.org/uniprot/G2LD87 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/981222:CABTHER_RS07725 ^@ http://purl.uniprot.org/uniprot/G2LIV2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer.|||In the N-terminal section; belongs to the DHBP synthase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS01645 ^@ http://purl.uniprot.org/uniprot/G2LE35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/981222:CABTHER_RS11100 ^@ http://purl.uniprot.org/uniprot/G2LF75 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/981222:CABTHER_RS11680 ^@ http://purl.uniprot.org/uniprot/G2LJV1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS11260 ^@ http://purl.uniprot.org/uniprot/G2LJL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/981222:CABTHER_RS14560 ^@ http://purl.uniprot.org/uniprot/G2LL26 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M15D family.|||Binds 1 zinc ion per subunit.|||Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. http://togogenome.org/gene/981222:CABTHER_RS03000 ^@ http://purl.uniprot.org/uniprot/G2LFG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS12340 ^@ http://purl.uniprot.org/uniprot/G2LKG5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS12245 ^@ http://purl.uniprot.org/uniprot/G2LKE6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS09750 ^@ http://purl.uniprot.org/uniprot/G2LIW7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS04255 ^@ http://purl.uniprot.org/uniprot/G2LEF6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS04905 ^@ http://purl.uniprot.org/uniprot/G2LFV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS06170 ^@ http://purl.uniprot.org/uniprot/G2LEM6 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/981222:CABTHER_RS05570 ^@ http://purl.uniprot.org/uniprot/G2LII8 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/981222:CABTHER_RS08170 ^@ http://purl.uniprot.org/uniprot/G2LDF3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS03980 ^@ http://purl.uniprot.org/uniprot/G2LIA6 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/981222:CABTHER_RS13920 ^@ http://purl.uniprot.org/uniprot/G2LK87 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/981222:CABTHER_RS10935 ^@ http://purl.uniprot.org/uniprot/G2LF40 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/981222:CABTHER_RS00840 ^@ http://purl.uniprot.org/uniprot/G2LGI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRISPR system Cmr5 family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS08750 ^@ http://purl.uniprot.org/uniprot/G2LEZ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/981222:CABTHER_RS07735 ^@ http://purl.uniprot.org/uniprot/G2LIV4 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/981222:CABTHER_RS06990 ^@ http://purl.uniprot.org/uniprot/G2LHA9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS07615 ^@ http://purl.uniprot.org/uniprot/G2LIT0 ^@ Caution|||Function|||Similarity ^@ Belongs to the RecR family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/981222:CABTHER_RS10570 ^@ http://purl.uniprot.org/uniprot/G2LDN7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS03025 ^@ http://purl.uniprot.org/uniprot/G2LFG5 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/981222:CABTHER_RS03215 ^@ http://purl.uniprot.org/uniprot/G2LFK4 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS01015 ^@ http://purl.uniprot.org/uniprot/G2LHR9 ^@ Similarity ^@ Belongs to the Lgt family. http://togogenome.org/gene/981222:CABTHER_RS04935 ^@ http://purl.uniprot.org/uniprot/G2LFW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS07375 ^@ http://purl.uniprot.org/uniprot/G2LIN1 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/981222:CABTHER_RS01540 ^@ http://purl.uniprot.org/uniprot/G2LE15 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/981222:CABTHER_RS11505 ^@ http://purl.uniprot.org/uniprot/G2LJR5 ^@ Similarity ^@ Belongs to the Mg-chelatase subunit H family. http://togogenome.org/gene/981222:CABTHER_RS04765 ^@ http://purl.uniprot.org/uniprot/G2LFS9 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/981222:CABTHER_RS01465 ^@ http://purl.uniprot.org/uniprot/G2LE01 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/981222:CABTHER_RS13265 ^@ http://purl.uniprot.org/uniprot/G2LLG5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer and homodimer. http://togogenome.org/gene/981222:CABTHER_RS04915 ^@ http://purl.uniprot.org/uniprot/G2LFW0 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/981222:CABTHER_RS00110 ^@ http://purl.uniprot.org/uniprot/G2LDX3 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/981222:CABTHER_RS07860 ^@ http://purl.uniprot.org/uniprot/G2LJ62 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/981222:CABTHER_RS02755 ^@ http://purl.uniprot.org/uniprot/G2LE92 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/981222:CABTHER_RS00515 ^@ http://purl.uniprot.org/uniprot/G2LFE6 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/981222:CABTHER_RS07955 ^@ http://purl.uniprot.org/uniprot/G2LJ82 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/981222:CABTHER_RS00700 ^@ http://purl.uniprot.org/uniprot/G2LGF6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS11405 ^@ http://purl.uniprot.org/uniprot/G2LJP5 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/981222:CABTHER_RS06805 ^@ http://purl.uniprot.org/uniprot/G2LG22 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/981222:CABTHER_RS03085 ^@ http://purl.uniprot.org/uniprot/G2LFH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/981222:CABTHER_RS06070 ^@ http://purl.uniprot.org/uniprot/G2LDD0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS11385 ^@ http://purl.uniprot.org/uniprot/G2LJP2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 27 family. http://togogenome.org/gene/981222:CABTHER_RS09220 ^@ http://purl.uniprot.org/uniprot/G2LGB3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/981222:CABTHER_RS13720 ^@ http://purl.uniprot.org/uniprot/G2LK47 ^@ Similarity ^@ Belongs to the FliN/MopA/SpaO family. http://togogenome.org/gene/981222:CABTHER_RS04225 ^@ http://purl.uniprot.org/uniprot/G2LEF0 ^@ Function ^@ Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. http://togogenome.org/gene/981222:CABTHER_RS02030 ^@ http://purl.uniprot.org/uniprot/G2LGQ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS04330 ^@ http://purl.uniprot.org/uniprot/G2LEH1 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/981222:CABTHER_RS09870 ^@ http://purl.uniprot.org/uniprot/G2LIZ1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/981222:CABTHER_RS03150 ^@ http://purl.uniprot.org/uniprot/G2LFI9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/981222:CABTHER_RS10380 ^@ http://purl.uniprot.org/uniprot/G2LJH2 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/981222:CABTHER_RS03145 ^@ http://purl.uniprot.org/uniprot/G2LFI8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/981222:CABTHER_RS12235 ^@ http://purl.uniprot.org/uniprot/G2LKE4 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS01675 ^@ http://purl.uniprot.org/uniprot/G2LE40 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/981222:CABTHER_RS11055 ^@ http://purl.uniprot.org/uniprot/G2LF65 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/981222:CABTHER_RS08115 ^@ http://purl.uniprot.org/uniprot/G2LJB3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS10170 ^@ http://purl.uniprot.org/uniprot/G2LJD0 ^@ Function|||Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.|||Catalyzes the biosynthesis of agmatine from arginine. http://togogenome.org/gene/981222:CABTHER_RS10740 ^@ http://purl.uniprot.org/uniprot/G2LDS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/981222:CABTHER_RS01715 ^@ http://purl.uniprot.org/uniprot/G2LE47 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS03140 ^@ http://purl.uniprot.org/uniprot/G2LFI7 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS04720 ^@ http://purl.uniprot.org/uniprot/G2LFS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/981222:CABTHER_RS09070 ^@ http://purl.uniprot.org/uniprot/G2LG83 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/981222:CABTHER_RS10950 ^@ http://purl.uniprot.org/uniprot/G2LF42 ^@ Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. http://togogenome.org/gene/981222:CABTHER_RS12525 ^@ http://purl.uniprot.org/uniprot/G2LKT4 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/981222:CABTHER_RS14855 ^@ http://purl.uniprot.org/uniprot/G2LL92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS15045 ^@ http://purl.uniprot.org/uniprot/G2LLL0 ^@ Function ^@ Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/981222:CABTHER_RS01995 ^@ http://purl.uniprot.org/uniprot/G2LGQ2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/981222:CABTHER_RS08640 ^@ http://purl.uniprot.org/uniprot/G2LEX5 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/981222:CABTHER_RS07985 ^@ http://purl.uniprot.org/uniprot/G2LJ89 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/981222:CABTHER_RS07610 ^@ http://purl.uniprot.org/uniprot/G2LIS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMO family.|||Endoplasmic reticulum membrane|||Membrane|||Microsome membrane http://togogenome.org/gene/981222:CABTHER_RS10085 ^@ http://purl.uniprot.org/uniprot/G2LJ34 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/981222:CABTHER_RS05670 ^@ http://purl.uniprot.org/uniprot/G2LIK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/981222:CABTHER_RS00365 ^@ http://purl.uniprot.org/uniprot/G2LFC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS14070 ^@ http://purl.uniprot.org/uniprot/G2LKB8 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/981222:CABTHER_RS07895 ^@ http://purl.uniprot.org/uniprot/G2LJ69 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/981222:CABTHER_RS10300 ^@ http://purl.uniprot.org/uniprot/G2LJF6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS01740 ^@ http://purl.uniprot.org/uniprot/G2LE51 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/981222:CABTHER_RS12705 ^@ http://purl.uniprot.org/uniprot/G2LKX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||In the C-terminal section; belongs to the OsmX family.|||In the N-terminal section; belongs to the binding-protein-dependent transport system permease family. http://togogenome.org/gene/981222:CABTHER_RS13585 ^@ http://purl.uniprot.org/uniprot/G2LLU1 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/981222:CABTHER_RS06590 ^@ http://purl.uniprot.org/uniprot/G2LFX9 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/981222:CABTHER_RS10425 ^@ http://purl.uniprot.org/uniprot/G2LJH9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS00790 ^@ http://purl.uniprot.org/uniprot/G2LGH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS08595 ^@ http://purl.uniprot.org/uniprot/G2LEW6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.|||This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. http://togogenome.org/gene/981222:CABTHER_RS09690 ^@ http://purl.uniprot.org/uniprot/G2LHQ8 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/981222:CABTHER_RS00735 ^@ http://purl.uniprot.org/uniprot/G2LGG3 ^@ Similarity ^@ Belongs to the geranylgeranyl reductase family. ChlP subfamily. http://togogenome.org/gene/981222:CABTHER_RS06215 ^@ http://purl.uniprot.org/uniprot/G2LEN6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/981222:CABTHER_RS06680 ^@ http://purl.uniprot.org/uniprot/G2LFZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/981222:CABTHER_RS04970 ^@ http://purl.uniprot.org/uniprot/G2LH22 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS08270 ^@ http://purl.uniprot.org/uniprot/G2LDH3 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/981222:CABTHER_RS12815 ^@ http://purl.uniprot.org/uniprot/G2LKZ2 ^@ Function ^@ CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/981222:CABTHER_RS10295 ^@ http://purl.uniprot.org/uniprot/G2LJF5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS00290 ^@ http://purl.uniprot.org/uniprot/G2LFA7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS13525 ^@ http://purl.uniprot.org/uniprot/G2LLS8 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/981222:CABTHER_RS01895 ^@ http://purl.uniprot.org/uniprot/G2LGN1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS09335 ^@ http://purl.uniprot.org/uniprot/G2LHI5 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/981222:CABTHER_RS14065 ^@ http://purl.uniprot.org/uniprot/G2LKB7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS12655 ^@ http://purl.uniprot.org/uniprot/G2LKW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS11780 ^@ http://purl.uniprot.org/uniprot/G2LJX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the kinesin light chain family.|||cytoskeleton http://togogenome.org/gene/981222:CABTHER_RS08615 ^@ http://purl.uniprot.org/uniprot/G2LEX0 ^@ Function|||Similarity ^@ Belongs to the peptidase S46 family.|||Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. http://togogenome.org/gene/981222:CABTHER_RS06035 ^@ http://purl.uniprot.org/uniprot/G2LDC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/981222:CABTHER_RS07045 ^@ http://purl.uniprot.org/uniprot/G2LHC1 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/981222:CABTHER_RS09965 ^@ http://purl.uniprot.org/uniprot/G2LJ10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 5 family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS10970 ^@ http://purl.uniprot.org/uniprot/G2LF46 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/981222:CABTHER_RS12335 ^@ http://purl.uniprot.org/uniprot/G2LKG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS15995 ^@ http://purl.uniprot.org/uniprot/G2LDQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RecU family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS11950 ^@ http://purl.uniprot.org/uniprot/G2LK05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/981222:CABTHER_RS14905 ^@ http://purl.uniprot.org/uniprot/G2LLI2 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/981222:CABTHER_RS05065 ^@ http://purl.uniprot.org/uniprot/G2LH42 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS11280 ^@ http://purl.uniprot.org/uniprot/G2LJM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS05790 ^@ http://purl.uniprot.org/uniprot/G2LD71 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/981222:CABTHER_RS07035 ^@ http://purl.uniprot.org/uniprot/G2LHB8 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/981222:CABTHER_RS09845 ^@ http://purl.uniprot.org/uniprot/G2LIY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/981222:CABTHER_RS01825 ^@ http://purl.uniprot.org/uniprot/G2LGL8 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/981222:CABTHER_RS15370 ^@ http://purl.uniprot.org/uniprot/G2LEC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS14510 ^@ http://purl.uniprot.org/uniprot/G2LL15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS09100 ^@ http://purl.uniprot.org/uniprot/G2LG89 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/981222:CABTHER_RS13085 ^@ http://purl.uniprot.org/uniprot/G2LLC8 ^@ Similarity ^@ Belongs to the UPF0166 family. http://togogenome.org/gene/981222:CABTHER_RS02085 ^@ http://purl.uniprot.org/uniprot/G2LGS0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS08065 ^@ http://purl.uniprot.org/uniprot/G2LJA4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/981222:CABTHER_RS14960 ^@ http://purl.uniprot.org/uniprot/G2LLJ3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS10620 ^@ http://purl.uniprot.org/uniprot/G2LDP8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/981222:CABTHER_RS00960 ^@ http://purl.uniprot.org/uniprot/G2LGK8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/981222:CABTHER_RS10900 ^@ http://purl.uniprot.org/uniprot/G2LF33 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/981222:CABTHER_RS05545 ^@ http://purl.uniprot.org/uniprot/G2LII3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/981222:CABTHER_RS09725 ^@ http://purl.uniprot.org/uniprot/G2LIW2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/981222:CABTHER_RS03210 ^@ http://purl.uniprot.org/uniprot/G2LFK3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/981222:CABTHER_RS13340 ^@ http://purl.uniprot.org/uniprot/G2LLP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS01945 ^@ http://purl.uniprot.org/uniprot/G2LGP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS04565 ^@ http://purl.uniprot.org/uniprot/G2LEL8 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/981222:CABTHER_RS01190 ^@ http://purl.uniprot.org/uniprot/G2LHU8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/981222:CABTHER_RS02935 ^@ http://purl.uniprot.org/uniprot/G2LEC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/981222:CABTHER_RS00625 ^@ http://purl.uniprot.org/uniprot/G2LGE1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/981222:CABTHER_RS09675 ^@ http://purl.uniprot.org/uniprot/G2LHQ5 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/981222:CABTHER_RS05730 ^@ http://purl.uniprot.org/uniprot/G2LIM0 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/981222:CABTHER_RS14095 ^@ http://purl.uniprot.org/uniprot/G2LKK3 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/981222:CABTHER_RS11765 ^@ http://purl.uniprot.org/uniprot/G2LJW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the kinesin light chain family.|||cytoskeleton http://togogenome.org/gene/981222:CABTHER_RS02810 ^@ http://purl.uniprot.org/uniprot/G2LEA4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/981222:CABTHER_RS12895 ^@ http://purl.uniprot.org/uniprot/G2LL08 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS01605 ^@ http://purl.uniprot.org/uniprot/G2LE28 ^@ Similarity|||Subunit ^@ Belongs to the FPG family.|||Monomer. http://togogenome.org/gene/981222:CABTHER_RS09135 ^@ http://purl.uniprot.org/uniprot/G2LG96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS14515 ^@ http://purl.uniprot.org/uniprot/G2LL16 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS04630 ^@ http://purl.uniprot.org/uniprot/G2LFQ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS09975 ^@ http://purl.uniprot.org/uniprot/G2LJ12 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/981222:CABTHER_RS10490 ^@ http://purl.uniprot.org/uniprot/G2LJI9 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/981222:CABTHER_RS00985 ^@ http://purl.uniprot.org/uniprot/G2LHR3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/981222:CABTHER_RS08735 ^@ http://purl.uniprot.org/uniprot/G2LEZ4 ^@ Similarity ^@ Belongs to the homogentisate dioxygenase family. http://togogenome.org/gene/981222:CABTHER_RS09655 ^@ http://purl.uniprot.org/uniprot/G2LHQ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS05665 ^@ http://purl.uniprot.org/uniprot/G2LIK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/981222:CABTHER_RS11945 ^@ http://purl.uniprot.org/uniprot/G2LK04 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/981222:CABTHER_RS04480 ^@ http://purl.uniprot.org/uniprot/G2LEK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS10925 ^@ http://purl.uniprot.org/uniprot/G2LF38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/981222:CABTHER_RS16045 ^@ http://purl.uniprot.org/uniprot/G2LF43 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/981222:CABTHER_RS09515 ^@ http://purl.uniprot.org/uniprot/G2LHM4 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/981222:CABTHER_RS01360 ^@ http://purl.uniprot.org/uniprot/G2LHY2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/981222:CABTHER_RS09205 ^@ http://purl.uniprot.org/uniprot/G2LGB0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/981222:CABTHER_RS07135 ^@ http://purl.uniprot.org/uniprot/G2LHD8 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/981222:CABTHER_RS01625 ^@ http://purl.uniprot.org/uniprot/G2LE31 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS12635 ^@ http://purl.uniprot.org/uniprot/G2LKV6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS05820 ^@ http://purl.uniprot.org/uniprot/G2LD78 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/981222:CABTHER_RS12480 ^@ http://purl.uniprot.org/uniprot/G2LKJ4 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/981222:CABTHER_RS05845 ^@ http://purl.uniprot.org/uniprot/G2LD83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS02215 ^@ http://purl.uniprot.org/uniprot/G2LHZ1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/981222:CABTHER_RS10600 ^@ http://purl.uniprot.org/uniprot/G2LDP3 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS10445 ^@ http://purl.uniprot.org/uniprot/G2LJI3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/981222:CABTHER_RS05145 ^@ http://purl.uniprot.org/uniprot/G2LH58 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/981222:CABTHER_RS02425 ^@ http://purl.uniprot.org/uniprot/G2LI34 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. PCD1 subfamily. http://togogenome.org/gene/981222:CABTHER_RS08520 ^@ http://purl.uniprot.org/uniprot/G2LEV1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/981222:CABTHER_RS01695 ^@ http://purl.uniprot.org/uniprot/G2LE43 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS02950 ^@ http://purl.uniprot.org/uniprot/G2LED2 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/981222:CABTHER_RS02020 ^@ http://purl.uniprot.org/uniprot/G2LGQ7 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/981222:CABTHER_RS12295 ^@ http://purl.uniprot.org/uniprot/G2LKF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS15855 ^@ http://purl.uniprot.org/uniprot/G2LF03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS07460 ^@ http://purl.uniprot.org/uniprot/G2LIP8 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/981222:CABTHER_RS00445 ^@ http://purl.uniprot.org/uniprot/G2LFD3 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/981222:CABTHER_RS07340 ^@ http://purl.uniprot.org/uniprot/G2LHH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/981222:CABTHER_RS04610 ^@ http://purl.uniprot.org/uniprot/G2LFP7 ^@ Similarity ^@ Belongs to the NifH/BchL/ChlL family. http://togogenome.org/gene/981222:CABTHER_RS12075 ^@ http://purl.uniprot.org/uniprot/G2LK31 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the selenophosphate synthase 1 family. Class I subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Homodimer.|||Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/981222:CABTHER_RS06380 ^@ http://purl.uniprot.org/uniprot/G2LER8 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/981222:CABTHER_RS03520 ^@ http://purl.uniprot.org/uniprot/G2LGW8 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/981222:CABTHER_RS11355 ^@ http://purl.uniprot.org/uniprot/G2LJN6 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS11645 ^@ http://purl.uniprot.org/uniprot/G2LJU3 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/981222:CABTHER_RS12175 ^@ http://purl.uniprot.org/uniprot/G2LKD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS04080 ^@ http://purl.uniprot.org/uniprot/G2LIC6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/981222:CABTHER_RS10390 ^@ http://purl.uniprot.org/uniprot/G2LJH4 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/981222:CABTHER_RS06870 ^@ http://purl.uniprot.org/uniprot/G2LG35 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 3-HAO family.|||Binds 2 Fe(2+) ions per subunit.|||Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. http://togogenome.org/gene/981222:CABTHER_RS07845 ^@ http://purl.uniprot.org/uniprot/G2LJ59 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/981222:CABTHER_RS01595 ^@ http://purl.uniprot.org/uniprot/G2LE26 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/981222:CABTHER_RS07125 ^@ http://purl.uniprot.org/uniprot/G2LHD6 ^@ Similarity ^@ Belongs to the DAMOX/DASOX family. http://togogenome.org/gene/981222:CABTHER_RS10770 ^@ http://purl.uniprot.org/uniprot/G2LDS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS11545 ^@ http://purl.uniprot.org/uniprot/G2LJS3 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/981222:CABTHER_RS07400 ^@ http://purl.uniprot.org/uniprot/G2LIN6 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/981222:CABTHER_RS02585 ^@ http://purl.uniprot.org/uniprot/G2LE59 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/981222:CABTHER_RS07015 ^@ http://purl.uniprot.org/uniprot/G2LHB4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS03680 ^@ http://purl.uniprot.org/uniprot/G2LH00 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/981222:CABTHER_RS06355 ^@ http://purl.uniprot.org/uniprot/G2LER3 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family.|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS03320 ^@ http://purl.uniprot.org/uniprot/G2LFM5 ^@ Cofactor|||Similarity ^@ Belongs to the arginase family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/981222:CABTHER_RS08700 ^@ http://purl.uniprot.org/uniprot/G2LEY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS00715 ^@ http://purl.uniprot.org/uniprot/G2LGF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS02280 ^@ http://purl.uniprot.org/uniprot/G2LI04 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/981222:CABTHER_RS05860 ^@ http://purl.uniprot.org/uniprot/G2LD86 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS08255 ^@ http://purl.uniprot.org/uniprot/G2LDH0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/981222:CABTHER_RS08045 ^@ http://purl.uniprot.org/uniprot/G2LJA0 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/981222:CABTHER_RS09660 ^@ http://purl.uniprot.org/uniprot/G2LHQ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS04105 ^@ http://purl.uniprot.org/uniprot/G2LID1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS00370 ^@ http://purl.uniprot.org/uniprot/G2LFC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS01160 ^@ http://purl.uniprot.org/uniprot/G2LHU2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/981222:CABTHER_RS05395 ^@ http://purl.uniprot.org/uniprot/G2LIF1 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/981222:CABTHER_RS11240 ^@ http://purl.uniprot.org/uniprot/G2LJL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SctL stator family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS00135 ^@ http://purl.uniprot.org/uniprot/G2LDX8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS01265 ^@ http://purl.uniprot.org/uniprot/G2LHW3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/981222:CABTHER_RS08110 ^@ http://purl.uniprot.org/uniprot/G2LJB2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS06815 ^@ http://purl.uniprot.org/uniprot/G2LG24 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/981222:CABTHER_RS10165 ^@ http://purl.uniprot.org/uniprot/G2LJC9 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/981222:CABTHER_RS14400 ^@ http://purl.uniprot.org/uniprot/G2LKR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the kinesin light chain family.|||cytoskeleton http://togogenome.org/gene/981222:CABTHER_RS10930 ^@ http://purl.uniprot.org/uniprot/G2LF39 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/981222:CABTHER_RS09555 ^@ http://purl.uniprot.org/uniprot/G2LHN1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS03155 ^@ http://purl.uniprot.org/uniprot/G2LFJ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/981222:CABTHER_RS04045 ^@ http://purl.uniprot.org/uniprot/G2LIB9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/981222:CABTHER_RS02805 ^@ http://purl.uniprot.org/uniprot/G2LEA3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/981222:CABTHER_RS12910 ^@ http://purl.uniprot.org/uniprot/G2LL11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS00235 ^@ http://purl.uniprot.org/uniprot/G2LF96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRISPR system Cmr5 family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS12030 ^@ http://purl.uniprot.org/uniprot/G2LK21 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/981222:CABTHER_RS03305 ^@ http://purl.uniprot.org/uniprot/G2LFM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/981222:CABTHER_RS08920 ^@ http://purl.uniprot.org/uniprot/G2LG52 ^@ Similarity ^@ Belongs to the HY2 family. http://togogenome.org/gene/981222:CABTHER_RS06850 ^@ http://purl.uniprot.org/uniprot/G2LG31 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/981222:CABTHER_RS14500 ^@ http://purl.uniprot.org/uniprot/G2LKT2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS04315 ^@ http://purl.uniprot.org/uniprot/G2LEG8 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/981222:CABTHER_RS10010 ^@ http://purl.uniprot.org/uniprot/G2LJ18 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/981222:CABTHER_RS10850 ^@ http://purl.uniprot.org/uniprot/G2LDU4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS07335 ^@ http://purl.uniprot.org/uniprot/G2LHH8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/981222:CABTHER_RS11075 ^@ http://purl.uniprot.org/uniprot/G2LF69 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/981222:CABTHER_RS10470 ^@ http://purl.uniprot.org/uniprot/G2LJI6 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/981222:CABTHER_RS15635 ^@ http://purl.uniprot.org/uniprot/G2LII6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS11895 ^@ http://purl.uniprot.org/uniprot/G2LJZ4 ^@ Similarity ^@ Belongs to the MscS (TC 1.A.23) family. http://togogenome.org/gene/981222:CABTHER_RS00810 ^@ http://purl.uniprot.org/uniprot/G2LGH8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS16065 ^@ http://purl.uniprot.org/uniprot/G2LJJ3 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/981222:CABTHER_RS06240 ^@ http://purl.uniprot.org/uniprot/G2LEP1 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/981222:CABTHER_RS11750 ^@ http://purl.uniprot.org/uniprot/G2LJW5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS14915 ^@ http://purl.uniprot.org/uniprot/G2LLI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS06635 ^@ http://purl.uniprot.org/uniprot/G2LFY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS03205 ^@ http://purl.uniprot.org/uniprot/G2LFK2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS02865 ^@ http://purl.uniprot.org/uniprot/G2LEB5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS12955 ^@ http://purl.uniprot.org/uniprot/G2LLA1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/981222:CABTHER_RS00900 ^@ http://purl.uniprot.org/uniprot/G2LGJ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS07210 ^@ http://purl.uniprot.org/uniprot/G2LHF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS09280 ^@ http://purl.uniprot.org/uniprot/G2LGC5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS04820 ^@ http://purl.uniprot.org/uniprot/G2LFU1 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/981222:CABTHER_RS03535 ^@ http://purl.uniprot.org/uniprot/G2LGX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS09800 ^@ http://purl.uniprot.org/uniprot/G2LIX7 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/981222:CABTHER_RS12185 ^@ http://purl.uniprot.org/uniprot/G2LKD4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS11660 ^@ http://purl.uniprot.org/uniprot/G2LJU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS08560 ^@ http://purl.uniprot.org/uniprot/G2LEV9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/981222:CABTHER_RS06200 ^@ http://purl.uniprot.org/uniprot/G2LEN2 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS05930 ^@ http://purl.uniprot.org/uniprot/G2LDA0 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/981222:CABTHER_RS08835 ^@ http://purl.uniprot.org/uniprot/G2LF15 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/981222:CABTHER_RS09760 ^@ http://purl.uniprot.org/uniprot/G2LIW9 ^@ Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/981222:CABTHER_RS03540 ^@ http://purl.uniprot.org/uniprot/G2LGX3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/981222:CABTHER_RS02385 ^@ http://purl.uniprot.org/uniprot/G2LI25 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/981222:CABTHER_RS05515 ^@ http://purl.uniprot.org/uniprot/G2LIH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/981222:CABTHER_RS00635 ^@ http://purl.uniprot.org/uniprot/G2LGE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS04205 ^@ http://purl.uniprot.org/uniprot/G2LEE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS03555 ^@ http://purl.uniprot.org/uniprot/G2LGX5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/981222:CABTHER_RS01565 ^@ http://purl.uniprot.org/uniprot/G2LE20 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/981222:CABTHER_RS10195 ^@ http://purl.uniprot.org/uniprot/G2LJD5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/981222:CABTHER_RS08335 ^@ http://purl.uniprot.org/uniprot/G2LDI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS03250 ^@ http://purl.uniprot.org/uniprot/G2LFL1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the MsrP family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide. http://togogenome.org/gene/981222:CABTHER_RS14020 ^@ http://purl.uniprot.org/uniprot/G2LKA8 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS08175 ^@ http://purl.uniprot.org/uniprot/G2LDF4 ^@ Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family. http://togogenome.org/gene/981222:CABTHER_RS05685 ^@ http://purl.uniprot.org/uniprot/G2LIL1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS05115 ^@ http://purl.uniprot.org/uniprot/G2LH52 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS11265 ^@ http://purl.uniprot.org/uniprot/G2LJL7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/981222:CABTHER_RS10625 ^@ http://purl.uniprot.org/uniprot/G2LDP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS08545 ^@ http://purl.uniprot.org/uniprot/G2LEV6 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/981222:CABTHER_RS01075 ^@ http://purl.uniprot.org/uniprot/G2LHT0 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/981222:CABTHER_RS06360 ^@ http://purl.uniprot.org/uniprot/G2LER4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/981222:CABTHER_RS09035 ^@ http://purl.uniprot.org/uniprot/G2LG75 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/981222:CABTHER_RS09355 ^@ http://purl.uniprot.org/uniprot/G2LHI9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS14430 ^@ http://purl.uniprot.org/uniprot/G2LKR8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 63 family. http://togogenome.org/gene/981222:CABTHER_RS11480 ^@ http://purl.uniprot.org/uniprot/G2LJR0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/981222:CABTHER_RS10585 ^@ http://purl.uniprot.org/uniprot/G2LDP0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/981222:CABTHER_RS01380 ^@ http://purl.uniprot.org/uniprot/G2LDY4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/981222:CABTHER_RS13195 ^@ http://purl.uniprot.org/uniprot/G2LLF1 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/981222:CABTHER_RS00105 ^@ http://purl.uniprot.org/uniprot/G2LDX2 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/981222:CABTHER_RS08275 ^@ http://purl.uniprot.org/uniprot/G2LDH4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/981222:CABTHER_RS03660 ^@ http://purl.uniprot.org/uniprot/G2LGZ6 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/981222:CABTHER_RS07990 ^@ http://purl.uniprot.org/uniprot/G2LJ90 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/981222:CABTHER_RS11425 ^@ http://purl.uniprot.org/uniprot/G2LJP9 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS01950 ^@ http://purl.uniprot.org/uniprot/G2LGP3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/981222:CABTHER_RS06660 ^@ http://purl.uniprot.org/uniprot/G2LFZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS00800 ^@ http://purl.uniprot.org/uniprot/G2LGH6 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/981222:CABTHER_RS13925 ^@ http://purl.uniprot.org/uniprot/G2LK88 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/981222:CABTHER_RS09665 ^@ http://purl.uniprot.org/uniprot/G2LHQ3 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/981222:CABTHER_RS01820 ^@ http://purl.uniprot.org/uniprot/G2LGL7 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/981222:CABTHER_RS04275 ^@ http://purl.uniprot.org/uniprot/G2LEG0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS08795 ^@ http://purl.uniprot.org/uniprot/G2LF07 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS13375 ^@ http://purl.uniprot.org/uniprot/G2LLP8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/981222:CABTHER_RS11205 ^@ http://purl.uniprot.org/uniprot/G2LJK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS14505 ^@ http://purl.uniprot.org/uniprot/G2LKT3 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/981222:CABTHER_RS08870 ^@ http://purl.uniprot.org/uniprot/G2LF22 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/981222:CABTHER_RS02380 ^@ http://purl.uniprot.org/uniprot/G2LI24 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/981222:CABTHER_RS16010 ^@ http://purl.uniprot.org/uniprot/G2LDS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS08485 ^@ http://purl.uniprot.org/uniprot/G2LDL5 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/981222:CABTHER_RS07395 ^@ http://purl.uniprot.org/uniprot/G2LIN5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS01575 ^@ http://purl.uniprot.org/uniprot/G2LE22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/981222:CABTHER_RS07260 ^@ http://purl.uniprot.org/uniprot/G2LHG3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/981222:CABTHER_RS00520 ^@ http://purl.uniprot.org/uniprot/G2LFE7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS09365 ^@ http://purl.uniprot.org/uniprot/G2LHJ1 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/981222:CABTHER_RS01710 ^@ http://purl.uniprot.org/uniprot/G2LE46 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/981222:CABTHER_RS02600 ^@ http://purl.uniprot.org/uniprot/G2LE62 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/981222:CABTHER_RS00115 ^@ http://purl.uniprot.org/uniprot/G2LDX4 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/981222:CABTHER_RS06385 ^@ http://purl.uniprot.org/uniprot/G2LER9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS03840 ^@ http://purl.uniprot.org/uniprot/G2LI78 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/981222:CABTHER_RS06465 ^@ http://purl.uniprot.org/uniprot/G2LET4 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/981222:CABTHER_RS01630 ^@ http://purl.uniprot.org/uniprot/G2LE32 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/981222:CABTHER_RS08325 ^@ http://purl.uniprot.org/uniprot/G2LDI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP E family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS00705 ^@ http://purl.uniprot.org/uniprot/G2LGF7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS00015 ^@ http://purl.uniprot.org/uniprot/G2LDV2 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/981222:CABTHER_RS11760 ^@ http://purl.uniprot.org/uniprot/G2LJW7 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/981222:CABTHER_RS01530 ^@ http://purl.uniprot.org/uniprot/G2LE13 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/981222:CABTHER_RS08505 ^@ http://purl.uniprot.org/uniprot/G2LDM1 ^@ Similarity ^@ Belongs to the glycosyltransferase 2 family. http://togogenome.org/gene/981222:CABTHER_RS13285 ^@ http://purl.uniprot.org/uniprot/G2LLG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS04415 ^@ http://purl.uniprot.org/uniprot/G2LEI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS11030 ^@ http://purl.uniprot.org/uniprot/G2LF58 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/981222:CABTHER_RS11605 ^@ http://purl.uniprot.org/uniprot/G2LJT6 ^@ Similarity ^@ Belongs to the CbbQ/NirQ/NorQ/GpvN family. http://togogenome.org/gene/981222:CABTHER_RS05435 ^@ http://purl.uniprot.org/uniprot/G2LIF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS04130 ^@ http://purl.uniprot.org/uniprot/G2LID6 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/981222:CABTHER_RS10285 ^@ http://purl.uniprot.org/uniprot/G2LJF3 ^@ Function|||Similarity ^@ Belongs to the aromatic-ring hydroxylase family. KMO subfamily.|||Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. http://togogenome.org/gene/981222:CABTHER_RS11725 ^@ http://purl.uniprot.org/uniprot/G2LJW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS03310 ^@ http://purl.uniprot.org/uniprot/G2LFM3 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family. http://togogenome.org/gene/981222:CABTHER_RS01150 ^@ http://purl.uniprot.org/uniprot/G2LHH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/981222:CABTHER_RS11380 ^@ http://purl.uniprot.org/uniprot/G2LJP1 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/981222:CABTHER_RS06095 ^@ http://purl.uniprot.org/uniprot/G2LDD5 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/981222:CABTHER_RS09950 ^@ http://purl.uniprot.org/uniprot/G2LJ07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/981222:CABTHER_RS05905 ^@ http://purl.uniprot.org/uniprot/G2LD95 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/981222:CABTHER_RS08690 ^@ http://purl.uniprot.org/uniprot/G2LEY5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS02840 ^@ http://purl.uniprot.org/uniprot/G2LEB0 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/981222:CABTHER_RS02675 ^@ http://purl.uniprot.org/uniprot/G2LE75 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/981222:CABTHER_RS01555 ^@ http://purl.uniprot.org/uniprot/G2LE18 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS05440 ^@ http://purl.uniprot.org/uniprot/G2LIG0 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS00100 ^@ http://purl.uniprot.org/uniprot/G2LDX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/981222:CABTHER_RS11455 ^@ http://purl.uniprot.org/uniprot/G2LJQ5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/981222:CABTHER_RS02990 ^@ http://purl.uniprot.org/uniprot/G2LFF8 ^@ Function|||Similarity ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane. http://togogenome.org/gene/981222:CABTHER_RS12145 ^@ http://purl.uniprot.org/uniprot/G2LKC6 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS08650 ^@ http://purl.uniprot.org/uniprot/G2LEX7 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/981222:CABTHER_RS01065 ^@ http://purl.uniprot.org/uniprot/G2LHS8 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/981222:CABTHER_RS06430 ^@ http://purl.uniprot.org/uniprot/G2LES7 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/981222:CABTHER_RS00875 ^@ http://purl.uniprot.org/uniprot/G2LGJ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS01985 ^@ http://purl.uniprot.org/uniprot/G2LGQ0 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/981222:CABTHER_RS10965 ^@ http://purl.uniprot.org/uniprot/G2LF45 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/981222:CABTHER_RS02800 ^@ http://purl.uniprot.org/uniprot/G2LEA1 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/981222:CABTHER_RS07495 ^@ http://purl.uniprot.org/uniprot/G2LIQ6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/981222:CABTHER_RS01055 ^@ http://purl.uniprot.org/uniprot/G2LHS6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS08725 ^@ http://purl.uniprot.org/uniprot/G2LEZ2 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/981222:CABTHER_RS13660 ^@ http://purl.uniprot.org/uniprot/G2LLW0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/981222:CABTHER_RS06665 ^@ http://purl.uniprot.org/uniprot/G2LFZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 5 family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS14845 ^@ http://purl.uniprot.org/uniprot/G2LL90 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/981222:CABTHER_RS02505 ^@ http://purl.uniprot.org/uniprot/G2LI50 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. http://togogenome.org/gene/981222:CABTHER_RS09600 ^@ http://purl.uniprot.org/uniprot/G2LHP0 ^@ Similarity ^@ Belongs to the LarC family. http://togogenome.org/gene/981222:CABTHER_RS01980 ^@ http://purl.uniprot.org/uniprot/G2LGP9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS00820 ^@ http://purl.uniprot.org/uniprot/G2LGI0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/981222:CABTHER_RS07500 ^@ http://purl.uniprot.org/uniprot/G2LIQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS11320 ^@ http://purl.uniprot.org/uniprot/G2LJM8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS08035 ^@ http://purl.uniprot.org/uniprot/G2LJ98 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/981222:CABTHER_RS05160 ^@ http://purl.uniprot.org/uniprot/G2LH61 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS00165 ^@ http://purl.uniprot.org/uniprot/G2LF82 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/981222:CABTHER_RS05740 ^@ http://purl.uniprot.org/uniprot/G2LIM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS09890 ^@ http://purl.uniprot.org/uniprot/G2LIZ5 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/981222:CABTHER_RS01110 ^@ http://purl.uniprot.org/uniprot/G2LHT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS05555 ^@ http://purl.uniprot.org/uniprot/G2LII5 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/981222:CABTHER_RS02185 ^@ http://purl.uniprot.org/uniprot/G2LHY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/981222:CABTHER_RS07745 ^@ http://purl.uniprot.org/uniprot/G2LJ38 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS14925 ^@ http://purl.uniprot.org/uniprot/G2LLI6 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/981222:CABTHER_RS09860 ^@ http://purl.uniprot.org/uniprot/G2LIY9 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/981222:CABTHER_RS05785 ^@ http://purl.uniprot.org/uniprot/G2LD70 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/981222:CABTHER_RS14825 ^@ http://purl.uniprot.org/uniprot/G2LL86 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/981222:CABTHER_RS01335 ^@ http://purl.uniprot.org/uniprot/G2LHX6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS06190 ^@ http://purl.uniprot.org/uniprot/G2LEN0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS04975 ^@ http://purl.uniprot.org/uniprot/G2LH23 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/981222:CABTHER_RS04145 ^@ http://purl.uniprot.org/uniprot/G2LID9 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/981222:CABTHER_RS07620 ^@ http://purl.uniprot.org/uniprot/G2LIT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/981222:CABTHER_RS02465 ^@ http://purl.uniprot.org/uniprot/G2LI42 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/981222:CABTHER_RS00350 ^@ http://purl.uniprot.org/uniprot/G2LFB9 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/981222:CABTHER_RS04435 ^@ http://purl.uniprot.org/uniprot/G2LEJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS15985 ^@ http://purl.uniprot.org/uniprot/G2LJG7 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/981222:CABTHER_RS13390 ^@ http://purl.uniprot.org/uniprot/G2LLQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS04180 ^@ http://purl.uniprot.org/uniprot/G2LEE1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS10360 ^@ http://purl.uniprot.org/uniprot/G2LJG8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/981222:CABTHER_RS05960 ^@ http://purl.uniprot.org/uniprot/G2LDA6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/981222:CABTHER_RS00190 ^@ http://purl.uniprot.org/uniprot/G2LF87 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS12830 ^@ http://purl.uniprot.org/uniprot/G2LKZ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/981222:CABTHER_RS06980 ^@ http://purl.uniprot.org/uniprot/G2LHA7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/981222:CABTHER_RS14075 ^@ http://purl.uniprot.org/uniprot/G2LKB9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/981222:CABTHER_RS10905 ^@ http://purl.uniprot.org/uniprot/G2LF34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS14330 ^@ http://purl.uniprot.org/uniprot/G2LKP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS06300 ^@ http://purl.uniprot.org/uniprot/G2LEQ2 ^@ Similarity ^@ Belongs to the peptidase M28 family. M28B subfamily. http://togogenome.org/gene/981222:CABTHER_RS15400 ^@ http://purl.uniprot.org/uniprot/G2LFL6 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/981222:CABTHER_RS13130 ^@ http://purl.uniprot.org/uniprot/G2LLD7 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/981222:CABTHER_RS11065 ^@ http://purl.uniprot.org/uniprot/G2LF67 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS04420 ^@ http://purl.uniprot.org/uniprot/G2LEI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS09200 ^@ http://purl.uniprot.org/uniprot/G2LGA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/981222:CABTHER_RS03170 ^@ http://purl.uniprot.org/uniprot/G2LFJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/981222:CABTHER_RS10725 ^@ http://purl.uniprot.org/uniprot/G2LDR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/981222:CABTHER_RS10340 ^@ http://purl.uniprot.org/uniprot/G2LJG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS01020 ^@ http://purl.uniprot.org/uniprot/G2LHS0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/981222:CABTHER_RS04640 ^@ http://purl.uniprot.org/uniprot/G2LFQ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS13995 ^@ http://purl.uniprot.org/uniprot/G2LKA3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/981222:CABTHER_RS04260 ^@ http://purl.uniprot.org/uniprot/G2LEF7 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/981222:CABTHER_RS15805 ^@ http://purl.uniprot.org/uniprot/G2LJB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/981222:CABTHER_RS08535 ^@ http://purl.uniprot.org/uniprot/G2LEV4 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/981222:CABTHER_RS01920 ^@ http://purl.uniprot.org/uniprot/G2LGN7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS01915 ^@ http://purl.uniprot.org/uniprot/G2LGN6 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS05575 ^@ http://purl.uniprot.org/uniprot/G2LII9 ^@ Similarity ^@ Belongs to the peptidase C15 family. http://togogenome.org/gene/981222:CABTHER_RS03910 ^@ http://purl.uniprot.org/uniprot/G2LI92 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/981222:CABTHER_RS09765 ^@ http://purl.uniprot.org/uniprot/G2LIX0 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/981222:CABTHER_RS00300 ^@ http://purl.uniprot.org/uniprot/G2LFA9 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/981222:CABTHER_RS00505 ^@ http://purl.uniprot.org/uniprot/G2LFE4 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/981222:CABTHER_RS15330 ^@ http://purl.uniprot.org/uniprot/G2LI55 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS07980 ^@ http://purl.uniprot.org/uniprot/G2LJ88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/981222:CABTHER_RS08555 ^@ http://purl.uniprot.org/uniprot/G2LEV8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS04025 ^@ http://purl.uniprot.org/uniprot/G2LIB5 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/981222:CABTHER_RS03410 ^@ http://purl.uniprot.org/uniprot/G2LGU4 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/981222:CABTHER_RS00335 ^@ http://purl.uniprot.org/uniprot/G2LFB6 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/981222:CABTHER_RS09390 ^@ http://purl.uniprot.org/uniprot/G2LHJ6 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/981222:CABTHER_RS05085 ^@ http://purl.uniprot.org/uniprot/G2LH46 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/981222:CABTHER_RS02025 ^@ http://purl.uniprot.org/uniprot/G2LGQ8 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/981222:CABTHER_RS11430 ^@ http://purl.uniprot.org/uniprot/G2LJQ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS02730 ^@ http://purl.uniprot.org/uniprot/G2LE86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS04505 ^@ http://purl.uniprot.org/uniprot/G2LEK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS00995 ^@ http://purl.uniprot.org/uniprot/G2LHR5 ^@ Cofactor|||Similarity ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/981222:CABTHER_RS04695 ^@ http://purl.uniprot.org/uniprot/G2LFR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS10605 ^@ http://purl.uniprot.org/uniprot/G2LDP4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/981222:CABTHER_RS11915 ^@ http://purl.uniprot.org/uniprot/G2LJZ8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS03890 ^@ http://purl.uniprot.org/uniprot/G2LI88 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/981222:CABTHER_RS12935 ^@ http://purl.uniprot.org/uniprot/G2LL96 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/981222:CABTHER_RS06800 ^@ http://purl.uniprot.org/uniprot/G2LG21 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/981222:CABTHER_RS00455 ^@ http://purl.uniprot.org/uniprot/G2LFD5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/981222:CABTHER_RS03445 ^@ http://purl.uniprot.org/uniprot/G2LGV2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS08190 ^@ http://purl.uniprot.org/uniprot/G2LDF8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/981222:CABTHER_RS04410 ^@ http://purl.uniprot.org/uniprot/G2LEI7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/981222:CABTHER_RS07185 ^@ http://purl.uniprot.org/uniprot/G2LHE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS01910 ^@ http://purl.uniprot.org/uniprot/G2LGN5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/981222:CABTHER_RS10315 ^@ http://purl.uniprot.org/uniprot/G2LJF9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. C-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/981222:CABTHER_RS00620 ^@ http://purl.uniprot.org/uniprot/G2LGE0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/981222:CABTHER_RS16050 ^@ http://purl.uniprot.org/uniprot/G2LF56 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS13735 ^@ http://purl.uniprot.org/uniprot/G2LK50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/981222:CABTHER_RS03355 ^@ http://purl.uniprot.org/uniprot/G2LFN2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS14455 ^@ http://purl.uniprot.org/uniprot/G2LKS3 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/981222:CABTHER_RS00720 ^@ http://purl.uniprot.org/uniprot/G2LGG0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS08150 ^@ http://purl.uniprot.org/uniprot/G2LDE9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/981222:CABTHER_RS02190 ^@ http://purl.uniprot.org/uniprot/G2LHY6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/981222:CABTHER_RS08215 ^@ http://purl.uniprot.org/uniprot/G2LDG3 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/981222:CABTHER_RS02480 ^@ http://purl.uniprot.org/uniprot/G2LI45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS11510 ^@ http://purl.uniprot.org/uniprot/G2LJR6 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/981222:CABTHER_RS05875 ^@ http://purl.uniprot.org/uniprot/G2LD89 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/981222:CABTHER_RS03400 ^@ http://purl.uniprot.org/uniprot/G2LGU2 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/981222:CABTHER_RS04190 ^@ http://purl.uniprot.org/uniprot/G2LEE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS09165 ^@ http://purl.uniprot.org/uniprot/G2LGA2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/981222:CABTHER_RS00535 ^@ http://purl.uniprot.org/uniprot/G2LFF0 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/981222:CABTHER_RS07890 ^@ http://purl.uniprot.org/uniprot/G2LJ68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS14585 ^@ http://purl.uniprot.org/uniprot/G2LL31 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/981222:CABTHER_RS07390 ^@ http://purl.uniprot.org/uniprot/G2LIN4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/981222:CABTHER_RS13730 ^@ http://purl.uniprot.org/uniprot/G2LK49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliP/MopC/SpaP family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS01640 ^@ http://purl.uniprot.org/uniprot/G2LE34 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/981222:CABTHER_RS02195 ^@ http://purl.uniprot.org/uniprot/G2LHY7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/981222:CABTHER_RS01940 ^@ http://purl.uniprot.org/uniprot/G2LGP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS04085 ^@ http://purl.uniprot.org/uniprot/G2LIC7 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/981222:CABTHER_RS06335 ^@ http://purl.uniprot.org/uniprot/G2LEQ9 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/981222:CABTHER_RS01655 ^@ http://purl.uniprot.org/uniprot/G2LE37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS13345 ^@ http://purl.uniprot.org/uniprot/G2LLP3 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS03875 ^@ http://purl.uniprot.org/uniprot/G2LI85 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/981222:CABTHER_RS01545 ^@ http://purl.uniprot.org/uniprot/G2LE16 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/981222:CABTHER_RS03265 ^@ http://purl.uniprot.org/uniprot/G2LFL4 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/981222:CABTHER_RS09530 ^@ http://purl.uniprot.org/uniprot/G2LHM6 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS07995 ^@ http://purl.uniprot.org/uniprot/G2LJ91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS16235 ^@ http://purl.uniprot.org/uniprot/G2LK45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS03465 ^@ http://purl.uniprot.org/uniprot/G2LGV6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/981222:CABTHER_RS09265 ^@ http://purl.uniprot.org/uniprot/G2LGC2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS09795 ^@ http://purl.uniprot.org/uniprot/G2LIX6 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/981222:CABTHER_RS07800 ^@ http://purl.uniprot.org/uniprot/G2LJ49 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/981222:CABTHER_RS02235 ^@ http://purl.uniprot.org/uniprot/G2LHZ5 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/981222:CABTHER_RS12270 ^@ http://purl.uniprot.org/uniprot/G2LKF1 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/981222:CABTHER_RS08280 ^@ http://purl.uniprot.org/uniprot/G2LDH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS05020 ^@ http://purl.uniprot.org/uniprot/G2LH33 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/981222:CABTHER_RS08960 ^@ http://purl.uniprot.org/uniprot/G2LG60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/981222:CABTHER_RS03360 ^@ http://purl.uniprot.org/uniprot/G2LFN3 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/981222:CABTHER_RS08290 ^@ http://purl.uniprot.org/uniprot/G2LDH7 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/981222:CABTHER_RS09085 ^@ http://purl.uniprot.org/uniprot/G2LG86 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/981222:CABTHER_RS03485 ^@ http://purl.uniprot.org/uniprot/G2LGW0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS06835 ^@ http://purl.uniprot.org/uniprot/G2LG28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS01280 ^@ http://purl.uniprot.org/uniprot/G2LHW6 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/981222:CABTHER_RS06830 ^@ http://purl.uniprot.org/uniprot/G2LG27 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/981222:CABTHER_RS03795 ^@ http://purl.uniprot.org/uniprot/G2LI69 ^@ Similarity ^@ Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. http://togogenome.org/gene/981222:CABTHER_RS07040 ^@ http://purl.uniprot.org/uniprot/G2LHC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/981222:CABTHER_RS04280 ^@ http://purl.uniprot.org/uniprot/G2LEG1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/981222:CABTHER_RS06410 ^@ http://purl.uniprot.org/uniprot/G2LES3 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/981222:CABTHER_RS05410 ^@ http://purl.uniprot.org/uniprot/G2LIF4 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/981222:CABTHER_RS00355 ^@ http://purl.uniprot.org/uniprot/G2LFC0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS12085 ^@ http://purl.uniprot.org/uniprot/G2LK33 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/981222:CABTHER_RS05755 ^@ http://purl.uniprot.org/uniprot/G2LD63 ^@ Activity Regulation|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/981222:CABTHER_RS12140 ^@ http://purl.uniprot.org/uniprot/G2LKC5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS09715 ^@ http://purl.uniprot.org/uniprot/G2LIW0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/981222:CABTHER_RS01420 ^@ http://purl.uniprot.org/uniprot/G2LDZ2 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/981222:CABTHER_RS10575 ^@ http://purl.uniprot.org/uniprot/G2LDN8 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/981222:CABTHER_RS15410 ^@ http://purl.uniprot.org/uniprot/G2LGU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS08715 ^@ http://purl.uniprot.org/uniprot/G2LEZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMTC family.|||Endoplasmic reticulum|||Membrane http://togogenome.org/gene/981222:CABTHER_RS00125 ^@ http://purl.uniprot.org/uniprot/G2LDX6 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/981222:CABTHER_RS00555 ^@ http://purl.uniprot.org/uniprot/G2LFF4 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/981222:CABTHER_RS05055 ^@ http://purl.uniprot.org/uniprot/G2LH40 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/981222:CABTHER_RS06915 ^@ http://purl.uniprot.org/uniprot/G2LG44 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/981222:CABTHER_RS07455 ^@ http://purl.uniprot.org/uniprot/G2LIP7 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/981222:CABTHER_RS05185 ^@ http://purl.uniprot.org/uniprot/G2LH66 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS01495 ^@ http://purl.uniprot.org/uniprot/G2LE06 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/981222:CABTHER_RS09900 ^@ http://purl.uniprot.org/uniprot/G2LIZ7 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS10075 ^@ http://purl.uniprot.org/uniprot/G2LJ32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/981222:CABTHER_RS10070 ^@ http://purl.uniprot.org/uniprot/G2LJ31 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/981222:CABTHER_RS05970 ^@ http://purl.uniprot.org/uniprot/G2LDA8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS11910 ^@ http://purl.uniprot.org/uniprot/G2LJZ7 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/981222:CABTHER_RS03490 ^@ http://purl.uniprot.org/uniprot/G2LGW1 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/981222:CABTHER_RS05285 ^@ http://purl.uniprot.org/uniprot/G2LH86 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS02135 ^@ http://purl.uniprot.org/uniprot/G2LGT0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/981222:CABTHER_RS09045 ^@ http://purl.uniprot.org/uniprot/G2LG77 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS12195 ^@ http://purl.uniprot.org/uniprot/G2LKD6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS00530 ^@ http://purl.uniprot.org/uniprot/G2LFE9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/981222:CABTHER_RS15945 ^@ http://purl.uniprot.org/uniprot/G2LJ15 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/981222:CABTHER_RS05260 ^@ http://purl.uniprot.org/uniprot/G2LH81 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/981222:CABTHER_RS06875 ^@ http://purl.uniprot.org/uniprot/G2LG36 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/981222:CABTHER_RS00465 ^@ http://purl.uniprot.org/uniprot/G2LFD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS02570 ^@ http://purl.uniprot.org/uniprot/G2LI60 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/981222:CABTHER_RS01085 ^@ http://purl.uniprot.org/uniprot/G2LHT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS05695 ^@ http://purl.uniprot.org/uniprot/G2LIL3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS13690 ^@ http://purl.uniprot.org/uniprot/G2LLW6 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/981222:CABTHER_RS09825 ^@ http://purl.uniprot.org/uniprot/G2LIY2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS04405 ^@ http://purl.uniprot.org/uniprot/G2LEI6 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/981222:CABTHER_RS14355 ^@ http://purl.uniprot.org/uniprot/G2LKQ3 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS14495 ^@ http://purl.uniprot.org/uniprot/G2LKT1 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/981222:CABTHER_RS09340 ^@ http://purl.uniprot.org/uniprot/G2LHI6 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/981222:CABTHER_RS03090 ^@ http://purl.uniprot.org/uniprot/G2LFH8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/981222:CABTHER_RS01925 ^@ http://purl.uniprot.org/uniprot/G2LGN8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/981222:CABTHER_RS09895 ^@ http://purl.uniprot.org/uniprot/G2LIZ6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/981222:CABTHER_RS03200 ^@ http://purl.uniprot.org/uniprot/G2LFK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS08710 ^@ http://purl.uniprot.org/uniprot/G2LEY9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/981222:CABTHER_RS06855 ^@ http://purl.uniprot.org/uniprot/G2LG32 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/981222:CABTHER_RS08800 ^@ http://purl.uniprot.org/uniprot/G2LF08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS13915 ^@ http://purl.uniprot.org/uniprot/G2LK86 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/981222:CABTHER_RS04370 ^@ http://purl.uniprot.org/uniprot/G2LEH9 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/981222:CABTHER_RS14565 ^@ http://purl.uniprot.org/uniprot/G2LL27 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/981222:CABTHER_RS03470 ^@ http://purl.uniprot.org/uniprot/G2LGV7 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/981222:CABTHER_RS09960 ^@ http://purl.uniprot.org/uniprot/G2LJ09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS08790 ^@ http://purl.uniprot.org/uniprot/G2LF06 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS01650 ^@ http://purl.uniprot.org/uniprot/G2LE36 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS00080 ^@ http://purl.uniprot.org/uniprot/G2LDW7 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/981222:CABTHER_RS10160 ^@ http://purl.uniprot.org/uniprot/G2LJC8 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/981222:CABTHER_RS14190 ^@ http://purl.uniprot.org/uniprot/G2LKM0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/981222:CABTHER_RS13330 ^@ http://purl.uniprot.org/uniprot/G2LLP0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS13125 ^@ http://purl.uniprot.org/uniprot/G2LLD6 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/981222:CABTHER_RS02120 ^@ http://purl.uniprot.org/uniprot/G2LGS7 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/981222:CABTHER_RS09815 ^@ http://purl.uniprot.org/uniprot/G2LIY0 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/981222:CABTHER_RS02325 ^@ http://purl.uniprot.org/uniprot/G2LI14 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/981222:CABTHER_RS12760 ^@ http://purl.uniprot.org/uniprot/G2LKY1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS05815 ^@ http://purl.uniprot.org/uniprot/G2LD77 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS05190 ^@ http://purl.uniprot.org/uniprot/G2LH67 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/981222:CABTHER_RS07605 ^@ http://purl.uniprot.org/uniprot/G2LIS8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS13800 ^@ http://purl.uniprot.org/uniprot/G2LK63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/981222:CABTHER_RS02880 ^@ http://purl.uniprot.org/uniprot/G2LEB8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. http://togogenome.org/gene/981222:CABTHER_RS10055 ^@ http://purl.uniprot.org/uniprot/G2LJ28 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/981222:CABTHER_RS01365 ^@ http://purl.uniprot.org/uniprot/G2LHY3 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/981222:CABTHER_RS10500 ^@ http://purl.uniprot.org/uniprot/G2LDM2 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/981222:CABTHER_RS15990 ^@ http://purl.uniprot.org/uniprot/G2LJI8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS04215 ^@ http://purl.uniprot.org/uniprot/G2LEE8 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/981222:CABTHER_RS07410 ^@ http://purl.uniprot.org/uniprot/G2LIN8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS05485 ^@ http://purl.uniprot.org/uniprot/G2LIH1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/981222:CABTHER_RS14270 ^@ http://purl.uniprot.org/uniprot/G2LKN6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS02670 ^@ http://purl.uniprot.org/uniprot/G2LE74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/981222:CABTHER_RS11790 ^@ http://purl.uniprot.org/uniprot/G2LJX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the kinesin light chain family.|||cytoskeleton http://togogenome.org/gene/981222:CABTHER_RS05520 ^@ http://purl.uniprot.org/uniprot/G2LIH8 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/981222:CABTHER_RS01460 ^@ http://purl.uniprot.org/uniprot/G2LE00 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/981222:CABTHER_RS06525 ^@ http://purl.uniprot.org/uniprot/G2LEU6 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/981222:CABTHER_RS01905 ^@ http://purl.uniprot.org/uniprot/G2LGN3 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS03730 ^@ http://purl.uniprot.org/uniprot/G2LH11 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS03295 ^@ http://purl.uniprot.org/uniprot/G2LFM0 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/981222:CABTHER_RS09305 ^@ http://purl.uniprot.org/uniprot/G2LGD0 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/981222:CABTHER_RS14250 ^@ http://purl.uniprot.org/uniprot/G2LKN2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. http://togogenome.org/gene/981222:CABTHER_RS05530 ^@ http://purl.uniprot.org/uniprot/G2LII0 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/981222:CABTHER_RS08330 ^@ http://purl.uniprot.org/uniprot/G2LDI4 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/981222:CABTHER_RS02555 ^@ http://purl.uniprot.org/uniprot/G2LI57 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/981222:CABTHER_RS01970 ^@ http://purl.uniprot.org/uniprot/G2LGP7 ^@ Function|||Similarity ^@ Belongs to the Mg-chelatase subunits D/I family.|||Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. http://togogenome.org/gene/981222:CABTHER_RS16190 ^@ http://purl.uniprot.org/uniprot/G2LLF9 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/981222:CABTHER_RS04135 ^@ http://purl.uniprot.org/uniprot/G2LID7 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/981222:CABTHER_RS05610 ^@ http://purl.uniprot.org/uniprot/G2LIJ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/981222:CABTHER_RS12715 ^@ http://purl.uniprot.org/uniprot/G2LKX2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/981222:CABTHER_RS08225 ^@ http://purl.uniprot.org/uniprot/G2LDG4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/981222:CABTHER_RS08120 ^@ http://purl.uniprot.org/uniprot/G2LJB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS14470 ^@ http://purl.uniprot.org/uniprot/G2LKS6 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs.|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/981222:CABTHER_RS06090 ^@ http://purl.uniprot.org/uniprot/G2LDD4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS07690 ^@ http://purl.uniprot.org/uniprot/G2LIU5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/981222:CABTHER_RS12990 ^@ http://purl.uniprot.org/uniprot/G2LLB1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS07085 ^@ http://purl.uniprot.org/uniprot/G2LHC9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueG family.|||Binds 2 [4Fe-4S] clusters per monomer.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/981222:CABTHER_RS08320 ^@ http://purl.uniprot.org/uniprot/G2LDI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS13035 ^@ http://purl.uniprot.org/uniprot/G2LLB9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/981222:CABTHER_RS07150 ^@ http://purl.uniprot.org/uniprot/G2LHE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS07720 ^@ http://purl.uniprot.org/uniprot/G2LIV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS11440 ^@ http://purl.uniprot.org/uniprot/G2LJQ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/981222:CABTHER_RS14240 ^@ http://purl.uniprot.org/uniprot/G2LKN0 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/981222:CABTHER_RS08070 ^@ http://purl.uniprot.org/uniprot/G2LJA5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/981222:CABTHER_RS04185 ^@ http://purl.uniprot.org/uniprot/G2LEE2 ^@ Function ^@ Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/981222:CABTHER_RS14390 ^@ http://purl.uniprot.org/uniprot/G2LKR0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/981222:CABTHER_RS04305 ^@ http://purl.uniprot.org/uniprot/G2LEG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/981222:CABTHER_RS00320 ^@ http://purl.uniprot.org/uniprot/G2LFB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/981222:CABTHER_RS02400 ^@ http://purl.uniprot.org/uniprot/G2LI29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/981222:CABTHER_RS08380 ^@ http://purl.uniprot.org/uniprot/G2LDJ4 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/981222:CABTHER_RS14170 ^@ http://purl.uniprot.org/uniprot/G2LKL6 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/981222:CABTHER_RS05060 ^@ http://purl.uniprot.org/uniprot/G2LH41 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS03180 ^@ http://purl.uniprot.org/uniprot/G2LFJ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS13885 ^@ http://purl.uniprot.org/uniprot/G2LK80 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/981222:CABTHER_RS12025 ^@ http://purl.uniprot.org/uniprot/G2LK20 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS10640 ^@ http://purl.uniprot.org/uniprot/G2LDQ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/981222:CABTHER_RS10020 ^@ http://purl.uniprot.org/uniprot/G2LJ21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM19 family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS11805 ^@ http://purl.uniprot.org/uniprot/G2LJX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the kinesin light chain family.|||cytoskeleton http://togogenome.org/gene/981222:CABTHER_RS09480 ^@ http://purl.uniprot.org/uniprot/G2LHL4 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/981222:CABTHER_RS11375 ^@ http://purl.uniprot.org/uniprot/G2LJP0 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/981222:CABTHER_RS03855 ^@ http://purl.uniprot.org/uniprot/G2LI81 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/981222:CABTHER_RS01165 ^@ http://purl.uniprot.org/uniprot/G2LHU3 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/981222:CABTHER_RS11770 ^@ http://purl.uniprot.org/uniprot/G2LJW9 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/981222:CABTHER_RS07885 ^@ http://purl.uniprot.org/uniprot/G2LJ67 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS04710 ^@ http://purl.uniprot.org/uniprot/G2LFR9 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/981222:CABTHER_RS06820 ^@ http://purl.uniprot.org/uniprot/G2LG25 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/981222:CABTHER_RS15750 ^@ http://purl.uniprot.org/uniprot/G2LIN3 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnA subfamily.|||Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/981222:CABTHER_RS03880 ^@ http://purl.uniprot.org/uniprot/G2LI86 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/981222:CABTHER_RS15745 ^@ http://purl.uniprot.org/uniprot/G2LIN0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS08770 ^@ http://purl.uniprot.org/uniprot/G2LF02 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/981222:CABTHER_RS02130 ^@ http://purl.uniprot.org/uniprot/G2LGS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS11745 ^@ http://purl.uniprot.org/uniprot/G2LJW4 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/981222:CABTHER_RS17720 ^@ http://purl.uniprot.org/uniprot/G2LLL4 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/981222:CABTHER_RS09775 ^@ http://purl.uniprot.org/uniprot/G2LIX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS11755 ^@ http://purl.uniprot.org/uniprot/G2LJW6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS00585 ^@ http://purl.uniprot.org/uniprot/G2LGD3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/981222:CABTHER_RS07595 ^@ http://purl.uniprot.org/uniprot/G2LIS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS10895 ^@ http://purl.uniprot.org/uniprot/G2LF32 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/981222:CABTHER_RS08050 ^@ http://purl.uniprot.org/uniprot/G2LJA1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/981222:CABTHER_RS01370 ^@ http://purl.uniprot.org/uniprot/G2LHY4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/981222:CABTHER_RS07765 ^@ http://purl.uniprot.org/uniprot/G2LJ42 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/981222:CABTHER_RS12695 ^@ http://purl.uniprot.org/uniprot/G2LKW8 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/981222:CABTHER_RS00710 ^@ http://purl.uniprot.org/uniprot/G2LGF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS01005 ^@ http://purl.uniprot.org/uniprot/G2LHR7 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/981222:CABTHER_RS04445 ^@ http://purl.uniprot.org/uniprot/G2LEJ4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/981222:CABTHER_RS01170 ^@ http://purl.uniprot.org/uniprot/G2LHU4 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/981222:CABTHER_RS08085 ^@ http://purl.uniprot.org/uniprot/G2LJA7 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/981222:CABTHER_RS04325 ^@ http://purl.uniprot.org/uniprot/G2LEH0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS09785 ^@ http://purl.uniprot.org/uniprot/G2LIX4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS03185 ^@ http://purl.uniprot.org/uniprot/G2LFJ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS02995 ^@ http://purl.uniprot.org/uniprot/G2LFF9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/981222:CABTHER_RS07775 ^@ http://purl.uniprot.org/uniprot/G2LJ44 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/981222:CABTHER_RS13405 ^@ http://purl.uniprot.org/uniprot/G2LLQ4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/981222:CABTHER_RS11215 ^@ http://purl.uniprot.org/uniprot/G2LJK7 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/981222:CABTHER_RS09420 ^@ http://purl.uniprot.org/uniprot/G2LHK2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/981222:CABTHER_RS09445 ^@ http://purl.uniprot.org/uniprot/G2LHK7 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/981222:CABTHER_RS00070 ^@ http://purl.uniprot.org/uniprot/G2LDW4 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/981222:CABTHER_RS02115 ^@ http://purl.uniprot.org/uniprot/G2LGS6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/981222:CABTHER_RS01105 ^@ http://purl.uniprot.org/uniprot/G2LHT6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/981222:CABTHER_RS03965 ^@ http://purl.uniprot.org/uniprot/G2LIA3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/981222:CABTHER_RS13135 ^@ http://purl.uniprot.org/uniprot/G2LLD8 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/981222:CABTHER_RS12190 ^@ http://purl.uniprot.org/uniprot/G2LKD5 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/981222:CABTHER_RS12840 ^@ http://purl.uniprot.org/uniprot/G2LKZ7 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/981222:CABTHER_RS05445 ^@ http://purl.uniprot.org/uniprot/G2LIG1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS03675 ^@ http://purl.uniprot.org/uniprot/G2LGZ9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/981222:CABTHER_RS05580 ^@ http://purl.uniprot.org/uniprot/G2LIJ0 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/981222:CABTHER_RS07120 ^@ http://purl.uniprot.org/uniprot/G2LHD5 ^@ Similarity ^@ Belongs to the MscS (TC 1.A.23) family. http://togogenome.org/gene/981222:CABTHER_RS12160 ^@ http://purl.uniprot.org/uniprot/G2LKC9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/981222:CABTHER_RS03685 ^@ http://purl.uniprot.org/uniprot/G2LH01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS14420 ^@ http://purl.uniprot.org/uniprot/G2LKR6 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/981222:CABTHER_RS09790 ^@ http://purl.uniprot.org/uniprot/G2LIX5 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/981222:CABTHER_RS13120 ^@ http://purl.uniprot.org/uniprot/G2LLD5 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/981222:CABTHER_RS02330 ^@ http://purl.uniprot.org/uniprot/G2LI15 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/981222:CABTHER_RS03065 ^@ http://purl.uniprot.org/uniprot/G2LFH3 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/981222:CABTHER_RS08185 ^@ http://purl.uniprot.org/uniprot/G2LDF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/981222:CABTHER_RS05180 ^@ http://purl.uniprot.org/uniprot/G2LH65 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/981222:CABTHER_RS02395 ^@ http://purl.uniprot.org/uniprot/G2LI27 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/981222:CABTHER_RS10095 ^@ http://purl.uniprot.org/uniprot/G2LJ36 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/981222:CABTHER_RS10810 ^@ http://purl.uniprot.org/uniprot/G2LDT6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/981222:CABTHER_RS07700 ^@ http://purl.uniprot.org/uniprot/G2LIU7 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/981222:CABTHER_RS07280 ^@ http://purl.uniprot.org/uniprot/G2LHG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS04525 ^@ http://purl.uniprot.org/uniprot/G2LEL0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/981222:CABTHER_RS03545 ^@ http://purl.uniprot.org/uniprot/G2LGX4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/981222:CABTHER_RS00075 ^@ http://purl.uniprot.org/uniprot/G2LDW5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS13825 ^@ http://purl.uniprot.org/uniprot/G2LK68 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/981222:CABTHER_RS06365 ^@ http://purl.uniprot.org/uniprot/G2LER5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS08965 ^@ http://purl.uniprot.org/uniprot/G2LG61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/981222:CABTHER_RS02435 ^@ http://purl.uniprot.org/uniprot/G2LI36 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/981222:CABTHER_RS13990 ^@ http://purl.uniprot.org/uniprot/G2LKA2 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/981222:CABTHER_RS07420 ^@ http://purl.uniprot.org/uniprot/G2LIP0 ^@ Similarity ^@ Belongs to the ycf81 family. http://togogenome.org/gene/981222:CABTHER_RS15125 ^@ http://purl.uniprot.org/uniprot/G2LLM7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/981222:CABTHER_RS07820 ^@ http://purl.uniprot.org/uniprot/G2LJ54 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/981222:CABTHER_RS14460 ^@ http://purl.uniprot.org/uniprot/G2LKS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS06780 ^@ http://purl.uniprot.org/uniprot/G2LG17 ^@ Similarity ^@ Belongs to the AcsF family. http://togogenome.org/gene/981222:CABTHER_RS10150 ^@ http://purl.uniprot.org/uniprot/G2LJC6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS11070 ^@ http://purl.uniprot.org/uniprot/G2LF68 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS07345 ^@ http://purl.uniprot.org/uniprot/G2LIM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS02595 ^@ http://purl.uniprot.org/uniprot/G2LE61 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS06550 ^@ http://purl.uniprot.org/uniprot/G2LFX1 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/981222:CABTHER_RS09185 ^@ http://purl.uniprot.org/uniprot/G2LGA6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/981222:CABTHER_RS11040 ^@ http://purl.uniprot.org/uniprot/G2LF60 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/981222:CABTHER_RS00095 ^@ http://purl.uniprot.org/uniprot/G2LDX0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/981222:CABTHER_RS01340 ^@ http://purl.uniprot.org/uniprot/G2LHX8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/981222:CABTHER_RS16350 ^@ http://purl.uniprot.org/uniprot/G2LL91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS12850 ^@ http://purl.uniprot.org/uniprot/G2LKZ9 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/981222:CABTHER_RS09320 ^@ http://purl.uniprot.org/uniprot/G2LHI2 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/981222:CABTHER_RS02795 ^@ http://purl.uniprot.org/uniprot/G2LEA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS04735 ^@ http://purl.uniprot.org/uniprot/G2LFS4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/981222:CABTHER_RS03600 ^@ http://purl.uniprot.org/uniprot/G2LGY4 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/981222:CABTHER_RS12380 ^@ http://purl.uniprot.org/uniprot/G2LKH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS03420 ^@ http://purl.uniprot.org/uniprot/G2LGU7 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/981222:CABTHER_RS12135 ^@ http://purl.uniprot.org/uniprot/G2LKC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS14005 ^@ http://purl.uniprot.org/uniprot/G2LKA5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS03800 ^@ http://purl.uniprot.org/uniprot/G2LI70 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS02900 ^@ http://purl.uniprot.org/uniprot/G2LEC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/981222:CABTHER_RS12165 ^@ http://purl.uniprot.org/uniprot/G2LKD0 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS11485 ^@ http://purl.uniprot.org/uniprot/G2LJR1 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/981222:CABTHER_RS06965 ^@ http://purl.uniprot.org/uniprot/G2LHA4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/981222:CABTHER_RS01930 ^@ http://purl.uniprot.org/uniprot/G2LGN9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/981222:CABTHER_RS00760 ^@ http://purl.uniprot.org/uniprot/G2LGG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS03495 ^@ http://purl.uniprot.org/uniprot/G2LGW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS10105 ^@ http://purl.uniprot.org/uniprot/G2LJB6 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/981222:CABTHER_RS04725 ^@ http://purl.uniprot.org/uniprot/G2LFS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/981222:CABTHER_RS01585 ^@ http://purl.uniprot.org/uniprot/G2LE24 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S41B family.|||Cytoplasm|||Degrades oligopeptides. http://togogenome.org/gene/981222:CABTHER_RS08355 ^@ http://purl.uniprot.org/uniprot/G2LDI9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS14165 ^@ http://purl.uniprot.org/uniprot/G2LKL5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnC family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/981222:CABTHER_RS13105 ^@ http://purl.uniprot.org/uniprot/G2LLD2 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/981222:CABTHER_RS13650 ^@ http://purl.uniprot.org/uniprot/G2LLV8 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS11165 ^@ http://purl.uniprot.org/uniprot/G2LJJ7 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS07580 ^@ http://purl.uniprot.org/uniprot/G2LIS3 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/981222:CABTHER_RS11935 ^@ http://purl.uniprot.org/uniprot/G2LK02 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/981222:CABTHER_RS00730 ^@ http://purl.uniprot.org/uniprot/G2LGG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/981222:CABTHER_RS10335 ^@ http://purl.uniprot.org/uniprot/G2LJG3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. http://togogenome.org/gene/981222:CABTHER_RS00895 ^@ http://purl.uniprot.org/uniprot/G2LGJ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/981222:CABTHER_RS08975 ^@ http://purl.uniprot.org/uniprot/G2LG63 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/981222:CABTHER_RS10265 ^@ http://purl.uniprot.org/uniprot/G2LJF0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/981222:CABTHER_RS09730 ^@ http://purl.uniprot.org/uniprot/G2LIW3 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/981222:CABTHER_RS02560 ^@ http://purl.uniprot.org/uniprot/G2LI58 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/981222:CABTHER_RS04895 ^@ http://purl.uniprot.org/uniprot/G2LFV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS05935 ^@ http://purl.uniprot.org/uniprot/G2LDA1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS07965 ^@ http://purl.uniprot.org/uniprot/G2LJ84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS11060 ^@ http://purl.uniprot.org/uniprot/G2LF66 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/981222:CABTHER_RS01955 ^@ http://purl.uniprot.org/uniprot/G2LGP4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/981222:CABTHER_RS10050 ^@ http://purl.uniprot.org/uniprot/G2LJ27 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/981222:CABTHER_RS00905 ^@ http://purl.uniprot.org/uniprot/G2LGJ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS13665 ^@ http://purl.uniprot.org/uniprot/G2LLW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/981222:CABTHER_RS06710 ^@ http://purl.uniprot.org/uniprot/G2LG03 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/981222:CABTHER_RS12805 ^@ http://purl.uniprot.org/uniprot/G2LKZ0 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/981222:CABTHER_RS00395 ^@ http://purl.uniprot.org/uniprot/G2LFC8 ^@ Similarity ^@ Belongs to the BshC family. http://togogenome.org/gene/981222:CABTHER_RS05550 ^@ http://purl.uniprot.org/uniprot/G2LII4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/981222:CABTHER_RS10975 ^@ http://purl.uniprot.org/uniprot/G2LF47 ^@ Function ^@ Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. http://togogenome.org/gene/981222:CABTHER_RS13890 ^@ http://purl.uniprot.org/uniprot/G2LK81 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/981222:CABTHER_RS14090 ^@ http://purl.uniprot.org/uniprot/G2LKC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS15080 ^@ http://purl.uniprot.org/uniprot/G2LLL7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/981222:CABTHER_RS14755 ^@ http://purl.uniprot.org/uniprot/G2LL67 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/981222:CABTHER_RS13625 ^@ http://purl.uniprot.org/uniprot/G2LLV1 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/981222:CABTHER_RS01400 ^@ http://purl.uniprot.org/uniprot/G2LDY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS02455 ^@ http://purl.uniprot.org/uniprot/G2LI40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS11630 ^@ http://purl.uniprot.org/uniprot/G2LJU0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/981222:CABTHER_RS10255 ^@ http://purl.uniprot.org/uniprot/G2LJE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS01435 ^@ http://purl.uniprot.org/uniprot/G2LDZ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS11365 ^@ http://purl.uniprot.org/uniprot/G2LJN8 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS11220 ^@ http://purl.uniprot.org/uniprot/G2LJK8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS15220 ^@ http://purl.uniprot.org/uniprot/G2LHR4 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/981222:CABTHER_RS02745 ^@ http://purl.uniprot.org/uniprot/G2LE90 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/981222:CABTHER_RS06670 ^@ http://purl.uniprot.org/uniprot/G2LFZ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/981222:CABTHER_RS10745 ^@ http://purl.uniprot.org/uniprot/G2LDS2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS02680 ^@ http://purl.uniprot.org/uniprot/G2LE76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/981222:CABTHER_RS01830 ^@ http://purl.uniprot.org/uniprot/G2LGL9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS06760 ^@ http://purl.uniprot.org/uniprot/G2LG13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS17295 ^@ http://purl.uniprot.org/uniprot/G2LKC0 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/981222:CABTHER_RS09560 ^@ http://purl.uniprot.org/uniprot/G2LHN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS02605 ^@ http://purl.uniprot.org/uniprot/G2LE63 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS08955 ^@ http://purl.uniprot.org/uniprot/G2LG59 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/981222:CABTHER_RS00545 ^@ http://purl.uniprot.org/uniprot/G2LFF2 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/981222:CABTHER_RS07235 ^@ http://purl.uniprot.org/uniprot/G2LHF8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/981222:CABTHER_RS06205 ^@ http://purl.uniprot.org/uniprot/G2LEN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS10245 ^@ http://purl.uniprot.org/uniprot/G2LJE6 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/981222:CABTHER_RS00630 ^@ http://purl.uniprot.org/uniprot/G2LGE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/981222:CABTHER_RS04360 ^@ http://purl.uniprot.org/uniprot/G2LEH7 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/981222:CABTHER_RS00450 ^@ http://purl.uniprot.org/uniprot/G2LFD4 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/981222:CABTHER_RS06545 ^@ http://purl.uniprot.org/uniprot/G2LFX0 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/981222:CABTHER_RS11450 ^@ http://purl.uniprot.org/uniprot/G2LJQ4 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/981222:CABTHER_RS03725 ^@ http://purl.uniprot.org/uniprot/G2LH10 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS11610 ^@ http://purl.uniprot.org/uniprot/G2LJT7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS06920 ^@ http://purl.uniprot.org/uniprot/G2LG46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS01960 ^@ http://purl.uniprot.org/uniprot/G2LGP5 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/981222:CABTHER_RS05510 ^@ http://purl.uniprot.org/uniprot/G2LIH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/981222:CABTHER_RS07870 ^@ http://purl.uniprot.org/uniprot/G2LJ64 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/981222:CABTHER_RS14105 ^@ http://purl.uniprot.org/uniprot/G2LKK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/981222:CABTHER_RS03780 ^@ http://purl.uniprot.org/uniprot/G2LI66 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS12315 ^@ http://purl.uniprot.org/uniprot/G2LKG0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/981222:CABTHER_RS13635 ^@ http://purl.uniprot.org/uniprot/G2LLV4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS03865 ^@ http://purl.uniprot.org/uniprot/G2LI83 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/981222:CABTHER_RS12575 ^@ http://purl.uniprot.org/uniprot/G2LKU4 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/981222:CABTHER_RS00345 ^@ http://purl.uniprot.org/uniprot/G2LFB8 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/981222:CABTHER_RS00640 ^@ http://purl.uniprot.org/uniprot/G2LGE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/981222:CABTHER_RS01415 ^@ http://purl.uniprot.org/uniprot/G2LDZ1 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/981222:CABTHER_RS02610 ^@ http://purl.uniprot.org/uniprot/G2LE64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Cytoplasm http://togogenome.org/gene/981222:CABTHER_RS11035 ^@ http://purl.uniprot.org/uniprot/G2LF59 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/981222:CABTHER_RS02165 ^@ http://purl.uniprot.org/uniprot/G2LGT6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/981222:CABTHER_RS05505 ^@ http://purl.uniprot.org/uniprot/G2LIH5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/981222:CABTHER_RS04950 ^@ http://purl.uniprot.org/uniprot/G2LFW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/981222:CABTHER_RS16105 ^@ http://purl.uniprot.org/uniprot/G2LJY2 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/981222:CABTHER_RS04470 ^@ http://purl.uniprot.org/uniprot/G2LEJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS06720 ^@ http://purl.uniprot.org/uniprot/G2LG05 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/981222:CABTHER_RS14485 ^@ http://purl.uniprot.org/uniprot/G2LKS9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/981222:CABTHER_RS06530 ^@ http://purl.uniprot.org/uniprot/G2LEU7 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/981222:CABTHER_RS06730 ^@ http://purl.uniprot.org/uniprot/G2LG07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/981222:CABTHER_RS02315 ^@ http://purl.uniprot.org/uniprot/G2LI12 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/981222:CABTHER_RS06045 ^@ http://purl.uniprot.org/uniprot/G2LDC4 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/981222:CABTHER_RS06775 ^@ http://purl.uniprot.org/uniprot/G2LG16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/981222:CABTHER_RS06370 ^@ http://purl.uniprot.org/uniprot/G2LER6 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation.