http://togogenome.org/gene/991789:CPRO_RS00580 ^@ http://purl.uniprot.org/uniprot/A0A0X8V7T8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell membrane|||Component of the transport system for branched-chain amino acids.|||Membrane http://togogenome.org/gene/991789:CPRO_RS00445 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB59 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/991789:CPRO_RS15635 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS01945 ^@ http://purl.uniprot.org/uniprot/A0A110A6P7 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/991789:CPRO_RS04005 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCM2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS07920 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8G4 ^@ Function|||Similarity ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). http://togogenome.org/gene/991789:CPRO_RS07305 ^@ http://purl.uniprot.org/uniprot/A0A0X1U844 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/991789:CPRO_RS11610 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBG5 ^@ Similarity|||Subunit ^@ Belongs to the MtrB family.|||Oligomer of 11 identical subunits arranged in doughnut-like structure. http://togogenome.org/gene/991789:CPRO_RS04120 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCX1 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS06530 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7N7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS14360 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/991789:CPRO_RS03970 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/991789:CPRO_RS00025 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/991789:CPRO_RS13390 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCA2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/991789:CPRO_RS12235 ^@ http://purl.uniprot.org/uniprot/A0A120MKF0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/991789:CPRO_RS02605 ^@ http://purl.uniprot.org/uniprot/A0A110A6U9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS00390 ^@ http://purl.uniprot.org/uniprot/A0A110A6X1 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/991789:CPRO_RS02470 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBM2 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/991789:CPRO_RS03605 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC28 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/991789:CPRO_RS07260 ^@ http://purl.uniprot.org/uniprot/A0A0X1U838 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS00840 ^@ http://purl.uniprot.org/uniprot/A0A110A6Z0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/991789:CPRO_RS11480 ^@ http://purl.uniprot.org/uniprot/A0A110A7C3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS05450 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6Y9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS02160 ^@ http://purl.uniprot.org/uniprot/A0A120MK37 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/991789:CPRO_RS01910 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8F2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/991789:CPRO_RS07415 ^@ http://purl.uniprot.org/uniprot/A0A0X1U871 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/991789:CPRO_RS06940 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7V8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/991789:CPRO_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9J7 ^@ Function|||Similarity ^@ Belongs to the mannonate dehydratase family.|||Catalyzes the dehydration of D-mannonate. http://togogenome.org/gene/991789:CPRO_RS03980 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAE9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/991789:CPRO_RS00640 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9B2 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBB9 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/991789:CPRO_RS11020 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDB2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/991789:CPRO_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS03640 ^@ http://purl.uniprot.org/uniprot/A0A0X8V936 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS00685 ^@ http://purl.uniprot.org/uniprot/A0A120MK07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/991789:CPRO_RS12895 ^@ http://purl.uniprot.org/uniprot/A0A120MKG3 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/991789:CPRO_RS02385 ^@ http://purl.uniprot.org/uniprot/A0A110A6R9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS07195 ^@ http://purl.uniprot.org/uniprot/A0A0X1U801 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/991789:CPRO_RS03740 ^@ http://purl.uniprot.org/uniprot/A0A110A6Y1 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival. http://togogenome.org/gene/991789:CPRO_RS07770 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8E0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/991789:CPRO_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A0X1U842 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/991789:CPRO_RS05715 ^@ http://purl.uniprot.org/uniprot/A0A0X1U753 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/991789:CPRO_RS02670 ^@ http://purl.uniprot.org/uniprot/A0A110A753 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/991789:CPRO_RS11205 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDM0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/991789:CPRO_RS10020 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDA6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/991789:CPRO_RS06185 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7F3 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/991789:CPRO_RS04660 ^@ http://purl.uniprot.org/uniprot/A0A110A7D8 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/991789:CPRO_RS00095 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS10490 ^@ http://purl.uniprot.org/uniprot/A0A110A756 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/991789:CPRO_RS13190 ^@ http://purl.uniprot.org/uniprot/A0A110A7I1 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS02725 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9X7 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/991789:CPRO_RS00145 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB20 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/991789:CPRO_RS04620 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD16 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS09915 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS11365 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDA7 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/991789:CPRO_RS05630 ^@ http://purl.uniprot.org/uniprot/A0A0X1U739 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS13335 ^@ http://purl.uniprot.org/uniprot/A0A110A7K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS01720 ^@ http://purl.uniprot.org/uniprot/A0A0X8V895 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M3B family.|||Binds 1 zinc ion.|||Has oligopeptidase activity and degrades a variety of small bioactive peptides. http://togogenome.org/gene/991789:CPRO_RS13415 ^@ http://purl.uniprot.org/uniprot/A0A120MKH3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS14315 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS02595 ^@ http://purl.uniprot.org/uniprot/A0A120MK45 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/991789:CPRO_RS02755 ^@ http://purl.uniprot.org/uniprot/A0A110A711 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/991789:CPRO_RS04970 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6P9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/991789:CPRO_RS02945 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA34 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/991789:CPRO_RS03550 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAE3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS00595 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB83 ^@ Caution|||Similarity ^@ Belongs to the peptidase S8 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS11390 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBD2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS01385 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBQ5 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/991789:CPRO_RS07855 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8D6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/991789:CPRO_RS12840 ^@ http://purl.uniprot.org/uniprot/A0A0X8VED2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/991789:CPRO_RS12725 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAS4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS12470 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE79 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/991789:CPRO_RS07650 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8A4 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/991789:CPRO_RS11370 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDT3 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS13010 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/991789:CPRO_RS01055 ^@ http://purl.uniprot.org/uniprot/A0A110A6Y8 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/991789:CPRO_RS09315 ^@ http://purl.uniprot.org/uniprot/A0A0X1U987 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS02195 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9W1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/991789:CPRO_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCM1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/991789:CPRO_RS10065 ^@ http://purl.uniprot.org/uniprot/A0A110A777 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/991789:CPRO_RS08390 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8Q7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS07945 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS02290 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8H0 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/991789:CPRO_RS11465 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBH3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit.|||Heterotetramer of 2 PyrK and 2 PyrD type B subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). http://togogenome.org/gene/991789:CPRO_RS00030 ^@ http://purl.uniprot.org/uniprot/A0A0X8V937 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/991789:CPRO_RS12230 ^@ http://purl.uniprot.org/uniprot/A0A110A7J4 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/991789:CPRO_RS14235 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS10565 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS09950 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCW0 ^@ Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. http://togogenome.org/gene/991789:CPRO_RS04455 ^@ http://purl.uniprot.org/uniprot/A0A110A725 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/991789:CPRO_RS11990 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAH8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS10770 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA28 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/991789:CPRO_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBF5 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/991789:CPRO_RS05190 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6V5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS07885 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8F7 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/991789:CPRO_RS04325 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCX6 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/991789:CPRO_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7Z8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS11050 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA56 ^@ Similarity ^@ Belongs to the FBPase class 3 family. http://togogenome.org/gene/991789:CPRO_RS13865 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliN/MopA/SpaO family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS09865 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD57 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/991789:CPRO_RS02715 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCA6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/991789:CPRO_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBU0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/991789:CPRO_RS05570 ^@ http://purl.uniprot.org/uniprot/A0A0X1U726 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS05035 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6S2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS02545 ^@ http://purl.uniprot.org/uniprot/A0A120MK43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8B1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/991789:CPRO_RS10015 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCW8 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/991789:CPRO_RS09985 ^@ http://purl.uniprot.org/uniprot/A0A110A761 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/991789:CPRO_RS12890 ^@ http://purl.uniprot.org/uniprot/A0A120MKG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/991789:CPRO_RS03745 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC50 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/991789:CPRO_RS05185 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6V6 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/991789:CPRO_RS07585 ^@ http://purl.uniprot.org/uniprot/A0A0X1U886 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS01125 ^@ http://purl.uniprot.org/uniprot/A0A110A6P4 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS00130 ^@ http://purl.uniprot.org/uniprot/A0A0X8V7N2 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/991789:CPRO_RS02995 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCE1 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS01315 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBP4 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/991789:CPRO_RS02405 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS01185 ^@ http://purl.uniprot.org/uniprot/A0A0X8V826 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS02600 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/991789:CPRO_RS06235 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A120MK12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/991789:CPRO_RS01625 ^@ http://purl.uniprot.org/uniprot/A0A120MK27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS12930 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC03 ^@ Similarity ^@ Belongs to the UPF0297 family. http://togogenome.org/gene/991789:CPRO_RS07440 ^@ http://purl.uniprot.org/uniprot/A0A0X1U856 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS09980 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD36 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/991789:CPRO_RS11135 ^@ http://purl.uniprot.org/uniprot/A0A110A7A4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/991789:CPRO_RS04750 ^@ http://purl.uniprot.org/uniprot/A0A110A797 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS14130 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEZ3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Requires K(+) for maximal activity.|||Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. http://togogenome.org/gene/991789:CPRO_RS02645 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA20 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/991789:CPRO_RS12605 ^@ http://purl.uniprot.org/uniprot/A0A110A7Z8 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/991789:CPRO_RS01775 ^@ http://purl.uniprot.org/uniprot/A0A110A6T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBT0 ^@ Similarity ^@ Belongs to the UPF0751 family. http://togogenome.org/gene/991789:CPRO_RS07380 ^@ http://purl.uniprot.org/uniprot/A0A0X1U850 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/991789:CPRO_RS14085 ^@ http://purl.uniprot.org/uniprot/A0A110A7N5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/991789:CPRO_RS09755 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD08 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS09050 ^@ http://purl.uniprot.org/uniprot/A0A0X1U939 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/991789:CPRO_RS01345 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAX1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/991789:CPRO_RS10025 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB02 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS07250 ^@ http://purl.uniprot.org/uniprot/A0A0X1U835 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS03545 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS12390 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDN8 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/991789:CPRO_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAA1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/991789:CPRO_RS02815 ^@ http://purl.uniprot.org/uniprot/A0A120MK49 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS01130 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBF7 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/991789:CPRO_RS13820 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEP4 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/991789:CPRO_RS12625 ^@ http://purl.uniprot.org/uniprot/A0A0X8VED8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS02480 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9Z9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class U subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/991789:CPRO_RS07275 ^@ http://purl.uniprot.org/uniprot/A0A0X1U836 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/991789:CPRO_RS11530 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBL8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS09840 ^@ http://purl.uniprot.org/uniprot/A0A110A730 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS13435 ^@ http://purl.uniprot.org/uniprot/A0A110A7L9 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/991789:CPRO_RS03555 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA93 ^@ Function|||Similarity ^@ Belongs to the V-ATPase E subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/991789:CPRO_RS12720 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBY6 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/991789:CPRO_RS08720 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8V6 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/991789:CPRO_RS11470 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAB0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS12195 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS04110 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCU4 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase family. http://togogenome.org/gene/991789:CPRO_RS12780 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEF8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/991789:CPRO_RS08605 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8T0 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/991789:CPRO_RS12450 ^@ http://purl.uniprot.org/uniprot/A0A120MKF5 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/991789:CPRO_RS01180 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9F9 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/991789:CPRO_RS05655 ^@ http://purl.uniprot.org/uniprot/A0A0X1U750 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/991789:CPRO_RS09765 ^@ http://purl.uniprot.org/uniprot/A0A120MKA0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/991789:CPRO_RS08870 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8Y0 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/991789:CPRO_RS10485 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS02610 ^@ http://purl.uniprot.org/uniprot/A0A120MK46 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/991789:CPRO_RS11085 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDN3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/991789:CPRO_RS04510 ^@ http://purl.uniprot.org/uniprot/A0A110A744 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/991789:CPRO_RS02675 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC29 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/991789:CPRO_RS04770 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCL5 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/991789:CPRO_RS13455 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS00180 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAX0 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS06115 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7E4 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/991789:CPRO_RS02745 ^@ http://purl.uniprot.org/uniprot/A0A110A6W4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/991789:CPRO_RS11345 ^@ http://purl.uniprot.org/uniprot/A0A110A7B2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS01830 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8A5 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS00035 ^@ http://purl.uniprot.org/uniprot/A0A0X8V910 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/991789:CPRO_RS00305 ^@ http://purl.uniprot.org/uniprot/A0A110A6K3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS01400 ^@ http://purl.uniprot.org/uniprot/A0A0X8V855 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/991789:CPRO_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A0X1U921 ^@ Function|||Similarity ^@ Belongs to the transposase IS30 family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/991789:CPRO_RS06075 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7C7 ^@ Similarity ^@ Belongs to the ycf81 family. http://togogenome.org/gene/991789:CPRO_RS03310 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBY5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS01430 ^@ http://purl.uniprot.org/uniprot/A0A110A6M4 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/991789:CPRO_RS14560 ^@ http://purl.uniprot.org/uniprot/A0A120MKK0 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/991789:CPRO_RS05625 ^@ http://purl.uniprot.org/uniprot/A0A0X1U745 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS12590 ^@ http://purl.uniprot.org/uniprot/A0A110A7D9 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/991789:CPRO_RS09940 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCQ0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/991789:CPRO_RS00525 ^@ http://purl.uniprot.org/uniprot/A0A110A6L0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/991789:CPRO_RS10440 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCX7 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/991789:CPRO_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBV7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7Z0 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/991789:CPRO_RS01970 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBY1 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/991789:CPRO_RS14100 ^@ http://purl.uniprot.org/uniprot/A0A120MKJ0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/991789:CPRO_RS12535 ^@ http://purl.uniprot.org/uniprot/A0A110A7I5 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/991789:CPRO_RS07420 ^@ http://purl.uniprot.org/uniprot/A0A0X1U866 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS03375 ^@ http://purl.uniprot.org/uniprot/A0A110A700 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/991789:CPRO_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A110A6Q7 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/991789:CPRO_RS08470 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8S2 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/991789:CPRO_RS14470 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS00165 ^@ http://purl.uniprot.org/uniprot/A0A110A6W0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/991789:CPRO_RS12350 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAL8 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/991789:CPRO_RS12900 ^@ http://purl.uniprot.org/uniprot/A0A120MKG6 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/991789:CPRO_RS12240 ^@ http://purl.uniprot.org/uniprot/A0A120MKE8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/991789:CPRO_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A110A6S8 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS07100 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7Z2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS12730 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAR7 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/991789:CPRO_RS14745 ^@ http://purl.uniprot.org/uniprot/A0A0X8VF83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/991789:CPRO_RS12695 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDY1 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/991789:CPRO_RS05750 ^@ http://purl.uniprot.org/uniprot/A0A0X1U756 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS11170 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDT5 ^@ Function|||Similarity|||Subunit ^@ Associates with stalled 50S ribosomal subunits.|||Belongs to the NEMF family.|||Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. http://togogenome.org/gene/991789:CPRO_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A0X8V971 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/991789:CPRO_RS09550 ^@ http://purl.uniprot.org/uniprot/A0A0X1U9D6 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/991789:CPRO_RS01955 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC19 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS07105 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7Y3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/991789:CPRO_RS13230 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEM3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily.|||Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS08395 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8P4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS06265 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS07280 ^@ http://purl.uniprot.org/uniprot/A0A0X1U823 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS09835 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD18 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A120MJZ8 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/991789:CPRO_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A0X1U785 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS12985 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/991789:CPRO_RS10935 ^@ http://purl.uniprot.org/uniprot/A0A110A7J3 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/991789:CPRO_RS02765 ^@ http://purl.uniprot.org/uniprot/A0A120MK47 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/991789:CPRO_RS03340 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA64 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/991789:CPRO_RS02295 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8L0 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/991789:CPRO_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A110A783 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/991789:CPRO_RS11620 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS01550 ^@ http://purl.uniprot.org/uniprot/A0A0X8V875 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS12745 ^@ http://purl.uniprot.org/uniprot/A0A110A7G3 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/991789:CPRO_RS12670 ^@ http://purl.uniprot.org/uniprot/A0A120MKG0 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/991789:CPRO_RS07995 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8H1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS07845 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8D8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS07435 ^@ http://purl.uniprot.org/uniprot/A0A0X1U861 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/991789:CPRO_RS05975 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7B5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS11960 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE15 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/991789:CPRO_RS10690 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB67 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/991789:CPRO_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A120MK41 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS14285 ^@ http://purl.uniprot.org/uniprot/A0A0X8VF15 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS13860 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEU7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS11150 ^@ http://purl.uniprot.org/uniprot/A0A110A7C2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/991789:CPRO_RS00530 ^@ http://purl.uniprot.org/uniprot/A0A120MK05 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/991789:CPRO_RS01535 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9N1 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/991789:CPRO_RS10415 ^@ http://purl.uniprot.org/uniprot/A0A120MKB1 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS05900 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7A0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS14540 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBF0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS00815 ^@ http://purl.uniprot.org/uniprot/A0A110A6X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS00850 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBL9 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/991789:CPRO_RS13465 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCB3 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/991789:CPRO_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBN2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS05835 ^@ http://purl.uniprot.org/uniprot/A0A0X1U786 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/991789:CPRO_RS11925 ^@ http://purl.uniprot.org/uniprot/A0A110A7I0 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/991789:CPRO_RS13980 ^@ http://purl.uniprot.org/uniprot/A0A110A7K3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/991789:CPRO_RS09895 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9Q6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS04035 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCT3 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/991789:CPRO_RS11575 ^@ http://purl.uniprot.org/uniprot/A0A110A7E5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcAL family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS01905 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8B5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/991789:CPRO_RS12915 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/991789:CPRO_RS06660 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7R1 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/991789:CPRO_RS10930 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA43 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/991789:CPRO_RS00865 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBI0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/991789:CPRO_RS10175 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB26 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS10195 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9U4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS14510 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEL9 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/991789:CPRO_RS04350 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9B8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/991789:CPRO_RS13995 ^@ http://purl.uniprot.org/uniprot/A0A110A852 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS01170 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9K5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/991789:CPRO_RS01265 ^@ http://purl.uniprot.org/uniprot/A0A0X8V872 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS04485 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS13890 ^@ http://purl.uniprot.org/uniprot/A0A120MKI6 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/991789:CPRO_RS12105 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDJ4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/991789:CPRO_RS14705 ^@ http://purl.uniprot.org/uniprot/A0A0X8VF13 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/991789:CPRO_RS02705 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC97 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/991789:CPRO_RS13045 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS07535 ^@ http://purl.uniprot.org/uniprot/A0A0X1U880 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS00615 ^@ http://purl.uniprot.org/uniprot/A0A110A6X9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/991789:CPRO_RS07450 ^@ http://purl.uniprot.org/uniprot/A0A0X1U867 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/991789:CPRO_RS10420 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD98 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS02680 ^@ http://purl.uniprot.org/uniprot/A0A110A6S6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/991789:CPRO_RS02825 ^@ http://purl.uniprot.org/uniprot/A0A110A6V8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/991789:CPRO_RS04615 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS03305 ^@ http://purl.uniprot.org/uniprot/A0A110A6V4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS02970 ^@ http://purl.uniprot.org/uniprot/A0A110A721 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/991789:CPRO_RS01640 ^@ http://purl.uniprot.org/uniprot/A0A120MK26 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/991789:CPRO_RS14755 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCN2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/991789:CPRO_RS03130 ^@ http://purl.uniprot.org/uniprot/A0A110A6U6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS01405 ^@ http://purl.uniprot.org/uniprot/A0A120MK22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS07245 ^@ http://purl.uniprot.org/uniprot/A0A0X1U811 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/991789:CPRO_RS11450 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDX2 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/991789:CPRO_RS05660 ^@ http://purl.uniprot.org/uniprot/A0A0X1U744 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/991789:CPRO_RS07990 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8H4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS09925 ^@ http://purl.uniprot.org/uniprot/A0A120MK98 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/991789:CPRO_RS04530 ^@ http://purl.uniprot.org/uniprot/A0A120MK89 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/991789:CPRO_RS06270 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7H0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS02030 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC30 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/991789:CPRO_RS10535 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB76 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS00860 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB62 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/991789:CPRO_RS01915 ^@ http://purl.uniprot.org/uniprot/A0A120MK29 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/991789:CPRO_RS03395 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCI9 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/991789:CPRO_RS08185 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8L2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC59 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/991789:CPRO_RS02660 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8M5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/991789:CPRO_RS02390 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBL3 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/991789:CPRO_RS11140 ^@ http://purl.uniprot.org/uniprot/A0A120MKC6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/991789:CPRO_RS11525 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS04955 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6P7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/991789:CPRO_RS00670 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB94 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/991789:CPRO_RS11385 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBJ9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS02800 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS05610 ^@ http://purl.uniprot.org/uniprot/A0A0X1U734 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS03710 ^@ http://purl.uniprot.org/uniprot/A0A0X8V945 ^@ Similarity ^@ Belongs to the DNA polymerase type-A family. http://togogenome.org/gene/991789:CPRO_RS00155 ^@ http://purl.uniprot.org/uniprot/A0A110A6L2 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/991789:CPRO_RS09860 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCP0 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/991789:CPRO_RS15830 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/991789:CPRO_RS01045 ^@ http://purl.uniprot.org/uniprot/A0A0X8V805 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS12250 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDL7 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/991789:CPRO_RS00515 ^@ http://purl.uniprot.org/uniprot/A0A120MK01 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/991789:CPRO_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC72 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS08230 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8P2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS01060 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBE7 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/991789:CPRO_RS12315 ^@ http://purl.uniprot.org/uniprot/A0A110A7H3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS12510 ^@ http://purl.uniprot.org/uniprot/A0A120MKF6 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/991789:CPRO_RS00125 ^@ http://purl.uniprot.org/uniprot/A0A0X8V920 ^@ Function|||Similarity ^@ Belongs to the desulfoferrodoxin family.|||Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity. http://togogenome.org/gene/991789:CPRO_RS03580 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCF9 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/991789:CPRO_RS12265 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE81 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/991789:CPRO_RS11455 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBK8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS06370 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7J4 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/991789:CPRO_RS11485 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDR5 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/991789:CPRO_RS03945 ^@ http://purl.uniprot.org/uniprot/A0A110A733 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/991789:CPRO_RS01395 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9H5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/991789:CPRO_RS09815 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAT5 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/991789:CPRO_RS10410 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9X3 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/991789:CPRO_RS11005 ^@ http://purl.uniprot.org/uniprot/A0A110A7P6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the flotillin-like FloA family.|||Cell membrane|||Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.|||Homooligomerizes.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane raft http://togogenome.org/gene/991789:CPRO_RS14545 ^@ http://purl.uniprot.org/uniprot/A0A110A7Q7 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/991789:CPRO_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9Q9 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Binds 1 Ca(2+) ion per subunit.|||Cytoplasm|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS11630 ^@ http://purl.uniprot.org/uniprot/A0A110A7M2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/991789:CPRO_RS08225 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8M1 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/991789:CPRO_RS05935 ^@ http://purl.uniprot.org/uniprot/A0A0X1U790 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/991789:CPRO_RS09935 ^@ http://purl.uniprot.org/uniprot/A0A120MK97 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/991789:CPRO_RS07400 ^@ http://purl.uniprot.org/uniprot/A0A0X1U854 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/991789:CPRO_RS04470 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD00 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/991789:CPRO_RS14080 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS00475 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBG8 ^@ Caution|||Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS08140 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS04480 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD28 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS06955 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7V6 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/991789:CPRO_RS02720 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA31 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/991789:CPRO_RS11775 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDV0 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/991789:CPRO_RS14010 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS13710 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCD9 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/991789:CPRO_RS00830 ^@ http://purl.uniprot.org/uniprot/A0A110A6P0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/991789:CPRO_RS02535 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/991789:CPRO_RS09285 ^@ http://purl.uniprot.org/uniprot/A0A0X1U972 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/991789:CPRO_RS01215 ^@ http://purl.uniprot.org/uniprot/A0A110A6R8 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/991789:CPRO_RS13170 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAX2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/991789:CPRO_RS02125 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9P9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS04490 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAM2 ^@ Function ^@ Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/991789:CPRO_RS06565 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7N2 ^@ Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. http://togogenome.org/gene/991789:CPRO_RS13830 ^@ http://purl.uniprot.org/uniprot/A0A120MKI7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/991789:CPRO_RS09170 ^@ http://purl.uniprot.org/uniprot/A0A0X1U935 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/991789:CPRO_RS06275 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7I1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS14135 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS10660 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD03 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS06260 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS09945 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD68 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/991789:CPRO_RS04360 ^@ http://purl.uniprot.org/uniprot/A0A120MK87 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/991789:CPRO_RS03995 ^@ http://purl.uniprot.org/uniprot/A0A0X8V983 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/991789:CPRO_RS14750 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/991789:CPRO_RS10760 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB63 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/991789:CPRO_RS12365 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE31 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpB family.|||Cytoplasm|||Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/991789:CPRO_RS06205 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7F9 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/991789:CPRO_RS02700 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBQ4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/991789:CPRO_RS10525 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD34 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/991789:CPRO_RS07365 ^@ http://purl.uniprot.org/uniprot/A0A0X1U858 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/991789:CPRO_RS12620 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/991789:CPRO_RS08535 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8S5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS13370 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE28 ^@ Caution|||Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS12520 ^@ http://purl.uniprot.org/uniprot/A0A110A7F3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/991789:CPRO_RS11100 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBG2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/991789:CPRO_RS14655 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEP5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS13870 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCB1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS12660 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE75 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/991789:CPRO_RS12810 ^@ http://purl.uniprot.org/uniprot/A0A110A7R3 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/991789:CPRO_RS02920 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS12155 ^@ http://purl.uniprot.org/uniprot/A0A110A7C1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/991789:CPRO_RS05865 ^@ http://purl.uniprot.org/uniprot/A0A0X1U788 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS03000 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS12500 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAP1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/991789:CPRO_RS09590 ^@ http://purl.uniprot.org/uniprot/A0A0X1U9B8 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/991789:CPRO_RS07620 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8A5 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/991789:CPRO_RS00555 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB25 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/991789:CPRO_RS00405 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB01 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TenA family.|||Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.|||Homotetramer. http://togogenome.org/gene/991789:CPRO_RS11605 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBM8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS06505 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7M0 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/991789:CPRO_RS01260 ^@ http://purl.uniprot.org/uniprot/A0A0X8V837 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS06230 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7G3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS01380 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBC4 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/991789:CPRO_RS11435 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS14440 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS01120 ^@ http://purl.uniprot.org/uniprot/A0A0X8V850 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/991789:CPRO_RS04370 ^@ http://purl.uniprot.org/uniprot/A0A110A726 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/991789:CPRO_RS02085 ^@ http://purl.uniprot.org/uniprot/A0A120MK34 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/991789:CPRO_RS01930 ^@ http://purl.uniprot.org/uniprot/A0A110A6S1 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/991789:CPRO_RS09240 ^@ http://purl.uniprot.org/uniprot/A0A0X1U958 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/991789:CPRO_RS11550 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAC0 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/991789:CPRO_RS13250 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAZ9 ^@ Similarity ^@ Belongs to the UPF0371 family. http://togogenome.org/gene/991789:CPRO_RS12645 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAR5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS08215 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8I7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS08855 ^@ http://purl.uniprot.org/uniprot/A0A0X1U911 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/991789:CPRO_RS11475 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAA9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS00395 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS12335 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS07265 ^@ http://purl.uniprot.org/uniprot/A0A0X1U837 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/991789:CPRO_RS14430 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEL2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/991789:CPRO_RS05065 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6R7 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/991789:CPRO_RS00825 ^@ http://purl.uniprot.org/uniprot/A0A110A6J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS02205 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9R9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/991789:CPRO_RS08250 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8N4 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/991789:CPRO_RS13470 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC74 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/991789:CPRO_RS11825 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RecU family.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS12405 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEA5 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/991789:CPRO_RS01665 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBG3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/991789:CPRO_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBD7 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/991789:CPRO_RS03215 ^@ http://purl.uniprot.org/uniprot/A0A120MK58 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/991789:CPRO_RS13895 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEQ6 ^@ Similarity ^@ Belongs to the FlgD family. http://togogenome.org/gene/991789:CPRO_RS02805 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8P4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.|||Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).|||Membrane http://togogenome.org/gene/991789:CPRO_RS10725 ^@ http://purl.uniprot.org/uniprot/A0A110A790 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/991789:CPRO_RS12735 ^@ http://purl.uniprot.org/uniprot/A0A120MKG2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. http://togogenome.org/gene/991789:CPRO_RS12120 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE58 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/991789:CPRO_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A0X8V829 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS04975 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS14725 ^@ http://purl.uniprot.org/uniprot/A0A110A873 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/991789:CPRO_RS04475 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS02150 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBU8 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/991789:CPRO_RS03570 ^@ http://purl.uniprot.org/uniprot/A0A0X8V926 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/991789:CPRO_RS00215 ^@ http://purl.uniprot.org/uniprot/A0A110A6L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS00290 ^@ http://purl.uniprot.org/uniprot/A0A0X8V7T9 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/991789:CPRO_RS06895 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7V9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/991789:CPRO_RS01425 ^@ http://purl.uniprot.org/uniprot/A0A110A6S7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/991789:CPRO_RS14585 ^@ http://purl.uniprot.org/uniprot/A0A0X8VF64 ^@ Function|||Similarity ^@ Belongs to the transferase hexapeptide repeat family. DapH subfamily.|||Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. http://togogenome.org/gene/991789:CPRO_RS05755 ^@ http://purl.uniprot.org/uniprot/A0A0X1U751 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/991789:CPRO_RS14520 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCN9 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/991789:CPRO_RS04950 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6Q0 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/991789:CPRO_RS09970 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9R3 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/991789:CPRO_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS08730 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8X2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS00610 ^@ http://purl.uniprot.org/uniprot/A0A110A6K9 ^@ Function|||Similarity ^@ Belongs to the Thz kinase family.|||Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). http://togogenome.org/gene/991789:CPRO_RS03385 ^@ http://purl.uniprot.org/uniprot/A0A110A7D2 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/991789:CPRO_RS02710 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/991789:CPRO_RS08255 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8M3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/991789:CPRO_RS14210 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEU9 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/991789:CPRO_RS12480 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEB6 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/991789:CPRO_RS01175 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9G2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/991789:CPRO_RS12490 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBU2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS07720 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8C7 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/991789:CPRO_RS13110 ^@ http://purl.uniprot.org/uniprot/A0A120MKH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS11155 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/991789:CPRO_RS04355 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9D1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS13245 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC44 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/991789:CPRO_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A0X1U713 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/991789:CPRO_RS03005 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCF8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/991789:CPRO_RS00560 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBD0 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/991789:CPRO_RS03405 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCL0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/991789:CPRO_RS03280 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCA7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/991789:CPRO_RS03915 ^@ http://purl.uniprot.org/uniprot/A0A0X8V975 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/991789:CPRO_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9W6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/991789:CPRO_RS06010 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7C6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS12185 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDQ7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/991789:CPRO_RS01415 ^@ http://purl.uniprot.org/uniprot/A0A110A6Q0 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/991789:CPRO_RS03295 ^@ http://purl.uniprot.org/uniprot/A0A110A703 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/991789:CPRO_RS00540 ^@ http://purl.uniprot.org/uniprot/A0A110A6J2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/991789:CPRO_RS09880 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAY3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/991789:CPRO_RS07595 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8A0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/991789:CPRO_RS06485 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7M5 ^@ Similarity ^@ Belongs to the plasmid mobilization pre family. http://togogenome.org/gene/991789:CPRO_RS12290 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAK6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/991789:CPRO_RS07470 ^@ http://purl.uniprot.org/uniprot/A0A0X1U875 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9F3 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/991789:CPRO_RS12285 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/991789:CPRO_RS01575 ^@ http://purl.uniprot.org/uniprot/A0A120MK25 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/991789:CPRO_RS14565 ^@ http://purl.uniprot.org/uniprot/A0A120MKJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9Z7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/991789:CPRO_RS03585 ^@ http://purl.uniprot.org/uniprot/A0A110A6W2 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/991789:CPRO_RS12750 ^@ http://purl.uniprot.org/uniprot/A0A120MKG1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS02080 ^@ http://purl.uniprot.org/uniprot/A0A110A6Y2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/991789:CPRO_RS03020 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/991789:CPRO_RS12330 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE87 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/991789:CPRO_RS11515 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS14700 ^@ http://purl.uniprot.org/uniprot/A0A110A833 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/991789:CPRO_RS00070 ^@ http://purl.uniprot.org/uniprot/A0A110A6J5 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/991789:CPRO_RS05025 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6Q5 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/991789:CPRO_RS13975 ^@ http://purl.uniprot.org/uniprot/A0A0X8VER5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/991789:CPRO_RS10045 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9S5 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/991789:CPRO_RS04945 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6Q3 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/991789:CPRO_RS07710 ^@ http://purl.uniprot.org/uniprot/A0A0X1U893 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyl-CoA hydrolase/transferase family.|||Coenzyme A-transferase that converts butyrate to butyryl-CoA.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS11600 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDZ3 ^@ Similarity ^@ Belongs to the pyruvate kinase family.|||In the C-terminal section; belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/991789:CPRO_RS05115 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6S6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS04300 ^@ http://purl.uniprot.org/uniprot/A0A110A779 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/991789:CPRO_RS05180 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6V0 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS03630 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAB4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS12475 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDU9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/991789:CPRO_RS04605 ^@ http://purl.uniprot.org/uniprot/A0A110A762 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS01455 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9M8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS09150 ^@ http://purl.uniprot.org/uniprot/A0A0X1U957 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/991789:CPRO_RS00955 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9C9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS00195 ^@ http://purl.uniprot.org/uniprot/A0A0X8V932 ^@ Caution|||Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Belongs to the MsrB Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.|||In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.|||In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS03190 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8U8 ^@ Similarity ^@ Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family. http://togogenome.org/gene/991789:CPRO_RS00330 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB99 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS06850 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7U2 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/991789:CPRO_RS09905 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9Q3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS12325 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDS7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/991789:CPRO_RS03275 ^@ http://purl.uniprot.org/uniprot/A0A120MK61 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS11635 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDT1 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/991789:CPRO_RS09845 ^@ http://purl.uniprot.org/uniprot/A0A110A767 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/991789:CPRO_RS07475 ^@ http://purl.uniprot.org/uniprot/A0A0X1U872 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/991789:CPRO_RS12690 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEB5 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/991789:CPRO_RS02350 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8I1 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/991789:CPRO_RS09965 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9R5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Cell membrane|||Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).|||Membrane http://togogenome.org/gene/991789:CPRO_RS10615 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB33 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.|||Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS01590 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBX5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. AddA subfamily.|||Heterodimer of AddA and AddB/RexB.|||The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities. http://togogenome.org/gene/991789:CPRO_RS00365 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB49 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS08100 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8I0 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/991789:CPRO_RS08240 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS07810 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8B3 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/991789:CPRO_RS05885 ^@ http://purl.uniprot.org/uniprot/A0A0X1U789 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS08620 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8T2 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/991789:CPRO_RS08715 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8X3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8T1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the energy-coupling factor EcfT family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).|||Membrane|||Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. http://togogenome.org/gene/991789:CPRO_RS03530 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC18 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/991789:CPRO_RS00695 ^@ http://purl.uniprot.org/uniprot/A0A120MK02 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/991789:CPRO_RS13845 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE92 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/991789:CPRO_RS12270 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/991789:CPRO_RS09930 ^@ http://purl.uniprot.org/uniprot/A0A120MK99 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/991789:CPRO_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA58 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/991789:CPRO_RS12755 ^@ http://purl.uniprot.org/uniprot/A0A110A7I9 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.|||Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid. http://togogenome.org/gene/991789:CPRO_RS13800 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC99 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS11040 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBB5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS11080 ^@ http://purl.uniprot.org/uniprot/A0A120MKC4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/991789:CPRO_RS09875 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD84 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/991789:CPRO_RS10185 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAZ3 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/991789:CPRO_RS11445 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDG7 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/991789:CPRO_RS00380 ^@ http://purl.uniprot.org/uniprot/A0A110A6M3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/991789:CPRO_RS08775 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8Y9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS12100 ^@ http://purl.uniprot.org/uniprot/A0A110A7F9 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/991789:CPRO_RS11225 ^@ http://purl.uniprot.org/uniprot/A0A110A7Q5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS12680 ^@ http://purl.uniprot.org/uniprot/A0A120MKF8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/991789:CPRO_RS13715 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC96 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/991789:CPRO_RS01275 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBI1 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/991789:CPRO_RS05770 ^@ http://purl.uniprot.org/uniprot/A0A0X1U768 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/991789:CPRO_RS06190 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7F1 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/991789:CPRO_RS03115 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8W9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS14105 ^@ http://purl.uniprot.org/uniprot/A0A120MKI9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS02980 ^@ http://purl.uniprot.org/uniprot/A0A120MK53 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.|||This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. http://togogenome.org/gene/991789:CPRO_RS06525 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7M9 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS06280 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7H4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS05095 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6S9 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS11175 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/991789:CPRO_RS04930 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS00310 ^@ http://purl.uniprot.org/uniprot/A0A120MJZ7 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/991789:CPRO_RS14185 ^@ http://purl.uniprot.org/uniprot/A0A110A7R0 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/991789:CPRO_RS06085 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7E0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/991789:CPRO_RS01660 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBY7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/991789:CPRO_RS06450 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7K1 ^@ Caution|||Similarity ^@ Belongs to the soluble Thoeris ThsA family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS07330 ^@ http://purl.uniprot.org/uniprot/A0A0X1U834 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS14075 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS05765 ^@ http://purl.uniprot.org/uniprot/A0A0X1U761 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS04105 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCA4 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/991789:CPRO_RS11915 ^@ http://purl.uniprot.org/uniprot/A0A110A7E0 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/991789:CPRO_RS07860 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8D4 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase family. http://togogenome.org/gene/991789:CPRO_RS04585 ^@ http://purl.uniprot.org/uniprot/A0A120MK90 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/991789:CPRO_RS05795 ^@ http://purl.uniprot.org/uniprot/A0A0X1U766 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/991789:CPRO_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A0X1U758 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/991789:CPRO_RS03510 ^@ http://purl.uniprot.org/uniprot/A0A120MK67 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS07490 ^@ http://purl.uniprot.org/uniprot/A0A0X1U869 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS13040 ^@ http://purl.uniprot.org/uniprot/A0A110A818 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS10670 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD54 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/991789:CPRO_RS12740 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE84 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/991789:CPRO_RS00205 ^@ http://purl.uniprot.org/uniprot/A0A0X8V7P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS07925 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8D3 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS02465 ^@ http://purl.uniprot.org/uniprot/A0A110A765 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/991789:CPRO_RS04595 ^@ http://purl.uniprot.org/uniprot/A0A110A740 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS00810 ^@ http://purl.uniprot.org/uniprot/A0A0X8V808 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS05195 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS08495 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8S7 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/991789:CPRO_RS05955 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7B2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS05700 ^@ http://purl.uniprot.org/uniprot/A0A0X1U746 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/991789:CPRO_RS07220 ^@ http://purl.uniprot.org/uniprot/A0A0X1U825 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/991789:CPRO_RS12570 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAQ5 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/991789:CPRO_RS01725 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8D5 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/991789:CPRO_RS10030 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAV7 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/991789:CPRO_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A110A6N9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/991789:CPRO_RS07295 ^@ http://purl.uniprot.org/uniprot/A0A0X1U833 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/991789:CPRO_RS01255 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9G7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS13780 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/991789:CPRO_RS03985 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS02165 ^@ http://purl.uniprot.org/uniprot/A0A110A6V6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS06555 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7N0 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/991789:CPRO_RS10430 ^@ http://purl.uniprot.org/uniprot/A0A110A7A3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. http://togogenome.org/gene/991789:CPRO_RS03220 ^@ http://purl.uniprot.org/uniprot/A0A120MK59 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/991789:CPRO_RS00975 ^@ http://purl.uniprot.org/uniprot/A0A120MK08 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/991789:CPRO_RS11130 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDL0 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/991789:CPRO_RS03575 ^@ http://purl.uniprot.org/uniprot/A0A110A794 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/991789:CPRO_RS12130 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBN5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS01560 ^@ http://purl.uniprot.org/uniprot/A0A110A6R3 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/991789:CPRO_RS07335 ^@ http://purl.uniprot.org/uniprot/A0A0X1U839 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/991789:CPRO_RS07605 ^@ http://purl.uniprot.org/uniprot/A0A0X1U873 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS00460 ^@ http://purl.uniprot.org/uniprot/A0A120MJZ9 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/991789:CPRO_RS01280 ^@ http://purl.uniprot.org/uniprot/A0A110A6L4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.|||Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS13300 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE56 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/991789:CPRO_RS12150 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE00 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/991789:CPRO_RS13355 ^@ http://purl.uniprot.org/uniprot/A0A120MKH7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS14270 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEE0 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/991789:CPRO_RS05810 ^@ http://purl.uniprot.org/uniprot/A0A0X1U776 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/991789:CPRO_RS14760 ^@ http://purl.uniprot.org/uniprot/A0A110A6M9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8D7 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/991789:CPRO_RS04650 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9J1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS03455 ^@ http://purl.uniprot.org/uniprot/A0A120MK66 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/991789:CPRO_RS13350 ^@ http://purl.uniprot.org/uniprot/A0A110A7N9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS08785 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8W9 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/991789:CPRO_RS10890 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBS9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecU family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation. http://togogenome.org/gene/991789:CPRO_RS10215 ^@ http://purl.uniprot.org/uniprot/A0A120MKA6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/991789:CPRO_RS06915 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7X0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/991789:CPRO_RS14735 ^@ http://purl.uniprot.org/uniprot/A0A0X8VF28 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpB RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpA.|||Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H). http://togogenome.org/gene/991789:CPRO_RS10940 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDI3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS02640 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC89 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/991789:CPRO_RS02695 ^@ http://purl.uniprot.org/uniprot/A0A110A775 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/991789:CPRO_RS13880 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS13720 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC91 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/991789:CPRO_RS07210 ^@ http://purl.uniprot.org/uniprot/A0A0X1U827 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS08195 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8J3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/991789:CPRO_RS14145 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/991789:CPRO_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC70 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS07775 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8D5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS05105 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6T3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS02335 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/991789:CPRO_RS03025 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA46 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/991789:CPRO_RS04775 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD38 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS07780 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8C9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS01310 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBB2 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/991789:CPRO_RS14435 ^@ http://purl.uniprot.org/uniprot/A0A0X8VF41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS00400 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBF9 ^@ Similarity ^@ Belongs to the ThrE exporter (TC 2.A.79) family. http://togogenome.org/gene/991789:CPRO_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCC4 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/991789:CPRO_RS13835 ^@ http://purl.uniprot.org/uniprot/A0A120MKI3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/991789:CPRO_RS01245 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9K9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/991789:CPRO_RS13450 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEL8 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/991789:CPRO_RS13090 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAW5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS14220 ^@ http://purl.uniprot.org/uniprot/A0A0X8VF04 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/991789:CPRO_RS13020 ^@ http://purl.uniprot.org/uniprot/A0A110A7R9 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS12190 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protease PrsW family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS06985 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7X4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCS3 ^@ Similarity ^@ Belongs to the acylphosphatase family.|||Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/991789:CPRO_RS05165 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6T4 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/991789:CPRO_RS12400 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS07700 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8B7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell membrane|||Component of the transport system for branched-chain amino acids.|||Membrane http://togogenome.org/gene/991789:CPRO_RS14505 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEZ6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS13205 ^@ http://purl.uniprot.org/uniprot/A0A110A7L0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS13060 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEK2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS10755 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/991789:CPRO_RS06535 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7N6 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/991789:CPRO_RS10675 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDL2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS14600 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCK5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/991789:CPRO_RS04985 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6R4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS00755 ^@ http://purl.uniprot.org/uniprot/A0A110A6M0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/991789:CPRO_RS02780 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBW2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/991789:CPRO_RS14120 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEU4 ^@ Similarity ^@ Belongs to the MecA family. http://togogenome.org/gene/991789:CPRO_RS01860 ^@ http://purl.uniprot.org/uniprot/A0A120MK31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/991789:CPRO_RS11555 ^@ http://purl.uniprot.org/uniprot/A0A120MKD6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/991789:CPRO_RS00505 ^@ http://purl.uniprot.org/uniprot/A0A0X8V7S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS11645 ^@ http://purl.uniprot.org/uniprot/A0A110A7D4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/991789:CPRO_RS02960 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8V0 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/991789:CPRO_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7G5 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/991789:CPRO_RS08675 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8W5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS14715 ^@ http://purl.uniprot.org/uniprot/A0A110A7Q4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/991789:CPRO_RS13875 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCB2 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/991789:CPRO_RS05920 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7A5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell membrane|||Component of the transport system for branched-chain amino acids.|||Membrane http://togogenome.org/gene/991789:CPRO_RS09810 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the P(II) protein family.|||Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS01530 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBS7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8U1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/991789:CPRO_RS09220 ^@ http://purl.uniprot.org/uniprot/A0A0X1U949 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS11570 ^@ http://purl.uniprot.org/uniprot/A0A120MKD7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/991789:CPRO_RS08330 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8N6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS01375 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBU3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/991789:CPRO_RS12465 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDP7 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/991789:CPRO_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9P1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/991789:CPRO_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8M1 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/991789:CPRO_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A120MK36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS04645 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAQ4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/991789:CPRO_RS12815 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE95 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/991789:CPRO_RS08670 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8U0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS11460 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBE2 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS06995 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7W8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS10190 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9U5 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/991789:CPRO_RS10060 ^@ http://purl.uniprot.org/uniprot/A0A110A737 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/991789:CPRO_RS07235 ^@ http://purl.uniprot.org/uniprot/A0A0X1U830 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS00510 ^@ http://purl.uniprot.org/uniprot/A0A0X8V7X0 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/991789:CPRO_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCI0 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily. http://togogenome.org/gene/991789:CPRO_RS05820 ^@ http://purl.uniprot.org/uniprot/A0A0X1U782 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS10925 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MrnC RNase family.|||Cytoplasm|||Homodimer.|||Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. http://togogenome.org/gene/991789:CPRO_RS00635 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBE4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS13165 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAY8 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/991789:CPRO_RS13200 ^@ http://purl.uniprot.org/uniprot/A0A110A7K9 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/991789:CPRO_RS02665 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8R3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/991789:CPRO_RS03265 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8W0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/991789:CPRO_RS01740 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBP1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS01440 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBV5 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS09485 ^@ http://purl.uniprot.org/uniprot/A0A0X1U9B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS11160 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDP5 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/991789:CPRO_RS00385 ^@ http://purl.uniprot.org/uniprot/A0A110A6K2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/991789:CPRO_RS07430 ^@ http://purl.uniprot.org/uniprot/A0A0X1U863 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/991789:CPRO_RS07600 ^@ http://purl.uniprot.org/uniprot/A0A0X1U896 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS02285 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9T0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS02280 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9S0 ^@ Similarity ^@ Belongs to the UPF0735 family. http://togogenome.org/gene/991789:CPRO_RS10230 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCU1 ^@ Similarity ^@ Belongs to the peptidase C59 family. http://togogenome.org/gene/991789:CPRO_RS05590 ^@ http://purl.uniprot.org/uniprot/A0A0X1U737 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS01420 ^@ http://purl.uniprot.org/uniprot/A0A120MK18 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/991789:CPRO_RS01005 ^@ http://purl.uniprot.org/uniprot/A0A110A6K8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS01975 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9T1 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/991789:CPRO_RS13155 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC41 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8V8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS02250 ^@ http://purl.uniprot.org/uniprot/A0A110A754 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS12375 ^@ http://purl.uniprot.org/uniprot/A0A110A7G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS14290 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCK9 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/991789:CPRO_RS14255 ^@ http://purl.uniprot.org/uniprot/A0A110A7N4 ^@ Similarity ^@ Belongs to the ThiD family. http://togogenome.org/gene/991789:CPRO_RS06250 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7G8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS12610 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDS5 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/991789:CPRO_RS01925 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBR0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers). http://togogenome.org/gene/991789:CPRO_RS00150 ^@ http://purl.uniprot.org/uniprot/A0A110A6H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS04250 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCW5 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/991789:CPRO_RS02860 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCD3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/991789:CPRO_RS04590 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCW7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/991789:CPRO_RS02040 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS05775 ^@ http://purl.uniprot.org/uniprot/A0A0X1U769 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/991789:CPRO_RS05965 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7A9 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/991789:CPRO_RS00105 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAV9 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/991789:CPRO_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A0X1U748 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. C-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/991789:CPRO_RS07485 ^@ http://purl.uniprot.org/uniprot/A0A0X1U868 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS10775 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA25 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS07000 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7X8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS13260 ^@ http://purl.uniprot.org/uniprot/A0A110A7S9 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/991789:CPRO_RS12525 ^@ http://purl.uniprot.org/uniprot/A0A120MKF7 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/991789:CPRO_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9V0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/991789:CPRO_RS07405 ^@ http://purl.uniprot.org/uniprot/A0A0X1U841 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/991789:CPRO_RS11420 ^@ http://purl.uniprot.org/uniprot/A0A110A7C4 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/991789:CPRO_RS12305 ^@ http://purl.uniprot.org/uniprot/A0A110A7E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS02965 ^@ http://purl.uniprot.org/uniprot/A0A110A6X6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/991789:CPRO_RS10805 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD37 ^@ Function|||Subcellular Location Annotation ^@ ATPase. Has a role at an early stage in the morphogenesis of the spore coat.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS10655 ^@ http://purl.uniprot.org/uniprot/A0A110A768 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs.|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/991789:CPRO_RS11075 ^@ http://purl.uniprot.org/uniprot/A0A120MKC3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/991789:CPRO_RS00060 ^@ http://purl.uniprot.org/uniprot/A0A120MJY9 ^@ Similarity ^@ Belongs to the diacylglycerol/lipid kinase family. http://togogenome.org/gene/991789:CPRO_RS03030 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8S7 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/991789:CPRO_RS11590 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/991789:CPRO_RS11165 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDC9 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/991789:CPRO_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A0X8V982 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS05945 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7A1 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/991789:CPRO_RS13050 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/991789:CPRO_RS02770 ^@ http://purl.uniprot.org/uniprot/A0A120MK54 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/991789:CPRO_RS11045 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA51 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS10625 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA02 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/991789:CPRO_RS06100 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7E1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/991789:CPRO_RS08130 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS02975 ^@ http://purl.uniprot.org/uniprot/A0A120MK55 ^@ Similarity ^@ Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family. http://togogenome.org/gene/991789:CPRO_RS02875 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS12370 ^@ http://purl.uniprot.org/uniprot/A0A110A7D0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpA family.|||Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Cytoplasm|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/991789:CPRO_RS03415 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA77 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/991789:CPRO_RS02735 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8N4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/991789:CPRO_RS13725 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB57 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS02440 ^@ http://purl.uniprot.org/uniprot/A0A110A743 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS04270 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAJ0 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/991789:CPRO_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8J4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS06255 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7H3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS05055 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6R8 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS07360 ^@ http://purl.uniprot.org/uniprot/A0A0X1U860 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/991789:CPRO_RS00450 ^@ http://purl.uniprot.org/uniprot/A0A110A6R6 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/991789:CPRO_RS01135 ^@ http://purl.uniprot.org/uniprot/A0A110A6U2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS07580 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8A1 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS12965 ^@ http://purl.uniprot.org/uniprot/A0A120MKG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A110A704 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/991789:CPRO_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A0X8V972 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/991789:CPRO_RS10860 ^@ http://purl.uniprot.org/uniprot/A0A120MKC1 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/991789:CPRO_RS00190 ^@ http://purl.uniprot.org/uniprot/A0A0X8V958 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS13960 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB92 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/991789:CPRO_RS12630 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/991789:CPRO_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A0X1U793 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/991789:CPRO_RS13805 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB69 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/991789:CPRO_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCD2 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/991789:CPRO_RS10570 ^@ http://purl.uniprot.org/uniprot/A0A110A7C9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/991789:CPRO_RS10435 ^@ http://purl.uniprot.org/uniprot/A0A110A758 ^@ Function|||Similarity ^@ Belongs to the anti-sigma-factor family.|||Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. http://togogenome.org/gene/991789:CPRO_RS06160 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7F6 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/991789:CPRO_RS01595 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBF3 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/991789:CPRO_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBS4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/991789:CPRO_RS02400 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS13030 ^@ http://purl.uniprot.org/uniprot/A0A110A7I7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS12095 ^@ http://purl.uniprot.org/uniprot/A0A110A7G5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS10735 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD24 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/991789:CPRO_RS12805 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS09675 ^@ http://purl.uniprot.org/uniprot/A0A0X1U9G0 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/991789:CPRO_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6W1 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/991789:CPRO_RS07270 ^@ http://purl.uniprot.org/uniprot/A0A0X1U832 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/991789:CPRO_RS01145 ^@ http://purl.uniprot.org/uniprot/A0A120MK15 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/991789:CPRO_RS12170 ^@ http://purl.uniprot.org/uniprot/A0A110A7X8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/991789:CPRO_RS06570 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7N1 ^@ Function ^@ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. http://togogenome.org/gene/991789:CPRO_RS00795 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9B4 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/991789:CPRO_RS12635 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBW1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/991789:CPRO_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A120MJZ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/991789:CPRO_RS14730 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEK4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS07755 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8D1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/991789:CPRO_RS03960 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCS2 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/991789:CPRO_RS14490 ^@ http://purl.uniprot.org/uniprot/A0A110A7R6 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/991789:CPRO_RS01230 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/991789:CPRO_RS03950 ^@ http://purl.uniprot.org/uniprot/A0A110A6Y7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS14090 ^@ http://purl.uniprot.org/uniprot/A0A0X8VES0 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/991789:CPRO_RS11115 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA65 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/991789:CPRO_RS05465 ^@ http://purl.uniprot.org/uniprot/A0A0X1U708 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS02655 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9Y6 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/991789:CPRO_RS00480 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB13 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS06125 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7D8 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/991789:CPRO_RS14365 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS12835 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDV5 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/991789:CPRO_RS06015 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7B9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS10720 ^@ http://purl.uniprot.org/uniprot/A0A110A7A1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A110A6Q1 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/991789:CPRO_RS07625 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8A2 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/991789:CPRO_RS08490 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8R2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/991789:CPRO_RS06375 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7J8 ^@ Similarity ^@ Belongs to the YoeB family. http://togogenome.org/gene/991789:CPRO_RS09600 ^@ http://purl.uniprot.org/uniprot/A0A0X1U9E6 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/991789:CPRO_RS04830 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6M1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS02425 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9V6 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/991789:CPRO_RS13760 ^@ http://purl.uniprot.org/uniprot/A0A110A7P2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/991789:CPRO_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8T3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8G8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/991789:CPRO_RS04905 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6N9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/991789:CPRO_RS12995 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC64 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/991789:CPRO_RS00200 ^@ http://purl.uniprot.org/uniprot/A0A0X8V938 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/991789:CPRO_RS07635 ^@ http://purl.uniprot.org/uniprot/A0A0X1U899 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/991789:CPRO_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A0X1U702 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. Flotillin subfamily. http://togogenome.org/gene/991789:CPRO_RS12865 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS06245 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7H6 ^@ Similarity ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family. http://togogenome.org/gene/991789:CPRO_RS00775 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBK9 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/991789:CPRO_RS14310 ^@ http://purl.uniprot.org/uniprot/A0A110A7P5 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS03560 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAA7 ^@ Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family. http://togogenome.org/gene/991789:CPRO_RS13445 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE43 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/991789:CPRO_RS02630 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC90 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/991789:CPRO_RS06835 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7T3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/991789:CPRO_RS13785 ^@ http://purl.uniprot.org/uniprot/A0A0X8VET8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/991789:CPRO_RS00160 ^@ http://purl.uniprot.org/uniprot/A0A110A6J4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS10715 ^@ http://purl.uniprot.org/uniprot/A0A110A766 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/991789:CPRO_RS06990 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7W7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/991789:CPRO_RS14405 ^@ http://purl.uniprot.org/uniprot/A0A110A7Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS08825 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8Z7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS04655 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9I1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS04100 ^@ http://purl.uniprot.org/uniprot/A0A120MK83 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/991789:CPRO_RS10740 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDJ6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/991789:CPRO_RS13430 ^@ http://purl.uniprot.org/uniprot/A0A120MKH4 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/991789:CPRO_RS06665 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7R7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RecU family.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS14500 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEH1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/991789:CPRO_RS01330 ^@ http://purl.uniprot.org/uniprot/A0A0X8V842 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/991789:CPRO_RS14195 ^@ http://purl.uniprot.org/uniprot/A0A110A7P7 ^@ Cofactor ^@ Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/991789:CPRO_RS04045 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCW2 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/991789:CPRO_RS10005 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCQ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/991789:CPRO_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A0X8VA92 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/991789:CPRO_RS03600 ^@ http://purl.uniprot.org/uniprot/A0A110A7E4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9U3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS00820 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBB8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS01160 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBR3 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/991789:CPRO_RS13385 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS13815 ^@ http://purl.uniprot.org/uniprot/A0A110A7M5 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/991789:CPRO_RS12220 ^@ http://purl.uniprot.org/uniprot/A0A110A7F0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS06195 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7G2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/991789:CPRO_RS12485 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBY9 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/991789:CPRO_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A0X1U740 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/991789:CPRO_RS05905 ^@ http://purl.uniprot.org/uniprot/A0A0X1U796 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/991789:CPRO_RS00045 ^@ http://purl.uniprot.org/uniprot/A0A0X8V7M3 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/991789:CPRO_RS00950 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9D0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS04550 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS04085 ^@ http://purl.uniprot.org/uniprot/A0A110A770 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS13740 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEN2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/991789:CPRO_RS06225 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7G9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS02900 ^@ http://purl.uniprot.org/uniprot/A0A110A6Y0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/991789:CPRO_RS03505 ^@ http://purl.uniprot.org/uniprot/A0A110A6Y9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/991789:CPRO_RS12445 ^@ http://purl.uniprot.org/uniprot/A0A110A7K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS10140 ^@ http://purl.uniprot.org/uniprot/A0A120MKA3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/991789:CPRO_RS06320 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7I2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS13945 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCH0 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/991789:CPRO_RS05860 ^@ http://purl.uniprot.org/uniprot/A0A0X1U784 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/991789:CPRO_RS13280 ^@ http://purl.uniprot.org/uniprot/A0A110A7M7 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/991789:CPRO_RS02690 ^@ http://purl.uniprot.org/uniprot/A0A110A6U5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/991789:CPRO_RS13035 ^@ http://purl.uniprot.org/uniprot/A0A110A7L6 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/991789:CPRO_RS13160 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC38 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/991789:CPRO_RS12090 ^@ http://purl.uniprot.org/uniprot/A0A120MKE7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit.|||Cleaves the N-terminal amino acid of tripeptides.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS10680 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBA3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS11430 ^@ http://purl.uniprot.org/uniprot/A0A110A7S4 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS03410 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAC3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/991789:CPRO_RS10640 ^@ http://purl.uniprot.org/uniprot/A0A110A789 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS04685 ^@ http://purl.uniprot.org/uniprot/A0A110A7J2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS13135 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE41 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/991789:CPRO_RS04780 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCS7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS01250 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9G3 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/991789:CPRO_RS02010 ^@ http://purl.uniprot.org/uniprot/A0A110A6T7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/991789:CPRO_RS01670 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBU7 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/991789:CPRO_RS14740 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A110A6V1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CarB family.|||Belongs to the diaminopimelate epimerase family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS02785 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCC1 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/991789:CPRO_RS09920 ^@ http://purl.uniprot.org/uniprot/A0A110A7A5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/991789:CPRO_RS00550 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBH9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/991789:CPRO_RS08500 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8R0 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/991789:CPRO_RS11690 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBH7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/991789:CPRO_RS12355 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAM0 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/991789:CPRO_RS13840 ^@ http://purl.uniprot.org/uniprot/A0A120MKI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliR/MopE/SpaR family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS02590 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8Q2 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS10575 ^@ http://purl.uniprot.org/uniprot/A0A120MKB3 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/991789:CPRO_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCH4 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS06200 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7G7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A110A7C8 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/991789:CPRO_RS00645 ^@ http://purl.uniprot.org/uniprot/A0A0X8V994 ^@ Caution|||Similarity ^@ Belongs to the peptidase S8 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS03210 ^@ http://purl.uniprot.org/uniprot/A0A110A731 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/991789:CPRO_RS07655 ^@ http://purl.uniprot.org/uniprot/A0A0X1U883 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/991789:CPRO_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8R6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/991789:CPRO_RS01240 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBN3 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/991789:CPRO_RS01080 ^@ http://purl.uniprot.org/uniprot/A0A110A701 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/991789:CPRO_RS10055 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD46 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/991789:CPRO_RS12685 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDT6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/991789:CPRO_RS12925 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS04720 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAP7 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/991789:CPRO_RS13015 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAV4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/991789:CPRO_RS04310 ^@ http://purl.uniprot.org/uniprot/A0A120MK85 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/991789:CPRO_RS07975 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8I4 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/991789:CPRO_RS06090 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7D3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/991789:CPRO_RS11565 ^@ http://purl.uniprot.org/uniprot/A0A110A7B7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/991789:CPRO_RS09610 ^@ http://purl.uniprot.org/uniprot/A0A0X1U9E1 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/991789:CPRO_RS09850 ^@ http://purl.uniprot.org/uniprot/A0A110A751 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS03500 ^@ http://purl.uniprot.org/uniprot/A0A120MK63 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/991789:CPRO_RS11410 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDQ3 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/991789:CPRO_RS06900 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7V5 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/991789:CPRO_RS08450 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8R7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8H5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS05845 ^@ http://purl.uniprot.org/uniprot/A0A0X1U771 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS05760 ^@ http://purl.uniprot.org/uniprot/A0A0X1U774 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/991789:CPRO_RS02270 ^@ http://purl.uniprot.org/uniprot/A0A0X8VC27 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/991789:CPRO_RS14240 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS11980 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBN7 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/991789:CPRO_RS00415 ^@ http://purl.uniprot.org/uniprot/A0A0X8V984 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS00425 ^@ http://purl.uniprot.org/uniprot/A0A0X8V968 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/991789:CPRO_RS05015 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6Q8 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/991789:CPRO_RS12255 ^@ http://purl.uniprot.org/uniprot/A0A0X8VE48 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/991789:CPRO_RS07190 ^@ http://purl.uniprot.org/uniprot/A0A0X1U819 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/991789:CPRO_RS13850 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/991789:CPRO_RS12845 ^@ http://purl.uniprot.org/uniprot/A0A0X8VDZ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GdpP/PdeA phosphodiesterase family.|||Cell membrane|||For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.|||Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP). http://togogenome.org/gene/991789:CPRO_RS09885 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAT3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS01210 ^@ http://purl.uniprot.org/uniprot/A0A120MK13 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/991789:CPRO_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8Z8 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/991789:CPRO_RS00490 ^@ http://purl.uniprot.org/uniprot/A0A0X8V992 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/991789:CPRO_RS00110 ^@ http://purl.uniprot.org/uniprot/A0A0X8VB71 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS12435 ^@ http://purl.uniprot.org/uniprot/A0A110A7G2 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/991789:CPRO_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A120MK48 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/991789:CPRO_RS10730 ^@ http://purl.uniprot.org/uniprot/A0A110A7N6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/991789:CPRO_RS12215 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/991789:CPRO_RS05160 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6T6 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/991789:CPRO_RS02685 ^@ http://purl.uniprot.org/uniprot/A0A110A6W9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/991789:CPRO_RS07465 ^@ http://purl.uniprot.org/uniprot/A0A0X1U881 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/991789:CPRO_RS02990 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBU6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/991789:CPRO_RS04845 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6L8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/991789:CPRO_RS02370 ^@ http://purl.uniprot.org/uniprot/A0A110A6U0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/991789:CPRO_RS00320 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAU4 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/991789:CPRO_RS06175 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7E8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/991789:CPRO_RS01980 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9N2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS06960 ^@ http://purl.uniprot.org/uniprot/A0A0X1U7X6 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/991789:CPRO_RS05150 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6T9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS00285 ^@ http://purl.uniprot.org/uniprot/A0A0X8V7P9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/991789:CPRO_RS13265 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEF5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/991789:CPRO_RS03195 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8X4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/991789:CPRO_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A0X1U728 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS12655 ^@ http://purl.uniprot.org/uniprot/A0A110A7H6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/991789:CPRO_RS10200 ^@ http://purl.uniprot.org/uniprot/A0A120MKA9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS14415 ^@ http://purl.uniprot.org/uniprot/A0A0X8VEG2 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/991789:CPRO_RS02055 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9Q0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/991789:CPRO_RS03035 ^@ http://purl.uniprot.org/uniprot/A0A0X8V8W1 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/991789:CPRO_RS04960 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6Q2 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/991789:CPRO_RS10470 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9Y5 ^@ Similarity ^@ Belongs to the dihydropyrimidine dehydrogenase family. http://togogenome.org/gene/991789:CPRO_RS03620 ^@ http://purl.uniprot.org/uniprot/A0A0X8VAF1 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/991789:CPRO_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8I5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS12825 ^@ http://purl.uniprot.org/uniprot/A0A110A7H8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A0X8V9Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/991789:CPRO_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A0X1U6W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/991789:CPRO_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A0X1U815 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/991789:CPRO_RS07540 ^@ http://purl.uniprot.org/uniprot/A0A0X1U878 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS07785 ^@ http://purl.uniprot.org/uniprot/A0A0X1U8E2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/991789:CPRO_RS14465 ^@ http://purl.uniprot.org/uniprot/A0A110A7Y4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/991789:CPRO_RS11010 ^@ http://purl.uniprot.org/uniprot/A0A0X8VD56 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/991789:CPRO_RS05780 ^@ http://purl.uniprot.org/uniprot/A0A0X1U775 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/991789:CPRO_RS03290 ^@ http://purl.uniprot.org/uniprot/A0A120MK60 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/991789:CPRO_RS14065 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCD5 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/991789:CPRO_RS02475 ^@ http://purl.uniprot.org/uniprot/A0A0X8VBS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/991789:CPRO_RS04680 ^@ http://purl.uniprot.org/uniprot/A0A110A741 ^@ Similarity ^@ Belongs to the UPF0597 family. http://togogenome.org/gene/991789:CPRO_RS12530 ^@ http://purl.uniprot.org/uniprot/A0A110A7I2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/991789:CPRO_RS14670 ^@ http://purl.uniprot.org/uniprot/A0A0X8VCM0 ^@ Subcellular Location Annotation ^@ Membrane