http://togogenome.org/gene/1050174:CEPID_RS06130 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUD3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1050174:CEPID_RS10040 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYH1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1050174:CEPID_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLN5 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/1050174:CEPID_RS07670 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQM6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1050174:CEPID_RS04545 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS01230 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRI3 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/1050174:CEPID_RS02740 ^@ http://purl.uniprot.org/uniprot/A0A0G3GU98 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS03935 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BCCT transporter (TC 2.A.15) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS02890 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPH7 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1050174:CEPID_RS07105 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ99 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1050174:CEPID_RS08100 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSH8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1050174:CEPID_RS05235 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQV4 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/1050174:CEPID_RS07835 ^@ http://purl.uniprot.org/uniprot/A0A0G3GX71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS03820 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV15 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1050174:CEPID_RS08385 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVL7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS03900 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT33 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1050174:CEPID_RS12060 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXQ2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1050174:CEPID_RS12140 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS02205 ^@ http://purl.uniprot.org/uniprot/A0A0G3GU07 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1050174:CEPID_RS00990 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNF1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1050174:CEPID_RS01815 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRU8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS03100 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMS7 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1050174:CEPID_RS02665 ^@ http://purl.uniprot.org/uniprot/A0A0G3GU90 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/1050174:CEPID_RS06685 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/1050174:CEPID_RS08240 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVI4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS05205 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP67 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTS1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS08670 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVW4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/1050174:CEPID_RS08290 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR04 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLB7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS03515 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS10475 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS20 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1050174:CEPID_RS06730 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRR9 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/1050174:CEPID_RS00770 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS08720 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BCCT transporter (TC 2.A.15) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS07735 ^@ http://purl.uniprot.org/uniprot/A0A0G3GX58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS07485 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQB6 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1050174:CEPID_RS07635 ^@ http://purl.uniprot.org/uniprot/A0A0G3GX45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS08285 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVJ6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/1050174:CEPID_RS05050 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTN5 ^@ Similarity ^@ Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family. http://togogenome.org/gene/1050174:CEPID_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A0G3GU33 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1050174:CEPID_RS00835 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLF6 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1050174:CEPID_RS04995 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVM0 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/1050174:CEPID_RS10495 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTX7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1050174:CEPID_RS06500 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPY6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS01210 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLZ8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS06375 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPX0 ^@ Similarity ^@ Belongs to the UPF0237 family. http://togogenome.org/gene/1050174:CEPID_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1050174:CEPID_RS11555 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUN1 ^@ Similarity ^@ Belongs to the PheA/TfdB FAD monooxygenase family. http://togogenome.org/gene/1050174:CEPID_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. http://togogenome.org/gene/1050174:CEPID_RS05950 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR78 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS10015 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYG6 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/1050174:CEPID_RS06080 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWC3 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1050174:CEPID_RS04895 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS04765 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNQ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS07565 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1050174:CEPID_RS07095 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWU6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1050174:CEPID_RS02725 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMT4 ^@ Function ^@ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. http://togogenome.org/gene/1050174:CEPID_RS03020 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1050174:CEPID_RS06425 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPX6 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/1050174:CEPID_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSL0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1050174:CEPID_RS06210 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS04890 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQP7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS02385 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS04450 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS00595 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLA2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1050174:CEPID_RS11650 ^@ http://purl.uniprot.org/uniprot/A0A0G3GST0 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/1050174:CEPID_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQP0 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/1050174:CEPID_RS07915 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSD6 ^@ Similarity ^@ Belongs to the HSP15 family. http://togogenome.org/gene/1050174:CEPID_RS01495 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRN8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS03955 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNI3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1050174:CEPID_RS07435 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQA5 ^@ Similarity ^@ Belongs to the MQO family. http://togogenome.org/gene/1050174:CEPID_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A0G3GX42 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/1050174:CEPID_RS08500 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSV1 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/1050174:CEPID_RS10485 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWS7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/1050174:CEPID_RS03635 ^@ http://purl.uniprot.org/uniprot/A0A0G3GN75 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS04520 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS09575 ^@ http://purl.uniprot.org/uniprot/A0A0G3GY98 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS10060 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRT8 ^@ Caution|||Similarity ^@ Belongs to the nitrobindin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Lacks the conserved His residue that binds heme iron in the nitrobindin family. http://togogenome.org/gene/1050174:CEPID_RS09970 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWI8 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1050174:CEPID_RS06680 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRQ9 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1050174:CEPID_RS09840 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTJ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTD4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS02400 ^@ http://purl.uniprot.org/uniprot/A0A0G3GU37 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/1050174:CEPID_RS11800 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS01225 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTK5 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/1050174:CEPID_RS11080 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSK4 ^@ Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||Could possibly oxidize fatty acids using specific components. http://togogenome.org/gene/1050174:CEPID_RS03195 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPN3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1050174:CEPID_RS03845 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV20 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1050174:CEPID_RS06270 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUG6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS10330 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTT4 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/1050174:CEPID_RS07345 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS05115 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVP2 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1050174:CEPID_RS01945 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1050174:CEPID_RS11215 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZB4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS08080 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQP8 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS04465 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQG5 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1050174:CEPID_RS07960 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS00790 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLE6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS00815 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLF1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon. http://togogenome.org/gene/1050174:CEPID_RS06365 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWI1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS07405 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS40 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/1050174:CEPID_RS08645 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXV0 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/1050174:CEPID_RS08820 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS06460 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPT2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS09955 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTL3 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/1050174:CEPID_RS08125 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSI2 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1050174:CEPID_RS04290 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS10650 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSB5 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1050174:CEPID_RS05000 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTM7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/1050174:CEPID_RS11805 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZL7 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1050174:CEPID_RS04945 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVL0 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/1050174:CEPID_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A0G3GN65 ^@ Similarity ^@ Belongs to the non-flavoprotein flavin reductase family. http://togogenome.org/gene/1050174:CEPID_RS06630 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRP9 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/1050174:CEPID_RS03620 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSY4 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1050174:CEPID_RS04380 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNQ6 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1050174:CEPID_RS08900 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR90 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1050174:CEPID_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06480 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1050174:CEPID_RS09280 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRD5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS12170 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUY2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS11510 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A0G3GML4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS06505 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1050174:CEPID_RS06810 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPY8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS06700 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ18 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1050174:CEPID_RS03555 ^@ http://purl.uniprot.org/uniprot/A0A0G3GN62 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/1050174:CEPID_RS07230 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS06570 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUM8 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/1050174:CEPID_RS07995 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXA8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1050174:CEPID_RS06470 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUK7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS00700 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR42 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/1050174:CEPID_RS12325 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZU2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1050174:CEPID_RS05110 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNX4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1050174:CEPID_RS06305 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPV9 ^@ Subunit ^@ Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/1050174:CEPID_RS04860 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP02 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS11785 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXK8 ^@ Similarity ^@ Belongs to the UPF0371 family. http://togogenome.org/gene/1050174:CEPID_RS03455 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMY8 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/1050174:CEPID_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNZ2 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/1050174:CEPID_RS09585 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS07215 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRY3 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1050174:CEPID_RS06565 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWM0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/1050174:CEPID_RS12025 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSZ2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS11850 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZM3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1050174:CEPID_RS11435 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZF6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by fructose 1,6-bisphosphate (FBP).|||Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1050174:CEPID_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMC5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1050174:CEPID_RS07255 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQD1 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1050174:CEPID_RS10045 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWJ9 ^@ Similarity ^@ Belongs to the PstS family. http://togogenome.org/gene/1050174:CEPID_RS08845 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS11050 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUC9 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1050174:CEPID_RS08640 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR47 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1050174:CEPID_RS06165 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPN1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/1050174:CEPID_RS08600 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVU8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS04790 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQN1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/1050174:CEPID_RS10555 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTY9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS02265 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP66 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family. http://togogenome.org/gene/1050174:CEPID_RS06910 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ07 ^@ Similarity ^@ Belongs to the DyP-type peroxidase family. http://togogenome.org/gene/1050174:CEPID_RS03630 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ05 ^@ Similarity ^@ Belongs to the dihydrofolate reductase family. http://togogenome.org/gene/1050174:CEPID_RS07705 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQG6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/1050174:CEPID_RS10140 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS29 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/1050174:CEPID_RS04690 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNP0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1050174:CEPID_RS08620 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS05775 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS07275 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWX9 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1050174:CEPID_RS12100 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT10 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1050174:CEPID_RS02700 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMS9 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1050174:CEPID_RS11480 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1050174:CEPID_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ75 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/1050174:CEPID_RS01090 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS03545 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNC5 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1050174:CEPID_RS07300 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWY1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1050174:CEPID_RS10620 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWU4 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/1050174:CEPID_RS03520 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNC0 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/1050174:CEPID_RS01065 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRF2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS03125 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMT3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/1050174:CEPID_RS07595 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS01480 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1050174:CEPID_RS03805 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNG5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/1050174:CEPID_RS08525 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSV5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS09225 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT89 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1050174:CEPID_RS01875 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTW0 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1050174:CEPID_RS03070 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMS2 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1050174:CEPID_RS03370 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1050174:CEPID_RS07445 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV33 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1050174:CEPID_RS01295 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTL9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1050174:CEPID_RS08075 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSH3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1050174:CEPID_RS06145 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPM6 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.|||Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.|||The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group. http://togogenome.org/gene/1050174:CEPID_RS02555 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMP6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS05640 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVY0 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1050174:CEPID_RS03110 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSJ7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS02830 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSE3 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/1050174:CEPID_RS01395 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM27 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS05645 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/1050174:CEPID_RS09850 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYE1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/1050174:CEPID_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1050174:CEPID_RS08040 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1050174:CEPID_RS10960 ^@ http://purl.uniprot.org/uniprot/A0A0G3GX18 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1050174:CEPID_RS00070 ^@ http://purl.uniprot.org/uniprot/A0A0G3GST1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1050174:CEPID_RS09345 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1050174:CEPID_RS02685 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMI1 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1050174:CEPID_RS06440 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWJ7 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1050174:CEPID_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPQ9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS08810 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVZ0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS08215 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVH8 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1050174:CEPID_RS08055 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQP4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS10565 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYS1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS04250 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT99 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS06065 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPR8 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/1050174:CEPID_RS10635 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS50 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS01940 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP08 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1050174:CEPID_RS05550 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPC7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS10585 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS41 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/1050174:CEPID_RS01795 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM82 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1050174:CEPID_RS06485 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPT7 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS09870 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRQ6 ^@ Function|||Similarity ^@ Belongs to the NrdI family.|||Probably involved in ribonucleotide reductase function. http://togogenome.org/gene/1050174:CEPID_RS02085 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM57 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1050174:CEPID_RS11230 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUG4 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS08715 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A0G3GL97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06155 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUD8 ^@ Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily. http://togogenome.org/gene/1050174:CEPID_RS05370 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP97 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS11545 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXG9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class II aldolase/RraA-like family.|||Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.|||Homotrimer. http://togogenome.org/gene/1050174:CEPID_RS06740 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWQ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS01680 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNW3 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Could possibly oxidize fatty acids using specific components.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS06775 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ30 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1050174:CEPID_RS07845 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQQ9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/1050174:CEPID_RS07240 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/1050174:CEPID_RS08710 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR59 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS07580 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQD9 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/1050174:CEPID_RS02675 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMS5 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1050174:CEPID_RS10715 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYV6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTV2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1050174:CEPID_RS01820 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1050174:CEPID_RS03535 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUW5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ78 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1050174:CEPID_RS00870 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLM6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1050174:CEPID_RS07065 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ25 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1050174:CEPID_RS01170 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTJ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CobB/CobQ family. GatD subfamily.|||Forms a heterodimer with MurT.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT. http://togogenome.org/gene/1050174:CEPID_RS08860 ^@ http://purl.uniprot.org/uniprot/A0A0G3GW01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Belongs to the sulfur carrier protein TusA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS08270 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR00 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1050174:CEPID_RS01625 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM55 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/1050174:CEPID_RS01965 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP13 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/1050174:CEPID_RS06825 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ41 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1050174:CEPID_RS09925 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRR8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT24 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1050174:CEPID_RS05395 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPA2 ^@ Similarity ^@ Belongs to the helicase family. RecG subfamily. http://togogenome.org/gene/1050174:CEPID_RS04085 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNE4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS06835 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPZ3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/1050174:CEPID_RS01780 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM20 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1050174:CEPID_RS04915 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1050174:CEPID_RS07155 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS04070 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT66 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1050174:CEPID_RS01745 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/1050174:CEPID_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLX3 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1050174:CEPID_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ90 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1050174:CEPID_RS09465 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRH0 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1050174:CEPID_RS01590 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTS2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/1050174:CEPID_RS06295 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWG6 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/1050174:CEPID_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A0G3GND9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS04970 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVL3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS09890 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS07075 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUV6 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRX8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS03915 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNB4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS10460 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWS4 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/1050174:CEPID_RS04230 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNM6 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/1050174:CEPID_RS07250 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUZ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS11560 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM175 family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06370 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS09325 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTB0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS05285 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQW6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS06985 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRW5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQZ7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1050174:CEPID_RS06075 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPL6 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/1050174:CEPID_RS05585 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP68 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1050174:CEPID_RS01980 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS10260 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS01615 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTS5 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/1050174:CEPID_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVV7 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1050174:CEPID_RS11670 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUQ1 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS11410 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZF1 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1050174:CEPID_RS10235 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS10975 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSE6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1050174:CEPID_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM46 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1050174:CEPID_RS06510 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPU2 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS00830 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNB6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1050174:CEPID_RS10900 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSC9 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1050174:CEPID_RS06545 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUM2 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1050174:CEPID_RS05350 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQX6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1050174:CEPID_RS08550 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVU0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1050174:CEPID_RS08935 ^@ http://purl.uniprot.org/uniprot/A0A0G3GW15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06560 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPV0 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1050174:CEPID_RS08895 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS03960 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ65 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/1050174:CEPID_RS10175 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRW2 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1050174:CEPID_RS03420 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS08060 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXC7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS12155 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZQ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1050174:CEPID_RS02045 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRZ1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS06620 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1050174:CEPID_RS03575 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPZ9 ^@ Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||Could possibly oxidize fatty acids using specific components. http://togogenome.org/gene/1050174:CEPID_RS10945 ^@ http://purl.uniprot.org/uniprot/A0A0G3GU62 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1050174:CEPID_RS00410 ^@ http://purl.uniprot.org/uniprot/A0A0G3GN47 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1050174:CEPID_RS03375 ^@ http://purl.uniprot.org/uniprot/A0A0G3GN49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1050174:CEPID_RS09920 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06325 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUH6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS03690 ^@ http://purl.uniprot.org/uniprot/A0A0G3GN82 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1050174:CEPID_RS08025 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQV0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1050174:CEPID_RS08205 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with subunits I, II and III to form cytochrome c oxidase.|||Belongs to the cytochrome c oxidase bacterial subunit CtaF family.|||Cell membrane|||Membrane|||Part of cytochrome c oxidase, its function is unknown. http://togogenome.org/gene/1050174:CEPID_RS05280 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP82 ^@ Similarity ^@ Belongs to the isochorismate synthase family. http://togogenome.org/gene/1050174:CEPID_RS08780 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXX6 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/1050174:CEPID_RS10670 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWV3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS10245 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS42 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1050174:CEPID_RS09415 ^@ http://purl.uniprot.org/uniprot/A0A0G3GW94 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1050174:CEPID_RS07620 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQL6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/1050174:CEPID_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNF7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1050174:CEPID_RS05790 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS06430 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRK8 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/1050174:CEPID_RS05020 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVM4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS06635 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPW2 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS04705 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06895 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUT5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.|||Cell membrane|||Contains a di-nuclear catalytic Mg(2+) center.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06750 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ26 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS06235 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPP3 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/1050174:CEPID_RS12275 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZT1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1050174:CEPID_RS10875 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSC2 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/1050174:CEPID_RS06265 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWG2 ^@ Similarity ^@ Belongs to the UPF0098 family. http://togogenome.org/gene/1050174:CEPID_RS07495 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06650 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ08 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1050174:CEPID_RS02305 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS38 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1050174:CEPID_RS04865 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQP3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1050174:CEPID_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS05415 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06860 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPZ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/1050174:CEPID_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMH0 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/1050174:CEPID_RS01195 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLS1 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUH0 ^@ Subunit ^@ Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/1050174:CEPID_RS01185 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS03550 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPZ4 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1050174:CEPID_RS05885 ^@ http://purl.uniprot.org/uniprot/A0A0G3GW36 ^@ Similarity ^@ Belongs to the UPF0225 family. http://togogenome.org/gene/1050174:CEPID_RS04350 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1050174:CEPID_RS05980 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPE4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS12595 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT39 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/1050174:CEPID_RS12095 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS10735 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS68 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1050174:CEPID_RS09030 ^@ http://purl.uniprot.org/uniprot/A0A0G3GW32 ^@ Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/1050174:CEPID_RS07305 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV03 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS04600 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1050174:CEPID_RS03930 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Belongs to the precorrin methyltransferase family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS02975 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUE7 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/1050174:CEPID_RS01350 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNQ2 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1050174:CEPID_RS09775 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRW3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1050174:CEPID_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS89 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1050174:CEPID_RS10710 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III. http://togogenome.org/gene/1050174:CEPID_RS00405 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLE2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1050174:CEPID_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSI6 ^@ Cofactor|||Similarity ^@ Belongs to the class-II DAHP synthase family.|||Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions. http://togogenome.org/gene/1050174:CEPID_RS04910 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP11 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1050174:CEPID_RS10990 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS07805 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQI8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1050174:CEPID_RS04870 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNS5 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1050174:CEPID_RS10300 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS00425 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQY7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1050174:CEPID_RS02335 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMK0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1050174:CEPID_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQB1 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1050174:CEPID_RS03815 ^@ http://purl.uniprot.org/uniprot/A0A0G3GN99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/1050174:CEPID_RS03080 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSJ3 ^@ Cofactor|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1050174:CEPID_RS06150 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWE0 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic ubiquitin-like protein family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.|||Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.|||The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome. http://togogenome.org/gene/1050174:CEPID_RS10420 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS06865 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWS2 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/1050174:CEPID_RS04370 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVB5 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/1050174:CEPID_RS07140 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ42 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1050174:CEPID_RS02655 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPD4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS12585 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZM9 ^@ Caution|||Similarity ^@ Belongs to the peptidase S8 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTA4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/1050174:CEPID_RS06830 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS02075 ^@ http://purl.uniprot.org/uniprot/A0A0G3GME5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1050174:CEPID_RS08665 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR51 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/1050174:CEPID_RS05795 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR54 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1050174:CEPID_RS09330 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRE4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSU7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS01315 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRK3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1050174:CEPID_RS10180 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYJ3 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/1050174:CEPID_RS02570 ^@ http://purl.uniprot.org/uniprot/A0A0G3GU79 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/1050174:CEPID_RS07690 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS08370 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSM5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS03590 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS05355 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP19 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1050174:CEPID_RS11665 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSX5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1050174:CEPID_RS11855 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXM2 ^@ Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||Could possibly oxidize fatty acids using specific components. http://togogenome.org/gene/1050174:CEPID_RS02500 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. DnaE2 subfamily.|||Cytoplasm|||DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. http://togogenome.org/gene/1050174:CEPID_RS10480 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS12270 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS10695 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWV8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS07130 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/1050174:CEPID_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXT0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Acyl carrier protein involved in meromycolate extension.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A0G3GW72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS05715 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPF6 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/1050174:CEPID_RS01865 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNZ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1050174:CEPID_RS02930 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSG8 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1050174:CEPID_RS04220 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV91 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.|||Belongs to the MshB deacetylase family. Mca subfamily.|||Binds 1 zinc ion per subunit.|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS10380 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTU4 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/1050174:CEPID_RS06590 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWM5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS05185 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQU6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1050174:CEPID_RS10820 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS06380 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRJ9 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS08065 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVE5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS00670 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT42 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1050174:CEPID_RS07145 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWV4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06205 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPU4 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/1050174:CEPID_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNG8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1050174:CEPID_RS09750 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRV6 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/1050174:CEPID_RS11530 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUM5 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1050174:CEPID_RS10470 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTX0 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/1050174:CEPID_RS11255 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUG8 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/1050174:CEPID_RS10345 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWQ6 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/1050174:CEPID_RS09780 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTI3 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1050174:CEPID_RS03040 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPK5 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1050174:CEPID_RS01280 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM13 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1050174:CEPID_RS05070 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTP0 ^@ Function|||Similarity|||Subunit ^@ Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.|||Belongs to the AhpD family.|||Homotrimer. http://togogenome.org/gene/1050174:CEPID_RS07975 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVD3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1050174:CEPID_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUE2 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/1050174:CEPID_RS11895 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSW7 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/1050174:CEPID_RS01870 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM31 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1050174:CEPID_RS04065 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1050174:CEPID_RS00780 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS10630 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS05015 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNV5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiN family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/1050174:CEPID_RS01255 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS08925 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR93 ^@ Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. http://togogenome.org/gene/1050174:CEPID_RS09835 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRX3 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1050174:CEPID_RS10025 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1050174:CEPID_RS03480 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMZ5 ^@ Similarity ^@ Belongs to the transglycosylase family. Rpf subfamily. http://togogenome.org/gene/1050174:CEPID_RS10535 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTY5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/1050174:CEPID_RS07600 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS74 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1050174:CEPID_RS00665 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLB9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1050174:CEPID_RS04010 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS05240 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP00 ^@ Similarity ^@ Belongs to the non-flavoprotein flavin reductase family. http://togogenome.org/gene/1050174:CEPID_RS10860 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWZ5 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/1050174:CEPID_RS10240 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWN6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the diaminopimelate dehydrogenase family.|||Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVT0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS02270 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM95 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/1050174:CEPID_RS06645 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUP4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/1050174:CEPID_RS02545 ^@ http://purl.uniprot.org/uniprot/A0A0G3GU72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS05195 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVQ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS06990 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ14 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/1050174:CEPID_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A0G3GML5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1050174:CEPID_RS07590 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV63 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/1050174:CEPID_RS12395 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMH6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS07650 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS83 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1050174:CEPID_RS05970 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPJ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS08250 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSK1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1050174:CEPID_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVB2 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS04050 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNJ5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS09685 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRM2 ^@ Function ^@ Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). http://togogenome.org/gene/1050174:CEPID_RS05410 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVS8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1050174:CEPID_RS05615 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVX5 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1050174:CEPID_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVY1 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1050174:CEPID_RS11635 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZI8 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1050174:CEPID_RS08190 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVH2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Cell membrane|||Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis. http://togogenome.org/gene/1050174:CEPID_RS11505 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUM1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1050174:CEPID_RS11790 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT01 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS05010 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQR5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiM family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Membrane|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/1050174:CEPID_RS02805 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUA9 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/1050174:CEPID_RS11770 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUR7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS11960 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXN7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HsdR family.|||Subunit R is required for both nuclease and ATPase activities, but not for modification.|||The type I restriction/modification system is composed of three polypeptides R, M and S. http://togogenome.org/gene/1050174:CEPID_RS02000 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTY0 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1050174:CEPID_RS05055 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP40 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPN9 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. http://togogenome.org/gene/1050174:CEPID_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP59 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS04610 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQJ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS09300 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/1050174:CEPID_RS05680 ^@ http://purl.uniprot.org/uniprot/A0A0G3GU03 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/1050174:CEPID_RS05785 ^@ http://purl.uniprot.org/uniprot/A0A0G3GU19 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1050174:CEPID_RS10365 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYM0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DisA family.|||Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.|||Homooctamer.|||Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. http://togogenome.org/gene/1050174:CEPID_RS03735 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ22 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/1050174:CEPID_RS04390 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTC5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediates zinc uptake. May also transport other divalent cations.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS10610 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS09405 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRF8 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/1050174:CEPID_RS08180 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQR4 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1050174:CEPID_RS12180 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZR1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1050174:CEPID_RS02965 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPJ0 ^@ Similarity ^@ Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/1050174:CEPID_RS01205 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRH8 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/1050174:CEPID_RS06260 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPP7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS07385 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS36 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS04075 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNJ9 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/1050174:CEPID_RS09245 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRL1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS08625 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVV1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1050174:CEPID_RS04920 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1050174:CEPID_RS11730 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZK5 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/1050174:CEPID_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS46 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1050174:CEPID_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWB3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS09505 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRR1 ^@ Similarity ^@ Belongs to the truncated hemoglobin family. Group II subfamily. http://togogenome.org/gene/1050174:CEPID_RS09720 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWE4 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1050174:CEPID_RS01755 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM16 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1050174:CEPID_RS02040 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTY7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1050174:CEPID_RS01850 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTV8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1050174:CEPID_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMX6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1050174:CEPID_RS06675 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ12 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1050174:CEPID_RS05985 ^@ http://purl.uniprot.org/uniprot/A0A0G3GW58 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1050174:CEPID_RS04570 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVE0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/1050174:CEPID_RS01880 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRW1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1050174:CEPID_RS04235 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQB7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS01720 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRT0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1050174:CEPID_RS00245 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS09065 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT58 ^@ Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase class-III family. http://togogenome.org/gene/1050174:CEPID_RS08460 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVN4 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1050174:CEPID_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPD6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS22 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1050174:CEPID_RS12185 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXS2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1050174:CEPID_RS03415 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS11095 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSQ3 ^@ Similarity ^@ Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family. http://togogenome.org/gene/1050174:CEPID_RS07855 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQJ9 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1050174:CEPID_RS00575 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS03470 ^@ http://purl.uniprot.org/uniprot/A0A0G3GN63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS01775 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNX7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1050174:CEPID_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNU5 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1050174:CEPID_RS09740 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYB9 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1050174:CEPID_RS06575 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPZ6 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/1050174:CEPID_RS09680 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTG4 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/1050174:CEPID_RS07895 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQS0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1050174:CEPID_RS01150 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRG9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1050174:CEPID_RS07540 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV52 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS06745 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS02485 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1050174:CEPID_RS01330 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS09670 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWD5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS05935 ^@ http://purl.uniprot.org/uniprot/A0A0G3GW46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS02340 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP80 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1050174:CEPID_RS09190 ^@ http://purl.uniprot.org/uniprot/A0A0G3GY44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1050174:CEPID_RS04900 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS01175 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRH4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/1050174:CEPID_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMR8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS09425 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTC8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1050174:CEPID_RS10225 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTR3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS09710 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1050174:CEPID_RS05340 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTU0 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-66 and Arg-69) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. http://togogenome.org/gene/1050174:CEPID_RS10575 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS07225 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/1050174:CEPID_RS06805 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRT4 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1050174:CEPID_RS04805 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTJ0 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/1050174:CEPID_RS03180 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUI8 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/1050174:CEPID_RS06355 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRJ4 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/1050174:CEPID_RS07750 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSA0 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1050174:CEPID_RS10525 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS28 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/1050174:CEPID_RS01990 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP17 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1050174:CEPID_RS03755 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNF9 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/1050174:CEPID_RS11490 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS04905 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1050174:CEPID_RS08615 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS05625 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPE1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS02050 ^@ http://purl.uniprot.org/uniprot/A0A0G3GME0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1050174:CEPID_RS11280 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUH4 ^@ Similarity ^@ Belongs to the mycobacterial A85 antigen family. http://togogenome.org/gene/1050174:CEPID_RS07310 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQE2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/1050174:CEPID_RS10425 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS10 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS02945 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMP5 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/1050174:CEPID_RS02320 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMA6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/1050174:CEPID_RS04680 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP23 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/1050174:CEPID_RS04280 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNN6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSA9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPB7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS12300 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZT6 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/1050174:CEPID_RS04940 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNU2 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/1050174:CEPID_RS00855 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLG1 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/1050174:CEPID_RS02515 ^@ http://purl.uniprot.org/uniprot/A0A0G3GME6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS02060 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM54 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1050174:CEPID_RS12235 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXT2 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/1050174:CEPID_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A0G3GKY0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1050174:CEPID_RS10035 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRT3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1050174:CEPID_RS01460 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLW6 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/1050174:CEPID_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP79 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS07815 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS07720 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQN5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS01760 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTU8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1050174:CEPID_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPD5 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/1050174:CEPID_RS07370 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWZ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1050174:CEPID_RS04355 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1050174:CEPID_RS08095 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1050174:CEPID_RS00030 ^@ http://purl.uniprot.org/uniprot/A0A0G3GL71 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1050174:CEPID_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM85 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1050174:CEPID_RS00825 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLL6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS01445 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRM9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1050174:CEPID_RS02010 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMD0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1050174:CEPID_RS07570 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQK3 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/1050174:CEPID_RS06720 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUQ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS01805 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM23 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1050174:CEPID_RS08245 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQZ5 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1050174:CEPID_RS00435 ^@ http://purl.uniprot.org/uniprot/A0A0G3GN50 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS00050 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS09440 ^@ http://purl.uniprot.org/uniprot/A0A0G3GW99 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1050174:CEPID_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP98 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1050174:CEPID_RS07280 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS03940 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNB7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS09875 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYE6 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/1050174:CEPID_RS10340 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYL5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS06655 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRQ4 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/1050174:CEPID_RS04795 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNQ8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS08755 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXX0 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1050174:CEPID_RS03825 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT20 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1050174:CEPID_RS00385 ^@ http://purl.uniprot.org/uniprot/A0A0G3GN43 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/1050174:CEPID_RS06585 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPV4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS09080 ^@ http://purl.uniprot.org/uniprot/A0A0G3GW42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1050174:CEPID_RS02905 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSG4 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1050174:CEPID_RS09725 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRV1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1050174:CEPID_RS08145 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS10560 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS04310 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQD0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/1050174:CEPID_RS02980 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSH6 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/1050174:CEPID_RS09340 ^@ http://purl.uniprot.org/uniprot/A0A0G3GW84 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1050174:CEPID_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A0G3GL90 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1050174:CEPID_RS10745 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWX0 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1050174:CEPID_RS01660 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/1050174:CEPID_RS04480 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTE1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS03330 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPQ6 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/1050174:CEPID_RS07220 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS08235 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXG8 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/1050174:CEPID_RS06475 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPY2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS01085 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS06725 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ21 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS06580 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRN9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1050174:CEPID_RS06320 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWH2 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1050174:CEPID_RS11245 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXB6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS02970 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMQ0 ^@ Caution|||Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS09885 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRY6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1050174:CEPID_RS08030 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSG3 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1050174:CEPID_RS03130 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1050174:CEPID_RS06170 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWE3 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/1050174:CEPID_RS09570 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRJ3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1050174:CEPID_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVW3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1050174:CEPID_RS01690 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTT8 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/1050174:CEPID_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMX3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/1050174:CEPID_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNK0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the MshB deacetylase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. http://togogenome.org/gene/1050174:CEPID_RS01640 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS09395 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRP0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1050174:CEPID_RS08680 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSY3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/1050174:CEPID_RS09230 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRC8 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/1050174:CEPID_RS08585 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS05160 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQU0 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1050174:CEPID_RS03790 ^@ http://purl.uniprot.org/uniprot/A0A0G3GN95 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/1050174:CEPID_RS11160 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSL5 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/1050174:CEPID_RS02610 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPC6 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/1050174:CEPID_RS02110 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS03055 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSI9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1050174:CEPID_RS04325 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTB1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/1050174:CEPID_RS01860 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM98 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1050174:CEPID_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRD3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS07875 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSC5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS05200 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06970 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ11 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ChdC family. Type 2 subfamily.|||Fe-coproporphyrin III acts as both substrate and redox cofactor.|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate. http://togogenome.org/gene/1050174:CEPID_RS11515 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZH0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1050174:CEPID_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTE4 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1050174:CEPID_RS11630 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSS7 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1050174:CEPID_RS05610 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP73 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1050174:CEPID_RS02550 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS85 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS07820 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQQ5 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1050174:CEPID_RS09430 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRG5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1050174:CEPID_RS02835 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMV5 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/1050174:CEPID_RS06615 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1050174:CEPID_RS12315 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1050174:CEPID_RS01245 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS03580 ^@ http://purl.uniprot.org/uniprot/A0A0G3GN67 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1050174:CEPID_RS07555 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQD4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1050174:CEPID_RS11240 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZB9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 85 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS08070 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06695 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUQ3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS05945 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS06160 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPT6 ^@ Similarity|||Subunit ^@ Belongs to the AAA ATPase family.|||Homohexamer. Assembles into a hexameric ring structure. http://togogenome.org/gene/1050174:CEPID_RS09305 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRD9 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1050174:CEPID_RS10675 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS03765 ^@ http://purl.uniprot.org/uniprot/A0A0G3GN91 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1050174:CEPID_RS08260 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXH5 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1050174:CEPID_RS01095 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRG0 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/1050174:CEPID_RS01250 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS09730 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1050174:CEPID_RS10150 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS10840 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS07630 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1050174:CEPID_RS07500 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQI6 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS09705 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS09485 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTD5 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1050174:CEPID_RS10600 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSA3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1050174:CEPID_RS06855 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS05650 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPE5 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS07460 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQA9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1050174:CEPID_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNA3 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/1050174:CEPID_RS06535 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPU6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1050174:CEPID_RS10020 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWJ3 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1050174:CEPID_RS09520 ^@ http://purl.uniprot.org/uniprot/A0A0G3GY92 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/1050174:CEPID_RS09200 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS05030 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP35 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. http://togogenome.org/gene/1050174:CEPID_RS11495 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXF9 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1050174:CEPID_RS12040 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT54 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/1050174:CEPID_RS11995 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUV1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/1050174:CEPID_RS07615 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV68 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1050174:CEPID_RS11745 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUR2 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/1050174:CEPID_RS01845 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNY9 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1050174:CEPID_RS00130 ^@ http://purl.uniprot.org/uniprot/A0A0G3GST8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS12280 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXU0 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS01515 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTQ8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/1050174:CEPID_RS08120 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQX1 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1050174:CEPID_RS06185 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1050174:CEPID_RS12070 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUW4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS10760 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS75 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1050174:CEPID_RS07530 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS02495 ^@ http://purl.uniprot.org/uniprot/A0A0G3GU61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS10955 ^@ http://purl.uniprot.org/uniprot/A0A0G3GZ13 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1050174:CEPID_RS07710 ^@ http://purl.uniprot.org/uniprot/A0A0G3GX55 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/1050174:CEPID_RS00110 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQT2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS06690 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWP5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS10280 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTS3 ^@ Function|||Similarity ^@ Belongs to the trehalose phosphatase family.|||Removes the phosphate from trehalose 6-phosphate to produce free trehalose. http://togogenome.org/gene/1050174:CEPID_RS05655 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS05630 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR25 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/1050174:CEPID_RS01900 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTW4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1050174:CEPID_RS06705 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRR4 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/1050174:CEPID_RS09965 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYG1 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1050174:CEPID_RS06495 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUL2 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/1050174:CEPID_RS04140 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNF2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1050174:CEPID_RS08700 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRB7 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/1050174:CEPID_RS11330 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSP1 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/1050174:CEPID_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS02380 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS51 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/1050174:CEPID_RS00190 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrgA family.|||Cell membrane|||Involved in cell division. http://togogenome.org/gene/1050174:CEPID_RS03810 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ37 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/1050174:CEPID_RS06220 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUF5 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/1050174:CEPID_RS01750 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNX2 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1050174:CEPID_RS12265 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV02 ^@ Similarity ^@ Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family. http://togogenome.org/gene/1050174:CEPID_RS05685 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS03705 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNF0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS06100 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWC9 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1050174:CEPID_RS04925 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVK5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1050174:CEPID_RS01695 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRS8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family. MenD subfamily.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS06245 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUG1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.|||Monomer. http://togogenome.org/gene/1050174:CEPID_RS10375 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS60 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/1050174:CEPID_RS06905 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRV5 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS04800 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVI1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1050174:CEPID_RS11430 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSQ5 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1050174:CEPID_RS11090 ^@ http://purl.uniprot.org/uniprot/A0A0G3GX87 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1050174:CEPID_RS06515 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS00600 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT27 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS00450 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM80 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1050174:CEPID_RS05580 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR15 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1050174:CEPID_RS07685 ^@ http://purl.uniprot.org/uniprot/A0A0G3GX52 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1050174:CEPID_RS06225 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS08635 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSX2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1050174:CEPID_RS11700 ^@ http://purl.uniprot.org/uniprot/A0A0G3GST6 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/1050174:CEPID_RS02300 ^@ http://purl.uniprot.org/uniprot/A0A0G3GU21 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein bS18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS08155 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQR0 ^@ Cofactor|||Function|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS01890 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNZ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1050174:CEPID_RS06660 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPW7 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/1050174:CEPID_RS02645 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSA2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1050174:CEPID_RS01550 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM45 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1050174:CEPID_RS01895 ^@ http://purl.uniprot.org/uniprot/A0A0G3GM34 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1050174:CEPID_RS06840 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWR9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/1050174:CEPID_RS10465 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS78 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/1050174:CEPID_RS10085 ^@ http://purl.uniprot.org/uniprot/A0A0G3GYH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS08890 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRE5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit.|||Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes. http://togogenome.org/gene/1050174:CEPID_RS02800 ^@ http://purl.uniprot.org/uniprot/A0A0G3GML0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS01885 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMA4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1050174:CEPID_RS00125 ^@ http://purl.uniprot.org/uniprot/A0A0G3GL00 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1050174:CEPID_RS06465 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS08320 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSL6 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1050174:CEPID_RS03785 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ32 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/1050174:CEPID_RS08230 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQS3 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/1050174:CEPID_RS05535 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP56 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1050174:CEPID_RS09620 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWC5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/1050174:CEPID_RS07295 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQ73 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/1050174:CEPID_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR40 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS06870 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUT1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS00585 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS05995 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS02360 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMK4 ^@ Similarity ^@ Belongs to the IMPDH/GMPR family. http://togogenome.org/gene/1050174:CEPID_RS07545 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQJ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS08405 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXK9 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1050174:CEPID_RS04975 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTM1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.|||Homodimer.|||Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. http://togogenome.org/gene/1050174:CEPID_RS06000 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR86 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS04935 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP16 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NucS endonuclease family.|||Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS07355 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1050174:CEPID_RS00725 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR48 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/1050174:CEPID_RS02985 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMY3 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/1050174:CEPID_RS06595 ^@ http://purl.uniprot.org/uniprot/A0A0G3GUN3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS01855 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRV7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1050174:CEPID_RS01220 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLS5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1050174:CEPID_RS07070 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWU3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1050174:CEPID_RS07535 ^@ http://purl.uniprot.org/uniprot/A0A0G3GX32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1050174:CEPID_RS08750 ^@ http://purl.uniprot.org/uniprot/A0A0G3GR66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS00095 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMZ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS11535 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSR9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1050174:CEPID_RS02580 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS07990 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQM9 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/1050174:CEPID_RS08690 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXW0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IPP isomerase type 1 family.|||Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).|||Cytoplasm http://togogenome.org/gene/1050174:CEPID_RS09380 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRF3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/1050174:CEPID_RS03880 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS03010 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMY9 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/1050174:CEPID_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS97 ^@ Cofactor|||Similarity ^@ Belongs to the monomeric-type IDH family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/1050174:CEPID_RS06610 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPV8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS08275 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSK6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1050174:CEPID_RS09910 ^@ http://purl.uniprot.org/uniprot/A0A0G3GWH9 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A0G3GXG2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/1050174:CEPID_RS10360 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRZ7 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1050174:CEPID_RS05780 ^@ http://purl.uniprot.org/uniprot/A0A0G3GW12 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS03925 ^@ http://purl.uniprot.org/uniprot/A0A0G3GT38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 39 family.|||Cell membrane|||Membrane|||Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. http://togogenome.org/gene/1050174:CEPID_RS02505 ^@ http://purl.uniprot.org/uniprot/A0A0G3GMN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1050174:CEPID_RS02990 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HupC/HyaC/HydC family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS07755 ^@ http://purl.uniprot.org/uniprot/A0A0G3GQH6 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/1050174:CEPID_RS08885 ^@ http://purl.uniprot.org/uniprot/A0A0G3GW05 ^@ Function|||Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||May catalyze the transamination reaction in phenylalanine biosynthesis. http://togogenome.org/gene/1050174:CEPID_RS05620 ^@ http://purl.uniprot.org/uniprot/A0A0G3GTZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/1050174:CEPID_RS07480 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS53 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1050174:CEPID_RS11055 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSK0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1050174:CEPID_RS06605 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRP3 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1050174:CEPID_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLY8 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1050174:CEPID_RS09915 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRZ2 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1050174:CEPID_RS08265 ^@ http://purl.uniprot.org/uniprot/A0A0G3GVJ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1050174:CEPID_RS00105 ^@ http://purl.uniprot.org/uniprot/A0A0G3GST4 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/1050174:CEPID_RS02080 ^@ http://purl.uniprot.org/uniprot/A0A0G3GP32 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1050174:CEPID_RS04340 ^@ http://purl.uniprot.org/uniprot/A0A0G3GNH8 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1050174:CEPID_RS08445 ^@ http://purl.uniprot.org/uniprot/A0A0G3GSN9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1050174:CEPID_RS02070 ^@ http://purl.uniprot.org/uniprot/A0A0G3GRZ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1050174:CEPID_RS03995 ^@ http://purl.uniprot.org/uniprot/A0A0G3GV47 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/1050174:CEPID_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A0G3GLX8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1050174:CEPID_RS05895 ^@ http://purl.uniprot.org/uniprot/A0A0G3GPI7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1050174:CEPID_RS07455 ^@ http://purl.uniprot.org/uniprot/A0A0G3GS48 ^@ Caution|||Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.|||Lacks conserved residue(s) required for the propagation of feature annotation.