http://togogenome.org/gene/1121448:DGI_RS06760 ^@ http://purl.uniprot.org/uniprot/T2GBI9 ^@ Cofactor ^@ Binds 4 heme c groups covalently per monomer. http://togogenome.org/gene/1121448:DGI_RS06745 ^@ http://purl.uniprot.org/uniprot/T2GAS0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1121448:DGI_RS08870 ^@ http://purl.uniprot.org/uniprot/T2GAU2 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS15115 ^@ http://purl.uniprot.org/uniprot/T2GFN8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1121448:DGI_RS11245 ^@ http://purl.uniprot.org/uniprot/T2GDD9 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/1121448:DGI_RS09495 ^@ http://purl.uniprot.org/uniprot/T2GBZ0 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/1121448:DGI_RS13840 ^@ http://purl.uniprot.org/uniprot/T2GEK4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1121448:DGI_RS06560 ^@ http://purl.uniprot.org/uniprot/T2GAT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS01785 ^@ http://purl.uniprot.org/uniprot/T2G7M8 ^@ Subunit ^@ Heterodimer of a large and a small subunit. http://togogenome.org/gene/1121448:DGI_RS01740 ^@ http://purl.uniprot.org/uniprot/T2G7X6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1121448:DGI_RS01615 ^@ http://purl.uniprot.org/uniprot/T2G6Q6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1121448:DGI_RS03480 ^@ http://purl.uniprot.org/uniprot/T2G8M6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1121448:DGI_RS06365 ^@ http://purl.uniprot.org/uniprot/T2GBB6 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/1121448:DGI_RS10085 ^@ http://purl.uniprot.org/uniprot/T2GCV1 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS01000 ^@ http://purl.uniprot.org/uniprot/T2G8D8 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/1121448:DGI_RS11725 ^@ http://purl.uniprot.org/uniprot/T2GCH8 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/1121448:DGI_RS07135 ^@ http://purl.uniprot.org/uniprot/T2GAN6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/1121448:DGI_RS09870 ^@ http://purl.uniprot.org/uniprot/T2GCK6 ^@ Similarity ^@ Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/1121448:DGI_RS15885 ^@ http://purl.uniprot.org/uniprot/T2GG32 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS10665 ^@ http://purl.uniprot.org/uniprot/T2GCR8 ^@ Similarity ^@ Belongs to the pyruvoyl-dependent arginine decarboxylase family. http://togogenome.org/gene/1121448:DGI_RS01425 ^@ http://purl.uniprot.org/uniprot/T2G7R2 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/1121448:DGI_RS13455 ^@ http://purl.uniprot.org/uniprot/T2GFG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS14630 ^@ http://purl.uniprot.org/uniprot/T2GE47 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/1121448:DGI_RS07180 ^@ http://purl.uniprot.org/uniprot/T2GBR5 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/1121448:DGI_RS08740 ^@ http://purl.uniprot.org/uniprot/T2GBX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1121448:DGI_RS12105 ^@ http://purl.uniprot.org/uniprot/T2GEK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS11510 ^@ http://purl.uniprot.org/uniprot/T2GCD6 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1121448:DGI_RS06370 ^@ http://purl.uniprot.org/uniprot/T2GA89 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1121448:DGI_RS12420 ^@ http://purl.uniprot.org/uniprot/T2GE69 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1121448:DGI_RS08210 ^@ http://purl.uniprot.org/uniprot/T2GBC2 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1121448:DGI_RS04215 ^@ http://purl.uniprot.org/uniprot/T2G9C2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS00910 ^@ http://purl.uniprot.org/uniprot/T2G6D9 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1121448:DGI_RS07200 ^@ http://purl.uniprot.org/uniprot/T2GBR9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1121448:DGI_RS04205 ^@ http://purl.uniprot.org/uniprot/T2GA35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/1121448:DGI_RS10035 ^@ http://purl.uniprot.org/uniprot/T2GCU0 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1121448:DGI_RS06540 ^@ http://purl.uniprot.org/uniprot/T2GBE9 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/1121448:DGI_RS04195 ^@ http://purl.uniprot.org/uniprot/T2G855 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1121448:DGI_RS07485 ^@ http://purl.uniprot.org/uniprot/T2G9Z8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/1121448:DGI_RS07550 ^@ http://purl.uniprot.org/uniprot/T2GAW9 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/1121448:DGI_RS16030 ^@ http://purl.uniprot.org/uniprot/T2GF07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/1121448:DGI_RS09210 ^@ http://purl.uniprot.org/uniprot/T2GB03 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1121448:DGI_RS05235 ^@ http://purl.uniprot.org/uniprot/T2G9K3 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1121448:DGI_RS08890 ^@ http://purl.uniprot.org/uniprot/T2GC00 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1121448:DGI_RS14525 ^@ http://purl.uniprot.org/uniprot/T2GEX9 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1121448:DGI_RS09730 ^@ http://purl.uniprot.org/uniprot/T2GCN1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS14475 ^@ http://purl.uniprot.org/uniprot/T2GEW9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1121448:DGI_RS14185 ^@ http://purl.uniprot.org/uniprot/T2GFS2 ^@ Similarity ^@ Belongs to the ATPase alpha/beta chains family. http://togogenome.org/gene/1121448:DGI_RS14925 ^@ http://purl.uniprot.org/uniprot/T2GFK9 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1121448:DGI_RS15720 ^@ http://purl.uniprot.org/uniprot/T2GGE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS06580 ^@ http://purl.uniprot.org/uniprot/T2G9H2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS07540 ^@ http://purl.uniprot.org/uniprot/T2GBC6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1121448:DGI_RS17280 ^@ http://purl.uniprot.org/uniprot/T2GDY3 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/1121448:DGI_RS08055 ^@ http://purl.uniprot.org/uniprot/T2GBJ3 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/1121448:DGI_RS00520 ^@ http://purl.uniprot.org/uniprot/T2G653 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1121448:DGI_RS08200 ^@ http://purl.uniprot.org/uniprot/T2GBT3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1121448:DGI_RS11865 ^@ http://purl.uniprot.org/uniprot/T2GDC0 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/1121448:DGI_RS06565 ^@ http://purl.uniprot.org/uniprot/T2GBF4 ^@ Similarity ^@ Belongs to the Ahb/Nir family. http://togogenome.org/gene/1121448:DGI_RS09760 ^@ http://purl.uniprot.org/uniprot/T2GCN5 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1121448:DGI_RS15850 ^@ http://purl.uniprot.org/uniprot/T2GFY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS01405 ^@ http://purl.uniprot.org/uniprot/T2G8K6 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1121448:DGI_RS13100 ^@ http://purl.uniprot.org/uniprot/T2GEN4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1121448:DGI_RS06885 ^@ http://purl.uniprot.org/uniprot/T2GBL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS08835 ^@ http://purl.uniprot.org/uniprot/T2GBM4 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1121448:DGI_RS07470 ^@ http://purl.uniprot.org/uniprot/T2GBX4 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily. http://togogenome.org/gene/1121448:DGI_RS15700 ^@ http://purl.uniprot.org/uniprot/T2GFN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/1121448:DGI_RS12565 ^@ http://purl.uniprot.org/uniprot/T2GE45 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS02495 ^@ http://purl.uniprot.org/uniprot/T2G943 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutC family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/1121448:DGI_RS14080 ^@ http://purl.uniprot.org/uniprot/T2GF63 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS09635 ^@ http://purl.uniprot.org/uniprot/T2GD70 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1121448:DGI_RS10365 ^@ http://purl.uniprot.org/uniprot/T2GCW1 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/1121448:DGI_RS11910 ^@ http://purl.uniprot.org/uniprot/T2GDD1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS09765 ^@ http://purl.uniprot.org/uniprot/T2GD93 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1121448:DGI_RS07330 ^@ http://purl.uniprot.org/uniprot/T2GBU4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1121448:DGI_RS13625 ^@ http://purl.uniprot.org/uniprot/T2GES5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS01735 ^@ http://purl.uniprot.org/uniprot/T2G7L8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1121448:DGI_RS07615 ^@ http://purl.uniprot.org/uniprot/T2GC06 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit.|||Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. http://togogenome.org/gene/1121448:DGI_RS04790 ^@ http://purl.uniprot.org/uniprot/T2GAD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS04055 ^@ http://purl.uniprot.org/uniprot/T2GA06 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS06815 ^@ http://purl.uniprot.org/uniprot/T2GAG9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS06360 ^@ http://purl.uniprot.org/uniprot/T2GAP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS06160 ^@ http://purl.uniprot.org/uniprot/T2GAK8 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/1121448:DGI_RS10255 ^@ http://purl.uniprot.org/uniprot/T2GDK7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS05190 ^@ http://purl.uniprot.org/uniprot/T2G9V2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1121448:DGI_RS15110 ^@ http://purl.uniprot.org/uniprot/T2GED3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS13810 ^@ http://purl.uniprot.org/uniprot/T2GFL8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/1121448:DGI_RS00955 ^@ http://purl.uniprot.org/uniprot/T2G7H4 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1121448:DGI_RS02235 ^@ http://purl.uniprot.org/uniprot/T2G8B5 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/1121448:DGI_RS18660 ^@ http://purl.uniprot.org/uniprot/T2G907 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1121448:DGI_RS08960 ^@ http://purl.uniprot.org/uniprot/T2GC14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1121448:DGI_RS13010 ^@ http://purl.uniprot.org/uniprot/T2GE21 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1121448:DGI_RS12665 ^@ http://purl.uniprot.org/uniprot/T2GE62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS09750 ^@ http://purl.uniprot.org/uniprot/T2GCI0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1121448:DGI_RS12025 ^@ http://purl.uniprot.org/uniprot/T2GDZ5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/1121448:DGI_RS02900 ^@ http://purl.uniprot.org/uniprot/T2G7E5 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/1121448:DGI_RS12180 ^@ http://purl.uniprot.org/uniprot/T2GDJ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS01365 ^@ http://purl.uniprot.org/uniprot/T2G7Q2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1121448:DGI_RS12525 ^@ http://purl.uniprot.org/uniprot/T2GET7 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/1121448:DGI_RS00110 ^@ http://purl.uniprot.org/uniprot/T2G7U5 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS12430 ^@ http://purl.uniprot.org/uniprot/T2GDP6 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1121448:DGI_RS02905 ^@ http://purl.uniprot.org/uniprot/T2G8Q4 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1121448:DGI_RS07565 ^@ http://purl.uniprot.org/uniprot/T2GBZ5 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1121448:DGI_RS13315 ^@ http://purl.uniprot.org/uniprot/T2GEM3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/1121448:DGI_RS04925 ^@ http://purl.uniprot.org/uniprot/T2G9E3 ^@ Similarity ^@ Belongs to the pseudouridine synthase RluA family. http://togogenome.org/gene/1121448:DGI_RS01875 ^@ http://purl.uniprot.org/uniprot/T2G6U8 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1121448:DGI_RS07085 ^@ http://purl.uniprot.org/uniprot/T2GAM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1121448:DGI_RS06170 ^@ http://purl.uniprot.org/uniprot/T2GA54 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/1121448:DGI_RS14205 ^@ http://purl.uniprot.org/uniprot/T2GF80 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1121448:DGI_RS11855 ^@ http://purl.uniprot.org/uniprot/T2GDV9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1121448:DGI_RS05160 ^@ http://purl.uniprot.org/uniprot/T2G9I7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/1121448:DGI_RS06010 ^@ http://purl.uniprot.org/uniprot/T2GAI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS00515 ^@ http://purl.uniprot.org/uniprot/T2G789 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1121448:DGI_RS00140 ^@ http://purl.uniprot.org/uniprot/T2G6R1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/1121448:DGI_RS08865 ^@ http://purl.uniprot.org/uniprot/T2GBZ6 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1121448:DGI_RS06320 ^@ http://purl.uniprot.org/uniprot/T2GBA6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1121448:DGI_RS11100 ^@ http://purl.uniprot.org/uniprot/T2GDH0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1121448:DGI_RS01005 ^@ http://purl.uniprot.org/uniprot/T2G7A0 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/1121448:DGI_RS02530 ^@ http://purl.uniprot.org/uniprot/T2G829 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1121448:DGI_RS14855 ^@ http://purl.uniprot.org/uniprot/T2GG14 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1121448:DGI_RS12145 ^@ http://purl.uniprot.org/uniprot/T2GCR0 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/1121448:DGI_RS03545 ^@ http://purl.uniprot.org/uniprot/T2G948 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1121448:DGI_RS13070 ^@ http://purl.uniprot.org/uniprot/T2GDC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1121448:DGI_RS15620 ^@ http://purl.uniprot.org/uniprot/T2GGD9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1121448:DGI_RS03305 ^@ http://purl.uniprot.org/uniprot/T2G902 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1121448:DGI_RS13365 ^@ http://purl.uniprot.org/uniprot/T2GEM9 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1121448:DGI_RS14740 ^@ http://purl.uniprot.org/uniprot/T2GFI1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the transcriptional regulatory CopG/NikR family.|||Binds 1 nickel ion per subunit.|||Transcriptional regulator. http://togogenome.org/gene/1121448:DGI_RS11530 ^@ http://purl.uniprot.org/uniprot/T2GCE3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1121448:DGI_RS06430 ^@ http://purl.uniprot.org/uniprot/T2G9E7 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/1121448:DGI_RS08135 ^@ http://purl.uniprot.org/uniprot/T2GCE0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS04760 ^@ http://purl.uniprot.org/uniprot/T2G9S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/1121448:DGI_RS06325 ^@ http://purl.uniprot.org/uniprot/T2GAI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS02880 ^@ http://purl.uniprot.org/uniprot/T2G8Q0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1121448:DGI_RS08860 ^@ http://purl.uniprot.org/uniprot/T2GBM7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS09825 ^@ http://purl.uniprot.org/uniprot/T2GBD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS08265 ^@ http://purl.uniprot.org/uniprot/T2GBP9 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1121448:DGI_RS12050 ^@ http://purl.uniprot.org/uniprot/T2GE00 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/1121448:DGI_RS10285 ^@ http://purl.uniprot.org/uniprot/T2GCG9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS16215 ^@ http://purl.uniprot.org/uniprot/T2GFV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS16085 ^@ http://purl.uniprot.org/uniprot/T2GGH0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/1121448:DGI_RS08545 ^@ http://purl.uniprot.org/uniprot/T2GAN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS02155 ^@ http://purl.uniprot.org/uniprot/T2G899 ^@ Cofactor|||Domain|||Function|||Subcellular Location Annotation|||Subunit ^@ Binds 2 [4Fe-4S] clusters.|||Consists of three sections from the N- to the C-terminus: [4Fe-4S] cluster-binding domain, beta-sheet and C-terminal tail. The beta-sheet and the C-terminal tail interact with AprA to stabilize the AprA/AprB heterodimer.|||Cytoplasm|||Heterodimer composed of AprA and AprB (PubMed:19820092, PubMed:2158885). The heterodimers can dimerize to form heterotetramers (PubMed:2158885).|||Iron-sulfur cluster subunit of the adenylylsulfate reductase which catalyzes reversibly the reduction of adenosine 5'-phosphosulfate (APS) to sulfite and AMP during dissimilatory sulfate reduction. The iron-sulfur cluster 2 is thought to accept electrons from a still unknown electron donor and transfer electrons to the iron-sulfur cluster 1 of this protein and then onto the FAD of AprA. http://togogenome.org/gene/1121448:DGI_RS00600 ^@ http://purl.uniprot.org/uniprot/T2G7H1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS06230 ^@ http://purl.uniprot.org/uniprot/T2GAG6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS09930 ^@ http://purl.uniprot.org/uniprot/T2GCR9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1121448:DGI_RS15775 ^@ http://purl.uniprot.org/uniprot/T2GGF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS13825 ^@ http://purl.uniprot.org/uniprot/T2GDQ8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1121448:DGI_RS02660 ^@ http://purl.uniprot.org/uniprot/T2G976 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/1121448:DGI_RS08770 ^@ http://purl.uniprot.org/uniprot/T2GBR1 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/1121448:DGI_RS13510 ^@ http://purl.uniprot.org/uniprot/T2GEQ3 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS05745 ^@ http://purl.uniprot.org/uniprot/T2GA88 ^@ Similarity ^@ Belongs to the DNA photolyase class-2 family. http://togogenome.org/gene/1121448:DGI_RS01980 ^@ http://purl.uniprot.org/uniprot/T2G6W6 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1121448:DGI_RS03690 ^@ http://purl.uniprot.org/uniprot/T2G7W8 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1121448:DGI_RS03265 ^@ http://purl.uniprot.org/uniprot/T2G8V0 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/1121448:DGI_RS12935 ^@ http://purl.uniprot.org/uniprot/T2GE04 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS00235 ^@ http://purl.uniprot.org/uniprot/T2G7X3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1121448:DGI_RS16155 ^@ http://purl.uniprot.org/uniprot/T2GG73 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1121448:DGI_RS03600 ^@ http://purl.uniprot.org/uniprot/T2G9T1 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/1121448:DGI_RS04075 ^@ http://purl.uniprot.org/uniprot/T2G9E9 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS07290 ^@ http://purl.uniprot.org/uniprot/T2G9W0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1121448:DGI_RS12735 ^@ http://purl.uniprot.org/uniprot/T2GDV8 ^@ Similarity ^@ Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/1121448:DGI_RS15895 ^@ http://purl.uniprot.org/uniprot/T2GFR2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/1121448:DGI_RS13175 ^@ http://purl.uniprot.org/uniprot/T2GEP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS11990 ^@ http://purl.uniprot.org/uniprot/T2GDT3 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1121448:DGI_RS01800 ^@ http://purl.uniprot.org/uniprot/T2G833 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1121448:DGI_RS12630 ^@ http://purl.uniprot.org/uniprot/T2GEW0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1121448:DGI_RS01215 ^@ http://purl.uniprot.org/uniprot/T2G6J0 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1121448:DGI_RS16100 ^@ http://purl.uniprot.org/uniprot/T2GF21 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1121448:DGI_RS15120 ^@ http://purl.uniprot.org/uniprot/T2GG55 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1121448:DGI_RS12020 ^@ http://purl.uniprot.org/uniprot/T2GCN7 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/1121448:DGI_RS13990 ^@ http://purl.uniprot.org/uniprot/T2GEM5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS09660 ^@ http://purl.uniprot.org/uniprot/T2GD75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS01840 ^@ http://purl.uniprot.org/uniprot/T2G7Z9 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1121448:DGI_RS05725 ^@ http://purl.uniprot.org/uniprot/T2G913 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1121448:DGI_RS02430 ^@ http://purl.uniprot.org/uniprot/T2G748 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/1121448:DGI_RS06195 ^@ http://purl.uniprot.org/uniprot/T2GAL7 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/1121448:DGI_RS11485 ^@ http://purl.uniprot.org/uniprot/T2GCD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/1121448:DGI_RS10500 ^@ http://purl.uniprot.org/uniprot/T2GBS4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1121448:DGI_RS13765 ^@ http://purl.uniprot.org/uniprot/T2GEJ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1121448:DGI_RS08920 ^@ http://purl.uniprot.org/uniprot/T2GAV2 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS04940 ^@ http://purl.uniprot.org/uniprot/T2G9V4 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/1121448:DGI_RS10340 ^@ http://purl.uniprot.org/uniprot/T2GCV5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS11135 ^@ http://purl.uniprot.org/uniprot/T2GD01 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS01700 ^@ http://purl.uniprot.org/uniprot/T2G8Q1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS15740 ^@ http://purl.uniprot.org/uniprot/T2GG12 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS13775 ^@ http://purl.uniprot.org/uniprot/T2GDP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS18750 ^@ http://purl.uniprot.org/uniprot/T2GBV1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol monophosphatase superfamily. CysQ family.|||Cell membrane|||Converts adenosine-3',5'-bisphosphate (PAP) to AMP. http://togogenome.org/gene/1121448:DGI_RS00940 ^@ http://purl.uniprot.org/uniprot/T2G7N5 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1121448:DGI_RS11255 ^@ http://purl.uniprot.org/uniprot/T2GDK0 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/1121448:DGI_RS02305 ^@ http://purl.uniprot.org/uniprot/T2G723 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS00070 ^@ http://purl.uniprot.org/uniprot/T2G5U7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS07560 ^@ http://purl.uniprot.org/uniprot/T2GA14 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M32 family.|||Binds 1 zinc ion per subunit.|||Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. http://togogenome.org/gene/1121448:DGI_RS11575 ^@ http://purl.uniprot.org/uniprot/T2GDK3 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/1121448:DGI_RS13015 ^@ http://purl.uniprot.org/uniprot/T2GED5 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1121448:DGI_RS06070 ^@ http://purl.uniprot.org/uniprot/T2GA37 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Homodimer.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.|||The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.|||The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity. http://togogenome.org/gene/1121448:DGI_RS04020 ^@ http://purl.uniprot.org/uniprot/T2G828 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS01685 ^@ http://purl.uniprot.org/uniprot/T2G7W5 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/1121448:DGI_RS15440 ^@ http://purl.uniprot.org/uniprot/T2GEJ6 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/1121448:DGI_RS09670 ^@ http://purl.uniprot.org/uniprot/T2GCG4 ^@ Similarity ^@ Belongs to the polysaccharide lyase 8 family. http://togogenome.org/gene/1121448:DGI_RS12800 ^@ http://purl.uniprot.org/uniprot/T2GEZ8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 33 family. http://togogenome.org/gene/1121448:DGI_RS13030 ^@ http://purl.uniprot.org/uniprot/T2GF55 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1121448:DGI_RS00375 ^@ http://purl.uniprot.org/uniprot/T2G806 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS07210 ^@ http://purl.uniprot.org/uniprot/T2GB12 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/1121448:DGI_RS01255 ^@ http://purl.uniprot.org/uniprot/T2G7E0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1121448:DGI_RS05030 ^@ http://purl.uniprot.org/uniprot/T2G9S1 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1121448:DGI_RS01940 ^@ http://purl.uniprot.org/uniprot/T2G8T9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS08115 ^@ http://purl.uniprot.org/uniprot/T2GBL0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS05945 ^@ http://purl.uniprot.org/uniprot/T2GA18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS01770 ^@ http://purl.uniprot.org/uniprot/T2G6S9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HupC/HyaC/HydC family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS09640 ^@ http://purl.uniprot.org/uniprot/T2GC35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS16300 ^@ http://purl.uniprot.org/uniprot/T2GF57 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1121448:DGI_RS10620 ^@ http://purl.uniprot.org/uniprot/T2GD38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/1121448:DGI_RS08380 ^@ http://purl.uniprot.org/uniprot/T2GCP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS16065 ^@ http://purl.uniprot.org/uniprot/T2GFT5 ^@ Cofactor|||Subunit ^@ Binds 2 irons ions per subunit via 4 cysteine residues per iron.|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS04200 ^@ http://purl.uniprot.org/uniprot/T2G9H1 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/1121448:DGI_RS01185 ^@ http://purl.uniprot.org/uniprot/T2G7L6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS16730 ^@ http://purl.uniprot.org/uniprot/T2G793 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/1121448:DGI_RS07475 ^@ http://purl.uniprot.org/uniprot/T2GAV5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/1121448:DGI_RS08850 ^@ http://purl.uniprot.org/uniprot/T2GC48 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1121448:DGI_RS14890 ^@ http://purl.uniprot.org/uniprot/T2GFG0 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/1121448:DGI_RS08760 ^@ http://purl.uniprot.org/uniprot/T2GBL4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1121448:DGI_RS14175 ^@ http://purl.uniprot.org/uniprot/T2GDW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS02150 ^@ http://purl.uniprot.org/uniprot/T2G6Z9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-dependent oxidoreductase 2 family.|||Catalytic subunit of the adenylylsulfate reductase which catalyzes reversibly the reduction of adenosine 5'-phosphosulfate (APS) to sulfite and AMP during dissimilatory sulfate reduction.|||Consists of three sections from the N- to the C-terminus: FAD-binding domain, capping domain and helical domain. The FAD-binding domain and the capping domain slightly overlap and form a channel that may transport the substrate.|||Cytoplasm|||Heterodimer composed of AprA and AprB (PubMed:19820092, PubMed:2158885). The heterodimers can dimerize to form heterotetramers (PubMed:2158885). http://togogenome.org/gene/1121448:DGI_RS12765 ^@ http://purl.uniprot.org/uniprot/T2GD37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS07445 ^@ http://purl.uniprot.org/uniprot/T2GBA4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS07440 ^@ http://purl.uniprot.org/uniprot/T2G9Y9 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/1121448:DGI_RS10475 ^@ http://purl.uniprot.org/uniprot/T2GBR8 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1121448:DGI_RS02420 ^@ http://purl.uniprot.org/uniprot/T2G808 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/1121448:DGI_RS09180 ^@ http://purl.uniprot.org/uniprot/T2GC58 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1121448:DGI_RS12840 ^@ http://purl.uniprot.org/uniprot/T2GD51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CheZ family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS02185 ^@ http://purl.uniprot.org/uniprot/T2G8Y3 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1121448:DGI_RS16410 ^@ http://purl.uniprot.org/uniprot/T2GFY2 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1121448:DGI_RS07305 ^@ http://purl.uniprot.org/uniprot/T2GAS1 ^@ Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. http://togogenome.org/gene/1121448:DGI_RS03375 ^@ http://purl.uniprot.org/uniprot/T2G7R1 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/1121448:DGI_RS14820 ^@ http://purl.uniprot.org/uniprot/T2GG10 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1121448:DGI_RS16070 ^@ http://purl.uniprot.org/uniprot/T2GG22 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1121448:DGI_RS01165 ^@ http://purl.uniprot.org/uniprot/T2G6I1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1121448:DGI_RS11705 ^@ http://purl.uniprot.org/uniprot/T2GDT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS17450 ^@ http://purl.uniprot.org/uniprot/T2GEF5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS07040 ^@ http://purl.uniprot.org/uniprot/T2GAL4 ^@ Similarity ^@ Belongs to the FlgM family. http://togogenome.org/gene/1121448:DGI_RS05210 ^@ http://purl.uniprot.org/uniprot/T2G9J8 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/1121448:DGI_RS08270 ^@ http://purl.uniprot.org/uniprot/T2GAH7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1121448:DGI_RS10785 ^@ http://purl.uniprot.org/uniprot/T2GD62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS03535 ^@ http://purl.uniprot.org/uniprot/T2G8Z3 ^@ Similarity ^@ Belongs to the alpha-acetolactate decarboxylase family. http://togogenome.org/gene/1121448:DGI_RS07185 ^@ http://purl.uniprot.org/uniprot/T2GB07 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/1121448:DGI_RS06400 ^@ http://purl.uniprot.org/uniprot/T2G9E2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1121448:DGI_RS02450 ^@ http://purl.uniprot.org/uniprot/T2G813 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1121448:DGI_RS01625 ^@ http://purl.uniprot.org/uniprot/T2G8P1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS13280 ^@ http://purl.uniprot.org/uniprot/T2GFC9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS11125 ^@ http://purl.uniprot.org/uniprot/T2GDH6 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/1121448:DGI_RS04920 ^@ http://purl.uniprot.org/uniprot/T2GAF5 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1121448:DGI_RS05480 ^@ http://purl.uniprot.org/uniprot/T2GAT1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1121448:DGI_RS16340 ^@ http://purl.uniprot.org/uniprot/T2GG65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS09150 ^@ http://purl.uniprot.org/uniprot/T2GBS6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/1121448:DGI_RS13005 ^@ http://purl.uniprot.org/uniprot/T2GF42 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1121448:DGI_RS01865 ^@ http://purl.uniprot.org/uniprot/T2G7P3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/1121448:DGI_RS06620 ^@ http://purl.uniprot.org/uniprot/T2GAD1 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1121448:DGI_RS10065 ^@ http://purl.uniprot.org/uniprot/T2GDF9 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/1121448:DGI_RS08260 ^@ http://purl.uniprot.org/uniprot/T2GBC5 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1121448:DGI_RS07195 ^@ http://purl.uniprot.org/uniprot/T2GB58 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1121448:DGI_RS02140 ^@ http://purl.uniprot.org/uniprot/T2G7V3 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/1121448:DGI_RS13640 ^@ http://purl.uniprot.org/uniprot/T2GFJ4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1121448:DGI_RS14020 ^@ http://purl.uniprot.org/uniprot/T2GF01 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1121448:DGI_RS02045 ^@ http://purl.uniprot.org/uniprot/T2G6Y2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/1121448:DGI_RS12865 ^@ http://purl.uniprot.org/uniprot/T2GEA2 ^@ Caution|||Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).|||In the C-terminal section; belongs to the IspF family.|||In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS12070 ^@ http://purl.uniprot.org/uniprot/T2GCP6 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnA subfamily.|||Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/1121448:DGI_RS07095 ^@ http://purl.uniprot.org/uniprot/T2G9S4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/1121448:DGI_RS03960 ^@ http://purl.uniprot.org/uniprot/T2G8V5 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1121448:DGI_RS14635 ^@ http://purl.uniprot.org/uniprot/T2GFG1 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/1121448:DGI_RS06510 ^@ http://purl.uniprot.org/uniprot/T2G9G0 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1121448:DGI_RS00655 ^@ http://purl.uniprot.org/uniprot/T2G747 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS08275 ^@ http://purl.uniprot.org/uniprot/T2GBU2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1121448:DGI_RS03955 ^@ http://purl.uniprot.org/uniprot/T2G9Y8 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/1121448:DGI_RS09690 ^@ http://purl.uniprot.org/uniprot/T2GC43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS13335 ^@ http://purl.uniprot.org/uniprot/T2GEC1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1121448:DGI_RS13815 ^@ http://purl.uniprot.org/uniprot/T2GEK0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS04445 ^@ http://purl.uniprot.org/uniprot/T2G8A5 ^@ Function|||Similarity ^@ Belongs to the vsr family.|||May nick specific sequences that contain T:G mispairs resulting from m5C-deamination. http://togogenome.org/gene/1121448:DGI_RS15645 ^@ http://purl.uniprot.org/uniprot/T2GFZ7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/1121448:DGI_RS08620 ^@ http://purl.uniprot.org/uniprot/T2GC03 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS07610 ^@ http://purl.uniprot.org/uniprot/Q9F0J6|||http://purl.uniprot.org/uniprot/T2GBE0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Binds 1 FMN per monomer.|||Binds 2 iron ions per monomer.|||Catalyzes the four-electron reduction of one oxygen molecule to two water molecules.|||Homodimer.|||In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/1121448:DGI_RS09155 ^@ http://purl.uniprot.org/uniprot/T2GC53 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1121448:DGI_RS11130 ^@ http://purl.uniprot.org/uniprot/T2GE46 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/1121448:DGI_RS07130 ^@ http://purl.uniprot.org/uniprot/T2GBQ4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS15915 ^@ http://purl.uniprot.org/uniprot/T2GGG3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1121448:DGI_RS06050 ^@ http://purl.uniprot.org/uniprot/T2GAD3 ^@ Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family. http://togogenome.org/gene/1121448:DGI_RS04730 ^@ http://purl.uniprot.org/uniprot/T2G8F3 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1121448:DGI_RS08020 ^@ http://purl.uniprot.org/uniprot/T2GC97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/1121448:DGI_RS01180 ^@ http://purl.uniprot.org/uniprot/T2G7C9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS12775 ^@ http://purl.uniprot.org/uniprot/T2GEZ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS13415 ^@ http://purl.uniprot.org/uniprot/T2GEN7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Belongs to the pseudouridine synthase RluA family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS15235 ^@ http://purl.uniprot.org/uniprot/T2GEF7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1121448:DGI_RS02125 ^@ http://purl.uniprot.org/uniprot/T2G6Z6 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/1121448:DGI_RS12095 ^@ http://purl.uniprot.org/uniprot/T2GCQ1 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1121448:DGI_RS12705 ^@ http://purl.uniprot.org/uniprot/T2GEX8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/1121448:DGI_RS09685 ^@ http://purl.uniprot.org/uniprot/T2GD78 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS13075 ^@ http://purl.uniprot.org/uniprot/T2GEN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1121448:DGI_RS09830 ^@ http://purl.uniprot.org/uniprot/T2GCQ0 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/1121448:DGI_RS05140 ^@ http://purl.uniprot.org/uniprot/T2G9U2 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1121448:DGI_RS09910 ^@ http://purl.uniprot.org/uniprot/T2GDC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS02485 ^@ http://purl.uniprot.org/uniprot/T2G758 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS11870 ^@ http://purl.uniprot.org/uniprot/T2GDR0 ^@ Function|||Similarity ^@ Belongs to the Thz kinase family.|||Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). http://togogenome.org/gene/1121448:DGI_RS07405 ^@ http://purl.uniprot.org/uniprot/T2GAU1 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1121448:DGI_RS07340 ^@ http://purl.uniprot.org/uniprot/T2GB40 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1121448:DGI_RS13165 ^@ http://purl.uniprot.org/uniprot/T2GEK3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS18650 ^@ http://purl.uniprot.org/uniprot/T2G971 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1121448:DGI_RS05180 ^@ http://purl.uniprot.org/uniprot/T2GAL3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1121448:DGI_RS10170 ^@ http://purl.uniprot.org/uniprot/T2GBK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the hemerythrin family.|||Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS04290 ^@ http://purl.uniprot.org/uniprot/T2G9D6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS07080 ^@ http://purl.uniprot.org/uniprot/T2GBP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS13085 ^@ http://purl.uniprot.org/uniprot/T2GE77 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1121448:DGI_RS10205 ^@ http://purl.uniprot.org/uniprot/T2GDJ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS14490 ^@ http://purl.uniprot.org/uniprot/T2GFD1 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/1121448:DGI_RS02100 ^@ http://purl.uniprot.org/uniprot/T2G890 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS04110 ^@ http://purl.uniprot.org/uniprot/T2G8Y1 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/1121448:DGI_RS12330 ^@ http://purl.uniprot.org/uniprot/T2GDM4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1121448:DGI_RS03070 ^@ http://purl.uniprot.org/uniprot/T2G8U8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RlpA family.|||Cell membrane|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/1121448:DGI_RS15070 ^@ http://purl.uniprot.org/uniprot/T2GG46 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/1121448:DGI_RS12855 ^@ http://purl.uniprot.org/uniprot/T2GF08 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1121448:DGI_RS15730 ^@ http://purl.uniprot.org/uniprot/T2GFX1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1121448:DGI_RS01965 ^@ http://purl.uniprot.org/uniprot/T2G8U4 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1121448:DGI_RS01385 ^@ http://purl.uniprot.org/uniprot/T2G7G0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS06820 ^@ http://purl.uniprot.org/uniprot/T2GAT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/1121448:DGI_RS01235 ^@ http://purl.uniprot.org/uniprot/T2G7M7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS01545 ^@ http://purl.uniprot.org/uniprot/T2G7I8 ^@ Cofactor ^@ Binds 4 heme c groups covalently per monomer. http://togogenome.org/gene/1121448:DGI_RS15195 ^@ http://purl.uniprot.org/uniprot/T2GG68 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/1121448:DGI_RS07030 ^@ http://purl.uniprot.org/uniprot/T2GB24 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1121448:DGI_RS13795 ^@ http://purl.uniprot.org/uniprot/T2GEV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1121448:DGI_RS04040 ^@ http://purl.uniprot.org/uniprot/T2G990 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS08305 ^@ http://purl.uniprot.org/uniprot/T2GCH1 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/1121448:DGI_RS08360 ^@ http://purl.uniprot.org/uniprot/T2GBE5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS13195 ^@ http://purl.uniprot.org/uniprot/T2GDE5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS03220 ^@ http://purl.uniprot.org/uniprot/T2G7N3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1121448:DGI_RS08295 ^@ http://purl.uniprot.org/uniprot/T2GAI2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1121448:DGI_RS11385 ^@ http://purl.uniprot.org/uniprot/T2GCB7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS10115 ^@ http://purl.uniprot.org/uniprot/T2GDH1 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1121448:DGI_RS04900 ^@ http://purl.uniprot.org/uniprot/T2G9D9 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS07395 ^@ http://purl.uniprot.org/uniprot/T2GB96 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1121448:DGI_RS01250 ^@ http://purl.uniprot.org/uniprot/T2G8H9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1121448:DGI_RS11535 ^@ http://purl.uniprot.org/uniprot/T2GDQ0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1121448:DGI_RS09070 ^@ http://purl.uniprot.org/uniprot/T2GBR2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS12980 ^@ http://purl.uniprot.org/uniprot/T2GF37 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1121448:DGI_RS08875 ^@ http://purl.uniprot.org/uniprot/T2GC54 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1121448:DGI_RS06380 ^@ http://purl.uniprot.org/uniprot/T2GAQ4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/1121448:DGI_RS04885 ^@ http://purl.uniprot.org/uniprot/T2G8I2 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/1121448:DGI_RS09835 ^@ http://purl.uniprot.org/uniprot/T2GDB0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS10130 ^@ http://purl.uniprot.org/uniprot/T2GCW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS09215 ^@ http://purl.uniprot.org/uniprot/T2GCB8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS03385 ^@ http://purl.uniprot.org/uniprot/T2G9P3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1121448:DGI_RS13805 ^@ http://purl.uniprot.org/uniprot/T2GF15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS09435 ^@ http://purl.uniprot.org/uniprot/T2GCF7 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1121448:DGI_RS16090 ^@ http://purl.uniprot.org/uniprot/T2GFT8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/1121448:DGI_RS12570 ^@ http://purl.uniprot.org/uniprot/T2GCZ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1121448:DGI_RS04720 ^@ http://purl.uniprot.org/uniprot/T2G9A0 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1121448:DGI_RS09790 ^@ http://purl.uniprot.org/uniprot/T2GD98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS13300 ^@ http://purl.uniprot.org/uniprot/T2GER5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/1121448:DGI_RS12975 ^@ http://purl.uniprot.org/uniprot/T2GEH6 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1121448:DGI_RS07705 ^@ http://purl.uniprot.org/uniprot/T2GBG3 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/1121448:DGI_RS12315 ^@ http://purl.uniprot.org/uniprot/T2GCU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS09625 ^@ http://purl.uniprot.org/uniprot/T2GB98 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1121448:DGI_RS15905 ^@ http://purl.uniprot.org/uniprot/T2GEY0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/1121448:DGI_RS06465 ^@ http://purl.uniprot.org/uniprot/T2GAR8 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.|||Membrane http://togogenome.org/gene/1121448:DGI_RS08650 ^@ http://purl.uniprot.org/uniprot/T2GCM9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS16205 ^@ http://purl.uniprot.org/uniprot/T2GG81 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/1121448:DGI_RS14190 ^@ http://purl.uniprot.org/uniprot/T2GEQ8 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/1121448:DGI_RS03065 ^@ http://purl.uniprot.org/uniprot/T2G7H8 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1121448:DGI_RS15845 ^@ http://purl.uniprot.org/uniprot/T2GFQ5 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/1121448:DGI_RS02425 ^@ http://purl.uniprot.org/uniprot/T2G8B3 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/1121448:DGI_RS12485 ^@ http://purl.uniprot.org/uniprot/T2GE32 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the malate synthase family. GlcB subfamily.|||Cytoplasm|||Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1121448:DGI_RS12885 ^@ http://purl.uniprot.org/uniprot/T2GDZ3 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/1121448:DGI_RS11805 ^@ http://purl.uniprot.org/uniprot/T2GDU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS10550 ^@ http://purl.uniprot.org/uniprot/T2GBU6 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/1121448:DGI_RS06255 ^@ http://purl.uniprot.org/uniprot/T2GAH1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS02010 ^@ http://purl.uniprot.org/uniprot/T2G868 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1121448:DGI_RS03100 ^@ http://purl.uniprot.org/uniprot/T2G9I9 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/1121448:DGI_RS05680 ^@ http://purl.uniprot.org/uniprot/T2GAC7 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1121448:DGI_RS09035 ^@ http://purl.uniprot.org/uniprot/T2GAX4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS07860 ^@ http://purl.uniprot.org/uniprot/T2GA74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrC/TusE family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS15755 ^@ http://purl.uniprot.org/uniprot/T2GFX3 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1121448:DGI_RS05880 ^@ http://purl.uniprot.org/uniprot/T2G942 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/1121448:DGI_RS12720 ^@ http://purl.uniprot.org/uniprot/T2GD26 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS01080 ^@ http://purl.uniprot.org/uniprot/T2G7B1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS15980 ^@ http://purl.uniprot.org/uniprot/T2GEZ7 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1121448:DGI_RS03245 ^@ http://purl.uniprot.org/uniprot/T2G7N7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS01160 ^@ http://purl.uniprot.org/uniprot/T2G7L0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1121448:DGI_RS04305 ^@ http://purl.uniprot.org/uniprot/T2GA52 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1121448:DGI_RS07400 ^@ http://purl.uniprot.org/uniprot/T2GBV9 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1121448:DGI_RS07145 ^@ http://purl.uniprot.org/uniprot/T2G9T4 ^@ Similarity ^@ Belongs to the cytochrome c-552 family. http://togogenome.org/gene/1121448:DGI_RS05270 ^@ http://purl.uniprot.org/uniprot/T2G8Q7 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/1121448:DGI_RS07680 ^@ http://purl.uniprot.org/uniprot/T2GC23 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS07715 ^@ http://purl.uniprot.org/uniprot/T2GB01 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1121448:DGI_RS13420 ^@ http://purl.uniprot.org/uniprot/T2GDI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS05455 ^@ http://purl.uniprot.org/uniprot/T2GAS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS13495 ^@ http://purl.uniprot.org/uniprot/T2GEV3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS18460 ^@ http://purl.uniprot.org/uniprot/T2GDM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1121448:DGI_RS19165 ^@ http://purl.uniprot.org/uniprot/T2G910 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1121448:DGI_RS04715 ^@ http://purl.uniprot.org/uniprot/T2GAB7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS05040 ^@ http://purl.uniprot.org/uniprot/T2G9X5 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/1121448:DGI_RS16170 ^@ http://purl.uniprot.org/uniprot/T2GG37 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1121448:DGI_RS14470 ^@ http://purl.uniprot.org/uniprot/T2GFV9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1121448:DGI_RS12055 ^@ http://purl.uniprot.org/uniprot/T2GEK1 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/1121448:DGI_RS13820 ^@ http://purl.uniprot.org/uniprot/T2GEW3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpB RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpA.|||Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H). http://togogenome.org/gene/1121448:DGI_RS02390 ^@ http://purl.uniprot.org/uniprot/T2G921 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/1121448:DGI_RS08080 ^@ http://purl.uniprot.org/uniprot/T2GCB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS01135 ^@ http://purl.uniprot.org/uniprot/T2G7K5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1121448:DGI_RS11420 ^@ http://purl.uniprot.org/uniprot/T2GE90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1121448:DGI_RS06020 ^@ http://purl.uniprot.org/uniprot/T2GA29 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS00185 ^@ http://purl.uniprot.org/uniprot/T2G7W2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1121448:DGI_RS15170 ^@ http://purl.uniprot.org/uniprot/T2GFA1 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/1121448:DGI_RS02225 ^@ http://purl.uniprot.org/uniprot/T2G872 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/1121448:DGI_RS10650 ^@ http://purl.uniprot.org/uniprot/T2GBY2 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1121448:DGI_RS14760 ^@ http://purl.uniprot.org/uniprot/T2GE68 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/1121448:DGI_RS01140 ^@ http://purl.uniprot.org/uniprot/T2G6H7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1121448:DGI_RS18680 ^@ http://purl.uniprot.org/uniprot/T2G9H6 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1121448:DGI_RS05560 ^@ http://purl.uniprot.org/uniprot/T2GA85 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS06275 ^@ http://purl.uniprot.org/uniprot/T2GA72 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/1121448:DGI_RS12925 ^@ http://purl.uniprot.org/uniprot/T2GEG8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1121448:DGI_RS02770 ^@ http://purl.uniprot.org/uniprot/T2G8H8 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS12750 ^@ http://purl.uniprot.org/uniprot/T2GEY8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS12435 ^@ http://purl.uniprot.org/uniprot/T2GE24 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1121448:DGI_RS02690 ^@ http://purl.uniprot.org/uniprot/T2G857 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1121448:DGI_RS02975 ^@ http://purl.uniprot.org/uniprot/T2G8B7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1121448:DGI_RS10155 ^@ http://purl.uniprot.org/uniprot/T2GDI3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS08085 ^@ http://purl.uniprot.org/uniprot/T2GB76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS14870 ^@ http://purl.uniprot.org/uniprot/T2GE88 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1121448:DGI_RS08350 ^@ http://purl.uniprot.org/uniprot/T2GBV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS00490 ^@ http://purl.uniprot.org/uniprot/T2G775 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1121448:DGI_RS11860 ^@ http://purl.uniprot.org/uniprot/T2GEH0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1121448:DGI_RS01275 ^@ http://purl.uniprot.org/uniprot/T2G8I3 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1121448:DGI_RS10430 ^@ http://purl.uniprot.org/uniprot/T2GD22 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1121448:DGI_RS16375 ^@ http://purl.uniprot.org/uniprot/T2GGA1 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/1121448:DGI_RS12225 ^@ http://purl.uniprot.org/uniprot/T2GEM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS05230 ^@ http://purl.uniprot.org/uniprot/T2GAM4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS11670 ^@ http://purl.uniprot.org/uniprot/T2GD87 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/1121448:DGI_RS08675 ^@ http://purl.uniprot.org/uniprot/T2GC13 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/1121448:DGI_RS05010 ^@ http://purl.uniprot.org/uniprot/T2G8K7 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/1121448:DGI_RS03135 ^@ http://purl.uniprot.org/uniprot/T2G8G4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1121448:DGI_RS05625 ^@ http://purl.uniprot.org/uniprot/T2G8X2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS16330 ^@ http://purl.uniprot.org/uniprot/T2GGI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family. GSP D subfamily.|||Cell outer membrane http://togogenome.org/gene/1121448:DGI_RS14390 ^@ http://purl.uniprot.org/uniprot/T2GFB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1121448:DGI_RS13115 ^@ http://purl.uniprot.org/uniprot/T2GEJ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS08810 ^@ http://purl.uniprot.org/uniprot/T2GBM1 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/1121448:DGI_RS02460 ^@ http://purl.uniprot.org/uniprot/T2G753 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/1121448:DGI_RS12310 ^@ http://purl.uniprot.org/uniprot/T2GDZ7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1121448:DGI_RS13630 ^@ http://purl.uniprot.org/uniprot/T2GDM1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS07070 ^@ http://purl.uniprot.org/uniprot/T2GAY2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS16370 ^@ http://purl.uniprot.org/uniprot/T2GF71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS09025 ^@ http://purl.uniprot.org/uniprot/T2GBQ6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/1121448:DGI_RS00900 ^@ http://purl.uniprot.org/uniprot/T2G785 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/1121448:DGI_RS10860 ^@ http://purl.uniprot.org/uniprot/T2GC20 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/1121448:DGI_RS05785 ^@ http://purl.uniprot.org/uniprot/T2GB15 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1121448:DGI_RS12660 ^@ http://purl.uniprot.org/uniprot/T2GDU2 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1121448:DGI_RS08245 ^@ http://purl.uniprot.org/uniprot/T2GBT7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1121448:DGI_RS03160 ^@ http://purl.uniprot.org/uniprot/T2G8G8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/1121448:DGI_RS13025 ^@ http://purl.uniprot.org/uniprot/T2GEJ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1121448:DGI_RS00605 ^@ http://purl.uniprot.org/uniprot/T2G871 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS13745 ^@ http://purl.uniprot.org/uniprot/T2GEU8 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1121448:DGI_RS12680 ^@ http://purl.uniprot.org/uniprot/T2GEX0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS05980 ^@ http://purl.uniprot.org/uniprot/T2G961 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1121448:DGI_RS10375 ^@ http://purl.uniprot.org/uniprot/T2GD14 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/1121448:DGI_RS09645 ^@ http://purl.uniprot.org/uniprot/T2GCF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS01470 ^@ http://purl.uniprot.org/uniprot/T2G8L4 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1121448:DGI_RS10110 ^@ http://purl.uniprot.org/uniprot/T2GCV6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS08965 ^@ http://purl.uniprot.org/uniprot/T2GAW1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1121448:DGI_RS06985 ^@ http://purl.uniprot.org/uniprot/T2GBM8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1121448:DGI_RS09110 ^@ http://purl.uniprot.org/uniprot/T2GCA1 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/1121448:DGI_RS15855 ^@ http://purl.uniprot.org/uniprot/T2GEX2 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1121448:DGI_RS12175 ^@ http://purl.uniprot.org/uniprot/T2GEL9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS00895 ^@ http://purl.uniprot.org/uniprot/T2G8C3 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1121448:DGI_RS03560 ^@ http://purl.uniprot.org/uniprot/T2G8Z7 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1121448:DGI_RS13105 ^@ http://purl.uniprot.org/uniprot/T2GF99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1121448:DGI_RS17020 ^@ http://purl.uniprot.org/uniprot/T2GB32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS11785 ^@ http://purl.uniprot.org/uniprot/T2GEF9 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1121448:DGI_RS01100 ^@ http://purl.uniprot.org/uniprot/T2G8F5 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1121448:DGI_RS02860 ^@ http://purl.uniprot.org/uniprot/T2G9C0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS16725 ^@ http://purl.uniprot.org/uniprot/T2G7F1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS15715 ^@ http://purl.uniprot.org/uniprot/T2GG08 ^@ Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/1121448:DGI_RS07910 ^@ http://purl.uniprot.org/uniprot/T2GA86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS03780 ^@ http://purl.uniprot.org/uniprot/T2G9V8 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1121448:DGI_RS06700 ^@ http://purl.uniprot.org/uniprot/T2G9J5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the CobB/CobQ family.|||Involved in acetate metabolism.|||The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site. http://togogenome.org/gene/1121448:DGI_RS08820 ^@ http://purl.uniprot.org/uniprot/T2GAT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS08365 ^@ http://purl.uniprot.org/uniprot/T2GBR1 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/1121448:DGI_RS05940 ^@ http://purl.uniprot.org/uniprot/T2GB42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS15785 ^@ http://purl.uniprot.org/uniprot/T2GFX6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS13605 ^@ http://purl.uniprot.org/uniprot/T2GDL6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS15390 ^@ http://purl.uniprot.org/uniprot/T2GEI6 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/1121448:DGI_RS13185 ^@ http://purl.uniprot.org/uniprot/T2GE94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS01970 ^@ http://purl.uniprot.org/uniprot/T2G7R5 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1121448:DGI_RS12445 ^@ http://purl.uniprot.org/uniprot/T2GE74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS12460 ^@ http://purl.uniprot.org/uniprot/T2GE28 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1121448:DGI_RS05465 ^@ http://purl.uniprot.org/uniprot/T2GA10 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1121448:DGI_RS05505 ^@ http://purl.uniprot.org/uniprot/T2GAT6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS05670 ^@ http://purl.uniprot.org/uniprot/T2GA75 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1121448:DGI_RS03620 ^@ http://purl.uniprot.org/uniprot/T2G963 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1121448:DGI_RS05200 ^@ http://purl.uniprot.org/uniprot/T2GA07 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1121448:DGI_RS08285 ^@ http://purl.uniprot.org/uniprot/T2GBD0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1121448:DGI_RS10625 ^@ http://purl.uniprot.org/uniprot/T2GBX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STT3 family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS14920 ^@ http://purl.uniprot.org/uniprot/T2GE98 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/1121448:DGI_RS08095 ^@ http://purl.uniprot.org/uniprot/T2GAC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS13140 ^@ http://purl.uniprot.org/uniprot/T2GEJ9 ^@ Caution|||Function|||Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS03235 ^@ http://purl.uniprot.org/uniprot/T2G8I4 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/1121448:DGI_RS00470 ^@ http://purl.uniprot.org/uniprot/T2G631 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1121448:DGI_RS10165 ^@ http://purl.uniprot.org/uniprot/T2GCR6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1121448:DGI_RS00635 ^@ http://purl.uniprot.org/uniprot/T2G742 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/1121448:DGI_RS00210 ^@ http://purl.uniprot.org/uniprot/Q9KIT1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the flavoredoxin family.|||Binds 1 FMN per subunit.|||Homodimer.|||Participates in the reduction of hydrogensulfite from hydrogen. http://togogenome.org/gene/1121448:DGI_RS07810 ^@ http://purl.uniprot.org/uniprot/T2GB22 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/1121448:DGI_RS06675 ^@ http://purl.uniprot.org/uniprot/T2G9J1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS15325 ^@ http://purl.uniprot.org/uniprot/T2GFN2 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/1121448:DGI_RS15910 ^@ http://purl.uniprot.org/uniprot/T2GG36 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer. http://togogenome.org/gene/1121448:DGI_RS12990 ^@ http://purl.uniprot.org/uniprot/T2GEC9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1121448:DGI_RS16020 ^@ http://purl.uniprot.org/uniprot/T2GFS9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1121448:DGI_RS13050 ^@ http://purl.uniprot.org/uniprot/T2GEM4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1121448:DGI_RS08300 ^@ http://purl.uniprot.org/uniprot/T2GBU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS15955 ^@ http://purl.uniprot.org/uniprot/T2GEZ2 ^@ Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. http://togogenome.org/gene/1121448:DGI_RS17275 ^@ http://purl.uniprot.org/uniprot/T2GBZ2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS15970 ^@ http://purl.uniprot.org/uniprot/T2GFS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS13000 ^@ http://purl.uniprot.org/uniprot/T2GEI2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1121448:DGI_RS02200 ^@ http://purl.uniprot.org/uniprot/T2G708 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS14140 ^@ http://purl.uniprot.org/uniprot/T2GEQ1 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1121448:DGI_RS10040 ^@ http://purl.uniprot.org/uniprot/T2GDF3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/1121448:DGI_RS18465 ^@ http://purl.uniprot.org/uniprot/T2GEC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1121448:DGI_RS06120 ^@ http://purl.uniprot.org/uniprot/T2GA47 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/1121448:DGI_RS01295 ^@ http://purl.uniprot.org/uniprot/T2G7U8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS15935 ^@ http://purl.uniprot.org/uniprot/T2GG40 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1121448:DGI_RS11815 ^@ http://purl.uniprot.org/uniprot/T2GDB2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1121448:DGI_RS14370 ^@ http://purl.uniprot.org/uniprot/T2GEU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS00380 ^@ http://purl.uniprot.org/uniprot/T2G6W4 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1121448:DGI_RS09370 ^@ http://purl.uniprot.org/uniprot/T2GC96 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/1121448:DGI_RS08330 ^@ http://purl.uniprot.org/uniprot/T2GCH6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS16010 ^@ http://purl.uniprot.org/uniprot/T2GG52 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/1121448:DGI_RS03280 ^@ http://purl.uniprot.org/uniprot/T2G9M7 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/1121448:DGI_RS06405 ^@ http://purl.uniprot.org/uniprot/T2GAQ7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1121448:DGI_RS15125 ^@ http://purl.uniprot.org/uniprot/T2GF89 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS00255 ^@ http://purl.uniprot.org/uniprot/T2G781 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS13065 ^@ http://purl.uniprot.org/uniprot/T2GEI8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1121448:DGI_RS12390 ^@ http://purl.uniprot.org/uniprot/T2GCW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS03095 ^@ http://purl.uniprot.org/uniprot/T2G8W5 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1121448:DGI_RS01150 ^@ http://purl.uniprot.org/uniprot/T2G8G3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/1121448:DGI_RS07815 ^@ http://purl.uniprot.org/uniprot/T2GBE2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1121448:DGI_RS01765 ^@ http://purl.uniprot.org/uniprot/T2G7Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS09220 ^@ http://purl.uniprot.org/uniprot/T2GCY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS10460 ^@ http://purl.uniprot.org/uniprot/T2GDQ3 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1121448:DGI_RS12755 ^@ http://purl.uniprot.org/uniprot/T2GDW3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1121448:DGI_RS12140 ^@ http://purl.uniprot.org/uniprot/T2GDW2 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/1121448:DGI_RS08165 ^@ http://purl.uniprot.org/uniprot/T2GBN5 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1121448:DGI_RS00890 ^@ http://purl.uniprot.org/uniprot/T2G7M5 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS13595 ^@ http://purl.uniprot.org/uniprot/T2GEG5 ^@ Function ^@ Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/1121448:DGI_RS13970 ^@ http://purl.uniprot.org/uniprot/T2GEZ1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS04150 ^@ http://purl.uniprot.org/uniprot/T2G9G3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/1121448:DGI_RS08830 ^@ http://purl.uniprot.org/uniprot/T2GCQ8 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1121448:DGI_RS10350 ^@ http://purl.uniprot.org/uniprot/T2GD09 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1121448:DGI_RS09020 ^@ http://purl.uniprot.org/uniprot/T2GCU3 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/1121448:DGI_RS14275 ^@ http://purl.uniprot.org/uniprot/T2GDY4 ^@ Similarity ^@ Belongs to the desulfoferrodoxin family. http://togogenome.org/gene/1121448:DGI_RS05825 ^@ http://purl.uniprot.org/uniprot/T2GAA0 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/1121448:DGI_RS14650 ^@ http://purl.uniprot.org/uniprot/T2GFB4 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/1121448:DGI_RS14900 ^@ http://purl.uniprot.org/uniprot/T2GFK6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1121448:DGI_RS05720 ^@ http://purl.uniprot.org/uniprot/T2GA83 ^@ Function|||Subunit ^@ Interacts with sigma-54.|||Required for activation of most nif operons, which are directly involved in nitrogen fixation. http://togogenome.org/gene/1121448:DGI_RS13330 ^@ http://purl.uniprot.org/uniprot/T2GFD7 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/1121448:DGI_RS13120 ^@ http://purl.uniprot.org/uniprot/T2GDD2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1121448:DGI_RS01090 ^@ http://purl.uniprot.org/uniprot/T2G6H0 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1121448:DGI_RS12335 ^@ http://purl.uniprot.org/uniprot/T2GE02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS07115 ^@ http://purl.uniprot.org/uniprot/T2GAZ2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS08755 ^@ http://purl.uniprot.org/uniprot/T2GCP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS12640 ^@ http://purl.uniprot.org/uniprot/T2GE58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS07900 ^@ http://purl.uniprot.org/uniprot/T2GB39 ^@ Cofactor ^@ Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1121448:DGI_RS15735 ^@ http://purl.uniprot.org/uniprot/T2GEV0 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS00220 ^@ http://purl.uniprot.org/uniprot/T2G717 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1121448:DGI_RS04035 ^@ http://purl.uniprot.org/uniprot/T2G8W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Membrane http://togogenome.org/gene/1121448:DGI_RS05660 ^@ http://purl.uniprot.org/uniprot/T2GAY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS16230 ^@ http://purl.uniprot.org/uniprot/T2GG85 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1121448:DGI_RS04100 ^@ http://purl.uniprot.org/uniprot/T2G9F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS03145 ^@ http://purl.uniprot.org/uniprot/T2G7L7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1121448:DGI_RS04175 ^@ http://purl.uniprot.org/uniprot/T2G9G7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS06185 ^@ http://purl.uniprot.org/uniprot/T2GAF7 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Arsenite methyltransferase family. http://togogenome.org/gene/1121448:DGI_RS07370 ^@ http://purl.uniprot.org/uniprot/T2GB92 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1121448:DGI_RS14790 ^@ http://purl.uniprot.org/uniprot/T2GFJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS01500 ^@ http://purl.uniprot.org/uniprot/T2G7I1 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS12030 ^@ http://purl.uniprot.org/uniprot/T2GEJ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/1121448:DGI_RS16130 ^@ http://purl.uniprot.org/uniprot/T2GG70 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS11120 ^@ http://purl.uniprot.org/uniprot/T2GC70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/1121448:DGI_RS06715 ^@ http://purl.uniprot.org/uniprot/T2GAE8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/1121448:DGI_RS11550 ^@ http://purl.uniprot.org/uniprot/T2GDJ8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1121448:DGI_RS00670 ^@ http://purl.uniprot.org/uniprot/T2G7I6 ^@ Cofactor ^@ Binds 4 heme c groups covalently per monomer. http://togogenome.org/gene/1121448:DGI_RS00840 ^@ http://purl.uniprot.org/uniprot/T2G7L5 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1121448:DGI_RS15260 ^@ http://purl.uniprot.org/uniprot/T2GEG1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS04455 ^@ http://purl.uniprot.org/uniprot/T2GA77 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/1121448:DGI_RS16075 ^@ http://purl.uniprot.org/uniprot/T2GF16 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/1121448:DGI_RS19475 ^@ http://purl.uniprot.org/uniprot/T2GDU5 ^@ Function ^@ Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/1121448:DGI_RS11730 ^@ http://purl.uniprot.org/uniprot/T2GDT6 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1121448:DGI_RS15330 ^@ http://purl.uniprot.org/uniprot/T2GG89 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/1121448:DGI_RS10175 ^@ http://purl.uniprot.org/uniprot/T2GCX3 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1121448:DGI_RS12700 ^@ http://purl.uniprot.org/uniprot/T2GEC7 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/1121448:DGI_RS06285 ^@ http://purl.uniprot.org/uniprot/T2G9B9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1121448:DGI_RS10655 ^@ http://purl.uniprot.org/uniprot/T2GD91 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1121448:DGI_RS04310 ^@ http://purl.uniprot.org/uniprot/T2G919 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/1121448:DGI_RS14030 ^@ http://purl.uniprot.org/uniprot/T2GF54 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/1121448:DGI_RS06060 ^@ http://purl.uniprot.org/uniprot/T2GAI9 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1121448:DGI_RS07515 ^@ http://purl.uniprot.org/uniprot/T2GBC0 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1121448:DGI_RS11605 ^@ http://purl.uniprot.org/uniprot/T2GCF6 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS02095 ^@ http://purl.uniprot.org/uniprot/T2G6Z2 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1121448:DGI_RS00320 ^@ http://purl.uniprot.org/uniprot/T2G5Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS13125 ^@ http://purl.uniprot.org/uniprot/T2GEN8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1121448:DGI_RS10425 ^@ http://purl.uniprot.org/uniprot/T2GBQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS06390 ^@ http://purl.uniprot.org/uniprot/T2GA94 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1121448:DGI_RS08395 ^@ http://purl.uniprot.org/uniprot/T2GBX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1121448:DGI_RS07890 ^@ http://purl.uniprot.org/uniprot/T2GBK2 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1121448:DGI_RS14050 ^@ http://purl.uniprot.org/uniprot/T2GDU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS04675 ^@ http://purl.uniprot.org/uniprot/T2G9K1 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1121448:DGI_RS15240 ^@ http://purl.uniprot.org/uniprot/T2GFR0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1121448:DGI_RS10515 ^@ http://purl.uniprot.org/uniprot/T2GCL8 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1121448:DGI_RS06525 ^@ http://purl.uniprot.org/uniprot/T2GAM3 ^@ Similarity ^@ Belongs to the bacterial glucokinase family. http://togogenome.org/gene/1121448:DGI_RS04250 ^@ http://purl.uniprot.org/uniprot/T2G9I0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1121448:DGI_RS06035 ^@ http://purl.uniprot.org/uniprot/T2GAI5 ^@ Function|||Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family.|||This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). http://togogenome.org/gene/1121448:DGI_RS13345 ^@ http://purl.uniprot.org/uniprot/T2GDH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS00510 ^@ http://purl.uniprot.org/uniprot/T2G706 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/1121448:DGI_RS10050 ^@ http://purl.uniprot.org/uniprot/T2GCP0 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1121448:DGI_RS08550 ^@ http://purl.uniprot.org/uniprot/T2GBY8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon. http://togogenome.org/gene/1121448:DGI_RS06605 ^@ http://purl.uniprot.org/uniprot/T2G9H8 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/1121448:DGI_RS01535 ^@ http://purl.uniprot.org/uniprot/T2G7Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS14180 ^@ http://purl.uniprot.org/uniprot/T2GF76 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/1121448:DGI_RS14235 ^@ http://purl.uniprot.org/uniprot/T2GFS7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS04210 ^@ http://purl.uniprot.org/uniprot/T2G900 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1121448:DGI_RS06695 ^@ http://purl.uniprot.org/uniprot/T2GAR0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/1121448:DGI_RS03205 ^@ http://purl.uniprot.org/uniprot/T2G9L4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family. http://togogenome.org/gene/1121448:DGI_RS00170 ^@ http://purl.uniprot.org/uniprot/T2G705 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/1121448:DGI_RS10880 ^@ http://purl.uniprot.org/uniprot/T2GCV4 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1121448:DGI_RS10555 ^@ http://purl.uniprot.org/uniprot/T2GD71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1121448:DGI_RS11695 ^@ http://purl.uniprot.org/uniprot/T2GDM7 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1121448:DGI_RS07360 ^@ http://purl.uniprot.org/uniprot/T2GAT0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1121448:DGI_RS11800 ^@ http://purl.uniprot.org/uniprot/T2GCJ4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1121448:DGI_RS15900 ^@ http://purl.uniprot.org/uniprot/T2GFZ5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/1121448:DGI_RS08240 ^@ http://purl.uniprot.org/uniprot/T2GAH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1121448:DGI_RS08945 ^@ http://purl.uniprot.org/uniprot/T2GAV7 ^@ Function|||Similarity ^@ Belongs to the ferredoxin thioredoxin reductase beta subunit family.|||Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin. http://togogenome.org/gene/1121448:DGI_RS14555 ^@ http://purl.uniprot.org/uniprot/T2GF96 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1121448:DGI_RS09935 ^@ http://purl.uniprot.org/uniprot/T2GDD0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1121448:DGI_RS14825 ^@ http://purl.uniprot.org/uniprot/T2GF41 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1121448:DGI_RS13060 ^@ http://purl.uniprot.org/uniprot/T2GE72 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1121448:DGI_RS17615 ^@ http://purl.uniprot.org/uniprot/T2GGA7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1121448:DGI_RS12540 ^@ http://purl.uniprot.org/uniprot/T2GCZ3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1121448:DGI_RS04220 ^@ http://purl.uniprot.org/uniprot/T2G860 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1121448:DGI_RS00150 ^@ http://purl.uniprot.org/uniprot/T2G5W2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS11340 ^@ http://purl.uniprot.org/uniprot/T2GDL4 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS16430 ^@ http://purl.uniprot.org/uniprot/T2GGI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS02490 ^@ http://purl.uniprot.org/uniprot/T2G8G5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutB family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/1121448:DGI_RS12670 ^@ http://purl.uniprot.org/uniprot/T2GD17 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.|||Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Homohexamer. Dimer of a homotrimer.|||Purine nucleoside phosphorylase involved in purine salvage. http://togogenome.org/gene/1121448:DGI_RS08030 ^@ http://purl.uniprot.org/uniprot/T2GBI7 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/1121448:DGI_RS12880 ^@ http://purl.uniprot.org/uniprot/T2GF13 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/1121448:DGI_RS04910 ^@ http://purl.uniprot.org/uniprot/T2G8I7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS11595 ^@ http://purl.uniprot.org/uniprot/T2GD72 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1121448:DGI_RS08805 ^@ http://purl.uniprot.org/uniprot/T2GCQ3 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/1121448:DGI_RS07415 ^@ http://purl.uniprot.org/uniprot/T2G9Y3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS14535 ^@ http://purl.uniprot.org/uniprot/T2GE31 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS08375 ^@ http://purl.uniprot.org/uniprot/T2GBL4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1121448:DGI_RS14415 ^@ http://purl.uniprot.org/uniprot/T2GFB7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/1121448:DGI_RS08145 ^@ http://purl.uniprot.org/uniprot/T2GBN0 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1121448:DGI_RS14460 ^@ http://purl.uniprot.org/uniprot/T2GE17 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/1121448:DGI_RS13040 ^@ http://purl.uniprot.org/uniprot/T2GEE9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1121448:DGI_RS01950 ^@ http://purl.uniprot.org/uniprot/T2G821 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS06705 ^@ http://purl.uniprot.org/uniprot/T2GAW4 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/1121448:DGI_RS07390 ^@ http://purl.uniprot.org/uniprot/T2G9X8 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1121448:DGI_RS13090 ^@ http://purl.uniprot.org/uniprot/T2GEJ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1121448:DGI_RS15665 ^@ http://purl.uniprot.org/uniprot/T2GG00 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1121448:DGI_RS04015 ^@ http://purl.uniprot.org/uniprot/T2G984 ^@ Similarity ^@ Belongs to the pseudouridine synthase RluA family. http://togogenome.org/gene/1121448:DGI_RS08045 ^@ http://purl.uniprot.org/uniprot/T2GCA2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1121448:DGI_RS03270 ^@ http://purl.uniprot.org/uniprot/T2G7P2 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1121448:DGI_RS07975 ^@ http://purl.uniprot.org/uniprot/T2GB56 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1121448:DGI_RS09900 ^@ http://purl.uniprot.org/uniprot/T2GBF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS16180 ^@ http://purl.uniprot.org/uniprot/T2GG77 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS13110 ^@ http://purl.uniprot.org/uniprot/T2GE82 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1121448:DGI_RS00030 ^@ http://purl.uniprot.org/uniprot/T2G7S8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1121448:DGI_RS12595 ^@ http://purl.uniprot.org/uniprot/T2GD02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/1121448:DGI_RS14005 ^@ http://purl.uniprot.org/uniprot/T2GF50 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/1121448:DGI_RS10160 ^@ http://purl.uniprot.org/uniprot/T2GCE1 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1121448:DGI_RS06245 ^@ http://purl.uniprot.org/uniprot/T2GB97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/1121448:DGI_RS09755 ^@ http://purl.uniprot.org/uniprot/T2GBC3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1121448:DGI_RS10670 ^@ http://purl.uniprot.org/uniprot/T2GD46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS16860 ^@ http://purl.uniprot.org/uniprot/T2G903 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1121448:DGI_RS09970 ^@ http://purl.uniprot.org/uniprot/T2GCA6 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1121448:DGI_RS12080 ^@ http://purl.uniprot.org/uniprot/T2GEK5 ^@ Function|||Similarity ^@ Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.|||Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/1121448:DGI_RS07670 ^@ http://purl.uniprot.org/uniprot/T2GBA9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/1121448:DGI_RS01730 ^@ http://purl.uniprot.org/uniprot/T2G8Q6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1121448:DGI_RS04410 ^@ http://purl.uniprot.org/uniprot/T2GA69 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1121448:DGI_RS03180 ^@ http://purl.uniprot.org/uniprot/T2G9K4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/1121448:DGI_RS17175 ^@ http://purl.uniprot.org/uniprot/T2GC39 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/1121448:DGI_RS10125 ^@ http://purl.uniprot.org/uniprot/T2GBK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS04060 ^@ http://purl.uniprot.org/uniprot/T2G8X3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1121448:DGI_RS00630 ^@ http://purl.uniprot.org/uniprot/T2G876 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1121448:DGI_RS15065 ^@ http://purl.uniprot.org/uniprot/T2GFM9 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1121448:DGI_RS10765 ^@ http://purl.uniprot.org/uniprot/T2GC02 ^@ Subunit ^@ Heterodimer of a large and a small subunit. http://togogenome.org/gene/1121448:DGI_RS00365 ^@ http://purl.uniprot.org/uniprot/T2G610 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. http://togogenome.org/gene/1121448:DGI_RS07385 ^@ http://purl.uniprot.org/uniprot/T2GB49 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/1121448:DGI_RS08900 ^@ http://purl.uniprot.org/uniprot/T2GC57 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1121448:DGI_RS16665 ^@ http://purl.uniprot.org/uniprot/T2GGB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP G family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS12410 ^@ http://purl.uniprot.org/uniprot/T2GE18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS15505 ^@ http://purl.uniprot.org/uniprot/T2GEL0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS11165 ^@ http://purl.uniprot.org/uniprot/T2GDC5 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/1121448:DGI_RS01595 ^@ http://purl.uniprot.org/uniprot/T2G8N7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/1121448:DGI_RS02465 ^@ http://purl.uniprot.org/uniprot/T2G8G0 ^@ Similarity|||Subunit ^@ Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1121448:DGI_RS08410 ^@ http://purl.uniprot.org/uniprot/T2GC22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/1121448:DGI_RS06055 ^@ http://purl.uniprot.org/uniprot/T2G974 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/1121448:DGI_RS02555 ^@ http://purl.uniprot.org/uniprot/T2G834 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS12580 ^@ http://purl.uniprot.org/uniprot/T2GEU9 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1121448:DGI_RS13225 ^@ http://purl.uniprot.org/uniprot/T2GEQ2 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/1121448:DGI_RS02025 ^@ http://purl.uniprot.org/uniprot/T2G874 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS11635 ^@ http://purl.uniprot.org/uniprot/T2GDS0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS16105 ^@ http://purl.uniprot.org/uniprot/T2GG66 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1121448:DGI_RS12740 ^@ http://purl.uniprot.org/uniprot/T2GE75 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1121448:DGI_RS11475 ^@ http://purl.uniprot.org/uniprot/T2GD53 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1121448:DGI_RS04140 ^@ http://purl.uniprot.org/uniprot/T2G9A7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS03555 ^@ http://purl.uniprot.org/uniprot/T2G8P0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS05385 ^@ http://purl.uniprot.org/uniprot/T2GAQ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1121448:DGI_RS13390 ^@ http://purl.uniprot.org/uniprot/T2GEN3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/1121448:DGI_RS12985 ^@ http://purl.uniprot.org/uniprot/T2GE15 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1121448:DGI_RS13435 ^@ http://purl.uniprot.org/uniprot/T2GEE0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1121448:DGI_RS07620 ^@ http://purl.uniprot.org/uniprot/T2GAY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS14735 ^@ http://purl.uniprot.org/uniprot/T2GE63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane http://togogenome.org/gene/1121448:DGI_RS06880 ^@ http://purl.uniprot.org/uniprot/T2GAZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS10140 ^@ http://purl.uniprot.org/uniprot/T2GCD8 ^@ Similarity ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family. http://togogenome.org/gene/1121448:DGI_RS00455 ^@ http://purl.uniprot.org/uniprot/T2G820 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS10260 ^@ http://purl.uniprot.org/uniprot/T2GCG3 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/1121448:DGI_RS03130 ^@ http://purl.uniprot.org/uniprot/T2G9J4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1121448:DGI_RS02375 ^@ http://purl.uniprot.org/uniprot/T2G8A2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/1121448:DGI_RS00945 ^@ http://purl.uniprot.org/uniprot/T2G8D2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1121448:DGI_RS12350 ^@ http://purl.uniprot.org/uniprot/T2GEQ0 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1121448:DGI_RS05250 ^@ http://purl.uniprot.org/uniprot/T2GA17 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/1121448:DGI_RS07935 ^@ http://purl.uniprot.org/uniprot/T2GA91 ^@ Cofactor ^@ Binds 4 heme c groups covalently per monomer. http://togogenome.org/gene/1121448:DGI_RS15405 ^@ http://purl.uniprot.org/uniprot/T2GFF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS12375 ^@ http://purl.uniprot.org/uniprot/T2GEQ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS06825 ^@ http://purl.uniprot.org/uniprot/T2G9L7 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/1121448:DGI_RS01075 ^@ http://purl.uniprot.org/uniprot/T2G8F1 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1121448:DGI_RS13210 ^@ http://purl.uniprot.org/uniprot/T2GE99 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. http://togogenome.org/gene/1121448:DGI_RS07110 ^@ http://purl.uniprot.org/uniprot/T2GAN0 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1121448:DGI_RS14010 ^@ http://purl.uniprot.org/uniprot/T2GFP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS16005 ^@ http://purl.uniprot.org/uniprot/T2GF02 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1121448:DGI_RS07205 ^@ http://purl.uniprot.org/uniprot/T2GAQ1 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/1121448:DGI_RS03125 ^@ http://purl.uniprot.org/uniprot/T2G8X0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1121448:DGI_RS10370 ^@ http://purl.uniprot.org/uniprot/T2GBP7 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/1121448:DGI_RS10330 ^@ http://purl.uniprot.org/uniprot/T2GDM5 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1121448:DGI_RS02685 ^@ http://purl.uniprot.org/uniprot/T2G981 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1121448:DGI_RS12995 ^@ http://purl.uniprot.org/uniprot/T2GD80 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1121448:DGI_RS05425 ^@ http://purl.uniprot.org/uniprot/T2GA53 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS12970 ^@ http://purl.uniprot.org/uniprot/T2GD74 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1121448:DGI_RS06945 ^@ http://purl.uniprot.org/uniprot/T2GAV8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS13095 ^@ http://purl.uniprot.org/uniprot/T2GDC7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1121448:DGI_RS15690 ^@ http://purl.uniprot.org/uniprot/T2GG04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1121448:DGI_RS03800 ^@ http://purl.uniprot.org/uniprot/T2G997 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/1121448:DGI_RS11735 ^@ http://purl.uniprot.org/uniprot/T2GEF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS01400 ^@ http://purl.uniprot.org/uniprot/T2G7W6 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1121448:DGI_RS10740 ^@ http://purl.uniprot.org/uniprot/T2GBZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS03225 ^@ http://purl.uniprot.org/uniprot/T2G8Y9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS16360 ^@ http://purl.uniprot.org/uniprot/T2GFX4 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/1121448:DGI_RS11560 ^@ http://purl.uniprot.org/uniprot/T2GDQ6 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1121448:DGI_RS01630 ^@ http://purl.uniprot.org/uniprot/T2G7K3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS07575 ^@ http://purl.uniprot.org/uniprot/Q01095|||http://purl.uniprot.org/uniprot/T2GB90 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Electron-transfer proteins that function in various electron transport systems in microorganisms. Functionally interchangeable with ferredoxin.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/1121448:DGI_RS14835 ^@ http://purl.uniprot.org/uniprot/T2GE83 ^@ Caution|||Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS14450 ^@ http://purl.uniprot.org/uniprot/T2GEW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1121448:DGI_RS01650 ^@ http://purl.uniprot.org/uniprot/T2G8P6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1121448:DGI_RS10090 ^@ http://purl.uniprot.org/uniprot/T2GDG5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1121448:DGI_RS13020 ^@ http://purl.uniprot.org/uniprot/T2GD85 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1121448:DGI_RS04050 ^@ http://purl.uniprot.org/uniprot/T2G9E5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS08280 ^@ http://purl.uniprot.org/uniprot/T2GCG6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1121448:DGI_RS13045 ^@ http://purl.uniprot.org/uniprot/T2GDA3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1121448:DGI_RS15525 ^@ http://purl.uniprot.org/uniprot/T2GFT0 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1121448:DGI_RS06935 ^@ http://purl.uniprot.org/uniprot/T2GBL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1121448:DGI_RS08725 ^@ http://purl.uniprot.org/uniprot/T2GC22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/1121448:DGI_RS14310 ^@ http://purl.uniprot.org/uniprot/T2GFT7 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1121448:DGI_RS14230 ^@ http://purl.uniprot.org/uniprot/T2GF84 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/1121448:DGI_RS02775 ^@ http://purl.uniprot.org/uniprot/T2G7B5 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1121448:DGI_RS13380 ^@ http://purl.uniprot.org/uniprot/T2GFE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1121448:DGI_RS08640 ^@ http://purl.uniprot.org/uniprot/T2GAP8 ^@ Function ^@ Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. http://togogenome.org/gene/1121448:DGI_RS09145 ^@ http://purl.uniprot.org/uniprot/T2GCW8 ^@ Function ^@ The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. http://togogenome.org/gene/1121448:DGI_RS05755 ^@ http://purl.uniprot.org/uniprot/T2GAD8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1121448:DGI_RS14015 ^@ http://purl.uniprot.org/uniprot/T2GEN1 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS03150 ^@ http://purl.uniprot.org/uniprot/T2G8X6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase B chain family.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Membrane http://togogenome.org/gene/1121448:DGI_RS02605 ^@ http://purl.uniprot.org/uniprot/T2G843 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS14445 ^@ http://purl.uniprot.org/uniprot/T2GFV5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1121448:DGI_RS06725 ^@ http://purl.uniprot.org/uniprot/T2G9K0 ^@ Cofactor|||Similarity ^@ Belongs to the ApbE family.|||Magnesium. Can also use manganese. http://togogenome.org/gene/1121448:DGI_RS12930 ^@ http://purl.uniprot.org/uniprot/T2GF25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1121448:DGI_RS02480 ^@ http://purl.uniprot.org/uniprot/T2G8C4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS16305 ^@ http://purl.uniprot.org/uniprot/T2GGH9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/1121448:DGI_RS10590 ^@ http://purl.uniprot.org/uniprot/T2GCQ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/1121448:DGI_RS11980 ^@ http://purl.uniprot.org/uniprot/T2GDY5 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1121448:DGI_RS11490 ^@ http://purl.uniprot.org/uniprot/T2GDP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/1121448:DGI_RS13035 ^@ http://purl.uniprot.org/uniprot/T2GE36 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1121448:DGI_RS12450 ^@ http://purl.uniprot.org/uniprot/T2GES0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/1121448:DGI_RS14145 ^@ http://purl.uniprot.org/uniprot/T2GF27 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/1121448:DGI_RS04725 ^@ http://purl.uniprot.org/uniprot/T2G9L0 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/1121448:DGI_RS13410 ^@ http://purl.uniprot.org/uniprot/T2GED6 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1121448:DGI_RS01190 ^@ http://purl.uniprot.org/uniprot/T2G6I4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1121448:DGI_RS12900 ^@ http://purl.uniprot.org/uniprot/T2GEG4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1121448:DGI_RS00450 ^@ http://purl.uniprot.org/uniprot/T2G7C5 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1121448:DGI_RS16055 ^@ http://purl.uniprot.org/uniprot/T2GF12 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1121448:DGI_RS03390 ^@ http://purl.uniprot.org/uniprot/T2G8L0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS06530 ^@ http://purl.uniprot.org/uniprot/T2G9G6 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/1121448:DGI_RS04750 ^@ http://purl.uniprot.org/uniprot/T2G9L5 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/1121448:DGI_RS07090 ^@ http://purl.uniprot.org/uniprot/T2GAY4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1121448:DGI_RS03395 ^@ http://purl.uniprot.org/uniprot/T2G8W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS02470 ^@ http://purl.uniprot.org/uniprot/T2G937 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1121448:DGI_RS02105 ^@ http://purl.uniprot.org/uniprot/T2G8X1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS07045 ^@ http://purl.uniprot.org/uniprot/T2GAX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS15625 ^@ http://purl.uniprot.org/uniprot/T2GFM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1121448:DGI_RS08645 ^@ http://purl.uniprot.org/uniprot/T2GC08 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/1121448:DGI_RS08290 ^@ http://purl.uniprot.org/uniprot/T2GBQ2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1121448:DGI_RS12380 ^@ http://purl.uniprot.org/uniprot/T2GDN4 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1121448:DGI_RS02040 ^@ http://purl.uniprot.org/uniprot/T2G839 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/1121448:DGI_RS12425 ^@ http://purl.uniprot.org/uniprot/T2GER4 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/1121448:DGI_RS02875 ^@ http://purl.uniprot.org/uniprot/T2G7D8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1121448:DGI_RS03210 ^@ http://purl.uniprot.org/uniprot/T2G8I0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS06680 ^@ http://purl.uniprot.org/uniprot/T2GAW2 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/1121448:DGI_RS05935 ^@ http://purl.uniprot.org/uniprot/T2GAG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS11780 ^@ http://purl.uniprot.org/uniprot/T2GDU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS08855 ^@ http://purl.uniprot.org/uniprot/T2GCR2 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1121448:DGI_RS10770 ^@ http://purl.uniprot.org/uniprot/T2GDA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS03990 ^@ http://purl.uniprot.org/uniprot/T2G980 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS03810 ^@ http://purl.uniprot.org/uniprot/T2G8T0 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1121448:DGI_RS00680 ^@ http://purl.uniprot.org/uniprot/T2G752 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1121448:DGI_RS12635 ^@ http://purl.uniprot.org/uniprot/T2GDT9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1121448:DGI_RS04025 ^@ http://purl.uniprot.org/uniprot/T2G9E0 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1121448:DGI_RS14865 ^@ http://purl.uniprot.org/uniprot/T2GFF5 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1121448:DGI_RS03120 ^@ http://purl.uniprot.org/uniprot/T2G7K9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1121448:DGI_RS11515 ^@ http://purl.uniprot.org/uniprot/T2GDP5 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/1121448:DGI_RS07820 ^@ http://purl.uniprot.org/uniprot/T2GA70 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1121448:DGI_RS05545 ^@ http://purl.uniprot.org/uniprot/T2GAU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS00310 ^@ http://purl.uniprot.org/uniprot/T2G6U7 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/1121448:DGI_RS10105 ^@ http://purl.uniprot.org/uniprot/T2GBJ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS13220 ^@ http://purl.uniprot.org/uniprot/T2GDF0 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/1121448:DGI_RS15155 ^@ http://purl.uniprot.org/uniprot/T2GEE2 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1121448:DGI_RS05055 ^@ http://purl.uniprot.org/uniprot/T2G9S7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS14715 ^@ http://purl.uniprot.org/uniprot/T2GFH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1121448:DGI_RS05570 ^@ http://purl.uniprot.org/uniprot/T2G9T0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS10080 ^@ http://purl.uniprot.org/uniprot/T2GBJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Belongs to the TatB family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/1121448:DGI_RS11875 ^@ http://purl.uniprot.org/uniprot/T2GCL0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/1121448:DGI_RS00585 ^@ http://purl.uniprot.org/uniprot/T2G731 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1121448:DGI_RS01995 ^@ http://purl.uniprot.org/uniprot/T2G7S1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS06375 ^@ http://purl.uniprot.org/uniprot/T2GAJ5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS13055 ^@ http://purl.uniprot.org/uniprot/T2GF91 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1121448:DGI_RS10600 ^@ http://purl.uniprot.org/uniprot/T2GBX1 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1121448:DGI_RS03140 ^@ http://purl.uniprot.org/uniprot/T2G8S8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1121448:DGI_RS16175 ^@ http://purl.uniprot.org/uniprot/T2GF36 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1121448:DGI_RS13985 ^@ http://purl.uniprot.org/uniprot/T2GFP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1121448:DGI_RS13155 ^@ http://purl.uniprot.org/uniprot/T2GFA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS02835 ^@ http://purl.uniprot.org/uniprot/T2G9B5 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS06415 ^@ http://purl.uniprot.org/uniprot/T2GA98 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS14120 ^@ http://purl.uniprot.org/uniprot/T2GF22 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M15D family.|||Binds 1 zinc ion per subunit.|||Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. http://togogenome.org/gene/1121448:DGI_RS15745 ^@ http://purl.uniprot.org/uniprot/T2GGF0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1121448:DGI_RS17050 ^@ http://purl.uniprot.org/uniprot/T2GAN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS15870 ^@ http://purl.uniprot.org/uniprot/T2GFQ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm|||In the C-terminal section; belongs to the AccA family.|||In the N-terminal section; belongs to the AccD/PCCB family. http://togogenome.org/gene/1121448:DGI_RS01555 ^@ http://purl.uniprot.org/uniprot/T2G6P8 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1121448:DGI_RS01170 ^@ http://purl.uniprot.org/uniprot/T2G7S4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS00485 ^@ http://purl.uniprot.org/uniprot/T2G6Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS12810 ^@ http://purl.uniprot.org/uniprot/T2GE92 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1121448:DGI_RS02380 ^@ http://purl.uniprot.org/uniprot/T2G738 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1121448:DGI_RS06895 ^@ http://purl.uniprot.org/uniprot/T2GAU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS02090 ^@ http://purl.uniprot.org/uniprot/T2G849 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS05510 ^@ http://purl.uniprot.org/uniprot/T2G9R4 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/1121448:DGI_RS08190 ^@ http://purl.uniprot.org/uniprot/T2GBP0 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1121448:DGI_RS00400 ^@ http://purl.uniprot.org/uniprot/T2G7B2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS08840 ^@ http://purl.uniprot.org/uniprot/T2GBZ1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1121448:DGI_RS03460 ^@ http://purl.uniprot.org/uniprot/T2G8M2 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1121448:DGI_RS14410 ^@ http://purl.uniprot.org/uniprot/T2GE08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1121448:DGI_RS08635 ^@ http://purl.uniprot.org/uniprot/T2GBV6 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1121448:DGI_RS02385 ^@ http://purl.uniprot.org/uniprot/T2G8E4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1121448:DGI_RS05185 ^@ http://purl.uniprot.org/uniprot/T2G9J3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1121448:DGI_RS01390 ^@ http://purl.uniprot.org/uniprot/T2G7Q6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/1121448:DGI_RS13375 ^@ http://purl.uniprot.org/uniprot/T2GES8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS02000 ^@ http://purl.uniprot.org/uniprot/T2G831 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1121448:DGI_RS08155 ^@ http://purl.uniprot.org/uniprot/T2GBS3 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/1121448:DGI_RS04235 ^@ http://purl.uniprot.org/uniprot/T2G905 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliN/MopA/SpaO family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS06950 ^@ http://purl.uniprot.org/uniprot/T2G9P5 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1121448:DGI_RS14540 ^@ http://purl.uniprot.org/uniprot/T2GFE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS05530 ^@ http://purl.uniprot.org/uniprot/T2G9S0 ^@ Similarity ^@ Belongs to the rubredoxin family. http://togogenome.org/gene/1121448:DGI_RS09130 ^@ http://purl.uniprot.org/uniprot/T2GAZ0 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/1121448:DGI_RS05410 ^@ http://purl.uniprot.org/uniprot/T2G9P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta sliding clamp family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS02455 ^@ http://purl.uniprot.org/uniprot/T2G8B8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family.|||Cell outer membrane|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1121448:DGI_RS03380 ^@ http://purl.uniprot.org/uniprot/T2G915 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS04655 ^@ http://purl.uniprot.org/uniprot/T2G8E1 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1121448:DGI_RS01575 ^@ http://purl.uniprot.org/uniprot/T2G7J2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1121448:DGI_RS13980 ^@ http://purl.uniprot.org/uniprot/T2GF47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1121448:DGI_RS13080 ^@ http://purl.uniprot.org/uniprot/T2GF95 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1121448:DGI_RS01610 ^@ http://purl.uniprot.org/uniprot/T2G7U9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1121448:DGI_RS10445 ^@ http://purl.uniprot.org/uniprot/T2GCX9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1121448:DGI_RS09880 ^@ http://purl.uniprot.org/uniprot/T2GCQ9 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1121448:DGI_RS05255 ^@ http://purl.uniprot.org/uniprot/T2GAN2 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/1121448:DGI_RS07875 ^@ http://purl.uniprot.org/uniprot/T2GB34 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/1121448:DGI_RS13460 ^@ http://purl.uniprot.org/uniprot/T2GEE4 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1121448:DGI_RS02840 ^@ http://purl.uniprot.org/uniprot/T2G891 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1121448:DGI_RS07010 ^@ http://purl.uniprot.org/uniprot/T2GBN3 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1121448:DGI_RS02870 ^@ http://purl.uniprot.org/uniprot/T2G8K3 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/1121448:DGI_RS16225 ^@ http://purl.uniprot.org/uniprot/T2GF45 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1121448:DGI_RS06735 ^@ http://purl.uniprot.org/uniprot/T2GBI4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1121448:DGI_RS16160 ^@ http://purl.uniprot.org/uniprot/T2GGH3 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/1121448:DGI_RS15930 ^@ http://purl.uniprot.org/uniprot/T2GEY7 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1121448:DGI_RS07365 ^@ http://purl.uniprot.org/uniprot/T2G9X3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1121448:DGI_RS02370 ^@ http://purl.uniprot.org/uniprot/T2G7Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/1121448:DGI_RS02675 ^@ http://purl.uniprot.org/uniprot/T2G794 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/1121448:DGI_RS09905 ^@ http://purl.uniprot.org/uniprot/T2GCR4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1121448:DGI_RS01675 ^@ http://purl.uniprot.org/uniprot/T2G8P9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1121448:DGI_RS11345 ^@ http://purl.uniprot.org/uniprot/T2GE76 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS15630 ^@ http://purl.uniprot.org/uniprot/T2GFV7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1121448:DGI_RS15210 ^@ http://purl.uniprot.org/uniprot/T2GEF3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/1121448:DGI_RS03540 ^@ http://purl.uniprot.org/uniprot/T2G7U2 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1121448:DGI_RS10290 ^@ http://purl.uniprot.org/uniprot/T2GCU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS10750 ^@ http://purl.uniprot.org/uniprot/T2GDX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1121448:DGI_RS02410 ^@ http://purl.uniprot.org/uniprot/T2G8F0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1121448:DGI_RS01645 ^@ http://purl.uniprot.org/uniprot/T2G805 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1121448:DGI_RS06625 ^@ http://purl.uniprot.org/uniprot/T2GAP6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1121448:DGI_RS16365 ^@ http://purl.uniprot.org/uniprot/T2GG69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/1121448:DGI_RS06730 ^@ http://purl.uniprot.org/uniprot/T2GAW7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1121448:DGI_RS06395 ^@ http://purl.uniprot.org/uniprot/T2GAK0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1121448:DGI_RS14800 ^@ http://purl.uniprot.org/uniprot/T2GF34 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1121448:DGI_RS06740 ^@ http://purl.uniprot.org/uniprot/T2GAF2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1121448:DGI_RS16280 ^@ http://purl.uniprot.org/uniprot/T2GG90 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/1121448:DGI_RS11680 ^@ http://purl.uniprot.org/uniprot/T2GCH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane