http://togogenome.org/gene/1550728:B5J99_RS14560 ^@ http://purl.uniprot.org/uniprot/A0A222X2U0 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1550728:B5J99_RS03030 ^@ http://purl.uniprot.org/uniprot/A0A222X4Y8 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1550728:B5J99_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A222X009 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1550728:B5J99_RS00420 ^@ http://purl.uniprot.org/uniprot/A0A222WWA5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1550728:B5J99_RS09490 ^@ http://purl.uniprot.org/uniprot/A0A222X0X2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS11805 ^@ http://purl.uniprot.org/uniprot/A0A222X205 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Binds a copper A center.|||Cell membrane|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/1550728:B5J99_RS07205 ^@ http://purl.uniprot.org/uniprot/A0A222WZQ8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS16600 ^@ http://purl.uniprot.org/uniprot/A0A222X204 ^@ Similarity ^@ Belongs to the CbbQ/NirQ/NorQ/GpvN family. http://togogenome.org/gene/1550728:B5J99_RS06820 ^@ http://purl.uniprot.org/uniprot/A0A222WZ29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1550728:B5J99_RS13805 ^@ http://purl.uniprot.org/uniprot/A0A222X208 ^@ Similarity ^@ Belongs to the ClpX chaperone family. HslU subfamily. http://togogenome.org/gene/1550728:B5J99_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A222WXC0 ^@ Caution|||Similarity ^@ Belongs to the UPF0391 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A222WWK5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1550728:B5J99_RS11810 ^@ http://purl.uniprot.org/uniprot/A0A222X1X2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS03010 ^@ http://purl.uniprot.org/uniprot/A0A222WX56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/1550728:B5J99_RS02715 ^@ http://purl.uniprot.org/uniprot/A0A222WVA1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS15250 ^@ http://purl.uniprot.org/uniprot/A0A222X3K6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1550728:B5J99_RS17395 ^@ http://purl.uniprot.org/uniprot/A0A222X2F8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1550728:B5J99_RS09080 ^@ http://purl.uniprot.org/uniprot/A0A222X050 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1550728:B5J99_RS06110 ^@ http://purl.uniprot.org/uniprot/A0A222WZ84 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1550728:B5J99_RS06975 ^@ http://purl.uniprot.org/uniprot/A0A222WZS4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/1550728:B5J99_RS06060 ^@ http://purl.uniprot.org/uniprot/A0A222WYJ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1550728:B5J99_RS09410 ^@ http://purl.uniprot.org/uniprot/A0A222X067 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1550728:B5J99_RS04895 ^@ http://purl.uniprot.org/uniprot/A0A222WXY4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1550728:B5J99_RS16520 ^@ http://purl.uniprot.org/uniprot/A0A222X4C2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1550728:B5J99_RS12255 ^@ http://purl.uniprot.org/uniprot/A0A222X2A4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1550728:B5J99_RS11395 ^@ http://purl.uniprot.org/uniprot/A0A222WZL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS12655 ^@ http://purl.uniprot.org/uniprot/A0A222X1F5 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/1550728:B5J99_RS03845 ^@ http://purl.uniprot.org/uniprot/A0A222WXG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/1550728:B5J99_RS10950 ^@ http://purl.uniprot.org/uniprot/A0A222X1H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS17480 ^@ http://purl.uniprot.org/uniprot/A0A222X496 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/1550728:B5J99_RS10090 ^@ http://purl.uniprot.org/uniprot/A0A222X0H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS10010 ^@ http://purl.uniprot.org/uniprot/A0A222WYU3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS09430 ^@ http://purl.uniprot.org/uniprot/A0A222X0A9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS13785 ^@ http://purl.uniprot.org/uniprot/A0A222X305 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1550728:B5J99_RS03855 ^@ http://purl.uniprot.org/uniprot/A0A222WVW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1550728:B5J99_RS00525 ^@ http://purl.uniprot.org/uniprot/A0A222WWK6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1550728:B5J99_RS17375 ^@ http://purl.uniprot.org/uniprot/A0A222X3Q1 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1550728:B5J99_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A222WW72 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.|||Homodimer. Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. http://togogenome.org/gene/1550728:B5J99_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A222WVQ8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1550728:B5J99_RS11685 ^@ http://purl.uniprot.org/uniprot/A0A222X200 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A222X0N7 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1550728:B5J99_RS13670 ^@ http://purl.uniprot.org/uniprot/A0A222X2E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/1550728:B5J99_RS05510 ^@ http://purl.uniprot.org/uniprot/A0A222WY88 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/1550728:B5J99_RS00370 ^@ http://purl.uniprot.org/uniprot/A0A222WW94 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1550728:B5J99_RS02090 ^@ http://purl.uniprot.org/uniprot/A0A222WUY8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1550728:B5J99_RS10830 ^@ http://purl.uniprot.org/uniprot/A0A222X0Z8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A222WVZ4 ^@ Function ^@ Multidrug efflux pump. http://togogenome.org/gene/1550728:B5J99_RS11140 ^@ http://purl.uniprot.org/uniprot/A0A222X142 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/1550728:B5J99_RS00835 ^@ http://purl.uniprot.org/uniprot/A0A222WW23 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1550728:B5J99_RS14205 ^@ http://purl.uniprot.org/uniprot/A0A222X277 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS11750 ^@ http://purl.uniprot.org/uniprot/A0A222X1Z5 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1550728:B5J99_RS10165 ^@ http://purl.uniprot.org/uniprot/A0A222WYY3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK. http://togogenome.org/gene/1550728:B5J99_RS07010 ^@ http://purl.uniprot.org/uniprot/A0A222WZ11 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1550728:B5J99_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A222WX64 ^@ Similarity ^@ Belongs to the type III secretion exporter family. http://togogenome.org/gene/1550728:B5J99_RS11105 ^@ http://purl.uniprot.org/uniprot/A0A222X0P4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1550728:B5J99_RS03410 ^@ http://purl.uniprot.org/uniprot/A0A222WVP2 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1550728:B5J99_RS18475 ^@ http://purl.uniprot.org/uniprot/A0A222X5A5 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1550728:B5J99_RS04910 ^@ http://purl.uniprot.org/uniprot/A0A222WYQ4 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1550728:B5J99_RS13440 ^@ http://purl.uniprot.org/uniprot/A0A222X2V8 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/1550728:B5J99_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A222WXW4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1550728:B5J99_RS10600 ^@ http://purl.uniprot.org/uniprot/A0A222X0F5 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/1550728:B5J99_RS10980 ^@ http://purl.uniprot.org/uniprot/A0A222X5A9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1550728:B5J99_RS01770 ^@ http://purl.uniprot.org/uniprot/A0A222WWD7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1550728:B5J99_RS09960 ^@ http://purl.uniprot.org/uniprot/A0A222X0J5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/1550728:B5J99_RS11130 ^@ http://purl.uniprot.org/uniprot/A0A222X5J3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1550728:B5J99_RS10840 ^@ http://purl.uniprot.org/uniprot/A0A222X1F7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS11350 ^@ http://purl.uniprot.org/uniprot/A0A222WZH9 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1550728:B5J99_RS06095 ^@ http://purl.uniprot.org/uniprot/A0A222WZA7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/1550728:B5J99_RS13590 ^@ http://purl.uniprot.org/uniprot/A0A222X295 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/1550728:B5J99_RS16240 ^@ http://purl.uniprot.org/uniprot/A0A222X432 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS16300 ^@ http://purl.uniprot.org/uniprot/A0A222X371 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/1550728:B5J99_RS09255 ^@ http://purl.uniprot.org/uniprot/A0A222X0V3 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/1550728:B5J99_RS13685 ^@ http://purl.uniprot.org/uniprot/A0A222X286 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1550728:B5J99_RS04370 ^@ http://purl.uniprot.org/uniprot/A0A222WW45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/1550728:B5J99_RS15655 ^@ http://purl.uniprot.org/uniprot/A0A222X3X3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/1550728:B5J99_RS17155 ^@ http://purl.uniprot.org/uniprot/A0A222X415 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1550728:B5J99_RS13905 ^@ http://purl.uniprot.org/uniprot/A0A222X334 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1550728:B5J99_RS03260 ^@ http://purl.uniprot.org/uniprot/A0A222WXV5 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1550728:B5J99_RS13580 ^@ http://purl.uniprot.org/uniprot/A0A222X1W6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1550728:B5J99_RS13915 ^@ http://purl.uniprot.org/uniprot/A0A222X323 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1550728:B5J99_RS12860 ^@ http://purl.uniprot.org/uniprot/A0A222X1Z2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1550728:B5J99_RS18470 ^@ http://purl.uniprot.org/uniprot/A0A222X2Y1 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1550728:B5J99_RS07460 ^@ http://purl.uniprot.org/uniprot/A0A222WZ99 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/1550728:B5J99_RS07355 ^@ http://purl.uniprot.org/uniprot/A0A222WXK5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1550728:B5J99_RS03105 ^@ http://purl.uniprot.org/uniprot/A0A222WVJ3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.|||Homodimer. http://togogenome.org/gene/1550728:B5J99_RS00425 ^@ http://purl.uniprot.org/uniprot/A0A222WVV3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1550728:B5J99_RS13470 ^@ http://purl.uniprot.org/uniprot/A0A222X0H3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1550728:B5J99_RS03920 ^@ http://purl.uniprot.org/uniprot/A0A222WVW7 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1550728:B5J99_RS12685 ^@ http://purl.uniprot.org/uniprot/A0A222X1V8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1550728:B5J99_RS02075 ^@ http://purl.uniprot.org/uniprot/A0A222WWB5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1550728:B5J99_RS01010 ^@ http://purl.uniprot.org/uniprot/A0A222WWT4 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1550728:B5J99_RS06195 ^@ http://purl.uniprot.org/uniprot/A0A222WX02 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/1550728:B5J99_RS11920 ^@ http://purl.uniprot.org/uniprot/A0A222X236 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1550728:B5J99_RS00225 ^@ http://purl.uniprot.org/uniprot/A0A222WU07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.|||Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.|||Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).|||Homodimer or monomer when oxidized or reduced, respectively.|||chloroplast http://togogenome.org/gene/1550728:B5J99_RS06800 ^@ http://purl.uniprot.org/uniprot/A0A222WYW8 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/1550728:B5J99_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A222WXG5 ^@ Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase class-III family. http://togogenome.org/gene/1550728:B5J99_RS11050 ^@ http://purl.uniprot.org/uniprot/A0A222WZB6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/1550728:B5J99_RS16490 ^@ http://purl.uniprot.org/uniprot/A0A222X3Q5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds the 23S rRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1550728:B5J99_RS15180 ^@ http://purl.uniprot.org/uniprot/A0A222X469 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS07345 ^@ http://purl.uniprot.org/uniprot/A0A222WXM3 ^@ Caution|||Cofactor|||Similarity ^@ Belongs to the WrbA family.|||Binds 1 FMN per monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS10615 ^@ http://purl.uniprot.org/uniprot/A0A222WZ61 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1550728:B5J99_RS02850 ^@ http://purl.uniprot.org/uniprot/A0A222X5I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS03075 ^@ http://purl.uniprot.org/uniprot/A0A222WXS5 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/1550728:B5J99_RS09485 ^@ http://purl.uniprot.org/uniprot/A0A222X0B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1550728:B5J99_RS04550 ^@ http://purl.uniprot.org/uniprot/A0A222WXS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS11935 ^@ http://purl.uniprot.org/uniprot/A0A222X1Z1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/1550728:B5J99_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A222X275 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1550728:B5J99_RS00335 ^@ http://purl.uniprot.org/uniprot/A0A222WVN1 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1550728:B5J99_RS11225 ^@ http://purl.uniprot.org/uniprot/A0A222WZD4 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1550728:B5J99_RS17100 ^@ http://purl.uniprot.org/uniprot/A0A222X281 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1550728:B5J99_RS12610 ^@ http://purl.uniprot.org/uniprot/A0A222X5K1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1550728:B5J99_RS10460 ^@ http://purl.uniprot.org/uniprot/A0A222X1G0 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1550728:B5J99_RS11000 ^@ http://purl.uniprot.org/uniprot/A0A222X3P3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS11445 ^@ http://purl.uniprot.org/uniprot/A0A222X179 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1550728:B5J99_RS16550 ^@ http://purl.uniprot.org/uniprot/A0A222X3R5 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1550728:B5J99_RS10400 ^@ http://purl.uniprot.org/uniprot/A0A222WZ14 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/1550728:B5J99_RS12525 ^@ http://purl.uniprot.org/uniprot/A0A222X062 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1550728:B5J99_RS08460 ^@ http://purl.uniprot.org/uniprot/A0A222X0E6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A222WZB5 ^@ Similarity ^@ Belongs to the UPF0311 family. http://togogenome.org/gene/1550728:B5J99_RS00505 ^@ http://purl.uniprot.org/uniprot/A0A222WU53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS14735 ^@ http://purl.uniprot.org/uniprot/A0A222X3B6 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/1550728:B5J99_RS02915 ^@ http://purl.uniprot.org/uniprot/A0A222WX13 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1550728:B5J99_RS13465 ^@ http://purl.uniprot.org/uniprot/A0A222X1U7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1550728:B5J99_RS09160 ^@ http://purl.uniprot.org/uniprot/A0A222WYH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1550728:B5J99_RS10455 ^@ http://purl.uniprot.org/uniprot/A0A222WZ17 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS00190 ^@ http://purl.uniprot.org/uniprot/A0A222WVT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the R-transferase family. Bpt subfamily.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. http://togogenome.org/gene/1550728:B5J99_RS14880 ^@ http://purl.uniprot.org/uniprot/A0A222X1C1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1550728:B5J99_RS16955 ^@ http://purl.uniprot.org/uniprot/A0A222X404 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1550728:B5J99_RS12215 ^@ http://purl.uniprot.org/uniprot/A0A222X240 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS03495 ^@ http://purl.uniprot.org/uniprot/A0A222WXZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1550728:B5J99_RS15585 ^@ http://purl.uniprot.org/uniprot/A0A222X3X0 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum|||Golgi apparatus|||Lysosome http://togogenome.org/gene/1550728:B5J99_RS09140 ^@ http://purl.uniprot.org/uniprot/A0A222X0Q9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1550728:B5J99_RS11500 ^@ http://purl.uniprot.org/uniprot/A0A222X163 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/1550728:B5J99_RS17645 ^@ http://purl.uniprot.org/uniprot/A0A222X5Z9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1550728:B5J99_RS00325 ^@ http://purl.uniprot.org/uniprot/A0A222WVI5 ^@ Cofactor|||Similarity ^@ Belongs to the RimK family.|||Binds 2 magnesium or manganese ions per subunit. http://togogenome.org/gene/1550728:B5J99_RS06090 ^@ http://purl.uniprot.org/uniprot/A0A222WWY2 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1550728:B5J99_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A222WW07 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1550728:B5J99_RS02980 ^@ http://purl.uniprot.org/uniprot/A0A222WWS3 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/1550728:B5J99_RS14335 ^@ http://purl.uniprot.org/uniprot/A0A222X298 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS10350 ^@ http://purl.uniprot.org/uniprot/A0A222X1E0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1550728:B5J99_RS00435 ^@ http://purl.uniprot.org/uniprot/A0A222WUB8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1550728:B5J99_RS09185 ^@ http://purl.uniprot.org/uniprot/A0A222WYF6 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/1550728:B5J99_RS10320 ^@ http://purl.uniprot.org/uniprot/A0A222X0L1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Cell inner membrane|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1550728:B5J99_RS12245 ^@ http://purl.uniprot.org/uniprot/A0A222X005 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS00510 ^@ http://purl.uniprot.org/uniprot/A0A222WU62 ^@ Function ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. http://togogenome.org/gene/1550728:B5J99_RS10845 ^@ http://purl.uniprot.org/uniprot/A0A222X0V2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS03240 ^@ http://purl.uniprot.org/uniprot/A0A222WVL3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS10835 ^@ http://purl.uniprot.org/uniprot/A0A222X1J6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS12040 ^@ http://purl.uniprot.org/uniprot/A0A222X244 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1550728:B5J99_RS11475 ^@ http://purl.uniprot.org/uniprot/A0A222X1V7 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/1550728:B5J99_RS13815 ^@ http://purl.uniprot.org/uniprot/A0A222X440 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/1550728:B5J99_RS13450 ^@ http://purl.uniprot.org/uniprot/A0A222X2T2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1550728:B5J99_RS10580 ^@ http://purl.uniprot.org/uniprot/A0A222X0V8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS15005 ^@ http://purl.uniprot.org/uniprot/A0A222X3L8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1550728:B5J99_RS08835 ^@ http://purl.uniprot.org/uniprot/A0A222WZL4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/1550728:B5J99_RS11790 ^@ http://purl.uniprot.org/uniprot/A0A222WZQ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/1550728:B5J99_RS05285 ^@ http://purl.uniprot.org/uniprot/A0A222WY71 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/1550728:B5J99_RS06845 ^@ http://purl.uniprot.org/uniprot/A0A222WXC5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/1550728:B5J99_RS18570 ^@ http://purl.uniprot.org/uniprot/A0A222X4A2 ^@ Similarity ^@ Belongs to the HpcH/HpaI aldolase family. http://togogenome.org/gene/1550728:B5J99_RS12115 ^@ http://purl.uniprot.org/uniprot/A0A222WZT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS11770 ^@ http://purl.uniprot.org/uniprot/A0A222X101 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/1550728:B5J99_RS11110 ^@ http://purl.uniprot.org/uniprot/A0A222WZC3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1550728:B5J99_RS02340 ^@ http://purl.uniprot.org/uniprot/A0A222WX81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1550728:B5J99_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A222WYB6 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1550728:B5J99_RS03245 ^@ http://purl.uniprot.org/uniprot/A0A222WVK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1550728:B5J99_RS18535 ^@ http://purl.uniprot.org/uniprot/A0A222X5B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS09295 ^@ http://purl.uniprot.org/uniprot/A0A222WYI0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1550728:B5J99_RS13520 ^@ http://purl.uniprot.org/uniprot/A0A222X2R3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1550728:B5J99_RS17105 ^@ http://purl.uniprot.org/uniprot/A0A222X406 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1550728:B5J99_RS06905 ^@ http://purl.uniprot.org/uniprot/A0A222WXD4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1550728:B5J99_RS10825 ^@ http://purl.uniprot.org/uniprot/A0A222X1M1 ^@ Function|||Similarity ^@ A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.|||Belongs to the bacterial AtpI family. http://togogenome.org/gene/1550728:B5J99_RS00400 ^@ http://purl.uniprot.org/uniprot/A0A222WU41 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1550728:B5J99_RS03880 ^@ http://purl.uniprot.org/uniprot/A0A222WXK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS00305 ^@ http://purl.uniprot.org/uniprot/A0A222WWG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS15860 ^@ http://purl.uniprot.org/uniprot/A0A222X3E0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1550728:B5J99_RS05090 ^@ http://purl.uniprot.org/uniprot/A0A222WY72 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1550728:B5J99_RS00365 ^@ http://purl.uniprot.org/uniprot/A0A222WWH1 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1550728:B5J99_RS16290 ^@ http://purl.uniprot.org/uniprot/A0A222X446 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1550728:B5J99_RS01805 ^@ http://purl.uniprot.org/uniprot/A0A222WWZ1 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. http://togogenome.org/gene/1550728:B5J99_RS04035 ^@ http://purl.uniprot.org/uniprot/A0A222WXN9 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1550728:B5J99_RS06120 ^@ http://purl.uniprot.org/uniprot/A0A222WYK9 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/1550728:B5J99_RS16960 ^@ http://purl.uniprot.org/uniprot/A0A222X4I6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1550728:B5J99_RS17165 ^@ http://purl.uniprot.org/uniprot/A0A222X2B9 ^@ Similarity|||Subunit ^@ Belongs to the P(II) protein family.|||Homotrimer. http://togogenome.org/gene/1550728:B5J99_RS10025 ^@ http://purl.uniprot.org/uniprot/A0A222X158 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1550728:B5J99_RS10710 ^@ http://purl.uniprot.org/uniprot/A0A222X1D8 ^@ Similarity ^@ Belongs to the RelE toxin family. http://togogenome.org/gene/1550728:B5J99_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A222X4M7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1550728:B5J99_RS03355 ^@ http://purl.uniprot.org/uniprot/A0A222WVM4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1550728:B5J99_RS16985 ^@ http://purl.uniprot.org/uniprot/A0A222X259 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1550728:B5J99_RS10270 ^@ http://purl.uniprot.org/uniprot/A0A222X095 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1550728:B5J99_RS16645 ^@ http://purl.uniprot.org/uniprot/A0A222X3D7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/1550728:B5J99_RS17795 ^@ http://purl.uniprot.org/uniprot/A0A222X5F7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1550728:B5J99_RS04000 ^@ http://purl.uniprot.org/uniprot/A0A222WXA0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1550728:B5J99_RS16415 ^@ http://purl.uniprot.org/uniprot/A0A222X3K0 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/1550728:B5J99_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A222WXQ2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1550728:B5J99_RS06930 ^@ http://purl.uniprot.org/uniprot/A0A222WZ49 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1550728:B5J99_RS07490 ^@ http://purl.uniprot.org/uniprot/A0A222WZV2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS08950 ^@ http://purl.uniprot.org/uniprot/A0A222X031 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1550728:B5J99_RS03735 ^@ http://purl.uniprot.org/uniprot/A0A222WXX7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS17085 ^@ http://purl.uniprot.org/uniprot/A0A222X4I5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1550728:B5J99_RS18365 ^@ http://purl.uniprot.org/uniprot/A0A222X4Q2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1550728:B5J99_RS02890 ^@ http://purl.uniprot.org/uniprot/A0A222WXQ6 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/1550728:B5J99_RS13445 ^@ http://purl.uniprot.org/uniprot/A0A222X2B1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS02675 ^@ http://purl.uniprot.org/uniprot/A0A222WXL3 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1550728:B5J99_RS01950 ^@ http://purl.uniprot.org/uniprot/A0A222WWK3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1550728:B5J99_RS09405 ^@ http://purl.uniprot.org/uniprot/A0A222WYL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1550728:B5J99_RS17090 ^@ http://purl.uniprot.org/uniprot/A0A222X3W2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1550728:B5J99_RS10420 ^@ http://purl.uniprot.org/uniprot/A0A222X1C8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1550728:B5J99_RS03345 ^@ http://purl.uniprot.org/uniprot/A0A222WX59 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/1550728:B5J99_RS14255 ^@ http://purl.uniprot.org/uniprot/A0A222X388 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1550728:B5J99_RS02745 ^@ http://purl.uniprot.org/uniprot/A0A222WWM9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Binds 1 copper ion per subunit, denoted as copper B.|||Binds 2 heme groups per subunit, denoted as high- and low-spin.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A222X0K0 ^@ Function|||PTM ^@ Binds 4 heme groups per subunit.|||The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor. http://togogenome.org/gene/1550728:B5J99_RS15410 ^@ http://purl.uniprot.org/uniprot/A0A222X3T8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS12690 ^@ http://purl.uniprot.org/uniprot/A0A222X5N5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/1550728:B5J99_RS08550 ^@ http://purl.uniprot.org/uniprot/A0A222WY59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the reaction center PufL/M/PsbA/D family.|||Cellular chromatophore membrane|||Membrane|||Reaction center is composed of four bacteriochlorophylls, two bacteriopheophytins, two ubiquinones, one iron, and highly hydrophobic polypeptide chains.|||The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. http://togogenome.org/gene/1550728:B5J99_RS01830 ^@ http://purl.uniprot.org/uniprot/A0A222WW77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/1550728:B5J99_RS11230 ^@ http://purl.uniprot.org/uniprot/A0A222X137 ^@ Similarity ^@ Belongs to the RelE toxin family. http://togogenome.org/gene/1550728:B5J99_RS10135 ^@ http://purl.uniprot.org/uniprot/A0A222X1A1 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. http://togogenome.org/gene/1550728:B5J99_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A222WYE3 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/1550728:B5J99_RS07620 ^@ http://purl.uniprot.org/uniprot/A0A222WZC9 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/1550728:B5J99_RS14845 ^@ http://purl.uniprot.org/uniprot/A0A222X3D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS07565 ^@ http://purl.uniprot.org/uniprot/A0A222WZB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1550728:B5J99_RS12520 ^@ http://purl.uniprot.org/uniprot/A0A222X5M5 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1550728:B5J99_RS17170 ^@ http://purl.uniprot.org/uniprot/A0A222X4P1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons.|||Oligomer of 12 subunits arranged in the form of two hexameric ring. http://togogenome.org/gene/1550728:B5J99_RS13545 ^@ http://purl.uniprot.org/uniprot/A0A222X0P5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS00405 ^@ http://purl.uniprot.org/uniprot/A0A222WWI0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1550728:B5J99_RS16380 ^@ http://purl.uniprot.org/uniprot/A0A222X1Z3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1550728:B5J99_RS16665 ^@ http://purl.uniprot.org/uniprot/A0A222X5W7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. http://togogenome.org/gene/1550728:B5J99_RS04010 ^@ http://purl.uniprot.org/uniprot/A0A222WVY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1550728:B5J99_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A222WZD7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1550728:B5J99_RS15365 ^@ http://purl.uniprot.org/uniprot/A0A222X3M9 ^@ Similarity ^@ Belongs to the SdhE FAD assembly factor family. http://togogenome.org/gene/1550728:B5J99_RS10625 ^@ http://purl.uniprot.org/uniprot/A0A222X615 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS12145 ^@ http://purl.uniprot.org/uniprot/A0A222X263 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/1550728:B5J99_RS16945 ^@ http://purl.uniprot.org/uniprot/A0A222X280 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1550728:B5J99_RS00300 ^@ http://purl.uniprot.org/uniprot/A0A222WVU9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS13490 ^@ http://purl.uniprot.org/uniprot/A0A222X0N5 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1550728:B5J99_RS11975 ^@ http://purl.uniprot.org/uniprot/A0A222WZT0 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1550728:B5J99_RS03860 ^@ http://purl.uniprot.org/uniprot/A0A222WXE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliQ/MopD/SpaQ family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS05290 ^@ http://purl.uniprot.org/uniprot/A0A222WXX4 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS11540 ^@ http://purl.uniprot.org/uniprot/A0A222X655 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/1550728:B5J99_RS00410 ^@ http://purl.uniprot.org/uniprot/A0A222WVX5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1550728:B5J99_RS03875 ^@ http://purl.uniprot.org/uniprot/A0A222WY80 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliN/MopA/SpaO family.|||Cell membrane|||FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS07625 ^@ http://purl.uniprot.org/uniprot/A0A222WZ33 ^@ Caution|||Similarity ^@ Belongs to the UPF0391 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS16375 ^@ http://purl.uniprot.org/uniprot/A0A222X225 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1550728:B5J99_RS14235 ^@ http://purl.uniprot.org/uniprot/A0A222X0X9 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/1550728:B5J99_RS06725 ^@ http://purl.uniprot.org/uniprot/A0A222WYV5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1550728:B5J99_RS10030 ^@ http://purl.uniprot.org/uniprot/A0A222X112 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1550728:B5J99_RS00255 ^@ http://purl.uniprot.org/uniprot/A0A222WVS3 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/1550728:B5J99_RS16950 ^@ http://purl.uniprot.org/uniprot/A0A222X4K0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1550728:B5J99_RS01025 ^@ http://purl.uniprot.org/uniprot/A0A222X329 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1550728:B5J99_RS06730 ^@ http://purl.uniprot.org/uniprot/A0A222WYL3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1550728:B5J99_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A222WWX1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1550728:B5J99_RS03445 ^@ http://purl.uniprot.org/uniprot/A0A222WX96 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1550728:B5J99_RS18480 ^@ http://purl.uniprot.org/uniprot/A0A222X4R8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1550728:B5J99_RS00415 ^@ http://purl.uniprot.org/uniprot/A0A222WWI1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1550728:B5J99_RS03980 ^@ http://purl.uniprot.org/uniprot/A0A222WXM9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1550728:B5J99_RS02525 ^@ http://purl.uniprot.org/uniprot/A0A222WWI8 ^@ Similarity ^@ Belongs to the SecB family. http://togogenome.org/gene/1550728:B5J99_RS07185 ^@ http://purl.uniprot.org/uniprot/A0A222WXH2 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/1550728:B5J99_RS10345 ^@ http://purl.uniprot.org/uniprot/A0A222WYZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1550728:B5J99_RS08840 ^@ http://purl.uniprot.org/uniprot/A0A222WYC1 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1550728:B5J99_RS10375 ^@ http://purl.uniprot.org/uniprot/A0A222X0M3 ^@ Similarity ^@ Belongs to the GST superfamily. NadH family. http://togogenome.org/gene/1550728:B5J99_RS06170 ^@ http://purl.uniprot.org/uniprot/A0A222X3D3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/1550728:B5J99_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A222WXM2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1550728:B5J99_RS10475 ^@ http://purl.uniprot.org/uniprot/A0A222X1D7 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1550728:B5J99_RS11340 ^@ http://purl.uniprot.org/uniprot/A0A222X156 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS03570 ^@ http://purl.uniprot.org/uniprot/A0A222WX94 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1550728:B5J99_RS17845 ^@ http://purl.uniprot.org/uniprot/A0A222X4W7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1550728:B5J99_RS17010 ^@ http://purl.uniprot.org/uniprot/A0A222X5V8 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family. http://togogenome.org/gene/1550728:B5J99_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A222X399 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b560 family.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/1550728:B5J99_RS07050 ^@ http://purl.uniprot.org/uniprot/A0A222WZ18 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1550728:B5J99_RS16815 ^@ http://purl.uniprot.org/uniprot/A0A222X4G6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1550728:B5J99_RS09085 ^@ http://purl.uniprot.org/uniprot/A0A222X0P8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/1550728:B5J99_RS06065 ^@ http://purl.uniprot.org/uniprot/A0A222X4P6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1550728:B5J99_RS00430 ^@ http://purl.uniprot.org/uniprot/A0A222WVK3 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1550728:B5J99_RS17490 ^@ http://purl.uniprot.org/uniprot/A0A222X4Q4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1550728:B5J99_RS10240 ^@ http://purl.uniprot.org/uniprot/A0A222WYY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS10935 ^@ http://purl.uniprot.org/uniprot/A0A222X1N9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/1550728:B5J99_RS13750 ^@ http://purl.uniprot.org/uniprot/A0A222X0L7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1550728:B5J99_RS14740 ^@ http://purl.uniprot.org/uniprot/A0A222X2Q7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS08455 ^@ http://purl.uniprot.org/uniprot/A0A222WZW3 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1550728:B5J99_RS12260 ^@ http://purl.uniprot.org/uniprot/A0A222X1P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS07135 ^@ http://purl.uniprot.org/uniprot/A0A222WXG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/1550728:B5J99_RS10740 ^@ http://purl.uniprot.org/uniprot/A0A222WZ78 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/1550728:B5J99_RS09155 ^@ http://purl.uniprot.org/uniprot/A0A222WZQ7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS15560 ^@ http://purl.uniprot.org/uniprot/A0A222X2V3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS16655 ^@ http://purl.uniprot.org/uniprot/A0A222X3T4 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1550728:B5J99_RS11720 ^@ http://purl.uniprot.org/uniprot/A0A222X1B9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1550728:B5J99_RS02565 ^@ http://purl.uniprot.org/uniprot/A0A222WXD1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the trans-sulfuration enzymes family. MetZ subfamily.|||Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.|||Homotetramer. http://togogenome.org/gene/1550728:B5J99_RS13715 ^@ http://purl.uniprot.org/uniprot/A0A222X0P2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1550728:B5J99_RS00390 ^@ http://purl.uniprot.org/uniprot/A0A222WVP3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1550728:B5J99_RS10265 ^@ http://purl.uniprot.org/uniprot/A0A222X0K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS16360 ^@ http://purl.uniprot.org/uniprot/A0A222X1W4 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1550728:B5J99_RS00460 ^@ http://purl.uniprot.org/uniprot/A0A222WWJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1550728:B5J99_RS16370 ^@ http://purl.uniprot.org/uniprot/A0A222X6C8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1550728:B5J99_RS03995 ^@ http://purl.uniprot.org/uniprot/A0A222WXJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1550728:B5J99_RS10410 ^@ http://purl.uniprot.org/uniprot/A0A222X1E9 ^@ Function|||Similarity ^@ Belongs to the AMP nucleosidase family.|||Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. http://togogenome.org/gene/1550728:B5J99_RS18330 ^@ http://purl.uniprot.org/uniprot/A0A222X461 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1550728:B5J99_RS05215 ^@ http://purl.uniprot.org/uniprot/A0A222WYN3 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/1550728:B5J99_RS01880 ^@ http://purl.uniprot.org/uniprot/A0A222WX00 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1550728:B5J99_RS09055 ^@ http://purl.uniprot.org/uniprot/A0A222X008 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GSP I family.|||Cell inner membrane|||Cleaved by prepilin peptidase.|||Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.|||Membrane|||Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. http://togogenome.org/gene/1550728:B5J99_RS07470 ^@ http://purl.uniprot.org/uniprot/A0A222WXM6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/1550728:B5J99_RS13675 ^@ http://purl.uniprot.org/uniprot/A0A222X2Y8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS06085 ^@ http://purl.uniprot.org/uniprot/A0A222WWY0 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1550728:B5J99_RS03885 ^@ http://purl.uniprot.org/uniprot/A0A222WY66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS08520 ^@ http://purl.uniprot.org/uniprot/A0A222X0C1 ^@ Similarity ^@ Belongs to the NifH/BchL/ChlL family. http://togogenome.org/gene/1550728:B5J99_RS00440 ^@ http://purl.uniprot.org/uniprot/A0A222WVQ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1550728:B5J99_RS10570 ^@ http://purl.uniprot.org/uniprot/A0A222WZ34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbI/VirB10 family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS16335 ^@ http://purl.uniprot.org/uniprot/A0A222X3Q7 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1550728:B5J99_RS15495 ^@ http://purl.uniprot.org/uniprot/A0A222X2U6 ^@ Similarity ^@ Belongs to the MreC family. http://togogenome.org/gene/1550728:B5J99_RS16445 ^@ http://purl.uniprot.org/uniprot/A0A222X201 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS02040 ^@ http://purl.uniprot.org/uniprot/A0A222WUY1 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1550728:B5J99_RS07030 ^@ http://purl.uniprot.org/uniprot/A0A222WZ69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Could be part of an ABC transporter complex.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS18485 ^@ http://purl.uniprot.org/uniprot/A0A222X5B3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1550728:B5J99_RS12135 ^@ http://purl.uniprot.org/uniprot/A0A222X284 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1550728:B5J99_RS11785 ^@ http://purl.uniprot.org/uniprot/A0A222WZS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/1550728:B5J99_RS05710 ^@ http://purl.uniprot.org/uniprot/A0A222WYD7 ^@ Function|||Similarity ^@ Belongs to the polysaccharide deacetylase family.|||Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts. http://togogenome.org/gene/1550728:B5J99_RS06860 ^@ http://purl.uniprot.org/uniprot/A0A222WXB2 ^@ Similarity|||Subunit ^@ Belongs to the P(II) protein family.|||Homotrimer. http://togogenome.org/gene/1550728:B5J99_RS12755 ^@ http://purl.uniprot.org/uniprot/A0A222X2D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS17140 ^@ http://purl.uniprot.org/uniprot/A0A222X3X2 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/1550728:B5J99_RS14665 ^@ http://purl.uniprot.org/uniprot/A0A222X3G4 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/1550728:B5J99_RS09650 ^@ http://purl.uniprot.org/uniprot/A0A222X123 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1550728:B5J99_RS04450 ^@ http://purl.uniprot.org/uniprot/A0A222X3H7 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1550728:B5J99_RS13390 ^@ http://purl.uniprot.org/uniprot/A0A222X2P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS03990 ^@ http://purl.uniprot.org/uniprot/A0A222WY27 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1550728:B5J99_RS11080 ^@ http://purl.uniprot.org/uniprot/A0A222X133 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS00475 ^@ http://purl.uniprot.org/uniprot/A0A222WWJ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1550728:B5J99_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A222X0S2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1550728:B5J99_RS09815 ^@ http://purl.uniprot.org/uniprot/A0A222WYS3 ^@ Similarity ^@ Belongs to the sterol desaturase family. http://togogenome.org/gene/1550728:B5J99_RS04055 ^@ http://purl.uniprot.org/uniprot/A0A222WXA9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1550728:B5J99_RS10550 ^@ http://purl.uniprot.org/uniprot/A0A222X0E5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1550728:B5J99_RS03915 ^@ http://purl.uniprot.org/uniprot/A0A222WVW9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/1550728:B5J99_RS17095 ^@ http://purl.uniprot.org/uniprot/A0A222X3K1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1550728:B5J99_RS09965 ^@ http://purl.uniprot.org/uniprot/A0A222X149 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/1550728:B5J99_RS16170 ^@ http://purl.uniprot.org/uniprot/A0A222X3M8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/1550728:B5J99_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A222WWN8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/1550728:B5J99_RS09095 ^@ http://purl.uniprot.org/uniprot/A0A222X000 ^@ Similarity ^@ Belongs to the thioredoxin family. DsbE subfamily. http://togogenome.org/gene/1550728:B5J99_RS07330 ^@ http://purl.uniprot.org/uniprot/A0A222WZ81 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1550728:B5J99_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A222WX29 ^@ Similarity ^@ Belongs to the lycopene cyclase family. http://togogenome.org/gene/1550728:B5J99_RS16435 ^@ http://purl.uniprot.org/uniprot/A0A222X231 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1550728:B5J99_RS14150 ^@ http://purl.uniprot.org/uniprot/A0A222X2G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A222WYA3 ^@ Function|||Similarity ^@ Belongs to the polysaccharide deacetylase family.|||Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts. http://togogenome.org/gene/1550728:B5J99_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A222X5J5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS01755 ^@ http://purl.uniprot.org/uniprot/A0A222WWG9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1550728:B5J99_RS17400 ^@ http://purl.uniprot.org/uniprot/A0A222X6F8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1550728:B5J99_RS12665 ^@ http://purl.uniprot.org/uniprot/A0A222X1T3 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1550728:B5J99_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A222WVE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS00105 ^@ http://purl.uniprot.org/uniprot/A0A222WVI4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1550728:B5J99_RS15580 ^@ http://purl.uniprot.org/uniprot/A0A222X1J7 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/1550728:B5J99_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A222WU50 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1550728:B5J99_RS13610 ^@ http://purl.uniprot.org/uniprot/A0A222X2D7 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1550728:B5J99_RS12195 ^@ http://purl.uniprot.org/uniprot/A0A222WZX2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1550728:B5J99_RS06290 ^@ http://purl.uniprot.org/uniprot/A0A222X586 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/1550728:B5J99_RS09180 ^@ http://purl.uniprot.org/uniprot/A0A222X5Z4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1550728:B5J99_RS09645 ^@ http://purl.uniprot.org/uniprot/A0A222WYN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/1550728:B5J99_RS14835 ^@ http://purl.uniprot.org/uniprot/A0A222X6D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS00985 ^@ http://purl.uniprot.org/uniprot/A0A222X4C8 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/1550728:B5J99_RS15400 ^@ http://purl.uniprot.org/uniprot/A0A222X1K5 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. http://togogenome.org/gene/1550728:B5J99_RS10960 ^@ http://purl.uniprot.org/uniprot/A0A222X0L8 ^@ Similarity ^@ Belongs to the UPF0335 family. http://togogenome.org/gene/1550728:B5J99_RS06020 ^@ http://purl.uniprot.org/uniprot/A0A222WYI7 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/1550728:B5J99_RS12305 ^@ http://purl.uniprot.org/uniprot/A0A222WZZ0 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/1550728:B5J99_RS04120 ^@ http://purl.uniprot.org/uniprot/A0A222WXJ3 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/1550728:B5J99_RS00350 ^@ http://purl.uniprot.org/uniprot/A0A222WWG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1550728:B5J99_RS09945 ^@ http://purl.uniprot.org/uniprot/A0A222WYT4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/1550728:B5J99_RS06900 ^@ http://purl.uniprot.org/uniprot/A0A222WYP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS04510 ^@ http://purl.uniprot.org/uniprot/A0A222WW62 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BchN/ChlN family.|||Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.|||Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.|||Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits. http://togogenome.org/gene/1550728:B5J99_RS16525 ^@ http://purl.uniprot.org/uniprot/A0A222X489 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1550728:B5J99_RS13455 ^@ http://purl.uniprot.org/uniprot/A0A222X2Q4 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1550728:B5J99_RS11215 ^@ http://purl.uniprot.org/uniprot/A0A222X0Q8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/1550728:B5J99_RS06080 ^@ http://purl.uniprot.org/uniprot/A0A222WYJ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1550728:B5J99_RS16500 ^@ http://purl.uniprot.org/uniprot/A0A222X210 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS00445 ^@ http://purl.uniprot.org/uniprot/A0A222WU44 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1550728:B5J99_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A222WYR1 ^@ Caution|||Function|||Similarity ^@ Belongs to the transcriptional regulatory CopG/NikR family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transcriptional regulator. http://togogenome.org/gene/1550728:B5J99_RS16485 ^@ http://purl.uniprot.org/uniprot/A0A222X1Y4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/1550728:B5J99_RS08535 ^@ http://purl.uniprot.org/uniprot/A0A222WY76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.|||Belongs to the antenna complex beta subunit family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1550728:B5J99_RS03975 ^@ http://purl.uniprot.org/uniprot/A0A222WY98 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. In Gram-negative bacteria, at least four rings, L, P, S and M are present, whereas Gram-positive bacteria lack the L and P rings. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF build up the proximal portion of the rod with about 6 subunits each. Rod assembly occurs by export via the flagellum-specific pathway of its constituent proteins and by their incorporation into the rod structure in the probable order of FlgB, FlgC, FlgF and FlgG. Another protein, FliE, also assembles onto the stable rod structure. http://togogenome.org/gene/1550728:B5J99_RS06840 ^@ http://purl.uniprot.org/uniprot/A0A222WYN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS08925 ^@ http://purl.uniprot.org/uniprot/A0A222WYC0 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/1550728:B5J99_RS05660 ^@ http://purl.uniprot.org/uniprot/A0A222WYC8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1550728:B5J99_RS13680 ^@ http://purl.uniprot.org/uniprot/A0A222X2U3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1550728:B5J99_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A222WYF3 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1550728:B5J99_RS11170 ^@ http://purl.uniprot.org/uniprot/A0A222WZD3 ^@ Similarity ^@ Belongs to the SDHAF4 family. http://togogenome.org/gene/1550728:B5J99_RS01940 ^@ http://purl.uniprot.org/uniprot/A0A222WX82 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1550728:B5J99_RS13140 ^@ http://purl.uniprot.org/uniprot/A0A222X2R1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1550728:B5J99_RS06785 ^@ http://purl.uniprot.org/uniprot/A0A222WYW5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1550728:B5J99_RS18375 ^@ http://purl.uniprot.org/uniprot/A0A222X557 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1550728:B5J99_RS04020 ^@ http://purl.uniprot.org/uniprot/A0A222WVY9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/1550728:B5J99_RS02000 ^@ http://purl.uniprot.org/uniprot/A0A222WX20 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/1550728:B5J99_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A222WXC8 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1550728:B5J99_RS08545 ^@ http://purl.uniprot.org/uniprot/A0A1S6KKD1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the reaction center PufL/M/PsbA/D family.|||Membrane|||The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. http://togogenome.org/gene/1550728:B5J99_RS09855 ^@ http://purl.uniprot.org/uniprot/A0A222X0D9 ^@ Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily. http://togogenome.org/gene/1550728:B5J99_RS06835 ^@ http://purl.uniprot.org/uniprot/A0A222WYX7 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1550728:B5J99_RS13635 ^@ http://purl.uniprot.org/uniprot/A0A222X0K3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1550728:B5J99_RS12680 ^@ http://purl.uniprot.org/uniprot/A0A222X2H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS15010 ^@ http://purl.uniprot.org/uniprot/A0A222X327 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1550728:B5J99_RS10585 ^@ http://purl.uniprot.org/uniprot/A0A222X1G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbL/VirB6 family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS12270 ^@ http://purl.uniprot.org/uniprot/A0A222X252 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/1550728:B5J99_RS07275 ^@ http://purl.uniprot.org/uniprot/A0A222WZ71 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1550728:B5J99_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A222WXZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/1550728:B5J99_RS09850 ^@ http://purl.uniprot.org/uniprot/A0A222X0Y2 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/1550728:B5J99_RS07070 ^@ http://purl.uniprot.org/uniprot/A0A222WXF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS08945 ^@ http://purl.uniprot.org/uniprot/A0A222X0Q6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1550728:B5J99_RS11800 ^@ http://purl.uniprot.org/uniprot/A0A222X1F6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS00375 ^@ http://purl.uniprot.org/uniprot/A0A222WVU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1550728:B5J99_RS10425 ^@ http://purl.uniprot.org/uniprot/A0A222X186 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/1550728:B5J99_RS03210 ^@ http://purl.uniprot.org/uniprot/A0A222WX60 ^@ Similarity ^@ Belongs to the GSP N family. http://togogenome.org/gene/1550728:B5J99_RS16470 ^@ http://purl.uniprot.org/uniprot/A0A222X478 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS02325 ^@ http://purl.uniprot.org/uniprot/A0A222WWU1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS00610 ^@ http://purl.uniprot.org/uniprot/A0A222WWD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1550728:B5J99_RS04995 ^@ http://purl.uniprot.org/uniprot/A0A222WXR9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b family.|||Binds 2 heme groups non-covalently.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/1550728:B5J99_RS12070 ^@ http://purl.uniprot.org/uniprot/A0A222X1H9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1550728:B5J99_RS14865 ^@ http://purl.uniprot.org/uniprot/A0A222X2X1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1550728:B5J99_RS02925 ^@ http://purl.uniprot.org/uniprot/A0A222WVE7 ^@ Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/1550728:B5J99_RS14525 ^@ http://purl.uniprot.org/uniprot/A0A222X5J1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS11035 ^@ http://purl.uniprot.org/uniprot/A0A222X0Y3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS04770 ^@ http://purl.uniprot.org/uniprot/A0A222WXW3 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1550728:B5J99_RS14295 ^@ http://purl.uniprot.org/uniprot/A0A222X3A1 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1550728:B5J99_RS00245 ^@ http://purl.uniprot.org/uniprot/A0A222WWF1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1550728:B5J99_RS05000 ^@ http://purl.uniprot.org/uniprot/A0A222WWF7 ^@ Cofactor ^@ Binds 1 heme c group covalently per subunit. http://togogenome.org/gene/1550728:B5J99_RS03720 ^@ http://purl.uniprot.org/uniprot/A0A222WXH8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1550728:B5J99_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A222WUC8 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1550728:B5J99_RS16480 ^@ http://purl.uniprot.org/uniprot/A0A222X3A5 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/1550728:B5J99_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A222WVD6 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/1550728:B5J99_RS02230 ^@ http://purl.uniprot.org/uniprot/A0A222WWP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS08830 ^@ http://purl.uniprot.org/uniprot/A0A222WZW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS02150 ^@ http://purl.uniprot.org/uniprot/A0A222WXD5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/1550728:B5J99_RS03150 ^@ http://purl.uniprot.org/uniprot/A0A222WWU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS16450 ^@ http://purl.uniprot.org/uniprot/A0A222X4C1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1550728:B5J99_RS11925 ^@ http://purl.uniprot.org/uniprot/A0A222X1H8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/1550728:B5J99_RS12780 ^@ http://purl.uniprot.org/uniprot/A0A222X0A4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS09550 ^@ http://purl.uniprot.org/uniprot/A0A222X0Y1 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein. http://togogenome.org/gene/1550728:B5J99_RS16460 ^@ http://purl.uniprot.org/uniprot/A0A222X3S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS04545 ^@ http://purl.uniprot.org/uniprot/A0A222WW84 ^@ Similarity ^@ Belongs to the geranylgeranyl reductase family. ChlP subfamily. http://togogenome.org/gene/1550728:B5J99_RS08540 ^@ http://purl.uniprot.org/uniprot/A0A222WZS9 ^@ Function|||Subcellular Location Annotation ^@ Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1550728:B5J99_RS04990 ^@ http://purl.uniprot.org/uniprot/A0A222WY11 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Rieske iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||The Rieske protein is a high potential 2Fe-2S protein.|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/1550728:B5J99_RS00465 ^@ http://purl.uniprot.org/uniprot/A0A222X5A6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1550728:B5J99_RS10125 ^@ http://purl.uniprot.org/uniprot/A0A222WYW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1550728:B5J99_RS10575 ^@ http://purl.uniprot.org/uniprot/A0A222X1I2 ^@ Similarity ^@ Belongs to the TrbG/VirB9 family. http://togogenome.org/gene/1550728:B5J99_RS13525 ^@ http://purl.uniprot.org/uniprot/A0A222X255 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/1550728:B5J99_RS13495 ^@ http://purl.uniprot.org/uniprot/A0A222X5Q3 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1550728:B5J99_RS04180 ^@ http://purl.uniprot.org/uniprot/A0A222X3G8 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS00470 ^@ http://purl.uniprot.org/uniprot/A0A222WVY4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1550728:B5J99_RS17200 ^@ http://purl.uniprot.org/uniprot/A0A222X3M1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1550728:B5J99_RS00605 ^@ http://purl.uniprot.org/uniprot/A0A222WWL5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1550728:B5J99_RS04090 ^@ http://purl.uniprot.org/uniprot/A0A222WYA6 ^@ Similarity ^@ Belongs to the UPF0053 family. Hemolysin C subfamily. http://togogenome.org/gene/1550728:B5J99_RS02180 ^@ http://purl.uniprot.org/uniprot/A0A222X357 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/1550728:B5J99_RS05535 ^@ http://purl.uniprot.org/uniprot/A0A222WYE4 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/1550728:B5J99_RS08590 ^@ http://purl.uniprot.org/uniprot/A0A222WZI2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1550728:B5J99_RS04395 ^@ http://purl.uniprot.org/uniprot/A0A222X4W9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/1550728:B5J99_RS14800 ^@ http://purl.uniprot.org/uniprot/A0A222X2H5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS09290 ^@ http://purl.uniprot.org/uniprot/A0A222X041 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1550728:B5J99_RS16330 ^@ http://purl.uniprot.org/uniprot/A0A222X4A0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1550728:B5J99_RS11820 ^@ http://purl.uniprot.org/uniprot/A0A222X110 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COX11/CtaG family.|||Cell inner membrane|||Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I. http://togogenome.org/gene/1550728:B5J99_RS11120 ^@ http://purl.uniprot.org/uniprot/A0A222WZE4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1550728:B5J99_RS00380 ^@ http://purl.uniprot.org/uniprot/A0A222WVJ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1550728:B5J99_RS04985 ^@ http://purl.uniprot.org/uniprot/A0A222WYJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/1550728:B5J99_RS16320 ^@ http://purl.uniprot.org/uniprot/A0A222X1Y0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1550728:B5J99_RS06210 ^@ http://purl.uniprot.org/uniprot/A0A222WYR9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS13650 ^@ http://purl.uniprot.org/uniprot/A0A222X0N4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1550728:B5J99_RS00490 ^@ http://purl.uniprot.org/uniprot/A0A222WVL7 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1550728:B5J99_RS00395 ^@ http://purl.uniprot.org/uniprot/A0A222WU30 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1550728:B5J99_RS15460 ^@ http://purl.uniprot.org/uniprot/A0A222X1I1 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1550728:B5J99_RS10325 ^@ http://purl.uniprot.org/uniprot/A0A222X0A3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1550728:B5J99_RS06015 ^@ http://purl.uniprot.org/uniprot/A0A222WWY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS15450 ^@ http://purl.uniprot.org/uniprot/A0A222X367 ^@ Similarity ^@ Belongs to the antibiotic N-acetyltransferase family. http://togogenome.org/gene/1550728:B5J99_RS09835 ^@ http://purl.uniprot.org/uniprot/A0A222X151 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1550728:B5J99_RS09280 ^@ http://purl.uniprot.org/uniprot/A0A222WZS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1550728:B5J99_RS07325 ^@ http://purl.uniprot.org/uniprot/A0A222WZS5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1550728:B5J99_RS09585 ^@ http://purl.uniprot.org/uniprot/A0A222WYN4 ^@ Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS10355 ^@ http://purl.uniprot.org/uniprot/A0A222X0S1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1550728:B5J99_RS03865 ^@ http://purl.uniprot.org/uniprot/A0A222WVW4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/1550728:B5J99_RS15500 ^@ http://purl.uniprot.org/uniprot/A0A222X1H3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS08465 ^@ http://purl.uniprot.org/uniprot/A0A222X0B1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1550728:B5J99_RS06775 ^@ http://purl.uniprot.org/uniprot/A0A222WZJ1 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/1550728:B5J99_RS17410 ^@ http://purl.uniprot.org/uniprot/A0A222X487 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/1550728:B5J99_RS13370 ^@ http://purl.uniprot.org/uniprot/A0A222X2U8 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/1550728:B5J99_RS10430 ^@ http://purl.uniprot.org/uniprot/A0A222X0N0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/1550728:B5J99_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A222WV16 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/1550728:B5J99_RS04030 ^@ http://purl.uniprot.org/uniprot/A0A222WYA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/1550728:B5J99_RS04325 ^@ http://purl.uniprot.org/uniprot/A0A222WYE7 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1550728:B5J99_RS01740 ^@ http://purl.uniprot.org/uniprot/A0A222WWJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination.