http://togogenome.org/gene/2562449:E4Z61_RS20805 ^@ http://purl.uniprot.org/uniprot/A0A4P7J6E7 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/2562449:E4Z61_RS13110 ^@ http://purl.uniprot.org/uniprot/A0A4P7J2X4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/2562449:E4Z61_RS11230 ^@ http://purl.uniprot.org/uniprot/A0A4P7J708 ^@ Similarity ^@ Belongs to the Hha/YmoA/Cnu family. http://togogenome.org/gene/2562449:E4Z61_RS00530 ^@ http://purl.uniprot.org/uniprot/A0A4P7IXT3 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family.|||In the N-terminal section; belongs to the transposase 2 family. http://togogenome.org/gene/2562449:E4Z61_RS12700 ^@ http://purl.uniprot.org/uniprot/A0A4P7J2R9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/2562449:E4Z61_RS17185 ^@ http://purl.uniprot.org/uniprot/A0A4P7J694 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.|||Belongs to the small heat shock protein (HSP20) family.|||Cytoplasm|||Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations. http://togogenome.org/gene/2562449:E4Z61_RS19400 ^@ http://purl.uniprot.org/uniprot/A0A4P7JA73 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/2562449:E4Z61_RS08080 ^@ http://purl.uniprot.org/uniprot/A0A4P7J0L7 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/2562449:E4Z61_RS11245 ^@ http://purl.uniprot.org/uniprot/A0A4P7J201 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/2562449:E4Z61_RS19695 ^@ http://purl.uniprot.org/uniprot/A0A4P7J7H6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/2562449:E4Z61_RS17905 ^@ http://purl.uniprot.org/uniprot/A0A4P7J9G3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/2562449:E4Z61_RS19025 ^@ http://purl.uniprot.org/uniprot/A0A4V1BQ85 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/2562449:E4Z61_RS12425 ^@ http://purl.uniprot.org/uniprot/A0A4P7J6X8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliQ/MopD/SpaQ family.|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS08140 ^@ http://purl.uniprot.org/uniprot/A0A4P7J4Z2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis.|||Role in flagellar biosynthesis. http://togogenome.org/gene/2562449:E4Z61_RS13465 ^@ http://purl.uniprot.org/uniprot/A0A4P7J4G5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/2562449:E4Z61_RS21090 ^@ http://purl.uniprot.org/uniprot/A0A4P7JCA8 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/2562449:E4Z61_RS00215 ^@ http://purl.uniprot.org/uniprot/A0A4P7IY98 ^@ Similarity ^@ Belongs to the aminoglycoside phosphotransferase family. http://togogenome.org/gene/2562449:E4Z61_RS12660 ^@ http://purl.uniprot.org/uniprot/A0A4P7J713 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/2562449:E4Z61_RS15780 ^@ http://purl.uniprot.org/uniprot/A0A4P7J463 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NusG family.|||Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.|||Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination. http://togogenome.org/gene/2562449:E4Z61_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1W2 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily.|||Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. http://togogenome.org/gene/2562449:E4Z61_RS18585 ^@ http://purl.uniprot.org/uniprot/A0A4P7J9T4 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/2562449:E4Z61_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A4P7IY75 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/2562449:E4Z61_RS08075 ^@ http://purl.uniprot.org/uniprot/A0A4P7J0P0 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/2562449:E4Z61_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1M4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/2562449:E4Z61_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A4P7IXM4 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/2562449:E4Z61_RS16995 ^@ http://purl.uniprot.org/uniprot/A0A4P7J4Q2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/2562449:E4Z61_RS00365 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1C8 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/2562449:E4Z61_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A4P7IZZ1 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/2562449:E4Z61_RS21870 ^@ http://purl.uniprot.org/uniprot/A0A4V1BQI4 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/2562449:E4Z61_RS16840 ^@ http://purl.uniprot.org/uniprot/A0A4P7J4M3 ^@ Similarity ^@ Belongs to the UPF0438 family. http://togogenome.org/gene/2562449:E4Z61_RS09375 ^@ http://purl.uniprot.org/uniprot/A0A4P7J438 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/2562449:E4Z61_RS23550 ^@ http://purl.uniprot.org/uniprot/A0A4P7J7U6 ^@ Function|||Subcellular Location Annotation ^@ Bacterial microcompartment|||The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low. http://togogenome.org/gene/2562449:E4Z61_RS02785 ^@ http://purl.uniprot.org/uniprot/A0A4P7IYE7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the bacterial microcompartments protein family.|||The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low. http://togogenome.org/gene/2562449:E4Z61_RS20810 ^@ http://purl.uniprot.org/uniprot/A0A4P7J9P3 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/2562449:E4Z61_RS18290 ^@ http://purl.uniprot.org/uniprot/A0A4V1BQ71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sulfur carrier protein TusA family.|||Cytoplasm|||Interacts with IscS.|||Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. http://togogenome.org/gene/2562449:E4Z61_RS19660 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5X3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS18965 ^@ http://purl.uniprot.org/uniprot/A0A4P7J6D9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/2562449:E4Z61_RS18165 ^@ http://purl.uniprot.org/uniprot/A0A4P7J9K8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm|||Required for resistance to DNA-damaging agents. http://togogenome.org/gene/2562449:E4Z61_RS18950 ^@ http://purl.uniprot.org/uniprot/A0A4P7J9Z8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/2562449:E4Z61_RS19045 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5V6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/2562449:E4Z61_RS18990 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5U4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/2562449:E4Z61_RS11360 ^@ http://purl.uniprot.org/uniprot/A0A4P7J265 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/2562449:E4Z61_RS13655 ^@ http://purl.uniprot.org/uniprot/A0A4P7J605 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer.|||The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. http://togogenome.org/gene/2562449:E4Z61_RS00370 ^@ http://purl.uniprot.org/uniprot/A0A4P7IXT1 ^@ Similarity ^@ Belongs to the peptidase S24 family. http://togogenome.org/gene/2562449:E4Z61_RS01320 ^@ http://purl.uniprot.org/uniprot/A0A4P7IYQ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2562449:E4Z61_RS06035 ^@ http://purl.uniprot.org/uniprot/A0A4P7IZT8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2562449:E4Z61_RS19345 ^@ http://purl.uniprot.org/uniprot/A0A4P7J611 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AaeX family.|||Cell membrane http://togogenome.org/gene/2562449:E4Z61_RS21425 ^@ http://purl.uniprot.org/uniprot/A0A4P7JCG4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2562449:E4Z61_RS11500 ^@ http://purl.uniprot.org/uniprot/A0A4V1BPU6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers. http://togogenome.org/gene/2562449:E4Z61_RS20985 ^@ http://purl.uniprot.org/uniprot/A0A4V1BQC1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LysR transcriptional regulatory family.|||Controls the transcription of genes involved in arginine and lysine metabolism.|||Homodimer. http://togogenome.org/gene/2562449:E4Z61_RS01770 ^@ http://purl.uniprot.org/uniprot/A0A4P7IY60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/2562449:E4Z61_RS13165 ^@ http://purl.uniprot.org/uniprot/A0A4P7J313 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Membrane|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/2562449:E4Z61_RS18970 ^@ http://purl.uniprot.org/uniprot/A0A4P7JB33 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/2562449:E4Z61_RS02430 ^@ http://purl.uniprot.org/uniprot/A0A4P7IZD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/2562449:E4Z61_RS16770 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5C1 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/2562449:E4Z61_RS12580 ^@ http://purl.uniprot.org/uniprot/A0A4V1BPW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RcsF family.|||Cell outer membrane|||Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects. http://togogenome.org/gene/2562449:E4Z61_RS19570 ^@ http://purl.uniprot.org/uniprot/A0A4P7JBF0 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/2562449:E4Z61_RS22195 ^@ http://purl.uniprot.org/uniprot/A0A4P7J718 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/2562449:E4Z61_RS00075 ^@ http://purl.uniprot.org/uniprot/A0A4P7IXI8 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/2562449:E4Z61_RS14535 ^@ http://purl.uniprot.org/uniprot/A0A4P7J6F4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/2562449:E4Z61_RS08295 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1Y7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/2562449:E4Z61_RS00460 ^@ http://purl.uniprot.org/uniprot/A0A4V1BP91 ^@ Similarity ^@ Belongs to the antirestriction protein family. http://togogenome.org/gene/2562449:E4Z61_RS18565 ^@ http://purl.uniprot.org/uniprot/A0A4P7J6Y9 ^@ Function|||Similarity ^@ Belongs to the FeoC family.|||May function as a transcriptional regulator that controls feoABC expression. http://togogenome.org/gene/2562449:E4Z61_RS21430 ^@ http://purl.uniprot.org/uniprot/A0A4V1BQC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS23185 ^@ http://purl.uniprot.org/uniprot/A0A4P7J7Q1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 2 iron ions per dimer. The dimer may bind additional iron ions.|||Homodimer; may form tetramers and higher multimers.|||Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. http://togogenome.org/gene/2562449:E4Z61_RS00175 ^@ http://purl.uniprot.org/uniprot/A0A4P7IXI0 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/2562449:E4Z61_RS23210 ^@ http://purl.uniprot.org/uniprot/A0A4P7JD99 ^@ Function|||Similarity ^@ Belongs to the IscX family.|||May function as iron donor in the assembly of iron-sulfur clusters. http://togogenome.org/gene/2562449:E4Z61_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A4P7J0U0 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS14815 ^@ http://purl.uniprot.org/uniprot/A0A4P7J922 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/2562449:E4Z61_RS11175 ^@ http://purl.uniprot.org/uniprot/A0A4P7J6Z8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/2562449:E4Z61_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1T8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2562449:E4Z61_RS19240 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5Z3 ^@ Function|||Similarity|||Subunit ^@ Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.|||Belongs to the transcriptional regulatory Fis family.|||Homodimer. http://togogenome.org/gene/2562449:E4Z61_RS13825 ^@ http://purl.uniprot.org/uniprot/A0A4P7J392 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/2562449:E4Z61_RS15885 ^@ http://purl.uniprot.org/uniprot/A0A4P7J496 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. http://togogenome.org/gene/2562449:E4Z61_RS00510 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1E3 ^@ Function|||Subunit ^@ Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.|||Homodimer. http://togogenome.org/gene/2562449:E4Z61_RS15765 ^@ http://purl.uniprot.org/uniprot/A0A4P7J9H8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.|||Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA. http://togogenome.org/gene/2562449:E4Z61_RS22085 ^@ http://purl.uniprot.org/uniprot/A0A4P7JBD1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/2562449:E4Z61_RS19965 ^@ http://purl.uniprot.org/uniprot/A0A4V1BQA2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine to yield pyruvate via analogous enamine/imine intermediates.|||In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers). http://togogenome.org/gene/2562449:E4Z61_RS16045 ^@ http://purl.uniprot.org/uniprot/A0A4P7J4C2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/2562449:E4Z61_RS18900 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5I9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/2562449:E4Z61_RS09220 ^@ http://purl.uniprot.org/uniprot/A0A4V1BPQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/2562449:E4Z61_RS17655 ^@ http://purl.uniprot.org/uniprot/A0A4P7J508 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/2562449:E4Z61_RS23055 ^@ http://purl.uniprot.org/uniprot/A0A4V1BQF8 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/2562449:E4Z61_RS15760 ^@ http://purl.uniprot.org/uniprot/A0A4P7J4Y7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/2562449:E4Z61_RS18325 ^@ http://purl.uniprot.org/uniprot/A0A4P7J8A6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/2562449:E4Z61_RS04075 ^@ http://purl.uniprot.org/uniprot/A0A4P7J362 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.|||Belongs to the Lpp family.|||Cell outer membrane|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||cell wall http://togogenome.org/gene/2562449:E4Z61_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1F3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2562449:E4Z61_RS10420 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1I6 ^@ Similarity ^@ Belongs to the UPF0250 family. http://togogenome.org/gene/2562449:E4Z61_RS04565 ^@ http://purl.uniprot.org/uniprot/A0A4P7IZ88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/2562449:E4Z61_RS19055 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5M1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/2562449:E4Z61_RS17010 ^@ http://purl.uniprot.org/uniprot/A0A4P7JA45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/2562449:E4Z61_RS23205 ^@ http://purl.uniprot.org/uniprot/A0A4P7J8A0 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/2562449:E4Z61_RS19050 ^@ http://purl.uniprot.org/uniprot/A0A4P7JA18 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/2562449:E4Z61_RS01760 ^@ http://purl.uniprot.org/uniprot/A0A4P7IY65 ^@ Similarity ^@ Belongs to the UPF0352 family. http://togogenome.org/gene/2562449:E4Z61_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A4P7J0G7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2562449:E4Z61_RS10555 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1N9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/2562449:E4Z61_RS02250 ^@ http://purl.uniprot.org/uniprot/A0A4P7IY77 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2562449:E4Z61_RS17545 ^@ http://purl.uniprot.org/uniprot/A0A4P7J9A3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/2562449:E4Z61_RS12825 ^@ http://purl.uniprot.org/uniprot/A0A4P7J3J4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. http://togogenome.org/gene/2562449:E4Z61_RS03860 ^@ http://purl.uniprot.org/uniprot/A0A4P7J326 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/2562449:E4Z61_RS23480 ^@ http://purl.uniprot.org/uniprot/A0A4P7JDE4 ^@ Function|||Subcellular Location Annotation ^@ Bacterial microcompartment|||The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low. http://togogenome.org/gene/2562449:E4Z61_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A4P7IZ31 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/2562449:E4Z61_RS12960 ^@ http://purl.uniprot.org/uniprot/A0A4P7J2W7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm|||Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine. http://togogenome.org/gene/2562449:E4Z61_RS10450 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1L9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2562449:E4Z61_RS14855 ^@ http://purl.uniprot.org/uniprot/A0A4P7J3R6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/2562449:E4Z61_RS19010 ^@ http://purl.uniprot.org/uniprot/A0A4P7J8U3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/2562449:E4Z61_RS06790 ^@ http://purl.uniprot.org/uniprot/A0A4V1BPK9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/2562449:E4Z61_RS19060 ^@ http://purl.uniprot.org/uniprot/A0A4P7J8V5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/2562449:E4Z61_RS19550 ^@ http://purl.uniprot.org/uniprot/A0A4P7JAA1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD). http://togogenome.org/gene/2562449:E4Z61_RS22040 ^@ http://purl.uniprot.org/uniprot/A0A4P7J8I5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/2562449:E4Z61_RS23195 ^@ http://purl.uniprot.org/uniprot/A0A4P7J7H1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HscB family.|||Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.|||Interacts with HscA and stimulates its ATPase activity. Interacts with IscU. http://togogenome.org/gene/2562449:E4Z61_RS12770 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5K4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 1 iron-sulfur cluster per subunit.|||Homodimer.|||Required for insertion of 4Fe-4S clusters for at least IspG. http://togogenome.org/gene/2562449:E4Z61_RS18975 ^@ http://purl.uniprot.org/uniprot/A0A4V1BQ84 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2562449:E4Z61_RS22775 ^@ http://purl.uniprot.org/uniprot/A0A4P7J7B4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/2562449:E4Z61_RS18870 ^@ http://purl.uniprot.org/uniprot/A0A4V1BQ82 ^@ Similarity ^@ Belongs to the SlyX family. http://togogenome.org/gene/2562449:E4Z61_RS16980 ^@ http://purl.uniprot.org/uniprot/A0A4P7J4R9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS01265 ^@ http://purl.uniprot.org/uniprot/A0A4P7IYP5 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/2562449:E4Z61_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A4P7IYU6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/2562449:E4Z61_RS11520 ^@ http://purl.uniprot.org/uniprot/A0A4P7J292 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.|||Cell outer membrane http://togogenome.org/gene/2562449:E4Z61_RS17480 ^@ http://purl.uniprot.org/uniprot/A0A4P7J504 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2562449:E4Z61_RS19020 ^@ http://purl.uniprot.org/uniprot/A0A4P7JB43 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/2562449:E4Z61_RS21715 ^@ http://purl.uniprot.org/uniprot/A0A4P7JB80 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsB family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/2562449:E4Z61_RS19590 ^@ http://purl.uniprot.org/uniprot/A0A4P7J626 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/2562449:E4Z61_RS23655 ^@ http://purl.uniprot.org/uniprot/A0A4P7J7Q6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2562449:E4Z61_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A4P7IYP8 ^@ Similarity ^@ Belongs to the UPF0227 family. http://togogenome.org/gene/2562449:E4Z61_RS03250 ^@ http://purl.uniprot.org/uniprot/A0A4P7IYL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2562449:E4Z61_RS16475 ^@ http://purl.uniprot.org/uniprot/A0A4P7J4I3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TrkH potassium transport family.|||Cell inner membrane|||Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS01590 ^@ http://purl.uniprot.org/uniprot/A0A4P7IY48 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the RcsB family.|||Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.|||Interacts with RcsD.|||Phosphorylated and activated by RcsD. http://togogenome.org/gene/2562449:E4Z61_RS05500 ^@ http://purl.uniprot.org/uniprot/A0A4V1BPI6 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/2562449:E4Z61_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A4P7IZI7 ^@ Similarity ^@ Belongs to the UPF0265 family. http://togogenome.org/gene/2562449:E4Z61_RS03835 ^@ http://purl.uniprot.org/uniprot/A0A4P7J2Z9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/2562449:E4Z61_RS00090 ^@ http://purl.uniprot.org/uniprot/A0A4P7IY83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS01350 ^@ http://purl.uniprot.org/uniprot/A0A4P7IY08 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/2562449:E4Z61_RS17110 ^@ http://purl.uniprot.org/uniprot/A0A4P7J7P4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/2562449:E4Z61_RS20055 ^@ http://purl.uniprot.org/uniprot/A0A4P7J6Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS13105 ^@ http://purl.uniprot.org/uniprot/A0A4P7J4A6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/2562449:E4Z61_RS00095 ^@ http://purl.uniprot.org/uniprot/A0A4P7J186 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/2562449:E4Z61_RS19785 ^@ http://purl.uniprot.org/uniprot/A0A4P7J984 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SIS family. DiaA subfamily.|||Homotetramer; dimer of dimers.|||Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. http://togogenome.org/gene/2562449:E4Z61_RS19625 ^@ http://purl.uniprot.org/uniprot/A0A4P7JBF8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/2562449:E4Z61_RS00255 ^@ http://purl.uniprot.org/uniprot/A0A4P7IXK0 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/2562449:E4Z61_RS15595 ^@ http://purl.uniprot.org/uniprot/A0A4V1BQ22 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S51 family.|||Cytoplasm|||Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids. http://togogenome.org/gene/2562449:E4Z61_RS15425 ^@ http://purl.uniprot.org/uniprot/A0A4P7J6T5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/2562449:E4Z61_RS22890 ^@ http://purl.uniprot.org/uniprot/A0A4P7J849 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/2562449:E4Z61_RS00235 ^@ http://purl.uniprot.org/uniprot/A0A4P7IXI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS19070 ^@ http://purl.uniprot.org/uniprot/A0A4P7JB57 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/2562449:E4Z61_RS22975 ^@ http://purl.uniprot.org/uniprot/A0A4P7J7L6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/2562449:E4Z61_RS19515 ^@ http://purl.uniprot.org/uniprot/A0A4P7J6P5 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/2562449:E4Z61_RS00280 ^@ http://purl.uniprot.org/uniprot/A0A4P7IYI3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/2562449:E4Z61_RS19030 ^@ http://purl.uniprot.org/uniprot/A0A4P7J765 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2562449:E4Z61_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1D4 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/2562449:E4Z61_RS18960 ^@ http://purl.uniprot.org/uniprot/A0A4P7J8T3 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/2562449:E4Z61_RS19495 ^@ http://purl.uniprot.org/uniprot/A0A4P7J637 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RapZ-like family. RapZ subfamily.|||Homotrimer.|||Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS. http://togogenome.org/gene/2562449:E4Z61_RS18945 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5U0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2562449:E4Z61_RS14070 ^@ http://purl.uniprot.org/uniprot/A0A4P7J867 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2562449:E4Z61_RS08270 ^@ http://purl.uniprot.org/uniprot/A0A4P7J0K2 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/2562449:E4Z61_RS18980 ^@ http://purl.uniprot.org/uniprot/A0A4P7J756 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/2562449:E4Z61_RS19040 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5V2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/2562449:E4Z61_RS23400 ^@ http://purl.uniprot.org/uniprot/A0A4P7JBY8 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/2562449:E4Z61_RS16060 ^@ http://purl.uniprot.org/uniprot/A0A4P7J762 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraA family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.|||Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB. http://togogenome.org/gene/2562449:E4Z61_RS08540 ^@ http://purl.uniprot.org/uniprot/A0A4P7J3R4 ^@ Function ^@ May be involved in the biogenesis of curli organelles. http://togogenome.org/gene/2562449:E4Z61_RS09215 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5Z1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/2562449:E4Z61_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A4P7IZ77 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2562449:E4Z61_RS03525 ^@ http://purl.uniprot.org/uniprot/A0A4P7IYQ4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0756 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2562449:E4Z61_RS18995 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5U8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2562449:E4Z61_RS19120 ^@ http://purl.uniprot.org/uniprot/A0A4P7JB67 ^@ Similarity ^@ Belongs to the Smg family. http://togogenome.org/gene/2562449:E4Z61_RS23180 ^@ http://purl.uniprot.org/uniprot/A0A4P7J7M9 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/2562449:E4Z61_RS20360 ^@ http://purl.uniprot.org/uniprot/A0A4P7J7S2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/2562449:E4Z61_RS01690 ^@ http://purl.uniprot.org/uniprot/A0A4V1BPB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/2562449:E4Z61_RS18670 ^@ http://purl.uniprot.org/uniprot/A0A4V1BQ78 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2562449:E4Z61_RS09210 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1V5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/2562449:E4Z61_RS17105 ^@ http://purl.uniprot.org/uniprot/A0A4P7J4S0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/2562449:E4Z61_RS00265 ^@ http://purl.uniprot.org/uniprot/A0A4P7IXM4 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/2562449:E4Z61_RS03290 ^@ http://purl.uniprot.org/uniprot/A0A4P7IYR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HflD family.|||Cell membrane|||Cytoplasm http://togogenome.org/gene/2562449:E4Z61_RS11365 ^@ http://purl.uniprot.org/uniprot/A0A4P7J6E8 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/2562449:E4Z61_RS01885 ^@ http://purl.uniprot.org/uniprot/A0A4P7J0S1 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/2562449:E4Z61_RS15775 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5M7 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/2562449:E4Z61_RS14780 ^@ http://purl.uniprot.org/uniprot/A0A4P7J3R3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FrdC family.|||Cell membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. http://togogenome.org/gene/2562449:E4Z61_RS18985 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5K5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2562449:E4Z61_RS07205 ^@ http://purl.uniprot.org/uniprot/A0A4P7J0W7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS17270 ^@ http://purl.uniprot.org/uniprot/A0A4P7J957 ^@ Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Dimer of large and small chains. http://togogenome.org/gene/2562449:E4Z61_RS17540 ^@ http://purl.uniprot.org/uniprot/A0A4P7J513 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/2562449:E4Z61_RS20470 ^@ http://purl.uniprot.org/uniprot/A0A4P7J6G5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediates zinc uptake. May also transport other divalent cations.|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS19405 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5S6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/2562449:E4Z61_RS17115 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5H4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/2562449:E4Z61_RS07705 ^@ http://purl.uniprot.org/uniprot/A0A4P7J4Q9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/2562449:E4Z61_RS00270 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1A9 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/2562449:E4Z61_RS08350 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1Z4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/2562449:E4Z61_RS18935 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5J6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2562449:E4Z61_RS01285 ^@ http://purl.uniprot.org/uniprot/A0A4P7IY10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0208 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS17125 ^@ http://purl.uniprot.org/uniprot/A0A4V1BQ49 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/2562449:E4Z61_RS11545 ^@ http://purl.uniprot.org/uniprot/A0A4P7J7D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A4P7J4T3 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/2562449:E4Z61_RS09890 ^@ http://purl.uniprot.org/uniprot/A0A4P7J2T1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/2562449:E4Z61_RS01960 ^@ http://purl.uniprot.org/uniprot/A0A4P7IY92 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/2562449:E4Z61_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A4P7J1L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS14365 ^@ http://purl.uniprot.org/uniprot/A0A4P7J3I7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/2562449:E4Z61_RS00180 ^@ http://purl.uniprot.org/uniprot/A0A4P7IXP7 ^@ Similarity ^@ Belongs to the aminoglycoside phosphotransferase family. http://togogenome.org/gene/2562449:E4Z61_RS15685 ^@ http://purl.uniprot.org/uniprot/A0A4P7J468 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/2562449:E4Z61_RS09915 ^@ http://purl.uniprot.org/uniprot/A0A4P7J195 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/2562449:E4Z61_RS18550 ^@ http://purl.uniprot.org/uniprot/A0A4P7J664 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NfuA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.|||Homodimer.|||Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. http://togogenome.org/gene/2562449:E4Z61_RS14195 ^@ http://purl.uniprot.org/uniprot/A0A4P7J3J3 ^@ Similarity|||Subunit ^@ Belongs to the RutC family.|||Homotrimer. http://togogenome.org/gene/2562449:E4Z61_RS23170 ^@ http://purl.uniprot.org/uniprot/A0A4P7J915 ^@ Cofactor|||Function ^@ Binds 1 [2Fe-2S] cluster.|||Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. http://togogenome.org/gene/2562449:E4Z61_RS18955 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5K3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/2562449:E4Z61_RS17670 ^@ http://purl.uniprot.org/uniprot/A0A4P7JAF0 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/2562449:E4Z61_RS17920 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5V8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2562449:E4Z61_RS01335 ^@ http://purl.uniprot.org/uniprot/A0A4P7IYY6 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/2562449:E4Z61_RS21750 ^@ http://purl.uniprot.org/uniprot/A0A4P7J6X2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoS subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. http://togogenome.org/gene/2562449:E4Z61_RS02090 ^@ http://purl.uniprot.org/uniprot/A0A4P7IY58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0387 family.|||Cell membrane http://togogenome.org/gene/2562449:E4Z61_RS00185 ^@ http://purl.uniprot.org/uniprot/A0A4P7IXM4 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/2562449:E4Z61_RS11345 ^@ http://purl.uniprot.org/uniprot/A0A4P7J3F1 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/2562449:E4Z61_RS16985 ^@ http://purl.uniprot.org/uniprot/A0A4P7J4S5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/2562449:E4Z61_RS12570 ^@ http://purl.uniprot.org/uniprot/A0A4P7J3F0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2562449:E4Z61_RS01700 ^@ http://purl.uniprot.org/uniprot/A0A4P7IY61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmD/CycX/HelD family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/2562449:E4Z61_RS19000 ^@ http://purl.uniprot.org/uniprot/A0A4P7JA09 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/2562449:E4Z61_RS13440 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5W7 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/2562449:E4Z61_RS13645 ^@ http://purl.uniprot.org/uniprot/A0A4P7J7J0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/2562449:E4Z61_RS14820 ^@ http://purl.uniprot.org/uniprot/A0A4V1BQ08 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/2562449:E4Z61_RS14530 ^@ http://purl.uniprot.org/uniprot/A0A4P7J3L5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/2562449:E4Z61_RS00275 ^@ http://purl.uniprot.org/uniprot/A0A4V1BP88 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Cell inner membrane|||Membrane|||Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. http://togogenome.org/gene/2562449:E4Z61_RS17485 ^@ http://purl.uniprot.org/uniprot/A0A4P7J994 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/2562449:E4Z61_RS19005 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5L2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/2562449:E4Z61_RS20760 ^@ http://purl.uniprot.org/uniprot/A0A4P7J785 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.|||Monomer. http://togogenome.org/gene/2562449:E4Z61_RS19305 ^@ http://purl.uniprot.org/uniprot/A0A4P7J5Q9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/2562449:E4Z61_RS21695 ^@ http://purl.uniprot.org/uniprot/A0A4P7J8D2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/2562449:E4Z61_RS16015 ^@ http://purl.uniprot.org/uniprot/A0A4P7J529 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MetJ family.|||Cytoplasm|||Does not bind DNA by a helix-turn-helix motif.|||Homodimer.|||This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.