http://togogenome.org/gene/2745503:HU724_RS04710 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBV4 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/2745503:HU724_RS09195 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDM3 ^@ Function|||Similarity|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ. http://togogenome.org/gene/2745503:HU724_RS18710 ^@ http://purl.uniprot.org/uniprot/A0A9E6P727 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS00095 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL19 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS24780 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8S9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. MrdA subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall.|||Cell inner membrane http://togogenome.org/gene/2745503:HU724_RS05095 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/2745503:HU724_RS06915 ^@ http://purl.uniprot.org/uniprot/A0A9E6PC27 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS23255 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKW7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS21285 ^@ http://purl.uniprot.org/uniprot/A0A9E6P892 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FlgA family.|||Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS00995 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNF4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/2745503:HU724_RS09635 ^@ http://purl.uniprot.org/uniprot/A0A9E6TP73 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS04020 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/2745503:HU724_RS15135 ^@ http://purl.uniprot.org/uniprot/A0A9E6TK29 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/2745503:HU724_RS00585 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMJ5 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/2745503:HU724_RS20115 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8C1 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/2745503:HU724_RS25390 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/2745503:HU724_RS26960 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9I9 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/2745503:HU724_RS09295 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMN1 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/2745503:HU724_RS07525 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCC7 ^@ Function ^@ Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions. http://togogenome.org/gene/2745503:HU724_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBJ8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS07495 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMB9 ^@ Function|||Similarity ^@ An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.|||Belongs to the SdhE FAD assembly factor family. http://togogenome.org/gene/2745503:HU724_RS05320 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNE0 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/2745503:HU724_RS20375 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS01770 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell outer membrane http://togogenome.org/gene/2745503:HU724_RS23980 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9U4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2745503:HU724_RS23670 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9E0 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/2745503:HU724_RS21885 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8V8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS04655 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell inner membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/2745503:HU724_RS06680 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN61 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/2745503:HU724_RS00055 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAR6 ^@ Function|||Similarity ^@ Belongs to the DadA oxidoreductase family.|||Oxidative deamination of D-amino acids. http://togogenome.org/gene/2745503:HU724_RS20530 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7L4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS15335 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS21170 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8M0 ^@ Similarity ^@ Belongs to the WrbA family. http://togogenome.org/gene/2745503:HU724_RS24920 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8V4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/2745503:HU724_RS08350 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMH6 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/2745503:HU724_RS24475 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBA1 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/2745503:HU724_RS05075 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMS7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RlpA family.|||Cell membrane|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/2745503:HU724_RS22605 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8C6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS01320 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAF6 ^@ Function|||Similarity ^@ Belongs to the catalase family. HPII subfamily.|||Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.|||Serves to protect cells from the toxic effects of hydrogen peroxide. http://togogenome.org/gene/2745503:HU724_RS25135 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9Y1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS20585 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7N4 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/2745503:HU724_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBD1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/2745503:HU724_RS26800 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAC4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS08985 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS09240 ^@ http://purl.uniprot.org/uniprot/A0A9E6PE37 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/2745503:HU724_RS09055 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNI3 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/2745503:HU724_RS22610 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL67 ^@ Activity Regulation|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/2745503:HU724_RS16570 ^@ http://purl.uniprot.org/uniprot/A0A9E6P625 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/2745503:HU724_RS14615 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5B0 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS22585 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS18440 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6Y3 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/2745503:HU724_RS04330 ^@ http://purl.uniprot.org/uniprot/A0A9E6PC68 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/2745503:HU724_RS02850 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBT7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/2745503:HU724_RS25760 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKQ2 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/2745503:HU724_RS22975 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8K3 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/2745503:HU724_RS14250 ^@ http://purl.uniprot.org/uniprot/A0A9E6P580 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS07065 ^@ http://purl.uniprot.org/uniprot/A0A9E6PC49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS05135 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD41 ^@ Similarity ^@ Belongs to the UPF0307 family. http://togogenome.org/gene/2745503:HU724_RS24350 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9L6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/2745503:HU724_RS00385 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA50 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/2745503:HU724_RS11605 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEG6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2745503:HU724_RS25380 ^@ http://purl.uniprot.org/uniprot/A0A9E6P913 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2745503:HU724_RS22370 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7X0 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/2745503:HU724_RS09790 ^@ http://purl.uniprot.org/uniprot/A0A9E6TP79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/2745503:HU724_RS08430 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN22 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/2745503:HU724_RS00225 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Cell membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/2745503:HU724_RS26335 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA63 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/2745503:HU724_RS20810 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7J9 ^@ Function|||Similarity ^@ Belongs to the DUF177 domain family.|||Plays a role in synthesis, processing and/or stability of 23S rRNA. http://togogenome.org/gene/2745503:HU724_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/2745503:HU724_RS21695 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8E0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/2745503:HU724_RS22635 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS24970 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/2745503:HU724_RS05755 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS09460 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNM8 ^@ Similarity ^@ Belongs to the peptidase S24 family. http://togogenome.org/gene/2745503:HU724_RS05290 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/2745503:HU724_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA18 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family. http://togogenome.org/gene/2745503:HU724_RS21935 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8T2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS18055 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6U6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2745503:HU724_RS23320 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9L1 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/2745503:HU724_RS14870 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5G3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS19380 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7V8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS22000 ^@ http://purl.uniprot.org/uniprot/A0A9E6TK20 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/2745503:HU724_RS18480 ^@ http://purl.uniprot.org/uniprot/A0A9E6P704 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS08080 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS17590 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6C2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NRAMP family.|||Cell membrane|||H(+)-stimulated, divalent metal cation uptake system. http://togogenome.org/gene/2745503:HU724_RS12075 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDY4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/2745503:HU724_RS06020 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCR5 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS24785 ^@ http://purl.uniprot.org/uniprot/A0A9E6P932 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/2745503:HU724_RS21025 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS21905 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKN9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/2745503:HU724_RS25400 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKN8 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/2745503:HU724_RS02690 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBH7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS05990 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMM7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/2745503:HU724_RS25340 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9W3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2745503:HU724_RS22270 ^@ http://purl.uniprot.org/uniprot/A0A9E6P939 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBR7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/2745503:HU724_RS04995 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMS2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/2745503:HU724_RS05485 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCG9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS08635 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic sulfate-binding protein family.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS03710 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBY7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS23975 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8I0 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/2745503:HU724_RS06000 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCY3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/2745503:HU724_RS05215 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBV8 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/2745503:HU724_RS07785 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCV6 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/2745503:HU724_RS03315 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS25060 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9W7 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/2745503:HU724_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCV0 ^@ Similarity|||Subunit ^@ Belongs to the MoaE family.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/2745503:HU724_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS18010 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJY6 ^@ Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudJ subfamily.|||Monomer. http://togogenome.org/gene/2745503:HU724_RS22135 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7T7 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/2745503:HU724_RS10725 ^@ http://purl.uniprot.org/uniprot/A0A9E6PE83 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/2745503:HU724_RS19445 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/2745503:HU724_RS20765 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKW0 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/2745503:HU724_RS06015 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBU9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbC subfamily.|||Periplasm|||Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. http://togogenome.org/gene/2745503:HU724_RS19860 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL07 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.|||Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.|||Cytoplasm|||Probably phosphorylates lipids; the in vivo substrate is unknown. http://togogenome.org/gene/2745503:HU724_RS11565 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNY8 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/2745503:HU724_RS02670 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMX6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the calycin superfamily. Lipocalin family.|||Cell outer membrane|||Homodimer.|||Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids. http://togogenome.org/gene/2745503:HU724_RS07890 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMZ0 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/2745503:HU724_RS10210 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDW4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS22245 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLF8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS18245 ^@ http://purl.uniprot.org/uniprot/A0A9E6TK60 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/2745503:HU724_RS17985 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6D9 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/2745503:HU724_RS17980 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6T7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/2745503:HU724_RS07015 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN53 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/2745503:HU724_RS26140 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS18125 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7N5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS05880 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBR0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase Slt family.|||Cell outer membrane|||In the C-terminal section; belongs to the transglycosylase Slt family.|||In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.|||The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain. http://togogenome.org/gene/2745503:HU724_RS09685 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDQ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ribosome modulation factor family.|||Cytoplasm|||During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes). http://togogenome.org/gene/2745503:HU724_RS25860 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA24 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBZ2 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/2745503:HU724_RS27200 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS01020 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAM5 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/2745503:HU724_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBC6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS08375 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS04750 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLT5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS11420 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLR2 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/2745503:HU724_RS21585 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7M6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS18005 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKC0 ^@ Cofactor|||Similarity ^@ Belongs to the monomeric-type IDH family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/2745503:HU724_RS07515 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDH2 ^@ Similarity ^@ Belongs to the RseA family. http://togogenome.org/gene/2745503:HU724_RS09200 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDJ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/2745503:HU724_RS14375 ^@ http://purl.uniprot.org/uniprot/A0A9E6P633 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS05855 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS08255 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDB6 ^@ Function|||Similarity ^@ Belongs to the rhamnosyl O-methyltransferase family.|||Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD). http://togogenome.org/gene/2745503:HU724_RS00575 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL49 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. http://togogenome.org/gene/2745503:HU724_RS18095 ^@ http://purl.uniprot.org/uniprot/A0A9E6TK50 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2745503:HU724_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBP7 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS23360 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8Z0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/2745503:HU724_RS23420 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZapG family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS27405 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL12 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/2745503:HU724_RS25205 ^@ http://purl.uniprot.org/uniprot/A0A9E6P916 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/2745503:HU724_RS21925 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8F3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2745503:HU724_RS25560 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA33 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS09535 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNN2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A9E6TME6 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS26640 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAF9 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. RsmD family.|||Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle. http://togogenome.org/gene/2745503:HU724_RS26950 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAJ4 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/2745503:HU724_RS20525 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7B3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/2745503:HU724_RS01340 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL81 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/2745503:HU724_RS08950 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNH8 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/2745503:HU724_RS12025 ^@ http://purl.uniprot.org/uniprot/A0A9E6PF24 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/2745503:HU724_RS25370 ^@ http://purl.uniprot.org/uniprot/A0A9E6P914 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/2745503:HU724_RS09610 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class II aldolase/RraA-like family.|||Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.|||Homotrimer. http://togogenome.org/gene/2745503:HU724_RS21490 ^@ http://purl.uniprot.org/uniprot/A0A9E6P819 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/2745503:HU724_RS22500 ^@ http://purl.uniprot.org/uniprot/A0A9E6P846 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/2745503:HU724_RS26820 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9G1 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/2745503:HU724_RS05105 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCJ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Cell inner membrane|||Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.|||Membrane http://togogenome.org/gene/2745503:HU724_RS11255 ^@ http://purl.uniprot.org/uniprot/A0A9E6PES7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.|||Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.|||Homotetramer; dimer of dimers. http://togogenome.org/gene/2745503:HU724_RS22885 ^@ http://purl.uniprot.org/uniprot/A0A9E6P952 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/2745503:HU724_RS05045 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBI1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS21835 ^@ http://purl.uniprot.org/uniprot/A0A9E6TK08 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2745503:HU724_RS20780 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKL6 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/2745503:HU724_RS09010 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS05630 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS11995 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDX6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS15070 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6C8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2745503:HU724_RS00050 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9Q3 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/2745503:HU724_RS20360 ^@ http://purl.uniprot.org/uniprot/A0A9E6P760 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/2745503:HU724_RS05995 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNI9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/2745503:HU724_RS25530 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLA4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COQ7 family.|||Binds 2 iron ions per subunit.|||Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS24550 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLG6 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/2745503:HU724_RS03605 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMK6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.|||Cytoplasm|||Specifically methylates the ribose of guanosine 2251 in 23S rRNA. http://togogenome.org/gene/2745503:HU724_RS26675 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9P2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/2745503:HU724_RS18455 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6M8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/2745503:HU724_RS22340 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8Y2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS09905 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEL3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Binds 1 copper ion per subunit, denoted as copper B.|||Binds 2 heme groups per subunit, denoted as high- and low-spin.|||Membrane http://togogenome.org/gene/2745503:HU724_RS26290 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9J2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS18525 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6Q1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS25175 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN42 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b560 family.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/2745503:HU724_RS16815 ^@ http://purl.uniprot.org/uniprot/A0A9E6P620 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS21790 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7V9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS25350 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9U7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2745503:HU724_RS20590 ^@ http://purl.uniprot.org/uniprot/A0A9E6P786 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/2745503:HU724_RS18830 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7P8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS09680 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDU5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/2745503:HU724_RS16535 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6S5 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/2745503:HU724_RS20605 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7M2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS19510 ^@ http://purl.uniprot.org/uniprot/A0A9E6TK76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. Thiolase family.|||Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.|||Cytoplasm|||Heterotetramer of two alpha chains (FadB) and two beta chains (FadA). http://togogenome.org/gene/2745503:HU724_RS22915 ^@ http://purl.uniprot.org/uniprot/A0A9E6P837 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamB family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/2745503:HU724_RS26700 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKW2 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/2745503:HU724_RS13140 ^@ http://purl.uniprot.org/uniprot/A0A9E6TP24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS23005 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKV4 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/2745503:HU724_RS17960 ^@ http://purl.uniprot.org/uniprot/A0A9E6P777 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolA family.|||Monomer.|||Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).|||Periplasm http://togogenome.org/gene/2745503:HU724_RS03190 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB29 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/2745503:HU724_RS26585 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9Q5 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS24030 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9E2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS18825 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS24240 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLE8 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/2745503:HU724_RS10735 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDK8 ^@ Similarity ^@ Belongs to the EndA/NucM nuclease family. http://togogenome.org/gene/2745503:HU724_RS11990 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEM1 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/2745503:HU724_RS01560 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM81 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/2745503:HU724_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.|||Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS25190 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9U2 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/2745503:HU724_RS22025 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8U2 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/2745503:HU724_RS04685 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamE family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/2745503:HU724_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/2745503:HU724_RS06500 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCU3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoS subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. http://togogenome.org/gene/2745503:HU724_RS09380 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMN6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/2745503:HU724_RS17190 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKG0 ^@ Similarity ^@ Belongs to the dihydropyrimidine dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS20010 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL15 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/2745503:HU724_RS18110 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7D9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2745503:HU724_RS26495 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9E5 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/2745503:HU724_RS21985 ^@ http://purl.uniprot.org/uniprot/A0A9E6P848 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/2745503:HU724_RS23985 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8I1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. http://togogenome.org/gene/2745503:HU724_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAZ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/2745503:HU724_RS10180 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNQ0 ^@ Caution|||Function|||Similarity ^@ Belongs to the Dus family. DusC subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS27150 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS10845 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMX9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/2745503:HU724_RS05210 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD50 ^@ Function|||Similarity|||Subunit ^@ Belongs to the KdsC family.|||Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.|||Homotetramer. http://togogenome.org/gene/2745503:HU724_RS26395 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS00950 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/2745503:HU724_RS09810 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS18080 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/2745503:HU724_RS25255 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL92 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2745503:HU724_RS01215 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0391 family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS17460 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6B8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/2745503:HU724_RS00130 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAS9 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/2745503:HU724_RS15600 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell outer membrane http://togogenome.org/gene/2745503:HU724_RS05340 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBM5 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS22895 ^@ http://purl.uniprot.org/uniprot/A0A9E6P993 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS18905 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7P6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2745503:HU724_RS25230 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8Z1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/2745503:HU724_RS03545 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/2745503:HU724_RS25320 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLJ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/2745503:HU724_RS04340 ^@ http://purl.uniprot.org/uniprot/A0A9E6PC29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS05865 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/2745503:HU724_RS23075 ^@ http://purl.uniprot.org/uniprot/A0A9E6P857 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/2745503:HU724_RS24685 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8S2 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/2745503:HU724_RS01835 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL98 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS08405 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/2745503:HU724_RS16935 ^@ http://purl.uniprot.org/uniprot/A0A9E6TK47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS07480 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD01 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS21660 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7N3 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/2745503:HU724_RS08810 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN48 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/2745503:HU724_RS06150 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNK0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS22950 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8U0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/2745503:HU724_RS03130 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.|||Cell membrane|||K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels. http://togogenome.org/gene/2745503:HU724_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAD0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/2745503:HU724_RS13010 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS17990 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7G7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/2745503:HU724_RS17215 ^@ http://purl.uniprot.org/uniprot/A0A9E6P779 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell inner membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/2745503:HU724_RS02580 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM10 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/2745503:HU724_RS24790 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLI9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/2745503:HU724_RS19410 ^@ http://purl.uniprot.org/uniprot/A0A9E6P806 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/2745503:HU724_RS03685 ^@ http://purl.uniprot.org/uniprot/A0A9E6TML3 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/2745503:HU724_RS22920 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8E9 ^@ Similarity ^@ Belongs to the YfgM family. http://togogenome.org/gene/2745503:HU724_RS08775 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCU8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/2745503:HU724_RS20390 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJR7 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS04785 ^@ http://purl.uniprot.org/uniprot/A0A9E6PC75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/2745503:HU724_RS02765 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBI5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/2745503:HU724_RS19365 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKD0 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/2745503:HU724_RS27210 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAN9 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/2745503:HU724_RS25585 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9J4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/2745503:HU724_RS06770 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCN5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/2745503:HU724_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB06 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS25395 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLJ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/2745503:HU724_RS23300 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9B9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/2745503:HU724_RS01370 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS23225 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9K1 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/2745503:HU724_RS05850 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCW3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/2745503:HU724_RS17950 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKK7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/2745503:HU724_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A9E6TP03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS06355 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCA5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS09630 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN86 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2745503:HU724_RS18170 ^@ http://purl.uniprot.org/uniprot/A0A9E6TK55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS01505 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS17575 ^@ http://purl.uniprot.org/uniprot/A0A9E6P718 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2745503:HU724_RS21065 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8Q0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS25675 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GlpE family.|||Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS25705 ^@ http://purl.uniprot.org/uniprot/A0A9E6P972 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/2745503:HU724_RS14860 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5D1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS10805 ^@ http://purl.uniprot.org/uniprot/A0A9E6PE62 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2745503:HU724_RS18695 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7R2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS18050 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7M5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2745503:HU724_RS09120 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS27100 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLI3 ^@ Function|||Similarity|||Subunit ^@ Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.|||Belongs to the ZapA family. Type 1 subfamily.|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/2745503:HU724_RS21385 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8A4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/2745503:HU724_RS23580 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKY7 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/2745503:HU724_RS07025 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMT8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS07085 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS02295 ^@ http://purl.uniprot.org/uniprot/A0A9E6PF36 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol monophosphatase superfamily. CysQ family.|||Cell inner membrane|||Converts adenosine-3',5'-bisphosphate (PAP) to AMP. http://togogenome.org/gene/2745503:HU724_RS20400 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL37 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/2745503:HU724_RS07690 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD76 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/2745503:HU724_RS02175 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBB9 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/2745503:HU724_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAZ9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2745503:HU724_RS02800 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB92 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/2745503:HU724_RS01235 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBH9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS02430 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBL2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS22675 ^@ http://purl.uniprot.org/uniprot/A0A9E6P964 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LysR transcriptional regulatory family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS24305 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0114 family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS02710 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAN0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/2745503:HU724_RS21875 ^@ http://purl.uniprot.org/uniprot/A0A9E6P861 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS23020 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLN7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/2745503:HU724_RS20830 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8H8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/2745503:HU724_RS01210 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ivy family.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS23125 ^@ http://purl.uniprot.org/uniprot/A0A9E6P987 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS25360 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA11 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS06510 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBY5 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/2745503:HU724_RS26545 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLF0 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/2745503:HU724_RS23355 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLQ8 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Rieske iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||The Rieske protein is a high potential 2Fe-2S protein.|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/2745503:HU724_RS25450 ^@ http://purl.uniprot.org/uniprot/A0A9E6P945 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/2745503:HU724_RS04770 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCF0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/2745503:HU724_RS22925 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL82 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS05280 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBK1 ^@ Function ^@ Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions. http://togogenome.org/gene/2745503:HU724_RS08145 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS22930 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKU9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/2745503:HU724_RS13450 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNE5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/2745503:HU724_RS25685 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM42 ^@ Similarity ^@ Belongs to the UPF0229 family. http://togogenome.org/gene/2745503:HU724_RS22805 ^@ http://purl.uniprot.org/uniprot/A0A9E6P954 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.|||Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS03550 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBZ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/2745503:HU724_RS26725 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAB3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS05060 ^@ http://purl.uniprot.org/uniprot/A0A9E6PC05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS07855 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCE7 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/2745503:HU724_RS25840 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLL5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS26390 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/2745503:HU724_RS26340 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9D3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/2745503:HU724_RS16920 ^@ http://purl.uniprot.org/uniprot/A0A9E6P708 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS22960 ^@ http://purl.uniprot.org/uniprot/A0A9E6P966 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/2745503:HU724_RS19915 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAC1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/2745503:HU724_RS05250 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCI5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS10135 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDC2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/2745503:HU724_RS13455 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS22965 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8A7 ^@ Function|||Similarity ^@ Belongs to the heat shock protein 70 family.|||Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. http://togogenome.org/gene/2745503:HU724_RS09015 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS14920 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5E1 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/2745503:HU724_RS24455 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8N8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS08575 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMI8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/2745503:HU724_RS26980 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS03145 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN06 ^@ Function|||Similarity|||Subunit ^@ Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.|||Belongs to the ZapA family. Type 1 subfamily.|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/2745503:HU724_RS21260 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKY2 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/2745503:HU724_RS19975 ^@ http://purl.uniprot.org/uniprot/A0A9E6P873 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/2745503:HU724_RS23325 ^@ http://purl.uniprot.org/uniprot/A0A9E6P886 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/2745503:HU724_RS05255 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCL6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/2745503:HU724_RS08780 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell inner membrane|||Component of the transport system for branched-chain amino acids.|||Membrane http://togogenome.org/gene/2745503:HU724_RS27785 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7Y9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2745503:HU724_RS15915 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5S4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/2745503:HU724_RS00230 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/2745503:HU724_RS25265 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9V2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/2745503:HU724_RS12865 ^@ http://purl.uniprot.org/uniprot/A0A9E6TP84 ^@ Similarity ^@ Belongs to the MbcT/ParT/Res family. http://togogenome.org/gene/2745503:HU724_RS25720 ^@ http://purl.uniprot.org/uniprot/A0A9E6P951 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/2745503:HU724_RS16515 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJU9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS26155 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLD3 ^@ Function ^@ Repressor involved in choline regulation of the bet genes.|||Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine. http://togogenome.org/gene/2745503:HU724_RS03985 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCK8 ^@ Similarity ^@ Belongs to the transcriptional regulatory Fis family. http://togogenome.org/gene/2745503:HU724_RS09225 ^@ http://purl.uniprot.org/uniprot/A0A9E6TP42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS22445 ^@ http://purl.uniprot.org/uniprot/A0A9E6P927 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/2745503:HU724_RS20820 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7S0 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/2745503:HU724_RS06055 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMZ2 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/2745503:HU724_RS05835 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM11 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/2745503:HU724_RS00200 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAN4 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/2745503:HU724_RS25420 ^@ http://purl.uniprot.org/uniprot/A0A9E6P935 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/2745503:HU724_RS25715 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9F2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/2745503:HU724_RS08360 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/2745503:HU724_RS24875 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKJ6 ^@ Function|||Similarity ^@ Belongs to the MurCDEF family. Mpl subfamily.|||Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate. http://togogenome.org/gene/2745503:HU724_RS22035 ^@ http://purl.uniprot.org/uniprot/A0A9E6P915 ^@ Similarity ^@ Belongs to the SlyX family. http://togogenome.org/gene/2745503:HU724_RS01255 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbA subfamily.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS09885 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD21 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Binds 1 copper ion per subunit, denoted as copper B.|||Binds 2 heme groups per subunit, denoted as high- and low-spin.|||Membrane http://togogenome.org/gene/2745503:HU724_RS11945 ^@ http://purl.uniprot.org/uniprot/A0A9E6PF16 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS01400 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAS0 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/2745503:HU724_RS23340 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKY0 ^@ Similarity ^@ Belongs to the GST superfamily. HSP26 family. http://togogenome.org/gene/2745503:HU724_RS09255 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDQ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/2745503:HU724_RS08435 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNZ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/2745503:HU724_RS02490 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMB3 ^@ Function|||Similarity ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. http://togogenome.org/gene/2745503:HU724_RS23365 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9B7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/2745503:HU724_RS00205 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9S1 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/2745503:HU724_RS09470 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMP2 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/2745503:HU724_RS18025 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKL2 ^@ Function|||Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate. http://togogenome.org/gene/2745503:HU724_RS19735 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7D1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS06345 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBW6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/2745503:HU724_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS18045 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6G3 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/2745503:HU724_RS23715 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS06885 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD72 ^@ Similarity ^@ Belongs to the UPF0225 family. http://togogenome.org/gene/2745503:HU724_RS17520 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6P1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/2745503:HU724_RS00710 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAJ0 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/2745503:HU724_RS24145 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8K0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/2745503:HU724_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD00 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/2745503:HU724_RS08495 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CheZ family.|||Cytoplasm|||Homodimer.|||Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). http://togogenome.org/gene/2745503:HU724_RS15935 ^@ http://purl.uniprot.org/uniprot/A0A9E6P652 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/2745503:HU724_RS26540 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKU6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS17320 ^@ http://purl.uniprot.org/uniprot/A0A9E6TK73 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Cell inner membrane|||Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.|||Membrane http://togogenome.org/gene/2745503:HU724_RS09330 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCV5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/2745503:HU724_RS14555 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5B2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS20065 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7F0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS12935 ^@ http://purl.uniprot.org/uniprot/A0A9E6PFC9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NfuA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.|||Homodimer.|||Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. http://togogenome.org/gene/2745503:HU724_RS27415 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMF4 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/2745503:HU724_RS02195 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAH5 ^@ Cofactor|||Similarity ^@ Belongs to the RimK family.|||Binds 2 magnesium or manganese ions per subunit. http://togogenome.org/gene/2745503:HU724_RS09570 ^@ http://purl.uniprot.org/uniprot/A0A9E6PE71 ^@ Function|||Similarity|||Subunit ^@ Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.|||Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.|||Homotetramer; dimer of dimers.|||Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate. http://togogenome.org/gene/2745503:HU724_RS08585 ^@ http://purl.uniprot.org/uniprot/A0A9E6TP06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmD/CycX/HelD family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/2745503:HU724_RS05985 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM20 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/2745503:HU724_RS25285 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA02 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/2745503:HU724_RS24840 ^@ http://purl.uniprot.org/uniprot/A0A9E6P988 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS24160 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8U7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/2745503:HU724_RS04015 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMA2 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/2745503:HU724_RS26275 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9L8 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS04975 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS04215 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCN7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/2745503:HU724_RS08195 ^@ http://purl.uniprot.org/uniprot/A0A9E6TND0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family.|||Cell outer membrane|||Membrane|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/2745503:HU724_RS02705 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS04690 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCE1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS10250 ^@ http://purl.uniprot.org/uniprot/A0A9E6TPD5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS18450 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7M4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/2745503:HU724_RS09375 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS23235 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8I8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/2745503:HU724_RS21960 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7P9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/2745503:HU724_RS04350 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCD3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2745503:HU724_RS26690 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLR1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/2745503:HU724_RS25355 ^@ http://purl.uniprot.org/uniprot/A0A9E6P935 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/2745503:HU724_RS20875 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8F4 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/2745503:HU724_RS07540 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS24395 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8X6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS23250 ^@ http://purl.uniprot.org/uniprot/A0A9E6TK97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS23900 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9T5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/2745503:HU724_RS00580 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS03750 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB99 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/2745503:HU724_RS25260 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM22 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/2745503:HU724_RS25405 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLA0 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/2745503:HU724_RS16250 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS07155 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell outer membrane http://togogenome.org/gene/2745503:HU724_RS22870 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLM2 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/2745503:HU724_RS01695 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/2745503:HU724_RS02625 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAY1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2745503:HU724_RS08890 ^@ http://purl.uniprot.org/uniprot/A0A9E6TP25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Cob(I)alamin adenosyltransferase family.|||Cytoplasm|||Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. http://togogenome.org/gene/2745503:HU724_RS02860 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAQ2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2745503:HU724_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS18445 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6K3 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/2745503:HU724_RS26435 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9C9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MdcC family.|||Covalently binds the prosthetic group of malonate decarboxylase.|||Cytoplasm|||Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism. http://togogenome.org/gene/2745503:HU724_RS25580 ^@ http://purl.uniprot.org/uniprot/A0A9E6P934 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.|||Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. http://togogenome.org/gene/2745503:HU724_RS21395 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8L5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS25025 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers. http://togogenome.org/gene/2745503:HU724_RS20405 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7Y8 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/2745503:HU724_RS17110 ^@ http://purl.uniprot.org/uniprot/A0A9E6TPF8 ^@ Cofactor|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit. http://togogenome.org/gene/2745503:HU724_RS04045 ^@ http://purl.uniprot.org/uniprot/A0A9E6PC92 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/2745503:HU724_RS06850 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCG4 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/2745503:HU724_RS21110 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJW3 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/2745503:HU724_RS14325 ^@ http://purl.uniprot.org/uniprot/A0A9E6P587 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/2745503:HU724_RS14705 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5C2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS08770 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDE6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/2745503:HU724_RS11455 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEF1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/2745503:HU724_RS22985 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9G9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/2745503:HU724_RS12030 ^@ http://purl.uniprot.org/uniprot/A0A9E6TP33 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/2745503:HU724_RS01335 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS11315 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDR6 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/2745503:HU724_RS07415 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS25165 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLL0 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/2745503:HU724_RS08400 ^@ http://purl.uniprot.org/uniprot/A0A9E6PE67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/2745503:HU724_RS21090 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7T6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/2745503:HU724_RS07990 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCI7 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/2745503:HU724_RS02615 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAP9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/2745503:HU724_RS05195 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCN8 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/2745503:HU724_RS09215 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMM4 ^@ Similarity ^@ Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family. http://togogenome.org/gene/2745503:HU724_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/2745503:HU724_RS20090 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL18 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/2745503:HU724_RS03320 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBW5 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.|||Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.|||Homodimer.|||In the C-terminal section; belongs to the cytidylyltransferase family.|||In the N-terminal section; belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/2745503:HU724_RS10280 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEM6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS00185 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMG8 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/2745503:HU724_RS05625 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AlgJ family.|||Cell inner membrane|||Periplasm http://togogenome.org/gene/2745503:HU724_RS21615 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLB4 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/2745503:HU724_RS20795 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8C9 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/2745503:HU724_RS25295 ^@ http://purl.uniprot.org/uniprot/A0A9E6P904 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/2745503:HU724_RS18600 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6R1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS03340 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS21360 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKM3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/2745503:HU724_RS03395 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBX4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/2745503:HU724_RS26930 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKX3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/2745503:HU724_RS06805 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD64 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2745503:HU724_RS01870 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic sulfate-binding protein family.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMJ6 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase. http://togogenome.org/gene/2745503:HU724_RS23645 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PagL family.|||Cell outer membrane|||Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS27225 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB03 ^@ Function|||Similarity ^@ Belongs to the peptidase C56 family.|||Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate. http://togogenome.org/gene/2745503:HU724_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9R0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A9E6TPE8 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/2745503:HU724_RS05130 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBJ1 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/2745503:HU724_RS05860 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS09800 ^@ http://purl.uniprot.org/uniprot/A0A9E6PE91 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/2745503:HU724_RS04795 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCI4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/2745503:HU724_RS06350 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS23345 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKA0 ^@ Cofactor ^@ Binds 1 heme c group covalently per subunit. http://togogenome.org/gene/2745503:HU724_RS11880 ^@ http://purl.uniprot.org/uniprot/A0A9E6TP08 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS08325 ^@ http://purl.uniprot.org/uniprot/A0A9E6PE58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/2745503:HU724_RS23115 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8W0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/2745503:HU724_RS22095 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8V7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/2745503:HU724_RS02915 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBR1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2745503:HU724_RS21455 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLZ3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS11750 ^@ http://purl.uniprot.org/uniprot/A0A9E6PET2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS16495 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6C9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS20160 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKI1 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/2745503:HU724_RS01010 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/2745503:HU724_RS27125 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAG2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/2745503:HU724_RS25600 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS25030 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL75 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/2745503:HU724_RS01380 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAI5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/2745503:HU724_RS06360 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/2745503:HU724_RS04250 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN77 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/2745503:HU724_RS08695 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDE1 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/2745503:HU724_RS21475 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS04050 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBN5 ^@ Function|||Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.|||Catalyzes the biosynthesis of agmatine from arginine. http://togogenome.org/gene/2745503:HU724_RS03355 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB48 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/2745503:HU724_RS07965 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMZ3 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/2745503:HU724_RS22555 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLI2 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/2745503:HU724_RS20415 ^@ http://purl.uniprot.org/uniprot/A0A9E6P884 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/2745503:HU724_RS20870 ^@ http://purl.uniprot.org/uniprot/A0A9E6P843 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS22060 ^@ http://purl.uniprot.org/uniprot/A0A9E6P858 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/2745503:HU724_RS04675 ^@ http://purl.uniprot.org/uniprot/A0A9E6TME4 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/2745503:HU724_RS18105 ^@ http://purl.uniprot.org/uniprot/A0A9E6P750 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS18280 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6W6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS02515 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBL9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/2745503:HU724_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A9E6TML5 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.|||Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS02775 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBS8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/2745503:HU724_RS10955 ^@ http://purl.uniprot.org/uniprot/A0A9E6PE47 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS21780 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8R7 ^@ Similarity ^@ Belongs to the OprB family. http://togogenome.org/gene/2745503:HU724_RS14820 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJJ3 ^@ Similarity ^@ Belongs to the EfeM/EfeO family. http://togogenome.org/gene/2745503:HU724_RS20085 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKH6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS21195 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJW8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SprT family.|||Binds 1 zinc ion.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS23120 ^@ http://purl.uniprot.org/uniprot/A0A9E6P998 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane|||The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains. http://togogenome.org/gene/2745503:HU724_RS11410 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNZ3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/2745503:HU724_RS10235 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEQ7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS21950 ^@ http://purl.uniprot.org/uniprot/A0A9E6P905 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS18685 ^@ http://purl.uniprot.org/uniprot/A0A9E6P706 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/2745503:HU724_RS06505 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCI1 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/2745503:HU724_RS18085 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJZ1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2745503:HU724_RS19290 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKC8 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS26305 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLN8 ^@ PTM ^@ Binds 1 heme group per subunit. http://togogenome.org/gene/2745503:HU724_RS08605 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCQ8 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/2745503:HU724_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBE7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/2745503:HU724_RS25240 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLL4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/2745503:HU724_RS25890 ^@ http://purl.uniprot.org/uniprot/A0A9E6P976 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2745503:HU724_RS04970 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS21990 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL28 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/2745503:HU724_RS21080 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8L0 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/2745503:HU724_RS25280 ^@ http://purl.uniprot.org/uniprot/A0A9E6P926 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/2745503:HU724_RS24155 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8K1 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/2745503:HU724_RS26255 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAA4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.|||One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/2745503:HU724_RS04700 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBG5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/2745503:HU724_RS02940 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAR5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS19990 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKQ0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS05840 ^@ http://purl.uniprot.org/uniprot/A0A9E6TML7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/2745503:HU724_RS23000 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL85 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS20235 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/2745503:HU724_RS25250 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2745503:HU724_RS08190 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNE7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/2745503:HU724_RS27410 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS19775 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKF5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2745503:HU724_RS26160 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM74 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family.|||Binds 2 potassium ions per subunit.|||Dimer of dimers.|||Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS17495 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6S9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS26945 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAG1 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2745503:HU724_RS18015 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJD7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS06920 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDQ7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.|||Binds 1 [4Fe-4S] cluster.|||DNA-dependent ATPase and 5'-3' DNA helicase. http://togogenome.org/gene/2745503:HU724_RS23245 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKX7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS00220 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9R9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the exbB/tolQ family.|||Cell inner membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/2745503:HU724_RS06810 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD80 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS06270 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBV6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2745503:HU724_RS23815 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL17 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein bS18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS03630 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBX6 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/2745503:HU724_RS27175 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKZ8 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/2745503:HU724_RS24010 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL10 ^@ Function|||Similarity ^@ Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/2745503:HU724_RS23290 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8D8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Membrane|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/2745503:HU724_RS09700 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMQ9 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/2745503:HU724_RS25555 ^@ http://purl.uniprot.org/uniprot/A0A9E6P953 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/2745503:HU724_RS23665 ^@ http://purl.uniprot.org/uniprot/A0A9E6P930 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/2745503:HU724_RS18605 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7T9 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily. http://togogenome.org/gene/2745503:HU724_RS19480 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7A3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/2745503:HU724_RS04840 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLU1 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/2745503:HU724_RS04300 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS07510 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDE9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2745503:HU724_RS27300 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9M0 ^@ Similarity ^@ Belongs to the Rsd/AlgQ family. http://togogenome.org/gene/2745503:HU724_RS06670 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCE5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.|||Cell inner membrane|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/2745503:HU724_RS01795 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS08215 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDM9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Secreted http://togogenome.org/gene/2745503:HU724_RS07945 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD52 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS04310 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMM9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2745503:HU724_RS10825 ^@ http://purl.uniprot.org/uniprot/A0A9E6PE63 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/2745503:HU724_RS07535 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCY6 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/2745503:HU724_RS20785 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL56 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS17450 ^@ http://purl.uniprot.org/uniprot/A0A9E6P696 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/2745503:HU724_RS01950 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAQ3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS05260 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCD9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/2745503:HU724_RS00955 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL62 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS17075 ^@ http://purl.uniprot.org/uniprot/A0A9E6P730 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/2745503:HU724_RS07100 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS24095 ^@ http://purl.uniprot.org/uniprot/A0A9E6P984 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS25410 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM31 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS21930 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8T8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS01765 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMR9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/2745503:HU724_RS08425 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMI1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/2745503:HU724_RS07235 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS06840 ^@ http://purl.uniprot.org/uniprot/A0A9E6PC22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS25105 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL86 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/2745503:HU724_RS27165 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLW6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiD family.|||Binds 1 prenylated FMN (prenyl-FMN) per subunit.|||Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.|||Cell membrane|||Homohexamer. http://togogenome.org/gene/2745503:HU724_RS23270 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8Y1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS20915 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7Q6 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/2745503:HU724_RS20700 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJT8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS05645 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCQ2 ^@ Similarity ^@ Belongs to the D-mannuronate C5-epimerase family. http://togogenome.org/gene/2745503:HU724_RS25610 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/2745503:HU724_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB21 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS13340 ^@ http://purl.uniprot.org/uniprot/A0A9E6PED1 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS13445 ^@ http://purl.uniprot.org/uniprot/A0A9E6TPD1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/2745503:HU724_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9U9 ^@ Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/2745503:HU724_RS10990 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEN9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS21755 ^@ http://purl.uniprot.org/uniprot/A0A9E6TK03 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/2745503:HU724_RS06635 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCR3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/2745503:HU724_RS13385 ^@ http://purl.uniprot.org/uniprot/A0A9E6PFP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS00565 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM19 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/2745503:HU724_RS16560 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5Y4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS21795 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS08310 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDE3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/2745503:HU724_RS25245 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/2745503:HU724_RS08095 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD71 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/2745503:HU724_RS24450 ^@ http://purl.uniprot.org/uniprot/A0A9E6P936 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS18520 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7L0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS00510 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMI7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/2745503:HU724_RS21265 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKI9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/2745503:HU724_RS04800 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBW4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/2745503:HU724_RS21605 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJZ3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS26490 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/2745503:HU724_RS25305 ^@ http://purl.uniprot.org/uniprot/A0A9E6P901 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/2745503:HU724_RS22050 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8X9 ^@ Similarity ^@ Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. http://togogenome.org/gene/2745503:HU724_RS06395 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD34 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/2745503:HU724_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBQ0 ^@ Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/2745503:HU724_RS26840 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLU6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS07865 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD59 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS18000 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6V0 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/2745503:HU724_RS01205 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.|||Catalyzes the proton-dependent transport of glutamate and aspartate.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS09060 ^@ http://purl.uniprot.org/uniprot/A0A9E6TML4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS08470 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/2745503:HU724_RS24900 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9P5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutC family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/2745503:HU724_RS08740 ^@ http://purl.uniprot.org/uniprot/A0A9E6TP14 ^@ Cofactor|||Function|||Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/2745503:HU724_RS18350 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6L2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS03555 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBS9 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/2745503:HU724_RS21295 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8K7 ^@ Function|||Similarity ^@ Belongs to the FlgN family.|||Required for the efficient initiation of filament assembly. http://togogenome.org/gene/2745503:HU724_RS18100 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKM8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS19980 ^@ http://purl.uniprot.org/uniprot/A0A9E6P753 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/2745503:HU724_RS24775 ^@ http://purl.uniprot.org/uniprot/A0A9E6PG78 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/2745503:HU724_RS01115 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Cytoplasm|||Homodimer.|||Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. http://togogenome.org/gene/2745503:HU724_RS24615 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8R3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS08170 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCI6 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/2745503:HU724_RS03610 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMI4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/2745503:HU724_RS21705 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8Q6 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/2745503:HU724_RS17945 ^@ http://purl.uniprot.org/uniprot/A0A9E6TK39 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS08590 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/2745503:HU724_RS22970 ^@ http://purl.uniprot.org/uniprot/A0A9E6P996 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HscB family.|||Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.|||Interacts with HscA and stimulates its ATPase activity. http://togogenome.org/gene/2745503:HU724_RS05085 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMG7 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/2745503:HU724_RS21830 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKN5 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS23565 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLB3 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/2745503:HU724_RS02525 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS01330 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS10215 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD58 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/2745503:HU724_RS21275 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKM2 ^@ Function ^@ Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. http://togogenome.org/gene/2745503:HU724_RS25215 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9C1 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/2745503:HU724_RS26990 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein SsuA/TauA family.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS03730 ^@ http://purl.uniprot.org/uniprot/A0A9E6PC50 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2745503:HU724_RS04920 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLU7 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/2745503:HU724_RS08185 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD79 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/2745503:HU724_RS26000 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKR6 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/2745503:HU724_RS01085 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBG4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/2745503:HU724_RS01050 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB09 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/2745503:HU724_RS02100 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS07450 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCB6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/2745503:HU724_RS02550 ^@ http://purl.uniprot.org/uniprot/A0A9E6PC30 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/2745503:HU724_RS03125 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS05200 ^@ http://purl.uniprot.org/uniprot/A0A9E6PC13 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptA family.|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS25270 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9Y6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/2745503:HU724_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family. TsaC subfamily.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. http://togogenome.org/gene/2745503:HU724_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A9E6PC38 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/2745503:HU724_RS04930 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS15215 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5U9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAL5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/2745503:HU724_RS06110 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBT6 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/2745503:HU724_RS11095 ^@ http://purl.uniprot.org/uniprot/A0A9E6TPD9 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS21760 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKN7 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/2745503:HU724_RS26505 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9P4 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/2745503:HU724_RS25480 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS24250 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKF3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/2745503:HU724_RS20395 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKJ5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS06440 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS01045 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMM6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/2745503:HU724_RS04270 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBB8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS27215 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9X7 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/2745503:HU724_RS23025 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS25235 ^@ http://purl.uniprot.org/uniprot/A0A9E6P986 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/2745503:HU724_RS00465 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA60 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS27365 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAQ1 ^@ Function|||Similarity ^@ Belongs to the frataxin family.|||Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. http://togogenome.org/gene/2745503:HU724_RS00635 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAH8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/2745503:HU724_RS10185 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMU0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/2745503:HU724_RS25990 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLQ2 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/2745503:HU724_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN35 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/2745503:HU724_RS22565 ^@ http://purl.uniprot.org/uniprot/A0A9E6P920 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/2745503:HU724_RS26510 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9D5 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/2745503:HU724_RS25315 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/2745503:HU724_RS04805 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBD6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/2745503:HU724_RS02065 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS25880 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.|||Belongs to the SrkA/RdoA protein kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2745503:HU724_RS20885 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7K7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS00165 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLZ2 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/2745503:HU724_RS03835 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBL7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/2745503:HU724_RS23680 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8H2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolB family.|||Cell outer membrane|||Membrane|||Monomer.|||Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. http://togogenome.org/gene/2745503:HU724_RS07470 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDX1 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/2745503:HU724_RS07180 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMU7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS22005 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS00990 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB40 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/2745503:HU724_RS15690 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD). http://togogenome.org/gene/2745503:HU724_RS19400 ^@ http://purl.uniprot.org/uniprot/A0A9E6P795 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/2745503:HU724_RS25325 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKN4 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/2745503:HU724_RS08700 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCT4 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/2745503:HU724_RS20710 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS19830 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7C3 ^@ Function|||Similarity ^@ Belongs to the nucleoside phosphorylase PpnP family.|||Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. http://togogenome.org/gene/2745503:HU724_RS11745 ^@ http://purl.uniprot.org/uniprot/A0A9E6PF39 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS06310 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNL0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.|||Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.|||Cytoplasm|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS24750 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8V9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/2745503:HU724_RS13095 ^@ http://purl.uniprot.org/uniprot/A0A9E6PFE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS17525 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6A3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/2745503:HU724_RS06460 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM55 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS27450 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9P0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLK2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/2745503:HU724_RS20055 ^@ http://purl.uniprot.org/uniprot/A0A9E6P882 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/2745503:HU724_RS08100 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNE3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YciB family.|||Cell inner membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. http://togogenome.org/gene/2745503:HU724_RS25300 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAC6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2745503:HU724_RS08765 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDJ4 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Cytoplasm|||Homodimer.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/2745503:HU724_RS25310 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9G4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2745503:HU724_RS24320 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL47 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/2745503:HU724_RS24525 ^@ http://purl.uniprot.org/uniprot/A0A9E6P946 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS03375 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLH5 ^@ Function|||Similarity ^@ Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.|||Belongs to the Nudix hydrolase family. NudF subfamily. http://togogenome.org/gene/2745503:HU724_RS10140 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEQ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/2745503:HU724_RS09595 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD56 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/2745503:HU724_RS24025 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9H4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/2745503:HU724_RS25000 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA89 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. http://togogenome.org/gene/2745503:HU724_RS19515 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJL1 ^@ Function|||Similarity|||Subunit ^@ Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).|||In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.|||Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. http://togogenome.org/gene/2745503:HU724_RS06450 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsB family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/2745503:HU724_RS03455 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS19710 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS27390 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/2745503:HU724_RS02425 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS01900 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMA1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/2745503:HU724_RS25725 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAH2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/2745503:HU724_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB26 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/2745503:HU724_RS18435 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7S2 ^@ Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/2745503:HU724_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDC3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sigma-70 factor family. FliA subfamily.|||Cytoplasm|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. http://togogenome.org/gene/2745503:HU724_RS19560 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6W7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfur carrier protein TusA family.|||Cytoplasm|||Sulfur carrier protein which probably makes part of a sulfur-relay system. http://togogenome.org/gene/2745503:HU724_RS00105 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMG4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/2745503:HU724_RS22520 ^@ http://purl.uniprot.org/uniprot/A0A9E6P938 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/2745503:HU724_RS26610 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLT2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/2745503:HU724_RS20175 ^@ http://purl.uniprot.org/uniprot/A0A9E6P853 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase Slt family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS23105 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKW1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/2745503:HU724_RS18130 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6V5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS18065 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7H6 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/2745503:HU724_RS02505 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS05870 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCQ9 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/2745503:HU724_RS25535 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM35 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/2745503:HU724_RS22090 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8H5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/2745503:HU724_RS25345 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9Z6 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/2745503:HU724_RS26835 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA15 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/2745503:HU724_RS24890 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9Q4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS15590 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS19525 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS01880 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAC8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/2745503:HU724_RS00640 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS21480 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7S3 ^@ Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. http://togogenome.org/gene/2745503:HU724_RS00235 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAC9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS11040 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS25225 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAB9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/2745503:HU724_RS06065 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMN2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the OpgD/OpgG family.|||Periplasm|||Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs). http://togogenome.org/gene/2745503:HU724_RS02570 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMB8 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/2745503:HU724_RS07550 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCT5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2745503:HU724_RS16485 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6X1 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/2745503:HU724_RS08475 ^@ http://purl.uniprot.org/uniprot/A0A9E6PE78 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Cell membrane|||Membrane|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/2745503:HU724_RS23705 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9R8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/2745503:HU724_RS23110 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLP0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/2745503:HU724_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS05205 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBJ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptC family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. http://togogenome.org/gene/2745503:HU724_RS26015 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA44 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS27420 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiK family.|||Cytoplasm|||Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both. http://togogenome.org/gene/2745503:HU724_RS21270 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJX3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/2745503:HU724_RS23490 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS21190 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS24275 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9G2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/2745503:HU724_RS18020 ^@ http://purl.uniprot.org/uniprot/A0A9E6TK44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HflD family.|||Cell membrane|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLZ7 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/2745503:HU724_RS00540 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA70 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/2745503:HU724_RS03615 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLJ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/2745503:HU724_RS26620 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/2745503:HU724_RS24270 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9K6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/2745503:HU724_RS04570 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBN2 ^@ Similarity ^@ Belongs to the bleomycin resistance protein family. http://togogenome.org/gene/2745503:HU724_RS24870 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLG7 ^@ Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN. http://togogenome.org/gene/2745503:HU724_RS02780 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS00945 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/2745503:HU724_RS25335 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM26 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/2745503:HU724_RS01875 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAP3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/2745503:HU724_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMA0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/2745503:HU724_RS07035 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD98 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/2745503:HU724_RS24540 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8Q3 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/2745503:HU724_RS12210 ^@ http://purl.uniprot.org/uniprot/A0A9E6TPL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS23905 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8H0 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/2745503:HU724_RS01005 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/2745503:HU724_RS22440 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/2745503:HU724_RS26520 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9M6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS06400 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/2745503:HU724_RS19295 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKX8 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/2745503:HU724_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD11 ^@ Similarity ^@ Belongs to the UPF0260 family. http://togogenome.org/gene/2745503:HU724_RS20005 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. http://togogenome.org/gene/2745503:HU724_RS08730 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMJ8 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/2745503:HU724_RS21915 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKP5 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/2745503:HU724_RS09190 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEE4 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/2745503:HU724_RS10765 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMX2 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS00530 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9V7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Periplasm|||Secreted http://togogenome.org/gene/2745503:HU724_RS08420 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNE2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/2745503:HU724_RS03415 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.|||Cell membrane|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/2745503:HU724_RS04705 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCH5 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/2745503:HU724_RS26865 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAF5 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/2745503:HU724_RS10830 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEM3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/2745503:HU724_RS08920 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDG4 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/2745503:HU724_RS10285 ^@ http://purl.uniprot.org/uniprot/A0A9E6PED6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the trans-sulfuration enzymes family. MetZ subfamily.|||Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.|||Homotetramer. http://togogenome.org/gene/2745503:HU724_RS26815 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9T3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS04925 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMF7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/2745503:HU724_RS12995 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEV9 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/2745503:HU724_RS20135 ^@ http://purl.uniprot.org/uniprot/A0A9E6P784 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/2745503:HU724_RS05315 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMI6 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/2745503:HU724_RS25770 ^@ http://purl.uniprot.org/uniprot/A0A9E6TPH3 ^@ Function|||Similarity ^@ Belongs to the PqqA family.|||Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide. http://togogenome.org/gene/2745503:HU724_RS20370 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7A1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/2745503:HU724_RS25275 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9T7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/2745503:HU724_RS25220 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8Z4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/2745503:HU724_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS02735 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS02595 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBK7 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. http://togogenome.org/gene/2745503:HU724_RS14195 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJ51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS10085 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. http://togogenome.org/gene/2745503:HU724_RS17465 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6P9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS05245 ^@ http://purl.uniprot.org/uniprot/A0A9E6TND6 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/2745503:HU724_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM94 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/2745503:HU724_RS16545 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6Z7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/2745503:HU724_RS24755 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9S8 ^@ Similarity ^@ Belongs to the UPF0250 family. http://togogenome.org/gene/2745503:HU724_RS02435 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBD9 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/2745503:HU724_RS11320 ^@ http://purl.uniprot.org/uniprot/A0A9E6PF45 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS06785 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS24280 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8P7 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/2745503:HU724_RS12855 ^@ http://purl.uniprot.org/uniprot/A0A9E6PFB9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS18485 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKE9 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/2745503:HU724_RS11085 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMZ4 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/2745503:HU724_RS07030 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNQ8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A9E6TPC7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS06415 ^@ http://purl.uniprot.org/uniprot/A0A9E6PF62 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/2745503:HU724_RS00120 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAM4 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/2745503:HU724_RS07570 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMC3 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/2745503:HU724_RS27195 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS18755 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7P0 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/2745503:HU724_RS24845 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8U4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS06720 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell membrane|||Membrane|||Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter. http://togogenome.org/gene/2745503:HU724_RS21470 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS25020 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLH4 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/2745503:HU724_RS26025 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the threonine aldolase family.|||Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.|||Homotetramer. http://togogenome.org/gene/2745503:HU724_RS23495 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL00 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/2745503:HU724_RS26795 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAH9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS07650 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN91 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAF8 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/2745503:HU724_RS03965 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS26345 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAD1 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/2745503:HU724_RS01635 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS17620 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS26615 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLQ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell inner membrane|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/2745503:HU724_RS01395 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAH0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCE9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CysZ family.|||Cell inner membrane|||High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. http://togogenome.org/gene/2745503:HU724_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCY8 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/2745503:HU724_RS05090 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNC7 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/2745503:HU724_RS20045 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7G4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS21955 ^@ http://purl.uniprot.org/uniprot/A0A9E6P876 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CpoB family.|||Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS10230 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDD8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS25085 ^@ http://purl.uniprot.org/uniprot/A0A9E6P968 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/2745503:HU724_RS25785 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PqqD family.|||Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.|||Monomer. Interacts with PqqE. http://togogenome.org/gene/2745503:HU724_RS24260 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLW0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS20805 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8D3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/2745503:HU724_RS25830 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9M2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS07530 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD57 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48 family. BepA subfamily.|||Binds 1 zinc ion per subunit.|||Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.|||Periplasm http://togogenome.org/gene/2745503:HU724_RS26320 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS25045 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9V8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/2745503:HU724_RS27380 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB31 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS10815 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEY7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS19875 ^@ http://purl.uniprot.org/uniprot/A0A9E6P821 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/2745503:HU724_RS06390 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD23 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/2745503:HU724_RS03540 ^@ http://purl.uniprot.org/uniprot/A0A9E6TN32 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/2745503:HU724_RS08850 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS18160 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJZ6 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/2745503:HU724_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMK5 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/2745503:HU724_RS05470 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PsiE family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS23710 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8D2 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/2745503:HU724_RS24760 ^@ http://purl.uniprot.org/uniprot/A0A9E6P978 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/2745503:HU724_RS19425 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKK8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS08750 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDZ6 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/2745503:HU724_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS23895 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8H1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2745503:HU724_RS26535 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLQ6 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/2745503:HU724_RS08670 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDY7 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/2745503:HU724_RS03430 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB56 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/2745503:HU724_RS02530 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBJ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/2745503:HU724_RS05525 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMX8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2745503:HU724_RS21880 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7N8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arginine deiminase family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS06715 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD70 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS27445 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA08 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/2745503:HU724_RS24495 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLX3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/2745503:HU724_RS10260 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNQ5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS18645 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS04815 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBQ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/2745503:HU724_RS26060 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9Q1 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/2745503:HU724_RS04680 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNA4 ^@ Similarity ^@ Belongs to the UPF0125 (RnfH) family. http://togogenome.org/gene/2745503:HU724_RS08600 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbE subfamily.|||Cell inner membrane http://togogenome.org/gene/2745503:HU724_RS24265 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9H3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2745503:HU724_RS26500 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAE9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS25290 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9C5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2745503:HU724_RS19530 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7N1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.|||Cytoplasm|||Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity. http://togogenome.org/gene/2745503:HU724_RS24060 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8J0 ^@ Similarity ^@ Belongs to the N-Me-Phe pilin family. http://togogenome.org/gene/2745503:HU724_RS09625 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMQ3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. http://togogenome.org/gene/2745503:HU724_RS15555 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5Z4 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2745503:HU724_RS25385 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9H6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/2745503:HU724_RS03270 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB35 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/2745503:HU724_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS25365 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9D1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/2745503:HU724_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A9E6PE20 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/2745503:HU724_RS11310 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEA4 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/2745503:HU724_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS25800 ^@ http://purl.uniprot.org/uniprot/A0A9E6P980 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/2745503:HU724_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A9E6PC28 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.|||This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. http://togogenome.org/gene/2745503:HU724_RS02510 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/2745503:HU724_RS07850 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS22980 ^@ http://purl.uniprot.org/uniprot/A0A9E6P847 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/2745503:HU724_RS24765 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8T4 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/2745503:HU724_RS04010 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLL3 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/2745503:HU724_RS06285 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCH0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M20A family. DapE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS20565 ^@ http://purl.uniprot.org/uniprot/A0A9E6P899 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2745503:HU724_RS05055 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBT8 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/2745503:HU724_RS06485 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCQ3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/2745503:HU724_RS19350 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKK3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/2745503:HU724_RS07925 ^@ http://purl.uniprot.org/uniprot/A0A9E6PD27 ^@ Similarity ^@ Belongs to the CvfB family. http://togogenome.org/gene/2745503:HU724_RS00110 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAN8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/2745503:HU724_RS03425 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCD8 ^@ Similarity ^@ Belongs to the Smp family. http://togogenome.org/gene/2745503:HU724_RS03570 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBD7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/2745503:HU724_RS05460 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLY6 ^@ Function|||Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. http://togogenome.org/gene/2745503:HU724_RS17975 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7L5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the R-transferase family. Bpt subfamily.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. http://togogenome.org/gene/2745503:HU724_RS17145 ^@ http://purl.uniprot.org/uniprot/A0A9E6P695 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS20905 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS22645 ^@ http://purl.uniprot.org/uniprot/A0A9E6P919 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS27170 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLT8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure. http://togogenome.org/gene/2745503:HU724_RS14775 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5D8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/2745503:HU724_RS21995 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKP3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/2745503:HU724_RS13260 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEC2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane|||The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains. http://togogenome.org/gene/2745503:HU724_RS05845 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/2745503:HU724_RS18090 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJD9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2745503:HU724_RS04790 ^@ http://purl.uniprot.org/uniprot/A0A9E6PBH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/2745503:HU724_RS02105 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS15000 ^@ http://purl.uniprot.org/uniprot/A0A9E6P5E9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 4-oxalocrotonate tautomerase family.|||Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate.|||Homohexamer. http://togogenome.org/gene/2745503:HU724_RS22640 ^@ http://purl.uniprot.org/uniprot/A0A9E6P929 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS21825 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL20 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IlvD/Edd family.|||Binds 1 [4Fe-4S] cluster.|||Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate. http://togogenome.org/gene/2745503:HU724_RS01295 ^@ http://purl.uniprot.org/uniprot/A0A9E6PB81 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS21980 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7R9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbB/TolQ family.|||Cell inner membrane|||Membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/2745503:HU724_RS22910 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9G3 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/2745503:HU724_RS00195 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAU2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2745503:HU724_RS02415 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS26400 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM88 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS13680 ^@ http://purl.uniprot.org/uniprot/A0A9E6P526 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/2745503:HU724_RS20520 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8E6 ^@ Similarity ^@ Belongs to the UPF0270 family. http://togogenome.org/gene/2745503:HU724_RS26280 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9B6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS20790 ^@ http://purl.uniprot.org/uniprot/A0A9E6P832 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/2745503:HU724_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCW5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/2745503:HU724_RS23890 ^@ http://purl.uniprot.org/uniprot/A0A9E6P8W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS20545 ^@ http://purl.uniprot.org/uniprot/A0A9E6TJS8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS06195 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDH9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/2745503:HU724_RS06845 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS01715 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAM3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS00555 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/2745503:HU724_RS07970 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNW6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2745503:HU724_RS05695 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNG8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/2745503:HU724_RS25330 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL96 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/2745503:HU724_RS26550 ^@ http://purl.uniprot.org/uniprot/A0A9E6TM98 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. http://togogenome.org/gene/2745503:HU724_RS23240 ^@ http://purl.uniprot.org/uniprot/A0A9E6TL95 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/2745503:HU724_RS25780 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA14 ^@ Function|||Similarity ^@ Belongs to the PqqC family.|||Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ. http://togogenome.org/gene/2745503:HU724_RS07980 ^@ http://purl.uniprot.org/uniprot/A0A9E6PDR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/2745503:HU724_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A9E6PA58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS26180 ^@ http://purl.uniprot.org/uniprot/A0A9E6P9C0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS02495 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLD2 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/2745503:HU724_RS24680 ^@ http://purl.uniprot.org/uniprot/A0A9E6P961 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2745503:HU724_RS25495 ^@ http://purl.uniprot.org/uniprot/A0A9E6P923 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 1 iron-sulfur cluster per subunit.|||Homodimer.|||Required for insertion of 4Fe-4S clusters for at least IspG. http://togogenome.org/gene/2745503:HU724_RS09750 ^@ http://purl.uniprot.org/uniprot/A0A9E6PEJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZipA family.|||Cell inner membrane|||Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.|||Interacts with FtsZ via their C-terminal domains. http://togogenome.org/gene/2745503:HU724_RS21250 ^@ http://purl.uniprot.org/uniprot/A0A9E6P7I7 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/2745503:HU724_RS23230 ^@ http://purl.uniprot.org/uniprot/A0A9E6P879 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/2745503:HU724_RS00160 ^@ http://purl.uniprot.org/uniprot/A0A9E6PAB8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer. http://togogenome.org/gene/2745503:HU724_RS19440 ^@ http://purl.uniprot.org/uniprot/A0A9E6TKD5 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/2745503:HU724_RS25130 ^@ http://purl.uniprot.org/uniprot/A0A9E6P906 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.|||Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell membrane http://togogenome.org/gene/2745503:HU724_RS06445 ^@ http://purl.uniprot.org/uniprot/A0A9E6PCJ2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/2745503:HU724_RS00180 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLL2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/2745503:HU724_RS04665 ^@ http://purl.uniprot.org/uniprot/A0A9E6TMQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/2745503:HU724_RS10275 ^@ http://purl.uniprot.org/uniprot/A0A9E6TP98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS17955 ^@ http://purl.uniprot.org/uniprot/A0A9E6P725 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/2745503:HU724_RS22630 ^@ http://purl.uniprot.org/uniprot/A0A9E6TLI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2745503:HU724_RS17675 ^@ http://purl.uniprot.org/uniprot/A0A9E6P6Q6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2745503:HU724_RS08875 ^@ http://purl.uniprot.org/uniprot/A0A9E6TNH2 ^@ Similarity ^@ Belongs to the peptidase C40 family.