http://togogenome.org/gene/31234:GCK72_014589 ^@ http://purl.uniprot.org/uniprot/E3M633 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/31234:GCK72_008086 ^@ http://purl.uniprot.org/uniprot/E3MDL4 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_024418 ^@ http://purl.uniprot.org/uniprot/E3LE12 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/31234:GCK72_004815 ^@ http://purl.uniprot.org/uniprot/E3MZT9 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_006121 ^@ http://purl.uniprot.org/uniprot/E3M4W1 ^@ Similarity ^@ Belongs to the LECT2/MIM-1 family. http://togogenome.org/gene/31234:GCK72_010706 ^@ http://purl.uniprot.org/uniprot/E3LWZ2 ^@ Cofactor|||Function ^@ Accepts electrons from ETF and reduces ubiquinone.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/31234:GCK72_018857 ^@ http://purl.uniprot.org/uniprot/E3LZU5 ^@ Similarity ^@ Belongs to the 'GDXG' lipolytic enzyme family. http://togogenome.org/gene/31234:GCK72_018098 ^@ http://purl.uniprot.org/uniprot/E3LPQ5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_013780 ^@ http://purl.uniprot.org/uniprot/E3N3U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OST1 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/31234:GCK72_023868 ^@ http://purl.uniprot.org/uniprot/E3M2G1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_009284 ^@ http://purl.uniprot.org/uniprot/E3N090 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/31234:GCK72_007544 ^@ http://purl.uniprot.org/uniprot/E3MUK7 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/31234:GCK72_024019 ^@ http://purl.uniprot.org/uniprot/E3LCQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_015930 ^@ http://purl.uniprot.org/uniprot/E3NEV8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_015923 ^@ http://purl.uniprot.org/uniprot/E3NEV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase inhibitor family.|||Mitochondrion|||Thought to be a regulatory component of the ATP-synthesizing complex in the mitochondria. http://togogenome.org/gene/31234:GCK72_025314 ^@ http://purl.uniprot.org/uniprot/E3MUA6 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_002580 ^@ http://purl.uniprot.org/uniprot/E3LVG1 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/31234:GCK72_015687 ^@ http://purl.uniprot.org/uniprot/E3N902 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Putative Notch ligand involved in the mediation of Notch signaling. http://togogenome.org/gene/31234:GCK72_010689 ^@ http://purl.uniprot.org/uniprot/E3NH08 ^@ Similarity ^@ Belongs to the TTC21 family. http://togogenome.org/gene/31234:GCK72_002031 ^@ http://purl.uniprot.org/uniprot/E3LMB1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/31234:GCK72_002572 ^@ http://purl.uniprot.org/uniprot/E3LVH0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_001073 ^@ http://purl.uniprot.org/uniprot/E3LY27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_002638 ^@ http://purl.uniprot.org/uniprot/E3LVA3 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/31234:GCK72_003645 ^@ http://purl.uniprot.org/uniprot/E3NAU5 ^@ Similarity ^@ Belongs to the Mo25 family. http://togogenome.org/gene/31234:GCK72_008625 ^@ http://purl.uniprot.org/uniprot/E3NC93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/31234:GCK72_016954 ^@ http://purl.uniprot.org/uniprot/E3MHB8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/31234:GCK72_010149 ^@ http://purl.uniprot.org/uniprot/E3MI13 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/31234:GCK72_019371 ^@ http://purl.uniprot.org/uniprot/E3LK92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_024299 ^@ http://purl.uniprot.org/uniprot/E3LED4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM135 family.|||Membrane http://togogenome.org/gene/31234:GCK72_006137 ^@ http://purl.uniprot.org/uniprot/E3M4X7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/31234:GCK72_005332 ^@ http://purl.uniprot.org/uniprot/E3LF78 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/31234:GCK72_002368 ^@ http://purl.uniprot.org/uniprot/E3LW32 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL30 family. http://togogenome.org/gene/31234:GCK72_025555 ^@ http://purl.uniprot.org/uniprot/E3MCD7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_024773 ^@ http://purl.uniprot.org/uniprot/E3LCW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_013194 ^@ http://purl.uniprot.org/uniprot/E3NIK2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S9C family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/31234:GCK72_022258 ^@ http://purl.uniprot.org/uniprot/E3MA14 ^@ Similarity ^@ Belongs to the profilin family. http://togogenome.org/gene/31234:GCK72_024081 ^@ http://purl.uniprot.org/uniprot/E3LCF1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_009247 ^@ http://purl.uniprot.org/uniprot/E3NFY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty-acid and retinol-binding protein (FARBP) family.|||Secreted http://togogenome.org/gene/31234:GCK72_019557 ^@ http://purl.uniprot.org/uniprot/E3LLE6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_011829 ^@ http://purl.uniprot.org/uniprot/E3ML36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NEMP family.|||Nucleus inner membrane http://togogenome.org/gene/31234:GCK72_005590 ^@ http://purl.uniprot.org/uniprot/E3LFY8 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Rab family. http://togogenome.org/gene/31234:GCK72_014870 ^@ http://purl.uniprot.org/uniprot/E3M559 ^@ Similarity ^@ Belongs to the TMEM121 family. http://togogenome.org/gene/31234:GCK72_001589 ^@ http://purl.uniprot.org/uniprot/E3LND6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/31234:GCK72_024158 ^@ http://purl.uniprot.org/uniprot/E3LES2 ^@ Caution|||Similarity ^@ Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_009433 ^@ http://purl.uniprot.org/uniprot/E3LSF6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010103 ^@ http://purl.uniprot.org/uniprot/E3MD02 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_006705 ^@ http://purl.uniprot.org/uniprot/E3M117 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_014165 ^@ http://purl.uniprot.org/uniprot/E3M808 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NSE4 family.|||Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.|||Component of the SMC5-SMC6 complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_002017 ^@ http://purl.uniprot.org/uniprot/E3LMC8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_013769 ^@ http://purl.uniprot.org/uniprot/E3N3W1 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family.|||Belongs to the glucagon family. http://togogenome.org/gene/31234:GCK72_018851 ^@ http://purl.uniprot.org/uniprot/E3LZT8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/31234:GCK72_002957 ^@ http://purl.uniprot.org/uniprot/E3N942 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_008369 ^@ http://purl.uniprot.org/uniprot/E3MFQ1 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/31234:GCK72_014130 ^@ http://purl.uniprot.org/uniprot/E3NLE5 ^@ Similarity ^@ Belongs to the complex I NDUFB6 subunit family. http://togogenome.org/gene/31234:GCK72_010145 ^@ http://purl.uniprot.org/uniprot/E3MI09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ESS2 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_018262 ^@ http://purl.uniprot.org/uniprot/E3LKS1 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_006025 ^@ http://purl.uniprot.org/uniprot/E3M4L8 ^@ Similarity ^@ Belongs to the apolipoprotein L family. http://togogenome.org/gene/31234:GCK72_017535 ^@ http://purl.uniprot.org/uniprot/E3LTM2 ^@ Similarity ^@ Belongs to the acetyltransferase family. GNA1 subfamily. http://togogenome.org/gene/31234:GCK72_018764 ^@ http://purl.uniprot.org/uniprot/E3LZJ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP family.|||Membrane|||Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. http://togogenome.org/gene/31234:GCK72_017766 ^@ http://purl.uniprot.org/uniprot/E3LUB7 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/31234:GCK72_009718 ^@ http://purl.uniprot.org/uniprot/E3LT75 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_014975 ^@ http://purl.uniprot.org/uniprot/E3M5I1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_019854 ^@ http://purl.uniprot.org/uniprot/E3LJB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_023360 ^@ http://purl.uniprot.org/uniprot/E3MB29 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_018621 ^@ http://purl.uniprot.org/uniprot/E3M0B2 ^@ Similarity ^@ Belongs to the lipin family. http://togogenome.org/gene/31234:GCK72_020941 ^@ http://purl.uniprot.org/uniprot/E3MTF9 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/31234:GCK72_000629 ^@ http://purl.uniprot.org/uniprot/E3M332 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/31234:GCK72_005654 ^@ http://purl.uniprot.org/uniprot/E3LG59 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/31234:GCK72_018477 ^@ http://purl.uniprot.org/uniprot/E3LP05 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. http://togogenome.org/gene/31234:GCK72_001579 ^@ http://purl.uniprot.org/uniprot/E3LNE6 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/31234:GCK72_013754 ^@ http://purl.uniprot.org/uniprot/E3N3X4 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/31234:GCK72_003436 ^@ http://purl.uniprot.org/uniprot/E3N2P9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_012084 ^@ http://purl.uniprot.org/uniprot/E3NBB0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_024315 ^@ http://purl.uniprot.org/uniprot/E3LEB7 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_017934 ^@ http://purl.uniprot.org/uniprot/E3LUT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/31234:GCK72_017793 ^@ http://purl.uniprot.org/uniprot/E3LUE3 ^@ Similarity ^@ Belongs to the pellino family. http://togogenome.org/gene/31234:GCK72_018282 ^@ http://purl.uniprot.org/uniprot/E3LNE8 ^@ Similarity ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. http://togogenome.org/gene/31234:GCK72_005642 ^@ http://purl.uniprot.org/uniprot/E3LG44 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_019441 ^@ http://purl.uniprot.org/uniprot/E3LKS1 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_010711 ^@ http://purl.uniprot.org/uniprot/E3LWY7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS16 family.|||Late endosome membrane|||Lysosome membrane|||Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. http://togogenome.org/gene/31234:GCK72_017799 ^@ http://purl.uniprot.org/uniprot/E3LUE9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/31234:GCK72_023143 ^@ http://purl.uniprot.org/uniprot/E3MKG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/31234:GCK72_008868 ^@ http://purl.uniprot.org/uniprot/E3M8C8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_012058 ^@ http://purl.uniprot.org/uniprot/E3MK12 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.|||Binds 1 Mg(2+) ion per subunit.|||GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.|||Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_005710 ^@ http://purl.uniprot.org/uniprot/E3MN22 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_002917 ^@ http://purl.uniprot.org/uniprot/E3NKP6 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/31234:GCK72_013804 ^@ http://purl.uniprot.org/uniprot/E3NE91 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_025639 ^@ http://purl.uniprot.org/uniprot/E3MC54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COE family.|||Nucleus http://togogenome.org/gene/31234:GCK72_005916 ^@ http://purl.uniprot.org/uniprot/E3M4A8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/31234:GCK72_011072 ^@ http://purl.uniprot.org/uniprot/E3N319 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/31234:GCK72_022895 ^@ http://purl.uniprot.org/uniprot/E3MLN8 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srg family. http://togogenome.org/gene/31234:GCK72_001900 ^@ http://purl.uniprot.org/uniprot/E3LMQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_017065 ^@ http://purl.uniprot.org/uniprot/E3MDA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_018197 ^@ http://purl.uniprot.org/uniprot/E3LPZ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_002654 ^@ http://purl.uniprot.org/uniprot/E3LV77 ^@ Similarity ^@ Belongs to the CEF1 family. http://togogenome.org/gene/31234:GCK72_019326 ^@ http://purl.uniprot.org/uniprot/E3LK13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_009910 ^@ http://purl.uniprot.org/uniprot/E3LSP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 11 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_001647 ^@ http://purl.uniprot.org/uniprot/E3LLT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_014813 ^@ http://purl.uniprot.org/uniprot/E3M4Z6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Cytoplasm|||Nucleus|||tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. http://togogenome.org/gene/31234:GCK72_009682 ^@ http://purl.uniprot.org/uniprot/E3LTB7 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_024137 ^@ http://purl.uniprot.org/uniprot/E3LEU3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_003998 ^@ http://purl.uniprot.org/uniprot/E3MQK4 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_017032 ^@ http://purl.uniprot.org/uniprot/E3MD88 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_010152 ^@ http://purl.uniprot.org/uniprot/E3MI15 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/31234:GCK72_018879 ^@ http://purl.uniprot.org/uniprot/E3LZW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/31234:GCK72_009445 ^@ http://purl.uniprot.org/uniprot/E3LSE4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CLU family.|||Cytoplasm|||mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. http://togogenome.org/gene/31234:GCK72_011945 ^@ http://purl.uniprot.org/uniprot/E3MKB6 ^@ Similarity ^@ Belongs to the sorting nexin family. http://togogenome.org/gene/31234:GCK72_018214 ^@ http://purl.uniprot.org/uniprot/E3LQ17 ^@ Similarity ^@ Belongs to the dpy-30 family. http://togogenome.org/gene/31234:GCK72_006674 ^@ http://purl.uniprot.org/uniprot/E3M199 ^@ Similarity ^@ Belongs to the FAX family. http://togogenome.org/gene/31234:GCK72_001023 ^@ http://purl.uniprot.org/uniprot/E3LY74 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_005324 ^@ http://purl.uniprot.org/uniprot/E3LF71 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. http://togogenome.org/gene/31234:GCK72_017870 ^@ http://purl.uniprot.org/uniprot/E3LUL9 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/31234:GCK72_011873 ^@ http://purl.uniprot.org/uniprot/E3ML86 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/31234:GCK72_018822 ^@ http://purl.uniprot.org/uniprot/E3LZQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/31234:GCK72_025716 ^@ http://purl.uniprot.org/uniprot/E3MDX9 ^@ Caution|||Similarity ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_017103 ^@ http://purl.uniprot.org/uniprot/E3ND04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SWEET sugar transporter family.|||Cell membrane|||Golgi apparatus membrane|||Mediates sugar transport across membranes.|||Membrane http://togogenome.org/gene/31234:GCK72_008350 ^@ http://purl.uniprot.org/uniprot/E3MFS1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.|||Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/31234:GCK72_000550 ^@ http://purl.uniprot.org/uniprot/E3M3S5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_008997 ^@ http://purl.uniprot.org/uniprot/E3MWF0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL6 family. http://togogenome.org/gene/31234:GCK72_006905 ^@ http://purl.uniprot.org/uniprot/E3M1Q7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_015695 ^@ http://purl.uniprot.org/uniprot/E3N907 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_018005 ^@ http://purl.uniprot.org/uniprot/E3LPG0 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_022020 ^@ http://purl.uniprot.org/uniprot/E3MES6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC23 subfamily.|||COPII-coated vesicle membrane|||Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_022009 ^@ http://purl.uniprot.org/uniprot/E3MET9 ^@ Similarity ^@ Belongs to the ubiquitin family. http://togogenome.org/gene/31234:GCK72_007137 ^@ http://purl.uniprot.org/uniprot/E3MVF7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010428 ^@ http://purl.uniprot.org/uniprot/E3LZF9 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family. http://togogenome.org/gene/31234:GCK72_006419 ^@ http://purl.uniprot.org/uniprot/E3LQ92 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_016374 ^@ http://purl.uniprot.org/uniprot/E3MQP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP5/NOP56 family.|||nucleolus http://togogenome.org/gene/31234:GCK72_011802 ^@ http://purl.uniprot.org/uniprot/E3MSN8 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/31234:GCK72_010280 ^@ http://purl.uniprot.org/uniprot/E3MI63 ^@ Function|||Similarity ^@ Belongs to the 5'-AMP-activated protein kinase beta subunit family.|||Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). http://togogenome.org/gene/31234:GCK72_015518 ^@ http://purl.uniprot.org/uniprot/E3NCB8 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/31234:GCK72_010694 ^@ http://purl.uniprot.org/uniprot/E3LX06 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/31234:GCK72_025066 ^@ http://purl.uniprot.org/uniprot/E3MRW6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_005490 ^@ http://purl.uniprot.org/uniprot/E3LFN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDCD10 family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_015690 ^@ http://purl.uniprot.org/uniprot/E3N904 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_019541 ^@ http://purl.uniprot.org/uniprot/E3LLA3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_019899 ^@ http://purl.uniprot.org/uniprot/E3LJF5 ^@ Similarity ^@ Belongs to the FAX family. http://togogenome.org/gene/31234:GCK72_002213 ^@ http://purl.uniprot.org/uniprot/E3MGC4 ^@ Function|||Similarity ^@ Belongs to the RRF family.|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/31234:GCK72_021597 ^@ http://purl.uniprot.org/uniprot/E3N0J8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP53 family.|||May play a role in ribosome biogenesis.|||nucleolus|||nucleoplasm http://togogenome.org/gene/31234:GCK72_017922 ^@ http://purl.uniprot.org/uniprot/E3LUS8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/31234:GCK72_008261 ^@ http://purl.uniprot.org/uniprot/E3MG28 ^@ Similarity ^@ Belongs to the peptidase S28 family. http://togogenome.org/gene/31234:GCK72_002969 ^@ http://purl.uniprot.org/uniprot/E3N7I0 ^@ Similarity ^@ Belongs to the replication factor A protein 2 family. http://togogenome.org/gene/31234:GCK72_017326 ^@ http://purl.uniprot.org/uniprot/E3N1U1 ^@ Similarity ^@ Belongs to the KXD1 family. http://togogenome.org/gene/31234:GCK72_010839 ^@ http://purl.uniprot.org/uniprot/E3LWK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_004010 ^@ http://purl.uniprot.org/uniprot/E3MQL9 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/31234:GCK72_022590 ^@ http://purl.uniprot.org/uniprot/C3U548 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_000243 ^@ http://purl.uniprot.org/uniprot/E3NBU8 ^@ Function|||Similarity|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB4 subunit family.|||Complex I is composed of 45 different subunits. http://togogenome.org/gene/31234:GCK72_016159 ^@ http://purl.uniprot.org/uniprot/E3NBT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Mitochondrion|||Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits. http://togogenome.org/gene/31234:GCK72_001246 ^@ http://purl.uniprot.org/uniprot/E3LXJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC35F solute transporter family.|||Membrane http://togogenome.org/gene/31234:GCK72_016197 ^@ http://purl.uniprot.org/uniprot/E3NHW9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DIM1 family.|||Nucleus|||Plays role in pre-mRNA splicing. http://togogenome.org/gene/31234:GCK72_018444 ^@ http://purl.uniprot.org/uniprot/E3LNX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_014070 ^@ http://purl.uniprot.org/uniprot/E3M7Q9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_011115 ^@ http://purl.uniprot.org/uniprot/E3N2X3 ^@ Similarity ^@ Belongs to the cytochrome c oxidase subunit 6c family. http://togogenome.org/gene/31234:GCK72_003762 ^@ http://purl.uniprot.org/uniprot/E3MXB6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010096 ^@ http://purl.uniprot.org/uniprot/E3MCZ3 ^@ Domain|||Similarity ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family. http://togogenome.org/gene/31234:GCK72_002374 ^@ http://purl.uniprot.org/uniprot/E3LW27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM256 family.|||Membrane http://togogenome.org/gene/31234:GCK72_019438 ^@ http://purl.uniprot.org/uniprot/E3LKR8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.|||Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.|||Homotetramer. http://togogenome.org/gene/31234:GCK72_020795 ^@ http://purl.uniprot.org/uniprot/E3MBR9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_005898 ^@ http://purl.uniprot.org/uniprot/E3M491 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/31234:GCK72_008142 ^@ http://purl.uniprot.org/uniprot/E3MDF9 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/31234:GCK72_018257 ^@ http://purl.uniprot.org/uniprot/E3LKS0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_010022 ^@ http://purl.uniprot.org/uniprot/E3MCR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Caudal homeobox family.|||Nucleus http://togogenome.org/gene/31234:GCK72_020610 ^@ http://purl.uniprot.org/uniprot/E3NEK7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_001582 ^@ http://purl.uniprot.org/uniprot/E3LNE3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_009974 ^@ http://purl.uniprot.org/uniprot/E3MCL1 ^@ Subcellular Location Annotation ^@ P-body http://togogenome.org/gene/31234:GCK72_009919 ^@ http://purl.uniprot.org/uniprot/E3N9B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM147 family.|||Cell membrane|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_012109 ^@ http://purl.uniprot.org/uniprot/E3MER6 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_022198 ^@ http://purl.uniprot.org/uniprot/E3MA74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-beta family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/31234:GCK72_016463 ^@ http://purl.uniprot.org/uniprot/E3MQX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_005334 ^@ http://purl.uniprot.org/uniprot/E3LF80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_002157 ^@ http://purl.uniprot.org/uniprot/E3LLY0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_016425 ^@ http://purl.uniprot.org/uniprot/E3MQT9 ^@ Similarity ^@ Belongs to the IL-17 family. http://togogenome.org/gene/31234:GCK72_003626 ^@ http://purl.uniprot.org/uniprot/E3NAV2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_017017 ^@ http://purl.uniprot.org/uniprot/E3MD75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 27 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_014514 ^@ http://purl.uniprot.org/uniprot/E3M6B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/31234:GCK72_019961 ^@ http://purl.uniprot.org/uniprot/E3LH90 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_003602 ^@ http://purl.uniprot.org/uniprot/E3M906 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM161 family.|||Membrane http://togogenome.org/gene/31234:GCK72_014184 ^@ http://purl.uniprot.org/uniprot/E3MSR5 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/31234:GCK72_007853 ^@ http://purl.uniprot.org/uniprot/E3N294 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_014139 ^@ http://purl.uniprot.org/uniprot/E3M7Y4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/31234:GCK72_000849 ^@ http://purl.uniprot.org/uniprot/E3N4P9 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_014835 ^@ http://purl.uniprot.org/uniprot/E3M514 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/31234:GCK72_000002 ^@ http://purl.uniprot.org/uniprot/E3MT89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. LDAH family.|||Lipid droplet http://togogenome.org/gene/31234:GCK72_022266 ^@ http://purl.uniprot.org/uniprot/E3MA03 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_009535 ^@ http://purl.uniprot.org/uniprot/E3LS49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_001483 ^@ http://purl.uniprot.org/uniprot/E3N1Q3 ^@ Domain|||Function|||PTM|||Subcellular Location Annotation ^@ E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.|||The WWE domain mediates non-covalent poly(ADP-ribose)-binding.|||Ubiquitinated; autoubiquitinated.|||cytosol http://togogenome.org/gene/31234:GCK72_005534 ^@ http://purl.uniprot.org/uniprot/E3LFT0 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/31234:GCK72_019614 ^@ http://purl.uniprot.org/uniprot/E3LJP9 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/31234:GCK72_017489 ^@ http://purl.uniprot.org/uniprot/E3MNF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRM5 / TYW2 family.|||Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.|||Cytoplasm|||Mitochondrion matrix|||Monomer.|||Nucleus|||Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. http://togogenome.org/gene/31234:GCK72_024463 ^@ http://purl.uniprot.org/uniprot/E3LDW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Endoplasmic reticulum membrane|||May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.|||Membrane|||Microsome membrane http://togogenome.org/gene/31234:GCK72_023902 ^@ http://purl.uniprot.org/uniprot/E3M2K0 ^@ Similarity ^@ Belongs to the Ntn-hydrolase family. http://togogenome.org/gene/31234:GCK72_009244 ^@ http://purl.uniprot.org/uniprot/E3NFX9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOTCH family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Nucleus http://togogenome.org/gene/31234:GCK72_011285 ^@ http://purl.uniprot.org/uniprot/E3NJN2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_002191 ^@ http://purl.uniprot.org/uniprot/E3MGA0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_023125 ^@ http://purl.uniprot.org/uniprot/E3MKH7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_005122 ^@ http://purl.uniprot.org/uniprot/E3LGX3 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/31234:GCK72_017523 ^@ http://purl.uniprot.org/uniprot/E3LTL1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/31234:GCK72_025622 ^@ http://purl.uniprot.org/uniprot/E3MC70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_005938 ^@ http://purl.uniprot.org/uniprot/E3M4C9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/31234:GCK72_014537 ^@ http://purl.uniprot.org/uniprot/E3M689 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/31234:GCK72_009206 ^@ http://purl.uniprot.org/uniprot/E3N6Z3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_019900 ^@ http://purl.uniprot.org/uniprot/E3LJF6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_020300 ^@ http://purl.uniprot.org/uniprot/E3LIC2 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srg family. http://togogenome.org/gene/31234:GCK72_023149 ^@ http://purl.uniprot.org/uniprot/E3MKF4 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. http://togogenome.org/gene/31234:GCK72_005755 ^@ http://purl.uniprot.org/uniprot/E3MMX5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_010491 ^@ http://purl.uniprot.org/uniprot/E3LZ98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_023430 ^@ http://purl.uniprot.org/uniprot/E3MMK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_005609 ^@ http://purl.uniprot.org/uniprot/E3LG10 ^@ Caution|||Cofactor|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/31234:GCK72_006661 ^@ http://purl.uniprot.org/uniprot/E3M1D5 ^@ Similarity ^@ Belongs to the SIN1 family. http://togogenome.org/gene/31234:GCK72_013377 ^@ http://purl.uniprot.org/uniprot/E3N5M2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0359 family.|||Membrane http://togogenome.org/gene/31234:GCK72_009977 ^@ http://purl.uniprot.org/uniprot/E3MCL4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/31234:GCK72_015116 ^@ http://purl.uniprot.org/uniprot/E3NRE3 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/31234:GCK72_007081 ^@ http://purl.uniprot.org/uniprot/E3MVA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the carnitine/choline acetyltransferase family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/31234:GCK72_016513 ^@ http://purl.uniprot.org/uniprot/E3N784 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_003312 ^@ http://purl.uniprot.org/uniprot/E3NE39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom20 family.|||Membrane http://togogenome.org/gene/31234:GCK72_017524 ^@ http://purl.uniprot.org/uniprot/E3LTL2 ^@ Function|||Similarity ^@ Belongs to the methyltransferase TRM13 family.|||tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His). http://togogenome.org/gene/31234:GCK72_009603 ^@ http://purl.uniprot.org/uniprot/E3LRY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_014687 ^@ http://purl.uniprot.org/uniprot/E3M6V8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_020433 ^@ http://purl.uniprot.org/uniprot/E3LIS2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_018153 ^@ http://purl.uniprot.org/uniprot/E3LPW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/31234:GCK72_005320 ^@ http://purl.uniprot.org/uniprot/E3LF67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-binding oxidoreductase/transferase type 4 family.|||Peroxisome http://togogenome.org/gene/31234:GCK72_005798 ^@ http://purl.uniprot.org/uniprot/E3MMS1 ^@ Similarity ^@ Belongs to the FAX family. http://togogenome.org/gene/31234:GCK72_023802 ^@ http://purl.uniprot.org/uniprot/E3M253 ^@ Similarity ^@ Belongs to the peptidase M28 family. M28B subfamily. http://togogenome.org/gene/31234:GCK72_002741 ^@ http://purl.uniprot.org/uniprot/E3LUY1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_006445 ^@ http://purl.uniprot.org/uniprot/E3LQI7 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_009938 ^@ http://purl.uniprot.org/uniprot/E3N9A3 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_001613 ^@ http://purl.uniprot.org/uniprot/E3LNB2 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/31234:GCK72_018863 ^@ http://purl.uniprot.org/uniprot/E3LZV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the otopetrin family.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_002698 ^@ http://purl.uniprot.org/uniprot/E3LV27 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_025650 ^@ http://purl.uniprot.org/uniprot/E3MC45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_006707 ^@ http://purl.uniprot.org/uniprot/E3M115 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/31234:GCK72_007702 ^@ http://purl.uniprot.org/uniprot/E3M9J2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_001745 ^@ http://purl.uniprot.org/uniprot/E3LN13 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/31234:GCK72_014133 ^@ http://purl.uniprot.org/uniprot/E3M7X3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the pex2/pex10/pex12 family.|||Membrane|||Peroxisome membrane http://togogenome.org/gene/31234:GCK72_013773 ^@ http://purl.uniprot.org/uniprot/E3N3V6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 37 family. http://togogenome.org/gene/31234:GCK72_001945 ^@ http://purl.uniprot.org/uniprot/E3LMK9 ^@ Subcellular Location Annotation ^@ Membrane|||adherens junction|||cytoskeleton http://togogenome.org/gene/31234:GCK72_003199 ^@ http://purl.uniprot.org/uniprot/E3NFD1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_014287 ^@ http://purl.uniprot.org/uniprot/E3MT18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/31234:GCK72_016444 ^@ http://purl.uniprot.org/uniprot/E3MQV4 ^@ Function|||Similarity ^@ Belongs to the E(R) family.|||May have a role in the cell cycle. http://togogenome.org/gene/31234:GCK72_019065 ^@ http://purl.uniprot.org/uniprot/E3LKF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_000624 ^@ http://purl.uniprot.org/uniprot/E3M328 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase VIIc family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_023812 ^@ http://purl.uniprot.org/uniprot/E3M263 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/31234:GCK72_005757 ^@ http://purl.uniprot.org/uniprot/E3MMX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_011971 ^@ http://purl.uniprot.org/uniprot/E3MK87 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_005136 ^@ http://purl.uniprot.org/uniprot/E3LGY6 ^@ Similarity ^@ Belongs to the glutaminase family. http://togogenome.org/gene/31234:GCK72_006504 ^@ http://purl.uniprot.org/uniprot/E3LQC5 ^@ Caution|||Cofactor|||Function ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Metalloprotease. http://togogenome.org/gene/31234:GCK72_015675 ^@ http://purl.uniprot.org/uniprot/E3N8Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_008932 ^@ http://purl.uniprot.org/uniprot/E3N6K4 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_010068 ^@ http://purl.uniprot.org/uniprot/E3MCW6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ATPase B chain family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_012094 ^@ http://purl.uniprot.org/uniprot/E3NBB8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/31234:GCK72_009109 ^@ http://purl.uniprot.org/uniprot/E3MKS9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Component of a multi-subunit COQ enzyme complex.|||Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_024854 ^@ http://purl.uniprot.org/uniprot/E3LCC6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_021594 ^@ http://purl.uniprot.org/uniprot/E3N0K1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIF beta subunit family.|||Nucleus|||TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. http://togogenome.org/gene/31234:GCK72_023507 ^@ http://purl.uniprot.org/uniprot/E3MMQ1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_005418 ^@ http://purl.uniprot.org/uniprot/E3LFF8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL42 family. http://togogenome.org/gene/31234:GCK72_023020 ^@ http://purl.uniprot.org/uniprot/E3N6X5 ^@ Similarity ^@ Belongs to the peptidase C48 family. http://togogenome.org/gene/31234:GCK72_002621 ^@ http://purl.uniprot.org/uniprot/E3LVC0 ^@ Similarity ^@ Belongs to the GCF family. http://togogenome.org/gene/31234:GCK72_020939 ^@ http://purl.uniprot.org/uniprot/E3MTG1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_019906 ^@ http://purl.uniprot.org/uniprot/E3LJG2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_016150 ^@ http://purl.uniprot.org/uniprot/E3NMW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GAR1 family.|||Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).|||Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.|||nucleolus http://togogenome.org/gene/31234:GCK72_010359 ^@ http://purl.uniprot.org/uniprot/E3LYI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RBR family. Parkin subfamily.|||Forms an E3 ubiquitin ligase complex.|||Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.|||Mitochondrion|||cytosol http://togogenome.org/gene/31234:GCK72_012323 ^@ http://purl.uniprot.org/uniprot/E3NDP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Chromosome|||Nucleus http://togogenome.org/gene/31234:GCK72_018212 ^@ http://purl.uniprot.org/uniprot/E3LQ15 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_015503 ^@ http://purl.uniprot.org/uniprot/E3NIQ4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_001252 ^@ http://purl.uniprot.org/uniprot/E3LXJ0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/31234:GCK72_004731 ^@ http://purl.uniprot.org/uniprot/E3N386 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_018990 ^@ http://purl.uniprot.org/uniprot/E3LZZ7 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/31234:GCK72_006107 ^@ http://purl.uniprot.org/uniprot/E3M4U9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Protein transport. Probably involved in vesicular traffic. http://togogenome.org/gene/31234:GCK72_018854 ^@ http://purl.uniprot.org/uniprot/C6SUR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycoprotein hormones subunit beta family.|||Secreted http://togogenome.org/gene/31234:GCK72_016730 ^@ http://purl.uniprot.org/uniprot/E3MQC8 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_005383 ^@ http://purl.uniprot.org/uniprot/E3LFC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SARAF family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_004960 ^@ http://purl.uniprot.org/uniprot/E3LGH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CLPTM1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_008939 ^@ http://purl.uniprot.org/uniprot/E3MWJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_000665 ^@ http://purl.uniprot.org/uniprot/E3LKS0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_001142 ^@ http://purl.uniprot.org/uniprot/E3LXW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SCAMP family.|||Membrane http://togogenome.org/gene/31234:GCK72_018182 ^@ http://purl.uniprot.org/uniprot/E3LPY7 ^@ Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 27 family.|||Homodimer. http://togogenome.org/gene/31234:GCK72_025586 ^@ http://purl.uniprot.org/uniprot/E3MCA7 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/31234:GCK72_016183 ^@ http://purl.uniprot.org/uniprot/E3NBR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_013715 ^@ http://purl.uniprot.org/uniprot/E3MS52 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAN1 family.|||Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.|||Nucleus http://togogenome.org/gene/31234:GCK72_024022 ^@ http://purl.uniprot.org/uniprot/E3LCQ4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_003547 ^@ http://purl.uniprot.org/uniprot/E3M8V7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the esterase D family.|||Cytoplasm|||Serine hydrolase involved in the detoxification of formaldehyde. http://togogenome.org/gene/31234:GCK72_020944 ^@ http://purl.uniprot.org/uniprot/E3MTF5 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/31234:GCK72_005573 ^@ http://purl.uniprot.org/uniprot/E3LFX1 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/31234:GCK72_016099 ^@ http://purl.uniprot.org/uniprot/E3N9V8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex (By similarity). The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H (By similarity). The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits vah-19/Ac45 and vah-20/PRR.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.|||Vacuole membrane http://togogenome.org/gene/31234:GCK72_002095 ^@ http://purl.uniprot.org/uniprot/E3LM41 ^@ Similarity ^@ Belongs to the COG1 family. http://togogenome.org/gene/31234:GCK72_024314 ^@ http://purl.uniprot.org/uniprot/E3LEB8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010525 ^@ http://purl.uniprot.org/uniprot/E3LZ61 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_011838 ^@ http://purl.uniprot.org/uniprot/E3ML43 ^@ Subcellular Location Annotation ^@ perinuclear region http://togogenome.org/gene/31234:GCK72_017873 ^@ http://purl.uniprot.org/uniprot/E3LUM2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_006431 ^@ http://purl.uniprot.org/uniprot/E3LQK2 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_011553 ^@ http://purl.uniprot.org/uniprot/E3MIT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gemin-2 family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_020378 ^@ http://purl.uniprot.org/uniprot/E3LIK9 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/31234:GCK72_017150 ^@ http://purl.uniprot.org/uniprot/E3N574 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_018143 ^@ http://purl.uniprot.org/uniprot/E3LPV3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.|||Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Monomer.|||Nucleus http://togogenome.org/gene/31234:GCK72_025710 ^@ http://purl.uniprot.org/uniprot/E3MDX3 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_005389 ^@ http://purl.uniprot.org/uniprot/E3LFD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/31234:GCK72_018745 ^@ http://purl.uniprot.org/uniprot/E3M0Q4 ^@ Similarity ^@ Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. http://togogenome.org/gene/31234:GCK72_002280 ^@ http://purl.uniprot.org/uniprot/E3MGJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NIP7 family.|||Interacts with pre-ribosome complex.|||Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.|||nucleolus http://togogenome.org/gene/31234:GCK72_004793 ^@ http://purl.uniprot.org/uniprot/E3MZV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family.|||Nucleus http://togogenome.org/gene/31234:GCK72_019442 ^@ http://purl.uniprot.org/uniprot/E3LKS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_006903 ^@ http://purl.uniprot.org/uniprot/E3M1Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_006320 ^@ http://purl.uniprot.org/uniprot/E3LQX7 ^@ Similarity ^@ Belongs to the RAPsyn family. http://togogenome.org/gene/31234:GCK72_010508 ^@ http://purl.uniprot.org/uniprot/E3LZ80 ^@ Similarity ^@ Belongs to the CNKSR family. http://togogenome.org/gene/31234:GCK72_012076 ^@ http://purl.uniprot.org/uniprot/E3MJZ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001020 ^@ http://purl.uniprot.org/uniprot/E3LY75 ^@ Similarity ^@ Belongs to the STAM family. http://togogenome.org/gene/31234:GCK72_023880 ^@ http://purl.uniprot.org/uniprot/E3M2H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_014369 ^@ http://purl.uniprot.org/uniprot/E3MM34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_019360 ^@ http://purl.uniprot.org/uniprot/E3LK80 ^@ Similarity ^@ Belongs to the phosphatidylethanolamine-binding protein family. http://togogenome.org/gene/31234:GCK72_024733 ^@ http://purl.uniprot.org/uniprot/E3LD29 ^@ Similarity ^@ Belongs to the ATP:guanido phosphotransferase family. http://togogenome.org/gene/31234:GCK72_014755 ^@ http://purl.uniprot.org/uniprot/E3NS85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I NDUFB11 subunit family.|||Membrane http://togogenome.org/gene/31234:GCK72_019251 ^@ http://purl.uniprot.org/uniprot/E3LLH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_024338 ^@ http://purl.uniprot.org/uniprot/E3LE95|||http://purl.uniprot.org/uniprot/Q4TTR3 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_009117 ^@ http://purl.uniprot.org/uniprot/E3MKT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit A family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. http://togogenome.org/gene/31234:GCK72_025732 ^@ http://purl.uniprot.org/uniprot/E3MDZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protease inhibitor I33 family.|||Secreted http://togogenome.org/gene/31234:GCK72_014575 ^@ http://purl.uniprot.org/uniprot/E3M650 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL20 family. http://togogenome.org/gene/31234:GCK72_018730 ^@ http://purl.uniprot.org/uniprot/E3M0N7 ^@ Similarity ^@ Belongs to the GAMAD family. http://togogenome.org/gene/31234:GCK72_015120 ^@ http://purl.uniprot.org/uniprot/E3NTH3 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_005679 ^@ http://purl.uniprot.org/uniprot/E3LG85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/31234:GCK72_016141 ^@ http://purl.uniprot.org/uniprot/E3NLY0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_000819 ^@ http://purl.uniprot.org/uniprot/E3M3K5 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_014126 ^@ http://purl.uniprot.org/uniprot/E3M7W6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C54 family.|||Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_019457 ^@ http://purl.uniprot.org/uniprot/E3LKW8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005539 ^@ http://purl.uniprot.org/uniprot/E3LFT4 ^@ Function|||Similarity ^@ Belongs to the WD repeat EIF2A family.|||Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. http://togogenome.org/gene/31234:GCK72_001167 ^@ http://purl.uniprot.org/uniprot/E3LXT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/31234:GCK72_023503 ^@ http://purl.uniprot.org/uniprot/E3MMQ6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. http://togogenome.org/gene/31234:GCK72_001049 ^@ http://purl.uniprot.org/uniprot/E3LY53 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_016996 ^@ http://purl.uniprot.org/uniprot/E3MD56 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_000822 ^@ http://purl.uniprot.org/uniprot/E3M3K8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/31234:GCK72_005618 ^@ http://purl.uniprot.org/uniprot/E3LG18 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Membrane|||Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway. http://togogenome.org/gene/31234:GCK72_024881 ^@ http://purl.uniprot.org/uniprot/E3LC94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_006083 ^@ http://purl.uniprot.org/uniprot/E3M4S5 ^@ Subcellular Location Annotation ^@ centriole http://togogenome.org/gene/31234:GCK72_014973 ^@ http://purl.uniprot.org/uniprot/E3M5I0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001418 ^@ http://purl.uniprot.org/uniprot/E3MFG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL54 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_019951 ^@ http://purl.uniprot.org/uniprot/E3LJL8 ^@ Cofactor|||Similarity ^@ Belongs to the paraoxonase family.|||Binds 2 calcium ions per subunit. http://togogenome.org/gene/31234:GCK72_017573 ^@ http://purl.uniprot.org/uniprot/E3LTQ7 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_013650 ^@ http://purl.uniprot.org/uniprot/E3MSC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCTS1 family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_014625 ^@ http://purl.uniprot.org/uniprot/E3M5Z4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/31234:GCK72_005502 ^@ http://purl.uniprot.org/uniprot/E3LFP4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.|||Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.|||Nucleus http://togogenome.org/gene/31234:GCK72_025105 ^@ http://purl.uniprot.org/uniprot/E3NAT2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_020175 ^@ http://purl.uniprot.org/uniprot/E3LHW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_014416 ^@ http://purl.uniprot.org/uniprot/E3MLY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/31234:GCK72_005316 ^@ http://purl.uniprot.org/uniprot/E3LF63 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/31234:GCK72_014860 ^@ http://purl.uniprot.org/uniprot/E3M547 ^@ Similarity ^@ Belongs to the BtpA family. http://togogenome.org/gene/31234:GCK72_022259 ^@ http://purl.uniprot.org/uniprot/E3MA13 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SH3BP5 family.|||Binds preferentially to the GDP-bound form of rab-11.1.|||Cytoplasmic granule|||Golgi apparatus membrane|||Guanine nucleotide exchange factor for Rab GTPase Rab-11.1. http://togogenome.org/gene/31234:GCK72_011956 ^@ http://purl.uniprot.org/uniprot/E3MKA5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_006697 ^@ http://purl.uniprot.org/uniprot/E3M149 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_010699 ^@ http://purl.uniprot.org/uniprot/E3LWZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_016097 ^@ http://purl.uniprot.org/uniprot/E3N9V9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase C subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits. http://togogenome.org/gene/31234:GCK72_002426 ^@ http://purl.uniprot.org/uniprot/E3LVX3 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/31234:GCK72_016667 ^@ http://purl.uniprot.org/uniprot/E3NKR1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_018255 ^@ http://purl.uniprot.org/uniprot/E3LQ55 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP68 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.|||Cytoplasm|||nucleolus http://togogenome.org/gene/31234:GCK72_025085 ^@ http://purl.uniprot.org/uniprot/E3NAR3 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/31234:GCK72_005339 ^@ http://purl.uniprot.org/uniprot/E3LF84 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Nucleus http://togogenome.org/gene/31234:GCK72_005125 ^@ http://purl.uniprot.org/uniprot/E3LGX5 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_025916 ^@ http://purl.uniprot.org/uniprot/E3MUZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Golgi pH regulator (TC 1.A.38) family.|||Membrane http://togogenome.org/gene/31234:GCK72_024965 ^@ http://purl.uniprot.org/uniprot/E3MVP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_025576 ^@ http://purl.uniprot.org/uniprot/E3MCB6 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_000109 ^@ http://purl.uniprot.org/uniprot/E3N425 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_015743 ^@ http://purl.uniprot.org/uniprot/E3MXR9 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family. DDX1 subfamily.|||RNA helicase.|||The helicase domain is involved in the stimulation of RELA transcriptional activity. http://togogenome.org/gene/31234:GCK72_001061 ^@ http://purl.uniprot.org/uniprot/E3LY40 ^@ Similarity ^@ Belongs to the OSBP family. http://togogenome.org/gene/31234:GCK72_017373 ^@ http://purl.uniprot.org/uniprot/E3NCJ9 ^@ Similarity ^@ Belongs to the OSBP family. http://togogenome.org/gene/31234:GCK72_019654 ^@ http://purl.uniprot.org/uniprot/E3N7G9 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_008990 ^@ http://purl.uniprot.org/uniprot/E3MWE2 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_010934 ^@ http://purl.uniprot.org/uniprot/E3LW91 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_024365 ^@ http://purl.uniprot.org/uniprot/E3LE68 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/31234:GCK72_022260 ^@ http://purl.uniprot.org/uniprot/E3MA12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_011076 ^@ http://purl.uniprot.org/uniprot/E3N314 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_017179 ^@ http://purl.uniprot.org/uniprot/E3NPZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter. http://togogenome.org/gene/31234:GCK72_020092 ^@ http://purl.uniprot.org/uniprot/E3LHM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/31234:GCK72_000272 ^@ http://purl.uniprot.org/uniprot/E3NGE9 ^@ Cofactor ^@ Binds one Zn(2+) ion per subunit. http://togogenome.org/gene/31234:GCK72_006675 ^@ http://purl.uniprot.org/uniprot/E3M198 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM38 family.|||Membrane http://togogenome.org/gene/31234:GCK72_006087 ^@ http://purl.uniprot.org/uniprot/E3M4S8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/31234:GCK72_014388 ^@ http://purl.uniprot.org/uniprot/E3MM14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_018254 ^@ http://purl.uniprot.org/uniprot/E3LQ56 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/31234:GCK72_008306 ^@ http://purl.uniprot.org/uniprot/E3MFX8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_018862 ^@ http://purl.uniprot.org/uniprot/E3LZV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the otopetrin family.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_018154 ^@ http://purl.uniprot.org/uniprot/E3LPW3 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/31234:GCK72_010399 ^@ http://purl.uniprot.org/uniprot/E3LYD6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CND1 (condensin subunit 1) family.|||Chromosome|||Nucleus|||Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. http://togogenome.org/gene/31234:GCK72_017511 ^@ http://purl.uniprot.org/uniprot/E3LTJ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/31234:GCK72_013609 ^@ http://purl.uniprot.org/uniprot/E3MJU7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_018887 ^@ http://purl.uniprot.org/uniprot/E3LK37 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/31234:GCK72_010226 ^@ http://purl.uniprot.org/uniprot/E3MIC3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic/archaeal RNase P protein component 2 family.|||Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.|||nucleolus http://togogenome.org/gene/31234:GCK72_002395 ^@ http://purl.uniprot.org/uniprot/E3LW05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tollip family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_024874 ^@ http://purl.uniprot.org/uniprot/E3LCA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/31234:GCK72_002622 ^@ http://purl.uniprot.org/uniprot/E3LVB9 ^@ Similarity ^@ Belongs to the MFAP1 family. http://togogenome.org/gene/31234:GCK72_000654 ^@ http://purl.uniprot.org/uniprot/E3M353 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/31234:GCK72_018623 ^@ http://purl.uniprot.org/uniprot/E3M0B4 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_005756 ^@ http://purl.uniprot.org/uniprot/E3MMX4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_005434 ^@ http://purl.uniprot.org/uniprot/E3LFH3 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_014501 ^@ http://purl.uniprot.org/uniprot/E3M6D0 ^@ Similarity ^@ Belongs to the alkB family. http://togogenome.org/gene/31234:GCK72_014374 ^@ http://purl.uniprot.org/uniprot/E3MM28 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_005076 ^@ http://purl.uniprot.org/uniprot/E3LGT1 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/31234:GCK72_006682 ^@ http://purl.uniprot.org/uniprot/E3M188 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_009500 ^@ http://purl.uniprot.org/uniprot/E3LS88 ^@ Function|||PTM|||Similarity ^@ Belongs to the eIF-5A family.|||Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. http://togogenome.org/gene/31234:GCK72_023767 ^@ http://purl.uniprot.org/uniprot/E3M2W7 ^@ Similarity ^@ Belongs to the VHL family. http://togogenome.org/gene/31234:GCK72_025956 ^@ http://purl.uniprot.org/uniprot/E3MV38 ^@ Similarity ^@ Belongs to the AP-2 family. http://togogenome.org/gene/31234:GCK72_009407 ^@ http://purl.uniprot.org/uniprot/E3LSI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/31234:GCK72_008930 ^@ http://purl.uniprot.org/uniprot/E3N6K6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UTP11 family.|||Component of the ribosomal small subunit (SSU) processome.|||Involved in nucleolar processing of pre-18S ribosomal RNA.|||nucleolus http://togogenome.org/gene/31234:GCK72_000061 ^@ http://purl.uniprot.org/uniprot/E3N7P3 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_010133 ^@ http://purl.uniprot.org/uniprot/E3MD29 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/31234:GCK72_006365 ^@ http://purl.uniprot.org/uniprot/E3LQS4 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/31234:GCK72_023541 ^@ http://purl.uniprot.org/uniprot/E3NHK2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_009104 ^@ http://purl.uniprot.org/uniprot/E3MKS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/31234:GCK72_010917 ^@ http://purl.uniprot.org/uniprot/E3LWA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HEXIM family.|||Nucleus http://togogenome.org/gene/31234:GCK72_024612 ^@ http://purl.uniprot.org/uniprot/E3LDF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_010955 ^@ http://purl.uniprot.org/uniprot/E3LW73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_010742 ^@ http://purl.uniprot.org/uniprot/E3LWV2 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_017933 ^@ http://purl.uniprot.org/uniprot/E3LUT8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_014606 ^@ http://purl.uniprot.org/uniprot/E3M612 ^@ Similarity ^@ Belongs to the glycine N-acyltransferase family. http://togogenome.org/gene/31234:GCK72_020164 ^@ http://purl.uniprot.org/uniprot/E3LHV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_005246 ^@ http://purl.uniprot.org/uniprot/E3LEZ2 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_008455 ^@ http://purl.uniprot.org/uniprot/E3MY50 ^@ Similarity ^@ Belongs to the HAM1 NTPase family. http://togogenome.org/gene/31234:GCK72_022030 ^@ http://purl.uniprot.org/uniprot/E3NB58 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_014085 ^@ http://purl.uniprot.org/uniprot/E3M7S7 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_019287 ^@ http://purl.uniprot.org/uniprot/E3LJV3 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/31234:GCK72_010596 ^@ http://purl.uniprot.org/uniprot/E3LYY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_001103 ^@ http://purl.uniprot.org/uniprot/E3LXZ8 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/31234:GCK72_002279 ^@ http://purl.uniprot.org/uniprot/E3MGJ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XPF family.|||Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).|||Interacts with EME1.|||Nucleus http://togogenome.org/gene/31234:GCK72_014143 ^@ http://purl.uniprot.org/uniprot/E3M7Y8 ^@ Similarity ^@ Belongs to the GTR/RAG GTP-binding protein family. http://togogenome.org/gene/31234:GCK72_014144 ^@ http://purl.uniprot.org/uniprot/E3M7Y9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/31234:GCK72_000173 ^@ http://purl.uniprot.org/uniprot/E3NE29 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the U1 small nuclear ribonucleoprotein C family.|||Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.|||Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.|||Nucleus|||U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA. http://togogenome.org/gene/31234:GCK72_005105 ^@ http://purl.uniprot.org/uniprot/E3LGV7 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_002938 ^@ http://purl.uniprot.org/uniprot/E3N955 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_003731 ^@ http://purl.uniprot.org/uniprot/E3N2S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_010259 ^@ http://purl.uniprot.org/uniprot/E3MIF6 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_004803 ^@ http://purl.uniprot.org/uniprot/E3MZV0 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_005627 ^@ http://purl.uniprot.org/uniprot/E3LG27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL50 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_016306 ^@ http://purl.uniprot.org/uniprot/E3MYB3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_023518 ^@ http://purl.uniprot.org/uniprot/E3MMN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FARP (FMRFamide related peptide) family.|||Secreted http://togogenome.org/gene/31234:GCK72_005302 ^@ http://purl.uniprot.org/uniprot/E3LF50 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/31234:GCK72_009489 ^@ http://purl.uniprot.org/uniprot/E3LSA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/31234:GCK72_014406 ^@ http://purl.uniprot.org/uniprot/E3MLZ4 ^@ Similarity ^@ Belongs to the PPase family. http://togogenome.org/gene/31234:GCK72_020187 ^@ http://purl.uniprot.org/uniprot/E3LHX6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_002540 ^@ http://purl.uniprot.org/uniprot/E3LVK8 ^@ Subcellular Location Annotation ^@ Nucleus speckle http://togogenome.org/gene/31234:GCK72_005462 ^@ http://purl.uniprot.org/uniprot/E3LFJ7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_014413 ^@ http://purl.uniprot.org/uniprot/E3NL52 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_018083 ^@ http://purl.uniprot.org/uniprot/E3LPP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_008429 ^@ http://purl.uniprot.org/uniprot/E3NAD2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/31234:GCK72_009451 ^@ http://purl.uniprot.org/uniprot/E3LSE1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Homodimer.|||May play a role in vesicular transport from endoplasmic reticulum to Golgi.|||cis-Golgi network http://togogenome.org/gene/31234:GCK72_010692 ^@ http://purl.uniprot.org/uniprot/E3NH11 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_001089 ^@ http://purl.uniprot.org/uniprot/E3LY15 ^@ Similarity ^@ Belongs to the EAF6 family. http://togogenome.org/gene/31234:GCK72_006208 ^@ http://purl.uniprot.org/uniprot/E3LR97 ^@ Similarity ^@ Belongs to the prohibitin family. http://togogenome.org/gene/31234:GCK72_017456 ^@ http://purl.uniprot.org/uniprot/E3MNB9 ^@ Similarity ^@ Belongs to the kindlin family. http://togogenome.org/gene/31234:GCK72_000592 ^@ http://purl.uniprot.org/uniprot/E3M363 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_003292 ^@ http://purl.uniprot.org/uniprot/E3MYS1 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_024698 ^@ http://purl.uniprot.org/uniprot/E3LD63 ^@ Similarity ^@ Belongs to the protein disulfide isomerase family. http://togogenome.org/gene/31234:GCK72_020940 ^@ http://purl.uniprot.org/uniprot/E3MTG0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_005210 ^@ http://purl.uniprot.org/uniprot/E3LH60 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_005873 ^@ http://purl.uniprot.org/uniprot/E3M462 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/31234:GCK72_010820 ^@ http://purl.uniprot.org/uniprot/E3LWM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein srb family.|||Membrane http://togogenome.org/gene/31234:GCK72_024976 ^@ http://purl.uniprot.org/uniprot/E3MRM4 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_025493 ^@ http://purl.uniprot.org/uniprot/E3MJD9 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/31234:GCK72_014307 ^@ http://purl.uniprot.org/uniprot/E3NQ04 ^@ Similarity ^@ Belongs to the LovG family. http://togogenome.org/gene/31234:GCK72_016572 ^@ http://purl.uniprot.org/uniprot/E3MTV1 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/31234:GCK72_025573 ^@ http://purl.uniprot.org/uniprot/E3MCB9 ^@ Similarity ^@ Belongs to the glycine N-acyltransferase family. http://togogenome.org/gene/31234:GCK72_016651 ^@ http://purl.uniprot.org/uniprot/E3NCR7 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_001284 ^@ http://purl.uniprot.org/uniprot/E3LXF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SWP1 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/31234:GCK72_016143 ^@ http://purl.uniprot.org/uniprot/E3NIY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SWEET sugar transporter family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_025774 ^@ http://purl.uniprot.org/uniprot/E3ME42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_009011 ^@ http://purl.uniprot.org/uniprot/E3MWG6 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/31234:GCK72_009179 ^@ http://purl.uniprot.org/uniprot/E3ML05 ^@ Similarity ^@ Belongs to the FMC1 family. http://togogenome.org/gene/31234:GCK72_010717 ^@ http://purl.uniprot.org/uniprot/E3LWX9 ^@ Function|||Similarity ^@ Belongs to the hyi family.|||Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde). http://togogenome.org/gene/31234:GCK72_021595 ^@ http://purl.uniprot.org/uniprot/E3N0K0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Heterodimer of a catalytic subunit and an accessory subunit.|||Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). http://togogenome.org/gene/31234:GCK72_001171 ^@ http://purl.uniprot.org/uniprot/E3LXT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/31234:GCK72_001412 ^@ http://purl.uniprot.org/uniprot/E3MFH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/31234:GCK72_023845 ^@ http://purl.uniprot.org/uniprot/E3M297 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/31234:GCK72_025674 ^@ http://purl.uniprot.org/uniprot/E3MC16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_001849 ^@ http://purl.uniprot.org/uniprot/E3LMV9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_023166 ^@ http://purl.uniprot.org/uniprot/E3MKD6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. http://togogenome.org/gene/31234:GCK72_015981 ^@ http://purl.uniprot.org/uniprot/E3MYK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRI3 family.|||Membrane|||perinuclear region http://togogenome.org/gene/31234:GCK72_013720 ^@ http://purl.uniprot.org/uniprot/E3N417 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/31234:GCK72_018991 ^@ http://purl.uniprot.org/uniprot/E3LZZ6 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/31234:GCK72_019125 ^@ http://purl.uniprot.org/uniprot/E3LKP7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/31234:GCK72_001911 ^@ http://purl.uniprot.org/uniprot/E3LMP4 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/31234:GCK72_023586 ^@ http://purl.uniprot.org/uniprot/E3M2Y3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_002258 ^@ http://purl.uniprot.org/uniprot/E3MGH3 ^@ Similarity ^@ Belongs to the peptidase M67A family. http://togogenome.org/gene/31234:GCK72_019509 ^@ http://purl.uniprot.org/uniprot/E3LL47 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/31234:GCK72_014404 ^@ http://purl.uniprot.org/uniprot/E3MLZ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/31234:GCK72_001955 ^@ http://purl.uniprot.org/uniprot/E3LMJ9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/31234:GCK72_009256 ^@ http://purl.uniprot.org/uniprot/E3NFZ5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_005719 ^@ http://purl.uniprot.org/uniprot/E3MN12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Cytoplasm|||Homotrimer.|||Nucleus http://togogenome.org/gene/31234:GCK72_025691 ^@ http://purl.uniprot.org/uniprot/E3MBZ7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_025836 ^@ http://purl.uniprot.org/uniprot/E3MEA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_003552 ^@ http://purl.uniprot.org/uniprot/E3M8W1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane http://togogenome.org/gene/31234:GCK72_003575 ^@ http://purl.uniprot.org/uniprot/E3M8X9 ^@ Similarity ^@ Belongs to the FAM91 family. http://togogenome.org/gene/31234:GCK72_025532 ^@ http://purl.uniprot.org/uniprot/E3MCF8 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family. http://togogenome.org/gene/31234:GCK72_008423 ^@ http://purl.uniprot.org/uniprot/E3NAC9 ^@ Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Homodimer. http://togogenome.org/gene/31234:GCK72_000756 ^@ http://purl.uniprot.org/uniprot/E3M3D5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_001739 ^@ http://purl.uniprot.org/uniprot/E3LN19 ^@ Subcellular Location Annotation ^@ PML body http://togogenome.org/gene/31234:GCK72_011897 ^@ http://purl.uniprot.org/uniprot/E3MLB1 ^@ Similarity ^@ Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. http://togogenome.org/gene/31234:GCK72_002284 ^@ http://purl.uniprot.org/uniprot/E3MGK3 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/31234:GCK72_019882 ^@ http://purl.uniprot.org/uniprot/E3LJD9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_011140 ^@ http://purl.uniprot.org/uniprot/E3N924 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIA subunit 2 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_002121 ^@ http://purl.uniprot.org/uniprot/E3LM15 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_013587 ^@ http://purl.uniprot.org/uniprot/E3MJX0 ^@ Similarity ^@ Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. http://togogenome.org/gene/31234:GCK72_003969 ^@ http://purl.uniprot.org/uniprot/E3MQH2 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/31234:GCK72_011015 ^@ http://purl.uniprot.org/uniprot/E3LX36 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/31234:GCK72_024648 ^@ http://purl.uniprot.org/uniprot/E3LDB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Peroxisome http://togogenome.org/gene/31234:GCK72_017506 ^@ http://purl.uniprot.org/uniprot/E3LTJ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||Mitochondrion|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/31234:GCK72_004783 ^@ http://purl.uniprot.org/uniprot/E3MZW7 ^@ Similarity ^@ Belongs to the cytochrome P450 family.|||Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/31234:GCK72_000515 ^@ http://purl.uniprot.org/uniprot/E3M3N4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the X(+)/potassium ATPases subunit beta family.|||Cell membrane http://togogenome.org/gene/31234:GCK72_011814 ^@ http://purl.uniprot.org/uniprot/E3MSQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL40 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_000712 ^@ http://purl.uniprot.org/uniprot/E3M3B6 ^@ Caution|||Cofactor ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_020336 ^@ http://purl.uniprot.org/uniprot/E3LIG2 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/31234:GCK72_019188 ^@ http://purl.uniprot.org/uniprot/E3LL73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_016631 ^@ http://purl.uniprot.org/uniprot/E3NGS6 ^@ Similarity ^@ Belongs to the LAMTOR3 family. http://togogenome.org/gene/31234:GCK72_001624 ^@ http://purl.uniprot.org/uniprot/E3LNA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DXO/Dom3Z family.|||Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.|||Nucleus http://togogenome.org/gene/31234:GCK72_000326 ^@ http://purl.uniprot.org/uniprot/E3MX85 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/31234:GCK72_002946 ^@ http://purl.uniprot.org/uniprot/E3N948 ^@ Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. http://togogenome.org/gene/31234:GCK72_010380 ^@ http://purl.uniprot.org/uniprot/E3LYF7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_020083 ^@ http://purl.uniprot.org/uniprot/E3LHL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_007517 ^@ http://purl.uniprot.org/uniprot/E3MUP5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_014038 ^@ http://purl.uniprot.org/uniprot/E3M7M2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HRG family.|||Membrane http://togogenome.org/gene/31234:GCK72_007961 ^@ http://purl.uniprot.org/uniprot/E3N355 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/31234:GCK72_009943 ^@ http://purl.uniprot.org/uniprot/E3MCI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/31234:GCK72_019329 ^@ http://purl.uniprot.org/uniprot/E3LK15 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. http://togogenome.org/gene/31234:GCK72_018808 ^@ http://purl.uniprot.org/uniprot/E3LZP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_011963 ^@ http://purl.uniprot.org/uniprot/E3MK96 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/31234:GCK72_010852 ^@ http://purl.uniprot.org/uniprot/E3LWI5 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_024821 ^@ http://purl.uniprot.org/uniprot/E3LCL7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_017437 ^@ http://purl.uniprot.org/uniprot/E3LQ92 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_025684 ^@ http://purl.uniprot.org/uniprot/E3MC04 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||Mitochondrion|||The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/31234:GCK72_006152 ^@ http://purl.uniprot.org/uniprot/E3LRF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_019038 ^@ http://purl.uniprot.org/uniprot/E3LK98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_006292 ^@ http://purl.uniprot.org/uniprot/E3LR06 ^@ Similarity ^@ Belongs to the NAC-beta family. http://togogenome.org/gene/31234:GCK72_014244 ^@ http://purl.uniprot.org/uniprot/E3MSX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRBN family.|||Nucleus http://togogenome.org/gene/31234:GCK72_010401 ^@ http://purl.uniprot.org/uniprot/E3LZH8 ^@ Similarity ^@ Belongs to the Ntn-hydrolase family. http://togogenome.org/gene/31234:GCK72_003416 ^@ http://purl.uniprot.org/uniprot/E3N2N1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-CoA oxidase family.|||Peroxisome http://togogenome.org/gene/31234:GCK72_003114 ^@ http://purl.uniprot.org/uniprot/E3N3L5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_000908 ^@ http://purl.uniprot.org/uniprot/E3MYE9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_024016 ^@ http://purl.uniprot.org/uniprot/E3LCR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_008631 ^@ http://purl.uniprot.org/uniprot/E3NCV7 ^@ Similarity ^@ Belongs to the complex I 23 kDa subunit family. http://togogenome.org/gene/31234:GCK72_001345 ^@ http://purl.uniprot.org/uniprot/E3LX94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005557 ^@ http://purl.uniprot.org/uniprot/E3LFV4 ^@ Similarity ^@ Belongs to the histone deacetylase family. HD type 2 subfamily. http://togogenome.org/gene/31234:GCK72_003807 ^@ http://purl.uniprot.org/uniprot/E3MXE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ASF1 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_000998 ^@ http://purl.uniprot.org/uniprot/E3LY98 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_004679 ^@ http://purl.uniprot.org/uniprot/E3MHZ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELOF1 family.|||Nucleus|||Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. http://togogenome.org/gene/31234:GCK72_013852 ^@ http://purl.uniprot.org/uniprot/E3M737 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/31234:GCK72_019219 ^@ http://purl.uniprot.org/uniprot/E3LKF8 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_014572 ^@ http://purl.uniprot.org/uniprot/E3M652 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010819 ^@ http://purl.uniprot.org/uniprot/E3LWM4 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_016323 ^@ http://purl.uniprot.org/uniprot/E3N5T8 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/31234:GCK72_011906 ^@ http://purl.uniprot.org/uniprot/E3MLC1 ^@ Similarity ^@ Belongs to the SDO1/SBDS family. http://togogenome.org/gene/31234:GCK72_025472 ^@ http://purl.uniprot.org/uniprot/E3MJG2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_017212 ^@ http://purl.uniprot.org/uniprot/E3N518 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_019029 ^@ http://purl.uniprot.org/uniprot/E3LK58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_013997 ^@ http://purl.uniprot.org/uniprot/E3M7H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FARP (FMRFamide related peptide) family.|||Secreted http://togogenome.org/gene/31234:GCK72_017854 ^@ http://purl.uniprot.org/uniprot/E3LUK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Golgi apparatus|||clathrin-coated pit http://togogenome.org/gene/31234:GCK72_009704 ^@ http://purl.uniprot.org/uniprot/E3LT97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/31234:GCK72_026003 ^@ http://purl.uniprot.org/uniprot/E3NEY1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_013796 ^@ http://purl.uniprot.org/uniprot/E3NE82 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_009681 ^@ http://purl.uniprot.org/uniprot/E3LTB8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GrpE family.|||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.|||Mitochondrion matrix http://togogenome.org/gene/31234:GCK72_017877 ^@ http://purl.uniprot.org/uniprot/E3LUM8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_010304 ^@ http://purl.uniprot.org/uniprot/E3LYN9 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_002315 ^@ http://purl.uniprot.org/uniprot/E3MG61 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_017635 ^@ http://purl.uniprot.org/uniprot/E3LTX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_024848 ^@ http://purl.uniprot.org/uniprot/E3LCI5 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/31234:GCK72_006570 ^@ http://purl.uniprot.org/uniprot/E3LRP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.|||Belongs to the replication factor A protein 1 family.|||Component of the heterotrimeric canonical replication protein A complex (RPA).|||Nucleus http://togogenome.org/gene/31234:GCK72_024918 ^@ http://purl.uniprot.org/uniprot/E3MVJ7 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/31234:GCK72_013438 ^@ http://purl.uniprot.org/uniprot/E3ND71 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_013603 ^@ http://purl.uniprot.org/uniprot/E3MJV3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.|||Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP. http://togogenome.org/gene/31234:GCK72_019817 ^@ http://purl.uniprot.org/uniprot/E3LJ74 ^@ Similarity ^@ Belongs to the tRNA pseudouridine synthase TruA family. http://togogenome.org/gene/31234:GCK72_013068 ^@ http://purl.uniprot.org/uniprot/E3NKP0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic PMM family.|||Cytoplasm|||Homodimer.|||Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. http://togogenome.org/gene/31234:GCK72_010965 ^@ http://purl.uniprot.org/uniprot/E3LW64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uS10 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_014099 ^@ http://purl.uniprot.org/uniprot/E3M7U2 ^@ Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/31234:GCK72_024527 ^@ http://purl.uniprot.org/uniprot/E3LDP5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_001869 ^@ http://purl.uniprot.org/uniprot/E3LMU0 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_002541 ^@ http://purl.uniprot.org/uniprot/E3LVK7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/31234:GCK72_003860 ^@ http://purl.uniprot.org/uniprot/E3MTZ9 ^@ Similarity ^@ Belongs to the SMG9 family. http://togogenome.org/gene/31234:GCK72_019181 ^@ http://purl.uniprot.org/uniprot/E3LL06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Membrane http://togogenome.org/gene/31234:GCK72_005691 ^@ http://purl.uniprot.org/uniprot/E3MN39 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DDOST 48 kDa subunit family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). http://togogenome.org/gene/31234:GCK72_005214 ^@ http://purl.uniprot.org/uniprot/E3LH63 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/31234:GCK72_019355 ^@ http://purl.uniprot.org/uniprot/E3LK76 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_001650 ^@ http://purl.uniprot.org/uniprot/E3LLT5 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic AdoMetDC family.|||Binds 1 pyruvoyl group covalently per subunit. http://togogenome.org/gene/31234:GCK72_005387 ^@ http://purl.uniprot.org/uniprot/E3LFD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX15/CtaA family.|||Membrane http://togogenome.org/gene/31234:GCK72_013628 ^@ http://purl.uniprot.org/uniprot/E3MSF0 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphoglycerate mutase family. http://togogenome.org/gene/31234:GCK72_004180 ^@ http://purl.uniprot.org/uniprot/E3MPV4 ^@ Similarity ^@ Belongs to the GPAT/DAPAT family. http://togogenome.org/gene/31234:GCK72_000355 ^@ http://purl.uniprot.org/uniprot/E3NFG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/31234:GCK72_013564 ^@ http://purl.uniprot.org/uniprot/E3MR05 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-5 family.|||Cell membrane|||Membrane|||Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. http://togogenome.org/gene/31234:GCK72_016293 ^@ http://purl.uniprot.org/uniprot/E3MYC4 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_008283 ^@ http://purl.uniprot.org/uniprot/E3MG03 ^@ Function|||Similarity ^@ Belongs to the IPP isomerase type 1 family.|||Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). http://togogenome.org/gene/31234:GCK72_005535 ^@ http://purl.uniprot.org/uniprot/E3LFT1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_009859 ^@ http://purl.uniprot.org/uniprot/E3LSU4 ^@ Similarity ^@ Belongs to the ribose 5-phosphate isomerase family. http://togogenome.org/gene/31234:GCK72_025767 ^@ http://purl.uniprot.org/uniprot/E3ME34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the X(+)/potassium ATPases subunit beta family.|||Cell membrane http://togogenome.org/gene/31234:GCK72_017853 ^@ http://purl.uniprot.org/uniprot/E3LUK4 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/31234:GCK72_019440 ^@ http://purl.uniprot.org/uniprot/E3LKS0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_017526 ^@ http://purl.uniprot.org/uniprot/E3LTL3 ^@ Similarity ^@ Belongs to the ATPase alpha/beta chains family. http://togogenome.org/gene/31234:GCK72_016277 ^@ http://purl.uniprot.org/uniprot/E3NEU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS25 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_009194 ^@ http://purl.uniprot.org/uniprot/E3ML23 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/31234:GCK72_025352 ^@ http://purl.uniprot.org/uniprot/E3MJS9 ^@ Similarity|||Subunit ^@ Belongs to the ENDOU family.|||Monomer. http://togogenome.org/gene/31234:GCK72_006473 ^@ http://purl.uniprot.org/uniprot/E3LQF6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/31234:GCK72_001474 ^@ http://purl.uniprot.org/uniprot/E3MFB1 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/31234:GCK72_023353 ^@ http://purl.uniprot.org/uniprot/E3MB22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RAMP4 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/31234:GCK72_007110 ^@ http://purl.uniprot.org/uniprot/E3MVD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/31234:GCK72_017928 ^@ http://purl.uniprot.org/uniprot/E3LUT3 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/31234:GCK72_008389 ^@ http://purl.uniprot.org/uniprot/E3NF09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COPE family.|||Cytoplasm|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/31234:GCK72_025736 ^@ http://purl.uniprot.org/uniprot/E3ME01 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_017472 ^@ http://purl.uniprot.org/uniprot/E3MND5 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/31234:GCK72_014774 ^@ http://purl.uniprot.org/uniprot/E3NNG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELP4 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_002273 ^@ http://purl.uniprot.org/uniprot/E3MGJ0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/31234:GCK72_017211 ^@ http://purl.uniprot.org/uniprot/E3NPQ4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_017664 ^@ http://purl.uniprot.org/uniprot/E3LU05 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Putative Notch ligand involved in the mediation of Notch signaling. http://togogenome.org/gene/31234:GCK72_025561 ^@ http://purl.uniprot.org/uniprot/E3MCD1 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/31234:GCK72_021617 ^@ http://purl.uniprot.org/uniprot/E3N0I1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_024235 ^@ http://purl.uniprot.org/uniprot/E3LEJ6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. http://togogenome.org/gene/31234:GCK72_016714 ^@ http://purl.uniprot.org/uniprot/E3MQE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/31234:GCK72_019990 ^@ http://purl.uniprot.org/uniprot/E3LHB9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_016433 ^@ http://purl.uniprot.org/uniprot/E3MQU7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/31234:GCK72_010451 ^@ http://purl.uniprot.org/uniprot/E3LZD5 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_024957 ^@ http://purl.uniprot.org/uniprot/E3MVN5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005711 ^@ http://purl.uniprot.org/uniprot/E3MN21 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_000837 ^@ http://purl.uniprot.org/uniprot/E3M3M3 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/31234:GCK72_010352 ^@ http://purl.uniprot.org/uniprot/E3LYI9 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_009227 ^@ http://purl.uniprot.org/uniprot/E3N715 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_025470 ^@ http://purl.uniprot.org/uniprot/E3MJG4 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Nucleus http://togogenome.org/gene/31234:GCK72_002700 ^@ http://purl.uniprot.org/uniprot/E3LV24 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. http://togogenome.org/gene/31234:GCK72_025857 ^@ http://purl.uniprot.org/uniprot/E3MEC8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_001292 ^@ http://purl.uniprot.org/uniprot/E3LXE6 ^@ Similarity ^@ Belongs to the PTEN phosphatase protein family. http://togogenome.org/gene/31234:GCK72_024602 ^@ http://purl.uniprot.org/uniprot/E3LDG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_017843 ^@ http://purl.uniprot.org/uniprot/E3LUJ5 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/31234:GCK72_002233 ^@ http://purl.uniprot.org/uniprot/E3MGE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the akirin family.|||Nucleus http://togogenome.org/gene/31234:GCK72_006696 ^@ http://purl.uniprot.org/uniprot/E3M150 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_007200 ^@ http://purl.uniprot.org/uniprot/E3LYN8 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_004060 ^@ http://purl.uniprot.org/uniprot/E3MZI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_005089 ^@ http://purl.uniprot.org/uniprot/E3LGU2 ^@ Similarity ^@ Belongs to the AAR2 family. http://togogenome.org/gene/31234:GCK72_020082 ^@ http://purl.uniprot.org/uniprot/E3LHL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_012938 ^@ http://purl.uniprot.org/uniprot/E3N3L9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_005819 ^@ http://purl.uniprot.org/uniprot/E3M401 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/31234:GCK72_018972 ^@ http://purl.uniprot.org/uniprot/E3M017 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_013892 ^@ http://purl.uniprot.org/uniprot/E3M776 ^@ Function|||Similarity|||Subunit ^@ Belongs to the F-actin-capping protein alpha subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit. http://togogenome.org/gene/31234:GCK72_016604 ^@ http://purl.uniprot.org/uniprot/Q4TTR3 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_009201 ^@ http://purl.uniprot.org/uniprot/E3N6Z0 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/31234:GCK72_004972 ^@ http://purl.uniprot.org/uniprot/E3LGI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0389 family.|||Membrane http://togogenome.org/gene/31234:GCK72_001004 ^@ http://purl.uniprot.org/uniprot/E3LY91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SSRP1 family.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.|||Nucleus http://togogenome.org/gene/31234:GCK72_011517 ^@ http://purl.uniprot.org/uniprot/E3MIL1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_014220 ^@ http://purl.uniprot.org/uniprot/E3MSV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL51 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_024557 ^@ http://purl.uniprot.org/uniprot/E3LDL1 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_004086 ^@ http://purl.uniprot.org/uniprot/E3MZQ8 ^@ Cofactor|||Similarity ^@ Belongs to the cysteine dioxygenase family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/31234:GCK72_013337 ^@ http://purl.uniprot.org/uniprot/E3NMC6 ^@ Function|||Similarity ^@ Belongs to the 5'-AMP-activated protein kinase beta subunit family.|||Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). http://togogenome.org/gene/31234:GCK72_014653 ^@ http://purl.uniprot.org/uniprot/E3M6Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.|||Cell membrane http://togogenome.org/gene/31234:GCK72_003111 ^@ http://purl.uniprot.org/uniprot/E3NM35 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/31234:GCK72_000623 ^@ http://purl.uniprot.org/uniprot/E3M327 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_014018 ^@ http://purl.uniprot.org/uniprot/E3M7K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/31234:GCK72_017528 ^@ http://purl.uniprot.org/uniprot/E3LTL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Membrane http://togogenome.org/gene/31234:GCK72_005615 ^@ http://purl.uniprot.org/uniprot/E3LG15 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/31234:GCK72_001719 ^@ http://purl.uniprot.org/uniprot/E3LN41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/31234:GCK72_010358 ^@ http://purl.uniprot.org/uniprot/E3LYI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 29 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_013919 ^@ http://purl.uniprot.org/uniprot/E3LKS0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_011977 ^@ http://purl.uniprot.org/uniprot/E3MK81 ^@ Similarity ^@ Belongs to the GSKIP family. http://togogenome.org/gene/31234:GCK72_002410 ^@ http://purl.uniprot.org/uniprot/E3LVY8 ^@ Similarity ^@ Belongs to the TCTP family. http://togogenome.org/gene/31234:GCK72_019084 ^@ http://purl.uniprot.org/uniprot/E3LKH8 ^@ Similarity ^@ Belongs to the complex I 75 kDa subunit family. http://togogenome.org/gene/31234:GCK72_008735 ^@ http://purl.uniprot.org/uniprot/E3M874 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_020708 ^@ http://purl.uniprot.org/uniprot/E3N146 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_010639 ^@ http://purl.uniprot.org/uniprot/E3LYU0 ^@ Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/31234:GCK72_005647 ^@ http://purl.uniprot.org/uniprot/E3LG49 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017013 ^@ http://purl.uniprot.org/uniprot/E3MD71 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_006546 ^@ http://purl.uniprot.org/uniprot/E3LQ80 ^@ Similarity ^@ Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. http://togogenome.org/gene/31234:GCK72_005589 ^@ http://purl.uniprot.org/uniprot/E3LFY7 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/31234:GCK72_008691 ^@ http://purl.uniprot.org/uniprot/E3NH22 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/31234:GCK72_005045 ^@ http://purl.uniprot.org/uniprot/E3LGQ0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/31234:GCK72_006939 ^@ http://purl.uniprot.org/uniprot/E3M1M1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RED family.|||Nucleus http://togogenome.org/gene/31234:GCK72_017665 ^@ http://purl.uniprot.org/uniprot/E3LU06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty-acid and retinol-binding protein (FARBP) family.|||Secreted http://togogenome.org/gene/31234:GCK72_020961 ^@ http://purl.uniprot.org/uniprot/E3MTC9 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/31234:GCK72_023247 ^@ http://purl.uniprot.org/uniprot/E3MAR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_017995 ^@ http://purl.uniprot.org/uniprot/E3LTI1 ^@ Subcellular Location Annotation ^@ Endosome http://togogenome.org/gene/31234:GCK72_002344 ^@ http://purl.uniprot.org/uniprot/E3LUW6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS7 family. http://togogenome.org/gene/31234:GCK72_016729 ^@ http://purl.uniprot.org/uniprot/E3MQD0 ^@ Similarity ^@ Belongs to the PP1 inhibitor family. http://togogenome.org/gene/31234:GCK72_002316 ^@ http://purl.uniprot.org/uniprot/E3MG62 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/31234:GCK72_002956 ^@ http://purl.uniprot.org/uniprot/E3N943 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_024035 ^@ http://purl.uniprot.org/uniprot/E3LCP3 ^@ Similarity|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/31234:GCK72_018234 ^@ http://purl.uniprot.org/uniprot/E3LQ35 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_024029 ^@ http://purl.uniprot.org/uniprot/E3LCP8 ^@ Similarity ^@ Belongs to the SEC3 family. http://togogenome.org/gene/31234:GCK72_009387 ^@ http://purl.uniprot.org/uniprot/E3LSK4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010069 ^@ http://purl.uniprot.org/uniprot/E3MCW7 ^@ Similarity ^@ Belongs to the RING-box family. http://togogenome.org/gene/31234:GCK72_025417 ^@ http://purl.uniprot.org/uniprot/E3MJL6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_004675 ^@ http://purl.uniprot.org/uniprot/E3MHZ9 ^@ Similarity ^@ Belongs to the TTC19 family. http://togogenome.org/gene/31234:GCK72_019993 ^@ http://purl.uniprot.org/uniprot/E3LHC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_019358 ^@ http://purl.uniprot.org/uniprot/E3LK79 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_005903 ^@ http://purl.uniprot.org/uniprot/E3M495 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/31234:GCK72_006180 ^@ http://purl.uniprot.org/uniprot/E3LRC1 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/31234:GCK72_015696 ^@ http://purl.uniprot.org/uniprot/E3N908 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_014393 ^@ http://purl.uniprot.org/uniprot/E3MM09 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M8 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/31234:GCK72_005958 ^@ http://purl.uniprot.org/uniprot/E3M4F4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_005292 ^@ http://purl.uniprot.org/uniprot/E3LF39 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/31234:GCK72_010765 ^@ http://purl.uniprot.org/uniprot/E3LWT0 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family. http://togogenome.org/gene/31234:GCK72_007243 ^@ http://purl.uniprot.org/uniprot/E3MJ62 ^@ Similarity ^@ Belongs to the TAF11 family. http://togogenome.org/gene/31234:GCK72_024644 ^@ http://purl.uniprot.org/uniprot/E3LDB9 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/31234:GCK72_014299 ^@ http://purl.uniprot.org/uniprot/E3MT30 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/31234:GCK72_018471 ^@ http://purl.uniprot.org/uniprot/E3LNZ8 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/31234:GCK72_002275 ^@ http://purl.uniprot.org/uniprot/E3MGJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_017837 ^@ http://purl.uniprot.org/uniprot/E3LUI9 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_014641 ^@ http://purl.uniprot.org/uniprot/E3M701 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/31234:GCK72_022664 ^@ http://purl.uniprot.org/uniprot/E3NHB8 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_001830 ^@ http://purl.uniprot.org/uniprot/E3LMY0 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/31234:GCK72_002816 ^@ http://purl.uniprot.org/uniprot/E3MVV3 ^@ Function|||Similarity ^@ Belongs to the MPI phosphatase family.|||Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. http://togogenome.org/gene/31234:GCK72_017366 ^@ http://purl.uniprot.org/uniprot/E3NCJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_017066 ^@ http://purl.uniprot.org/uniprot/E3MDA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_011932 ^@ http://purl.uniprot.org/uniprot/E3MLE0 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_009751 ^@ http://purl.uniprot.org/uniprot/E3LT39 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_004087 ^@ http://purl.uniprot.org/uniprot/E3MZQ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/31234:GCK72_000784 ^@ http://purl.uniprot.org/uniprot/E3M3H3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TBCA family.|||Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.|||Tubulin-folding protein; involved in the early step of the tubulin folding pathway.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_002303 ^@ http://purl.uniprot.org/uniprot/E3MG50 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M24 family. SPT16 subfamily.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.|||Component of the FACT complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_021785 ^@ http://purl.uniprot.org/uniprot/E3N6F2 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/31234:GCK72_008527 ^@ http://purl.uniprot.org/uniprot/E3NHF5 ^@ Similarity ^@ Belongs to the DNA polymerase type-B-like family. http://togogenome.org/gene/31234:GCK72_024401 ^@ http://purl.uniprot.org/uniprot/E3LE31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS41 family.|||Early endosome membrane|||Endosome membrane|||Late endosome membrane|||Lysosome membrane|||Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.|||Vesicle|||clathrin-coated vesicle|||trans-Golgi network http://togogenome.org/gene/31234:GCK72_014939 ^@ http://purl.uniprot.org/uniprot/E3M5D3 ^@ Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Homotetramer. http://togogenome.org/gene/31234:GCK72_001794 ^@ http://purl.uniprot.org/uniprot/E3LLP2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/31234:GCK72_019206 ^@ http://purl.uniprot.org/uniprot/E3LL91 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. http://togogenome.org/gene/31234:GCK72_001071 ^@ http://purl.uniprot.org/uniprot/E3LY29 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/31234:GCK72_014716 ^@ http://purl.uniprot.org/uniprot/E3M6S5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.|||Belongs to the NPR3 family.|||Lysosome http://togogenome.org/gene/31234:GCK72_009734 ^@ http://purl.uniprot.org/uniprot/E3LT61 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_013580 ^@ http://purl.uniprot.org/uniprot/E3MQY6 ^@ Similarity ^@ Belongs to the beclin family. http://togogenome.org/gene/31234:GCK72_017405 ^@ http://purl.uniprot.org/uniprot/E3MN55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light intermediate chain family.|||centrosome|||cilium|||cilium axoneme|||cilium basal body http://togogenome.org/gene/31234:GCK72_013150 ^@ http://purl.uniprot.org/uniprot/E3NKC4 ^@ Similarity ^@ Belongs to the NifU family. http://togogenome.org/gene/31234:GCK72_001403 ^@ http://purl.uniprot.org/uniprot/E3MFI4 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine. http://togogenome.org/gene/31234:GCK72_019103 ^@ http://purl.uniprot.org/uniprot/E3LKM5 ^@ Function|||Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.|||Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. http://togogenome.org/gene/31234:GCK72_020232 ^@ http://purl.uniprot.org/uniprot/E3LI33 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_006738 ^@ http://purl.uniprot.org/uniprot/E3M0X9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_001102 ^@ http://purl.uniprot.org/uniprot/E3LY01 ^@ Similarity ^@ Belongs to the MAP65/ASE1 family. http://togogenome.org/gene/31234:GCK72_019343 ^@ http://purl.uniprot.org/uniprot/E3LK29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001644 ^@ http://purl.uniprot.org/uniprot/E3LLU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_006490 ^@ http://purl.uniprot.org/uniprot/E3LQD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_005973 ^@ http://purl.uniprot.org/uniprot/E3M4H1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/31234:GCK72_024084 ^@ http://purl.uniprot.org/uniprot/E3LCE8 ^@ Similarity ^@ Belongs to the WD repeat WDR91 family. http://togogenome.org/gene/31234:GCK72_019843 ^@ http://purl.uniprot.org/uniprot/E3LJA0 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_009187 ^@ http://purl.uniprot.org/uniprot/E3ML13 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_025286 ^@ http://purl.uniprot.org/uniprot/E3MUD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FARP (FMRFamide related peptide) family.|||Secreted http://togogenome.org/gene/31234:GCK72_000817 ^@ http://purl.uniprot.org/uniprot/E3M3K3 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/31234:GCK72_022904 ^@ http://purl.uniprot.org/uniprot/E3MLP5 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/31234:GCK72_024303 ^@ http://purl.uniprot.org/uniprot/E3LED0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001405 ^@ http://purl.uniprot.org/uniprot/E3MFI3 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft. http://togogenome.org/gene/31234:GCK72_014137 ^@ http://purl.uniprot.org/uniprot/E3NLF3 ^@ Similarity ^@ Belongs to the IFRD family. http://togogenome.org/gene/31234:GCK72_018269 ^@ http://purl.uniprot.org/uniprot/E3LQ68 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_020080 ^@ http://purl.uniprot.org/uniprot/E3LHL2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_004283 ^@ http://purl.uniprot.org/uniprot/E3NFS3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/31234:GCK72_015710 ^@ http://purl.uniprot.org/uniprot/E3MXW6 ^@ Similarity ^@ Belongs to the IL-17 family. http://togogenome.org/gene/31234:GCK72_014758 ^@ http://purl.uniprot.org/uniprot/E3M6M8 ^@ Similarity ^@ Belongs to the GORASP family. http://togogenome.org/gene/31234:GCK72_014341 ^@ http://purl.uniprot.org/uniprot/E3MM66 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017570 ^@ http://purl.uniprot.org/uniprot/E3LTQ4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily. http://togogenome.org/gene/31234:GCK72_023228 ^@ http://purl.uniprot.org/uniprot/E3MAP7 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/31234:GCK72_021331 ^@ http://purl.uniprot.org/uniprot/E3N8K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/31234:GCK72_005703 ^@ http://purl.uniprot.org/uniprot/E3MN27 ^@ Similarity ^@ Belongs to the CDI family. http://togogenome.org/gene/31234:GCK72_012004 ^@ http://purl.uniprot.org/uniprot/E3MK52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_008934 ^@ http://purl.uniprot.org/uniprot/E3N6K3 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_006743 ^@ http://purl.uniprot.org/uniprot/E3M0X5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_019226 ^@ http://purl.uniprot.org/uniprot/E3LLD6 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_023352 ^@ http://purl.uniprot.org/uniprot/E3MB21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-CoA oxidase family.|||Peroxisome http://togogenome.org/gene/31234:GCK72_006106 ^@ http://purl.uniprot.org/uniprot/E3M4U8 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/31234:GCK72_013949 ^@ http://purl.uniprot.org/uniprot/E3LKS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_012195 ^@ http://purl.uniprot.org/uniprot/E3MEI3 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_017175 ^@ http://purl.uniprot.org/uniprot/E3NUB5 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_024690 ^@ http://purl.uniprot.org/uniprot/E3LD71 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_016155 ^@ http://purl.uniprot.org/uniprot/E3NJW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.|||Cytoplasm|||Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity. http://togogenome.org/gene/31234:GCK72_005258 ^@ http://purl.uniprot.org/uniprot/E3LF03 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_018337 ^@ http://purl.uniprot.org/uniprot/E3LNL0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/31234:GCK72_001461 ^@ http://purl.uniprot.org/uniprot/E3MFC3 ^@ Similarity ^@ Belongs to the ANP32 family. http://togogenome.org/gene/31234:GCK72_004321 ^@ http://purl.uniprot.org/uniprot/E3NHR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein srb family.|||Membrane http://togogenome.org/gene/31234:GCK72_003481 ^@ http://purl.uniprot.org/uniprot/E3M8P3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the NnrE/AIBP family.|||Binds 1 potassium ion per subunit.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_008412 ^@ http://purl.uniprot.org/uniprot/E3NAB6 ^@ Similarity ^@ Belongs to the TIM16/PAM16 family. http://togogenome.org/gene/31234:GCK72_002685 ^@ http://purl.uniprot.org/uniprot/E3LV43 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_021596 ^@ http://purl.uniprot.org/uniprot/E3N0J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COA8 family.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_025163 ^@ http://purl.uniprot.org/uniprot/E3MZB9 ^@ Similarity ^@ Belongs to the uridine kinase family. http://togogenome.org/gene/31234:GCK72_005731 ^@ http://purl.uniprot.org/uniprot/E3MN01 ^@ Similarity ^@ Belongs to the Luc7 family. http://togogenome.org/gene/31234:GCK72_009672 ^@ http://purl.uniprot.org/uniprot/E3LTC6 ^@ Similarity ^@ Belongs to the MAM33 family. http://togogenome.org/gene/31234:GCK72_001375 ^@ http://purl.uniprot.org/uniprot/E3MFM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Membrane http://togogenome.org/gene/31234:GCK72_008823 ^@ http://purl.uniprot.org/uniprot/E3M8G5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin beta chain family.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_004908 ^@ http://purl.uniprot.org/uniprot/E3LGB9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 56 family. http://togogenome.org/gene/31234:GCK72_011624 ^@ http://purl.uniprot.org/uniprot/E3MNK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/31234:GCK72_014298 ^@ http://purl.uniprot.org/uniprot/E3MT29 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DPM3 family.|||Component of the dolichol-phosphate mannose (DPM) synthase complex.|||Endoplasmic reticulum membrane|||Membrane|||Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. http://togogenome.org/gene/31234:GCK72_009414 ^@ http://purl.uniprot.org/uniprot/E3LSH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FARP (FMRFamide related peptide) family.|||Secreted http://togogenome.org/gene/31234:GCK72_007037 ^@ http://purl.uniprot.org/uniprot/E3M175 ^@ Similarity ^@ Belongs to the helicase family. http://togogenome.org/gene/31234:GCK72_009527 ^@ http://purl.uniprot.org/uniprot/E3LS57 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/31234:GCK72_014746 ^@ http://purl.uniprot.org/uniprot/E3M6N9 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/31234:GCK72_024167 ^@ http://purl.uniprot.org/uniprot/E3LER2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_018090 ^@ http://purl.uniprot.org/uniprot/E3LPP8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_007827 ^@ http://purl.uniprot.org/uniprot/E3NB87 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_006352 ^@ http://purl.uniprot.org/uniprot/E3LQU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Late endosome membrane|||Membrane http://togogenome.org/gene/31234:GCK72_000608 ^@ http://purl.uniprot.org/uniprot/E3M3Z1 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B family. http://togogenome.org/gene/31234:GCK72_009514 ^@ http://purl.uniprot.org/uniprot/E3LS74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex (By similarity). The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H (By similarity). The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits vah-19/Ac45 and vah-20/PRR.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.|||Vacuole membrane http://togogenome.org/gene/31234:GCK72_023930 ^@ http://purl.uniprot.org/uniprot/E3NFN9 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/31234:GCK72_005160 ^@ http://purl.uniprot.org/uniprot/E3LH09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/31234:GCK72_010281 ^@ http://purl.uniprot.org/uniprot/E3MI64 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. http://togogenome.org/gene/31234:GCK72_020416 ^@ http://purl.uniprot.org/uniprot/E3LIQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMO family.|||Endoplasmic reticulum membrane|||Membrane|||Microsome membrane http://togogenome.org/gene/31234:GCK72_004652 ^@ http://purl.uniprot.org/uniprot/E3MHQ0 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/31234:GCK72_022729 ^@ http://purl.uniprot.org/uniprot/E3N6B5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_001640 ^@ http://purl.uniprot.org/uniprot/E3LLU5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA2 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_001551 ^@ http://purl.uniprot.org/uniprot/E3N1J1 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/31234:GCK72_006224 ^@ http://purl.uniprot.org/uniprot/E3LR80 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/31234:GCK72_000148 ^@ http://purl.uniprot.org/uniprot/E3NE18 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/31234:GCK72_002180 ^@ http://purl.uniprot.org/uniprot/E3MG90 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/31234:GCK72_016468 ^@ http://purl.uniprot.org/uniprot/E3MQX7 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_023158 ^@ http://purl.uniprot.org/uniprot/E3MKE4 ^@ Similarity ^@ Belongs to the NDRG family. http://togogenome.org/gene/31234:GCK72_018685 ^@ http://purl.uniprot.org/uniprot/E3M0I5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_018702 ^@ http://purl.uniprot.org/uniprot/E3M0K6 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/31234:GCK72_009192 ^@ http://purl.uniprot.org/uniprot/E3ML20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_002061 ^@ http://purl.uniprot.org/uniprot/E3LM81 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/31234:GCK72_009103 ^@ http://purl.uniprot.org/uniprot/E3MKS0 ^@ Similarity ^@ Belongs to the peptidase S28 family. http://togogenome.org/gene/31234:GCK72_017318 ^@ http://purl.uniprot.org/uniprot/E3LKF8 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_011033 ^@ http://purl.uniprot.org/uniprot/E3LX19 ^@ Similarity ^@ Belongs to the SBNO family. http://togogenome.org/gene/31234:GCK72_009189 ^@ http://purl.uniprot.org/uniprot/E3ML16 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Nth/MutY family.|||Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.|||Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.|||Mitochondrion|||Nucleus http://togogenome.org/gene/31234:GCK72_005424 ^@ http://purl.uniprot.org/uniprot/E3LFG4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CybS family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_004991 ^@ http://purl.uniprot.org/uniprot/E3LGK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_009296 ^@ http://purl.uniprot.org/uniprot/E3N082 ^@ Similarity ^@ Belongs to the CWC26 family. http://togogenome.org/gene/31234:GCK72_011781 ^@ http://purl.uniprot.org/uniprot/E3MSL6 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. GMF subfamily. http://togogenome.org/gene/31234:GCK72_013452 ^@ http://purl.uniprot.org/uniprot/E3ND84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_020605 ^@ http://purl.uniprot.org/uniprot/E3NEL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_025386 ^@ http://purl.uniprot.org/uniprot/E3MJP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sorting nexin family.|||Cytoplasmic vesicle membrane|||Early endosome|||Endosome|||Membrane http://togogenome.org/gene/31234:GCK72_002008 ^@ http://purl.uniprot.org/uniprot/E3LMD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_018428 ^@ http://purl.uniprot.org/uniprot/E3LNW0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_010183 ^@ http://purl.uniprot.org/uniprot/E3MIA6 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase family. http://togogenome.org/gene/31234:GCK72_009779 ^@ http://purl.uniprot.org/uniprot/E3LT21 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. HEN1 family. http://togogenome.org/gene/31234:GCK72_002235 ^@ http://purl.uniprot.org/uniprot/E3MGE8 ^@ Similarity ^@ Belongs to the ARS2 family. http://togogenome.org/gene/31234:GCK72_005894 ^@ http://purl.uniprot.org/uniprot/E3M487 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_024625 ^@ http://purl.uniprot.org/uniprot/E3LDE0 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_017038 ^@ http://purl.uniprot.org/uniprot/E3MD94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_024622 ^@ http://purl.uniprot.org/uniprot/E3LDE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_001684 ^@ http://purl.uniprot.org/uniprot/E3LN78 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_016379 ^@ http://purl.uniprot.org/uniprot/E3MQP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/31234:GCK72_022955 ^@ http://purl.uniprot.org/uniprot/E3N8E1 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_008359 ^@ http://purl.uniprot.org/uniprot/E3MFR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDK2AP family.|||Nucleus http://togogenome.org/gene/31234:GCK72_019047 ^@ http://purl.uniprot.org/uniprot/E3LKA8 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/31234:GCK72_002081 ^@ http://purl.uniprot.org/uniprot/E3LM60 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/31234:GCK72_006902 ^@ http://purl.uniprot.org/uniprot/E3M1R0 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/31234:GCK72_023566 ^@ http://purl.uniprot.org/uniprot/E3M2T8 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_004978 ^@ http://purl.uniprot.org/uniprot/E3LGI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMCO1 family.|||Calcium-selective channel required to prevent calcium stores from overfilling.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_024332 ^@ http://purl.uniprot.org/uniprot/E3LEA0 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/31234:GCK72_018261 ^@ http://purl.uniprot.org/uniprot/E3LKS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_012077 ^@ http://purl.uniprot.org/uniprot/E3MJY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_006651 ^@ http://purl.uniprot.org/uniprot/E3LRG8 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. http://togogenome.org/gene/31234:GCK72_000420 ^@ http://purl.uniprot.org/uniprot/E3NCM1 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_001480 ^@ http://purl.uniprot.org/uniprot/E3MFA4 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/31234:GCK72_017562 ^@ http://purl.uniprot.org/uniprot/E3LTP7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/31234:GCK72_021613 ^@ http://purl.uniprot.org/uniprot/E3N0I6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_003664 ^@ http://purl.uniprot.org/uniprot/E3NB15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_016991 ^@ http://purl.uniprot.org/uniprot/E3MD49 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_002174 ^@ http://purl.uniprot.org/uniprot/E3MG81 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_005476 ^@ http://purl.uniprot.org/uniprot/E3LFL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Membrane http://togogenome.org/gene/31234:GCK72_014419 ^@ http://purl.uniprot.org/uniprot/E3MLX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP18 family.|||Nucleus speckle http://togogenome.org/gene/31234:GCK72_018190 ^@ http://purl.uniprot.org/uniprot/E3LPZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_002078 ^@ http://purl.uniprot.org/uniprot/E3LM63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TAM41 family.|||Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_014600 ^@ http://purl.uniprot.org/uniprot/E3M618 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_006614 ^@ http://purl.uniprot.org/uniprot/E3LRK4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_013467 ^@ http://purl.uniprot.org/uniprot/E3NDA4 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_014104 ^@ http://purl.uniprot.org/uniprot/E3M7U7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/31234:GCK72_025278 ^@ http://purl.uniprot.org/uniprot/E3MUE2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_018259 ^@ http://purl.uniprot.org/uniprot/E3LKS1 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_005678 ^@ http://purl.uniprot.org/uniprot/E3LG84 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/31234:GCK72_018712 ^@ http://purl.uniprot.org/uniprot/E3M0L7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DXO/Dom3Z family.|||Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.|||Nucleus http://togogenome.org/gene/31234:GCK72_007933 ^@ http://purl.uniprot.org/uniprot/E3N332 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_000174 ^@ http://purl.uniprot.org/uniprot/E3NE30 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the U1 small nuclear ribonucleoprotein C family.|||Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.|||Nucleus|||U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA. http://togogenome.org/gene/31234:GCK72_006192 ^@ http://purl.uniprot.org/uniprot/E3LRB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OB-RGRP/VPS55 family.|||Membrane http://togogenome.org/gene/31234:GCK72_001227 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_004919 ^@ http://purl.uniprot.org/uniprot/E3LGD1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL24 family. http://togogenome.org/gene/31234:GCK72_022123 ^@ http://purl.uniprot.org/uniprot/E3MAF5 ^@ Function|||Similarity ^@ Belongs to the MPI phosphatase family.|||Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. http://togogenome.org/gene/31234:GCK72_013854 ^@ http://purl.uniprot.org/uniprot/E3M744 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP23 family.|||Membrane http://togogenome.org/gene/31234:GCK72_013258 ^@ http://purl.uniprot.org/uniprot/E3MRM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_022784 ^@ http://purl.uniprot.org/uniprot/E3NKT3 ^@ Similarity ^@ Belongs to the AP-2 family. http://togogenome.org/gene/31234:GCK72_001718 ^@ http://purl.uniprot.org/uniprot/E3LN42 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/31234:GCK72_014135 ^@ http://purl.uniprot.org/uniprot/E3NLF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_017536 ^@ http://purl.uniprot.org/uniprot/E3LTM3 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruD family. http://togogenome.org/gene/31234:GCK72_023461 ^@ http://purl.uniprot.org/uniprot/E3MMG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Membrane http://togogenome.org/gene/31234:GCK72_005283 ^@ http://purl.uniprot.org/uniprot/E3LF28 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/31234:GCK72_023710 ^@ http://purl.uniprot.org/uniprot/E3M2N5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_008698 ^@ http://purl.uniprot.org/uniprot/E3NH27 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_011640 ^@ http://purl.uniprot.org/uniprot/E3MNI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sphingomyelin synthase family.|||Membrane http://togogenome.org/gene/31234:GCK72_018122 ^@ http://purl.uniprot.org/uniprot/E3LPT2 ^@ Similarity ^@ Belongs to the vinculin/alpha-catenin family. http://togogenome.org/gene/31234:GCK72_013231 ^@ http://purl.uniprot.org/uniprot/E3N9Z9 ^@ Similarity ^@ Belongs to the DPH3 family. http://togogenome.org/gene/31234:GCK72_010663 ^@ http://purl.uniprot.org/uniprot/E3LYR2 ^@ Similarity ^@ Belongs to the dynactin subunit 2 family. http://togogenome.org/gene/31234:GCK72_020184 ^@ http://purl.uniprot.org/uniprot/E3LHX3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_013521 ^@ http://purl.uniprot.org/uniprot/E3MR54 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_006134 ^@ http://purl.uniprot.org/uniprot/E3M4X4 ^@ Similarity ^@ Belongs to the CTNNBIP1 family. http://togogenome.org/gene/31234:GCK72_002653 ^@ http://purl.uniprot.org/uniprot/E3LV78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_010370 ^@ http://purl.uniprot.org/uniprot/E3LYG7 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/31234:GCK72_013959 ^@ http://purl.uniprot.org/uniprot/E3M7E1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_010983 ^@ http://purl.uniprot.org/uniprot/E3LX70 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_015838 ^@ http://purl.uniprot.org/uniprot/E3N5G8 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_005661 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_005623 ^@ http://purl.uniprot.org/uniprot/E3LG23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_018298 ^@ http://purl.uniprot.org/uniprot/E3LNH3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_001518 ^@ http://purl.uniprot.org/uniprot/E3N1M1 ^@ Function|||Subcellular Location Annotation ^@ In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/31234:GCK72_018007 ^@ http://purl.uniprot.org/uniprot/E3LPG2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_002416 ^@ http://purl.uniprot.org/uniprot/E3LVY2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_002458 ^@ http://purl.uniprot.org/uniprot/E3LVU2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_011040 ^@ http://purl.uniprot.org/uniprot/E3LX12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane http://togogenome.org/gene/31234:GCK72_022221 ^@ http://purl.uniprot.org/uniprot/E3MA52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_014160 ^@ http://purl.uniprot.org/uniprot/E3M803 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_020754 ^@ http://purl.uniprot.org/uniprot/E3MB62 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_007193 ^@ http://purl.uniprot.org/uniprot/E3MJ53 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_025357 ^@ http://purl.uniprot.org/uniprot/E3MJS2 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/31234:GCK72_017864 ^@ http://purl.uniprot.org/uniprot/E3LUL3 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_019394 ^@ http://purl.uniprot.org/uniprot/E3LKE6 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_009442 ^@ http://purl.uniprot.org/uniprot/E3LSE7 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/31234:GCK72_018130 ^@ http://purl.uniprot.org/uniprot/E3LPT9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/31234:GCK72_024734 ^@ http://purl.uniprot.org/uniprot/E3LD28 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 5'-AMP-activated protein kinase beta subunit family.|||Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).|||Nucleus http://togogenome.org/gene/31234:GCK72_014812 ^@ http://purl.uniprot.org/uniprot/E3M4Z5 ^@ Similarity ^@ Belongs to the learning-associated protein family. http://togogenome.org/gene/31234:GCK72_014714 ^@ http://purl.uniprot.org/uniprot/E3M6S7 ^@ Similarity ^@ Belongs to the CENP-X/MHF2 family. http://togogenome.org/gene/31234:GCK72_017759 ^@ http://purl.uniprot.org/uniprot/E3LUB1 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/31234:GCK72_005447 ^@ http://purl.uniprot.org/uniprot/E3LFI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC9 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/31234:GCK72_013983 ^@ http://purl.uniprot.org/uniprot/E3M7G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PUR DNA-binding protein family.|||Nucleus http://togogenome.org/gene/31234:GCK72_017978 ^@ http://purl.uniprot.org/uniprot/E3LTG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alkaline ceramidase family.|||Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.|||Membrane http://togogenome.org/gene/31234:GCK72_002405 ^@ http://purl.uniprot.org/uniprot/E3LVZ4 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/31234:GCK72_005338 ^@ http://purl.uniprot.org/uniprot/E3LF83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Catalyzes the transfer of galactose onto proteins or lipids.|||Membrane http://togogenome.org/gene/31234:GCK72_002167 ^@ http://purl.uniprot.org/uniprot/E3LLW9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ROX family. NO66 subfamily.|||Binds 1 Fe(2+) ion per subunit.|||Nucleus|||Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. http://togogenome.org/gene/31234:GCK72_018176 ^@ http://purl.uniprot.org/uniprot/E3LPY0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel (TC 2.A.49) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_005561 ^@ http://purl.uniprot.org/uniprot/E3LFV9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/31234:GCK72_002148 ^@ http://purl.uniprot.org/uniprot/E3LLZ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_006642 ^@ http://purl.uniprot.org/uniprot/E3LRH5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat BOP1/ERB1 family.|||Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.|||nucleolus|||nucleoplasm http://togogenome.org/gene/31234:GCK72_016416 ^@ http://purl.uniprot.org/uniprot/E3MQT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_005281 ^@ http://purl.uniprot.org/uniprot/E3LF25 ^@ Function|||Similarity ^@ Belongs to the MGR2 family.|||Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.|||Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation. http://togogenome.org/gene/31234:GCK72_004795 ^@ http://purl.uniprot.org/uniprot/E3MZV6 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_006301 ^@ http://purl.uniprot.org/uniprot/E3LQZ7 ^@ Function|||Similarity ^@ Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.|||Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_018156 ^@ http://purl.uniprot.org/uniprot/E3LPW5 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/31234:GCK72_020420 ^@ http://purl.uniprot.org/uniprot/E3LIQ8 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. http://togogenome.org/gene/31234:GCK72_017939 ^@ http://purl.uniprot.org/uniprot/E3LUU4 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/31234:GCK72_023554 ^@ http://purl.uniprot.org/uniprot/E3M2R3 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/31234:GCK72_018319 ^@ http://purl.uniprot.org/uniprot/E3LNJ5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_022164 ^@ http://purl.uniprot.org/uniprot/E3MAB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/31234:GCK72_011631 ^@ http://purl.uniprot.org/uniprot/E3MNK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/31234:GCK72_006162 ^@ http://purl.uniprot.org/uniprot/E3LRD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_018523 ^@ http://purl.uniprot.org/uniprot/E3LP57 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017427 ^@ http://purl.uniprot.org/uniprot/E3MN82 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_011609 ^@ http://purl.uniprot.org/uniprot/E3MNN3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.|||Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS).|||Monomer. http://togogenome.org/gene/31234:GCK72_010066 ^@ http://purl.uniprot.org/uniprot/E3MCW4 ^@ Similarity ^@ Belongs to the mab-21 family. http://togogenome.org/gene/31234:GCK72_018421 ^@ http://purl.uniprot.org/uniprot/E3LNV3 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family. http://togogenome.org/gene/31234:GCK72_006363 ^@ http://purl.uniprot.org/uniprot/E3LQS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.|||Membrane|||Peroxisome membrane http://togogenome.org/gene/31234:GCK72_018013 ^@ http://purl.uniprot.org/uniprot/E3LPH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/31234:GCK72_023326 ^@ http://purl.uniprot.org/uniprot/E3MAZ3 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/31234:GCK72_018806 ^@ http://purl.uniprot.org/uniprot/E3LZP1 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/31234:GCK72_010198 ^@ http://purl.uniprot.org/uniprot/E3MI42 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/31234:GCK72_000718 ^@ http://purl.uniprot.org/uniprot/E3M3C2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endosulfine family.|||Cytoplasm|||Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. http://togogenome.org/gene/31234:GCK72_004548 ^@ http://purl.uniprot.org/uniprot/E3MS49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat DCAF13/WDSOF1 family.|||nucleolus http://togogenome.org/gene/31234:GCK72_022037 ^@ http://purl.uniprot.org/uniprot/E3NB62 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/31234:GCK72_005857 ^@ http://purl.uniprot.org/uniprot/E3M447 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_009121 ^@ http://purl.uniprot.org/uniprot/E3MKT9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_024449 ^@ http://purl.uniprot.org/uniprot/E3LDX4 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/31234:GCK72_011594 ^@ http://purl.uniprot.org/uniprot/E3MNP9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS8 family. http://togogenome.org/gene/31234:GCK72_010285 ^@ http://purl.uniprot.org/uniprot/E3MI67 ^@ Similarity ^@ Belongs to the DENR family. http://togogenome.org/gene/31234:GCK72_000439 ^@ http://purl.uniprot.org/uniprot/E3MWY7 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/31234:GCK72_004782 ^@ http://purl.uniprot.org/uniprot/E3MZW8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_003237 ^@ http://purl.uniprot.org/uniprot/E3N9X9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_018060 ^@ http://purl.uniprot.org/uniprot/E3LPL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_006372 ^@ http://purl.uniprot.org/uniprot/E3LQR7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acid sphingomyelinase family.|||Binds 2 Zn(2+) ions per subunit.|||Converts sphingomyelin to ceramide.|||Secreted http://togogenome.org/gene/31234:GCK72_012848 ^@ http://purl.uniprot.org/uniprot/E3NEN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecY/SEC61-alpha family.|||Membrane http://togogenome.org/gene/31234:GCK72_022858 ^@ http://purl.uniprot.org/uniprot/E3MLJ4 ^@ Similarity ^@ Belongs to the NAD kinase family. http://togogenome.org/gene/31234:GCK72_004349 ^@ http://purl.uniprot.org/uniprot/E3NIS9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_006522 ^@ http://purl.uniprot.org/uniprot/E3LQA3 ^@ Similarity ^@ Belongs to the alpha-carbonic anhydrase family. http://togogenome.org/gene/31234:GCK72_002474 ^@ http://purl.uniprot.org/uniprot/E3LVS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Membrane http://togogenome.org/gene/31234:GCK72_006391 ^@ http://purl.uniprot.org/uniprot/E3LQP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_024091 ^@ http://purl.uniprot.org/uniprot/E3LCE2 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/31234:GCK72_011883 ^@ http://purl.uniprot.org/uniprot/E3ML96 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/31234:GCK72_010816 ^@ http://purl.uniprot.org/uniprot/E3LWM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_002619 ^@ http://purl.uniprot.org/uniprot/E3LVC3 ^@ Similarity ^@ Belongs to the FAM76 family. http://togogenome.org/gene/31234:GCK72_004819 ^@ http://purl.uniprot.org/uniprot/E3MZT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS1/PSF1 family.|||Component of the GINS complex.|||Nucleus|||Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. http://togogenome.org/gene/31234:GCK72_009313 ^@ http://purl.uniprot.org/uniprot/E3N068 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/31234:GCK72_020866 ^@ http://purl.uniprot.org/uniprot/E3MBJ0 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_014616 ^@ http://purl.uniprot.org/uniprot/E3M601 ^@ Similarity ^@ Belongs to the WAPL family. http://togogenome.org/gene/31234:GCK72_005444 ^@ http://purl.uniprot.org/uniprot/Q4TTM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the F-actin-capping protein beta subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_015688 ^@ http://purl.uniprot.org/uniprot/E3N903 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Putative Notch ligand involved in the mediation of Notch signaling. http://togogenome.org/gene/31234:GCK72_026127 ^@ http://purl.uniprot.org/uniprot/E3MPK8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/31234:GCK72_017691 ^@ http://purl.uniprot.org/uniprot/E3LU34 ^@ Similarity|||Subunit ^@ Homotetramer.|||In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.|||In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. http://togogenome.org/gene/31234:GCK72_005676 ^@ http://purl.uniprot.org/uniprot/E3LG82 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/31234:GCK72_014150 ^@ http://purl.uniprot.org/uniprot/E3M7Z4 ^@ Similarity ^@ Belongs to the glycosyltransferase 47 family. http://togogenome.org/gene/31234:GCK72_006084 ^@ http://purl.uniprot.org/uniprot/E3M4S6 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_024691 ^@ http://purl.uniprot.org/uniprot/E3LD70 ^@ Function|||Similarity ^@ Belongs to the alpha-carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/31234:GCK72_015096 ^@ http://purl.uniprot.org/uniprot/E3M5W4 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_015181 ^@ http://purl.uniprot.org/uniprot/E3N2G7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the U1 small nuclear ribonucleoprotein C family.|||Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.|||Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.|||Nucleus|||U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA. http://togogenome.org/gene/31234:GCK72_015753 ^@ http://purl.uniprot.org/uniprot/E3NK68 ^@ Similarity ^@ Belongs to the tRNA-intron endonuclease family. http://togogenome.org/gene/31234:GCK72_001310 ^@ http://purl.uniprot.org/uniprot/E3LXC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_019907 ^@ http://purl.uniprot.org/uniprot/E3LJG3 ^@ Similarity ^@ Belongs to the FAX family. http://togogenome.org/gene/31234:GCK72_010848 ^@ http://purl.uniprot.org/uniprot/E3LWJ1 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_017208 ^@ http://purl.uniprot.org/uniprot/E3N522 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_001295 ^@ http://purl.uniprot.org/uniprot/E3LXE2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase G subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/31234:GCK72_011581 ^@ http://purl.uniprot.org/uniprot/E3MNQ8 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/31234:GCK72_005323 ^@ http://purl.uniprot.org/uniprot/E3LF70|||http://purl.uniprot.org/uniprot/I6NEP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 8 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_014640 ^@ http://purl.uniprot.org/uniprot/E3M702 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COG8 family.|||Membrane http://togogenome.org/gene/31234:GCK72_007925 ^@ http://purl.uniprot.org/uniprot/E3NII5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/31234:GCK72_020014 ^@ http://purl.uniprot.org/uniprot/E3LHE7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_010867 ^@ http://purl.uniprot.org/uniprot/E3LWG7 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_005791 ^@ http://purl.uniprot.org/uniprot/E3MMT0 ^@ Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. http://togogenome.org/gene/31234:GCK72_019104 ^@ http://purl.uniprot.org/uniprot/E3LKM6 ^@ Similarity ^@ Belongs to the RNase T2 family. http://togogenome.org/gene/31234:GCK72_025525 ^@ http://purl.uniprot.org/uniprot/E3MCG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005151 ^@ http://purl.uniprot.org/uniprot/E3LH00 ^@ Function|||Similarity ^@ Belongs to the MnmG family.|||Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. http://togogenome.org/gene/31234:GCK72_025607 ^@ http://purl.uniprot.org/uniprot/E3MC87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMDT1/EMRE family.|||Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.|||Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_006169 ^@ http://purl.uniprot.org/uniprot/E3LRD1 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/31234:GCK72_003823 ^@ http://purl.uniprot.org/uniprot/E3MXG5 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/31234:GCK72_010630 ^@ http://purl.uniprot.org/uniprot/E3LYV0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_014476 ^@ http://purl.uniprot.org/uniprot/E3M6F6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_017892 ^@ http://purl.uniprot.org/uniprot/E3LUP4 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_008834 ^@ http://purl.uniprot.org/uniprot/E3M8F3 ^@ Similarity ^@ Belongs to the RRN3 family. http://togogenome.org/gene/31234:GCK72_004031 ^@ http://purl.uniprot.org/uniprot/E3MQN8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the kinesin light chain family.|||Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.|||Oligomeric complex composed of two heavy chains and two light chains.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_017975 ^@ http://purl.uniprot.org/uniprot/E3LTF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_014366 ^@ http://purl.uniprot.org/uniprot/E3MM37 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily. http://togogenome.org/gene/31234:GCK72_013359 ^@ http://purl.uniprot.org/uniprot/E3NHI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Membrane http://togogenome.org/gene/31234:GCK72_013543 ^@ http://purl.uniprot.org/uniprot/E3MR30 ^@ Similarity ^@ Belongs to the histone deacetylase family. HD type 2 subfamily. http://togogenome.org/gene/31234:GCK72_009490 ^@ http://purl.uniprot.org/uniprot/E3LS99 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/31234:GCK72_004276 ^@ http://purl.uniprot.org/uniprot/E3NI84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/31234:GCK72_014491 ^@ http://purl.uniprot.org/uniprot/E3M6D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/31234:GCK72_002457 ^@ http://purl.uniprot.org/uniprot/E3LVU3 ^@ Function|||Similarity ^@ Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).|||Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily. http://togogenome.org/gene/31234:GCK72_001793 ^@ http://purl.uniprot.org/uniprot/E3LLP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_025401 ^@ http://purl.uniprot.org/uniprot/E3MJN1 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_018404 ^@ http://purl.uniprot.org/uniprot/E3LNT0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_011473 ^@ http://purl.uniprot.org/uniprot/E3ND59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/31234:GCK72_015777 ^@ http://purl.uniprot.org/uniprot/E3NGT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL46 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_001494 ^@ http://purl.uniprot.org/uniprot/E3N1P2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_025171 ^@ http://purl.uniprot.org/uniprot/E3MZB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NFYA/HAP2 subunit family.|||Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.|||Heterotrimer.|||Nucleus http://togogenome.org/gene/31234:GCK72_002697 ^@ http://purl.uniprot.org/uniprot/E3LV28 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/31234:GCK72_002444 ^@ http://purl.uniprot.org/uniprot/E3LVV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TM2 family.|||Membrane http://togogenome.org/gene/31234:GCK72_025780 ^@ http://purl.uniprot.org/uniprot/E3ME48 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_025833 ^@ http://purl.uniprot.org/uniprot/E3MEA4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_016742 ^@ http://purl.uniprot.org/uniprot/E3MQB7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_019389 ^@ http://purl.uniprot.org/uniprot/E3LKE1 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_000031 ^@ http://purl.uniprot.org/uniprot/E3MT61 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane http://togogenome.org/gene/31234:GCK72_010036 ^@ http://purl.uniprot.org/uniprot/E3MCS9 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_014585 ^@ http://purl.uniprot.org/uniprot/E3M639 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_023325 ^@ http://purl.uniprot.org/uniprot/E3MAZ2 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/31234:GCK72_000614 ^@ http://purl.uniprot.org/uniprot/E3M315 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B family. http://togogenome.org/gene/31234:GCK72_010433 ^@ http://purl.uniprot.org/uniprot/E3LZF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SWEET sugar transporter family.|||Cell membrane|||Golgi apparatus membrane|||Mediates sugar transport across membranes.|||Membrane http://togogenome.org/gene/31234:GCK72_018666 ^@ http://purl.uniprot.org/uniprot/E3M0G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_019221 ^@ http://purl.uniprot.org/uniprot/E3LLD1 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/31234:GCK72_020161 ^@ http://purl.uniprot.org/uniprot/E3LHV2 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/31234:GCK72_002975 ^@ http://purl.uniprot.org/uniprot/E3N7I6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat LST8 family.|||Cytoplasm|||Part of TORC1 complex. Part of the TORC2 complex.|||Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. http://togogenome.org/gene/31234:GCK72_017111 ^@ http://purl.uniprot.org/uniprot/E3NCZ3 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_013938 ^@ http://purl.uniprot.org/uniprot/E3M7B9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter. http://togogenome.org/gene/31234:GCK72_018032 ^@ http://purl.uniprot.org/uniprot/E3LPJ1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_001695 ^@ http://purl.uniprot.org/uniprot/E3LN66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL52 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_017973 ^@ http://purl.uniprot.org/uniprot/E3LTF8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_019980 ^@ http://purl.uniprot.org/uniprot/E3LHA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_019663 ^@ http://purl.uniprot.org/uniprot/E3N7G4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_020053 ^@ http://purl.uniprot.org/uniprot/E3LHJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Component of the large ribosomal subunit.|||Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.|||Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_002257 ^@ http://purl.uniprot.org/uniprot/E3MGH2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family. http://togogenome.org/gene/31234:GCK72_012879 ^@ http://purl.uniprot.org/uniprot/E3NC55 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/31234:GCK72_024640 ^@ http://purl.uniprot.org/uniprot/E3LDC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/31234:GCK72_024267 ^@ http://purl.uniprot.org/uniprot/E3LEG6 ^@ Similarity ^@ Belongs to the patched family. http://togogenome.org/gene/31234:GCK72_002104 ^@ http://purl.uniprot.org/uniprot/E3LM32 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/31234:GCK72_016919 ^@ http://purl.uniprot.org/uniprot/E3MHJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_014565 ^@ http://purl.uniprot.org/uniprot/E3M660 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. DCP2 subfamily. http://togogenome.org/gene/31234:GCK72_006965 ^@ http://purl.uniprot.org/uniprot/E3M1J9 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_004886 ^@ http://purl.uniprot.org/uniprot/E3LG96 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/31234:GCK72_009990 ^@ http://purl.uniprot.org/uniprot/E3MCM7 ^@ Subcellular Location Annotation ^@ Nucleus|||kinetochore http://togogenome.org/gene/31234:GCK72_018208 ^@ http://purl.uniprot.org/uniprot/E3LQ11 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_005626 ^@ http://purl.uniprot.org/uniprot/E3LG26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_017521 ^@ http://purl.uniprot.org/uniprot/E3LTK8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_019940 ^@ http://purl.uniprot.org/uniprot/E3LJK6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_004520 ^@ http://purl.uniprot.org/uniprot/E3MS24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_011772 ^@ http://purl.uniprot.org/uniprot/E3MSK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_010884 ^@ http://purl.uniprot.org/uniprot/E3LWE4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ARPC3 family.|||Component of the Arp2/3 complex.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_000251 ^@ http://purl.uniprot.org/uniprot/E3NBV5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFS6 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_001974 ^@ http://purl.uniprot.org/uniprot/E3LMH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_011982 ^@ http://purl.uniprot.org/uniprot/E3MK75 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_011896 ^@ http://purl.uniprot.org/uniprot/E3MLB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_024041 ^@ http://purl.uniprot.org/uniprot/E3LCN9 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_015169 ^@ http://purl.uniprot.org/uniprot/E3NAH9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_017414 ^@ http://purl.uniprot.org/uniprot/E3MN67 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10A family.|||Binds 2 Zn(2+) ions per subunit.|||Can bind about 5 Ca(2+) ions per subunit. http://togogenome.org/gene/31234:GCK72_021981 ^@ http://purl.uniprot.org/uniprot/E3MEW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-CoA oxidase family.|||Peroxisome http://togogenome.org/gene/31234:GCK72_005294 ^@ http://purl.uniprot.org/uniprot/E3LF41 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RAD23 family.|||Cytoplasm|||Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.|||Nucleus http://togogenome.org/gene/31234:GCK72_017258 ^@ http://purl.uniprot.org/uniprot/E3N1X2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_010276 ^@ http://purl.uniprot.org/uniprot/E3MIH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/31234:GCK72_024505 ^@ http://purl.uniprot.org/uniprot/E3LDR5 ^@ Similarity ^@ Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. http://togogenome.org/gene/31234:GCK72_002439 ^@ http://purl.uniprot.org/uniprot/E3LVW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit E family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_003726 ^@ http://purl.uniprot.org/uniprot/E3N2S5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_013402 ^@ http://purl.uniprot.org/uniprot/E3N5Q3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase e1/e2 subunit family.|||Membrane|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/31234:GCK72_005377 ^@ http://purl.uniprot.org/uniprot/E3LFC2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Tim17/Tim22/Tim23 family.|||Component of the TIM22 complex.|||Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_021984 ^@ http://purl.uniprot.org/uniprot/E3MEW3 ^@ Similarity ^@ Belongs to the cuticular collagen family. http://togogenome.org/gene/31234:GCK72_006509 ^@ http://purl.uniprot.org/uniprot/E3LQC0 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_000993 ^@ http://purl.uniprot.org/uniprot/E3LYA3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010658 ^@ http://purl.uniprot.org/uniprot/E3LYR7 ^@ Similarity ^@ Belongs to the requiem/DPF family. http://togogenome.org/gene/31234:GCK72_014241 ^@ http://purl.uniprot.org/uniprot/E3N328 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_016336 ^@ http://purl.uniprot.org/uniprot/E3N5V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ARMET family.|||Secreted http://togogenome.org/gene/31234:GCK72_017981 ^@ http://purl.uniprot.org/uniprot/E3LTG4 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/31234:GCK72_020310 ^@ http://purl.uniprot.org/uniprot/E3LID3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_019994 ^@ http://purl.uniprot.org/uniprot/E3LHC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_014637 ^@ http://purl.uniprot.org/uniprot/E3M705 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TFB1 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_012001 ^@ http://purl.uniprot.org/uniprot/E3MK55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_020079 ^@ http://purl.uniprot.org/uniprot/E3LHL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_008790 ^@ http://purl.uniprot.org/uniprot/E3M8I8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_024954 ^@ http://purl.uniprot.org/uniprot/E3MVN2 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/31234:GCK72_012140 ^@ http://purl.uniprot.org/uniprot/E3MEM2 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family. http://togogenome.org/gene/31234:GCK72_018296 ^@ http://purl.uniprot.org/uniprot/E3LNH1 ^@ Similarity ^@ Belongs to the FAX family. http://togogenome.org/gene/31234:GCK72_015844 ^@ http://purl.uniprot.org/uniprot/E3NKT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_004931 ^@ http://purl.uniprot.org/uniprot/E3LGE4 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/31234:GCK72_001245 ^@ http://purl.uniprot.org/uniprot/E3LXJ8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/31234:GCK72_009638 ^@ http://purl.uniprot.org/uniprot/E3LRU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PHAX family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_024343 ^@ http://purl.uniprot.org/uniprot/E3LE89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_019556 ^@ http://purl.uniprot.org/uniprot/E3LLE5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_009868 ^@ http://purl.uniprot.org/uniprot/E3LST6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_000783 ^@ http://purl.uniprot.org/uniprot/E3M3H2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/31234:GCK72_018219 ^@ http://purl.uniprot.org/uniprot/E3LQ22 ^@ Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family. http://togogenome.org/gene/31234:GCK72_006395 ^@ http://purl.uniprot.org/uniprot/E3LQP4 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/31234:GCK72_024509 ^@ http://purl.uniprot.org/uniprot/E3LDR1 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/31234:GCK72_001232 ^@ http://purl.uniprot.org/uniprot/E3LXL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Late endosome membrane|||Membrane http://togogenome.org/gene/31234:GCK72_011061 ^@ http://purl.uniprot.org/uniprot/E3NGC0 ^@ Similarity ^@ Belongs to the Luc7 family. http://togogenome.org/gene/31234:GCK72_010585 ^@ http://purl.uniprot.org/uniprot/E3LYZ4 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_013862 ^@ http://purl.uniprot.org/uniprot/E3NW46 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_010408 ^@ http://purl.uniprot.org/uniprot/E3LZH4 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruB family. http://togogenome.org/gene/31234:GCK72_006492 ^@ http://purl.uniprot.org/uniprot/E3LQD4 ^@ Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family. http://togogenome.org/gene/31234:GCK72_005152 ^@ http://purl.uniprot.org/uniprot/E3LH01 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/31234:GCK72_009388 ^@ http://purl.uniprot.org/uniprot/E3LSK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/31234:GCK72_005584 ^@ http://purl.uniprot.org/uniprot/E3LFY3 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_024404 ^@ http://purl.uniprot.org/uniprot/E3LE28 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/31234:GCK72_011999 ^@ http://purl.uniprot.org/uniprot/E3MK57 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/31234:GCK72_013075 ^@ http://purl.uniprot.org/uniprot/E3NKZ9 ^@ Similarity ^@ Belongs to the selenium-binding protein family. http://togogenome.org/gene/31234:GCK72_002236 ^@ http://purl.uniprot.org/uniprot/E3MGE9 ^@ Similarity ^@ Belongs to the NKAP family. http://togogenome.org/gene/31234:GCK72_010333 ^@ http://purl.uniprot.org/uniprot/E3LYL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_024580 ^@ http://purl.uniprot.org/uniprot/E3LDI9 ^@ Similarity ^@ Belongs to the troponin T family. http://togogenome.org/gene/31234:GCK72_011004 ^@ http://purl.uniprot.org/uniprot/E3LX51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/31234:GCK72_014605 ^@ http://purl.uniprot.org/uniprot/E3M613 ^@ Similarity ^@ Belongs to the glycine N-acyltransferase family. http://togogenome.org/gene/31234:GCK72_015993 ^@ http://purl.uniprot.org/uniprot/E3N974 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_002009 ^@ http://purl.uniprot.org/uniprot/E3LMD6 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/31234:GCK72_004871 ^@ http://purl.uniprot.org/uniprot/E3NIU0 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/31234:GCK72_014998 ^@ http://purl.uniprot.org/uniprot/E3M5K8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_004848 ^@ http://purl.uniprot.org/uniprot/E3NHD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat PLAP family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_019196 ^@ http://purl.uniprot.org/uniprot/E3LL81 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srg family. http://togogenome.org/gene/31234:GCK72_010457 ^@ http://purl.uniprot.org/uniprot/E3LZD1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.|||Belongs to the URM1 family.|||C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of the MOCS3/UBA4 homolog, then thiocarboxylated (-COSH) via the rhodanese domain of the MOCS3/UBA4 homolog.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_019527 ^@ http://purl.uniprot.org/uniprot/E3LL65 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_017091 ^@ http://purl.uniprot.org/uniprot/E3NLG7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/31234:GCK72_004301 ^@ http://purl.uniprot.org/uniprot/E3NE72 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase F subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/31234:GCK72_001291 ^@ http://purl.uniprot.org/uniprot/E3LXE7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.|||Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_005876 ^@ http://purl.uniprot.org/uniprot/E3M465 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_005955 ^@ http://purl.uniprot.org/uniprot/E3M4F1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_009988 ^@ http://purl.uniprot.org/uniprot/E3MCM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S54 family.|||Membrane http://togogenome.org/gene/31234:GCK72_005595 ^@ http://purl.uniprot.org/uniprot/E3LFZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sarcoglycan beta/delta/gamma/zeta family.|||cytoskeleton|||sarcolemma http://togogenome.org/gene/31234:GCK72_006593 ^@ http://purl.uniprot.org/uniprot/E3LRM7 ^@ Similarity|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Homodimer. http://togogenome.org/gene/31234:GCK72_005771 ^@ http://purl.uniprot.org/uniprot/E3MMV1 ^@ Similarity ^@ Belongs to the WASH1 family. http://togogenome.org/gene/31234:GCK72_024345 ^@ http://purl.uniprot.org/uniprot/E3LE87 ^@ Similarity ^@ Belongs to the 3-beta-HSD family. http://togogenome.org/gene/31234:GCK72_014510 ^@ http://purl.uniprot.org/uniprot/E3M6C0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/31234:GCK72_008516 ^@ http://purl.uniprot.org/uniprot/E3NHE7 ^@ Function|||Similarity ^@ Belongs to the NARF family.|||Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. http://togogenome.org/gene/31234:GCK72_006494 ^@ http://purl.uniprot.org/uniprot/E3LQD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_000050 ^@ http://purl.uniprot.org/uniprot/E3MT42 ^@ Function ^@ May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells. http://togogenome.org/gene/31234:GCK72_011059 ^@ http://purl.uniprot.org/uniprot/E3NGB8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DSS1/SEM1 family.|||Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.|||Nucleus http://togogenome.org/gene/31234:GCK72_018824 ^@ http://purl.uniprot.org/uniprot/E3LZQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MPDU1 (TC 2.A.43.3) family.|||Membrane http://togogenome.org/gene/31234:GCK72_004213 ^@ http://purl.uniprot.org/uniprot/E3MPY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_010691 ^@ http://purl.uniprot.org/uniprot/E3NH10 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_011783 ^@ http://purl.uniprot.org/uniprot/E3MSL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-binding oxidoreductase/transferase type 4 family.|||Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.|||Homodimer.|||Peroxisome http://togogenome.org/gene/31234:GCK72_006460 ^@ http://purl.uniprot.org/uniprot/E3LQH0 ^@ Similarity ^@ Belongs to the peroxin-13 family. http://togogenome.org/gene/31234:GCK72_013401 ^@ http://purl.uniprot.org/uniprot/E3N5Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase K family.|||Membrane http://togogenome.org/gene/31234:GCK72_009648 ^@ http://purl.uniprot.org/uniprot/E3LRT9 ^@ Similarity ^@ Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family. http://togogenome.org/gene/31234:GCK72_025338 ^@ http://purl.uniprot.org/uniprot/E3MU78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 27 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_021589 ^@ http://purl.uniprot.org/uniprot/E3NDM7 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/31234:GCK72_000036 ^@ http://purl.uniprot.org/uniprot/E3MT55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TLS1 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_023355 ^@ http://purl.uniprot.org/uniprot/E3MB24 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/31234:GCK72_013948 ^@ http://purl.uniprot.org/uniprot/E3M798 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_008368 ^@ http://purl.uniprot.org/uniprot/E3MFQ3 ^@ Similarity ^@ Belongs to the NC2 beta/DR1 family. http://togogenome.org/gene/31234:GCK72_022251 ^@ http://purl.uniprot.org/uniprot/E3MA19 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_014618 ^@ http://purl.uniprot.org/uniprot/E3M600 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_008242 ^@ http://purl.uniprot.org/uniprot/E3MP23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS3 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_017478 ^@ http://purl.uniprot.org/uniprot/E3MNE1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20A family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/31234:GCK72_005806 ^@ http://purl.uniprot.org/uniprot/E3MMR3 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/31234:GCK72_003859 ^@ http://purl.uniprot.org/uniprot/E3NJA0 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_009098 ^@ http://purl.uniprot.org/uniprot/E3NI46 ^@ Similarity ^@ Belongs to the FAH family. http://togogenome.org/gene/31234:GCK72_010047 ^@ http://purl.uniprot.org/uniprot/E3MCU1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/31234:GCK72_010951 ^@ http://purl.uniprot.org/uniprot/E3LW78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FRG1 family.|||Cajal body|||nucleolus http://togogenome.org/gene/31234:GCK72_016406 ^@ http://purl.uniprot.org/uniprot/E3MQS1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the poly(A) polymerase family.|||Binds 2 magnesium ions. Also active with manganese.|||Nucleus|||Polymerase that creates the 3'-poly(A) tail of mRNA's. http://togogenome.org/gene/31234:GCK72_008806 ^@ http://purl.uniprot.org/uniprot/E3M8H2 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/31234:GCK72_010487 ^@ http://purl.uniprot.org/uniprot/E3LZA2 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_002892 ^@ http://purl.uniprot.org/uniprot/E3MXM9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_010261 ^@ http://purl.uniprot.org/uniprot/E3MIF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP25 family.|||nucleolus http://togogenome.org/gene/31234:GCK72_000576 ^@ http://purl.uniprot.org/uniprot/E3M3V3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL14 family. http://togogenome.org/gene/31234:GCK72_022489 ^@ http://purl.uniprot.org/uniprot/E3N500 ^@ Similarity ^@ Belongs to the argonaute family. http://togogenome.org/gene/31234:GCK72_003607 ^@ http://purl.uniprot.org/uniprot/E3M911 ^@ Similarity ^@ Belongs to the GPI family. http://togogenome.org/gene/31234:GCK72_004560 ^@ http://purl.uniprot.org/uniprot/E3MHX2 ^@ Similarity ^@ Belongs to the CNOT2/3/5 family. http://togogenome.org/gene/31234:GCK72_002391 ^@ http://purl.uniprot.org/uniprot/E3LW09 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/31234:GCK72_006099 ^@ http://purl.uniprot.org/uniprot/E3M4U0 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/31234:GCK72_013680 ^@ http://purl.uniprot.org/uniprot/E3MS90 ^@ Similarity ^@ Belongs to the MIF family. http://togogenome.org/gene/31234:GCK72_009472 ^@ http://purl.uniprot.org/uniprot/E3LSB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S54 family.|||Membrane http://togogenome.org/gene/31234:GCK72_019197 ^@ http://purl.uniprot.org/uniprot/E3LL82 ^@ Caution|||Similarity ^@ Belongs to the nematode receptor-like protein srg family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_002518 ^@ http://purl.uniprot.org/uniprot/E3LVM8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS19 family. http://togogenome.org/gene/31234:GCK72_006228 ^@ http://purl.uniprot.org/uniprot/E3LR76 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017402 ^@ http://purl.uniprot.org/uniprot/E3MN52 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ENY2 family.|||Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).|||Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.|||nucleoplasm http://togogenome.org/gene/31234:GCK72_017829 ^@ http://purl.uniprot.org/uniprot/E3LUI0 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_011686 ^@ http://purl.uniprot.org/uniprot/E3NAJ6 ^@ Similarity ^@ Belongs to the AP-2 family. http://togogenome.org/gene/31234:GCK72_016625 ^@ http://purl.uniprot.org/uniprot/E3MTQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_001458 ^@ http://purl.uniprot.org/uniprot/E3MFC6 ^@ Caution|||Similarity ^@ Belongs to the cuticular collagen family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_018316 ^@ http://purl.uniprot.org/uniprot/E3LNJ1 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_005795 ^@ http://purl.uniprot.org/uniprot/E3MMS4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family. http://togogenome.org/gene/31234:GCK72_024657 ^@ http://purl.uniprot.org/uniprot/E3LDA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_010851 ^@ http://purl.uniprot.org/uniprot/E3LWI6 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_015132 ^@ http://purl.uniprot.org/uniprot/E3NAE8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_002065 ^@ http://purl.uniprot.org/uniprot/E3LM77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.|||Nucleus http://togogenome.org/gene/31234:GCK72_014727 ^@ http://purl.uniprot.org/uniprot/E3M6R1 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/31234:GCK72_010881 ^@ http://purl.uniprot.org/uniprot/E3LWE8 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_005360 ^@ http://purl.uniprot.org/uniprot/E3LFA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel (TC 2.A.49) family.|||Membrane http://togogenome.org/gene/31234:GCK72_025402 ^@ http://purl.uniprot.org/uniprot/E3MJN0 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_017983 ^@ http://purl.uniprot.org/uniprot/E3LTG6 ^@ Caution|||Similarity ^@ Belongs to the nematode receptor-like protein srg family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_009071 ^@ http://purl.uniprot.org/uniprot/E3NFB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_022255 ^@ http://purl.uniprot.org/uniprot/E3MA17 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/31234:GCK72_001996 ^@ http://purl.uniprot.org/uniprot/E3LMF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_000968 ^@ http://purl.uniprot.org/uniprot/E3LYD3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017221 ^@ http://purl.uniprot.org/uniprot/E3NP53 ^@ Similarity ^@ Belongs to the UPF0046 family. http://togogenome.org/gene/31234:GCK72_001986 ^@ http://purl.uniprot.org/uniprot/E3LMG6 ^@ Caution|||Similarity ^@ Belongs to the peptidase C2 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_008940 ^@ http://purl.uniprot.org/uniprot/E3MWJ3 ^@ Similarity ^@ Belongs to the NSRP1 family. http://togogenome.org/gene/31234:GCK72_024558 ^@ http://purl.uniprot.org/uniprot/E3LDL0 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_010003 ^@ http://purl.uniprot.org/uniprot/E3MCP1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family. http://togogenome.org/gene/31234:GCK72_005844 ^@ http://purl.uniprot.org/uniprot/E3M433 ^@ Similarity ^@ Belongs to the JHDM3 histone demethylase family. http://togogenome.org/gene/31234:GCK72_010638 ^@ http://purl.uniprot.org/uniprot/E3LYU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_008325 ^@ http://purl.uniprot.org/uniprot/E3MFV2 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/31234:GCK72_000443 ^@ http://purl.uniprot.org/uniprot/E3MWZ1 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 2 family. http://togogenome.org/gene/31234:GCK72_001789 ^@ http://purl.uniprot.org/uniprot/E3LLP5 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/31234:GCK72_020406 ^@ http://purl.uniprot.org/uniprot/E3LIP2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YIF1 family.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Has a role in transport between endoplasmic reticulum and Golgi.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_024273 ^@ http://purl.uniprot.org/uniprot/E3LEG0 ^@ Similarity ^@ Belongs to the TOM1 family. http://togogenome.org/gene/31234:GCK72_011967 ^@ http://purl.uniprot.org/uniprot/E3MK89 ^@ Function|||Similarity ^@ Belongs to the UFL1 family.|||E3 UFM1-protein ligase that mediates ufmylation of target proteins. http://togogenome.org/gene/31234:GCK72_005178 ^@ http://purl.uniprot.org/uniprot/E3LH27 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic GSH synthase family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/31234:GCK72_024336 ^@ http://purl.uniprot.org/uniprot/E3LE97 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_020575 ^@ http://purl.uniprot.org/uniprot/E3MWQ0 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_016680 ^@ http://purl.uniprot.org/uniprot/E3NF70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the battenin family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/31234:GCK72_010728 ^@ http://purl.uniprot.org/uniprot/E3LWW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NFX1 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_003693 ^@ http://purl.uniprot.org/uniprot/E3N2W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/31234:GCK72_019898 ^@ http://purl.uniprot.org/uniprot/E3LJF4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_018768 ^@ http://purl.uniprot.org/uniprot/E3LZK1 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/31234:GCK72_013550 ^@ http://purl.uniprot.org/uniprot/E3MR23 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC4 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_003062 ^@ http://purl.uniprot.org/uniprot/E3N005 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZWILCH family.|||Component of the RZZ complex.|||Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for chromosome segregation, the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores and spindle pole separation. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex.|||kinetochore http://togogenome.org/gene/31234:GCK72_000461 ^@ http://purl.uniprot.org/uniprot/E3MX08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/31234:GCK72_005708 ^@ http://purl.uniprot.org/uniprot/E3MN24 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_024917 ^@ http://purl.uniprot.org/uniprot/E3MVJ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Tango11 family.|||Mitochondrion outer membrane|||Peroxisome|||Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. http://togogenome.org/gene/31234:GCK72_014981 ^@ http://purl.uniprot.org/uniprot/E3M5I8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the insulin family.|||Heterodimer of a B chain and an A chain linked by two disulfide bonds.|||Secreted http://togogenome.org/gene/31234:GCK72_025666 ^@ http://purl.uniprot.org/uniprot/E3MC24 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. http://togogenome.org/gene/31234:GCK72_010764 ^@ http://purl.uniprot.org/uniprot/E3LWT1 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srg family. http://togogenome.org/gene/31234:GCK72_006596 ^@ http://purl.uniprot.org/uniprot/E3LRM4 ^@ Similarity ^@ Belongs to the REXO4 family. http://togogenome.org/gene/31234:GCK72_010270 ^@ http://purl.uniprot.org/uniprot/E3MIG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad1 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_021614 ^@ http://purl.uniprot.org/uniprot/E3N0I5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_008039 ^@ http://purl.uniprot.org/uniprot/E3MDR8 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/31234:GCK72_013466 ^@ http://purl.uniprot.org/uniprot/E3NDA2 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_013037 ^@ http://purl.uniprot.org/uniprot/E3NJR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001942 ^@ http://purl.uniprot.org/uniprot/E3LML2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/31234:GCK72_003656 ^@ http://purl.uniprot.org/uniprot/E3NB23 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_015019 ^@ http://purl.uniprot.org/uniprot/E3M5M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF2 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_021752 ^@ http://purl.uniprot.org/uniprot/E3N6I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_008251 ^@ http://purl.uniprot.org/uniprot/E3MG31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS3 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_018652 ^@ http://purl.uniprot.org/uniprot/E3M0E7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_018744 ^@ http://purl.uniprot.org/uniprot/E3M0Q3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_005075 ^@ http://purl.uniprot.org/uniprot/E3LGS9 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/31234:GCK72_001347 ^@ http://purl.uniprot.org/uniprot/E3LX92 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MICOS complex subunit Mic13 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_006591 ^@ http://purl.uniprot.org/uniprot/E3LRM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAD kinase family.|||Homodimer.|||Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_006175 ^@ http://purl.uniprot.org/uniprot/E3LRC5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_024521 ^@ http://purl.uniprot.org/uniprot/E3LDQ1 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Interacts with PEX19.|||Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.|||Peroxisome membrane http://togogenome.org/gene/31234:GCK72_014163 ^@ http://purl.uniprot.org/uniprot/E3NRQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_018118 ^@ http://purl.uniprot.org/uniprot/E3LPS5 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_008808 ^@ http://purl.uniprot.org/uniprot/E3M8H0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/31234:GCK72_011612 ^@ http://purl.uniprot.org/uniprot/E3MNM4 ^@ Function|||Similarity ^@ Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.|||Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_025002 ^@ http://purl.uniprot.org/uniprot/E3MRQ2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Microsome membrane http://togogenome.org/gene/31234:GCK72_024971 ^@ http://purl.uniprot.org/uniprot/E3MVP7 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_008108 ^@ http://purl.uniprot.org/uniprot/E3MDJ2 ^@ Similarity ^@ Belongs to the AP-2 family. http://togogenome.org/gene/31234:GCK72_021636 ^@ http://purl.uniprot.org/uniprot/E3N0G3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_024283 ^@ http://purl.uniprot.org/uniprot/E3LEF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_009353 ^@ http://purl.uniprot.org/uniprot/E3LSN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDK/BCKDK protein kinase family.|||Mitochondrion matrix http://togogenome.org/gene/31234:GCK72_010278 ^@ http://purl.uniprot.org/uniprot/E3MI61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ARTD/PARP family.|||Nucleus http://togogenome.org/gene/31234:GCK72_009123 ^@ http://purl.uniprot.org/uniprot/E3MKU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OST3/OST6 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_013817 ^@ http://purl.uniprot.org/uniprot/E3NE99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_021618 ^@ http://purl.uniprot.org/uniprot/E3N0I0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_004624 ^@ http://purl.uniprot.org/uniprot/E3MHT3 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL37 family.|||Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. http://togogenome.org/gene/31234:GCK72_014663 ^@ http://purl.uniprot.org/uniprot/E3M6X8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. http://togogenome.org/gene/31234:GCK72_021928 ^@ http://purl.uniprot.org/uniprot/E3MF17 ^@ Similarity ^@ Belongs to the FAM151 family. http://togogenome.org/gene/31234:GCK72_001492 ^@ http://purl.uniprot.org/uniprot/E3N1P4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/31234:GCK72_024350 ^@ http://purl.uniprot.org/uniprot/E3LE83 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_003497 ^@ http://purl.uniprot.org/uniprot/E3M8Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM242 family.|||Membrane http://togogenome.org/gene/31234:GCK72_014247 ^@ http://purl.uniprot.org/uniprot/E3MSX9 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/31234:GCK72_024452 ^@ http://purl.uniprot.org/uniprot/E3LDX2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_016921 ^@ http://purl.uniprot.org/uniprot/E3MHJ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005845 ^@ http://purl.uniprot.org/uniprot/E3M434 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/31234:GCK72_025226 ^@ http://purl.uniprot.org/uniprot/E3NDX9 ^@ Function|||Similarity ^@ Belongs to the SEC15 family.|||Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. http://togogenome.org/gene/31234:GCK72_015805 ^@ http://purl.uniprot.org/uniprot/E3N5J0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_002576 ^@ http://purl.uniprot.org/uniprot/E3LVG6 ^@ Similarity ^@ Belongs to the argonaute family. http://togogenome.org/gene/31234:GCK72_001249 ^@ http://purl.uniprot.org/uniprot/E3LXJ4 ^@ Function|||Similarity ^@ Belongs to the EAF family.|||Promotes transcriptional elongation by Su(Tpl)/ELL. Essential for development. http://togogenome.org/gene/31234:GCK72_016856 ^@ http://purl.uniprot.org/uniprot/E3NAZ0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family. http://togogenome.org/gene/31234:GCK72_007173 ^@ http://purl.uniprot.org/uniprot/E3MJ38 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_022256 ^@ http://purl.uniprot.org/uniprot/E3MA16 ^@ Subcellular Location Annotation ^@ cilium basal body http://togogenome.org/gene/31234:GCK72_018297 ^@ http://purl.uniprot.org/uniprot/E3LNH2 ^@ Similarity ^@ Belongs to the FAX family. http://togogenome.org/gene/31234:GCK72_022218 ^@ http://purl.uniprot.org/uniprot/E3MA55 ^@ Cofactor|||Similarity ^@ Belongs to the cysteine dioxygenase family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/31234:GCK72_008112 ^@ http://purl.uniprot.org/uniprot/E3MDI8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_018430 ^@ http://purl.uniprot.org/uniprot/E3LNW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_021619 ^@ http://purl.uniprot.org/uniprot/E3N0H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_006348 ^@ http://purl.uniprot.org/uniprot/E3LQU7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_009783 ^@ http://purl.uniprot.org/uniprot/E3LT17 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_016522 ^@ http://purl.uniprot.org/uniprot/E3N771 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/31234:GCK72_014285 ^@ http://purl.uniprot.org/uniprot/E3NPN7 ^@ Similarity ^@ Belongs to the UFD1 family. http://togogenome.org/gene/31234:GCK72_001017 ^@ http://purl.uniprot.org/uniprot/E3LY78 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/31234:GCK72_017509 ^@ http://purl.uniprot.org/uniprot/E3LTJ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRS1 family.|||Involved in ribosomal large subunit assembly.|||Nucleus http://togogenome.org/gene/31234:GCK72_024849 ^@ http://purl.uniprot.org/uniprot/E3LCI4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_025486 ^@ http://purl.uniprot.org/uniprot/E3MJE7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class II subfamily.|||Binds 1 zinc ion per subunit.|||Mitochondrion matrix|||NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues. http://togogenome.org/gene/31234:GCK72_011515 ^@ http://purl.uniprot.org/uniprot/E3MIK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_003513 ^@ http://purl.uniprot.org/uniprot/E3M8S3 ^@ Function|||Similarity ^@ Belongs to the phospholipid scramblase family.|||May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. http://togogenome.org/gene/31234:GCK72_019385 ^@ http://purl.uniprot.org/uniprot/E3LKD6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_019597 ^@ http://purl.uniprot.org/uniprot/E3LJN2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_000404 ^@ http://purl.uniprot.org/uniprot/E3N7R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_018025 ^@ http://purl.uniprot.org/uniprot/E3LPI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_016427 ^@ http://purl.uniprot.org/uniprot/E3MQU1 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/31234:GCK72_012847 ^@ http://purl.uniprot.org/uniprot/E3NEP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecY/SEC61-alpha family.|||Membrane http://togogenome.org/gene/31234:GCK72_009513 ^@ http://purl.uniprot.org/uniprot/E3LS75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Membrane http://togogenome.org/gene/31234:GCK72_013582 ^@ http://purl.uniprot.org/uniprot/E3NP45 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_011041 ^@ http://purl.uniprot.org/uniprot/E3LX11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane http://togogenome.org/gene/31234:GCK72_012720 ^@ http://purl.uniprot.org/uniprot/E3NND2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/31234:GCK72_009740 ^@ http://purl.uniprot.org/uniprot/E3LT53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.|||Cytoplasm|||Membrane http://togogenome.org/gene/31234:GCK72_022134 ^@ http://purl.uniprot.org/uniprot/E3MAE4 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/31234:GCK72_016881 ^@ http://purl.uniprot.org/uniprot/E3MHF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_016962 ^@ http://purl.uniprot.org/uniprot/E3MHC4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_010720 ^@ http://purl.uniprot.org/uniprot/E3LWX6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/31234:GCK72_017552 ^@ http://purl.uniprot.org/uniprot/E3LTN8 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_003904 ^@ http://purl.uniprot.org/uniprot/E3MU31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIF alpha subunit family.|||Nucleus|||TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. http://togogenome.org/gene/31234:GCK72_012093 ^@ http://purl.uniprot.org/uniprot/E3NBB7 ^@ Similarity ^@ Belongs to the TFIIE alpha subunit family. http://togogenome.org/gene/31234:GCK72_000650 ^@ http://purl.uniprot.org/uniprot/E3M347 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/31234:GCK72_017070 ^@ http://purl.uniprot.org/uniprot/E3NCS3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_018181 ^@ http://purl.uniprot.org/uniprot/E3LPY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_023641 ^@ http://purl.uniprot.org/uniprot/E3M248 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_014730 ^@ http://purl.uniprot.org/uniprot/E3M6Q5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_013590 ^@ http://purl.uniprot.org/uniprot/E3NLT9 ^@ Cofactor|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily.|||Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/31234:GCK72_017626 ^@ http://purl.uniprot.org/uniprot/E3LTW2 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_025746 ^@ http://purl.uniprot.org/uniprot/E3ME13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_018656 ^@ http://purl.uniprot.org/uniprot/E3M0F0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_014291 ^@ http://purl.uniprot.org/uniprot/E3MT22 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/31234:GCK72_020292 ^@ http://purl.uniprot.org/uniprot/E3LIB1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_001556 ^@ http://purl.uniprot.org/uniprot/E3N1I5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAR6 family.|||Cytoplasm|||tight junction http://togogenome.org/gene/31234:GCK72_002003 ^@ http://purl.uniprot.org/uniprot/E3LME4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/31234:GCK72_009042 ^@ http://purl.uniprot.org/uniprot/E3N6Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the anamorsin family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_023610 ^@ http://purl.uniprot.org/uniprot/E3M211 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the syndecan proteoglycan family.|||Cell surface proteoglycan.|||Membrane http://togogenome.org/gene/31234:GCK72_019496 ^@ http://purl.uniprot.org/uniprot/E3LL30 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/31234:GCK72_024033 ^@ http://purl.uniprot.org/uniprot/E3LCP4 ^@ Similarity|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/31234:GCK72_003546 ^@ http://purl.uniprot.org/uniprot/E3M8V6 ^@ Similarity ^@ Belongs to the NDRG family. http://togogenome.org/gene/31234:GCK72_011704 ^@ http://purl.uniprot.org/uniprot/E3NCN3 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_017203 ^@ http://purl.uniprot.org/uniprot/E3N527 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_002168 ^@ http://purl.uniprot.org/uniprot/E3LLW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alpha-carbonic anhydrase family.|||Membrane|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/31234:GCK72_024579 ^@ http://purl.uniprot.org/uniprot/E3LDJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/31234:GCK72_001108 ^@ http://purl.uniprot.org/uniprot/E3LXZ4 ^@ Similarity ^@ Belongs to the G-alpha family. G(s) subfamily. http://togogenome.org/gene/31234:GCK72_005968 ^@ http://purl.uniprot.org/uniprot/E3M4G5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein srb family.|||Membrane http://togogenome.org/gene/31234:GCK72_024494 ^@ http://purl.uniprot.org/uniprot/E3LDS8 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/31234:GCK72_006564 ^@ http://purl.uniprot.org/uniprot/E3LRQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CYRI family.|||Membrane http://togogenome.org/gene/31234:GCK72_023920 ^@ http://purl.uniprot.org/uniprot/E3NFN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Membrane http://togogenome.org/gene/31234:GCK72_002360 ^@ http://purl.uniprot.org/uniprot/E3LW38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/31234:GCK72_008436 ^@ http://purl.uniprot.org/uniprot/E3NAD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_024281 ^@ http://purl.uniprot.org/uniprot/E3LEF3 ^@ Similarity ^@ Belongs to the arthropod CHH/MIH/GIH/VIH hormone family. http://togogenome.org/gene/31234:GCK72_025620 ^@ http://purl.uniprot.org/uniprot/E3MC72 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/31234:GCK72_014381 ^@ http://purl.uniprot.org/uniprot/E3MM21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/31234:GCK72_017583 ^@ http://purl.uniprot.org/uniprot/E3LTR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_002620 ^@ http://purl.uniprot.org/uniprot/E3LVC2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.|||Nucleus|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/31234:GCK72_008508 ^@ http://purl.uniprot.org/uniprot/E3MXX9 ^@ Similarity ^@ Belongs to the RRM RBM42 family. http://togogenome.org/gene/31234:GCK72_013368 ^@ http://purl.uniprot.org/uniprot/E3N5L3 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. http://togogenome.org/gene/31234:GCK72_018591 ^@ http://purl.uniprot.org/uniprot/E3LPD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_021001 ^@ http://purl.uniprot.org/uniprot/E3MTK5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_000915 ^@ http://purl.uniprot.org/uniprot/E3MYF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFS5 subunit family.|||Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_021306 ^@ http://purl.uniprot.org/uniprot/E3N588 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_005999 ^@ http://purl.uniprot.org/uniprot/E3M4J4 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_025816 ^@ http://purl.uniprot.org/uniprot/E3ME88 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_019462 ^@ http://purl.uniprot.org/uniprot/E3LKX3 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Putative Notch ligand involved in the mediation of Notch signaling. http://togogenome.org/gene/31234:GCK72_001998 ^@ http://purl.uniprot.org/uniprot/E3LMF0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017929 ^@ http://purl.uniprot.org/uniprot/E3LUT4 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/31234:GCK72_016471 ^@ http://purl.uniprot.org/uniprot/E3MQX9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MRE11/RAD32 family.|||Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.|||Nucleus http://togogenome.org/gene/31234:GCK72_003431 ^@ http://purl.uniprot.org/uniprot/E3N2P4 ^@ Subcellular Location Annotation|||Subunit ^@ Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/31234:GCK72_005126 ^@ http://purl.uniprot.org/uniprot/E3LGX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF3B4 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_011898 ^@ http://purl.uniprot.org/uniprot/E3MLB2 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/31234:GCK72_005087 ^@ http://purl.uniprot.org/uniprot/E3LGU0 ^@ Similarity ^@ Belongs to the TUB family. http://togogenome.org/gene/31234:GCK72_013502 ^@ http://purl.uniprot.org/uniprot/E3MR69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001069 ^@ http://purl.uniprot.org/uniprot/E3LY32 ^@ Similarity ^@ Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family. http://togogenome.org/gene/31234:GCK72_008402 ^@ http://purl.uniprot.org/uniprot/E3NF17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_005551 ^@ http://purl.uniprot.org/uniprot/E3LFU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_019337 ^@ http://purl.uniprot.org/uniprot/E3LK22 ^@ Similarity ^@ Belongs to the annexin family. http://togogenome.org/gene/31234:GCK72_025570 ^@ http://purl.uniprot.org/uniprot/E3MCC2 ^@ Similarity ^@ Belongs to the FAM20 family. http://togogenome.org/gene/31234:GCK72_015042 ^@ http://purl.uniprot.org/uniprot/E3NRR0 ^@ Similarity ^@ Belongs to the NAPE-PLD family. http://togogenome.org/gene/31234:GCK72_021615 ^@ http://purl.uniprot.org/uniprot/E3N0I3 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/31234:GCK72_011949 ^@ http://purl.uniprot.org/uniprot/E3MKB2 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_010716 ^@ http://purl.uniprot.org/uniprot/E3LWY0 ^@ Caution|||Cofactor ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_018279 ^@ http://purl.uniprot.org/uniprot/E3LQ77 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_004870 ^@ http://purl.uniprot.org/uniprot/E3NIU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_004319 ^@ http://purl.uniprot.org/uniprot/E3NM56 ^@ Similarity ^@ Belongs to the MPI phosphatase family. http://togogenome.org/gene/31234:GCK72_006364 ^@ http://purl.uniprot.org/uniprot/E3LQS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.|||Membrane|||Peroxisome membrane http://togogenome.org/gene/31234:GCK72_020611 ^@ http://purl.uniprot.org/uniprot/E3NEK6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_020952 ^@ http://purl.uniprot.org/uniprot/E3MTE5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_004846 ^@ http://purl.uniprot.org/uniprot/E3NHC9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 3-oxoacid CoA-transferase family.|||Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_022250 ^@ http://purl.uniprot.org/uniprot/E3MA21 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Melanosome|||Membrane|||SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.|||cis-Golgi network membrane http://togogenome.org/gene/31234:GCK72_022934 ^@ http://purl.uniprot.org/uniprot/E3MLT4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_019217 ^@ http://purl.uniprot.org/uniprot/E3LLC7 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_014946 ^@ http://purl.uniprot.org/uniprot/E3M5E2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_016030 ^@ http://purl.uniprot.org/uniprot/E3NGJ8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation. http://togogenome.org/gene/31234:GCK72_021960 ^@ http://purl.uniprot.org/uniprot/E3MEY3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA1 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_017477 ^@ http://purl.uniprot.org/uniprot/E3MNE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TDE1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_000093 ^@ http://purl.uniprot.org/uniprot/E3NHT6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 47 family. http://togogenome.org/gene/31234:GCK72_024596 ^@ http://purl.uniprot.org/uniprot/E3LDH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_006752 ^@ http://purl.uniprot.org/uniprot/E3M0W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZRANB2 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_009088 ^@ http://purl.uniprot.org/uniprot/E3NI37 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_011683 ^@ http://purl.uniprot.org/uniprot/E3NAJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_001370 ^@ http://purl.uniprot.org/uniprot/E3MFM5 ^@ Similarity ^@ Belongs to the cuticular collagen family. http://togogenome.org/gene/31234:GCK72_010489 ^@ http://purl.uniprot.org/uniprot/E3LZA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_025871 ^@ http://purl.uniprot.org/uniprot/E3MEE5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_016162 ^@ http://purl.uniprot.org/uniprot/E3NBT2 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_004618 ^@ http://purl.uniprot.org/uniprot/E3MHT9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit B family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_014626 ^@ http://purl.uniprot.org/uniprot/E3NPT9 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_024637 ^@ http://purl.uniprot.org/uniprot/E3LDC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lipase maturation factor family.|||Endoplasmic reticulum membrane|||Involved in the maturation of specific proteins in the endoplasmic reticulum.|||Membrane http://togogenome.org/gene/31234:GCK72_014546 ^@ http://purl.uniprot.org/uniprot/E3M681 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/31234:GCK72_018081 ^@ http://purl.uniprot.org/uniprot/E3LPP1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_018195 ^@ http://purl.uniprot.org/uniprot/E3LPZ7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_014596 ^@ http://purl.uniprot.org/uniprot/E3M622 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_016404 ^@ http://purl.uniprot.org/uniprot/E3MQS0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_021774 ^@ http://purl.uniprot.org/uniprot/E3N6G1 ^@ Similarity ^@ Belongs to the IUNH family. http://togogenome.org/gene/31234:GCK72_015055 ^@ http://purl.uniprot.org/uniprot/E3NSX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_014136 ^@ http://purl.uniprot.org/uniprot/E3M7X6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Associates with the spliceosome.|||Nucleus|||Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. http://togogenome.org/gene/31234:GCK72_017215 ^@ http://purl.uniprot.org/uniprot/E3N515 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_005788 ^@ http://purl.uniprot.org/uniprot/E3MMT3 ^@ Similarity ^@ Belongs to the SUA5 family. http://togogenome.org/gene/31234:GCK72_002482 ^@ http://purl.uniprot.org/uniprot/E3LVR4 ^@ Function ^@ Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain. http://togogenome.org/gene/31234:GCK72_000591 ^@ http://purl.uniprot.org/uniprot/E3LKS0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_021950 ^@ http://purl.uniprot.org/uniprot/E3MEZ3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS12 family. http://togogenome.org/gene/31234:GCK72_006097 ^@ http://purl.uniprot.org/uniprot/E3M4T8 ^@ Similarity|||Subunit ^@ Belongs to the complex I NDUFB5 subunit family.|||Complex I is composed of 45 different subunits. http://togogenome.org/gene/31234:GCK72_024263 ^@ http://purl.uniprot.org/uniprot/E3LEH0 ^@ Similarity ^@ Belongs to the WD repeat ATG16 family. http://togogenome.org/gene/31234:GCK72_002631 ^@ http://purl.uniprot.org/uniprot/E3LVB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM170 family.|||Membrane http://togogenome.org/gene/31234:GCK72_018986 ^@ http://purl.uniprot.org/uniprot/E3M002 ^@ Caution|||Similarity ^@ Belongs to the globin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_018042 ^@ http://purl.uniprot.org/uniprot/E3LPK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 6 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_010959 ^@ http://purl.uniprot.org/uniprot/E3LW69 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 5A family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_002097 ^@ http://purl.uniprot.org/uniprot/E3LM39 ^@ Similarity ^@ Belongs to the COG1 family. http://togogenome.org/gene/31234:GCK72_016126 ^@ http://purl.uniprot.org/uniprot/E3N9U2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the myo-inositol oxygenase family.|||Binds 2 iron ions per subunit.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_019453 ^@ http://purl.uniprot.org/uniprot/E3LKW4 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/31234:GCK72_005579 ^@ http://purl.uniprot.org/uniprot/E3LFX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/31234:GCK72_006425 ^@ http://purl.uniprot.org/uniprot/E3LQK8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with the pre-60S ribosomal particle.|||Belongs to the universal ribosomal protein uL10 family.|||Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.|||Cytoplasm|||nucleolus http://togogenome.org/gene/31234:GCK72_002822 ^@ http://purl.uniprot.org/uniprot/E3MVU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 18 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_018845 ^@ http://purl.uniprot.org/uniprot/E3LZT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PGAP2 family.|||Membrane http://togogenome.org/gene/31234:GCK72_023412 ^@ http://purl.uniprot.org/uniprot/E3MAL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_015403 ^@ http://purl.uniprot.org/uniprot/E3NLQ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA12 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_004307 ^@ http://purl.uniprot.org/uniprot/E3NE66 ^@ Similarity ^@ Belongs to the acid ceramidase family. http://togogenome.org/gene/31234:GCK72_019553 ^@ http://purl.uniprot.org/uniprot/E3LLB4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. http://togogenome.org/gene/31234:GCK72_024576 ^@ http://purl.uniprot.org/uniprot/E3LDJ3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMP family.|||Endosome membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_019258 ^@ http://purl.uniprot.org/uniprot/E3LLI7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. http://togogenome.org/gene/31234:GCK72_004920 ^@ http://purl.uniprot.org/uniprot/E3LGD2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_002386 ^@ http://purl.uniprot.org/uniprot/E3LW14 ^@ Similarity ^@ Belongs to the IFT57 family. http://togogenome.org/gene/31234:GCK72_009340 ^@ http://purl.uniprot.org/uniprot/E3N037 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chondroitin N-acetylgalactosaminyltransferase family.|||Golgi stack membrane|||Membrane http://togogenome.org/gene/31234:GCK72_024536 ^@ http://purl.uniprot.org/uniprot/E3LDN2 ^@ Similarity ^@ Belongs to the MTFP1 family. http://togogenome.org/gene/31234:GCK72_022949 ^@ http://purl.uniprot.org/uniprot/E3N8D2 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_006638 ^@ http://purl.uniprot.org/uniprot/E3LRI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/31234:GCK72_018646 ^@ http://purl.uniprot.org/uniprot/E3M0D5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_025258 ^@ http://purl.uniprot.org/uniprot/E3MUG5 ^@ Similarity ^@ Belongs to the troponin T family. http://togogenome.org/gene/31234:GCK72_022257 ^@ http://purl.uniprot.org/uniprot/E3MA15 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_005471 ^@ http://purl.uniprot.org/uniprot/E3LFK6 ^@ Function|||Similarity ^@ Belongs to the DPH1/DPH2 family. DPH2 subfamily.|||Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit. http://togogenome.org/gene/31234:GCK72_009749 ^@ http://purl.uniprot.org/uniprot/E3LT43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein disulfide isomerase family.|||Endoplasmic reticulum lumen http://togogenome.org/gene/31234:GCK72_010722 ^@ http://purl.uniprot.org/uniprot/E3LWX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.|||Nucleus http://togogenome.org/gene/31234:GCK72_023834 ^@ http://purl.uniprot.org/uniprot/E3M285 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERGIC family.|||Endoplasmic reticulum-Golgi intermediate compartment membrane http://togogenome.org/gene/31234:GCK72_005664 ^@ http://purl.uniprot.org/uniprot/E3LG68 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFS-II family.|||Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.|||Nucleus http://togogenome.org/gene/31234:GCK72_004299 ^@ http://purl.uniprot.org/uniprot/E3NE73 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/31234:GCK72_014205 ^@ http://purl.uniprot.org/uniprot/E3MST8 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_014576 ^@ http://purl.uniprot.org/uniprot/E3M649 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/31234:GCK72_018388 ^@ http://purl.uniprot.org/uniprot/E3LNR1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL28 family. http://togogenome.org/gene/31234:GCK72_002263 ^@ http://purl.uniprot.org/uniprot/E3MGH8 ^@ Similarity ^@ Belongs to the CAP family. http://togogenome.org/gene/31234:GCK72_025038 ^@ http://purl.uniprot.org/uniprot/E3MRT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_006092 ^@ http://purl.uniprot.org/uniprot/E3M4T4 ^@ Similarity ^@ Belongs to the FAX family. http://togogenome.org/gene/31234:GCK72_009455 ^@ http://purl.uniprot.org/uniprot/E3LSD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eIF-2B alpha/beta/delta subunits family.|||Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.|||Complex of five different subunits; alpha, beta, gamma, delta and epsilon. http://togogenome.org/gene/31234:GCK72_018871 ^@ http://purl.uniprot.org/uniprot/E3LKS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_022517 ^@ http://purl.uniprot.org/uniprot/E3N4X2 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/31234:GCK72_020616 ^@ http://purl.uniprot.org/uniprot/E3NEK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_020959 ^@ http://purl.uniprot.org/uniprot/E3MTD1 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/31234:GCK72_024412 ^@ http://purl.uniprot.org/uniprot/E3LE20 ^@ Similarity ^@ Belongs to the profilin family. http://togogenome.org/gene/31234:GCK72_016453 ^@ http://purl.uniprot.org/uniprot/E3MQW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TIM50 family.|||Component of the TIM23 complex.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_025587 ^@ http://purl.uniprot.org/uniprot/E3MCA6 ^@ Function|||Similarity ^@ Belongs to the phospholipase B-like family.|||Putative phospholipase. http://togogenome.org/gene/31234:GCK72_013513 ^@ http://purl.uniprot.org/uniprot/E3MR62 ^@ Similarity ^@ Belongs to the CGI121/TPRKB family. http://togogenome.org/gene/31234:GCK72_004898 ^@ http://purl.uniprot.org/uniprot/E3LGA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM47 family.|||Membrane http://togogenome.org/gene/31234:GCK72_004003 ^@ http://purl.uniprot.org/uniprot/E3MQK7 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/31234:GCK72_003418 ^@ http://purl.uniprot.org/uniprot/E3N2N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-CoA oxidase family.|||Peroxisome http://togogenome.org/gene/31234:GCK72_017861 ^@ http://purl.uniprot.org/uniprot/E3LUL1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PGAP3 family.|||Golgi apparatus membrane|||Involved in the lipid remodeling steps of GPI-anchor maturation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_006124 ^@ http://purl.uniprot.org/uniprot/E3M4W4 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/31234:GCK72_002533 ^@ http://purl.uniprot.org/uniprot/E3LVL4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/31234:GCK72_019997 ^@ http://purl.uniprot.org/uniprot/E3LHC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_000153 ^@ http://purl.uniprot.org/uniprot/E3NE13 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_024562 ^@ http://purl.uniprot.org/uniprot/E3LDK7 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_024684 ^@ http://purl.uniprot.org/uniprot/E3LD75 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_010257 ^@ http://purl.uniprot.org/uniprot/E3MIF5 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_001174 ^@ http://purl.uniprot.org/uniprot/E3LXS8 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/31234:GCK72_023514 ^@ http://purl.uniprot.org/uniprot/E3MMP3 ^@ Similarity ^@ Belongs to the aldolase class II family. Adducin subfamily. http://togogenome.org/gene/31234:GCK72_001804 ^@ http://purl.uniprot.org/uniprot/E3LLN2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_024518 ^@ http://purl.uniprot.org/uniprot/E3LDQ3 ^@ Similarity ^@ Belongs to the TEX28 family. http://togogenome.org/gene/31234:GCK72_014167 ^@ http://purl.uniprot.org/uniprot/E3M810 ^@ Similarity ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. http://togogenome.org/gene/31234:GCK72_013586 ^@ http://purl.uniprot.org/uniprot/E3NT57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty-acid and retinol-binding protein (FARBP) family.|||Secreted http://togogenome.org/gene/31234:GCK72_021199 ^@ http://purl.uniprot.org/uniprot/E3NBF2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017507 ^@ http://purl.uniprot.org/uniprot/E3LTJ3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_024116 ^@ http://purl.uniprot.org/uniprot/E3LEW7 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/31234:GCK72_013866 ^@ http://purl.uniprot.org/uniprot/E3M753 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_014391 ^@ http://purl.uniprot.org/uniprot/E3MM11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||extracellular matrix http://togogenome.org/gene/31234:GCK72_004426 ^@ http://purl.uniprot.org/uniprot/E3N1A1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_017938 ^@ http://purl.uniprot.org/uniprot/E3LUU3 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/31234:GCK72_005732 ^@ http://purl.uniprot.org/uniprot/E3MN00 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_016533 ^@ http://purl.uniprot.org/uniprot/E3MTZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ISY1 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_020186 ^@ http://purl.uniprot.org/uniprot/E3LHX5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_018034 ^@ http://purl.uniprot.org/uniprot/E3LPJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_014073 ^@ http://purl.uniprot.org/uniprot/E3M7R3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxin-14 family.|||Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.|||Peroxisome membrane http://togogenome.org/gene/31234:GCK72_005336 ^@ http://purl.uniprot.org/uniprot/E3LF82 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_016635 ^@ http://purl.uniprot.org/uniprot/E3NGS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.|||Membrane http://togogenome.org/gene/31234:GCK72_019599 ^@ http://purl.uniprot.org/uniprot/E3LJN3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL38 family. http://togogenome.org/gene/31234:GCK72_019612 ^@ http://purl.uniprot.org/uniprot/E3LJP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Membrane http://togogenome.org/gene/31234:GCK72_013838 ^@ http://purl.uniprot.org/uniprot/E3NMW0 ^@ Caution|||Similarity ^@ Belongs to the nematode receptor-like protein srg family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_014068 ^@ http://purl.uniprot.org/uniprot/E3M7Q7 ^@ Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/31234:GCK72_008775 ^@ http://purl.uniprot.org/uniprot/E3M825 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the anoctamin family.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_022940 ^@ http://purl.uniprot.org/uniprot/E3MLU2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_025080 ^@ http://purl.uniprot.org/uniprot/E3NAQ8 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_019887 ^@ http://purl.uniprot.org/uniprot/E3LJE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_011795 ^@ http://purl.uniprot.org/uniprot/E3MSN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_013472 ^@ http://purl.uniprot.org/uniprot/E3MRA9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_014000 ^@ http://purl.uniprot.org/uniprot/E3M7I2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC6 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_001603 ^@ http://purl.uniprot.org/uniprot/E3LNC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_004240 ^@ http://purl.uniprot.org/uniprot/E3MQ14 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001239 ^@ http://purl.uniprot.org/uniprot/E3LXK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP19 family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_013346 ^@ http://purl.uniprot.org/uniprot/E3MRC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_001016 ^@ http://purl.uniprot.org/uniprot/E3LY79 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/31234:GCK72_021332 ^@ http://purl.uniprot.org/uniprot/E3N8K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/31234:GCK72_019046 ^@ http://purl.uniprot.org/uniprot/E3LKA7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_007727 ^@ http://purl.uniprot.org/uniprot/E3M9L6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_000096 ^@ http://purl.uniprot.org/uniprot/E3NHT4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.|||Belongs to the NMD3 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_004722 ^@ http://purl.uniprot.org/uniprot/E3N379 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM41 family.|||Membrane http://togogenome.org/gene/31234:GCK72_014968 ^@ http://purl.uniprot.org/uniprot/E3M5G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GST superfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_000692 ^@ http://purl.uniprot.org/uniprot/E3M398 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chondroitin N-acetylgalactosaminyltransferase family.|||Golgi stack membrane|||Membrane http://togogenome.org/gene/31234:GCK72_002389 ^@ http://purl.uniprot.org/uniprot/E3LW11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_019607 ^@ http://purl.uniprot.org/uniprot/E3LJP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. http://togogenome.org/gene/31234:GCK72_009983 ^@ http://purl.uniprot.org/uniprot/E3MCM0 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RPB8 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/31234:GCK72_022040 ^@ http://purl.uniprot.org/uniprot/E3NB65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_001987 ^@ http://purl.uniprot.org/uniprot/E3LMG5 ^@ Similarity|||Subunit ^@ Belongs to the ODC antizyme family.|||Interacts with ODC1 and thereby sterically blocks ODC homodimerization. http://togogenome.org/gene/31234:GCK72_000217 ^@ http://purl.uniprot.org/uniprot/E3NGY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ACDP family.|||Cell membrane|||Metal transporter. http://togogenome.org/gene/31234:GCK72_013361 ^@ http://purl.uniprot.org/uniprot/E3NHI2 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/31234:GCK72_005635 ^@ http://purl.uniprot.org/uniprot/E3LG35 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB3 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_005789 ^@ http://purl.uniprot.org/uniprot/E3MMT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/31234:GCK72_018270 ^@ http://purl.uniprot.org/uniprot/E3LQ70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase e subunit family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_015127 ^@ http://purl.uniprot.org/uniprot/E3NVE6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_014922 ^@ http://purl.uniprot.org/uniprot/E3M5B1 ^@ Similarity ^@ Belongs to the thymidine kinase family. http://togogenome.org/gene/31234:GCK72_003588 ^@ http://purl.uniprot.org/uniprot/E3M8Z1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS26 family. http://togogenome.org/gene/31234:GCK72_015383 ^@ http://purl.uniprot.org/uniprot/E3N897 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_008049 ^@ http://purl.uniprot.org/uniprot/E3MDQ4 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/31234:GCK72_000393 ^@ http://purl.uniprot.org/uniprot/E3N7Q3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_024600 ^@ http://purl.uniprot.org/uniprot/E3LDG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Membrane http://togogenome.org/gene/31234:GCK72_004495 ^@ http://purl.uniprot.org/uniprot/E3MS03 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_000970 ^@ http://purl.uniprot.org/uniprot/E3LYD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP16 family.|||nucleolus http://togogenome.org/gene/31234:GCK72_004561 ^@ http://purl.uniprot.org/uniprot/E3MHX1 ^@ Similarity ^@ In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.|||In the N-terminal section; belongs to the SAICAR synthetase family. http://togogenome.org/gene/31234:GCK72_007996 ^@ http://purl.uniprot.org/uniprot/E3MDD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC37 family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_016617 ^@ http://purl.uniprot.org/uniprot/E3MTQ9 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/31234:GCK72_025602 ^@ http://purl.uniprot.org/uniprot/E3MC91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMDT1/EMRE family.|||Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.|||Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_017638 ^@ http://purl.uniprot.org/uniprot/E3LTX6 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/31234:GCK72_024437 ^@ http://purl.uniprot.org/uniprot/E3LDY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_008884 ^@ http://purl.uniprot.org/uniprot/E3M8B4 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/31234:GCK72_005779 ^@ http://purl.uniprot.org/uniprot/E3MMU3 ^@ Function|||Similarity|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA7 subunit family.|||Complex I is composed of 45 different subunits. http://togogenome.org/gene/31234:GCK72_022237 ^@ http://purl.uniprot.org/uniprot/E3MA36 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_018094 ^@ http://purl.uniprot.org/uniprot/E3LPQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NDC1 family.|||Membrane|||Nucleus membrane|||nuclear pore complex http://togogenome.org/gene/31234:GCK72_010858 ^@ http://purl.uniprot.org/uniprot/E3LWH7 ^@ Similarity ^@ Belongs to the acid ceramidase family. http://togogenome.org/gene/31234:GCK72_019372 ^@ http://purl.uniprot.org/uniprot/E3LKC4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_024919 ^@ http://purl.uniprot.org/uniprot/E3MVJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. LDAH family.|||Lipid droplet http://togogenome.org/gene/31234:GCK72_010314 ^@ http://purl.uniprot.org/uniprot/E3LYN2 ^@ Similarity ^@ Belongs to the IPI1/TEX10 family. http://togogenome.org/gene/31234:GCK72_001595 ^@ http://purl.uniprot.org/uniprot/E3LNC9 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/31234:GCK72_008999 ^@ http://purl.uniprot.org/uniprot/E3MWF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_023623 ^@ http://purl.uniprot.org/uniprot/E3M233 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/31234:GCK72_010488 ^@ http://purl.uniprot.org/uniprot/E3LZA1 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_018275 ^@ http://purl.uniprot.org/uniprot/E3LQ73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom20 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/31234:GCK72_001514 ^@ http://purl.uniprot.org/uniprot/E3N1M4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_019551 ^@ http://purl.uniprot.org/uniprot/E3LLB2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. http://togogenome.org/gene/31234:GCK72_000337 ^@ http://purl.uniprot.org/uniprot/E3MX98 ^@ Function|||Similarity ^@ Belongs to the phospholipid scramblase family.|||May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. http://togogenome.org/gene/31234:GCK72_016655 ^@ http://purl.uniprot.org/uniprot/E3NHM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Membrane http://togogenome.org/gene/31234:GCK72_011078 ^@ http://purl.uniprot.org/uniprot/E3N311 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/31234:GCK72_002066 ^@ http://purl.uniprot.org/uniprot/E3LM76 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit alpha family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/31234:GCK72_014083 ^@ http://purl.uniprot.org/uniprot/E3M7S5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.|||Belongs to the carbohydrate kinase PfkB family.|||Binds 3 Mg(2+) ions per subunit.|||Monomer.|||Nucleus http://togogenome.org/gene/31234:GCK72_010709 ^@ http://purl.uniprot.org/uniprot/E3LWY9 ^@ Function|||Similarity ^@ Belongs to the SHMT family.|||Interconversion of serine and glycine. http://togogenome.org/gene/31234:GCK72_017704 ^@ http://purl.uniprot.org/uniprot/E3LU47 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_000980 ^@ http://purl.uniprot.org/uniprot/E3LYC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nucleoporin Nup85 family.|||Component of the nuclear pore complex (NPC).|||Functions as a component of the nuclear pore complex (NPC).|||Nucleus membrane|||nuclear pore complex http://togogenome.org/gene/31234:GCK72_018581 ^@ http://purl.uniprot.org/uniprot/E3LPB9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I LYR family. SDHAF3 subfamily.|||Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.|||Mitochondrion matrix|||Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1. http://togogenome.org/gene/31234:GCK72_006196 ^@ http://purl.uniprot.org/uniprot/E3LRA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_009481 ^@ http://purl.uniprot.org/uniprot/E3LSA7 ^@ Similarity ^@ Belongs to the eukaryotic-type primase small subunit family. http://togogenome.org/gene/31234:GCK72_000929 ^@ http://purl.uniprot.org/uniprot/E3MYG8 ^@ Similarity ^@ Belongs to the ATP:guanido phosphotransferase family. http://togogenome.org/gene/31234:GCK72_006150 ^@ http://purl.uniprot.org/uniprot/E3LRF2 ^@ Similarity ^@ Belongs to the glycosyltransferase 2 family. http://togogenome.org/gene/31234:GCK72_013721 ^@ http://purl.uniprot.org/uniprot/E3N416 ^@ Caution|||Similarity ^@ Belongs to the nematode receptor-like protein srg family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_001583 ^@ http://purl.uniprot.org/uniprot/E3LNE2 ^@ Function|||Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Plays an important role in regulating the size of autophagosomes during the formation process. http://togogenome.org/gene/31234:GCK72_014314 ^@ http://purl.uniprot.org/uniprot/E3MMB2 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_010159 ^@ http://purl.uniprot.org/uniprot/E3MI25 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/31234:GCK72_016198 ^@ http://purl.uniprot.org/uniprot/E3NHX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Cell membrane|||Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.|||Membrane http://togogenome.org/gene/31234:GCK72_025531 ^@ http://purl.uniprot.org/uniprot/E3MCF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_024585 ^@ http://purl.uniprot.org/uniprot/E3LDI5 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/31234:GCK72_013412 ^@ http://purl.uniprot.org/uniprot/E3N5R0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_018188 ^@ http://purl.uniprot.org/uniprot/E3LPZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_016609 ^@ http://purl.uniprot.org/uniprot/E3MTR6 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_009827 ^@ http://purl.uniprot.org/uniprot/E3LSX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eS21 family.|||Endoplasmic reticulum|||Rough endoplasmic reticulum|||cytosol http://togogenome.org/gene/31234:GCK72_005114 ^@ http://purl.uniprot.org/uniprot/E3LGW5 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/31234:GCK72_005410 ^@ http://purl.uniprot.org/uniprot/E3LFF0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/31234:GCK72_024321 ^@ http://purl.uniprot.org/uniprot/E3LEB1 ^@ Similarity ^@ Belongs to the CCDC22 family. http://togogenome.org/gene/31234:GCK72_005794 ^@ http://purl.uniprot.org/uniprot/E3MMS5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_000027 ^@ http://purl.uniprot.org/uniprot/E3MT65 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/31234:GCK72_025554 ^@ http://purl.uniprot.org/uniprot/E3MCD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005038 ^@ http://purl.uniprot.org/uniprot/E3LGP0 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/31234:GCK72_000562 ^@ http://purl.uniprot.org/uniprot/E3M3T7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/31234:GCK72_024262 ^@ http://purl.uniprot.org/uniprot/E3LEH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cell membrane|||coated pit http://togogenome.org/gene/31234:GCK72_008507 ^@ http://purl.uniprot.org/uniprot/E3MXY0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_025713 ^@ http://purl.uniprot.org/uniprot/E3MDX7 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_018232 ^@ http://purl.uniprot.org/uniprot/E3LQ32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_006466 ^@ http://purl.uniprot.org/uniprot/E3LQG4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_019991 ^@ http://purl.uniprot.org/uniprot/E3LHC0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_023760 ^@ http://purl.uniprot.org/uniprot/E3M2W1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK1 subfamily.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Monomer. http://togogenome.org/gene/31234:GCK72_013762 ^@ http://purl.uniprot.org/uniprot/E3N3W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/31234:GCK72_002600 ^@ http://purl.uniprot.org/uniprot/E3LVE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_004433 ^@ http://purl.uniprot.org/uniprot/E3N194 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_013894 ^@ http://purl.uniprot.org/uniprot/E3M778 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/31234:GCK72_013551 ^@ http://purl.uniprot.org/uniprot/E3MR22 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_010841 ^@ http://purl.uniprot.org/uniprot/E3LWJ8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_010329 ^@ http://purl.uniprot.org/uniprot/E3LYL5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Common component of the spliceosome and rRNA processing machinery.|||nucleolus http://togogenome.org/gene/31234:GCK72_004725 ^@ http://purl.uniprot.org/uniprot/E3N382 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit F family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_002119 ^@ http://purl.uniprot.org/uniprot/E3LM16 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/31234:GCK72_025299 ^@ http://purl.uniprot.org/uniprot/E3MUC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane http://togogenome.org/gene/31234:GCK72_023875 ^@ http://purl.uniprot.org/uniprot/E3M2G7 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_009276 ^@ http://purl.uniprot.org/uniprot/E3N095 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_017971 ^@ http://purl.uniprot.org/uniprot/E3LTF4 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/31234:GCK72_017806 ^@ http://purl.uniprot.org/uniprot/E3LUF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_006695 ^@ http://purl.uniprot.org/uniprot/E3M151 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_000867 ^@ http://purl.uniprot.org/uniprot/E3N4R5 ^@ Similarity ^@ Belongs to the SPATS2 family. http://togogenome.org/gene/31234:GCK72_019342 ^@ http://purl.uniprot.org/uniprot/E3LK28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_025764 ^@ http://purl.uniprot.org/uniprot/E3ME32 ^@ Function|||Similarity ^@ Belongs to the 5'-AMP-activated protein kinase beta subunit family.|||Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). http://togogenome.org/gene/31234:GCK72_015839 ^@ http://purl.uniprot.org/uniprot/E3N5G7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Nucleus http://togogenome.org/gene/31234:GCK72_006966 ^@ http://purl.uniprot.org/uniprot/E3M1J8 ^@ Similarity ^@ Belongs to the argonaute family. http://togogenome.org/gene/31234:GCK72_010070 ^@ http://purl.uniprot.org/uniprot/E3MCW8 ^@ Function|||Similarity ^@ Belongs to the E(R) family.|||May have a role in the cell cycle. http://togogenome.org/gene/31234:GCK72_016423 ^@ http://purl.uniprot.org/uniprot/E3MQT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Nucleus http://togogenome.org/gene/31234:GCK72_011739 ^@ http://purl.uniprot.org/uniprot/E3MSH5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the splicing factor SR family.|||Necessary for the splicing of pre-mRNA.|||Nucleus http://togogenome.org/gene/31234:GCK72_020504 ^@ http://purl.uniprot.org/uniprot/E3LJ30 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001824 ^@ http://purl.uniprot.org/uniprot/E3LMY6 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/31234:GCK72_023172 ^@ http://purl.uniprot.org/uniprot/E3MKC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_006324 ^@ http://purl.uniprot.org/uniprot/E3LQX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001975 ^@ http://purl.uniprot.org/uniprot/E3LMH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_001802 ^@ http://purl.uniprot.org/uniprot/E3LLN4 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Nucleus membrane|||Rough endoplasmic reticulum membrane http://togogenome.org/gene/31234:GCK72_013861 ^@ http://purl.uniprot.org/uniprot/E3M750 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_006922 ^@ http://purl.uniprot.org/uniprot/E3M1N7 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/31234:GCK72_017907 ^@ http://purl.uniprot.org/uniprot/E3LUR0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_002397 ^@ http://purl.uniprot.org/uniprot/E3LW03 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/31234:GCK72_023218 ^@ http://purl.uniprot.org/uniprot/E3MAN8 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/31234:GCK72_018852 ^@ http://purl.uniprot.org/uniprot/E3LZT9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL4 family. http://togogenome.org/gene/31234:GCK72_020078 ^@ http://purl.uniprot.org/uniprot/E3LHL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_025222 ^@ http://purl.uniprot.org/uniprot/E3NDY3 ^@ Similarity ^@ Belongs to the TENT family. http://togogenome.org/gene/31234:GCK72_003719 ^@ http://purl.uniprot.org/uniprot/E3N2T3 ^@ Caution|||Similarity ^@ Belongs to the peptidase C2 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_025516 ^@ http://purl.uniprot.org/uniprot/E3MCH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/31234:GCK72_014639 ^@ http://purl.uniprot.org/uniprot/E3M703 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit alpha family. http://togogenome.org/gene/31234:GCK72_001840 ^@ http://purl.uniprot.org/uniprot/E3LMW9 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/31234:GCK72_008911 ^@ http://purl.uniprot.org/uniprot/E3N6N5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family. Pelota subfamily.|||Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_018079 ^@ http://purl.uniprot.org/uniprot/E3LPN9 ^@ Similarity ^@ Belongs to the SNW family. http://togogenome.org/gene/31234:GCK72_002091 ^@ http://purl.uniprot.org/uniprot/E3LM48 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_009294 ^@ http://purl.uniprot.org/uniprot/E3N084 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit D family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.|||mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs. http://togogenome.org/gene/31234:GCK72_022114 ^@ http://purl.uniprot.org/uniprot/E3MAG3 ^@ Similarity ^@ Belongs to the peptidase M28 family. M28B subfamily. http://togogenome.org/gene/31234:GCK72_010857 ^@ http://purl.uniprot.org/uniprot/E3LWH9 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_023274 ^@ http://purl.uniprot.org/uniprot/E3MAU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_020180 ^@ http://purl.uniprot.org/uniprot/E3LHW9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_017596 ^@ http://purl.uniprot.org/uniprot/E3LTT3 ^@ Similarity ^@ Belongs to the EIF1AD family. http://togogenome.org/gene/31234:GCK72_013086 ^@ http://purl.uniprot.org/uniprot/E3MTK8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_026055 ^@ http://purl.uniprot.org/uniprot/E3MPC5 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_014888 ^@ http://purl.uniprot.org/uniprot/E3NRK6 ^@ Caution|||Similarity ^@ Belongs to the peptidase C2 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_006254 ^@ http://purl.uniprot.org/uniprot/E3LR51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_022159 ^@ http://purl.uniprot.org/uniprot/E3MAC0 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/31234:GCK72_005659 ^@ http://purl.uniprot.org/uniprot/E3LG63 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_006586 ^@ http://purl.uniprot.org/uniprot/E3LRN3 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_014131 ^@ http://purl.uniprot.org/uniprot/E3NLE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the taffazin family.|||Mitochondrion inner membrane|||Mitochondrion outer membrane http://togogenome.org/gene/31234:GCK72_014890 ^@ http://purl.uniprot.org/uniprot/E3M577 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/31234:GCK72_010478 ^@ http://purl.uniprot.org/uniprot/E3LZB0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_006670 ^@ http://purl.uniprot.org/uniprot/E3M1A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM38 family.|||Membrane http://togogenome.org/gene/31234:GCK72_011689 ^@ http://purl.uniprot.org/uniprot/E3NAK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_014275 ^@ http://purl.uniprot.org/uniprot/E3MT05 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/31234:GCK72_013304 ^@ http://purl.uniprot.org/uniprot/E3MRH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/31234:GCK72_004938 ^@ http://purl.uniprot.org/uniprot/E3LGF1 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_001501 ^@ http://purl.uniprot.org/uniprot/E3N1N7 ^@ Function|||Similarity ^@ Belongs to the phage and mitochondrial RNA polymerase family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/31234:GCK72_010218 ^@ http://purl.uniprot.org/uniprot/E3MIB4 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_009147 ^@ http://purl.uniprot.org/uniprot/E3MKW3 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_008975 ^@ http://purl.uniprot.org/uniprot/E3MWD3 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/31234:GCK72_001550 ^@ http://purl.uniprot.org/uniprot/E3N1J2 ^@ Similarity ^@ Belongs to the mTERF family. http://togogenome.org/gene/31234:GCK72_013768 ^@ http://purl.uniprot.org/uniprot/E3N3W2 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. http://togogenome.org/gene/31234:GCK72_015694 ^@ http://purl.uniprot.org/uniprot/E3N906 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_024778 ^@ http://purl.uniprot.org/uniprot/E3LCV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad21 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_018163 ^@ http://purl.uniprot.org/uniprot/E3LPX1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. http://togogenome.org/gene/31234:GCK72_004975 ^@ http://purl.uniprot.org/uniprot/E3LGI4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_024559 ^@ http://purl.uniprot.org/uniprot/E3LDK9 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_001857 ^@ http://purl.uniprot.org/uniprot/E3LMV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/31234:GCK72_001033 ^@ http://purl.uniprot.org/uniprot/E3LY65 ^@ Function|||Similarity ^@ Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.|||Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_014059 ^@ http://purl.uniprot.org/uniprot/E3M7P6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS7 family. http://togogenome.org/gene/31234:GCK72_014403 ^@ http://purl.uniprot.org/uniprot/E3MLZ8 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily. http://togogenome.org/gene/31234:GCK72_013534 ^@ http://purl.uniprot.org/uniprot/E3MR41 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_002911 ^@ http://purl.uniprot.org/uniprot/E3MXK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_025595 ^@ http://purl.uniprot.org/uniprot/E3MC98 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_011622 ^@ http://purl.uniprot.org/uniprot/E3MNL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM120 family.|||Membrane http://togogenome.org/gene/31234:GCK72_001878 ^@ http://purl.uniprot.org/uniprot/E3LMT1 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/31234:GCK72_004463 ^@ http://purl.uniprot.org/uniprot/E3MRX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COA3 family.|||Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.|||Membrane|||Required for assembly of cytochrome c oxidase (complex IV). http://togogenome.org/gene/31234:GCK72_013169 ^@ http://purl.uniprot.org/uniprot/E3NCG1 ^@ Similarity ^@ Belongs to the UPF0375 family. http://togogenome.org/gene/31234:GCK72_009623 ^@ http://purl.uniprot.org/uniprot/E3LRW0 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/31234:GCK72_013685 ^@ http://purl.uniprot.org/uniprot/E3MS83 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_003118 ^@ http://purl.uniprot.org/uniprot/E3N8Z1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_001786 ^@ http://purl.uniprot.org/uniprot/E3N434 ^@ Similarity ^@ Belongs to the CC2D1 family. http://togogenome.org/gene/31234:GCK72_014183 ^@ http://purl.uniprot.org/uniprot/E3MSR4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001433 ^@ http://purl.uniprot.org/uniprot/E3MFF0 ^@ Similarity ^@ Belongs to the HTATSF1 family. http://togogenome.org/gene/31234:GCK72_013692 ^@ http://purl.uniprot.org/uniprot/E3MS76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRP4 family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_012881 ^@ http://purl.uniprot.org/uniprot/E3NC53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VTI1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_023598 ^@ http://purl.uniprot.org/uniprot/E3M2Z1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001512 ^@ http://purl.uniprot.org/uniprot/E3N1M6 ^@ Subcellular Location Annotation|||Subunit ^@ Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/31234:GCK72_017445 ^@ http://purl.uniprot.org/uniprot/E3MNA8 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/31234:GCK72_019883 ^@ http://purl.uniprot.org/uniprot/E3LJE0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_012867 ^@ http://purl.uniprot.org/uniprot/E3NC66 ^@ Subcellular Location Annotation ^@ Lysosome membrane http://togogenome.org/gene/31234:GCK72_018264 ^@ http://purl.uniprot.org/uniprot/E3LQ58 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_023221 ^@ http://purl.uniprot.org/uniprot/E3MAP1 ^@ Similarity ^@ Belongs to the CAP family. http://togogenome.org/gene/31234:GCK72_014773 ^@ http://purl.uniprot.org/uniprot/E3NNG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynactin subunit 4 family.|||cell cortex|||centrosome|||sarcomere|||stress fiber http://togogenome.org/gene/31234:GCK72_005874 ^@ http://purl.uniprot.org/uniprot/E3M463 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_019787 ^@ http://purl.uniprot.org/uniprot/E3LIZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_009302 ^@ http://purl.uniprot.org/uniprot/E3N078 ^@ Similarity ^@ Belongs to the lin-9 family. http://togogenome.org/gene/31234:GCK72_024363 ^@ http://purl.uniprot.org/uniprot/E3LE69 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M2 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/31234:GCK72_018317 ^@ http://purl.uniprot.org/uniprot/E3LNJ2 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_002826 ^@ http://purl.uniprot.org/uniprot/E3MVU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 18 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_016943 ^@ http://purl.uniprot.org/uniprot/E3MHM9 ^@ Similarity ^@ Belongs to the ZNF277 family. http://togogenome.org/gene/31234:GCK72_013916 ^@ http://purl.uniprot.org/uniprot/E3M796 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_016422 ^@ http://purl.uniprot.org/uniprot/E3MQT6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_021863 ^@ http://purl.uniprot.org/uniprot/E3MF79 ^@ Similarity ^@ Belongs to the SNAP family. http://togogenome.org/gene/31234:GCK72_002203 ^@ http://purl.uniprot.org/uniprot/E3MGB4 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/31234:GCK72_014834 ^@ http://purl.uniprot.org/uniprot/E3M513 ^@ Similarity ^@ Belongs to the ric-3 family. http://togogenome.org/gene/31234:GCK72_002001 ^@ http://purl.uniprot.org/uniprot/E3LME7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_021770 ^@ http://purl.uniprot.org/uniprot/E3N6G7 ^@ Similarity ^@ Belongs to the GSKIP family. http://togogenome.org/gene/31234:GCK72_022031 ^@ http://purl.uniprot.org/uniprot/E3NB59 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.|||Cytoplasm|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||In the N-terminal section; belongs to the flavodoxin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of the anamorsin/DRE2 homolog, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. http://togogenome.org/gene/31234:GCK72_016644 ^@ http://purl.uniprot.org/uniprot/E3NGR0 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srg family. http://togogenome.org/gene/31234:GCK72_017185 ^@ http://purl.uniprot.org/uniprot/E3N546 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/31234:GCK72_016629 ^@ http://purl.uniprot.org/uniprot/E3NGS8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.|||Endoplasmic reticulum membrane|||Homodimer or homotetramer; both forms have similar enzymatic activities.|||Membrane http://togogenome.org/gene/31234:GCK72_000042 ^@ http://purl.uniprot.org/uniprot/E3MT50 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion matrix|||The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/31234:GCK72_003433 ^@ http://purl.uniprot.org/uniprot/E3N2P5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/31234:GCK72_025518 ^@ http://purl.uniprot.org/uniprot/E3MCH4 ^@ Similarity ^@ Belongs to the complex I 49 kDa subunit family. http://togogenome.org/gene/31234:GCK72_009335 ^@ http://purl.uniprot.org/uniprot/E3N043 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin alpha chain family.|||Membrane http://togogenome.org/gene/31234:GCK72_025389 ^@ http://purl.uniprot.org/uniprot/E3MJP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/31234:GCK72_001243 ^@ http://purl.uniprot.org/uniprot/E3LXK1 ^@ Similarity ^@ Belongs to the Integrator subunit 3 family. http://togogenome.org/gene/31234:GCK72_008701 ^@ http://purl.uniprot.org/uniprot/E3M8A7 ^@ Cofactor|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/31234:GCK72_009717 ^@ http://purl.uniprot.org/uniprot/E3LT77 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_024433 ^@ http://purl.uniprot.org/uniprot/E3LDZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.|||Membrane http://togogenome.org/gene/31234:GCK72_008051 ^@ http://purl.uniprot.org/uniprot/E3MDQ2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/31234:GCK72_021004 ^@ http://purl.uniprot.org/uniprot/E3MTK1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_020104 ^@ http://purl.uniprot.org/uniprot/E3LHP3 ^@ Similarity ^@ Belongs to the argonaute family. http://togogenome.org/gene/31234:GCK72_002539 ^@ http://purl.uniprot.org/uniprot/E3LVK9 ^@ Similarity ^@ Belongs to the dihydrofolate reductase family. http://togogenome.org/gene/31234:GCK72_004814 ^@ http://purl.uniprot.org/uniprot/E3MZU0 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_004918 ^@ http://purl.uniprot.org/uniprot/E3LGD0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010002 ^@ http://purl.uniprot.org/uniprot/E3MCP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CMC family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_009758 ^@ http://purl.uniprot.org/uniprot/E3LT42 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_012871 ^@ http://purl.uniprot.org/uniprot/E3NC64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.|||Component of a multi-subunit COQ enzyme complex.|||Mitochondrion inner membrane|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/31234:GCK72_010631 ^@ http://purl.uniprot.org/uniprot/E3LYU8 ^@ Similarity ^@ Belongs to the NUF2 family. http://togogenome.org/gene/31234:GCK72_018076 ^@ http://purl.uniprot.org/uniprot/E3LPN6 ^@ Subcellular Location Annotation|||Subunit ^@ Heterodimer of burs and pburs.|||Secreted http://togogenome.org/gene/31234:GCK72_021953 ^@ http://purl.uniprot.org/uniprot/E3MEZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 7B2 family.|||Secreted http://togogenome.org/gene/31234:GCK72_005780 ^@ http://purl.uniprot.org/uniprot/E3MMU2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UQCRQ/QCR8 family.|||Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_008900 ^@ http://purl.uniprot.org/uniprot/E3N6P2 ^@ Similarity ^@ Belongs to the glyoxalase I family. http://togogenome.org/gene/31234:GCK72_013432 ^@ http://purl.uniprot.org/uniprot/E3ND65 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_001229 ^@ http://purl.uniprot.org/uniprot/E3LXM2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. DIPP subfamily. http://togogenome.org/gene/31234:GCK72_007971 ^@ http://purl.uniprot.org/uniprot/E3NLI4 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/31234:GCK72_014752 ^@ http://purl.uniprot.org/uniprot/E3M6N4 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Membrane|||Mitochondrion inner membrane|||The Rieske protein is a high potential 2Fe-2S protein. http://togogenome.org/gene/31234:GCK72_004922 ^@ http://purl.uniprot.org/uniprot/E3LGD5 ^@ Similarity ^@ Belongs to the AP-2 family. http://togogenome.org/gene/31234:GCK72_016728 ^@ http://purl.uniprot.org/uniprot/E3MQD1 ^@ Similarity ^@ Belongs to the calcineurin regulatory subunit family. http://togogenome.org/gene/31234:GCK72_008824 ^@ http://purl.uniprot.org/uniprot/E3M8G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCDC47 family.|||Rough endoplasmic reticulum membrane http://togogenome.org/gene/31234:GCK72_018461 ^@ http://purl.uniprot.org/uniprot/E3LNY9 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/31234:GCK72_013566 ^@ http://purl.uniprot.org/uniprot/E3NQB2 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. http://togogenome.org/gene/31234:GCK72_019656 ^@ http://purl.uniprot.org/uniprot/E3N7G7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_016147 ^@ http://purl.uniprot.org/uniprot/E3NIX7 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/31234:GCK72_024168 ^@ http://purl.uniprot.org/uniprot/E3LER1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_024170 ^@ http://purl.uniprot.org/uniprot/E3LEQ9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_000079 ^@ http://purl.uniprot.org/uniprot/E3N7M7 ^@ Caution|||Cofactor|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/31234:GCK72_014520 ^@ http://purl.uniprot.org/uniprot/E3M6A8 ^@ Similarity ^@ Belongs to the HPF1 family. http://togogenome.org/gene/31234:GCK72_000008 ^@ http://purl.uniprot.org/uniprot/E3MT84 ^@ Similarity ^@ Belongs to the peptidase C15 family. http://togogenome.org/gene/31234:GCK72_000144 ^@ http://purl.uniprot.org/uniprot/E3NJ98 ^@ Similarity ^@ Belongs to the MIF family. http://togogenome.org/gene/31234:GCK72_006334 ^@ http://purl.uniprot.org/uniprot/E3LQW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_014046 ^@ http://purl.uniprot.org/uniprot/E3M7N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_019275 ^@ http://purl.uniprot.org/uniprot/E3LJT9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_009251 ^@ http://purl.uniprot.org/uniprot/E3NFY8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GST superfamily. Pi family.|||Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.|||Homodimer. http://togogenome.org/gene/31234:GCK72_003420 ^@ http://purl.uniprot.org/uniprot/E3N2N5 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_012551 ^@ http://purl.uniprot.org/uniprot/E3N600 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).|||Cytoplasm http://togogenome.org/gene/31234:GCK72_022047 ^@ http://purl.uniprot.org/uniprot/E3NB73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_005823 ^@ http://purl.uniprot.org/uniprot/E3M409 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_022804 ^@ http://purl.uniprot.org/uniprot/E3NCX9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_020122 ^@ http://purl.uniprot.org/uniprot/E3LHQ7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_018345 ^@ http://purl.uniprot.org/uniprot/E3LNL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_003665 ^@ http://purl.uniprot.org/uniprot/E3NB14 ^@ Similarity ^@ Belongs to the WD repeat CDC20/Fizzy family. http://togogenome.org/gene/31234:GCK72_002689 ^@ http://purl.uniprot.org/uniprot/E3LV39 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Tim44 family.|||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_022275 ^@ http://purl.uniprot.org/uniprot/E3M9Z5 ^@ Similarity ^@ Belongs to the sorting nexin family. http://togogenome.org/gene/31234:GCK72_000655 ^@ http://purl.uniprot.org/uniprot/E3M354 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.|||Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.|||Cell projection|||Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.|||Cytoplasm|||Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. http://togogenome.org/gene/31234:GCK72_002319 ^@ http://purl.uniprot.org/uniprot/E3MG65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL43 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_016607 ^@ http://purl.uniprot.org/uniprot/E3MTR8 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_010747 ^@ http://purl.uniprot.org/uniprot/E3LKF8 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_005634 ^@ http://purl.uniprot.org/uniprot/E3LG33 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/31234:GCK72_013369 ^@ http://purl.uniprot.org/uniprot/E3N5L4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_005026 ^@ http://purl.uniprot.org/uniprot/E3LGM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/31234:GCK72_002978 ^@ http://purl.uniprot.org/uniprot/E3N7I9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_014659 ^@ http://purl.uniprot.org/uniprot/E3M6Y3 ^@ Similarity ^@ Belongs to the cytochrome c oxidase subunit 6c family. http://togogenome.org/gene/31234:GCK72_008219 ^@ http://purl.uniprot.org/uniprot/E3MP01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_014159 ^@ http://purl.uniprot.org/uniprot/E3M801 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. http://togogenome.org/gene/31234:GCK72_008859 ^@ http://purl.uniprot.org/uniprot/E3M8D6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SNAPC3/SRD2 family.|||Nucleus|||Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.|||Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. http://togogenome.org/gene/31234:GCK72_014847 ^@ http://purl.uniprot.org/uniprot/E3M532 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_025494 ^@ http://purl.uniprot.org/uniprot/E3MJD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_013630 ^@ http://purl.uniprot.org/uniprot/E3MSE8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS25 family. http://togogenome.org/gene/31234:GCK72_001520 ^@ http://purl.uniprot.org/uniprot/E3N1L9 ^@ Function|||Similarity ^@ Belongs to the ATG12 family.|||Ubiquitin-like protein involved in autophagic vesicle formation. http://togogenome.org/gene/31234:GCK72_000882 ^@ http://purl.uniprot.org/uniprot/E3N4T0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAP-alpha family.|||Endoplasmic reticulum membrane|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins. http://togogenome.org/gene/31234:GCK72_020094 ^@ http://purl.uniprot.org/uniprot/E3LHN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/31234:GCK72_006163 ^@ http://purl.uniprot.org/uniprot/E3LRD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_002499 ^@ http://purl.uniprot.org/uniprot/E3LVP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005822 ^@ http://purl.uniprot.org/uniprot/E3M404 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_025801 ^@ http://purl.uniprot.org/uniprot/E3ME71 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_004105 ^@ http://purl.uniprot.org/uniprot/E3NL63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_020096 ^@ http://purl.uniprot.org/uniprot/E3LHN2 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/31234:GCK72_006753 ^@ http://purl.uniprot.org/uniprot/E3M0W6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Endosome membrane|||Golgi apparatus membrane|||Late endosome membrane|||Membrane|||cis-Golgi network membrane http://togogenome.org/gene/31234:GCK72_005101 ^@ http://purl.uniprot.org/uniprot/E3LGV3 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/31234:GCK72_014619 ^@ http://purl.uniprot.org/uniprot/E3M5Z9 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/31234:GCK72_000664 ^@ http://purl.uniprot.org/uniprot/E3M363 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_019401 ^@ http://purl.uniprot.org/uniprot/E3LKF3 ^@ Similarity ^@ Belongs to the ZC3H14 family. http://togogenome.org/gene/31234:GCK72_008165 ^@ http://purl.uniprot.org/uniprot/E3MNU9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_023088 ^@ http://purl.uniprot.org/uniprot/E3MKL5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_019398 ^@ http://purl.uniprot.org/uniprot/E3LKF0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the clathrin light chain family.|||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.|||Cytoplasmic vesicle membrane|||coated pit http://togogenome.org/gene/31234:GCK72_023568 ^@ http://purl.uniprot.org/uniprot/E3M2U0 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/31234:GCK72_022055 ^@ http://purl.uniprot.org/uniprot/E3NB83 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_019451 ^@ http://purl.uniprot.org/uniprot/E3LKW3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/31234:GCK72_006130 ^@ http://purl.uniprot.org/uniprot/E3M4X0 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_001002 ^@ http://purl.uniprot.org/uniprot/E3LY93 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_013990 ^@ http://purl.uniprot.org/uniprot/E3M7H3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_023505 ^@ http://purl.uniprot.org/uniprot/E3MMQ4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_023577 ^@ http://purl.uniprot.org/uniprot/E3M2U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/31234:GCK72_001929 ^@ http://purl.uniprot.org/uniprot/E3LMM4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/31234:GCK72_017828 ^@ http://purl.uniprot.org/uniprot/E3LUH9 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_000714 ^@ http://purl.uniprot.org/uniprot/E3M3B8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_017122 ^@ http://purl.uniprot.org/uniprot/E3NKL8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_009406 ^@ http://purl.uniprot.org/uniprot/E3LSI5 ^@ Function|||Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.|||E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress. http://togogenome.org/gene/31234:GCK72_019974 ^@ http://purl.uniprot.org/uniprot/E3LHA3 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/31234:GCK72_018870 ^@ http://purl.uniprot.org/uniprot/E3LZV8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_025722 ^@ http://purl.uniprot.org/uniprot/E3MDY4 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_010597 ^@ http://purl.uniprot.org/uniprot/E3LYY3 ^@ Similarity ^@ Belongs to the RCAN family. http://togogenome.org/gene/31234:GCK72_006432 ^@ http://purl.uniprot.org/uniprot/E3LQK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM TET family.|||Nucleus http://togogenome.org/gene/31234:GCK72_001346 ^@ http://purl.uniprot.org/uniprot/E3LX91 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_003810 ^@ http://purl.uniprot.org/uniprot/E3MXF1 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. http://togogenome.org/gene/31234:GCK72_000549 ^@ http://purl.uniprot.org/uniprot/E3M3S4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.|||Belongs to the mitochondrion-specific ribosomal protein mL64 family.|||Mitochondrion|||Nucleus http://togogenome.org/gene/31234:GCK72_004083 ^@ http://purl.uniprot.org/uniprot/E3MZR1 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_024497 ^@ http://purl.uniprot.org/uniprot/E3LDS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UQCRQ/QCR8 family.|||Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_004763 ^@ http://purl.uniprot.org/uniprot/E3MZY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_018196 ^@ http://purl.uniprot.org/uniprot/E3LPZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_013975 ^@ http://purl.uniprot.org/uniprot/E3M7F2 ^@ Similarity ^@ Belongs to the importin alpha family. http://togogenome.org/gene/31234:GCK72_005140 ^@ http://purl.uniprot.org/uniprot/E3LGY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone deacetylase family. HD Type 1 subfamily.|||Nucleus http://togogenome.org/gene/31234:GCK72_005150 ^@ http://purl.uniprot.org/uniprot/E3LGZ9 ^@ Similarity ^@ Belongs to the TTC36 family. http://togogenome.org/gene/31234:GCK72_025277 ^@ http://purl.uniprot.org/uniprot/E3MUE3 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/31234:GCK72_022935 ^@ http://purl.uniprot.org/uniprot/E3MLT5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_020002 ^@ http://purl.uniprot.org/uniprot/E3LHD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_019231 ^@ http://purl.uniprot.org/uniprot/E3LLE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_017357 ^@ http://purl.uniprot.org/uniprot/E3NCI1 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/31234:GCK72_011284 ^@ http://purl.uniprot.org/uniprot/E3NJN1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_009356 ^@ http://purl.uniprot.org/uniprot/E3LSN0 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/31234:GCK72_010106 ^@ http://purl.uniprot.org/uniprot/E3MD05 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RBM8A family.|||Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.|||Cytoplasm|||Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.|||Nucleus|||Nucleus speckle http://togogenome.org/gene/31234:GCK72_014836 ^@ http://purl.uniprot.org/uniprot/E3M515 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||Transcription repressor. http://togogenome.org/gene/31234:GCK72_019611 ^@ http://purl.uniprot.org/uniprot/E3LJP7 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/31234:GCK72_001673 ^@ http://purl.uniprot.org/uniprot/E3LN88 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_009924 ^@ http://purl.uniprot.org/uniprot/E3N9C3 ^@ Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. http://togogenome.org/gene/31234:GCK72_019856 ^@ http://purl.uniprot.org/uniprot/E3LJB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_011981 ^@ http://purl.uniprot.org/uniprot/E3MK76 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/31234:GCK72_005477 ^@ http://purl.uniprot.org/uniprot/E3LFL3 ^@ Function|||Similarity ^@ Belongs to the gamma-BBH/TMLD family.|||Catalyzes the formation of L-carnitine from gamma-butyrobetaine. http://togogenome.org/gene/31234:GCK72_018088 ^@ http://purl.uniprot.org/uniprot/E3LPP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_006629 ^@ http://purl.uniprot.org/uniprot/E3LRJ1 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/31234:GCK72_024553 ^@ http://purl.uniprot.org/uniprot/E3LDL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_000870 ^@ http://purl.uniprot.org/uniprot/E3N4R8 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_020666 ^@ http://purl.uniprot.org/uniprot/E3N100 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_016335 ^@ http://purl.uniprot.org/uniprot/E3N5V0 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/31234:GCK72_014658 ^@ http://purl.uniprot.org/uniprot/E3M6Y4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. http://togogenome.org/gene/31234:GCK72_010147 ^@ http://purl.uniprot.org/uniprot/E3MI11 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/31234:GCK72_006866 ^@ http://purl.uniprot.org/uniprot/E3M1V5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_015872 ^@ http://purl.uniprot.org/uniprot/E3N9P4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_023276 ^@ http://purl.uniprot.org/uniprot/E3MAU7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 13 family.|||Golgi apparatus membrane|||Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.|||Membrane|||The cofactor is mostly bound to the substrate. http://togogenome.org/gene/31234:GCK72_016260 ^@ http://purl.uniprot.org/uniprot/E3NES6 ^@ Similarity ^@ Belongs to the parvin family. http://togogenome.org/gene/31234:GCK72_004243 ^@ http://purl.uniprot.org/uniprot/E3MQ16 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001546 ^@ http://purl.uniprot.org/uniprot/E3N1J7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the eukaryotic-type primase large subunit family.|||Binds 1 [4Fe-4S] cluster.|||DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. http://togogenome.org/gene/31234:GCK72_009459 ^@ http://purl.uniprot.org/uniprot/E3LSD0 ^@ Similarity ^@ Belongs to the NATD1 family. http://togogenome.org/gene/31234:GCK72_021900 ^@ http://purl.uniprot.org/uniprot/E3MF46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_015124 ^@ http://purl.uniprot.org/uniprot/E3M5Y9 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_016449 ^@ http://purl.uniprot.org/uniprot/E3MQV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_009819 ^@ http://purl.uniprot.org/uniprot/E3LSX9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL6 family. http://togogenome.org/gene/31234:GCK72_000705 ^@ http://purl.uniprot.org/uniprot/E3M3B1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. http://togogenome.org/gene/31234:GCK72_014772 ^@ http://purl.uniprot.org/uniprot/E3M6L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_009113 ^@ http://purl.uniprot.org/uniprot/E3MKT1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/31234:GCK72_019365 ^@ http://purl.uniprot.org/uniprot/E3LK86 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/31234:GCK72_009366 ^@ http://purl.uniprot.org/uniprot/E3LSM2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP9 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_016487 ^@ http://purl.uniprot.org/uniprot/E3NLX3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/31234:GCK72_001211 ^@ http://purl.uniprot.org/uniprot/E3LXP0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL4 family. http://togogenome.org/gene/31234:GCK72_013895 ^@ http://purl.uniprot.org/uniprot/E3M779 ^@ Similarity ^@ Belongs to the GST superfamily. Kappa family. http://togogenome.org/gene/31234:GCK72_010705 ^@ http://purl.uniprot.org/uniprot/E3LWZ3 ^@ Subcellular Location Annotation ^@ Recycling endosome http://togogenome.org/gene/31234:GCK72_009972 ^@ http://purl.uniprot.org/uniprot/E3MCK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_005366 ^@ http://purl.uniprot.org/uniprot/E3LFB1 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_001231 ^@ http://purl.uniprot.org/uniprot/E3LXM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin family. SUMO subfamily.|||Nucleus http://togogenome.org/gene/31234:GCK72_024994 ^@ http://purl.uniprot.org/uniprot/E3MRP3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_023428 ^@ http://purl.uniprot.org/uniprot/E3MML0 ^@ Function|||Similarity ^@ Catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a 2 step process.|||In the C-terminal section; belongs to the gob-1 trehalose phosphatase family.|||In the N-terminal section; belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/31234:GCK72_001208 ^@ http://purl.uniprot.org/uniprot/E3LXP3 ^@ Similarity ^@ Belongs to the PTPS family. http://togogenome.org/gene/31234:GCK72_025366 ^@ http://purl.uniprot.org/uniprot/E3MJR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Chromosome|||Nucleus http://togogenome.org/gene/31234:GCK72_008462 ^@ http://purl.uniprot.org/uniprot/E3MY45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS26 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_014398 ^@ http://purl.uniprot.org/uniprot/E3MM03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/31234:GCK72_005482 ^@ http://purl.uniprot.org/uniprot/E3LFM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Common component of the spliceosome and rRNA processing machinery.|||nucleolus http://togogenome.org/gene/31234:GCK72_014502 ^@ http://purl.uniprot.org/uniprot/E3M6C8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/31234:GCK72_009956 ^@ http://purl.uniprot.org/uniprot/E3MCJ2 ^@ Similarity ^@ Belongs to the LRRFIP family. http://togogenome.org/gene/31234:GCK72_005474 ^@ http://purl.uniprot.org/uniprot/E3LFL1 ^@ Function|||Similarity ^@ Belongs to the DPH1/DPH2 family. DPH2 subfamily.|||Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit. http://togogenome.org/gene/31234:GCK72_002222 ^@ http://purl.uniprot.org/uniprot/E3MGD4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_010049 ^@ http://purl.uniprot.org/uniprot/E3MCU3 ^@ Subcellular Location Annotation ^@ Nucleus speckle http://togogenome.org/gene/31234:GCK72_005497 ^@ http://purl.uniprot.org/uniprot/E3NUA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 22 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_014427 ^@ http://purl.uniprot.org/uniprot/E3MLW8 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_012459 ^@ http://purl.uniprot.org/uniprot/E3NHE1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/31234:GCK72_016738 ^@ http://purl.uniprot.org/uniprot/E3MQC1 ^@ Caution|||Cofactor|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/31234:GCK72_011477 ^@ http://purl.uniprot.org/uniprot/E3ND53 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_005242 ^@ http://purl.uniprot.org/uniprot/E3LEY7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.|||Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2-KG as hydrogen acceptor, resulting in the formation of D-2-HG.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_016759 ^@ http://purl.uniprot.org/uniprot/E3MQ96 ^@ Caution|||Cofactor|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/31234:GCK72_008511 ^@ http://purl.uniprot.org/uniprot/E3MXX7 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_009000 ^@ http://purl.uniprot.org/uniprot/E3MWF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_021818 ^@ http://purl.uniprot.org/uniprot/E3NJ00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_005696 ^@ http://purl.uniprot.org/uniprot/E3MN34 ^@ Similarity ^@ Belongs to the TRIAP1/MDM35 family. http://togogenome.org/gene/31234:GCK72_000901 ^@ http://purl.uniprot.org/uniprot/E3MYE4 ^@ Function|||Similarity ^@ Belongs to the ARPC5 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. http://togogenome.org/gene/31234:GCK72_009432 ^@ http://purl.uniprot.org/uniprot/E3LSF7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_002060 ^@ http://purl.uniprot.org/uniprot/E3LM82 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/31234:GCK72_019380 ^@ http://purl.uniprot.org/uniprot/E3LKD1 ^@ Similarity ^@ Belongs to the exportin family. http://togogenome.org/gene/31234:GCK72_009834 ^@ http://purl.uniprot.org/uniprot/E3LSW7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS11 family. http://togogenome.org/gene/31234:GCK72_010690 ^@ http://purl.uniprot.org/uniprot/E3NH09 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_009184 ^@ http://purl.uniprot.org/uniprot/E3ML10 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_018258 ^@ http://purl.uniprot.org/uniprot/E3LQ35 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_025215 ^@ http://purl.uniprot.org/uniprot/E3NDY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_025514 ^@ http://purl.uniprot.org/uniprot/E3MCH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Early endosome membrane|||Endosome|||phagosome|||trans-Golgi network membrane http://togogenome.org/gene/31234:GCK72_008850 ^@ http://purl.uniprot.org/uniprot/E3M8E2 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/31234:GCK72_024018 ^@ http://purl.uniprot.org/uniprot/E3LCQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ACDP family.|||Cell membrane|||Membrane|||Metal transporter. http://togogenome.org/gene/31234:GCK72_023190 ^@ http://purl.uniprot.org/uniprot/E3MKQ8 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_019139 ^@ http://purl.uniprot.org/uniprot/E3LKR4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS27 family. http://togogenome.org/gene/31234:GCK72_018597 ^@ http://purl.uniprot.org/uniprot/E3LPD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the caveolin family.|||Cell membrane|||Golgi apparatus membrane|||Membrane|||caveola http://togogenome.org/gene/31234:GCK72_023740 ^@ http://purl.uniprot.org/uniprot/E3M2S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 3 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_017228 ^@ http://purl.uniprot.org/uniprot/E3NRR9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_023792 ^@ http://purl.uniprot.org/uniprot/E3M220 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_013629 ^@ http://purl.uniprot.org/uniprot/E3MSE9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_001856 ^@ http://purl.uniprot.org/uniprot/E3LMV2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/31234:GCK72_011761 ^@ http://purl.uniprot.org/uniprot/E3MSJ3 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_010575 ^@ http://purl.uniprot.org/uniprot/E3LZ04 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/31234:GCK72_021948 ^@ http://purl.uniprot.org/uniprot/E3MEZ5 ^@ Domain|||Function|||Similarity ^@ Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.|||Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.|||Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine. http://togogenome.org/gene/31234:GCK72_018553 ^@ http://purl.uniprot.org/uniprot/E3LP82 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_014267 ^@ http://purl.uniprot.org/uniprot/E3MSZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_024498 ^@ http://purl.uniprot.org/uniprot/E3LDS3 ^@ Similarity ^@ Belongs to the cAMP-dependent kinase regulatory chain family. http://togogenome.org/gene/31234:GCK72_025847 ^@ http://purl.uniprot.org/uniprot/E3MEB6 ^@ Similarity ^@ Belongs to the cholesterol 7-desaturase family. http://togogenome.org/gene/31234:GCK72_005461 ^@ http://purl.uniprot.org/uniprot/E3LFJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Nup35 family.|||nuclear pore complex http://togogenome.org/gene/31234:GCK72_024270 ^@ http://purl.uniprot.org/uniprot/E3LEG3 ^@ Similarity ^@ Belongs to the Rho GDI family. http://togogenome.org/gene/31234:GCK72_014603 ^@ http://purl.uniprot.org/uniprot/E3M615 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC41A transporter family.|||Membrane http://togogenome.org/gene/31234:GCK72_003601 ^@ http://purl.uniprot.org/uniprot/E3M905 ^@ Similarity ^@ Belongs to the WD repeat EIPR1 family. http://togogenome.org/gene/31234:GCK72_001908 ^@ http://purl.uniprot.org/uniprot/E3LMP7 ^@ Similarity ^@ Belongs to the proteasome subunit S5A family. http://togogenome.org/gene/31234:GCK72_008732 ^@ http://purl.uniprot.org/uniprot/E3M875 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/31234:GCK72_009866 ^@ http://purl.uniprot.org/uniprot/E3LST8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_014065 ^@ http://purl.uniprot.org/uniprot/E3M7Q3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_006347 ^@ http://purl.uniprot.org/uniprot/E3LQU8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SSU72 phosphatase family.|||Nucleus|||Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. http://togogenome.org/gene/31234:GCK72_006293 ^@ http://purl.uniprot.org/uniprot/E3LR05 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/31234:GCK72_018044 ^@ http://purl.uniprot.org/uniprot/E3LPK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TDE1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_018803 ^@ http://purl.uniprot.org/uniprot/E3LZN9 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/31234:GCK72_009583 ^@ http://purl.uniprot.org/uniprot/E3LS00 ^@ Similarity ^@ Belongs to the Tango6 family. http://togogenome.org/gene/31234:GCK72_001716 ^@ http://purl.uniprot.org/uniprot/E3LN44 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the NDC80/HEC1 family.|||Component of the NDC80 complex.|||Nucleus|||kinetochore http://togogenome.org/gene/31234:GCK72_001438 ^@ http://purl.uniprot.org/uniprot/E3MFE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS8 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/31234:GCK72_008522 ^@ http://purl.uniprot.org/uniprot/E3NHF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_010095 ^@ http://purl.uniprot.org/uniprot/E3MCZ2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_023722 ^@ http://purl.uniprot.org/uniprot/E3M2P7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010104 ^@ http://purl.uniprot.org/uniprot/E3MD03 ^@ Similarity ^@ Belongs to the GPATCH1 family. http://togogenome.org/gene/31234:GCK72_000327 ^@ http://purl.uniprot.org/uniprot/E3MX86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the USE1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_013431 ^@ http://purl.uniprot.org/uniprot/E3ND64 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_012869 ^@ http://purl.uniprot.org/uniprot/E3NC65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I LYR family.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_023730 ^@ http://purl.uniprot.org/uniprot/E3M2Q6 ^@ Similarity ^@ Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. http://togogenome.org/gene/31234:GCK72_017805 ^@ http://purl.uniprot.org/uniprot/E3LUF5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001706 ^@ http://purl.uniprot.org/uniprot/E3LN55 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_007196 ^@ http://purl.uniprot.org/uniprot/E3MJ56 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_015691 ^@ http://purl.uniprot.org/uniprot/E3N905 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_016263 ^@ http://purl.uniprot.org/uniprot/E3NES9 ^@ Similarity ^@ Belongs to the SPARC family. http://togogenome.org/gene/31234:GCK72_016508 ^@ http://purl.uniprot.org/uniprot/E3N790 ^@ Similarity ^@ Belongs to the WD repeat PRL1/PRL2 family. http://togogenome.org/gene/31234:GCK72_023136 ^@ http://purl.uniprot.org/uniprot/E3MKG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Membrane http://togogenome.org/gene/31234:GCK72_016605 ^@ http://purl.uniprot.org/uniprot/E3MTR9 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_010806 ^@ http://purl.uniprot.org/uniprot/E3LWN8 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family. http://togogenome.org/gene/31234:GCK72_009775 ^@ http://purl.uniprot.org/uniprot/E3LT25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_016258 ^@ http://purl.uniprot.org/uniprot/E3NES4 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_001393 ^@ http://purl.uniprot.org/uniprot/E3MFK1 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/31234:GCK72_024850 ^@ http://purl.uniprot.org/uniprot/E3LCD1 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_019979 ^@ http://purl.uniprot.org/uniprot/E3LHA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_023774 ^@ http://purl.uniprot.org/uniprot/E3M2X2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acid sphingomyelinase family.|||Binds 2 Zn(2+) ions per subunit.|||Converts sphingomyelin to ceramide.|||Secreted http://togogenome.org/gene/31234:GCK72_018178 ^@ http://purl.uniprot.org/uniprot/E3LPY4 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_010601 ^@ http://purl.uniprot.org/uniprot/E3LYX8 ^@ Function|||Similarity ^@ Belongs to the ATG12 family.|||Ubiquitin-like protein involved in autophagic vesicle formation. http://togogenome.org/gene/31234:GCK72_008135 ^@ http://purl.uniprot.org/uniprot/E3MDG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty-acid and retinol-binding protein (FARBP) family.|||Secreted http://togogenome.org/gene/31234:GCK72_013779 ^@ http://purl.uniprot.org/uniprot/E3N3U9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the proteasome subunit S2 family.|||Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.|||Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).|||Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. http://togogenome.org/gene/31234:GCK72_015031 ^@ http://purl.uniprot.org/uniprot/E3M5N8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Vesicular transporter family.|||Membrane http://togogenome.org/gene/31234:GCK72_014234 ^@ http://purl.uniprot.org/uniprot/E3MSW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/31234:GCK72_009479 ^@ http://purl.uniprot.org/uniprot/E3LSA9 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/31234:GCK72_018866 ^@ http://purl.uniprot.org/uniprot/E3LZV5 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/31234:GCK72_014433 ^@ http://purl.uniprot.org/uniprot/E3MLW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transcriptional coactivator PC4 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_000335 ^@ http://purl.uniprot.org/uniprot/E3MX94 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/31234:GCK72_018448 ^@ http://purl.uniprot.org/uniprot/E3LNX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_015023 ^@ http://purl.uniprot.org/uniprot/E3M5M9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/31234:GCK72_009947 ^@ http://purl.uniprot.org/uniprot/E3MCI4 ^@ Similarity ^@ Belongs to the proteasome subunit S9 family. http://togogenome.org/gene/31234:GCK72_009007 ^@ http://purl.uniprot.org/uniprot/E3MWG3 ^@ Similarity ^@ Belongs to the TEL2 family. http://togogenome.org/gene/31234:GCK72_019790 ^@ http://purl.uniprot.org/uniprot/E3LIZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_013541 ^@ http://purl.uniprot.org/uniprot/E3MR32 ^@ Similarity ^@ Belongs to the histone deacetylase family. HD type 2 subfamily. http://togogenome.org/gene/31234:GCK72_009364 ^@ http://purl.uniprot.org/uniprot/E3LSM3 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/31234:GCK72_018739 ^@ http://purl.uniprot.org/uniprot/E3M0P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 22 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_018709 ^@ http://purl.uniprot.org/uniprot/E3M0L3 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/31234:GCK72_000160 ^@ http://purl.uniprot.org/uniprot/E3NJ90 ^@ Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/31234:GCK72_025810 ^@ http://purl.uniprot.org/uniprot/E3ME81 ^@ Similarity ^@ Belongs to the CCDC93 family. http://togogenome.org/gene/31234:GCK72_006732 ^@ http://purl.uniprot.org/uniprot/E3M0Z3 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srg family. http://togogenome.org/gene/31234:GCK72_022287 ^@ http://purl.uniprot.org/uniprot/E3M9Y2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the UDPGP type 1 family.|||Homooctamer.|||UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. http://togogenome.org/gene/31234:GCK72_007977 ^@ http://purl.uniprot.org/uniprot/E3N371 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_021893 ^@ http://purl.uniprot.org/uniprot/E3MF55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_018610 ^@ http://purl.uniprot.org/uniprot/E3M098 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMO family.|||Endoplasmic reticulum membrane|||Membrane|||Microsome membrane http://togogenome.org/gene/31234:GCK72_012105 ^@ http://purl.uniprot.org/uniprot/E3MES1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FARP (FMRFamide related peptide) family.|||Secreted http://togogenome.org/gene/31234:GCK72_009476 ^@ http://purl.uniprot.org/uniprot/E3LSB2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/31234:GCK72_018454 ^@ http://purl.uniprot.org/uniprot/E3LNY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_020012 ^@ http://purl.uniprot.org/uniprot/E3LHE4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_009269 ^@ http://purl.uniprot.org/uniprot/E3N0A3 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/31234:GCK72_005005 ^@ http://purl.uniprot.org/uniprot/E3LGL1 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_005262 ^@ http://purl.uniprot.org/uniprot/E3LF07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_019162 ^@ http://purl.uniprot.org/uniprot/E3LKV2 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. http://togogenome.org/gene/31234:GCK72_014371 ^@ http://purl.uniprot.org/uniprot/E3MM32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COPG family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/31234:GCK72_025121 ^@ http://purl.uniprot.org/uniprot/E3MZG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF7 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_000376 ^@ http://purl.uniprot.org/uniprot/E3NFE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CBF-beta family.|||Nucleus http://togogenome.org/gene/31234:GCK72_018736 ^@ http://purl.uniprot.org/uniprot/E3M0P3 ^@ Similarity ^@ Belongs to the glycine N-acyltransferase family. http://togogenome.org/gene/31234:GCK72_017636 ^@ http://purl.uniprot.org/uniprot/E3LTX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_024807 ^@ http://purl.uniprot.org/uniprot/E3LCM7 ^@ Similarity ^@ Belongs to the apyrase family. http://togogenome.org/gene/31234:GCK72_001133 ^@ http://purl.uniprot.org/uniprot/E3LXX1 ^@ Function|||Subcellular Location Annotation ^@ General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.|||Golgi apparatus|||Membrane|||Mitochondrion http://togogenome.org/gene/31234:GCK72_023296 ^@ http://purl.uniprot.org/uniprot/E3MAW9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GOSR2 family.|||Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.|||Membrane http://togogenome.org/gene/31234:GCK72_004237 ^@ http://purl.uniprot.org/uniprot/E3MQ11 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_003417 ^@ http://purl.uniprot.org/uniprot/E3N2N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-CoA oxidase family.|||Peroxisome http://togogenome.org/gene/31234:GCK72_017637 ^@ http://purl.uniprot.org/uniprot/E3LTX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_012733 ^@ http://purl.uniprot.org/uniprot/E3N2D0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_017453 ^@ http://purl.uniprot.org/uniprot/E3MNB6 ^@ Similarity ^@ Belongs to the FAM50 family. http://togogenome.org/gene/31234:GCK72_006370 ^@ http://purl.uniprot.org/uniprot/E3LQR9 ^@ Similarity ^@ Belongs to the proteasome subunit p27 family. http://togogenome.org/gene/31234:GCK72_001909 ^@ http://purl.uniprot.org/uniprot/E3LMP6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family. http://togogenome.org/gene/31234:GCK72_021992 ^@ http://purl.uniprot.org/uniprot/E3MEV5 ^@ Similarity ^@ Belongs to the DAMOX/DASOX family. http://togogenome.org/gene/31234:GCK72_014511 ^@ http://purl.uniprot.org/uniprot/A0A2P4W6K8|||http://purl.uniprot.org/uniprot/P45436 ^@ Activity Regulation|||Caution|||Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a cysteine protease in controlling programmed cell death (apoptosis) by proteolytically activating or inactivating a wide range of substrates. Component of the egl-1, ced-9, ced-4 and ced-3 apoptotic signaling cascade required for the initiation of programmed cell death in cells fated to die during embryonic and postembryonic development. During oogenesis, required for germline apoptosis downstream of ced-9 and ced-4 but independently of egl-1. By cleaving and activating ced-8, promotes phosphatidylserine exposure on the surface of apoptotic cells; phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. By cleaving and converting dcr-1 into a deoxyribonuclease (DNase), promotes apoptotic chromosomal DNA fragmentation. By cleaving mitochondrial fission protein drp-1, may regulate the removal of mitochondria during apoptosis. During germline apoptosis, cleaves translation initiation factor ifg-1 (isoform p170) promoting cap-independent translation. During male tail morphogenesis, promotes apoptosis of the tail-spike cell downstream of ced-4 but independently of egl-1 and ced-9. By cleaving cnt-1, prevents the activation of the prosurvival akt-1/2 signaling pathway and thus promotes apoptosis. Downstream of ced-4, may play a role in sex-specific cell apoptosis by cleaving sex-determining protein fem-1. May regulate germline apoptosis in response to DNA damage, probably downstream of let-60/ras and mpk-1 pathway. Cleaves ced-9 in vitro. Cleaves csp-2 isoform b resulting in the removal of the propeptide and the generation of csp-2 subunit p31 in vitro. Independently of its apoptotic role has additional functions. Probably by cleaving and thereby activating actin-severing protein gsnl-1, required for the elimination of transient presynaptic components during larval development downstream of egl-1, ced-9 and ced-4 pathway. Together with ain-1, a component of the miRNA-induced-silencing complex (miRISC), regulates temporal cell fate patterning during larval development. Acts in cell fate patterning by cleaving heterochronic protein lin-28, likely promoting its degradation. Also cleaves heterochronic protein lin-14 and exonuclease disl-2 in vitro. Downstream of calreticulin crt-1 and ced-4 and independently of egl-1 and ced-9, plays a role in the initial steps of axonal regrowth following axotomy. Cleaves 14-3-3-like protein ftt-2, tubulin tbb-2 and calreticulin crt-1 in vitro. Plays also a role in resistance to S.typhimurium-mediated infection.|||Autocatalytic cleavage removes the propeptide and generates the catalytic subunit p17 and two non-catalytic subunits p15 and p13; autoproteolysis is induced by ced-4 oligomer. Cleaved by caspase csp-1 probably at Asp-146 and Asp-376.|||Belongs to the peptidase C14A family.|||Cytoplasm|||Mitochondrion|||Nucleus membrane|||Octameric ced-4 activates zymogen autoprocessing and enhances activity of processed ced-3. Zymogen autoactivation is inhibited by csp-3. csp-3 has no effect on active ced-3. Zymogen autoactivation is inhibited by csp-2. Inhibited by cysteine protease inhibitor iodoacetic acid (CH3COOI). Inhibited by benzyloxycarbonyl-DEVD-fluoro-methyl ketone (zDEVD-fmk). Inhibited by benzyloxycarbonyl-VAD-fluoro-methyl ketone (zVAD-fmk). Not inhibited by N-[N-(L-3-transcarboxirane-2-carbonyl)-leucyl]-agmatine (E-64) or by the serine and cysteine protease inhibitor L-1-chloro-3-[4-to-osylamido]-7-amino-2-heptanone (TLCK).|||Perikaryon|||Synapse|||The CARD domain is involved in ced-4 binding.|||The active form is probably a heterodimer of the p17 subunit with either the p15 or p13 subunit which are all derived from the precursor by autocatalysis. Interacts with octameric ced-4 (two ced-3 zymogens per one ced-4 octamer); the interaction causes the autoproteolytic cleavage and activation of ced-3. Processed ced-3 also interacts with ced-4 octamer to form a stable holoenzyme. Interacts (via large subunit p17) with csp-3; the interaction prevents ced-3 autoactivation and delays ced-4-induced ced-3 processing. Interacts (via large subunit p17 or small subunit p13 or p15) with csp-2; the interaction inhibits ced-3 autoactivation. Interacts (via propeptide) with nucleoporin npp-14; the interaction tethers ced-3 to the nuclear membrane and prevents its autoprocessing in absence of ced-4. Interacts with dct-1. May form a complex composed of ced-3, ced-4 and mac-1.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||perinuclear region http://togogenome.org/gene/31234:GCK72_001266 ^@ http://purl.uniprot.org/uniprot/E3LXH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the telombin family.|||Nucleus|||telomere http://togogenome.org/gene/31234:GCK72_000883 ^@ http://purl.uniprot.org/uniprot/E3N4T1 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/31234:GCK72_023814 ^@ http://purl.uniprot.org/uniprot/E3M265 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/31234:GCK72_015082 ^@ http://purl.uniprot.org/uniprot/E3M5V0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010158 ^@ http://purl.uniprot.org/uniprot/E3MI24 ^@ Similarity ^@ Belongs to the PITHD1 family. http://togogenome.org/gene/31234:GCK72_019306 ^@ http://purl.uniprot.org/uniprot/E3LJX7 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/31234:GCK72_006123 ^@ http://purl.uniprot.org/uniprot/E3M4W3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/31234:GCK72_010964 ^@ http://purl.uniprot.org/uniprot/E3LW65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PER33/POM33 family.|||Membrane http://togogenome.org/gene/31234:GCK72_004809 ^@ http://purl.uniprot.org/uniprot/E3MZU5 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_009286 ^@ http://purl.uniprot.org/uniprot/E3N088 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis. http://togogenome.org/gene/31234:GCK72_010849 ^@ http://purl.uniprot.org/uniprot/E3LWJ0 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_009917 ^@ http://purl.uniprot.org/uniprot/E3N9B6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_003550 ^@ http://purl.uniprot.org/uniprot/E3M8W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane http://togogenome.org/gene/31234:GCK72_003596 ^@ http://purl.uniprot.org/uniprot/E3M8Z9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL31 family. http://togogenome.org/gene/31234:GCK72_020737 ^@ http://purl.uniprot.org/uniprot/E3MB82 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May be involved in iron transport and iron homeostasis.|||Membrane http://togogenome.org/gene/31234:GCK72_001914 ^@ http://purl.uniprot.org/uniprot/E3LMP0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_009139 ^@ http://purl.uniprot.org/uniprot/E3MKV0 ^@ Similarity ^@ Belongs to the peptidase S28 family. http://togogenome.org/gene/31234:GCK72_006421 ^@ http://purl.uniprot.org/uniprot/E3LQL2 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/31234:GCK72_023382 ^@ http://purl.uniprot.org/uniprot/E3MB54 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_019881 ^@ http://purl.uniprot.org/uniprot/E3LJD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_005379 ^@ http://purl.uniprot.org/uniprot/E3LFC3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_018141 ^@ http://purl.uniprot.org/uniprot/E3LPV2 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 38 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/31234:GCK72_004779 ^@ http://purl.uniprot.org/uniprot/E3MZX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_024713 ^@ http://purl.uniprot.org/uniprot/E3LD47 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_002919 ^@ http://purl.uniprot.org/uniprot/E3N969 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM53 family.|||Membrane|||Nucleus outer membrane http://togogenome.org/gene/31234:GCK72_000533 ^@ http://purl.uniprot.org/uniprot/E3M3Q6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_000880 ^@ http://purl.uniprot.org/uniprot/E3N4S8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ARTD/PARP family.|||Nucleus http://togogenome.org/gene/31234:GCK72_006068 ^@ http://purl.uniprot.org/uniprot/E3M4R0 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/31234:GCK72_017740 ^@ http://purl.uniprot.org/uniprot/Q1PSW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_005391 ^@ http://purl.uniprot.org/uniprot/E3LFD5 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/31234:GCK72_025724 ^@ http://purl.uniprot.org/uniprot/E3MDY6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_016242 ^@ http://purl.uniprot.org/uniprot/E3NEU4 ^@ Similarity ^@ Belongs to the DCP1 family. http://togogenome.org/gene/31234:GCK72_015527 ^@ http://purl.uniprot.org/uniprot/E3NCA9 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_025342 ^@ http://purl.uniprot.org/uniprot/E3MJU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 27 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_018600 ^@ http://purl.uniprot.org/uniprot/E3M087 ^@ Similarity ^@ Belongs to the CIA30 family. http://togogenome.org/gene/31234:GCK72_009163 ^@ http://purl.uniprot.org/uniprot/E3MKY2 ^@ Similarity ^@ Belongs to the nucleoporin Nup133 family. http://togogenome.org/gene/31234:GCK72_008715 ^@ http://purl.uniprot.org/uniprot/E3M890 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.|||Endoplasmic reticulum membrane|||Required for N-linked oligosaccharide assembly. http://togogenome.org/gene/31234:GCK72_007858 ^@ http://purl.uniprot.org/uniprot/E3N288 ^@ Similarity ^@ Belongs to the plant self-incompatibility (S1) protein family. http://togogenome.org/gene/31234:GCK72_013295 ^@ http://purl.uniprot.org/uniprot/E3MRI4 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_022160 ^@ http://purl.uniprot.org/uniprot/E3MAB9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_018721 ^@ http://purl.uniprot.org/uniprot/E3M0M7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_025129 ^@ http://purl.uniprot.org/uniprot/E3MZF4 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_005165 ^@ http://purl.uniprot.org/uniprot/E3LH14 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_020109 ^@ http://purl.uniprot.org/uniprot/E3LHP6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_008038 ^@ http://purl.uniprot.org/uniprot/E3MDR9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC1 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_017787 ^@ http://purl.uniprot.org/uniprot/E3LUD7 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. HMG-CoA synthase family.|||Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. http://togogenome.org/gene/31234:GCK72_014655 ^@ http://purl.uniprot.org/uniprot/E3M6Y7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_009954 ^@ http://purl.uniprot.org/uniprot/E3MCJ1 ^@ Similarity ^@ Belongs to the DEAD box helicase family. eIF4A subfamily. http://togogenome.org/gene/31234:GCK72_005319 ^@ http://purl.uniprot.org/uniprot/E3LF66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFIIE beta subunit family.|||Nucleus|||Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.|||Tetramer of two alpha and two beta chains. http://togogenome.org/gene/31234:GCK72_008463 ^@ http://purl.uniprot.org/uniprot/E3MY44 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. http://togogenome.org/gene/31234:GCK72_001426 ^@ http://purl.uniprot.org/uniprot/E3MFF5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_006074 ^@ http://purl.uniprot.org/uniprot/E3M4R6 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily. http://togogenome.org/gene/31234:GCK72_011550 ^@ http://purl.uniprot.org/uniprot/E3MIT4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/31234:GCK72_013735 ^@ http://purl.uniprot.org/uniprot/E3N401 ^@ Similarity ^@ Belongs to the helicase family. RLR subfamily. http://togogenome.org/gene/31234:GCK72_001421 ^@ http://purl.uniprot.org/uniprot/E3MFG0 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_013459 ^@ http://purl.uniprot.org/uniprot/E3ND91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA5 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_013151 ^@ http://purl.uniprot.org/uniprot/E3NKC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_000090 ^@ http://purl.uniprot.org/uniprot/E3NHT9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB7 subunit family.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/31234:GCK72_009946 ^@ http://purl.uniprot.org/uniprot/E3MCI3 ^@ Function|||Similarity ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). http://togogenome.org/gene/31234:GCK72_008186 ^@ http://purl.uniprot.org/uniprot/E3MNS7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_015736 ^@ http://purl.uniprot.org/uniprot/E3MXT2 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/31234:GCK72_003717 ^@ http://purl.uniprot.org/uniprot/E3N2T5 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/31234:GCK72_001050 ^@ http://purl.uniprot.org/uniprot/E3LY52 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/31234:GCK72_009534 ^@ http://purl.uniprot.org/uniprot/E3LS50 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/31234:GCK72_016185 ^@ http://purl.uniprot.org/uniprot/E3NBR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_005746 ^@ http://purl.uniprot.org/uniprot/E3MMY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IWR1/SLC7A6OS family.|||Cytoplasm|||Directs RNA polymerase II nuclear import.|||Nucleus http://togogenome.org/gene/31234:GCK72_000182 ^@ http://purl.uniprot.org/uniprot/E3NKQ7 ^@ Function|||Subunit ^@ Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.|||Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site. http://togogenome.org/gene/31234:GCK72_023351 ^@ http://purl.uniprot.org/uniprot/E3MB20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_025654 ^@ http://purl.uniprot.org/uniprot/E3MC41 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_021316 ^@ http://purl.uniprot.org/uniprot/E3N8L9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_015772 ^@ http://purl.uniprot.org/uniprot/E3NJ19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_018158 ^@ http://purl.uniprot.org/uniprot/E3LPW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_018607 ^@ http://purl.uniprot.org/uniprot/E3M095 ^@ Similarity ^@ Belongs to the TBCB family. http://togogenome.org/gene/31234:GCK72_014036 ^@ http://purl.uniprot.org/uniprot/E3M7M0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family.|||In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.|||In the N-terminal section; belongs to the GART family. http://togogenome.org/gene/31234:GCK72_020447 ^@ http://purl.uniprot.org/uniprot/E3LIT7 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/31234:GCK72_001513 ^@ http://purl.uniprot.org/uniprot/E3N1M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the jagunal family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_005304 ^@ http://purl.uniprot.org/uniprot/E3LF52 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nucleoporin Nup84/Nup107 family.|||Functions as a component of the nuclear pore complex (NPC).|||Nucleus membrane|||Part of the nuclear pore complex (NPC).|||nuclear pore complex http://togogenome.org/gene/31234:GCK72_013716 ^@ http://purl.uniprot.org/uniprot/E3N421 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/31234:GCK72_013639 ^@ http://purl.uniprot.org/uniprot/E3MSD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/31234:GCK72_006104 ^@ http://purl.uniprot.org/uniprot/E3M4U6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EBP2 family.|||Required for the processing of the 27S pre-rRNA.|||nucleolus http://togogenome.org/gene/31234:GCK72_004943 ^@ http://purl.uniprot.org/uniprot/E3LGF7 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/31234:GCK72_000668 ^@ http://purl.uniprot.org/uniprot/E3LKS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_014580 ^@ http://purl.uniprot.org/uniprot/E3M645 ^@ Similarity ^@ Belongs to the RNase Z family. http://togogenome.org/gene/31234:GCK72_016435 ^@ http://purl.uniprot.org/uniprot/E3MQV0 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I family. http://togogenome.org/gene/31234:GCK72_006044 ^@ http://purl.uniprot.org/uniprot/E3M4N7 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_007864 ^@ http://purl.uniprot.org/uniprot/E3N276 ^@ Similarity ^@ Belongs to the plant self-incompatibility (S1) protein family. http://togogenome.org/gene/31234:GCK72_002232 ^@ http://purl.uniprot.org/uniprot/E3MGE5 ^@ Similarity|||Subunit ^@ Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.|||Heterodimer of a catalytic heavy chain and a regulatory light chain. http://togogenome.org/gene/31234:GCK72_003536 ^@ http://purl.uniprot.org/uniprot/E3M8U4 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/31234:GCK72_011429 ^@ http://purl.uniprot.org/uniprot/E3MW78 ^@ Caution|||Similarity ^@ Belongs to the peptidase C2 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_002602 ^@ http://purl.uniprot.org/uniprot/E3LVD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_013340 ^@ http://purl.uniprot.org/uniprot/E3NMC8 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_016570 ^@ http://purl.uniprot.org/uniprot/E3MTV3 ^@ Similarity ^@ Belongs to the TMEM70 family. http://togogenome.org/gene/31234:GCK72_005441 ^@ http://purl.uniprot.org/uniprot/E3LFH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ORC2 family.|||Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.|||Component of the origin recognition complex (ORC).|||Nucleus http://togogenome.org/gene/31234:GCK72_014857 ^@ http://purl.uniprot.org/uniprot/E3M544 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/31234:GCK72_009037 ^@ http://purl.uniprot.org/uniprot/E3N6Q0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Membrane http://togogenome.org/gene/31234:GCK72_006627 ^@ http://purl.uniprot.org/uniprot/E3LRJ3 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_012596 ^@ http://purl.uniprot.org/uniprot/E3N7U2 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_024399 ^@ http://purl.uniprot.org/uniprot/E3LE33 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.|||Belongs to the sulfotransferase 6 family.|||Membrane http://togogenome.org/gene/31234:GCK72_025598 ^@ http://purl.uniprot.org/uniprot/E3MC95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_012414 ^@ http://purl.uniprot.org/uniprot/E3NI18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Chromosome|||Nucleus http://togogenome.org/gene/31234:GCK72_013912 ^@ http://purl.uniprot.org/uniprot/E3M792 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_015783 ^@ http://purl.uniprot.org/uniprot/E3NGT8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_025727 ^@ http://purl.uniprot.org/uniprot/E3MDZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/31234:GCK72_001254 ^@ http://purl.uniprot.org/uniprot/E3LXI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM39 family.|||Membrane http://togogenome.org/gene/31234:GCK72_020119 ^@ http://purl.uniprot.org/uniprot/E3LHQ4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_006206 ^@ http://purl.uniprot.org/uniprot/E3LR99 ^@ Similarity ^@ Belongs to the GSKIP family. http://togogenome.org/gene/31234:GCK72_014125 ^@ http://purl.uniprot.org/uniprot/E3M7W5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_002814 ^@ http://purl.uniprot.org/uniprot/E3MVV5 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_010954 ^@ http://purl.uniprot.org/uniprot/E3LW74 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/31234:GCK72_022015 ^@ http://purl.uniprot.org/uniprot/E3MET3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GINS4/SLD5 family.|||Nucleus|||The GINS complex plays an essential role in the initiation of DNA replication. http://togogenome.org/gene/31234:GCK72_001260 ^@ http://purl.uniprot.org/uniprot/E3LXI2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017410 ^@ http://purl.uniprot.org/uniprot/E3MN60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Chromosome|||Nucleus http://togogenome.org/gene/31234:GCK72_001917 ^@ http://purl.uniprot.org/uniprot/E3LMN9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_005384 ^@ http://purl.uniprot.org/uniprot/E3LFC8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the proteasome subunit S11 family.|||Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.|||Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. http://togogenome.org/gene/31234:GCK72_009334 ^@ http://purl.uniprot.org/uniprot/E3N044 ^@ Similarity ^@ Belongs to the peroxin-19 family. http://togogenome.org/gene/31234:GCK72_022166 ^@ http://purl.uniprot.org/uniprot/E3MAB4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_024411 ^@ http://purl.uniprot.org/uniprot/E3LE21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Membrane http://togogenome.org/gene/31234:GCK72_002809 ^@ http://purl.uniprot.org/uniprot/E3MVW0 ^@ Similarity ^@ Belongs to the NUP210 family. http://togogenome.org/gene/31234:GCK72_014848 ^@ http://purl.uniprot.org/uniprot/E3M533 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_014916 ^@ http://purl.uniprot.org/uniprot/E3M5A5 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. http://togogenome.org/gene/31234:GCK72_006064 ^@ http://purl.uniprot.org/uniprot/E3M4Q7 ^@ Similarity ^@ Belongs to the insulin family. http://togogenome.org/gene/31234:GCK72_024603 ^@ http://purl.uniprot.org/uniprot/E3LDG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/31234:GCK72_007713 ^@ http://purl.uniprot.org/uniprot/E3M9K0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_009431 ^@ http://purl.uniprot.org/uniprot/E3LSF8 ^@ Function|||Similarity ^@ Belongs to the AB hydrolase superfamily.|||Demethylates proteins that have been reversibly carboxymethylated. http://togogenome.org/gene/31234:GCK72_009293 ^@ http://purl.uniprot.org/uniprot/E3N085 ^@ Similarity ^@ Belongs to the complex I LYR family. http://togogenome.org/gene/31234:GCK72_014793 ^@ http://purl.uniprot.org/uniprot/E3M6J9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/31234:GCK72_009650 ^@ http://purl.uniprot.org/uniprot/E3LRT7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20A family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/31234:GCK72_008371 ^@ http://purl.uniprot.org/uniprot/E3MFP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.|||Cytoplasm|||Membrane http://togogenome.org/gene/31234:GCK72_017924 ^@ http://purl.uniprot.org/uniprot/E3LUT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_007995 ^@ http://purl.uniprot.org/uniprot/E3MDD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG2 family.|||Cytoplasmic vesicle|||Endoplasmic reticulum membrane|||Nucleus envelope|||Nucleus inner membrane|||Nucleus outer membrane|||Vesicle http://togogenome.org/gene/31234:GCK72_006417 ^@ http://purl.uniprot.org/uniprot/E3LQL7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/31234:GCK72_017364 ^@ http://purl.uniprot.org/uniprot/E3NCJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Ras family.|||Endosome membrane|||Recycling endosome membrane http://togogenome.org/gene/31234:GCK72_016573 ^@ http://purl.uniprot.org/uniprot/E3MTV0 ^@ Similarity ^@ Belongs to the FAD-binding oxidoreductase/transferase type 4 family. http://togogenome.org/gene/31234:GCK72_011944 ^@ http://purl.uniprot.org/uniprot/E3MKB7 ^@ Similarity ^@ Belongs to the fructosamine kinase family. http://togogenome.org/gene/31234:GCK72_019160 ^@ http://purl.uniprot.org/uniprot/E3LKV0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/31234:GCK72_022022 ^@ http://purl.uniprot.org/uniprot/E3MES5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_013560 ^@ http://purl.uniprot.org/uniprot/E3MR13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_005113 ^@ http://purl.uniprot.org/uniprot/E3LGW4 ^@ Similarity ^@ Belongs to the glycerophosphoryl diester phosphodiesterase family. http://togogenome.org/gene/31234:GCK72_003805 ^@ http://purl.uniprot.org/uniprot/E3MXE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad21 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_023214 ^@ http://purl.uniprot.org/uniprot/E3MAN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_015119 ^@ http://purl.uniprot.org/uniprot/E3NTH2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CWC16 family. YJU2 subfamily.|||Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.|||Nucleus|||Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. http://togogenome.org/gene/31234:GCK72_014947 ^@ http://purl.uniprot.org/uniprot/E3M5E3 ^@ Caution|||Similarity ^@ Belongs to the globin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_025180 ^@ http://purl.uniprot.org/uniprot/E3MZA5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.|||Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP. http://togogenome.org/gene/31234:GCK72_002409 ^@ http://purl.uniprot.org/uniprot/E3LVY9 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL10 family.|||Ribosomal protein P0 is the functional equivalent of E.coli protein L10. http://togogenome.org/gene/31234:GCK72_022182 ^@ http://purl.uniprot.org/uniprot/E3MA97 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_023253 ^@ http://purl.uniprot.org/uniprot/E3MAS5 ^@ Similarity ^@ Belongs to the eukaryotic NMN adenylyltransferase family. http://togogenome.org/gene/31234:GCK72_000208 ^@ http://purl.uniprot.org/uniprot/E3NGX9 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_010346 ^@ http://purl.uniprot.org/uniprot/E3LYJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF9 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_011684 ^@ http://purl.uniprot.org/uniprot/E3NAJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_008847 ^@ http://purl.uniprot.org/uniprot/E3M8E5 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/31234:GCK72_014590 ^@ http://purl.uniprot.org/uniprot/E3NX57 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_023976 ^@ http://purl.uniprot.org/uniprot/E3LD03 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase H subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Subunit H is essential for V-ATPase activity, but not for the assembly of the complex.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/31234:GCK72_001388 ^@ http://purl.uniprot.org/uniprot/E3MFK5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the helicase family. PIF1 subfamily.|||DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.|||Mitochondrion|||Monomer.|||Nucleus http://togogenome.org/gene/31234:GCK72_010635 ^@ http://purl.uniprot.org/uniprot/E3LYU3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 15 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_025421 ^@ http://purl.uniprot.org/uniprot/E3MJL0 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_004808 ^@ http://purl.uniprot.org/uniprot/E3MZU6 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_009787 ^@ http://purl.uniprot.org/uniprot/E3LT12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TM2 family.|||Membrane http://togogenome.org/gene/31234:GCK72_002155 ^@ http://purl.uniprot.org/uniprot/E3LLY3 ^@ Similarity|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Monomer. http://togogenome.org/gene/31234:GCK72_020688 ^@ http://purl.uniprot.org/uniprot/E3N127 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/31234:GCK72_012859 ^@ http://purl.uniprot.org/uniprot/E3NEN2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS13 family. http://togogenome.org/gene/31234:GCK72_014579 ^@ http://purl.uniprot.org/uniprot/E3M646 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Tim17/Tim22/Tim23 family.|||Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_002248 ^@ http://purl.uniprot.org/uniprot/E3MGG3 ^@ Function|||Similarity ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. http://togogenome.org/gene/31234:GCK72_005882 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_004678 ^@ http://purl.uniprot.org/uniprot/E3MHZ6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/31234:GCK72_000543 ^@ http://purl.uniprot.org/uniprot/E3M3R8 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/31234:GCK72_024627 ^@ http://purl.uniprot.org/uniprot/E3LDD9 ^@ Similarity ^@ In the C-terminal section; belongs to the GART family.|||In the N-terminal section; belongs to the GARS family.|||In the central section; belongs to the AIR synthase family. http://togogenome.org/gene/31234:GCK72_010196 ^@ http://purl.uniprot.org/uniprot/E3MI40 ^@ Function|||Similarity ^@ Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis. http://togogenome.org/gene/31234:GCK72_001247 ^@ http://purl.uniprot.org/uniprot/E3LXJ6 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_001964 ^@ http://purl.uniprot.org/uniprot/E3LMJ0 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/31234:GCK72_018110 ^@ http://purl.uniprot.org/uniprot/E3LPR8 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/31234:GCK72_010107 ^@ http://purl.uniprot.org/uniprot/E3MD06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF5 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_003727 ^@ http://purl.uniprot.org/uniprot/E3N2S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/31234:GCK72_014019 ^@ http://purl.uniprot.org/uniprot/E3M7K3 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/31234:GCK72_008339 ^@ http://purl.uniprot.org/uniprot/E3MFT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus http://togogenome.org/gene/31234:GCK72_002080 ^@ http://purl.uniprot.org/uniprot/E3LM61 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. http://togogenome.org/gene/31234:GCK72_006017 ^@ http://purl.uniprot.org/uniprot/E3M4L1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_001720 ^@ http://purl.uniprot.org/uniprot/E3LN40 ^@ Similarity ^@ Belongs to the rtf2 family. http://togogenome.org/gene/31234:GCK72_018424 ^@ http://purl.uniprot.org/uniprot/E3LNV7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/31234:GCK72_017808 ^@ http://purl.uniprot.org/uniprot/E3LUF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_013348 ^@ http://purl.uniprot.org/uniprot/E3MRB8 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/31234:GCK72_025297 ^@ http://purl.uniprot.org/uniprot/E3MUC5 ^@ Similarity ^@ Belongs to the 'GDXG' lipolytic enzyme family. http://togogenome.org/gene/31234:GCK72_001616 ^@ http://purl.uniprot.org/uniprot/E3LNA9 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/31234:GCK72_021517 ^@ http://purl.uniprot.org/uniprot/E3MH50 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/31234:GCK72_018112 ^@ http://purl.uniprot.org/uniprot/E3LPR9 ^@ Similarity ^@ Belongs to the synaptotagmin family. http://togogenome.org/gene/31234:GCK72_006588 ^@ http://purl.uniprot.org/uniprot/E3LRN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MLF family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_000931 ^@ http://purl.uniprot.org/uniprot/E3MYG9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/31234:GCK72_021591 ^@ http://purl.uniprot.org/uniprot/E3N0K7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_016387 ^@ http://purl.uniprot.org/uniprot/E3MQQ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_014177 ^@ http://purl.uniprot.org/uniprot/E3M822 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_001154 ^@ http://purl.uniprot.org/uniprot/E3LXV1 ^@ Cofactor ^@ Binds 2 Cu(2+) ions per subunit. http://togogenome.org/gene/31234:GCK72_010724 ^@ http://purl.uniprot.org/uniprot/E3LWX2 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/31234:GCK72_002092 ^@ http://purl.uniprot.org/uniprot/E3LM46 ^@ Similarity ^@ Belongs to the vinculin/alpha-catenin family. http://togogenome.org/gene/31234:GCK72_018407 ^@ http://purl.uniprot.org/uniprot/E3LNT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_003241 ^@ http://purl.uniprot.org/uniprot/E3NJS4 ^@ Function|||Similarity ^@ Belongs to the phospholipid scramblase family.|||May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. http://togogenome.org/gene/31234:GCK72_014963 ^@ http://purl.uniprot.org/uniprot/E3M5G0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NifU family.|||Mitochondrion|||Molecular scaffold for [Fe-S] cluster assembly of mitochondrial iron-sulfur proteins. http://togogenome.org/gene/31234:GCK72_017997 ^@ http://purl.uniprot.org/uniprot/E3LTI2 ^@ Function|||Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.|||May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. http://togogenome.org/gene/31234:GCK72_019818 ^@ http://purl.uniprot.org/uniprot/E3LJ75 ^@ Function|||Similarity ^@ Belongs to the CTP synthase family.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. http://togogenome.org/gene/31234:GCK72_023090 ^@ http://purl.uniprot.org/uniprot/E3MKL3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_018304 ^@ http://purl.uniprot.org/uniprot/E3LNI1 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_025707 ^@ http://purl.uniprot.org/uniprot/E3MBY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTX family.|||Nucleus http://togogenome.org/gene/31234:GCK72_014831 ^@ http://purl.uniprot.org/uniprot/E3M510 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MVB12 family.|||Endosome membrane|||Late endosome membrane|||Membrane http://togogenome.org/gene/31234:GCK72_019688 ^@ http://purl.uniprot.org/uniprot/E3N7D2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_017022 ^@ http://purl.uniprot.org/uniprot/E3MD80 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_010151 ^@ http://purl.uniprot.org/uniprot/E3MI14 ^@ Similarity ^@ Belongs to the proteasome subunit S3 family. http://togogenome.org/gene/31234:GCK72_016360 ^@ http://purl.uniprot.org/uniprot/E3N5Y0 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/31234:GCK72_021692 ^@ http://purl.uniprot.org/uniprot/E3N843 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_008714 ^@ http://purl.uniprot.org/uniprot/E3M891 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Cell membrane|||Cytoplasmic vesicle membrane|||Golgi apparatus membrane|||Membrane|||Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity. http://togogenome.org/gene/31234:GCK72_006531 ^@ http://purl.uniprot.org/uniprot/E3LQ92 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_013573 ^@ http://purl.uniprot.org/uniprot/E3MQZ4 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_025479 ^@ http://purl.uniprot.org/uniprot/E3MJF4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_018546 ^@ http://purl.uniprot.org/uniprot/E3LP75 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_014224 ^@ http://purl.uniprot.org/uniprot/E3MSV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_021781 ^@ http://purl.uniprot.org/uniprot/E3N6F6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_013853 ^@ http://purl.uniprot.org/uniprot/E3M738 ^@ Similarity ^@ Belongs to the BLOC1S5 family. http://togogenome.org/gene/31234:GCK72_009628 ^@ http://purl.uniprot.org/uniprot/E3LRV5 ^@ Similarity ^@ Belongs to the TBCC family. http://togogenome.org/gene/31234:GCK72_014049 ^@ http://purl.uniprot.org/uniprot/E3M7N5 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/31234:GCK72_005778 ^@ http://purl.uniprot.org/uniprot/E3MMU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_023817 ^@ http://purl.uniprot.org/uniprot/E3M271 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/31234:GCK72_003663 ^@ http://purl.uniprot.org/uniprot/E3NB16 ^@ Similarity ^@ Belongs to the CWC16 family. http://togogenome.org/gene/31234:GCK72_002983 ^@ http://purl.uniprot.org/uniprot/E3N7J3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_022276 ^@ http://purl.uniprot.org/uniprot/E3M9Z4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMP family.|||Endosome membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_023753 ^@ http://purl.uniprot.org/uniprot/E3M2V7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_025192 ^@ http://purl.uniprot.org/uniprot/E3MZ92 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_005653 ^@ http://purl.uniprot.org/uniprot/E3LG57 ^@ Similarity ^@ Belongs to the UPP synthase family. http://togogenome.org/gene/31234:GCK72_003543 ^@ http://purl.uniprot.org/uniprot/E3M8V1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the flavin monoamine oxidase family.|||Histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3.|||Nucleus http://togogenome.org/gene/31234:GCK72_009492 ^@ http://purl.uniprot.org/uniprot/E3LS97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BUD31 (G10) family.|||Nucleus http://togogenome.org/gene/31234:GCK72_019962 ^@ http://purl.uniprot.org/uniprot/E3LH91 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_009981 ^@ http://purl.uniprot.org/uniprot/E3MCL8 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/31234:GCK72_010409 ^@ http://purl.uniprot.org/uniprot/E3LZH3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Ran family.|||GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.|||Nucleus http://togogenome.org/gene/31234:GCK72_019932 ^@ http://purl.uniprot.org/uniprot/E3LJJ4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_023327 ^@ http://purl.uniprot.org/uniprot/E3MAZ5 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/31234:GCK72_001031 ^@ http://purl.uniprot.org/uniprot/E3LY67 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/31234:GCK72_010480 ^@ http://purl.uniprot.org/uniprot/E3LZA8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005293 ^@ http://purl.uniprot.org/uniprot/E3LF40 ^@ Similarity ^@ Belongs to the proteasome subunit S14 family. http://togogenome.org/gene/31234:GCK72_002549 ^@ http://purl.uniprot.org/uniprot/E3LVJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRIPT family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_024266 ^@ http://purl.uniprot.org/uniprot/E3LEG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ATPase B chain family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_005577 ^@ http://purl.uniprot.org/uniprot/E3LFX5 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_000133 ^@ http://purl.uniprot.org/uniprot/E3N453 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_023502 ^@ http://purl.uniprot.org/uniprot/E3MMQ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_017911 ^@ http://purl.uniprot.org/uniprot/E3LUR6 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/31234:GCK72_008427 ^@ http://purl.uniprot.org/uniprot/E3NAD1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_000300 ^@ http://purl.uniprot.org/uniprot/E3MX57 ^@ Function|||Similarity ^@ Belongs to the ARPC5 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. http://togogenome.org/gene/31234:GCK72_005035 ^@ http://purl.uniprot.org/uniprot/E3LGN6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL10 family. http://togogenome.org/gene/31234:GCK72_016462 ^@ http://purl.uniprot.org/uniprot/E3MQX3 ^@ Function|||Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.|||Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. http://togogenome.org/gene/31234:GCK72_022800 ^@ http://purl.uniprot.org/uniprot/E3NCX4 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_019515 ^@ http://purl.uniprot.org/uniprot/E3LL53 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_019077 ^@ http://purl.uniprot.org/uniprot/E3LKH0 ^@ Similarity ^@ Belongs to the RRP15 family. http://togogenome.org/gene/31234:GCK72_016046 ^@ http://purl.uniprot.org/uniprot/E3NDC5 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/31234:GCK72_010684 ^@ http://purl.uniprot.org/uniprot/E3NH03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_025994 ^@ http://purl.uniprot.org/uniprot/E3NEZ0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_008863 ^@ http://purl.uniprot.org/uniprot/E3M8D4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family. RecQ subfamily.|||Nucleus http://togogenome.org/gene/31234:GCK72_022039 ^@ http://purl.uniprot.org/uniprot/E3NB64 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_018177 ^@ http://purl.uniprot.org/uniprot/E3LPY3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aromatic-ring hydroxylase family. KMO subfamily.|||Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.|||Membrane|||Mitochondrion http://togogenome.org/gene/31234:GCK72_009039 ^@ http://purl.uniprot.org/uniprot/E3N6Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBP family.|||Nucleus http://togogenome.org/gene/31234:GCK72_006089 ^@ http://purl.uniprot.org/uniprot/E3M4T0 ^@ Subcellular Location Annotation ^@ Golgi stack membrane http://togogenome.org/gene/31234:GCK72_010666 ^@ http://purl.uniprot.org/uniprot/E3LYQ9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_020103 ^@ http://purl.uniprot.org/uniprot/E3LHP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG9 family.|||Membrane|||Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.|||Preautophagosomal structure membrane http://togogenome.org/gene/31234:GCK72_010051 ^@ http://purl.uniprot.org/uniprot/E3MCU5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. http://togogenome.org/gene/31234:GCK72_006936 ^@ http://purl.uniprot.org/uniprot/E3M1M5 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/31234:GCK72_025473 ^@ http://purl.uniprot.org/uniprot/E3MJG1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_017789 ^@ http://purl.uniprot.org/uniprot/E3LUD9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/31234:GCK72_015994 ^@ http://purl.uniprot.org/uniprot/E3N975 ^@ Similarity ^@ Belongs to the argonaute family. http://togogenome.org/gene/31234:GCK72_010378 ^@ http://purl.uniprot.org/uniprot/E3LYF9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.|||Cytoplasm|||S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha. http://togogenome.org/gene/31234:GCK72_017341 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_006306 ^@ http://purl.uniprot.org/uniprot/E3LQZ3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_001466 ^@ http://purl.uniprot.org/uniprot/E3MFB9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005213 ^@ http://purl.uniprot.org/uniprot/E3LH62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_019333 ^@ http://purl.uniprot.org/uniprot/E3LK18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DXO/Dom3Z family.|||Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.|||Nucleus http://togogenome.org/gene/31234:GCK72_010420 ^@ http://purl.uniprot.org/uniprot/E3LZG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMO family.|||Endoplasmic reticulum membrane|||Membrane|||Microsome membrane http://togogenome.org/gene/31234:GCK72_016418 ^@ http://purl.uniprot.org/uniprot/E3MQT2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_026004 ^@ http://purl.uniprot.org/uniprot/E3NEY0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_015709 ^@ http://purl.uniprot.org/uniprot/E3MXW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/31234:GCK72_006288 ^@ http://purl.uniprot.org/uniprot/E3LR09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005640 ^@ http://purl.uniprot.org/uniprot/E3LG41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom40 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/31234:GCK72_014429 ^@ http://purl.uniprot.org/uniprot/E3MLW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||extracellular matrix http://togogenome.org/gene/31234:GCK72_013885 ^@ http://purl.uniprot.org/uniprot/E3M768 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_002064 ^@ http://purl.uniprot.org/uniprot/E3LM78 ^@ Similarity ^@ Belongs to the VPS25 family. http://togogenome.org/gene/31234:GCK72_024373 ^@ http://purl.uniprot.org/uniprot/E3LE60 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/31234:GCK72_025303 ^@ http://purl.uniprot.org/uniprot/E3MUB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.|||Membrane http://togogenome.org/gene/31234:GCK72_013744 ^@ http://purl.uniprot.org/uniprot/E3N3Y9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. http://togogenome.org/gene/31234:GCK72_013069 ^@ http://purl.uniprot.org/uniprot/E3NKN9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_021855 ^@ http://purl.uniprot.org/uniprot/E3MF85 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/31234:GCK72_010498 ^@ http://purl.uniprot.org/uniprot/E3LZ92 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SCOC family.|||Positive regulator of amino acid starvation-induced autophagy.|||trans-Golgi network http://togogenome.org/gene/31234:GCK72_004893 ^@ http://purl.uniprot.org/uniprot/E3LGA2 ^@ Similarity ^@ Belongs to the eIF-2B gamma/epsilon subunits family. http://togogenome.org/gene/31234:GCK72_006544 ^@ http://purl.uniprot.org/uniprot/E3LQ81 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_021999 ^@ http://purl.uniprot.org/uniprot/E3MEU8 ^@ Similarity ^@ Belongs to the 'GDXG' lipolytic enzyme family. http://togogenome.org/gene/31234:GCK72_011081 ^@ http://purl.uniprot.org/uniprot/E3N306 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/31234:GCK72_022279 ^@ http://purl.uniprot.org/uniprot/E3M9Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin beta chain family.|||Membrane http://togogenome.org/gene/31234:GCK72_025302 ^@ http://purl.uniprot.org/uniprot/E3MUB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thymosin beta family.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_024842 ^@ http://purl.uniprot.org/uniprot/E3LCJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_008431 ^@ http://purl.uniprot.org/uniprot/E3NAD3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UQCRH/QCR6 family.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_006116 ^@ http://purl.uniprot.org/uniprot/E3M4V6 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/31234:GCK72_017566 ^@ http://purl.uniprot.org/uniprot/E3LTQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP-25 family.|||synaptosome http://togogenome.org/gene/31234:GCK72_018746 ^@ http://purl.uniprot.org/uniprot/E3M0Q6 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_009936 ^@ http://purl.uniprot.org/uniprot/E3N9A5 ^@ Similarity ^@ Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. http://togogenome.org/gene/31234:GCK72_002556 ^@ http://purl.uniprot.org/uniprot/E3LVJ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase g subunit family.|||Membrane|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. http://togogenome.org/gene/31234:GCK72_020007 ^@ http://purl.uniprot.org/uniprot/E3LHD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_010725 ^@ http://purl.uniprot.org/uniprot/E3LWX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the REI1 family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_018921 ^@ http://purl.uniprot.org/uniprot/E3M073 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srg family. http://togogenome.org/gene/31234:GCK72_009782 ^@ http://purl.uniprot.org/uniprot/E3LT18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_002703 ^@ http://purl.uniprot.org/uniprot/E3LV20 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/31234:GCK72_003376 ^@ http://purl.uniprot.org/uniprot/E3NAA8 ^@ Similarity ^@ Belongs to the profilin family. http://togogenome.org/gene/31234:GCK72_020006 ^@ http://purl.uniprot.org/uniprot/E3LHD8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_010958 ^@ http://purl.uniprot.org/uniprot/E3LW70 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_014409 ^@ http://purl.uniprot.org/uniprot/E3MLZ1 ^@ Similarity ^@ Belongs to the RRP1 family. http://togogenome.org/gene/31234:GCK72_002002 ^@ http://purl.uniprot.org/uniprot/E3LME5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cytoplasmic vesicle membrane|||Membrane|||Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. http://togogenome.org/gene/31234:GCK72_001731 ^@ http://purl.uniprot.org/uniprot/E3LN27 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/31234:GCK72_018924 ^@ http://purl.uniprot.org/uniprot/E3M070 ^@ Similarity ^@ Belongs to the BROX family. http://togogenome.org/gene/31234:GCK72_009625 ^@ http://purl.uniprot.org/uniprot/E3LRV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PTPA-type PPIase family.|||Cytoplasm|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/31234:GCK72_021475 ^@ http://purl.uniprot.org/uniprot/E3MGZ7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_010598 ^@ http://purl.uniprot.org/uniprot/E3LYY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABI family.|||cytoskeleton|||filopodium|||lamellipodium http://togogenome.org/gene/31234:GCK72_024430 ^@ http://purl.uniprot.org/uniprot/E3LDZ8 ^@ Similarity ^@ Belongs to the MAGUK family. http://togogenome.org/gene/31234:GCK72_009702 ^@ http://purl.uniprot.org/uniprot/E3LT99 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Cytoplasm|||Maintains high levels of reduced glutathione in the cytosol. http://togogenome.org/gene/31234:GCK72_009601 ^@ http://purl.uniprot.org/uniprot/E3LRY3 ^@ Similarity ^@ Belongs to the tubulin--tyrosine ligase family. http://togogenome.org/gene/31234:GCK72_004437 ^@ http://purl.uniprot.org/uniprot/E3N190 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PCNA family.|||Nucleus|||This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. http://togogenome.org/gene/31234:GCK72_000878 ^@ http://purl.uniprot.org/uniprot/E3N4S6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL1 family. http://togogenome.org/gene/31234:GCK72_025375 ^@ http://purl.uniprot.org/uniprot/E3MJQ8 ^@ Domain|||Function|||PTM|||Subcellular Location Annotation ^@ E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.|||The WWE domain mediates non-covalent poly(ADP-ribose)-binding.|||Ubiquitinated; autoubiquitinated.|||cytosol http://togogenome.org/gene/31234:GCK72_024953 ^@ http://purl.uniprot.org/uniprot/E3MVN1 ^@ Similarity ^@ Belongs to the IL-17 family. http://togogenome.org/gene/31234:GCK72_006266 ^@ http://purl.uniprot.org/uniprot/E3LR34 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/31234:GCK72_024827 ^@ http://purl.uniprot.org/uniprot/E3LCL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_020129 ^@ http://purl.uniprot.org/uniprot/E3LHR4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_020354 ^@ http://purl.uniprot.org/uniprot/E3LII5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010661 ^@ http://purl.uniprot.org/uniprot/E3LYR4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the tryptophan 2,3-dioxygenase family.|||Binds 1 heme group per subunit.|||Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.|||Homotetramer. Dimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_001980 ^@ http://purl.uniprot.org/uniprot/E3LMH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the milton family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_022212 ^@ http://purl.uniprot.org/uniprot/E3MA61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_002138 ^@ http://purl.uniprot.org/uniprot/E3LM01 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/31234:GCK72_017722 ^@ http://purl.uniprot.org/uniprot/E3LU68 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017869 ^@ http://purl.uniprot.org/uniprot/E3LUL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. NAA40 subfamily.|||Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_005489 ^@ http://purl.uniprot.org/uniprot/E3LFN0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_000790 ^@ http://purl.uniprot.org/uniprot/E3M3H8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_025350 ^@ http://purl.uniprot.org/uniprot/E3MJT1 ^@ Similarity|||Subunit ^@ Belongs to the ENDOU family.|||Monomer. http://togogenome.org/gene/31234:GCK72_003067 ^@ http://purl.uniprot.org/uniprot/E3N008 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CSM3 family.|||Nucleus|||Plays an important role in the control of DNA replication and the maintenance of replication fork stability. http://togogenome.org/gene/31234:GCK72_005804 ^@ http://purl.uniprot.org/uniprot/E3MMR5 ^@ Similarity ^@ Belongs to the TTC38 family. http://togogenome.org/gene/31234:GCK72_018814 ^@ http://purl.uniprot.org/uniprot/E3LZP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/31234:GCK72_019786 ^@ http://purl.uniprot.org/uniprot/E3LIZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_025252 ^@ http://purl.uniprot.org/uniprot/E3MUH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone deacetylase family. HD Type 1 subfamily.|||Nucleus http://togogenome.org/gene/31234:GCK72_020183 ^@ http://purl.uniprot.org/uniprot/E3LHX2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_025690 ^@ http://purl.uniprot.org/uniprot/E3MBZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Chromosome|||Nucleus http://togogenome.org/gene/31234:GCK72_026138 ^@ http://purl.uniprot.org/uniprot/E3MPJ9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_018516 ^@ http://purl.uniprot.org/uniprot/E3LP50 ^@ Similarity ^@ Belongs to the acetyltransferase family. MAK3 subfamily. http://togogenome.org/gene/31234:GCK72_025378 ^@ http://purl.uniprot.org/uniprot/E3MJQ5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_021560 ^@ http://purl.uniprot.org/uniprot/E3NNY9 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/31234:GCK72_024615 ^@ http://purl.uniprot.org/uniprot/E3LDF3 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_016366 ^@ http://purl.uniprot.org/uniprot/E3N5Y5 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/31234:GCK72_004012 ^@ http://purl.uniprot.org/uniprot/E3MQM1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_016400 ^@ http://purl.uniprot.org/uniprot/E3MQR6 ^@ Similarity ^@ Belongs to the APC10 family. http://togogenome.org/gene/31234:GCK72_017994 ^@ http://purl.uniprot.org/uniprot/E3LTI0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_015255 ^@ http://purl.uniprot.org/uniprot/E3NDJ0 ^@ Function|||Similarity ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. http://togogenome.org/gene/31234:GCK72_012098 ^@ http://purl.uniprot.org/uniprot/E3NBC3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_024506 ^@ http://purl.uniprot.org/uniprot/E3LDR4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_015020 ^@ http://purl.uniprot.org/uniprot/E3NQM1 ^@ Similarity ^@ Belongs to the dus family. Dus3 subfamily. http://togogenome.org/gene/31234:GCK72_018508 ^@ http://purl.uniprot.org/uniprot/E3LP41 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/31234:GCK72_001606 ^@ http://purl.uniprot.org/uniprot/E3LNB8 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_009093 ^@ http://purl.uniprot.org/uniprot/E3NI41 ^@ Similarity ^@ Belongs to the TIP41 family. http://togogenome.org/gene/31234:GCK72_025589 ^@ http://purl.uniprot.org/uniprot/E3MCA4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_001829 ^@ http://purl.uniprot.org/uniprot/E3LMY1 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/31234:GCK72_018789 ^@ http://purl.uniprot.org/uniprot/E3LZM3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/31234:GCK72_009744 ^@ http://purl.uniprot.org/uniprot/E3LT50 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. http://togogenome.org/gene/31234:GCK72_018033 ^@ http://purl.uniprot.org/uniprot/E3LPJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_009405 ^@ http://purl.uniprot.org/uniprot/E3LSI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_006773 ^@ http://purl.uniprot.org/uniprot/E3M0U4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_009415 ^@ http://purl.uniprot.org/uniprot/E3LSH5 ^@ Similarity ^@ Belongs to the DNase II family. http://togogenome.org/gene/31234:GCK72_014984 ^@ http://purl.uniprot.org/uniprot/E3NP64 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_004867 ^@ http://purl.uniprot.org/uniprot/E3NEQ3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_000466 ^@ http://purl.uniprot.org/uniprot/E3MX14 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/31234:GCK72_000132 ^@ http://purl.uniprot.org/uniprot/E3N450 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. http://togogenome.org/gene/31234:GCK72_014536 ^@ http://purl.uniprot.org/uniprot/E3M690 ^@ Similarity ^@ Belongs to the MGMT family. http://togogenome.org/gene/31234:GCK72_001276 ^@ http://purl.uniprot.org/uniprot/E3LXG4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family. http://togogenome.org/gene/31234:GCK72_004043 ^@ http://purl.uniprot.org/uniprot/E3MZK3 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/31234:GCK72_005295 ^@ http://purl.uniprot.org/uniprot/E3LF42 ^@ Similarity ^@ Belongs to the hcp beta-lactamase family. http://togogenome.org/gene/31234:GCK72_014014 ^@ http://purl.uniprot.org/uniprot/E3M7J6 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/31234:GCK72_010565 ^@ http://purl.uniprot.org/uniprot/E3LZ14 ^@ Function ^@ Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA. http://togogenome.org/gene/31234:GCK72_016953 ^@ http://purl.uniprot.org/uniprot/E3MHB7 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_019508 ^@ http://purl.uniprot.org/uniprot/E3LL46 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/31234:GCK72_002681 ^@ http://purl.uniprot.org/uniprot/E3LV51 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_000994 ^@ http://purl.uniprot.org/uniprot/E3LYA2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL23 family. http://togogenome.org/gene/31234:GCK72_005933 ^@ http://purl.uniprot.org/uniprot/E3M4C4 ^@ Similarity ^@ Belongs to the UPF0415 family. http://togogenome.org/gene/31234:GCK72_001506 ^@ http://purl.uniprot.org/uniprot/E3N1N2 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/31234:GCK72_015961 ^@ http://purl.uniprot.org/uniprot/E3MYL8 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_013641 ^@ http://purl.uniprot.org/uniprot/E3MSD7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_010957 ^@ http://purl.uniprot.org/uniprot/E3LW71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS2 family.|||Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_025995 ^@ http://purl.uniprot.org/uniprot/E3NEY9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_001445 ^@ http://purl.uniprot.org/uniprot/E3MFD8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 7 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_010840 ^@ http://purl.uniprot.org/uniprot/E3LWJ9 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).|||Endosome membrane|||Late endosome membrane|||Lysosome membrane|||Membrane http://togogenome.org/gene/31234:GCK72_003597 ^@ http://purl.uniprot.org/uniprot/E3M901 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase IV family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_024660 ^@ http://purl.uniprot.org/uniprot/E3LDA2 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/31234:GCK72_004818 ^@ http://purl.uniprot.org/uniprot/E3MZT6 ^@ Function|||Similarity ^@ Belongs to the ATPase F chain family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. http://togogenome.org/gene/31234:GCK72_002327 ^@ http://purl.uniprot.org/uniprot/E3MG72 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sterol desaturase family. SCS7 subfamily.|||Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.|||Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_016965 ^@ http://purl.uniprot.org/uniprot/E3MHC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_025715 ^@ http://purl.uniprot.org/uniprot/E3MDX8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 37 family. http://togogenome.org/gene/31234:GCK72_019622 ^@ http://purl.uniprot.org/uniprot/E3LJQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_021901 ^@ http://purl.uniprot.org/uniprot/E3MF45 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017342 ^@ http://purl.uniprot.org/uniprot/E3NML2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_002290 ^@ http://purl.uniprot.org/uniprot/E3MGK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFS4 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_014902 ^@ http://purl.uniprot.org/uniprot/E3M590 ^@ Similarity ^@ Belongs to the arthropod CHH/MIH/GIH/VIH hormone family. http://togogenome.org/gene/31234:GCK72_005628 ^@ http://purl.uniprot.org/uniprot/E3LG28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_020185 ^@ http://purl.uniprot.org/uniprot/E3LHX4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_001178 ^@ http://purl.uniprot.org/uniprot/E3LXS4 ^@ Similarity ^@ Belongs to the BLCAP family. http://togogenome.org/gene/31234:GCK72_005911 ^@ http://purl.uniprot.org/uniprot/E3M4A4 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/31234:GCK72_002719 ^@ http://purl.uniprot.org/uniprot/E3LV01 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.|||Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.|||Nucleus http://togogenome.org/gene/31234:GCK72_006455 ^@ http://purl.uniprot.org/uniprot/E3LQH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protease inhibitor I33 family.|||Secreted http://togogenome.org/gene/31234:GCK72_001488 ^@ http://purl.uniprot.org/uniprot/E3N1P8 ^@ Function|||Similarity ^@ Belongs to the glycosyl hydrolase 2 family.|||Plays an important role in the degradation of dermatan and keratan sulfates. http://togogenome.org/gene/31234:GCK72_024172 ^@ http://purl.uniprot.org/uniprot/E3LEQ7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_006669 ^@ http://purl.uniprot.org/uniprot/E3M1A3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SDHAF2 family.|||Interacts with the flavoprotein subunit within the SDH catalytic dimer.|||Mitochondrion matrix|||Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. http://togogenome.org/gene/31234:GCK72_002099 ^@ http://purl.uniprot.org/uniprot/E3LM37 ^@ Similarity ^@ Belongs to the Cdt1 family. http://togogenome.org/gene/31234:GCK72_010854 ^@ http://purl.uniprot.org/uniprot/E3LWI3 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_014140 ^@ http://purl.uniprot.org/uniprot/E3M7Y5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/31234:GCK72_000776 ^@ http://purl.uniprot.org/uniprot/E3M3G5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. http://togogenome.org/gene/31234:GCK72_003584 ^@ http://purl.uniprot.org/uniprot/E3M8Y8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS2/PSF2 family.|||Component of the GINS complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_000935 ^@ http://purl.uniprot.org/uniprot/E3MYH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RPF2 family.|||nucleolus http://togogenome.org/gene/31234:GCK72_015779 ^@ http://purl.uniprot.org/uniprot/E3NGT3 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/31234:GCK72_005567 ^@ http://purl.uniprot.org/uniprot/E3LFW3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family.|||Homotetramer.|||Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA. http://togogenome.org/gene/31234:GCK72_014929 ^@ http://purl.uniprot.org/uniprot/E3M5B8 ^@ Caution|||Similarity ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_013921 ^@ http://purl.uniprot.org/uniprot/E3M7A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_019225 ^@ http://purl.uniprot.org/uniprot/E3LLD5 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. http://togogenome.org/gene/31234:GCK72_022136 ^@ http://purl.uniprot.org/uniprot/E3MAE2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_006632 ^@ http://purl.uniprot.org/uniprot/E3LRI9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_014447 ^@ http://purl.uniprot.org/uniprot/E3M6I6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_025638 ^@ http://purl.uniprot.org/uniprot/E3MC55 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. http://togogenome.org/gene/31234:GCK72_002331 ^@ http://purl.uniprot.org/uniprot/E3MG76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.|||In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.|||Nucleus http://togogenome.org/gene/31234:GCK72_016772 ^@ http://purl.uniprot.org/uniprot/E3NLA9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_014142 ^@ http://purl.uniprot.org/uniprot/E3M7Y7 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/31234:GCK72_018113 ^@ http://purl.uniprot.org/uniprot/E3LPS0 ^@ Function ^@ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. http://togogenome.org/gene/31234:GCK72_017774 ^@ http://purl.uniprot.org/uniprot/E3LUC5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|||Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).|||Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.|||Membrane http://togogenome.org/gene/31234:GCK72_016569 ^@ http://purl.uniprot.org/uniprot/E3MTV4 ^@ Subcellular Location Annotation ^@ cytosol http://togogenome.org/gene/31234:GCK72_005426 ^@ http://purl.uniprot.org/uniprot/E3LFG6 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_010338 ^@ http://purl.uniprot.org/uniprot/E3LYK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_025553 ^@ http://purl.uniprot.org/uniprot/E3MCD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_016630 ^@ http://purl.uniprot.org/uniprot/E3NGS7 ^@ Function|||Similarity ^@ Belongs to the ATPase d subunit family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. http://togogenome.org/gene/31234:GCK72_010514 ^@ http://purl.uniprot.org/uniprot/E3LZ73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the organo anion transporter (TC 2.A.60) family.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_006323 ^@ http://purl.uniprot.org/uniprot/Q6E3F2 ^@ Function ^@ Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. http://togogenome.org/gene/31234:GCK72_025782 ^@ http://purl.uniprot.org/uniprot/E3ME50 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_010604 ^@ http://purl.uniprot.org/uniprot/E3LYX5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/31234:GCK72_010481 ^@ http://purl.uniprot.org/uniprot/E3LZA7 ^@ Similarity ^@ Belongs to the RUTBC family. http://togogenome.org/gene/31234:GCK72_013341 ^@ http://purl.uniprot.org/uniprot/E3MRC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the pICln (TC 1.A.47) family.|||Nucleus http://togogenome.org/gene/31234:GCK72_002894 ^@ http://purl.uniprot.org/uniprot/E3MXM4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DAD/OST2 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/31234:GCK72_001306 ^@ http://purl.uniprot.org/uniprot/E3LXD1 ^@ Similarity ^@ Belongs to the cuticular collagen family. http://togogenome.org/gene/31234:GCK72_002432 ^@ http://purl.uniprot.org/uniprot/E3LVW8 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/31234:GCK72_018245 ^@ http://purl.uniprot.org/uniprot/E3LQ46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_014715 ^@ http://purl.uniprot.org/uniprot/E3M6S6 ^@ Similarity|||Subunit ^@ Belongs to the prefoldin subunit alpha family.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/31234:GCK72_023693 ^@ http://purl.uniprot.org/uniprot/E3M2K5 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_014352 ^@ http://purl.uniprot.org/uniprot/E3MM55 ^@ Caution|||Cofactor|||Function ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Metalloprotease. http://togogenome.org/gene/31234:GCK72_017932 ^@ http://purl.uniprot.org/uniprot/E3LUT7 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/31234:GCK72_014297 ^@ http://purl.uniprot.org/uniprot/E3MT28 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS12 family. http://togogenome.org/gene/31234:GCK72_017658 ^@ http://purl.uniprot.org/uniprot/E3LTZ8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/31234:GCK72_006291 ^@ http://purl.uniprot.org/uniprot/E3LR07 ^@ Similarity ^@ Belongs to the TRAPPC13 family. http://togogenome.org/gene/31234:GCK72_000753 ^@ http://purl.uniprot.org/uniprot/E3M3D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_013577 ^@ http://purl.uniprot.org/uniprot/E3MQZ0 ^@ Similarity ^@ Belongs to the peptidase M67A family. CSN5 subfamily. http://togogenome.org/gene/31234:GCK72_024911 ^@ http://purl.uniprot.org/uniprot/E3MVJ1 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_001658 ^@ http://purl.uniprot.org/uniprot/E3LLS7 ^@ Similarity|||Subunit ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Homodimer. http://togogenome.org/gene/31234:GCK72_017988 ^@ http://purl.uniprot.org/uniprot/E3LTH2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_014389 ^@ http://purl.uniprot.org/uniprot/E3MM13 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_014912 ^@ http://purl.uniprot.org/uniprot/E3M5A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_009270 ^@ http://purl.uniprot.org/uniprot/E3N0A2 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/31234:GCK72_012455 ^@ http://purl.uniprot.org/uniprot/E3NM14 ^@ Function|||Similarity ^@ Belongs to the TSR2 family.|||May be involved in 20S pre-rRNA processing. http://togogenome.org/gene/31234:GCK72_019377 ^@ http://purl.uniprot.org/uniprot/E3LKC8 ^@ Similarity ^@ Belongs to the exportin family. http://togogenome.org/gene/31234:GCK72_018865 ^@ http://purl.uniprot.org/uniprot/E3LKS0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_016308 ^@ http://purl.uniprot.org/uniprot/E3MYB1 ^@ Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). http://togogenome.org/gene/31234:GCK72_004802 ^@ http://purl.uniprot.org/uniprot/E3MZV1 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_002626 ^@ http://purl.uniprot.org/uniprot/E3LVB5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Nudix hydrolase family. CPSF5 subfamily.|||Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.|||Cytoplasm|||Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_010944 ^@ http://purl.uniprot.org/uniprot/E3LW84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein srb family.|||Membrane http://togogenome.org/gene/31234:GCK72_001663 ^@ http://purl.uniprot.org/uniprot/E3LLS2 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/31234:GCK72_016123 ^@ http://purl.uniprot.org/uniprot/E3N9U3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_001104 ^@ http://purl.uniprot.org/uniprot/E3LXZ7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_015367 ^@ http://purl.uniprot.org/uniprot/E3N8C7 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/31234:GCK72_004937 ^@ http://purl.uniprot.org/uniprot/E3LGE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family. BCS1 subfamily.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_019142 ^@ http://purl.uniprot.org/uniprot/E3LKT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane http://togogenome.org/gene/31234:GCK72_002512 ^@ http://purl.uniprot.org/uniprot/Q6E3E5 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/31234:GCK72_018462 ^@ http://purl.uniprot.org/uniprot/E3LNZ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SWEET sugar transporter family.|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediates sugar transport across membranes.|||Membrane http://togogenome.org/gene/31234:GCK72_006597 ^@ http://purl.uniprot.org/uniprot/E3LRM3 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/31234:GCK72_010032 ^@ http://purl.uniprot.org/uniprot/E3MCS5 ^@ Similarity ^@ Belongs to the maelstrom family. http://togogenome.org/gene/31234:GCK72_017516 ^@ http://purl.uniprot.org/uniprot/E3LTK3 ^@ Similarity ^@ Belongs to the NXF family. http://togogenome.org/gene/31234:GCK72_024984 ^@ http://purl.uniprot.org/uniprot/E3MRN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_012453 ^@ http://purl.uniprot.org/uniprot/E3NWZ6 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_016507 ^@ http://purl.uniprot.org/uniprot/E3N791 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||Nucleus|||Required for pre-mRNA splicing. http://togogenome.org/gene/31234:GCK72_008936 ^@ http://purl.uniprot.org/uniprot/E3MWI9 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_007622 ^@ http://purl.uniprot.org/uniprot/E3M989 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_017227 ^@ http://purl.uniprot.org/uniprot/E3NKS6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_000815 ^@ http://purl.uniprot.org/uniprot/E3M3K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sestrin family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_011886 ^@ http://purl.uniprot.org/uniprot/E3ML98 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/31234:GCK72_018314 ^@ http://purl.uniprot.org/uniprot/E3LNI9 ^@ Similarity ^@ Belongs to the alpha-actinin family. http://togogenome.org/gene/31234:GCK72_017553 ^@ http://purl.uniprot.org/uniprot/E3LTN9 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_003600 ^@ http://purl.uniprot.org/uniprot/E3M904 ^@ Function|||Similarity ^@ Belongs to the VPS28 family.|||Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. http://togogenome.org/gene/31234:GCK72_016940 ^@ http://purl.uniprot.org/uniprot/E3MHM1 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/31234:GCK72_009327 ^@ http://purl.uniprot.org/uniprot/E3N051 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the malectin family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_013700 ^@ http://purl.uniprot.org/uniprot/E3MS69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_011698 ^@ http://purl.uniprot.org/uniprot/E3NAK5 ^@ Similarity ^@ Belongs to the protein disulfide isomerase family. http://togogenome.org/gene/31234:GCK72_023761 ^@ http://purl.uniprot.org/uniprot/E3M2W2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_017569 ^@ http://purl.uniprot.org/uniprot/E3LTQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ro 60 kDa family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_016307 ^@ http://purl.uniprot.org/uniprot/E3MYB2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017104 ^@ http://purl.uniprot.org/uniprot/E3ND05 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 3-HAO family.|||Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_017657 ^@ http://purl.uniprot.org/uniprot/E3LTZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP receptor beta subunit family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_004453 ^@ http://purl.uniprot.org/uniprot/E3NG49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005040 ^@ http://purl.uniprot.org/uniprot/E3LGP2 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/31234:GCK72_004680 ^@ http://purl.uniprot.org/uniprot/E3MHZ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycogen debranching enzyme family.|||Cytoplasm|||Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation. http://togogenome.org/gene/31234:GCK72_022013 ^@ http://purl.uniprot.org/uniprot/E3MET5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 17 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_000333 ^@ http://purl.uniprot.org/uniprot/E3MX92 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/31234:GCK72_003732 ^@ http://purl.uniprot.org/uniprot/E3N2R9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_004951 ^@ http://purl.uniprot.org/uniprot/E3LGG2 ^@ Similarity ^@ Belongs to the argonaute family. http://togogenome.org/gene/31234:GCK72_023189 ^@ http://purl.uniprot.org/uniprot/E3MKQ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_004800 ^@ http://purl.uniprot.org/uniprot/E3MZV2 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_009271 ^@ http://purl.uniprot.org/uniprot/E3N0A0 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_011247 ^@ http://purl.uniprot.org/uniprot/E3MW98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_025692 ^@ http://purl.uniprot.org/uniprot/E3MBZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the APC5 family.|||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.|||spindle http://togogenome.org/gene/31234:GCK72_025891 ^@ http://purl.uniprot.org/uniprot/E3MDW2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_000450 ^@ http://purl.uniprot.org/uniprot/E3MWZ8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_013675 ^@ http://purl.uniprot.org/uniprot/E3MS95 ^@ Similarity ^@ Belongs to the tRNA pseudouridine synthase TruA family. http://togogenome.org/gene/31234:GCK72_006160 ^@ http://purl.uniprot.org/uniprot/E3LRE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_017041 ^@ http://purl.uniprot.org/uniprot/E3MD98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/31234:GCK72_026121 ^@ http://purl.uniprot.org/uniprot/E3NK30 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_016668 ^@ http://purl.uniprot.org/uniprot/E3NKR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Spartan family.|||Chromosome|||Nucleus http://togogenome.org/gene/31234:GCK72_016548 ^@ http://purl.uniprot.org/uniprot/E3MTX6 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_017604 ^@ http://purl.uniprot.org/uniprot/E3LTU1 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/31234:GCK72_002900 ^@ http://purl.uniprot.org/uniprot/E3MXL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/31234:GCK72_017848 ^@ http://purl.uniprot.org/uniprot/E3LUK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 23 family.|||Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.|||Golgi stack membrane|||Membrane http://togogenome.org/gene/31234:GCK72_005469 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_014090 ^@ http://purl.uniprot.org/uniprot/E3M7T2 ^@ Function|||Similarity ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. http://togogenome.org/gene/31234:GCK72_015252 ^@ http://purl.uniprot.org/uniprot/E3NDJ2 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/31234:GCK72_018102 ^@ http://purl.uniprot.org/uniprot/E3LPR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Membrane http://togogenome.org/gene/31234:GCK72_006729 ^@ http://purl.uniprot.org/uniprot/E3M0Z7 ^@ Caution|||Similarity ^@ Belongs to the nematode receptor-like protein srg family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_010527 ^@ http://purl.uniprot.org/uniprot/E3LZ59 ^@ Similarity ^@ Belongs to the protein phosphatase inhibitor 2 family. http://togogenome.org/gene/31234:GCK72_006676 ^@ http://purl.uniprot.org/uniprot/E3M197 ^@ Similarity ^@ Belongs to the CAF1 family. http://togogenome.org/gene/31234:GCK72_001111 ^@ http://purl.uniprot.org/uniprot/E3LXZ1 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/31234:GCK72_010382 ^@ http://purl.uniprot.org/uniprot/E3LYF4 ^@ Similarity ^@ Belongs to the PDE6D/unc-119 family. http://togogenome.org/gene/31234:GCK72_011258 ^@ http://purl.uniprot.org/uniprot/E3MWA6 ^@ Similarity ^@ Belongs to the NPC2 family. http://togogenome.org/gene/31234:GCK72_017404 ^@ http://purl.uniprot.org/uniprot/E3MN54 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/31234:GCK72_000974 ^@ http://purl.uniprot.org/uniprot/E3LYC9 ^@ Similarity ^@ Belongs to the argonaute family. http://togogenome.org/gene/31234:GCK72_005893 ^@ http://purl.uniprot.org/uniprot/E3M485 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_004926 ^@ http://purl.uniprot.org/uniprot/E3LGD9 ^@ Similarity ^@ Belongs to the SEC2 family. http://togogenome.org/gene/31234:GCK72_010456 ^@ http://purl.uniprot.org/uniprot/E3LZD2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_000568 ^@ http://purl.uniprot.org/uniprot/E3M3U6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_016841 ^@ http://purl.uniprot.org/uniprot/E3MQ23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/31234:GCK72_017760 ^@ http://purl.uniprot.org/uniprot/E3LUB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the kinesin light chain family.|||Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.|||Oligomeric complex composed of two heavy chains and two light chains.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_000606 ^@ http://purl.uniprot.org/uniprot/E3M3Y9 ^@ Similarity|||Subunit ^@ Belongs to the ENDOU family.|||Monomer. http://togogenome.org/gene/31234:GCK72_004578 ^@ http://purl.uniprot.org/uniprot/E3MHW6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_005327 ^@ http://purl.uniprot.org/uniprot/E3LF74 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_007922 ^@ http://purl.uniprot.org/uniprot/E3N1Y8 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_010341 ^@ http://purl.uniprot.org/uniprot/E3LYK2 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/31234:GCK72_024544 ^@ http://purl.uniprot.org/uniprot/E3LDM4 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/31234:GCK72_018354 ^@ http://purl.uniprot.org/uniprot/E3LNM6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/31234:GCK72_015180 ^@ http://purl.uniprot.org/uniprot/E3N2G6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase epsilon subunit B family.|||Nucleus|||Participates in DNA repair and in chromosomal DNA replication. http://togogenome.org/gene/31234:GCK72_005921 ^@ http://purl.uniprot.org/uniprot/E3M4B3 ^@ Similarity ^@ Belongs to the SURF6 family. http://togogenome.org/gene/31234:GCK72_000014 ^@ http://purl.uniprot.org/uniprot/E3MT78 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. http://togogenome.org/gene/31234:GCK72_010730 ^@ http://purl.uniprot.org/uniprot/E3LWW7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/31234:GCK72_002589 ^@ http://purl.uniprot.org/uniprot/E3LVF1 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_021754 ^@ http://purl.uniprot.org/uniprot/E3N6I5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010584 ^@ http://purl.uniprot.org/uniprot/E3LYZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_006584 ^@ http://purl.uniprot.org/uniprot/E3LRN6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_013545 ^@ http://purl.uniprot.org/uniprot/E3MR28 ^@ Function|||Similarity ^@ Belongs to the MON1/SAND family.|||Plays an important role in membrane trafficking through the secretory apparatus. http://togogenome.org/gene/31234:GCK72_020590 ^@ http://purl.uniprot.org/uniprot/E3MWM2 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/31234:GCK72_019149 ^@ http://purl.uniprot.org/uniprot/E3LKT9 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/31234:GCK72_020188 ^@ http://purl.uniprot.org/uniprot/E3LHX7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_008222 ^@ http://purl.uniprot.org/uniprot/E3MP05 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/31234:GCK72_019976 ^@ http://purl.uniprot.org/uniprot/E3LHA5 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/31234:GCK72_018527 ^@ http://purl.uniprot.org/uniprot/E3LP60 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srg family. http://togogenome.org/gene/31234:GCK72_001940 ^@ http://purl.uniprot.org/uniprot/E3LML4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the battenin family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/31234:GCK72_011102 ^@ http://purl.uniprot.org/uniprot/E3N2Y8 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_009589 ^@ http://purl.uniprot.org/uniprot/E3LRZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTF2H2 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_016052 ^@ http://purl.uniprot.org/uniprot/E3NDB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tyrosyl-DNA phosphodiesterase family.|||Nucleus http://togogenome.org/gene/31234:GCK72_015871 ^@ http://purl.uniprot.org/uniprot/E3N9P5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_006620 ^@ http://purl.uniprot.org/uniprot/E3LRJ5 ^@ Similarity ^@ Belongs to the TRM112 family. http://togogenome.org/gene/31234:GCK72_001771 ^@ http://purl.uniprot.org/uniprot/E3LLR5 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/31234:GCK72_014355 ^@ http://purl.uniprot.org/uniprot/E3MM47 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_013855 ^@ http://purl.uniprot.org/uniprot/E3M745 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP23 family.|||Membrane http://togogenome.org/gene/31234:GCK72_014966 ^@ http://purl.uniprot.org/uniprot/E3NU70 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_023401 ^@ http://purl.uniprot.org/uniprot/E3MAK3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/31234:GCK72_021582 ^@ http://purl.uniprot.org/uniprot/E3NDM3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_009709 ^@ http://purl.uniprot.org/uniprot/E3LT91 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_006000 ^@ http://purl.uniprot.org/uniprot/E3M4J5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MESD family.|||Endoplasmic reticulum http://togogenome.org/gene/31234:GCK72_016865 ^@ http://purl.uniprot.org/uniprot/E3NAX9 ^@ Similarity ^@ Belongs to the RuvB family. http://togogenome.org/gene/31234:GCK72_016348 ^@ http://purl.uniprot.org/uniprot/E3N5W7 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_016384 ^@ http://purl.uniprot.org/uniprot/E3MQP8 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/31234:GCK72_009040 ^@ http://purl.uniprot.org/uniprot/E3N6Q3 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/31234:GCK72_006337 ^@ http://purl.uniprot.org/uniprot/E3LQV9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_009959 ^@ http://purl.uniprot.org/uniprot/E3MCJ6 ^@ Similarity ^@ Belongs to the CSN12 family. http://togogenome.org/gene/31234:GCK72_010787 ^@ http://purl.uniprot.org/uniprot/E3LWQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.|||Belongs to the TRM44 family.|||Cytoplasm|||Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase. http://togogenome.org/gene/31234:GCK72_013574 ^@ http://purl.uniprot.org/uniprot/E3MQZ3 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_010475 ^@ http://purl.uniprot.org/uniprot/E3LZB2 ^@ Similarity ^@ Belongs to the HAT1 family. http://togogenome.org/gene/31234:GCK72_006238 ^@ http://purl.uniprot.org/uniprot/E3LR67 ^@ Similarity ^@ Belongs to the Asterix family. http://togogenome.org/gene/31234:GCK72_010952 ^@ http://purl.uniprot.org/uniprot/E3LW76 ^@ Similarity ^@ Belongs to the RMD1/sif2 family. http://togogenome.org/gene/31234:GCK72_006501 ^@ http://purl.uniprot.org/uniprot/E3LQC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_020898 ^@ http://purl.uniprot.org/uniprot/E3MBE1 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/31234:GCK72_006733 ^@ http://purl.uniprot.org/uniprot/E3M0Z2 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srg family. http://togogenome.org/gene/31234:GCK72_017120 ^@ http://purl.uniprot.org/uniprot/E3NKM0 ^@ Similarity ^@ Belongs to the MAD1 family. http://togogenome.org/gene/31234:GCK72_014268 ^@ http://purl.uniprot.org/uniprot/E3MSZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_025403 ^@ http://purl.uniprot.org/uniprot/E3MJM9 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_006643 ^@ http://purl.uniprot.org/uniprot/E3LRH6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL43 family. http://togogenome.org/gene/31234:GCK72_001535 ^@ http://purl.uniprot.org/uniprot/E3N1K3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. http://togogenome.org/gene/31234:GCK72_001848 ^@ http://purl.uniprot.org/uniprot/E3LMW0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/31234:GCK72_017514 ^@ http://purl.uniprot.org/uniprot/E3LTK1 ^@ Similarity ^@ Belongs to the NXF family. http://togogenome.org/gene/31234:GCK72_022930 ^@ http://purl.uniprot.org/uniprot/E3MLS5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_018175 ^@ http://purl.uniprot.org/uniprot/E3LPX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_012722 ^@ http://purl.uniprot.org/uniprot/E3NNV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/31234:GCK72_001147 ^@ http://purl.uniprot.org/uniprot/E3LXV8 ^@ Similarity ^@ Belongs to the G-alpha family. G(q) subfamily. http://togogenome.org/gene/31234:GCK72_014087 ^@ http://purl.uniprot.org/uniprot/E3M7S9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_019981 ^@ http://purl.uniprot.org/uniprot/E3LHB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_015479 ^@ http://purl.uniprot.org/uniprot/E3NG83 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_000898 ^@ http://purl.uniprot.org/uniprot/E3MYE2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/31234:GCK72_011193 ^@ http://purl.uniprot.org/uniprot/E3NFT8 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_009297 ^@ http://purl.uniprot.org/uniprot/E3N081 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/31234:GCK72_012441 ^@ http://purl.uniprot.org/uniprot/E3NH34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Chromosome|||Nucleus http://togogenome.org/gene/31234:GCK72_014811 ^@ http://purl.uniprot.org/uniprot/E3M4Z4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/31234:GCK72_006471 ^@ http://purl.uniprot.org/uniprot/E3LQF8 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/31234:GCK72_025747 ^@ http://purl.uniprot.org/uniprot/E3ME14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/31234:GCK72_024729 ^@ http://purl.uniprot.org/uniprot/E3LD32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_022220 ^@ http://purl.uniprot.org/uniprot/E3MA53 ^@ Similarity ^@ Belongs to the peptidase S28 family. http://togogenome.org/gene/31234:GCK72_019873 ^@ http://purl.uniprot.org/uniprot/E3LJD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_008413 ^@ http://purl.uniprot.org/uniprot/E3NAB8 ^@ Similarity ^@ Belongs to the MIP18 family. http://togogenome.org/gene/31234:GCK72_024425 ^@ http://purl.uniprot.org/uniprot/E3LE03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ITM2 family.|||Membrane http://togogenome.org/gene/31234:GCK72_002073 ^@ http://purl.uniprot.org/uniprot/E3LM68 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_017510 ^@ http://purl.uniprot.org/uniprot/E3LTJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.|||nucleolus http://togogenome.org/gene/31234:GCK72_018224 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_002601 ^@ http://purl.uniprot.org/uniprot/E3LVE0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL24 family. http://togogenome.org/gene/31234:GCK72_016302 ^@ http://purl.uniprot.org/uniprot/E3MYB8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. http://togogenome.org/gene/31234:GCK72_016705 ^@ http://purl.uniprot.org/uniprot/E3NF94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/31234:GCK72_001313 ^@ http://purl.uniprot.org/uniprot/E3LXC3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005036 ^@ http://purl.uniprot.org/uniprot/E3LGN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_009710 ^@ http://purl.uniprot.org/uniprot/E3LT85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_006644 ^@ http://purl.uniprot.org/uniprot/E3LRH4 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/31234:GCK72_001027 ^@ http://purl.uniprot.org/uniprot/E3LY71 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_003631 ^@ http://purl.uniprot.org/uniprot/E3NAV7 ^@ Similarity ^@ Belongs to the UQCRB/QCR7 family. http://togogenome.org/gene/31234:GCK72_006398 ^@ http://purl.uniprot.org/uniprot/E3LQN5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_007516 ^@ http://purl.uniprot.org/uniprot/E3MUP6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_018233 ^@ http://purl.uniprot.org/uniprot/E3LKS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_010426 ^@ http://purl.uniprot.org/uniprot/E3LZG1 ^@ Similarity ^@ Belongs to the centaurin gamma-like family. http://togogenome.org/gene/31234:GCK72_020921 ^@ http://purl.uniprot.org/uniprot/E3MBB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_000007 ^@ http://purl.uniprot.org/uniprot/E3MT85 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_018876 ^@ http://purl.uniprot.org/uniprot/E3LZW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005593 ^@ http://purl.uniprot.org/uniprot/E3LFZ3 ^@ Similarity ^@ Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. http://togogenome.org/gene/31234:GCK72_013540 ^@ http://purl.uniprot.org/uniprot/E3MR35 ^@ Similarity ^@ Belongs to the histone deacetylase family. HD type 2 subfamily. http://togogenome.org/gene/31234:GCK72_010649 ^@ http://purl.uniprot.org/uniprot/E3LYT0 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/31234:GCK72_008931 ^@ http://purl.uniprot.org/uniprot/E3N6K5 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_003585 ^@ http://purl.uniprot.org/uniprot/E3M8Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metaxin family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/31234:GCK72_000474 ^@ http://purl.uniprot.org/uniprot/E3MX24 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/31234:GCK72_013687 ^@ http://purl.uniprot.org/uniprot/E3MS81 ^@ Caution|||Similarity ^@ Belongs to the secreted frizzled-related protein (sFRP) family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_007830 ^@ http://purl.uniprot.org/uniprot/E3NB96 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_001401 ^@ http://purl.uniprot.org/uniprot/E3MFI7 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/31234:GCK72_014072 ^@ http://purl.uniprot.org/uniprot/E3M7R2 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/31234:GCK72_006551 ^@ http://purl.uniprot.org/uniprot/E3LRS0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_025372 ^@ http://purl.uniprot.org/uniprot/E3MJQ9 ^@ Domain|||Function|||PTM|||Subcellular Location Annotation ^@ E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.|||The WWE domain mediates non-covalent poly(ADP-ribose)-binding.|||Ubiquitinated; autoubiquitinated.|||cytosol http://togogenome.org/gene/31234:GCK72_017769 ^@ http://purl.uniprot.org/uniprot/E3LUC0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_023302 ^@ http://purl.uniprot.org/uniprot/E3MAX5 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_000540 ^@ http://purl.uniprot.org/uniprot/E3M3R4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/31234:GCK72_009849 ^@ http://purl.uniprot.org/uniprot/E3LSV2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA10 subunit family.|||Mitochondrion matrix http://togogenome.org/gene/31234:GCK72_016465 ^@ http://purl.uniprot.org/uniprot/E3MQX5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_005781 ^@ http://purl.uniprot.org/uniprot/E3MMU1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/31234:GCK72_016304 ^@ http://purl.uniprot.org/uniprot/E3MYB5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/31234:GCK72_010783 ^@ http://purl.uniprot.org/uniprot/E3LWQ7 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/31234:GCK72_000685 ^@ http://purl.uniprot.org/uniprot/E3M393 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/31234:GCK72_013750 ^@ http://purl.uniprot.org/uniprot/E3N3X7 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_025718 ^@ http://purl.uniprot.org/uniprot/E3MDY1 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_006151 ^@ http://purl.uniprot.org/uniprot/E3LRF1 ^@ Similarity ^@ Belongs to the frataxin family. http://togogenome.org/gene/31234:GCK72_025757 ^@ http://purl.uniprot.org/uniprot/E3ME25 ^@ Function ^@ May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols. http://togogenome.org/gene/31234:GCK72_018324 ^@ http://purl.uniprot.org/uniprot/E3LNK1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_009921 ^@ http://purl.uniprot.org/uniprot/E3N9C0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_013799 ^@ http://purl.uniprot.org/uniprot/E3NE85 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_006772 ^@ http://purl.uniprot.org/uniprot/E3M0U5 ^@ Similarity ^@ Belongs to the NECAP family. http://togogenome.org/gene/31234:GCK72_021898 ^@ http://purl.uniprot.org/uniprot/E3MF48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_022738 ^@ http://purl.uniprot.org/uniprot/E3N6C1 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/31234:GCK72_021003 ^@ http://purl.uniprot.org/uniprot/E3MTK2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_013542 ^@ http://purl.uniprot.org/uniprot/E3MR31 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_016082 ^@ http://purl.uniprot.org/uniprot/E3NH75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC61-beta family.|||Endoplasmic reticulum membrane|||Membrane|||Necessary for protein translocation in the endoplasmic reticulum. http://togogenome.org/gene/31234:GCK72_017125 ^@ http://purl.uniprot.org/uniprot/E3NKL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_024021 ^@ http://purl.uniprot.org/uniprot/E3LCQ5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_016722 ^@ http://purl.uniprot.org/uniprot/E3MQE0 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_000136 ^@ http://purl.uniprot.org/uniprot/E3N464 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_006243 ^@ http://purl.uniprot.org/uniprot/E3LR62 ^@ Similarity ^@ Belongs to the ATPase epsilon chain family. http://togogenome.org/gene/31234:GCK72_015299 ^@ http://purl.uniprot.org/uniprot/E3NIS8 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/31234:GCK72_005872 ^@ http://purl.uniprot.org/uniprot/E3M461 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOT1 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_019483 ^@ http://purl.uniprot.org/uniprot/E3LL17 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001633 ^@ http://purl.uniprot.org/uniprot/E3LLV4 ^@ Function|||Similarity ^@ Belongs to the eukaryotic/archaeal RNase P protein component 1 family.|||Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. http://togogenome.org/gene/31234:GCK72_014107 ^@ http://purl.uniprot.org/uniprot/E3NJX4 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/31234:GCK72_002548 ^@ http://purl.uniprot.org/uniprot/E3LVJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/31234:GCK72_020052 ^@ http://purl.uniprot.org/uniprot/E3LHJ0 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/31234:GCK72_005180 ^@ http://purl.uniprot.org/uniprot/E3LH29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/31234:GCK72_010750 ^@ http://purl.uniprot.org/uniprot/E3LWU5 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_021336 ^@ http://purl.uniprot.org/uniprot/E3N8J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase U48 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_009832 ^@ http://purl.uniprot.org/uniprot/E3LSW9 ^@ Function|||Similarity ^@ Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis. http://togogenome.org/gene/31234:GCK72_012271 ^@ http://purl.uniprot.org/uniprot/E3N3R9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrimidine 5'-nucleotidase family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_003715 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_013594 ^@ http://purl.uniprot.org/uniprot/E3MJW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_014223 ^@ http://purl.uniprot.org/uniprot/E3MSV3 ^@ Similarity ^@ Belongs to the strictosidine synthase family. http://togogenome.org/gene/31234:GCK72_019608 ^@ http://purl.uniprot.org/uniprot/E3LJP4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_004986 ^@ http://purl.uniprot.org/uniprot/E3LGJ3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/31234:GCK72_011678 ^@ http://purl.uniprot.org/uniprot/E3NAJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_024825 ^@ http://purl.uniprot.org/uniprot/E3LCL2 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/31234:GCK72_006117 ^@ http://purl.uniprot.org/uniprot/E3M4V7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010205 ^@ http://purl.uniprot.org/uniprot/E3MI52 ^@ Similarity ^@ Belongs to the MIF family. http://togogenome.org/gene/31234:GCK72_006122 ^@ http://purl.uniprot.org/uniprot/E3M4W2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/31234:GCK72_005966 ^@ http://purl.uniprot.org/uniprot/E3M4G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein srb family.|||Membrane http://togogenome.org/gene/31234:GCK72_010118 ^@ http://purl.uniprot.org/uniprot/E3MD17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_017176 ^@ http://purl.uniprot.org/uniprot/E3N553 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_005475 ^@ http://purl.uniprot.org/uniprot/E3LFL0 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_001414 ^@ http://purl.uniprot.org/uniprot/E3MFH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the APH-1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_008524 ^@ http://purl.uniprot.org/uniprot/E3NHF2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat PRP19 family.|||Homotetramer.|||Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.|||nucleoplasm http://togogenome.org/gene/31234:GCK72_009822 ^@ http://purl.uniprot.org/uniprot/E3LSX7 ^@ Similarity|||Subunit ^@ Belongs to the prefoldin subunit alpha family.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/31234:GCK72_014446 ^@ http://purl.uniprot.org/uniprot/E3M6I7 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_010120 ^@ http://purl.uniprot.org/uniprot/E3MD19 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. LCMT family.|||Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. http://togogenome.org/gene/31234:GCK72_009675 ^@ http://purl.uniprot.org/uniprot/E3LTC3 ^@ Similarity ^@ Belongs to the CTAG/PCC1 family. http://togogenome.org/gene/31234:GCK72_018790 ^@ http://purl.uniprot.org/uniprot/E3LZM4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_008145 ^@ http://purl.uniprot.org/uniprot/E3MDF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_001008 ^@ http://purl.uniprot.org/uniprot/E3LY88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).|||Belongs to the VPS51 family.|||Component of the Golgi-associated retrograde protein (GARP) complex.|||trans-Golgi network http://togogenome.org/gene/31234:GCK72_006778 ^@ http://purl.uniprot.org/uniprot/E3M0T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_003699 ^@ http://purl.uniprot.org/uniprot/E3N2V6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK6 subfamily.|||Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity.|||Monomer and homodimer.|||Nucleus http://togogenome.org/gene/31234:GCK72_021976 ^@ http://purl.uniprot.org/uniprot/E3MEX2 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/31234:GCK72_024989 ^@ http://purl.uniprot.org/uniprot/E3MRN8 ^@ Similarity ^@ Belongs to the TSC-22/Dip/Bun family. http://togogenome.org/gene/31234:GCK72_013660 ^@ http://purl.uniprot.org/uniprot/E3MSB5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_012095 ^@ http://purl.uniprot.org/uniprot/E3NBB9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_000310 ^@ http://purl.uniprot.org/uniprot/E3MX69 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_014407 ^@ http://purl.uniprot.org/uniprot/E3NL46 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. http://togogenome.org/gene/31234:GCK72_015008 ^@ http://purl.uniprot.org/uniprot/E3M5L5 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/31234:GCK72_018191 ^@ http://purl.uniprot.org/uniprot/E3LPZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_019224 ^@ http://purl.uniprot.org/uniprot/E3LLD4 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. http://togogenome.org/gene/31234:GCK72_009694 ^@ http://purl.uniprot.org/uniprot/E3LTA6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/31234:GCK72_024470 ^@ http://purl.uniprot.org/uniprot/E3LDV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF4 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_005575 ^@ http://purl.uniprot.org/uniprot/E3LFX3 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/31234:GCK72_008520 ^@ http://purl.uniprot.org/uniprot/E3NHE9 ^@ Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Homodimer. http://togogenome.org/gene/31234:GCK72_000933 ^@ http://purl.uniprot.org/uniprot/E3MYH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.|||Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_019458 ^@ http://purl.uniprot.org/uniprot/E3LKW9 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Putative Notch ligand involved in the mediation of Notch signaling. http://togogenome.org/gene/31234:GCK72_013917 ^@ http://purl.uniprot.org/uniprot/E3LKS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_018026 ^@ http://purl.uniprot.org/uniprot/E3LPI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_016537 ^@ http://purl.uniprot.org/uniprot/E3MTY7 ^@ Function|||Subunit ^@ EF-1 is composed of four subunits: alpha, beta, delta, and gamma.|||Probably plays a role in anchoring the complex to other cellular components. http://togogenome.org/gene/31234:GCK72_019558 ^@ http://purl.uniprot.org/uniprot/E3LLE7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_019151 ^@ http://purl.uniprot.org/uniprot/E3LKU1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||Nucleus|||Required for pre-mRNA splicing. http://togogenome.org/gene/31234:GCK72_023766 ^@ http://purl.uniprot.org/uniprot/E3M2W6 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/31234:GCK72_023677 ^@ http://purl.uniprot.org/uniprot/E3M2F5 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. http://togogenome.org/gene/31234:GCK72_022236 ^@ http://purl.uniprot.org/uniprot/E3MA37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sphingomyelin synthase family.|||Membrane http://togogenome.org/gene/31234:GCK72_020003 ^@ http://purl.uniprot.org/uniprot/E3LHD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_001230 ^@ http://purl.uniprot.org/uniprot/E3LXM1 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/31234:GCK72_018888 ^@ http://purl.uniprot.org/uniprot/E3LK36 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/31234:GCK72_023492 ^@ http://purl.uniprot.org/uniprot/E3MMD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/31234:GCK72_015921 ^@ http://purl.uniprot.org/uniprot/E3NEV2 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/31234:GCK72_023405 ^@ http://purl.uniprot.org/uniprot/E3MAK6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_009661 ^@ http://purl.uniprot.org/uniprot/E3LRS6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA8 subunit family.|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/31234:GCK72_006508 ^@ http://purl.uniprot.org/uniprot/E3LQC1 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_001363 ^@ http://purl.uniprot.org/uniprot/E3MFM9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_015928 ^@ http://purl.uniprot.org/uniprot/E3NEV6 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/31234:GCK72_018225 ^@ http://purl.uniprot.org/uniprot/E3LQ26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_019064 ^@ http://purl.uniprot.org/uniprot/E3LKC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_024995 ^@ http://purl.uniprot.org/uniprot/E3MRP4 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/31234:GCK72_009835 ^@ http://purl.uniprot.org/uniprot/E3LSW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein srb family.|||Membrane http://togogenome.org/gene/31234:GCK72_019093 ^@ http://purl.uniprot.org/uniprot/E3LKF8 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_020073 ^@ http://purl.uniprot.org/uniprot/E3LHK7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_016963 ^@ http://purl.uniprot.org/uniprot/E3MHC5 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_006495 ^@ http://purl.uniprot.org/uniprot/E3LQD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/31234:GCK72_017790 ^@ http://purl.uniprot.org/uniprot/E3LUE0 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/31234:GCK72_025645 ^@ http://purl.uniprot.org/uniprot/E3MC49 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TIKI family.|||Cell membrane|||Divalent metal cations. Mn(2+) or Co(2+).|||Membrane|||Metalloprotease that acts as a negative regulator of the Wnt signaling pathway. http://togogenome.org/gene/31234:GCK72_001277 ^@ http://purl.uniprot.org/uniprot/E3LXG2 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_008279 ^@ http://purl.uniprot.org/uniprot/E3MG09 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/31234:GCK72_013161 ^@ http://purl.uniprot.org/uniprot/E3NNE5 ^@ Similarity ^@ Belongs to the UPF0375 family. http://togogenome.org/gene/31234:GCK72_009115 ^@ http://purl.uniprot.org/uniprot/E3MKT3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_020439 ^@ http://purl.uniprot.org/uniprot/E3LIS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_018405 ^@ http://purl.uniprot.org/uniprot/E3LNT1 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_010060 ^@ http://purl.uniprot.org/uniprot/E3MCV8 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/31234:GCK72_010850 ^@ http://purl.uniprot.org/uniprot/E3LWI8 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_018426 ^@ http://purl.uniprot.org/uniprot/E3LNV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_009060 ^@ http://purl.uniprot.org/uniprot/E3N6S3 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/31234:GCK72_017948 ^@ http://purl.uniprot.org/uniprot/E3LUV2 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/31234:GCK72_009031 ^@ http://purl.uniprot.org/uniprot/E3MWI4 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_020106 ^@ http://purl.uniprot.org/uniprot/E3LHP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/31234:GCK72_019330 ^@ http://purl.uniprot.org/uniprot/E3LK16 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/31234:GCK72_025800 ^@ http://purl.uniprot.org/uniprot/E3ME70 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_024148 ^@ http://purl.uniprot.org/uniprot/E3LET2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/31234:GCK72_001192 ^@ http://purl.uniprot.org/uniprot/E3LXR2 ^@ Similarity ^@ Belongs to the 'GDXG' lipolytic enzyme family. http://togogenome.org/gene/31234:GCK72_010628 ^@ http://purl.uniprot.org/uniprot/E3LKF8 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_002379 ^@ http://purl.uniprot.org/uniprot/E3LW22 ^@ Similarity ^@ Belongs to the SKA1 family. http://togogenome.org/gene/31234:GCK72_000117 ^@ http://purl.uniprot.org/uniprot/E3N435 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_010704 ^@ http://purl.uniprot.org/uniprot/E3LWZ4 ^@ Subcellular Location Annotation ^@ Chromosome|||Nucleus http://togogenome.org/gene/31234:GCK72_017605 ^@ http://purl.uniprot.org/uniprot/E3LTU2 ^@ Similarity ^@ Belongs to the peptidase S8 family. Furin subfamily. http://togogenome.org/gene/31234:GCK72_001237 ^@ http://purl.uniprot.org/uniprot/E3LXK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the endophilin family.|||Membrane http://togogenome.org/gene/31234:GCK72_000671 ^@ http://purl.uniprot.org/uniprot/E3M373 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit C family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_025624 ^@ http://purl.uniprot.org/uniprot/E3MC68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FARP (FMRFamide related peptide) family.|||Secreted http://togogenome.org/gene/31234:GCK72_010161 ^@ http://purl.uniprot.org/uniprot/E3MI27 ^@ Similarity ^@ Belongs to the CutC family. http://togogenome.org/gene/31234:GCK72_008485 ^@ http://purl.uniprot.org/uniprot/E3MY10 ^@ Domain|||Similarity ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family. http://togogenome.org/gene/31234:GCK72_023526 ^@ http://purl.uniprot.org/uniprot/E3MMN1 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.|||In the C-terminal section; belongs to the MoeA family.|||In the N-terminal section; belongs to the MoaB/Mog family. http://togogenome.org/gene/31234:GCK72_020668 ^@ http://purl.uniprot.org/uniprot/E3N105 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_014705 ^@ http://purl.uniprot.org/uniprot/E3M6T7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_018884 ^@ http://purl.uniprot.org/uniprot/E3LK38 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_003906 ^@ http://purl.uniprot.org/uniprot/E3MU34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_009750 ^@ http://purl.uniprot.org/uniprot/E3LT40 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL18 family. http://togogenome.org/gene/31234:GCK72_025646 ^@ http://purl.uniprot.org/uniprot/E3MC48 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with an ATP-specific beta subunit, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with a GTP-specific beta subunit forms a GDP-forming succinyl-CoA synthetase (G-SCS).|||Mitochondrion|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. http://togogenome.org/gene/31234:GCK72_005091 ^@ http://purl.uniprot.org/uniprot/E3LGU3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/31234:GCK72_023752 ^@ http://purl.uniprot.org/uniprot/E3M2V6 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/31234:GCK72_010834 ^@ http://purl.uniprot.org/uniprot/E3LWK3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP family.|||Membrane|||Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. http://togogenome.org/gene/31234:GCK72_016975 ^@ http://purl.uniprot.org/uniprot/E3MHD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_025539 ^@ http://purl.uniprot.org/uniprot/E3MCE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS7 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/31234:GCK72_025653 ^@ http://purl.uniprot.org/uniprot/E3MC42 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_003430 ^@ http://purl.uniprot.org/uniprot/E3N2P3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-6 family.|||Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. Involved in miRNA-mediated gene silencing.|||Cytoplasm|||Monomer. Associates with the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/31234:GCK72_013677 ^@ http://purl.uniprot.org/uniprot/E3MS93 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. http://togogenome.org/gene/31234:GCK72_016381 ^@ http://purl.uniprot.org/uniprot/E3MQQ1 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/31234:GCK72_001392 ^@ http://purl.uniprot.org/uniprot/E3MFK2 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/31234:GCK72_001177 ^@ http://purl.uniprot.org/uniprot/E3LXS5 ^@ Similarity ^@ Belongs to the AATF family. http://togogenome.org/gene/31234:GCK72_005912 ^@ http://purl.uniprot.org/uniprot/A8VT33|||http://purl.uniprot.org/uniprot/E3M4A3 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_021307 ^@ http://purl.uniprot.org/uniprot/E3N587 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_016248 ^@ http://purl.uniprot.org/uniprot/E3NJ88 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_000920 ^@ http://purl.uniprot.org/uniprot/E3MYG1 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_001180 ^@ http://purl.uniprot.org/uniprot/E3LXS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Catalyzes the transfer of galactose onto proteins or lipids.|||Membrane http://togogenome.org/gene/31234:GCK72_000996 ^@ http://purl.uniprot.org/uniprot/E3LYA0 ^@ Similarity ^@ Belongs to the MYST (SAS/MOZ) family. http://togogenome.org/gene/31234:GCK72_001065 ^@ http://purl.uniprot.org/uniprot/E3LY35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TORC family.|||Nucleus http://togogenome.org/gene/31234:GCK72_005812 ^@ http://purl.uniprot.org/uniprot/E3M3Z5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_022902 ^@ http://purl.uniprot.org/uniprot/E3MLP3 ^@ Caution|||Similarity ^@ Belongs to the nematode receptor-like protein srg family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_008787 ^@ http://purl.uniprot.org/uniprot/E3M8J1 ^@ Similarity ^@ Belongs to the WD repeat SEC13 family. http://togogenome.org/gene/31234:GCK72_002756 ^@ http://purl.uniprot.org/uniprot/E3LKF8 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_008385 ^@ http://purl.uniprot.org/uniprot/E3NF06 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/31234:GCK72_020806 ^@ http://purl.uniprot.org/uniprot/E3MBR0 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/31234:GCK72_023559 ^@ http://purl.uniprot.org/uniprot/E3M2R7 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/31234:GCK72_009498 ^@ http://purl.uniprot.org/uniprot/E3LS89 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_012880 ^@ http://purl.uniprot.org/uniprot/E3NSA1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS7 family. http://togogenome.org/gene/31234:GCK72_024006 ^@ http://purl.uniprot.org/uniprot/E3LCS0 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/31234:GCK72_021309 ^@ http://purl.uniprot.org/uniprot/E3N585 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_016434 ^@ http://purl.uniprot.org/uniprot/E3MQU8 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_002627 ^@ http://purl.uniprot.org/uniprot/E3LVB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_012272 ^@ http://purl.uniprot.org/uniprot/E3N3S1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_025423 ^@ http://purl.uniprot.org/uniprot/E3MJK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/PBX homeobox family.|||Nucleus http://togogenome.org/gene/31234:GCK72_017289 ^@ http://purl.uniprot.org/uniprot/E3N1R1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_018045 ^@ http://purl.uniprot.org/uniprot/E3LPK3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OST5 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/31234:GCK72_006080 ^@ http://purl.uniprot.org/uniprot/E3M4S3 ^@ Similarity ^@ Belongs to the CCDC53 family. http://togogenome.org/gene/31234:GCK72_014062 ^@ http://purl.uniprot.org/uniprot/E3NQW7 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/31234:GCK72_005846 ^@ http://purl.uniprot.org/uniprot/E3M435 ^@ Function|||Similarity ^@ Belongs to the diphosphomevalonate decarboxylase family.|||Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis. http://togogenome.org/gene/31234:GCK72_021946 ^@ http://purl.uniprot.org/uniprot/E3MEZ7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_013537 ^@ http://purl.uniprot.org/uniprot/E3MR38 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 30 family. http://togogenome.org/gene/31234:GCK72_010355 ^@ http://purl.uniprot.org/uniprot/E3LYI4 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_023386 ^@ http://purl.uniprot.org/uniprot/E3MB58 ^@ Similarity ^@ Belongs to the MYST (SAS/MOZ) family. http://togogenome.org/gene/31234:GCK72_023736 ^@ http://purl.uniprot.org/uniprot/E3M2S1 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_000468 ^@ http://purl.uniprot.org/uniprot/E3MX16 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/31234:GCK72_017379 ^@ http://purl.uniprot.org/uniprot/E3NCK3 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Fibrillarin family. http://togogenome.org/gene/31234:GCK72_004468 ^@ http://purl.uniprot.org/uniprot/E3MRX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMCO4 family.|||Membrane http://togogenome.org/gene/31234:GCK72_008496 ^@ http://purl.uniprot.org/uniprot/E3MXY9 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_001558 ^@ http://purl.uniprot.org/uniprot/E3N1I3 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/31234:GCK72_014048 ^@ http://purl.uniprot.org/uniprot/E3M7N4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATG7 family.|||Cytoplasm|||E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.|||Homodimer.|||Preautophagosomal structure http://togogenome.org/gene/31234:GCK72_001141 ^@ http://purl.uniprot.org/uniprot/E3LXW3 ^@ Similarity ^@ Belongs to the TUB family. http://togogenome.org/gene/31234:GCK72_024037 ^@ http://purl.uniprot.org/uniprot/E3LCP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase inhibitor family.|||Mitochondrion|||Thought to be a regulatory component of the ATP-synthesizing complex in the mitochondria. http://togogenome.org/gene/31234:GCK72_014272 ^@ http://purl.uniprot.org/uniprot/E3MT03 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL34 family. http://togogenome.org/gene/31234:GCK72_002049 ^@ http://purl.uniprot.org/uniprot/E3LM94 ^@ Similarity ^@ Belongs to the Mo25 family. http://togogenome.org/gene/31234:GCK72_006264 ^@ http://purl.uniprot.org/uniprot/E3LR36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/31234:GCK72_024550 ^@ http://purl.uniprot.org/uniprot/E3LDL7 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_009549 ^@ http://purl.uniprot.org/uniprot/E3LS35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_025982 ^@ http://purl.uniprot.org/uniprot/E3MV63 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_014792 ^@ http://purl.uniprot.org/uniprot/E3NTZ0 ^@ Caution|||Function|||Similarity ^@ Belongs to the acetyltransferase ATAT1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically acetylates 'Lys-40' in alpha-tubulin/mec-12 on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for the maintenance of touch receptor neurons and possibly other type of neurons involved in locomotion. http://togogenome.org/gene/31234:GCK72_023692 ^@ http://purl.uniprot.org/uniprot/E3M2K4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_002173 ^@ http://purl.uniprot.org/uniprot/E3MG80 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_016951 ^@ http://purl.uniprot.org/uniprot/E3MHB5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010981 ^@ http://purl.uniprot.org/uniprot/E3LX74 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_019263 ^@ http://purl.uniprot.org/uniprot/E3LJM6 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/31234:GCK72_009417 ^@ http://purl.uniprot.org/uniprot/E3LSH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_014503 ^@ http://purl.uniprot.org/uniprot/E3M6C7 ^@ Similarity ^@ Belongs to the alkB family. http://togogenome.org/gene/31234:GCK72_016989 ^@ http://purl.uniprot.org/uniprot/E3MD46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter. http://togogenome.org/gene/31234:GCK72_005290 ^@ http://purl.uniprot.org/uniprot/E3LF37 ^@ Similarity ^@ Belongs to the dymeclin family. http://togogenome.org/gene/31234:GCK72_006392 ^@ http://purl.uniprot.org/uniprot/E3LQP7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/31234:GCK72_013443 ^@ http://purl.uniprot.org/uniprot/E3NRN4 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/31234:GCK72_010230 ^@ http://purl.uniprot.org/uniprot/E3MIC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TM2 family.|||Membrane http://togogenome.org/gene/31234:GCK72_016290 ^@ http://purl.uniprot.org/uniprot/E3MYC5 ^@ Similarity ^@ Belongs to the synapsin family. http://togogenome.org/gene/31234:GCK72_004942 ^@ http://purl.uniprot.org/uniprot/E3LGF5 ^@ Function|||PTM|||Similarity ^@ Belongs to the eIF-5A family.|||Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. http://togogenome.org/gene/31234:GCK72_017121 ^@ http://purl.uniprot.org/uniprot/E3NKL9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_000835 ^@ http://purl.uniprot.org/uniprot/E3M3M1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB7 subunit family.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/31234:GCK72_007790 ^@ http://purl.uniprot.org/uniprot/E3M9S9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_011786 ^@ http://purl.uniprot.org/uniprot/E3MSM1 ^@ Similarity ^@ Belongs to the TACO1 family. http://togogenome.org/gene/31234:GCK72_013815 ^@ http://purl.uniprot.org/uniprot/E3NE97 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/31234:GCK72_016448 ^@ http://purl.uniprot.org/uniprot/E3MQV8 ^@ Caution|||Similarity ^@ Belongs to the nematode receptor-like protein srg family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_010607 ^@ http://purl.uniprot.org/uniprot/E3LYX2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/31234:GCK72_002577 ^@ http://purl.uniprot.org/uniprot/E3LVG5 ^@ Similarity ^@ Belongs to the TENT family. http://togogenome.org/gene/31234:GCK72_005645 ^@ http://purl.uniprot.org/uniprot/E3LG47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB2 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_005308 ^@ http://purl.uniprot.org/uniprot/E3LF55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Integrator subunit 7 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_009897 ^@ http://purl.uniprot.org/uniprot/E3LSQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_013501 ^@ http://purl.uniprot.org/uniprot/E3MR70 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_014990 ^@ http://purl.uniprot.org/uniprot/E3NKA8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_013263 ^@ http://purl.uniprot.org/uniprot/E3MRL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the caveolin family.|||Cell membrane|||Golgi apparatus membrane|||May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.|||Membrane|||caveola http://togogenome.org/gene/31234:GCK72_001331 ^@ http://purl.uniprot.org/uniprot/E3LXA5 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/31234:GCK72_000813 ^@ http://purl.uniprot.org/uniprot/E3M3J9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-II family.|||Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_016377 ^@ http://purl.uniprot.org/uniprot/E3MQP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat striatin family.|||Membrane http://togogenome.org/gene/31234:GCK72_009107 ^@ http://purl.uniprot.org/uniprot/E3MKS5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/31234:GCK72_005501 ^@ http://purl.uniprot.org/uniprot/E3LFP3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the deoxyhypusine hydroxylase family.|||Binds 2 Fe(2+) ions per subunit.|||Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. http://togogenome.org/gene/31234:GCK72_001175 ^@ http://purl.uniprot.org/uniprot/E3LXS7 ^@ Similarity ^@ Belongs to the complexin/synaphin family. http://togogenome.org/gene/31234:GCK72_024826 ^@ http://purl.uniprot.org/uniprot/E3LCL1 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/31234:GCK72_010242 ^@ http://purl.uniprot.org/uniprot/E3MIE1 ^@ Similarity ^@ Belongs to the STEEP1 family. http://togogenome.org/gene/31234:GCK72_017719 ^@ http://purl.uniprot.org/uniprot/E3LU65 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_005417 ^@ http://purl.uniprot.org/uniprot/E3LFF7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I 51 kDa subunit family.|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_013911 ^@ http://purl.uniprot.org/uniprot/E3M791 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS8 family. http://togogenome.org/gene/31234:GCK72_000064 ^@ http://purl.uniprot.org/uniprot/E3N7P0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_004798 ^@ http://purl.uniprot.org/uniprot/E3MZV4 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_000048 ^@ http://purl.uniprot.org/uniprot/E3MT45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SCC4/mau-2 family.|||nucleoplasm http://togogenome.org/gene/31234:GCK72_001956 ^@ http://purl.uniprot.org/uniprot/E3LMJ8 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/31234:GCK72_019897 ^@ http://purl.uniprot.org/uniprot/E3LJF2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_019116 ^@ http://purl.uniprot.org/uniprot/E3LKP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 14 family. XylT subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_019939 ^@ http://purl.uniprot.org/uniprot/E3LJK5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_010229 ^@ http://purl.uniprot.org/uniprot/E3MIC6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/31234:GCK72_006701 ^@ http://purl.uniprot.org/uniprot/E3M143 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_000220 ^@ http://purl.uniprot.org/uniprot/E3NGZ2 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_006739 ^@ http://purl.uniprot.org/uniprot/E3M0X8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_017568 ^@ http://purl.uniprot.org/uniprot/E3LTQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_000631 ^@ http://purl.uniprot.org/uniprot/E3M334 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_002130 ^@ http://purl.uniprot.org/uniprot/E3LM09 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Mitochondrion|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.|||nucleolus|||nucleoplasm http://togogenome.org/gene/31234:GCK72_010853 ^@ http://purl.uniprot.org/uniprot/E3LWI4 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_001045 ^@ http://purl.uniprot.org/uniprot/E3LY57 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.|||GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.|||nucleolus http://togogenome.org/gene/31234:GCK72_017336 ^@ http://purl.uniprot.org/uniprot/E3NKR5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter. http://togogenome.org/gene/31234:GCK72_023532 ^@ http://purl.uniprot.org/uniprot/E3MMM5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_005442 ^@ http://purl.uniprot.org/uniprot/E3LFH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes small subunit family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. http://togogenome.org/gene/31234:GCK72_000873 ^@ http://purl.uniprot.org/uniprot/E3N4S0 ^@ Similarity ^@ Belongs to the GST superfamily. Zeta family. http://togogenome.org/gene/31234:GCK72_017474 ^@ http://purl.uniprot.org/uniprot/E3MND7 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/31234:GCK72_018478 ^@ http://purl.uniprot.org/uniprot/E3LP06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Late endosome membrane|||Membrane http://togogenome.org/gene/31234:GCK72_009110 ^@ http://purl.uniprot.org/uniprot/E3MKS8 ^@ Function|||Similarity ^@ Belongs to the UFM1 family.|||Ubiquitin-like modifier. http://togogenome.org/gene/31234:GCK72_013528 ^@ http://purl.uniprot.org/uniprot/E3NRT0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/31234:GCK72_009632 ^@ http://purl.uniprot.org/uniprot/E3LRV2 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/31234:GCK72_022035 ^@ http://purl.uniprot.org/uniprot/E3NB50 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_014470 ^@ http://purl.uniprot.org/uniprot/E3M6G0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_013220 ^@ http://purl.uniprot.org/uniprot/E3NRV4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_006814 ^@ http://purl.uniprot.org/uniprot/E3M1Y6 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/31234:GCK72_017989 ^@ http://purl.uniprot.org/uniprot/E3LTH3 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/31234:GCK72_001724 ^@ http://purl.uniprot.org/uniprot/E3LN36 ^@ Similarity ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. http://togogenome.org/gene/31234:GCK72_010622 ^@ http://purl.uniprot.org/uniprot/E3LYW0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_009617 ^@ http://purl.uniprot.org/uniprot/E3LRW5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_004244 ^@ http://purl.uniprot.org/uniprot/E3MQ17 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_008458 ^@ http://purl.uniprot.org/uniprot/E3MY48 ^@ Similarity ^@ Belongs to the IPP transferase family. http://togogenome.org/gene/31234:GCK72_018614 ^@ http://purl.uniprot.org/uniprot/E3M0A4 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_002347 ^@ http://purl.uniprot.org/uniprot/E3LUW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicastrin family.|||Membrane http://togogenome.org/gene/31234:GCK72_014706 ^@ http://purl.uniprot.org/uniprot/E3M6T5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_006619 ^@ http://purl.uniprot.org/uniprot/E3LRJ7 ^@ Similarity ^@ Belongs to the BORA family. http://togogenome.org/gene/31234:GCK72_013686 ^@ http://purl.uniprot.org/uniprot/E3MS82 ^@ Subcellular Location Annotation ^@ Membrane|||dendrite http://togogenome.org/gene/31234:GCK72_014208 ^@ http://purl.uniprot.org/uniprot/E3MSU0 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/31234:GCK72_019041 ^@ http://purl.uniprot.org/uniprot/E3LKA1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_000152 ^@ http://purl.uniprot.org/uniprot/E3NE14 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/31234:GCK72_000715 ^@ http://purl.uniprot.org/uniprot/E3M3B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_005166 ^@ http://purl.uniprot.org/uniprot/E3LH16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FARP (FMRFamide related peptide) family.|||Secreted http://togogenome.org/gene/31234:GCK72_003637 ^@ http://purl.uniprot.org/uniprot/E3NAT6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_005103 ^@ http://purl.uniprot.org/uniprot/E3LGV5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/31234:GCK72_006768 ^@ http://purl.uniprot.org/uniprot/E3M0V0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGW family.|||Endoplasmic reticulum membrane|||Membrane|||Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. http://togogenome.org/gene/31234:GCK72_005204 ^@ http://purl.uniprot.org/uniprot/E3LH54 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase A2 family.|||Binds 1 Ca(2+) ion per subunit.|||Secreted http://togogenome.org/gene/31234:GCK72_025656 ^@ http://purl.uniprot.org/uniprot/E3MC37 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the calsequestrin family.|||Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.|||Sarcoplasmic reticulum lumen http://togogenome.org/gene/31234:GCK72_008189 ^@ http://purl.uniprot.org/uniprot/E3MNS4 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/31234:GCK72_000141 ^@ http://purl.uniprot.org/uniprot/E3N469 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/31234:GCK72_022869 ^@ http://purl.uniprot.org/uniprot/E3MLL1 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srg family. http://togogenome.org/gene/31234:GCK72_024856 ^@ http://purl.uniprot.org/uniprot/E3LCC5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/31234:GCK72_000395 ^@ http://purl.uniprot.org/uniprot/E3N7Q6 ^@ Similarity ^@ Belongs to the PDCD5 family. http://togogenome.org/gene/31234:GCK72_013527 ^@ http://purl.uniprot.org/uniprot/E3MR48 ^@ Similarity ^@ Belongs to the SNAPIN family. http://togogenome.org/gene/31234:GCK72_011914 ^@ http://purl.uniprot.org/uniprot/E3MLC6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_013549 ^@ http://purl.uniprot.org/uniprot/E3MR24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/31234:GCK72_017607 ^@ http://purl.uniprot.org/uniprot/E3LTU3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_024678 ^@ http://purl.uniprot.org/uniprot/E3LD81 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. http://togogenome.org/gene/31234:GCK72_000663 ^@ http://purl.uniprot.org/uniprot/E3M362 ^@ Similarity ^@ Belongs to the argonaute family. http://togogenome.org/gene/31234:GCK72_019128 ^@ http://purl.uniprot.org/uniprot/E3LKQ1 ^@ Caution|||Cofactor|||Function|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Metalloprotease.|||Secreted http://togogenome.org/gene/31234:GCK72_014522 ^@ http://purl.uniprot.org/uniprot/E3M6A6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_001076 ^@ http://purl.uniprot.org/uniprot/E3LY25 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/31234:GCK72_009548 ^@ http://purl.uniprot.org/uniprot/E3LS36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_020901 ^@ http://purl.uniprot.org/uniprot/E3MBD7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_023223 ^@ http://purl.uniprot.org/uniprot/E3MAP2 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/31234:GCK72_008379 ^@ http://purl.uniprot.org/uniprot/E3NEZ9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat LIS1/nudF family.|||Dimerization mediated by the LisH domain may be required to activate dynein.|||May be a component of a dynein regulatory complex composed of at least lis-1 and nud-2. Interacts with nud-2.|||Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes.|||centrosome|||cytoskeleton http://togogenome.org/gene/31234:GCK72_006378 ^@ http://purl.uniprot.org/uniprot/E3LQR3 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/31234:GCK72_016096 ^@ http://purl.uniprot.org/uniprot/E3N9W0 ^@ Subcellular Location Annotation ^@ cilium basal body http://togogenome.org/gene/31234:GCK72_014001 ^@ http://purl.uniprot.org/uniprot/E3M7I3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uS3 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_018220 ^@ http://purl.uniprot.org/uniprot/E3LQ23 ^@ Caution|||Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_014843 ^@ http://purl.uniprot.org/uniprot/E3M528 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_011286 ^@ http://purl.uniprot.org/uniprot/E3NJN3 ^@ Subcellular Location Annotation ^@ cilium basal body http://togogenome.org/gene/31234:GCK72_004677 ^@ http://purl.uniprot.org/uniprot/E3MHZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lin-7 family.|||Cell junction|||Cell membrane|||Membrane|||Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. http://togogenome.org/gene/31234:GCK72_024296 ^@ http://purl.uniprot.org/uniprot/E3LED8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_013656 ^@ http://purl.uniprot.org/uniprot/E3MSB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_017935 ^@ http://purl.uniprot.org/uniprot/E3LUU0 ^@ Similarity ^@ In the N-terminal section; belongs to the MoaB/Mog family. http://togogenome.org/gene/31234:GCK72_017906 ^@ http://purl.uniprot.org/uniprot/E3LUQ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_006407 ^@ http://purl.uniprot.org/uniprot/E3LQM5 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/31234:GCK72_014278 ^@ http://purl.uniprot.org/uniprot/E3MT08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_010449 ^@ http://purl.uniprot.org/uniprot/E3LZD7 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/31234:GCK72_025795 ^@ http://purl.uniprot.org/uniprot/E3ME64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Membrane http://togogenome.org/gene/31234:GCK72_005473 ^@ http://purl.uniprot.org/uniprot/E3LFK9 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_003685 ^@ http://purl.uniprot.org/uniprot/E3LQ92 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_025626 ^@ http://purl.uniprot.org/uniprot/E3MC66 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_014907 ^@ http://purl.uniprot.org/uniprot/E3NQ57 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/31234:GCK72_010343 ^@ http://purl.uniprot.org/uniprot/E3LYJ9 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_020894 ^@ http://purl.uniprot.org/uniprot/E3MBE4 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_001338 ^@ http://purl.uniprot.org/uniprot/E3LX99 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/31234:GCK72_015397 ^@ http://purl.uniprot.org/uniprot/E3NIW3 ^@ Function|||Similarity|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.|||Belongs to the complex I NDUFV3 subunit family.|||Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme. http://togogenome.org/gene/31234:GCK72_005385 ^@ http://purl.uniprot.org/uniprot/E3LFC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FUN14 family.|||Mitochondrion outer membrane http://togogenome.org/gene/31234:GCK72_000861 ^@ http://purl.uniprot.org/uniprot/E3N4Q9 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/31234:GCK72_020615 ^@ http://purl.uniprot.org/uniprot/E3NEK1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010831 ^@ http://purl.uniprot.org/uniprot/E3LWK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_013286 ^@ http://purl.uniprot.org/uniprot/E3NNU7 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/31234:GCK72_006265 ^@ http://purl.uniprot.org/uniprot/E3LR35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/31234:GCK72_023292 ^@ http://purl.uniprot.org/uniprot/E3MAW6 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/31234:GCK72_018705 ^@ http://purl.uniprot.org/uniprot/E3M0K8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SWEET sugar transporter family.|||Cell membrane|||Golgi apparatus membrane|||Mediates sugar transport across membranes.|||Membrane http://togogenome.org/gene/31234:GCK72_016055 ^@ http://purl.uniprot.org/uniprot/E3NDB4 ^@ Similarity ^@ Belongs to the selenoprotein M/F family. http://togogenome.org/gene/31234:GCK72_002453 ^@ http://purl.uniprot.org/uniprot/E3LVU7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_008702 ^@ http://purl.uniprot.org/uniprot/E3M8A6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GOSR1 family.|||Component of several multiprotein Golgi SNARE complexes.|||Golgi apparatus membrane|||Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.|||Membrane http://togogenome.org/gene/31234:GCK72_018804 ^@ http://purl.uniprot.org/uniprot/E3LZP0 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/31234:GCK72_008826 ^@ http://purl.uniprot.org/uniprot/E3M8G2 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. METL family.|||S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/31234:GCK72_013130 ^@ http://purl.uniprot.org/uniprot/E3NVK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the THOC7 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_015929 ^@ http://purl.uniprot.org/uniprot/E3NEV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CLUAP1 family.|||cilium http://togogenome.org/gene/31234:GCK72_017723 ^@ http://purl.uniprot.org/uniprot/E3LU69 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_011811 ^@ http://purl.uniprot.org/uniprot/E3MSP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SPT4 family.|||Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.|||Nucleus http://togogenome.org/gene/31234:GCK72_006220 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_016040 ^@ http://purl.uniprot.org/uniprot/E3NDD3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).|||Cytoplasm|||Endoplasmic reticulum|||The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.|||The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER. http://togogenome.org/gene/31234:GCK72_001173 ^@ http://purl.uniprot.org/uniprot/E3LXS9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATG5 family.|||Conjugated with atg-12.|||Involved in autophagic vesicle formation.|||Preautophagosomal structure membrane http://togogenome.org/gene/31234:GCK72_001128 ^@ http://purl.uniprot.org/uniprot/E3LXX6 ^@ Caution|||Similarity ^@ Belongs to the semaphorin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_010920 ^@ http://purl.uniprot.org/uniprot/E3LWA6 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/31234:GCK72_006008 ^@ http://purl.uniprot.org/uniprot/E3M4K3 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/31234:GCK72_018562 ^@ http://purl.uniprot.org/uniprot/E3LP93 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/31234:GCK72_001233 ^@ http://purl.uniprot.org/uniprot/E3LXL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Late endosome membrane|||Membrane http://togogenome.org/gene/31234:GCK72_005890 ^@ http://purl.uniprot.org/uniprot/E3M482 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRI3 family.|||Membrane|||perinuclear region http://togogenome.org/gene/31234:GCK72_018363 ^@ http://purl.uniprot.org/uniprot/E3LNP2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_019298 ^@ http://purl.uniprot.org/uniprot/E3LJW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF10 family.|||Nucleus|||The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. http://togogenome.org/gene/31234:GCK72_013481 ^@ http://purl.uniprot.org/uniprot/E3MR98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.|||Membrane http://togogenome.org/gene/31234:GCK72_000406 ^@ http://purl.uniprot.org/uniprot/E3N7R8 ^@ Similarity ^@ Belongs to the taxilin family. http://togogenome.org/gene/31234:GCK72_009880 ^@ http://purl.uniprot.org/uniprot/E3LSS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat TRM82 family.|||Forms a heterodimer with the catalytic subunit.|||Nucleus|||Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. http://togogenome.org/gene/31234:GCK72_007988 ^@ http://purl.uniprot.org/uniprot/E3MDE4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_000545 ^@ http://purl.uniprot.org/uniprot/E3M3S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_015768 ^@ http://purl.uniprot.org/uniprot/E3NJ23 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_014331 ^@ http://purl.uniprot.org/uniprot/E3MM88 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/31234:GCK72_010448 ^@ http://purl.uniprot.org/uniprot/E3LZD8 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_008144 ^@ http://purl.uniprot.org/uniprot/E3MDF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL41 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_003591 ^@ http://purl.uniprot.org/uniprot/E3M8Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 23 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_017772 ^@ http://purl.uniprot.org/uniprot/E3LUC3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GOSR2 family.|||Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.|||Membrane http://togogenome.org/gene/31234:GCK72_005227 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_014372 ^@ http://purl.uniprot.org/uniprot/E3MM31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/31234:GCK72_017690 ^@ http://purl.uniprot.org/uniprot/E3LU33 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the kinesin light chain family.|||Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.|||Oligomeric complex composed of two heavy chains and two light chains.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_000853 ^@ http://purl.uniprot.org/uniprot/E3N4Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCF/LEF family.|||Nucleus http://togogenome.org/gene/31234:GCK72_013844 ^@ http://purl.uniprot.org/uniprot/E3M726 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS4 family. http://togogenome.org/gene/31234:GCK72_006461 ^@ http://purl.uniprot.org/uniprot/E3LQG9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/31234:GCK72_009996 ^@ http://purl.uniprot.org/uniprot/E3MCN4 ^@ Similarity ^@ Belongs to the EMC7 family. http://togogenome.org/gene/31234:GCK72_022169 ^@ http://purl.uniprot.org/uniprot/E3MAB0 ^@ Similarity ^@ Belongs to the GTR/RAG GTP-binding protein family. http://togogenome.org/gene/31234:GCK72_001463 ^@ http://purl.uniprot.org/uniprot/E3MFC1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/31234:GCK72_015178 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_007133 ^@ http://purl.uniprot.org/uniprot/E3MVF4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/31234:GCK72_009882 ^@ http://purl.uniprot.org/uniprot/E3LSS3 ^@ Similarity ^@ Belongs to the ODR-4 family. http://togogenome.org/gene/31234:GCK72_018999 ^@ http://purl.uniprot.org/uniprot/E3LZY7 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/31234:GCK72_024402 ^@ http://purl.uniprot.org/uniprot/E3LE30 ^@ Similarity ^@ Belongs to the GPSM family. http://togogenome.org/gene/31234:GCK72_022032 ^@ http://purl.uniprot.org/uniprot/E3NB60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HIT family.|||Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.|||Nucleus http://togogenome.org/gene/31234:GCK72_019973 ^@ http://purl.uniprot.org/uniprot/E3LHA2 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/31234:GCK72_000343 ^@ http://purl.uniprot.org/uniprot/E3NLR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP31 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_025305 ^@ http://purl.uniprot.org/uniprot/E3MUB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XK family.|||Membrane http://togogenome.org/gene/31234:GCK72_015063 ^@ http://purl.uniprot.org/uniprot/E3M5T5 ^@ Caution|||Similarity ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_014154 ^@ http://purl.uniprot.org/uniprot/E3M7Z9 ^@ Similarity ^@ Belongs to the cuticular collagen family. http://togogenome.org/gene/31234:GCK72_014930 ^@ http://purl.uniprot.org/uniprot/E3M5B9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_019901 ^@ http://purl.uniprot.org/uniprot/E3LJF7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_006587 ^@ http://purl.uniprot.org/uniprot/E3LRN2 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. http://togogenome.org/gene/31234:GCK72_008050 ^@ http://purl.uniprot.org/uniprot/E3MDQ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC2 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. http://togogenome.org/gene/31234:GCK72_024075 ^@ http://purl.uniprot.org/uniprot/E3LCF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_016575 ^@ http://purl.uniprot.org/uniprot/E3MTU8 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/31234:GCK72_000945 ^@ http://purl.uniprot.org/uniprot/E3MYI5 ^@ Similarity ^@ Belongs to the FBPase class 1 family. http://togogenome.org/gene/31234:GCK72_023250 ^@ http://purl.uniprot.org/uniprot/E3MAS2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/31234:GCK72_014976 ^@ http://purl.uniprot.org/uniprot/E3M5I2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_018801 ^@ http://purl.uniprot.org/uniprot/E3LZN8 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/31234:GCK72_010726 ^@ http://purl.uniprot.org/uniprot/E3LWX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I LYR family.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_017214 ^@ http://purl.uniprot.org/uniprot/E3N519 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_026148 ^@ http://purl.uniprot.org/uniprot/E3MPI4 ^@ Similarity ^@ Belongs to the argonaute family. http://togogenome.org/gene/31234:GCK72_014753 ^@ http://purl.uniprot.org/uniprot/E3M6N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptophysin/synaptobrevin family.|||Membrane http://togogenome.org/gene/31234:GCK72_003606 ^@ http://purl.uniprot.org/uniprot/E3M910 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/31234:GCK72_005924 ^@ http://purl.uniprot.org/uniprot/E3M4B6 ^@ Similarity ^@ Belongs to the MMACHC family. http://togogenome.org/gene/31234:GCK72_015935 ^@ http://purl.uniprot.org/uniprot/E3NGV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM144 family.|||Membrane http://togogenome.org/gene/31234:GCK72_014849 ^@ http://purl.uniprot.org/uniprot/E3M534 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_003577 ^@ http://purl.uniprot.org/uniprot/E3M8Y1 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/31234:GCK72_008401 ^@ http://purl.uniprot.org/uniprot/E3NF16 ^@ Caution|||Cofactor ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_024207 ^@ http://purl.uniprot.org/uniprot/E3LEM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits. http://togogenome.org/gene/31234:GCK72_018320 ^@ http://purl.uniprot.org/uniprot/E3LNJ6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS11 family. http://togogenome.org/gene/31234:GCK72_005565 ^@ http://purl.uniprot.org/uniprot/E3LFW1 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/31234:GCK72_001416 ^@ http://purl.uniprot.org/uniprot/E3MFG7 ^@ Similarity ^@ Belongs to the LplA family. http://togogenome.org/gene/31234:GCK72_003851 ^@ http://purl.uniprot.org/uniprot/E3NJA1 ^@ Similarity ^@ Belongs to the glutaminase family. http://togogenome.org/gene/31234:GCK72_019967 ^@ http://purl.uniprot.org/uniprot/E3LH97 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_018050 ^@ http://purl.uniprot.org/uniprot/E3LPK8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_014045 ^@ http://purl.uniprot.org/uniprot/E3M7N1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_011637 ^@ http://purl.uniprot.org/uniprot/E3MNJ3 ^@ Similarity ^@ Belongs to the GroES chaperonin family. http://togogenome.org/gene/31234:GCK72_024847 ^@ http://purl.uniprot.org/uniprot/E3LCI6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_004284 ^@ http://purl.uniprot.org/uniprot/E3NFS4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARV1 family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.|||Membrane http://togogenome.org/gene/31234:GCK72_008250 ^@ http://purl.uniprot.org/uniprot/E3MG32 ^@ Similarity ^@ Belongs to the Iojap/RsfS family. http://togogenome.org/gene/31234:GCK72_008928 ^@ http://purl.uniprot.org/uniprot/E3N6K8 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/31234:GCK72_013958 ^@ http://purl.uniprot.org/uniprot/E3M7E0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOSIP family.|||Nucleus http://togogenome.org/gene/31234:GCK72_018192 ^@ http://purl.uniprot.org/uniprot/E3LPZ5 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/31234:GCK72_018145 ^@ http://purl.uniprot.org/uniprot/C6SUP7 ^@ Subcellular Location Annotation|||Subunit ^@ Heterodimer of burs and pburs.|||Secreted http://togogenome.org/gene/31234:GCK72_001001 ^@ http://purl.uniprot.org/uniprot/E3LY94 ^@ Subunit ^@ Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/31234:GCK72_000667 ^@ http://purl.uniprot.org/uniprot/E3M367 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_014970 ^@ http://purl.uniprot.org/uniprot/E3NPT2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_006060 ^@ http://purl.uniprot.org/uniprot/E3M4Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_010812 ^@ http://purl.uniprot.org/uniprot/E3LWN3 ^@ Similarity ^@ Belongs to the CDV3 family. http://togogenome.org/gene/31234:GCK72_001976 ^@ http://purl.uniprot.org/uniprot/E3LMH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_011707 ^@ http://purl.uniprot.org/uniprot/E3NCN5 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_010519 ^@ http://purl.uniprot.org/uniprot/E3LZ66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Chromosome|||Nucleus http://togogenome.org/gene/31234:GCK72_004807 ^@ http://purl.uniprot.org/uniprot/E3MZU7 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_021826 ^@ http://purl.uniprot.org/uniprot/E3NIY3 ^@ Similarity ^@ Belongs to the DAMOX/DASOX family. http://togogenome.org/gene/31234:GCK72_009273 ^@ http://purl.uniprot.org/uniprot/E3N098 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_021795 ^@ http://purl.uniprot.org/uniprot/E3NIB3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_006704 ^@ http://purl.uniprot.org/uniprot/E3M139 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_009971 ^@ http://purl.uniprot.org/uniprot/E3MCK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SNF8 family.|||Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.|||Component of the endosomal sorting complex required for transport II (ESCRT-II). http://togogenome.org/gene/31234:GCK72_018218 ^@ http://purl.uniprot.org/uniprot/E3LQ21 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_005724 ^@ http://purl.uniprot.org/uniprot/E3MN08 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/31234:GCK72_024177 ^@ http://purl.uniprot.org/uniprot/E3LEQ1 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/31234:GCK72_005996 ^@ http://purl.uniprot.org/uniprot/E3M4J1 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6. http://togogenome.org/gene/31234:GCK72_017964 ^@ http://purl.uniprot.org/uniprot/E3LTE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_001642 ^@ http://purl.uniprot.org/uniprot/E3LLU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_019591 ^@ http://purl.uniprot.org/uniprot/E3LLL2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/31234:GCK72_024222 ^@ http://purl.uniprot.org/uniprot/E3LEL1 ^@ Similarity ^@ Belongs to the TAF11 family. http://togogenome.org/gene/31234:GCK72_002404 ^@ http://purl.uniprot.org/uniprot/E3LVZ5 ^@ Similarity ^@ Belongs to the EMC8/EMC9 family. http://togogenome.org/gene/31234:GCK72_001181 ^@ http://purl.uniprot.org/uniprot/E3LXS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCDC124 family.|||Midbody http://togogenome.org/gene/31234:GCK72_024501 ^@ http://purl.uniprot.org/uniprot/E3LDS0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_013164 ^@ http://purl.uniprot.org/uniprot/E3NCG8 ^@ Similarity ^@ Belongs to the UPF0375 family. http://togogenome.org/gene/31234:GCK72_014541 ^@ http://purl.uniprot.org/uniprot/E3M685 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC3 family.|||Membrane http://togogenome.org/gene/31234:GCK72_006287 ^@ http://purl.uniprot.org/uniprot/E3LR10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_018697 ^@ http://purl.uniprot.org/uniprot/E3M0K1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_010303 ^@ http://purl.uniprot.org/uniprot/E3LYP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P4HA family.|||Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.|||Endoplasmic reticulum lumen http://togogenome.org/gene/31234:GCK72_001112 ^@ http://purl.uniprot.org/uniprot/E3LXZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF4 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_008589 ^@ http://purl.uniprot.org/uniprot/E3N9G8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/31234:GCK72_018682 ^@ http://purl.uniprot.org/uniprot/E3M0I1 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/31234:GCK72_022041 ^@ http://purl.uniprot.org/uniprot/E3NB66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_005754 ^@ http://purl.uniprot.org/uniprot/E3MMX6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_016081 ^@ http://purl.uniprot.org/uniprot/E3NH76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-gamma family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/31234:GCK72_009640 ^@ http://purl.uniprot.org/uniprot/E3LRU5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10A family.|||Binds 2 Zn(2+) ions per subunit.|||Can bind about 5 Ca(2+) ions per subunit. http://togogenome.org/gene/31234:GCK72_018864 ^@ http://purl.uniprot.org/uniprot/E3LZV3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_013373 ^@ http://purl.uniprot.org/uniprot/E3N5L8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_013547 ^@ http://purl.uniprot.org/uniprot/E3MR26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/31234:GCK72_013655 ^@ http://purl.uniprot.org/uniprot/E3MSC0 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/31234:GCK72_021861 ^@ http://purl.uniprot.org/uniprot/E3MF81 ^@ Similarity ^@ Belongs to the MAPRE family. http://togogenome.org/gene/31234:GCK72_016540 ^@ http://purl.uniprot.org/uniprot/E3MTY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the VPS36 family.|||Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.|||Component of the endosomal sorting complex required for transport II (ESCRT-II).|||Cytoplasm|||Endosome http://togogenome.org/gene/31234:GCK72_009823 ^@ http://purl.uniprot.org/uniprot/E3LSX6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/31234:GCK72_003480 ^@ http://purl.uniprot.org/uniprot/E3M8P2 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/31234:GCK72_024304 ^@ http://purl.uniprot.org/uniprot/E3LEC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_014593 ^@ http://purl.uniprot.org/uniprot/A8IKQ2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/31234:GCK72_001253 ^@ http://purl.uniprot.org/uniprot/E3LXI8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS10 family. http://togogenome.org/gene/31234:GCK72_021932 ^@ http://purl.uniprot.org/uniprot/E3MF12 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/31234:GCK72_001413 ^@ http://purl.uniprot.org/uniprot/E3MFH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_005086 ^@ http://purl.uniprot.org/uniprot/E3LGT9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM138 family.|||Membrane|||Required for ciliogenesis.|||Vacuole membrane http://togogenome.org/gene/31234:GCK72_014410 ^@ http://purl.uniprot.org/uniprot/E3MLZ0 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/31234:GCK72_006681 ^@ http://purl.uniprot.org/uniprot/E3M189 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_022209 ^@ http://purl.uniprot.org/uniprot/E3MA64 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/31234:GCK72_005849 ^@ http://purl.uniprot.org/uniprot/E3M438 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/31234:GCK72_014035 ^@ http://purl.uniprot.org/uniprot/E3M7L9 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_001866 ^@ http://purl.uniprot.org/uniprot/E3LMU2 ^@ Cofactor|||Similarity ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/31234:GCK72_009475 ^@ http://purl.uniprot.org/uniprot/E3LSB3 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/31234:GCK72_003061 ^@ http://purl.uniprot.org/uniprot/E3N004 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.|||Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.|||In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.|||Nucleus http://togogenome.org/gene/31234:GCK72_016749 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_006937 ^@ http://purl.uniprot.org/uniprot/E3M1M4 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_001832 ^@ http://purl.uniprot.org/uniprot/E3LMX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM144 family.|||Membrane http://togogenome.org/gene/31234:GCK72_019229 ^@ http://purl.uniprot.org/uniprot/E3LLD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001051 ^@ http://purl.uniprot.org/uniprot/E3LY51 ^@ Similarity ^@ Belongs to the SDHAF4 family. http://togogenome.org/gene/31234:GCK72_023141 ^@ http://purl.uniprot.org/uniprot/E3MKG2 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/31234:GCK72_017773 ^@ http://purl.uniprot.org/uniprot/E3LUC4 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_023807 ^@ http://purl.uniprot.org/uniprot/E3M259 ^@ Subcellular Location Annotation ^@ adherens junction http://togogenome.org/gene/31234:GCK72_019338 ^@ http://purl.uniprot.org/uniprot/E3LK23 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/31234:GCK72_017124 ^@ http://purl.uniprot.org/uniprot/E3LKS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_005250 ^@ http://purl.uniprot.org/uniprot/E3LEZ6 ^@ Similarity ^@ Belongs to the UPF0729 family. http://togogenome.org/gene/31234:GCK72_013734 ^@ http://purl.uniprot.org/uniprot/E3N402 ^@ Similarity ^@ Belongs to the helicase family. RLR subfamily. http://togogenome.org/gene/31234:GCK72_020181 ^@ http://purl.uniprot.org/uniprot/E3LHX0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_006227 ^@ http://purl.uniprot.org/uniprot/E3LR77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_001826 ^@ http://purl.uniprot.org/uniprot/E3LMY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM144 family.|||Membrane http://togogenome.org/gene/31234:GCK72_009002 ^@ http://purl.uniprot.org/uniprot/E3MWF8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_019031 ^@ http://purl.uniprot.org/uniprot/E3LK60 ^@ Similarity ^@ Belongs to the MPI phosphatase family. http://togogenome.org/gene/31234:GCK72_003648 ^@ http://purl.uniprot.org/uniprot/E3NAU7 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/31234:GCK72_016054 ^@ http://purl.uniprot.org/uniprot/E3NDB5 ^@ Caution|||Function|||Similarity ^@ Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).|||Belongs to the TDD superfamily. TSR3 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_014423 ^@ http://purl.uniprot.org/uniprot/E3MLX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM144 family.|||Membrane http://togogenome.org/gene/31234:GCK72_005954 ^@ http://purl.uniprot.org/uniprot/E3M4F0 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/31234:GCK72_021587 ^@ http://purl.uniprot.org/uniprot/E3NDM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/31234:GCK72_005201 ^@ http://purl.uniprot.org/uniprot/E3LH50 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_000554 ^@ http://purl.uniprot.org/uniprot/E3M3T0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS19 family. http://togogenome.org/gene/31234:GCK72_022050 ^@ http://purl.uniprot.org/uniprot/E3NB77 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_001074 ^@ http://purl.uniprot.org/uniprot/E3LY26 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/31234:GCK72_001371 ^@ http://purl.uniprot.org/uniprot/E3MFM4 ^@ Similarity ^@ Belongs to the cuticular collagen family. http://togogenome.org/gene/31234:GCK72_025559 ^@ http://purl.uniprot.org/uniprot/E3MCD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_014754 ^@ http://purl.uniprot.org/uniprot/E3M6N2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Cytoplasm|||In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.|||Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. http://togogenome.org/gene/31234:GCK72_024658 ^@ http://purl.uniprot.org/uniprot/E3LDA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase g subunit family.|||Membrane|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. http://togogenome.org/gene/31234:GCK72_020807 ^@ http://purl.uniprot.org/uniprot/E3MBQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SAYP family.|||Nucleus http://togogenome.org/gene/31234:GCK72_009370 ^@ http://purl.uniprot.org/uniprot/E3LSL8 ^@ Similarity ^@ Belongs to the eukaryotic diacylglycerol kinase family. http://togogenome.org/gene/31234:GCK72_012872 ^@ http://purl.uniprot.org/uniprot/E3NC63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rab GDI family.|||Cytoplasm|||Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. http://togogenome.org/gene/31234:GCK72_013329 ^@ http://purl.uniprot.org/uniprot/E3MRD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FARP (FMRFamide related peptide) family.|||Secreted http://togogenome.org/gene/31234:GCK72_003560 ^@ http://purl.uniprot.org/uniprot/E3M8W9 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/31234:GCK72_025729 ^@ http://purl.uniprot.org/uniprot/E3MDZ4 ^@ Similarity ^@ Belongs to the alpha-carbonic anhydrase family. http://togogenome.org/gene/31234:GCK72_013191 ^@ http://purl.uniprot.org/uniprot/E3NIK5 ^@ Function|||Similarity ^@ Belongs to the eIF-1A family.|||Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1. http://togogenome.org/gene/31234:GCK72_001821 ^@ http://purl.uniprot.org/uniprot/E3LMY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_021583 ^@ http://purl.uniprot.org/uniprot/E3NDM2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_001236 ^@ http://purl.uniprot.org/uniprot/E3LXL1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.|||Nucleus http://togogenome.org/gene/31234:GCK72_017871 ^@ http://purl.uniprot.org/uniprot/E3LUM0 ^@ Similarity ^@ Belongs to the calreticulin family. http://togogenome.org/gene/31234:GCK72_019148 ^@ http://purl.uniprot.org/uniprot/E3LKT8 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/31234:GCK72_008762 ^@ http://purl.uniprot.org/uniprot/E3M841 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/31234:GCK72_005457 ^@ http://purl.uniprot.org/uniprot/E3LFJ3 ^@ Similarity ^@ Belongs to the SLBP family. http://togogenome.org/gene/31234:GCK72_022289 ^@ http://purl.uniprot.org/uniprot/E3M9Y0 ^@ Similarity|||Subunit ^@ Homotetramer.|||In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.|||In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. http://togogenome.org/gene/31234:GCK72_007298 ^@ http://purl.uniprot.org/uniprot/E3MJ11 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_006809 ^@ http://purl.uniprot.org/uniprot/E3M1Z3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CNRIP family.|||Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.|||Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. http://togogenome.org/gene/31234:GCK72_005630 ^@ http://purl.uniprot.org/uniprot/E3LG30 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_025613 ^@ http://purl.uniprot.org/uniprot/E3MC80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calcium channel flower family.|||Membrane|||synaptic vesicle membrane http://togogenome.org/gene/31234:GCK72_000913 ^@ http://purl.uniprot.org/uniprot/E3MYF4 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_024587 ^@ http://purl.uniprot.org/uniprot/E3LDI3 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/31234:GCK72_001602 ^@ http://purl.uniprot.org/uniprot/E3LNC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase CarF family.|||Membrane http://togogenome.org/gene/31234:GCK72_017926 ^@ http://purl.uniprot.org/uniprot/E3LUT1 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/31234:GCK72_017708 ^@ http://purl.uniprot.org/uniprot/E3LU49 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_000814 ^@ http://purl.uniprot.org/uniprot/E3M3K0 ^@ Similarity ^@ Belongs to the APC10 family. http://togogenome.org/gene/31234:GCK72_014521 ^@ http://purl.uniprot.org/uniprot/E3M6A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_017667 ^@ http://purl.uniprot.org/uniprot/E3LU08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty-acid and retinol-binding protein (FARBP) family.|||Secreted http://togogenome.org/gene/31234:GCK72_023162 ^@ http://purl.uniprot.org/uniprot/E3MKE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/31234:GCK72_018235 ^@ http://purl.uniprot.org/uniprot/E3LKS0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_005677 ^@ http://purl.uniprot.org/uniprot/E3LG83 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/31234:GCK72_023400 ^@ http://purl.uniprot.org/uniprot/E3MAK2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/31234:GCK72_018731 ^@ http://purl.uniprot.org/uniprot/E3M0N8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.|||nucleolus http://togogenome.org/gene/31234:GCK72_024327 ^@ http://purl.uniprot.org/uniprot/E3LEA5 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_013298 ^@ http://purl.uniprot.org/uniprot/E3MRH8 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_009596 ^@ http://purl.uniprot.org/uniprot/E3LRY8 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. METTL16/RlmF family. http://togogenome.org/gene/31234:GCK72_017558 ^@ http://purl.uniprot.org/uniprot/E3LTP2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/31234:GCK72_022476 ^@ http://purl.uniprot.org/uniprot/E3N4H3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_023605 ^@ http://purl.uniprot.org/uniprot/E3M204 ^@ Similarity ^@ Belongs to the liprin family. Liprin-alpha subfamily. http://togogenome.org/gene/31234:GCK72_023479 ^@ http://purl.uniprot.org/uniprot/E3MMF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the organo anion transporter (TC 2.A.60) family.|||Cell membrane http://togogenome.org/gene/31234:GCK72_006399 ^@ http://purl.uniprot.org/uniprot/E3LQN4 ^@ Caution|||Similarity ^@ Belongs to the RAB6IP1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_006170 ^@ http://purl.uniprot.org/uniprot/E3LRD0 ^@ Similarity ^@ Belongs to the TMEM9 family. http://togogenome.org/gene/31234:GCK72_004961 ^@ http://purl.uniprot.org/uniprot/E3LGH3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RNase HII family. Eukaryotic subfamily.|||Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/31234:GCK72_021910 ^@ http://purl.uniprot.org/uniprot/E3MF31 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_024828 ^@ http://purl.uniprot.org/uniprot/E3LCK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_018874 ^@ http://purl.uniprot.org/uniprot/E3LZW2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_001214 ^@ http://purl.uniprot.org/uniprot/E3LXN7 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/31234:GCK72_003055 ^@ http://purl.uniprot.org/uniprot/E3MZZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/31234:GCK72_023743 ^@ http://purl.uniprot.org/uniprot/E3M2S7 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/31234:GCK72_000314 ^@ http://purl.uniprot.org/uniprot/E3MX74 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_021974 ^@ http://purl.uniprot.org/uniprot/E3MEX4 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/31234:GCK72_014330 ^@ http://purl.uniprot.org/uniprot/E3MM89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the clarin family.|||Membrane http://togogenome.org/gene/31234:GCK72_017748 ^@ http://purl.uniprot.org/uniprot/E3LU98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_000183 ^@ http://purl.uniprot.org/uniprot/E3NKQ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NTAQ1 family.|||Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.|||Monomer. http://togogenome.org/gene/31234:GCK72_001194 ^@ http://purl.uniprot.org/uniprot/E3LXR0 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/31234:GCK72_011788 ^@ http://purl.uniprot.org/uniprot/E3MSM3 ^@ Subunit ^@ Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin. http://togogenome.org/gene/31234:GCK72_005094 ^@ http://purl.uniprot.org/uniprot/E3LGU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cystinosin family.|||Membrane http://togogenome.org/gene/31234:GCK72_017679 ^@ http://purl.uniprot.org/uniprot/E3LU19 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/31234:GCK72_017470 ^@ http://purl.uniprot.org/uniprot/E3MND0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_002757 ^@ http://purl.uniprot.org/uniprot/E3NKD6 ^@ Similarity ^@ Belongs to the FAM76 family. http://togogenome.org/gene/31234:GCK72_016642 ^@ http://purl.uniprot.org/uniprot/E3NGR1 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_009728 ^@ http://purl.uniprot.org/uniprot/E3LT65 ^@ Similarity ^@ Belongs to the SIKE family. http://togogenome.org/gene/31234:GCK72_024060 ^@ http://purl.uniprot.org/uniprot/E3LCH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/31234:GCK72_002896 ^@ http://purl.uniprot.org/uniprot/E3MXM2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the INP1 family.|||Membrane|||Peroxisome membrane|||Required for peroxisome inheritance. http://togogenome.org/gene/31234:GCK72_006341 ^@ http://purl.uniprot.org/uniprot/E3LQV3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FIS1 family.|||Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.|||Membrane|||Mitochondrion outer membrane|||The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission. http://togogenome.org/gene/31234:GCK72_006105 ^@ http://purl.uniprot.org/uniprot/E3M4U7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_003452 ^@ http://purl.uniprot.org/uniprot/E3NST6 ^@ Function|||Similarity ^@ Belongs to the PET191 family.|||Involved in an early step of the mitochondrial complex IV assembly process. http://togogenome.org/gene/31234:GCK72_007613 ^@ http://purl.uniprot.org/uniprot/E3M977 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/31234:GCK72_004817 ^@ http://purl.uniprot.org/uniprot/E3MZT7 ^@ Similarity ^@ Belongs to the thymidylate kinase family. http://togogenome.org/gene/31234:GCK72_025723 ^@ http://purl.uniprot.org/uniprot/E3MDY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_021983 ^@ http://purl.uniprot.org/uniprot/E3MEW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Membrane http://togogenome.org/gene/31234:GCK72_022958 ^@ http://purl.uniprot.org/uniprot/E3N8E4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/31234:GCK72_010818 ^@ http://purl.uniprot.org/uniprot/E3LWM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein srb family.|||Membrane http://togogenome.org/gene/31234:GCK72_017512 ^@ http://purl.uniprot.org/uniprot/E3LTJ9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_017794 ^@ http://purl.uniprot.org/uniprot/E3LUE4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GcvT family.|||Mitochondrion|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/31234:GCK72_008307 ^@ http://purl.uniprot.org/uniprot/E3MFX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 6A family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_006161 ^@ http://purl.uniprot.org/uniprot/E3LRD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_005969 ^@ http://purl.uniprot.org/uniprot/E3M4G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein srb family.|||Membrane http://togogenome.org/gene/31234:GCK72_009373 ^@ http://purl.uniprot.org/uniprot/E3LSL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_002630 ^@ http://purl.uniprot.org/uniprot/E3LVB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_006690 ^@ http://purl.uniprot.org/uniprot/E3M155 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_023267 ^@ http://purl.uniprot.org/uniprot/E3MAT8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/31234:GCK72_002185 ^@ http://purl.uniprot.org/uniprot/E3MG95 ^@ Similarity ^@ Belongs to the PICALM/SNAP91 family. http://togogenome.org/gene/31234:GCK72_017234 ^@ http://purl.uniprot.org/uniprot/E3N1V2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_010004 ^@ http://purl.uniprot.org/uniprot/E3MCP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_013793 ^@ http://purl.uniprot.org/uniprot/E3N3T3 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_010835 ^@ http://purl.uniprot.org/uniprot/E3LWK2 ^@ Function ^@ E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. http://togogenome.org/gene/31234:GCK72_002128 ^@ http://purl.uniprot.org/uniprot/E3LM10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC7 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/31234:GCK72_011962 ^@ http://purl.uniprot.org/uniprot/E3MK97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP12 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_009515 ^@ http://purl.uniprot.org/uniprot/E3LS73 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex (By similarity). The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H (By similarity). The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits vah-19/Ac45 and vah-20/PRR.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.|||Vacuole membrane http://togogenome.org/gene/31234:GCK72_018147 ^@ http://purl.uniprot.org/uniprot/E3LPV7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_021640 ^@ http://purl.uniprot.org/uniprot/E3N0F8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_023673 ^@ http://purl.uniprot.org/uniprot/E3M2F1 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane|||The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.|||Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.|||extracellular space|||nucleoplasm|||sarcolemma http://togogenome.org/gene/31234:GCK72_022776 ^@ http://purl.uniprot.org/uniprot/E3NLJ3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.|||Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.|||In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.|||Nucleus http://togogenome.org/gene/31234:GCK72_000511 ^@ http://purl.uniprot.org/uniprot/E3M3N1 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/31234:GCK72_024707 ^@ http://purl.uniprot.org/uniprot/E3LD53 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. http://togogenome.org/gene/31234:GCK72_018228 ^@ http://purl.uniprot.org/uniprot/E3LQ29 ^@ Similarity ^@ Belongs to the GPATCH11 family. http://togogenome.org/gene/31234:GCK72_005901 ^@ http://purl.uniprot.org/uniprot/E3M494 ^@ Similarity ^@ Belongs to the SGT family. http://togogenome.org/gene/31234:GCK72_006310 ^@ http://purl.uniprot.org/uniprot/E3LQY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_006088 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_008938 ^@ http://purl.uniprot.org/uniprot/E3MWJ1 ^@ Similarity ^@ Belongs to the SAP18 family. http://togogenome.org/gene/31234:GCK72_015917 ^@ http://purl.uniprot.org/uniprot/E3NNA3 ^@ Similarity ^@ Belongs to the vacuolar ATPase subunit S1 family. http://togogenome.org/gene/31234:GCK72_002332 ^@ http://purl.uniprot.org/uniprot/E3MG77 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_006237 ^@ http://purl.uniprot.org/uniprot/E3LR68 ^@ Similarity ^@ Belongs to the 3-beta-HSD family. http://togogenome.org/gene/31234:GCK72_005564 ^@ http://purl.uniprot.org/uniprot/E3LFW0 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/31234:GCK72_000032 ^@ http://purl.uniprot.org/uniprot/E3MT59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VTA1 family.|||Cytoplasm|||Endosome membrane|||Membrane http://togogenome.org/gene/31234:GCK72_002011 ^@ http://purl.uniprot.org/uniprot/E3LMD4 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_009275 ^@ http://purl.uniprot.org/uniprot/E3N096 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/31234:GCK72_010651 ^@ http://purl.uniprot.org/uniprot/E3LYS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CMC family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_010048 ^@ http://purl.uniprot.org/uniprot/E3MCU2 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/31234:GCK72_006533 ^@ http://purl.uniprot.org/uniprot/E3LQ89 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_010110 ^@ http://purl.uniprot.org/uniprot/E3MD08 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/31234:GCK72_009180 ^@ http://purl.uniprot.org/uniprot/E3ML06 ^@ Similarity ^@ Belongs to the CND2 H2 (condensin-2 subunit 2) family. http://togogenome.org/gene/31234:GCK72_008885 ^@ http://purl.uniprot.org/uniprot/E3M8B2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SH3BP5 family.|||Binds preferentially to the GDP-bound form of rab-11.1.|||Cytoplasmic granule|||Golgi apparatus membrane|||Guanine nucleotide exchange factor for Rab GTPase Rab-11.1. http://togogenome.org/gene/31234:GCK72_017183 ^@ http://purl.uniprot.org/uniprot/E3N548 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/31234:GCK72_013471 ^@ http://purl.uniprot.org/uniprot/E3MRB1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_005655 ^@ http://purl.uniprot.org/uniprot/E3LG60 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/31234:GCK72_013651 ^@ http://purl.uniprot.org/uniprot/E3MSC4 ^@ Function|||Similarity ^@ Belongs to the QNG1 protein family.|||Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly. http://togogenome.org/gene/31234:GCK72_024480 ^@ http://purl.uniprot.org/uniprot/E3LDU1 ^@ Caution|||Function|||Similarity ^@ Belongs to the acetyltransferase ATAT1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically acetylates 'Lys-40' in alpha-tubulin/mec-12 on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for the maintenance of touch receptor neurons and possibly other type of neurons involved in locomotion. http://togogenome.org/gene/31234:GCK72_002240 ^@ http://purl.uniprot.org/uniprot/E3MGF2 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_017716 ^@ http://purl.uniprot.org/uniprot/E3LU55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/31234:GCK72_025001 ^@ http://purl.uniprot.org/uniprot/E3MRQ1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.|||Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_018773 ^@ http://purl.uniprot.org/uniprot/E3LZK6 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/31234:GCK72_004710 ^@ http://purl.uniprot.org/uniprot/E3MHY3 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/31234:GCK72_000572 ^@ http://purl.uniprot.org/uniprot/E3M3U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_012055 ^@ http://purl.uniprot.org/uniprot/E3MK06 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/31234:GCK72_000387 ^@ http://purl.uniprot.org/uniprot/E3N7P9 ^@ Similarity ^@ Belongs to the nudE family. http://togogenome.org/gene/31234:GCK72_018227 ^@ http://purl.uniprot.org/uniprot/E3LQ28 ^@ Similarity ^@ Belongs to the SMC family. RAD50 subfamily. http://togogenome.org/gene/31234:GCK72_007067 ^@ http://purl.uniprot.org/uniprot/E3MV92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_016111 ^@ http://purl.uniprot.org/uniprot/E3N9V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.|||Membrane http://togogenome.org/gene/31234:GCK72_020755 ^@ http://purl.uniprot.org/uniprot/E3MB61 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_010135 ^@ http://purl.uniprot.org/uniprot/E3MD31 ^@ Function|||Similarity ^@ Belongs to the GST superfamily. Omega family.|||Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA). http://togogenome.org/gene/31234:GCK72_025086 ^@ http://purl.uniprot.org/uniprot/E3NAR4 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/31234:GCK72_017358 ^@ http://purl.uniprot.org/uniprot/E3NCI2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).|||Cytoplasm|||Nucleus http://togogenome.org/gene/31234:GCK72_013450 ^@ http://purl.uniprot.org/uniprot/E3ND82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/31234:GCK72_005744 ^@ http://purl.uniprot.org/uniprot/E3MMY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 5'-3' exonuclease family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_009383 ^@ http://purl.uniprot.org/uniprot/E3LSK7 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/31234:GCK72_001062 ^@ http://purl.uniprot.org/uniprot/E3LY39 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/31234:GCK72_013798 ^@ http://purl.uniprot.org/uniprot/E3NRT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.|||Cytoplasm|||Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity. http://togogenome.org/gene/31234:GCK72_001985 ^@ http://purl.uniprot.org/uniprot/E3LMG7 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/31234:GCK72_015530 ^@ http://purl.uniprot.org/uniprot/E3NCA7 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_018974 ^@ http://purl.uniprot.org/uniprot/E3M016 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_018734 ^@ http://purl.uniprot.org/uniprot/E3M0P1 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/31234:GCK72_018873 ^@ http://purl.uniprot.org/uniprot/E3LKS0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_001131 ^@ http://purl.uniprot.org/uniprot/E3LXX3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017576 ^@ http://purl.uniprot.org/uniprot/E3LTR1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_018474 ^@ http://purl.uniprot.org/uniprot/E3LP02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIA subunit 1 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_005909 ^@ http://purl.uniprot.org/uniprot/E3M4A1 ^@ Similarity ^@ Belongs to the RNase H family. http://togogenome.org/gene/31234:GCK72_000293 ^@ http://purl.uniprot.org/uniprot/E3NJ17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TTC30/dfy-1/fleer family.|||Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.|||cilium http://togogenome.org/gene/31234:GCK72_024469 ^@ http://purl.uniprot.org/uniprot/E3LDV4 ^@ Similarity ^@ Belongs to the EEIG family. http://togogenome.org/gene/31234:GCK72_001664 ^@ http://purl.uniprot.org/uniprot/E3LLS1 ^@ Similarity ^@ Belongs to the KIN17 family. http://togogenome.org/gene/31234:GCK72_018325 ^@ http://purl.uniprot.org/uniprot/E3LNK2 ^@ Similarity ^@ Belongs to the peptidase C13 family. http://togogenome.org/gene/31234:GCK72_022577 ^@ http://purl.uniprot.org/uniprot/E3NKH1 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_017107 ^@ http://purl.uniprot.org/uniprot/E3ND07 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/31234:GCK72_015848 ^@ http://purl.uniprot.org/uniprot/E3N9R8 ^@ Similarity ^@ Belongs to the OPI10 family. http://togogenome.org/gene/31234:GCK72_016168 ^@ http://purl.uniprot.org/uniprot/E3NBS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/31234:GCK72_000040 ^@ http://purl.uniprot.org/uniprot/E3MT52 ^@ Similarity ^@ Belongs to the acetyltransferase family. GNA1 subfamily. http://togogenome.org/gene/31234:GCK72_011869 ^@ http://purl.uniprot.org/uniprot/E3ML81 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/31234:GCK72_017937 ^@ http://purl.uniprot.org/uniprot/E3LUU2 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/31234:GCK72_010566 ^@ http://purl.uniprot.org/uniprot/E3LZ13 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/31234:GCK72_021536 ^@ http://purl.uniprot.org/uniprot/E3MH77 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_014074 ^@ http://purl.uniprot.org/uniprot/E3M7R7 ^@ Function|||Subcellular Location Annotation ^@ Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).|||Membrane|||Mitochondrion inner membrane|||Nucleus http://togogenome.org/gene/31234:GCK72_013856 ^@ http://purl.uniprot.org/uniprot/E3M746 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_014121 ^@ http://purl.uniprot.org/uniprot/E3M7W1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallophosphoesterase superfamily. MPPE1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_023495 ^@ http://purl.uniprot.org/uniprot/E3MMD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/31234:GCK72_003682 ^@ http://purl.uniprot.org/uniprot/E3NB31 ^@ Similarity ^@ Belongs to the RRM elav family. http://togogenome.org/gene/31234:GCK72_013918 ^@ http://purl.uniprot.org/uniprot/E3NT06 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_002554 ^@ http://purl.uniprot.org/uniprot/E3LVJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Cytoplasm|||Non-catalytic component of the proteasome.|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/31234:GCK72_020769 ^@ http://purl.uniprot.org/uniprot/E3MBV8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10A family.|||Binds 2 Zn(2+) ions per subunit.|||Can bind about 5 Ca(2+) ions per subunit. http://togogenome.org/gene/31234:GCK72_012721 ^@ http://purl.uniprot.org/uniprot/E3N2F0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017890 ^@ http://purl.uniprot.org/uniprot/E3LUP1 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/31234:GCK72_014138 ^@ http://purl.uniprot.org/uniprot/E3M7Y2 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/31234:GCK72_016481 ^@ http://purl.uniprot.org/uniprot/E3NJE2 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_008314 ^@ http://purl.uniprot.org/uniprot/E3MFW9 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. http://togogenome.org/gene/31234:GCK72_024534 ^@ http://purl.uniprot.org/uniprot/E3LDN4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_003559 ^@ http://purl.uniprot.org/uniprot/E3M8W8 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/31234:GCK72_023362 ^@ http://purl.uniprot.org/uniprot/E3MB31 ^@ Similarity ^@ Belongs to the cuticular collagen family. http://togogenome.org/gene/31234:GCK72_022111 ^@ http://purl.uniprot.org/uniprot/E3MAG7 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_014067 ^@ http://purl.uniprot.org/uniprot/E3M7Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_020177 ^@ http://purl.uniprot.org/uniprot/E3LHW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_023466 ^@ http://purl.uniprot.org/uniprot/E3MMG4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010272 ^@ http://purl.uniprot.org/uniprot/E3MIH0 ^@ Subunit ^@ Heterodimer of 2 subunits, IMMPL1 and IMMPL2. http://togogenome.org/gene/31234:GCK72_020722 ^@ http://purl.uniprot.org/uniprot/E3N179 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_023975 ^@ http://purl.uniprot.org/uniprot/E3LD04 ^@ Function|||Similarity ^@ Belongs to the V-ATPase H subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Subunit H is essential for V-ATPase activity, but not for the assembly of the complex. http://togogenome.org/gene/31234:GCK72_017178 ^@ http://purl.uniprot.org/uniprot/E3N551 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/31234:GCK72_004477 ^@ http://purl.uniprot.org/uniprot/E3MRY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_022945 ^@ http://purl.uniprot.org/uniprot/E3MLU6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_013533 ^@ http://purl.uniprot.org/uniprot/E3MR42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_001522 ^@ http://purl.uniprot.org/uniprot/E3N1L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Membrane http://togogenome.org/gene/31234:GCK72_023183 ^@ http://purl.uniprot.org/uniprot/E3MKR5 ^@ Function|||Similarity ^@ Belongs to the alpha-carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/31234:GCK72_001092 ^@ http://purl.uniprot.org/uniprot/E3LY11 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_024533 ^@ http://purl.uniprot.org/uniprot/E3LDN5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017617 ^@ http://purl.uniprot.org/uniprot/E3LTV3 ^@ Similarity ^@ Belongs to the oligoribonuclease family. http://togogenome.org/gene/31234:GCK72_017666 ^@ http://purl.uniprot.org/uniprot/E3LU07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty-acid and retinol-binding protein (FARBP) family.|||Secreted http://togogenome.org/gene/31234:GCK72_025652 ^@ http://purl.uniprot.org/uniprot/E3MC43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/31234:GCK72_023051 ^@ http://purl.uniprot.org/uniprot/E3N6U1 ^@ Caution|||Similarity ^@ Belongs to the nematode receptor-like protein srg family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_009748 ^@ http://purl.uniprot.org/uniprot/E3LT45 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/31234:GCK72_000287 ^@ http://purl.uniprot.org/uniprot/E3NJ10 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/31234:GCK72_019018 ^@ http://purl.uniprot.org/uniprot/E3LK47 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_013955 ^@ http://purl.uniprot.org/uniprot/E3M7D7 ^@ Similarity ^@ Belongs to the eukaryotic mitochondrial porin family. http://togogenome.org/gene/31234:GCK72_009830 ^@ http://purl.uniprot.org/uniprot/E3LSX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CWC16 family. YJU2 subfamily.|||Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.|||Nucleus|||Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. http://togogenome.org/gene/31234:GCK72_000047 ^@ http://purl.uniprot.org/uniprot/E3MT46 ^@ Similarity ^@ Belongs to the insulin family. http://togogenome.org/gene/31234:GCK72_018480 ^@ http://purl.uniprot.org/uniprot/E3LP08 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/31234:GCK72_013797 ^@ http://purl.uniprot.org/uniprot/E3NE83 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/31234:GCK72_017363 ^@ http://purl.uniprot.org/uniprot/E3NCI9 ^@ Similarity ^@ Belongs to the peptidase C65 family. http://togogenome.org/gene/31234:GCK72_014170 ^@ http://purl.uniprot.org/uniprot/E3M813 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_011868 ^@ http://purl.uniprot.org/uniprot/E3ML80 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/31234:GCK72_002252 ^@ http://purl.uniprot.org/uniprot/E3MGG7 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Monomer. http://togogenome.org/gene/31234:GCK72_020392 ^@ http://purl.uniprot.org/uniprot/E3LIM7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_017731 ^@ http://purl.uniprot.org/uniprot/E3LU78 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_011871 ^@ http://purl.uniprot.org/uniprot/E3ML83 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Component of the 40S small ribosomal subunit. http://togogenome.org/gene/31234:GCK72_013886 ^@ http://purl.uniprot.org/uniprot/E3M769 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.|||Membrane http://togogenome.org/gene/31234:GCK72_009742 ^@ http://purl.uniprot.org/uniprot/E3LT51 ^@ Caution|||Cofactor|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/31234:GCK72_014844 ^@ http://purl.uniprot.org/uniprot/E3M529 ^@ Similarity ^@ Belongs to the SEC10 family. http://togogenome.org/gene/31234:GCK72_000611 ^@ http://purl.uniprot.org/uniprot/E3M3Z3 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/31234:GCK72_006437 ^@ http://purl.uniprot.org/uniprot/E3LQJ5 ^@ Similarity ^@ Belongs to the PDE6D/unc-119 family. http://togogenome.org/gene/31234:GCK72_023663 ^@ http://purl.uniprot.org/uniprot/E3M2E1 ^@ Similarity ^@ Belongs to the PAL/histidase family. http://togogenome.org/gene/31234:GCK72_024362 ^@ http://purl.uniprot.org/uniprot/E3LE70 ^@ Similarity|||Subunit ^@ Belongs to the type II pantothenate kinase family.|||Homodimer. Interacts with PKM.|||In the N-terminal section; belongs to the type II pantothenate kinase family. http://togogenome.org/gene/31234:GCK72_008618 ^@ http://purl.uniprot.org/uniprot/E3NC86 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.|||Belongs to the arsA ATPase family.|||Cytoplasm|||Endoplasmic reticulum|||Homodimer. http://togogenome.org/gene/31234:GCK72_011901 ^@ http://purl.uniprot.org/uniprot/E3MLB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Orai family.|||Membrane http://togogenome.org/gene/31234:GCK72_001883 ^@ http://purl.uniprot.org/uniprot/E3LMS4 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/31234:GCK72_019443 ^@ http://purl.uniprot.org/uniprot/E3LKS3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.|||Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.|||Homotetramer. http://togogenome.org/gene/31234:GCK72_010982 ^@ http://purl.uniprot.org/uniprot/E3LX73 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_009687 ^@ http://purl.uniprot.org/uniprot/E3LTB2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_026069 ^@ http://purl.uniprot.org/uniprot/E3MPB2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_019513 ^@ http://purl.uniprot.org/uniprot/E3LL52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty-acid and retinol-binding protein (FARBP) family.|||Secreted http://togogenome.org/gene/31234:GCK72_020191 ^@ http://purl.uniprot.org/uniprot/E3LHX9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_005665 ^@ http://purl.uniprot.org/uniprot/E3LG69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.|||Belongs to the GAMAD family.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_003540 ^@ http://purl.uniprot.org/uniprot/E3M8U8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_004797 ^@ http://purl.uniprot.org/uniprot/E3MZV5 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_022093 ^@ http://purl.uniprot.org/uniprot/E3MAI8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_018346 ^@ http://purl.uniprot.org/uniprot/E3LNL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_002436 ^@ http://purl.uniprot.org/uniprot/E3LVW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallophosphoesterase superfamily. MPPE1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_016988 ^@ http://purl.uniprot.org/uniprot/E3MHE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lin-54 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_024728 ^@ http://purl.uniprot.org/uniprot/E3LD33 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/31234:GCK72_022042 ^@ http://purl.uniprot.org/uniprot/E3NB67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_003684 ^@ http://purl.uniprot.org/uniprot/E3NB29 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_024287 ^@ http://purl.uniprot.org/uniprot/E3LEE7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lunapark family.|||Endoplasmic reticulum membrane|||Plays a role in determining ER morphology.|||The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation. http://togogenome.org/gene/31234:GCK72_022896 ^@ http://purl.uniprot.org/uniprot/E3MLN9 ^@ Caution|||Similarity ^@ Belongs to the nematode receptor-like protein srg family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_002242 ^@ http://purl.uniprot.org/uniprot/E3MGF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.|||Membrane http://togogenome.org/gene/31234:GCK72_025536 ^@ http://purl.uniprot.org/uniprot/E3MCF0 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.|||Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. http://togogenome.org/gene/31234:GCK72_023742 ^@ http://purl.uniprot.org/uniprot/E3M2S6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM129 family.|||Membrane http://togogenome.org/gene/31234:GCK72_001034 ^@ http://purl.uniprot.org/uniprot/E3LY64 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_005667 ^@ http://purl.uniprot.org/uniprot/E3LG71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM53 family.|||Membrane|||Nucleus outer membrane http://togogenome.org/gene/31234:GCK72_001320 ^@ http://purl.uniprot.org/uniprot/E3LXB7 ^@ Similarity ^@ Belongs to the WD repeat PWP2 family. http://togogenome.org/gene/31234:GCK72_018410 ^@ http://purl.uniprot.org/uniprot/E3LNT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_009984 ^@ http://purl.uniprot.org/uniprot/E3MCM1 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/31234:GCK72_025550 ^@ http://purl.uniprot.org/uniprot/E3MCE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/31234:GCK72_006411 ^@ http://purl.uniprot.org/uniprot/E3LQM0 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/31234:GCK72_018201 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_013950 ^@ http://purl.uniprot.org/uniprot/E3M796 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_009523 ^@ http://purl.uniprot.org/uniprot/E3LS62 ^@ Similarity ^@ Belongs to the calreticulin family. http://togogenome.org/gene/31234:GCK72_011970 ^@ http://purl.uniprot.org/uniprot/E3MK88 ^@ Similarity ^@ Belongs to the COG2 family. http://togogenome.org/gene/31234:GCK72_016568 ^@ http://purl.uniprot.org/uniprot/E3MTV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecE/SEC61-gamma family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/31234:GCK72_023280 ^@ http://purl.uniprot.org/uniprot/E3MAV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_005925 ^@ http://purl.uniprot.org/uniprot/A8VT33 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_006580 ^@ http://purl.uniprot.org/uniprot/E3LRP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/31234:GCK72_006081 ^@ http://purl.uniprot.org/uniprot/E3M4S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS5 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/31234:GCK72_023706 ^@ http://purl.uniprot.org/uniprot/E3M2N1 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/31234:GCK72_018671 ^@ http://purl.uniprot.org/uniprot/E3M0H2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_005842 ^@ http://purl.uniprot.org/uniprot/E3M431 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CCDC25 family.|||Endomembrane system|||Interacts (via cytoplasmic region) with ILK. http://togogenome.org/gene/31234:GCK72_002383 ^@ http://purl.uniprot.org/uniprot/E3LW17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I NDUFB10 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_014654 ^@ http://purl.uniprot.org/uniprot/E3M6Y8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_013454 ^@ http://purl.uniprot.org/uniprot/E3NSC1 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. http://togogenome.org/gene/31234:GCK72_010018 ^@ http://purl.uniprot.org/uniprot/E3MCR2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_017430 ^@ http://purl.uniprot.org/uniprot/E3MN86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM144 family.|||Membrane http://togogenome.org/gene/31234:GCK72_005923 ^@ http://purl.uniprot.org/uniprot/E3M4B5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 4 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_019645 ^@ http://purl.uniprot.org/uniprot/E3LJS9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_019903 ^@ http://purl.uniprot.org/uniprot/E3LJF9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_006433 ^@ http://purl.uniprot.org/uniprot/E3LQK0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_014794 ^@ http://purl.uniprot.org/uniprot/E3M6J8 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/31234:GCK72_022586 ^@ http://purl.uniprot.org/uniprot/E3N7Z0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_004422 ^@ http://purl.uniprot.org/uniprot/E3N1A4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_018004 ^@ http://purl.uniprot.org/uniprot/E3LPF8 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_007240 ^@ http://purl.uniprot.org/uniprot/E3MJ59 ^@ Similarity ^@ Belongs to the TAF11 family. http://togogenome.org/gene/31234:GCK72_023733 ^@ http://purl.uniprot.org/uniprot/E3M2R8 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/31234:GCK72_020332 ^@ http://purl.uniprot.org/uniprot/E3LIF7 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/31234:GCK72_019971 ^@ http://purl.uniprot.org/uniprot/E3LHA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/31234:GCK72_006742 ^@ http://purl.uniprot.org/uniprot/E3M0X6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_010757 ^@ http://purl.uniprot.org/uniprot/E3LKF8 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_010646 ^@ http://purl.uniprot.org/uniprot/E3LYT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone deacetylase family. HD Type 1 subfamily.|||Nucleus http://togogenome.org/gene/31234:GCK72_009505 ^@ http://purl.uniprot.org/uniprot/E3LS83 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/31234:GCK72_024873 ^@ http://purl.uniprot.org/uniprot/E3LCA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NIP3 family.|||Membrane http://togogenome.org/gene/31234:GCK72_003371 ^@ http://purl.uniprot.org/uniprot/E3NHK4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_006159 ^@ http://purl.uniprot.org/uniprot/E3LRE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_005472 ^@ http://purl.uniprot.org/uniprot/E3LFK7 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_003193 ^@ http://purl.uniprot.org/uniprot/E3NJ32 ^@ Similarity ^@ Belongs to the RdRP family. http://togogenome.org/gene/31234:GCK72_019739 ^@ http://purl.uniprot.org/uniprot/E3MZ51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_024325 ^@ http://purl.uniprot.org/uniprot/E3LEA7 ^@ Similarity ^@ Belongs to the vasopressin/oxytocin family. http://togogenome.org/gene/31234:GCK72_002730 ^@ http://purl.uniprot.org/uniprot/E3LUZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_004084 ^@ http://purl.uniprot.org/uniprot/E3MZR0 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_019975 ^@ http://purl.uniprot.org/uniprot/E3LHA4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_019340 ^@ http://purl.uniprot.org/uniprot/E3LK25 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_025914 ^@ http://purl.uniprot.org/uniprot/E3MUZ1 ^@ Subcellular Location Annotation ^@ cytosol http://togogenome.org/gene/31234:GCK72_010828 ^@ http://purl.uniprot.org/uniprot/E3LWL1 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_019308 ^@ http://purl.uniprot.org/uniprot/E3LJX9 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_002193 ^@ http://purl.uniprot.org/uniprot/E3MGA1 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/31234:GCK72_009246 ^@ http://purl.uniprot.org/uniprot/E3NFY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty-acid and retinol-binding protein (FARBP) family.|||Secreted http://togogenome.org/gene/31234:GCK72_010993 ^@ http://purl.uniprot.org/uniprot/E3LX61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with an ATP-specific beta subunit, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with a GTP-specific beta subunit forms a GDP-forming succinyl-CoA synthetase (G-SCS).|||Mitochondrion|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. http://togogenome.org/gene/31234:GCK72_005790 ^@ http://purl.uniprot.org/uniprot/E3MMT1 ^@ Similarity ^@ Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily. http://togogenome.org/gene/31234:GCK72_025596 ^@ http://purl.uniprot.org/uniprot/E3MC97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_002385 ^@ http://purl.uniprot.org/uniprot/E3LW15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_008207 ^@ http://purl.uniprot.org/uniprot/E3MNY4 ^@ Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family. http://togogenome.org/gene/31234:GCK72_015004 ^@ http://purl.uniprot.org/uniprot/E3M5L2 ^@ Similarity ^@ Belongs to the PPP phosphatase family. PP-2B subfamily. http://togogenome.org/gene/31234:GCK72_018152 ^@ http://purl.uniprot.org/uniprot/E3LPW1 ^@ Similarity ^@ Belongs to the MIF family. http://togogenome.org/gene/31234:GCK72_017735 ^@ http://purl.uniprot.org/uniprot/E3LU83 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_024171 ^@ http://purl.uniprot.org/uniprot/E3LEQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_012052 ^@ http://purl.uniprot.org/uniprot/E3MK08 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_015388 ^@ http://purl.uniprot.org/uniprot/E3NLY3 ^@ Similarity ^@ Belongs to the ATG101 family. http://togogenome.org/gene/31234:GCK72_014020 ^@ http://purl.uniprot.org/uniprot/E3M7K4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fic family.|||Membrane http://togogenome.org/gene/31234:GCK72_017467 ^@ http://purl.uniprot.org/uniprot/E3MNC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the activator 1 large subunit family.|||Nucleus http://togogenome.org/gene/31234:GCK72_010175 ^@ http://purl.uniprot.org/uniprot/E3MI93 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/31234:GCK72_024803 ^@ http://purl.uniprot.org/uniprot/E3LCN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_010644 ^@ http://purl.uniprot.org/uniprot/E3LYT5 ^@ Similarity ^@ Belongs to the canopy family. http://togogenome.org/gene/31234:GCK72_009614 ^@ http://purl.uniprot.org/uniprot/E3LRW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/31234:GCK72_015971 ^@ http://purl.uniprot.org/uniprot/E3MYK6 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/31234:GCK72_013287 ^@ http://purl.uniprot.org/uniprot/E3MRJ1 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/31234:GCK72_001873 ^@ http://purl.uniprot.org/uniprot/E3LMT6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_009633 ^@ http://purl.uniprot.org/uniprot/E3LRV1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 19 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/31234:GCK72_014628 ^@ http://purl.uniprot.org/uniprot/E3M5Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELL/occludin family.|||Nucleus http://togogenome.org/gene/31234:GCK72_018661 ^@ http://purl.uniprot.org/uniprot/E3M0F5 ^@ Similarity ^@ Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. http://togogenome.org/gene/31234:GCK72_018260 ^@ http://purl.uniprot.org/uniprot/E3LKS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_020182 ^@ http://purl.uniprot.org/uniprot/E3LHX1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_013897 ^@ http://purl.uniprot.org/uniprot/E3M781 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_021557 ^@ http://purl.uniprot.org/uniprot/E3MHA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_013511 ^@ http://purl.uniprot.org/uniprot/E3NPB4 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/31234:GCK72_017999 ^@ http://purl.uniprot.org/uniprot/E3LPE8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_020707 ^@ http://purl.uniprot.org/uniprot/E3N145 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_000866 ^@ http://purl.uniprot.org/uniprot/E3N4R4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL1 family. http://togogenome.org/gene/31234:GCK72_013371 ^@ http://purl.uniprot.org/uniprot/E3N5L6 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_018104 ^@ http://purl.uniprot.org/uniprot/E3LPR3 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/31234:GCK72_018052 ^@ http://purl.uniprot.org/uniprot/E3LPL0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_002076 ^@ http://purl.uniprot.org/uniprot/E3LM65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/31234:GCK72_010595 ^@ http://purl.uniprot.org/uniprot/E3LYY5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS12 family. http://togogenome.org/gene/31234:GCK72_008731 ^@ http://purl.uniprot.org/uniprot/E3M877 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/31234:GCK72_025391 ^@ http://purl.uniprot.org/uniprot/E3MJP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_000171 ^@ http://purl.uniprot.org/uniprot/E3NE25 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_006036 ^@ http://purl.uniprot.org/uniprot/E3M4M9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/31234:GCK72_000704 ^@ http://purl.uniprot.org/uniprot/E3M3A9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010727 ^@ http://purl.uniprot.org/uniprot/E3LWW9 ^@ Similarity ^@ Belongs to the MAK16 family. http://togogenome.org/gene/31234:GCK72_004786 ^@ http://purl.uniprot.org/uniprot/E3MZW4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_009786 ^@ http://purl.uniprot.org/uniprot/E3LT15 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/31234:GCK72_009860 ^@ http://purl.uniprot.org/uniprot/E3LSU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat UTP18 family.|||nucleolus http://togogenome.org/gene/31234:GCK72_021866 ^@ http://purl.uniprot.org/uniprot/E3MF78 ^@ Similarity ^@ Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily. http://togogenome.org/gene/31234:GCK72_006867 ^@ http://purl.uniprot.org/uniprot/E3M1V4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_000551 ^@ http://purl.uniprot.org/uniprot/E3M3S6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_010499 ^@ http://purl.uniprot.org/uniprot/E3LZ91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-50 family.|||Membrane http://togogenome.org/gene/31234:GCK72_024095 ^@ http://purl.uniprot.org/uniprot/E3LCD8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_009525 ^@ http://purl.uniprot.org/uniprot/E3LS60 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/31234:GCK72_000475 ^@ http://purl.uniprot.org/uniprot/E3MX25 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/31234:GCK72_018985 ^@ http://purl.uniprot.org/uniprot/E3M003 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_023220 ^@ http://purl.uniprot.org/uniprot/E3MAP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.|||Membrane http://togogenome.org/gene/31234:GCK72_022335 ^@ http://purl.uniprot.org/uniprot/E3N4C0 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/31234:GCK72_018149 ^@ http://purl.uniprot.org/uniprot/E3LPV9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_009721 ^@ http://purl.uniprot.org/uniprot/E3LT72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein disulfide isomerase family.|||Endoplasmic reticulum lumen http://togogenome.org/gene/31234:GCK72_022011 ^@ http://purl.uniprot.org/uniprot/E3MET7 ^@ Similarity ^@ Belongs to the CDK5RAP3 family. http://togogenome.org/gene/31234:GCK72_003239 ^@ http://purl.uniprot.org/uniprot/E3NJS1 ^@ Similarity ^@ Belongs to the peptidase S8 family. Furin subfamily. http://togogenome.org/gene/31234:GCK72_016295 ^@ http://purl.uniprot.org/uniprot/E3MYC3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_009018 ^@ http://purl.uniprot.org/uniprot/E3MWH0 ^@ Similarity ^@ Belongs to the rogdi family. http://togogenome.org/gene/31234:GCK72_020900 ^@ http://purl.uniprot.org/uniprot/E3MBD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_010245 ^@ http://purl.uniprot.org/uniprot/E3MIE4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_014153 ^@ http://purl.uniprot.org/uniprot/E3NWV3 ^@ Similarity ^@ Belongs to the DNA polymerase delta/II small subunit family. http://togogenome.org/gene/31234:GCK72_003537 ^@ http://purl.uniprot.org/uniprot/E3M8U5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IMPACT family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_005386 ^@ http://purl.uniprot.org/uniprot/E3LFD0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c-type heme lyase family.|||Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/31234:GCK72_000089 ^@ http://purl.uniprot.org/uniprot/E3NHU0 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/31234:GCK72_009706 ^@ http://purl.uniprot.org/uniprot/E3LT95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS31 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_010168 ^@ http://purl.uniprot.org/uniprot/E3MI86 ^@ Similarity ^@ Belongs to the LIMR family. http://togogenome.org/gene/31234:GCK72_022262 ^@ http://purl.uniprot.org/uniprot/E3MA10 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily. http://togogenome.org/gene/31234:GCK72_017905 ^@ http://purl.uniprot.org/uniprot/E3LUQ8 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/31234:GCK72_000170 ^@ http://purl.uniprot.org/uniprot/E3NE24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_000384 ^@ http://purl.uniprot.org/uniprot/E3NLI8 ^@ Similarity ^@ Belongs to the acetyltransferase family. NAA60 subfamily. http://togogenome.org/gene/31234:GCK72_025793 ^@ http://purl.uniprot.org/uniprot/E3ME62 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_018221 ^@ http://purl.uniprot.org/uniprot/E3LQ24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.|||myofibril http://togogenome.org/gene/31234:GCK72_005374 ^@ http://purl.uniprot.org/uniprot/E3LFB9 ^@ Similarity ^@ Belongs to the GTR/RAG GTP-binding protein family. http://togogenome.org/gene/31234:GCK72_005998 ^@ http://purl.uniprot.org/uniprot/E3M4J3 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srg family. http://togogenome.org/gene/31234:GCK72_003676 ^@ http://purl.uniprot.org/uniprot/E3NB38 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/31234:GCK72_013723 ^@ http://purl.uniprot.org/uniprot/E3NSP0 ^@ Similarity ^@ Belongs to the peptidase C78 family. http://togogenome.org/gene/31234:GCK72_005569 ^@ http://purl.uniprot.org/uniprot/E3LFW5 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. LDH family. http://togogenome.org/gene/31234:GCK72_019154 ^@ http://purl.uniprot.org/uniprot/E3LKU5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/31234:GCK72_013682 ^@ http://purl.uniprot.org/uniprot/E3MS88 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_009698 ^@ http://purl.uniprot.org/uniprot/E3LTA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial ribosomal protein bL35 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_016456 ^@ http://purl.uniprot.org/uniprot/E3MQW6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_019938 ^@ http://purl.uniprot.org/uniprot/E3LJK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_010296 ^@ http://purl.uniprot.org/uniprot/E3MI78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEN-2 family.|||Membrane http://togogenome.org/gene/31234:GCK72_020160 ^@ http://purl.uniprot.org/uniprot/E3LHV1 ^@ Similarity ^@ Belongs to the OPA3 family. http://togogenome.org/gene/31234:GCK72_007626 ^@ http://purl.uniprot.org/uniprot/E3M998 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_009853 ^@ http://purl.uniprot.org/uniprot/E3LSU8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the protein prenyltransferase subunit beta family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX. http://togogenome.org/gene/31234:GCK72_025172 ^@ http://purl.uniprot.org/uniprot/E3MZB2 ^@ Similarity ^@ Belongs to the flavin monoamine oxidase family. http://togogenome.org/gene/31234:GCK72_021784 ^@ http://purl.uniprot.org/uniprot/E3N6F3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/31234:GCK72_015034 ^@ http://purl.uniprot.org/uniprot/E3M5P1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/31234:GCK72_016186 ^@ http://purl.uniprot.org/uniprot/E3NBR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_023168 ^@ http://purl.uniprot.org/uniprot/E3MKD4 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/31234:GCK72_009020 ^@ http://purl.uniprot.org/uniprot/E3MWH2 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_022045 ^@ http://purl.uniprot.org/uniprot/E3NB70 ^@ Similarity ^@ Belongs to the phospholipase D family. http://togogenome.org/gene/31234:GCK72_003586 ^@ http://purl.uniprot.org/uniprot/E3M8Z0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_010251 ^@ http://purl.uniprot.org/uniprot/E3MIE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_006234 ^@ http://purl.uniprot.org/uniprot/E3LR71 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/31234:GCK72_004790 ^@ http://purl.uniprot.org/uniprot/E3MZW1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_006600 ^@ http://purl.uniprot.org/uniprot/E3LRM0 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. http://togogenome.org/gene/31234:GCK72_019996 ^@ http://purl.uniprot.org/uniprot/E3LHC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_017531 ^@ http://purl.uniprot.org/uniprot/E3LTL8 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_005704 ^@ http://purl.uniprot.org/uniprot/E3MN26 ^@ Similarity ^@ Belongs to the CDI family. http://togogenome.org/gene/31234:GCK72_001094 ^@ http://purl.uniprot.org/uniprot/E3LY08 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_011885 ^@ http://purl.uniprot.org/uniprot/E3ML97 ^@ Function|||Similarity ^@ Belongs to the protein sulfotransferase family.|||Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate. http://togogenome.org/gene/31234:GCK72_004466 ^@ http://purl.uniprot.org/uniprot/E3MRX6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_015645 ^@ http://purl.uniprot.org/uniprot/E3NLB5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||nucleolus http://togogenome.org/gene/31234:GCK72_011245 ^@ http://purl.uniprot.org/uniprot/E3MW96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/31234:GCK72_001447 ^@ http://purl.uniprot.org/uniprot/E3MFD5 ^@ Similarity ^@ Belongs to the DAMOX/DASOX family. http://togogenome.org/gene/31234:GCK72_023798 ^@ http://purl.uniprot.org/uniprot/E3M225 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_010992 ^@ http://purl.uniprot.org/uniprot/E3LX62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRN7/TAF1B family.|||nucleolus http://togogenome.org/gene/31234:GCK72_013753 ^@ http://purl.uniprot.org/uniprot/E3N3X5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_017600 ^@ http://purl.uniprot.org/uniprot/E3LTT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acid sphingomyelinase family.|||Secreted http://togogenome.org/gene/31234:GCK72_000598 ^@ http://purl.uniprot.org/uniprot/E3M3X6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_025508 ^@ http://purl.uniprot.org/uniprot/E3MJB5 ^@ Function|||Similarity ^@ Belongs to the PKI family.|||Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. http://togogenome.org/gene/31234:GCK72_004441 ^@ http://purl.uniprot.org/uniprot/E3N187 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/31234:GCK72_000392 ^@ http://purl.uniprot.org/uniprot/E3N7Q2 ^@ Similarity ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. http://togogenome.org/gene/31234:GCK72_010156 ^@ http://purl.uniprot.org/uniprot/E3MI21 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding elongation factor family. LepA subfamily.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Mitochondrion inner membrane|||Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. http://togogenome.org/gene/31234:GCK72_017209 ^@ http://purl.uniprot.org/uniprot/E3NPQ2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/31234:GCK72_023217 ^@ http://purl.uniprot.org/uniprot/E3MAN7 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/31234:GCK72_008233 ^@ http://purl.uniprot.org/uniprot/E3MP14 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/31234:GCK72_000708 ^@ http://purl.uniprot.org/uniprot/E3M3B4 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_023738 ^@ http://purl.uniprot.org/uniprot/E3M2S2 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_019875 ^@ http://purl.uniprot.org/uniprot/E3LJD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_009997 ^@ http://purl.uniprot.org/uniprot/E3MCN5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARPC4 family.|||Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_010718 ^@ http://purl.uniprot.org/uniprot/E3LWX8 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/31234:GCK72_019960 ^@ http://purl.uniprot.org/uniprot/E3LH89 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_024085 ^@ http://purl.uniprot.org/uniprot/E3LCE7 ^@ Similarity ^@ Belongs to the apyrase family. http://togogenome.org/gene/31234:GCK72_008452 ^@ http://purl.uniprot.org/uniprot/E3MY52 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II.|||Cytoplasm|||Nucleus|||Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/31234:GCK72_013679 ^@ http://purl.uniprot.org/uniprot/E3MS91 ^@ Similarity ^@ Belongs to the BLOC1S2 family. http://togogenome.org/gene/31234:GCK72_008531 ^@ http://purl.uniprot.org/uniprot/E3NEF9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.|||Belongs to the MoaD family. MOCS2A subfamily.|||C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.|||Cytoplasm|||Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits. http://togogenome.org/gene/31234:GCK72_005947 ^@ http://purl.uniprot.org/uniprot/E3M4D9 ^@ Similarity ^@ Belongs to the DSH family. http://togogenome.org/gene/31234:GCK72_004799 ^@ http://purl.uniprot.org/uniprot/E3MZV3 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/31234:GCK72_025781 ^@ http://purl.uniprot.org/uniprot/E3ME49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_006751 ^@ http://purl.uniprot.org/uniprot/E3M0W8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/31234:GCK72_002406 ^@ http://purl.uniprot.org/uniprot/E3LVZ3 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum|||Golgi apparatus http://togogenome.org/gene/31234:GCK72_000587 ^@ http://purl.uniprot.org/uniprot/E3M367 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/31234:GCK72_024560 ^@ http://purl.uniprot.org/uniprot/E3LDK8 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_014197 ^@ http://purl.uniprot.org/uniprot/E3MST0 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/31234:GCK72_015281 ^@ http://purl.uniprot.org/uniprot/E3NIG8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/31234:GCK72_019606 ^@ http://purl.uniprot.org/uniprot/E3LJP2 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_008383 ^@ http://purl.uniprot.org/uniprot/E3NF04 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/31234:GCK72_009295 ^@ http://purl.uniprot.org/uniprot/E3N083 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RPAP2 family.|||Nucleus|||Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation. http://togogenome.org/gene/31234:GCK72_010186 ^@ http://purl.uniprot.org/uniprot/E3MI29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.|||Mitochondrion|||Nucleus http://togogenome.org/gene/31234:GCK72_005271 ^@ http://purl.uniprot.org/uniprot/E3LF16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad17/RAD24 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_001270 ^@ http://purl.uniprot.org/uniprot/E3LXH1 ^@ Similarity ^@ Belongs to the TCF25 family. http://togogenome.org/gene/31234:GCK72_001783 ^@ http://purl.uniprot.org/uniprot/E3LLQ2 ^@ Similarity ^@ Belongs to the YOS1 family. http://togogenome.org/gene/31234:GCK72_019392 ^@ http://purl.uniprot.org/uniprot/E3LKE4 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_004785 ^@ http://purl.uniprot.org/uniprot/E3MZW5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/31234:GCK72_025344 ^@ http://purl.uniprot.org/uniprot/E3MJT7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FIS1 family.|||Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.|||Membrane|||Mitochondrion outer membrane|||The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission. http://togogenome.org/gene/31234:GCK72_009016 ^@ http://purl.uniprot.org/uniprot/E3MWG9 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. http://togogenome.org/gene/31234:GCK72_023244 ^@ http://purl.uniprot.org/uniprot/E3MAR3 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_010283 ^@ http://purl.uniprot.org/uniprot/E3MI66 ^@ Similarity ^@ Belongs to the OSBP family. http://togogenome.org/gene/31234:GCK72_024520 ^@ http://purl.uniprot.org/uniprot/E3LDQ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/31234:GCK72_003819 ^@ http://purl.uniprot.org/uniprot/E3MXG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode transthyretin-like family.|||Secreted http://togogenome.org/gene/31234:GCK72_014269 ^@ http://purl.uniprot.org/uniprot/E3MT00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_002224 ^@ http://purl.uniprot.org/uniprot/E3MGD6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/31234:GCK72_000869 ^@ http://purl.uniprot.org/uniprot/E3N4R7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.|||cytoskeleton http://togogenome.org/gene/31234:GCK72_002442 ^@ http://purl.uniprot.org/uniprot/E3LVW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRM6/GCD10 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_008532 ^@ http://purl.uniprot.org/uniprot/E3NEF8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NADPH--cytochrome P450 reductase family.|||Binds 1 FAD per monomer.|||Binds 1 FMN per monomer.|||Endoplasmic reticulum membrane|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||In the N-terminal section; belongs to the flavodoxin family.|||This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. http://togogenome.org/gene/31234:GCK72_016091 ^@ http://purl.uniprot.org/uniprot/E3NLA1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_019194 ^@ http://purl.uniprot.org/uniprot/E3LL78 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srg family. http://togogenome.org/gene/31234:GCK72_016454 ^@ http://purl.uniprot.org/uniprot/E3MQW4 ^@ Similarity ^@ Belongs to the glutaminyl-peptide cyclotransferase family. http://togogenome.org/gene/31234:GCK72_016209 ^@ http://purl.uniprot.org/uniprot/E3NHX8 ^@ Similarity ^@ Belongs to the HSBP1 family. http://togogenome.org/gene/31234:GCK72_019542 ^@ http://purl.uniprot.org/uniprot/E3LLA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_018425 ^@ http://purl.uniprot.org/uniprot/E3LNV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_006713 ^@ http://purl.uniprot.org/uniprot/E3M109 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein sre family.|||Membrane http://togogenome.org/gene/31234:GCK72_008129 ^@ http://purl.uniprot.org/uniprot/E3MDH3 ^@ Similarity ^@ Belongs to the NPL4 family. http://togogenome.org/gene/31234:GCK72_013525 ^@ http://purl.uniprot.org/uniprot/E3MR50 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_014517 ^@ http://purl.uniprot.org/uniprot/E3M6B2 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL11 family.|||Binds directly to 26S ribosomal RNA. http://togogenome.org/gene/31234:GCK72_010760 ^@ http://purl.uniprot.org/uniprot/E3LWT6 ^@ Function|||Subcellular Location Annotation ^@ Endosome|||Late endosome|||Membrane|||Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. http://togogenome.org/gene/31234:GCK72_014873 ^@ http://purl.uniprot.org/uniprot/E3M561 ^@ Similarity ^@ Belongs to the SLT11 family. http://togogenome.org/gene/31234:GCK72_011630 ^@ http://purl.uniprot.org/uniprot/E3MNK3 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/31234:GCK72_011494 ^@ http://purl.uniprot.org/uniprot/E3MII4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Mitochondrion|||Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits. http://togogenome.org/gene/31234:GCK72_013064 ^@ http://purl.uniprot.org/uniprot/E3M1V1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_017800 ^@ http://purl.uniprot.org/uniprot/E3LUF0 ^@ Cofactor ^@ Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/31234:GCK72_016041 ^@ http://purl.uniprot.org/uniprot/E3NDD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS33 family.|||Mitochondrion http://togogenome.org/gene/31234:GCK72_009612 ^@ http://purl.uniprot.org/uniprot/E3LRX0 ^@ Similarity ^@ Belongs to the pym family. http://togogenome.org/gene/31234:GCK72_018673 ^@ http://purl.uniprot.org/uniprot/E3M0H4 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/31234:GCK72_005431 ^@ http://purl.uniprot.org/uniprot/E3LFH2 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_005409 ^@ http://purl.uniprot.org/uniprot/E3LFE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Cytoplasm|||LSm subunits form a heteromer with a donut shape.|||P-body|||Probably involved with other LSm subunits in the general process of degradation of mRNAs. http://togogenome.org/gene/31234:GCK72_006563 ^@ http://purl.uniprot.org/uniprot/E3LRQ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.|||Cell membrane|||Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. http://togogenome.org/gene/31234:GCK72_015156 ^@ http://purl.uniprot.org/uniprot/E3N566 ^@ Similarity ^@ Belongs to the ATPase gamma chain family. http://togogenome.org/gene/31234:GCK72_016750 ^@ http://purl.uniprot.org/uniprot/E3MQA9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_017280 ^@ http://purl.uniprot.org/uniprot/E3NMP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_004247 ^@ http://purl.uniprot.org/uniprot/E3MQ20 ^@ Function ^@ Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. http://togogenome.org/gene/31234:GCK72_022268 ^@ http://purl.uniprot.org/uniprot/E3MA01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/31234:GCK72_004976 ^@ http://purl.uniprot.org/uniprot/E3LGI5 ^@ Similarity ^@ Belongs to the TCP11 family. http://togogenome.org/gene/31234:GCK72_014953 ^@ http://purl.uniprot.org/uniprot/E3M5E9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMO family.|||Endoplasmic reticulum membrane|||Membrane|||Microsome membrane http://togogenome.org/gene/31234:GCK72_005604 ^@ http://purl.uniprot.org/uniprot/E3LG05 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RER1 family.|||Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.|||Membrane http://togogenome.org/gene/31234:GCK72_018014 ^@ http://purl.uniprot.org/uniprot/E3LPH2 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/31234:GCK72_019935 ^@ http://purl.uniprot.org/uniprot/E3LJJ7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/31234:GCK72_005032 ^@ http://purl.uniprot.org/uniprot/E3LGN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_001547 ^@ http://purl.uniprot.org/uniprot/E3N1J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/31234:GCK72_000700 ^@ http://purl.uniprot.org/uniprot/E3M3A5 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_000385 ^@ http://purl.uniprot.org/uniprot/E3NKK2 ^@ Similarity ^@ Belongs to the WD repeat TAF5 family. http://togogenome.org/gene/31234:GCK72_009145 ^@ http://purl.uniprot.org/uniprot/E3MKW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_024956 ^@ http://purl.uniprot.org/uniprot/E3MVN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_015941 ^@ http://purl.uniprot.org/uniprot/E3NGV9 ^@ Caution|||Similarity ^@ Belongs to the peptidase C2 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_002267 ^@ http://purl.uniprot.org/uniprot/E3MGI3 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/31234:GCK72_016595 ^@ http://purl.uniprot.org/uniprot/E3MTS3 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/31234:GCK72_010513 ^@ http://purl.uniprot.org/uniprot/E3LZ74 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.|||Belongs to the DNA polymerase alpha subunit B family.|||Nucleus http://togogenome.org/gene/31234:GCK72_003735 ^@ http://purl.uniprot.org/uniprot/E3MXI7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/31234:GCK72_023301 ^@ http://purl.uniprot.org/uniprot/E3MAX4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/31234:GCK72_002400 ^@ http://purl.uniprot.org/uniprot/E3LW00 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/31234:GCK72_004956 ^@ http://purl.uniprot.org/uniprot/E3LGG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF3A3 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_005747 ^@ http://purl.uniprot.org/uniprot/E3MMY4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.|||Nucleus http://togogenome.org/gene/31234:GCK72_005964 ^@ http://purl.uniprot.org/uniprot/E3M4F9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nematode receptor-like protein srb family.|||Membrane http://togogenome.org/gene/31234:GCK72_019215 ^@ http://purl.uniprot.org/uniprot/E3LLC6 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/31234:GCK72_023089 ^@ http://purl.uniprot.org/uniprot/E3MKL4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/31234:GCK72_002156 ^@ http://purl.uniprot.org/uniprot/E3LLY1 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. UBA5 subfamily. http://togogenome.org/gene/31234:GCK72_007821 ^@ http://purl.uniprot.org/uniprot/E3NFL4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_019339 ^@ http://purl.uniprot.org/uniprot/E3LK24 ^@ Similarity ^@ Belongs to the nematode receptor-like protein srd family. http://togogenome.org/gene/31234:GCK72_020316 ^@ http://purl.uniprot.org/uniprot/E3LID9 ^@ Subunit ^@ Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_011910 ^@ http://purl.uniprot.org/uniprot/E3MLC3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. http://togogenome.org/gene/31234:GCK72_012032 ^@ http://purl.uniprot.org/uniprot/E3MK24 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/31234:GCK72_016619 ^@ http://purl.uniprot.org/uniprot/E3MTQ7 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/31234:GCK72_000612 ^@ http://purl.uniprot.org/uniprot/E3M313 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Membrane http://togogenome.org/gene/31234:GCK72_019998 ^@ http://purl.uniprot.org/uniprot/E3LHC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/31234:GCK72_001136 ^@ http://purl.uniprot.org/uniprot/E3LXW8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/31234:GCK72_003482 ^@ http://purl.uniprot.org/uniprot/E3M8P4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. http://togogenome.org/gene/31234:GCK72_016253 ^@ http://purl.uniprot.org/uniprot/E3MY69 ^@ Similarity ^@ Belongs to the TAF11 family. http://togogenome.org/gene/31234:GCK72_008797 ^@ http://purl.uniprot.org/uniprot/E3M8I1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF7 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_017099 ^@ http://purl.uniprot.org/uniprot/E3NCZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FARP (FMRFamide related peptide) family.|||Secreted http://togogenome.org/gene/31234:GCK72_025693 ^@ http://purl.uniprot.org/uniprot/E3MBZ5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/31234:GCK72_002686 ^@ http://purl.uniprot.org/uniprot/E3LV42 ^@ Similarity ^@ Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. http://togogenome.org/gene/31234:GCK72_007560 ^@ http://purl.uniprot.org/uniprot/E3M919 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unkempt family.|||Cytoplasm http://togogenome.org/gene/31234:GCK72_008825 ^@ http://purl.uniprot.org/uniprot/E3M8G3 ^@ Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. http://togogenome.org/gene/31234:GCK72_002955 ^@ http://purl.uniprot.org/uniprot/E3N944 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/31234:GCK72_013969 ^@ http://purl.uniprot.org/uniprot/E3M7E6 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/31234:GCK72_006521 ^@ http://purl.uniprot.org/uniprot/E3LQ92 ^@ Function ^@ Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. http://togogenome.org/gene/31234:GCK72_006410 ^@ http://purl.uniprot.org/uniprot/E3LQM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EAF7 family.|||Nucleus http://togogenome.org/gene/31234:GCK72_001072 ^@ http://purl.uniprot.org/uniprot/E3LY28 ^@ Similarity ^@ Belongs to the eIF-2-alpha family. http://togogenome.org/gene/31234:GCK72_015548 ^@ http://purl.uniprot.org/uniprot/E3NN12 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_008443 ^@ http://purl.uniprot.org/uniprot/E3NAE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Membrane http://togogenome.org/gene/31234:GCK72_011955 ^@ http://purl.uniprot.org/uniprot/E3MKA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/31234:GCK72_025097 ^@ http://purl.uniprot.org/uniprot/E3NAS4 ^@ Similarity ^@ Belongs to the GST superfamily. Zeta family. http://togogenome.org/gene/31234:GCK72_024239 ^@ http://purl.uniprot.org/uniprot/E3LEJ2 ^@ Similarity|||Subunit ^@ Belongs to the cuticular collagen family.|||Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links. http://togogenome.org/gene/31234:GCK72_016803 ^@ http://purl.uniprot.org/uniprot/E3MQ72 ^@ Similarity ^@ Belongs to the PAF1 family. http://togogenome.org/gene/31234:GCK72_016334 ^@ http://purl.uniprot.org/uniprot/E3N5U9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BCAP29/BCAP31 family.|||Endoplasmic reticulum membrane|||May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.|||Membrane http://togogenome.org/gene/31234:GCK72_024216 ^@ http://purl.uniprot.org/uniprot/E3LEL7 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_009424 ^@ http://purl.uniprot.org/uniprot/E3LSG6 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/31234:GCK72_008351 ^@ http://purl.uniprot.org/uniprot/E3MFS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Golgi pH regulator (TC 1.A.38) family.|||Membrane http://togogenome.org/gene/31234:GCK72_000509 ^@ http://purl.uniprot.org/uniprot/E3MX48 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. http://togogenome.org/gene/31234:GCK72_005514 ^@ http://purl.uniprot.org/uniprot/E3LFQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CLPTM1 family.|||Membrane http://togogenome.org/gene/31234:GCK72_019439 ^@ http://purl.uniprot.org/uniprot/E3LKR9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.